LOCUS       gnlProkkaNCJMPBHN_49    5719 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NCJMPBHN_49.
ACCESSION   gnlProkkaNCJMPBHN_49
VERSION     gnlProkkaNCJMPBHN_49
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 04:44:36
            Original ID  :: gnl|Prokka|NCJMPBHN_49
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5719
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5719
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2:2522]"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2522
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..5719
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5719
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             3..2522
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     64.2; E-value: 1e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_1"
                     /sec_met_domain="Pkinase (E-value: 2.9e-15, bitscore: 44.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.1e-22, bitscore:
                     67.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHYIFTGTTLPQSGWKGHIACLPQDMKKVFKIVYNLLTEEECTF
                     KVARSKEVYKALNDPHTSVTEANKFITFYPENDSKFRRIIKKLANTLSNFKAPTIFTDY
                     QLPNYSPVQFRYGAFKELKKWDEVNKKFIDLMTLPNGTITEDNRDEEFKVPDSVTLPFF
                     KSDSSWLEDTNELDNKNISKYNFISILSQKNKGDVYLANHKTKKVIIKSANPFVQNSIT
                     SSSAKQLLANESQFLTILQNSGTVPKLLDRFTVNKVDFNVTSYIDGVSLDAPIASKKKE
                     EIIYALCDTVYKLHSRNIVIGDLTNSNFIFSNGTCYLIDLEYLSFTYQNKYREGYTPYY
                     IPYNHSKTQLSQKEDIFSLAVSILAILIGNLPKYNSHDISNAIKALKREIYVASSIDTN
                     NLELYLIVNYLLNLAKSDNLYAPEQIKNIQSKIKPLDKDILKRSKYSCHKLINILNYNQ
                     NKLIDKISNKNLLDKNDFQIKWWQSNEFGSQISPLSIQHGVIGVNCALGRPAIHNLNKL
                     RNIIQNSLNFSYNDSYLFGSSGLLWELGYNYRKGTLTTKDFEKAINTIINSWNVTNTSI
                     DFALGTAGKLYSLIFVLSLVKEGDMTVVKMKAKTLHDSLLKSVLNDQHASLSTTFDRIN
                     FAHGLAGTAYVLLMSALMFNDHKAFIVAKNKLKYIDNFLAQNLKCDSNFNNYMYFSWCE
                     GISGIGDALVRAQSILNNKYKSIPLIYSCLIKNCLKLDGCWCHGRSSIINFLSDLFVRT
                     NDTNVYHHIFMISLYEISTALNFKNNTLKFIDETGYLHTIDFGVGQVGIMKTIIDALSK
                     KDRLFFLDTKQEQQLSQKFFSSSYKTK"
     CDS             2928..3875
                     /locus_tag="ctg49_2"
                     /transl_table=11
                     /translation="MKRLIGTIIALFAFLTIAFVSEVNKKNAEKKTPTVGILQTMSHPA
                     LDQIHRGIIQGLKDEGYIEGKNLKIDFQNAQGDQSNLKSMSDRFSQENATVTIGIATPA
                     VQSLANTSGNIPVVMGAVSDPLGAHLVKSLAHPGGKITGVQDRQPIASQLALMQEILPK
                     AKNIGVIYTSSDDSSASEYREFRRLAEAKGLKVIPYTITSTNDIEQVAQTMVGKVQAVY
                     VPTDNTVASGIATLLKATNSAKIPVFPAADTMVKSGGLATRCVSQFDMGILTGKXXXXX
                     XXXXXXXXXXXXXXXXXWPRFALGRSSLRPLPNF"
     CDS             3895..4695
                     /gene_functions="transport (smcogs)
                     SMCOG1113:inner-membrane translocator (Score: 55.9;
                     E-value: 5.7e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_3"
                     /transl_table=11
                     /translation="MTVEGTFPFGAAICVSALVHGVNPLAATILSFFAGMVTGLVTGLL
                     YTKGKIPVLLAGILTMTGVYSVNLRILGKANVGLLNKNTLLNGQLLQKLPINFPTIVVG
                     LIIAIIVIVLLAVFLDTDLGQAFIATGDNEKMAQSLGINTDNMKILGLMLSNGLIGLAG
                     GLLAQNGGYADVNMGIGTMVIGLAAIIIGEVVYGNLSLTARLVAVVIGSIIYRLILLLV
                     LQLGFSTNDFKLISAIILAICMMLPLFEQKFRTRKLLKKGVEKP"
     CDS             4692..5453
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 179.4; E-value:
                     1.5e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_4"
                     /transl_table=11
                     /translation="MSTILDLQNITTTVNAGTNEEKQILKNINLKLEDGDFVTLLGTNG
                     AGKSTLLNIINGSIFPTSGKILLKDQDLTNLSEVKRAKYIAQVFQDPKMGTAPRMTVAE
                     NLLLATKRGEHRGLRLRGLDKHMQEFKRQAAQLPNGLNERLNTFVGNLSGGQRQTLSFL
                     MATIKRPDLLLLDEHTAALDPNTSRELLELTDKVVQEEHLTCIMITHQLKDAIKYGNRT
                     IILNNGRIVFDVKGDDKKRLTEEDILQYFTD"
ORIGIN
        1 tgtggaagca ctatatattt actggtacca cattgccaca atctggctgg aaaggacaca
       61 ttgcatgttt accccaagat atgaaaaagg tttttaaaat cgtctacaac ctattaacag
      121 aggaagagtg cacttttaaa gttgcaagat caaaagaagt ctataaagct cttaacgatc
      181 ctcatacatc agtaactgaa gcaaataaat ttattacttt ctatccagaa aatgattcta
      241 aattcagaag aattattaag aaattagcta ataccttatc taatttcaag gctccaacta
      301 tttttaccga ttatcagctt cctaattata gccctgttca atttagatat ggtgctttta
      361 aagagctaaa aaaatgggat gaagtaaaca aaaaattcat tgatttaatg accttaccaa
      421 atggaaccat tacggaagat aatagagatg aggaattcaa agtgcctgat agcgttactc
      481 taccattctt caaatcggat tcatcttggt tagaagatac caatgagctt gataacaaaa
      541 atataagtaa atataatttt attagtatac taagccaaaa aaataagggt gatgtttatt
      601 tagcaaatca taaaacaaaa aaagtaatta ttaaatcagc aaacccattt gttcaaaatt
      661 ctattacctc atcaagcgca aaacaattac tagcaaatga aagtcaattt ttaactatcc
      721 tacaaaattc tggaactgtt cctaaattat tagatagatt tactgtaaat aaagtagact
      781 ttaatgtcac ttcatatatt gatggggttt ctttagatgc acctatagca tctaaaaaga
      841 aggaagaaat tatttatgca ttatgtgata cagtatacaa gttacatagt aggaatattg
      901 ttattggaga tttaacaaat agtaacttta tttttagtaa tggtacttgc tatctaattg
      961 atttagaata cctttcattt acatatcaaa ataaatatag agaaggatat actccgtatt
     1021 atatccctta caatcattct aaaacacagt tatcccaaaa agaagatatt ttctcattag
     1081 ctgtatcaat cttagctata ttaatcggta atttaccaaa atataattct catgatattt
     1141 cgaatgctat taaagctcta aaaagagaaa tatatgtagc atcttctatt gataccaaca
     1201 acttagaact atatttgata gttaactact tattaaattt agccaaaagt gataacttat
     1261 atgcgcctga acaaattaaa aacatacaat caaaaattaa gccacttgat aaagatatat
     1321 taaaaaggtc aaagtatagt tgtcataagt tgattaatat tttaaattat aatcaaaata
     1381 aattgataga taaaatatcc aacaagaatc ttttagataa aaatgatttt caaataaaat
     1441 ggtggcaatc taatgagttc ggcagccaaa taagtccatt atctattcaa catggagtaa
     1501 taggagtcaa ctgtgcttta ggacgtccag ctatacacaa tctaaacaaa ttacgtaata
     1561 taatccaaaa tagcctaaat ttcagctaca atgatagcta cttattcgga agttcagggt
     1621 tgttatggga attaggatat aactatagaa aggggaccct gactaccaaa gactttgaaa
     1681 aagctataaa tactattata aacagttgga atgttacaaa tacctctatc gattttgcat
     1741 taggtactgc aggtaagctc tattctttaa tatttgtctt atcgttagta aaagaaggtg
     1801 atatgacagt agttaaaatg aaagctaaaa ctttgcatga tagtttatta aaaagtgtac
     1861 ttaatgatca acatgcctca ctatctacta cttttgacag aattaatttt gctcatggcc
     1921 tagctggtac tgcctatgta ttgttaatga gcgcccttat gttcaatgat cacaaagcat
     1981 tcatagtagc taaaaataaa ttaaaatata ttgataattt tttagcacaa aatctaaaat
     2041 gtgactctaa ctttaacaat tatatgtatt tctcttggtg tgaaggaatc agtggaattg
     2101 gtgatgcact agtaagagca caatcaatac taaataataa atataaatct atacccttaa
     2161 tttattcatg ccttattaaa aactgcctaa aattagatgg gtgttggtgt catggcagaa
     2221 gtagtataat caacttttta tcagatttgt ttgtaagaac aaatgatact aatgtatacc
     2281 atcatatttt tatgatctcg ttatatgaaa tttcaactgc attaaatttt aaaaataata
     2341 ctttaaaatt tatcgatgaa actggctacc tacatacaat agactttggg gtcggccaag
     2401 tcggaataat gaaaaccatt atagatgctt tatcgaaaaa agatagatta tttttcctag
     2461 ataccaagca ggaacagcaa ttatcccaaa aattttttag ctctagttat aaaacaaaat
     2521 aattcctaaa aacatttatc atcgcatttt atattaattt ggctaattta ggacaaattt
     2581 ctagtgatct tctcataaga tagtaatact tttagttatc gcgaatcata ataagaccaa
     2641 ctcagcaaaa aatcatttga catctttctc ataattactt aaaatttagc taacaaattt
     2701 gaacgaaagg aagattttat catgattaaa tttacagcaa tcaatcgttg gcaattccag
     2761 cactagagtt gtttctgttc gtgaagtaca gatgcgactc attaagatcg tatctgtgct
     2821 ggtaaaatct tcaagaaata ttgcccgcac ggaaaataac gtgcgggttt tgttttaggc
     2881 atttcccgaa aaaaggaagt gccttttttg tttgaaggag aaaaagaatg aaaaggttaa
     2941 tcggaacaat tattgctctt tttgcttttc tgacaattgc ttttgtcagc gaagtaaata
     3001 agaaaaatgc ggaaaagaaa acgccaactg tcggtatctt gcaaacaatg agccaccccg
     3061 ctctagatca gatccatcga ggcattattc aaggacttaa agatgaagga tatatcgaag
     3121 gaaaaaatct taaaattgat tttcaaaatg cccaaggtga tcaaagtaat ctgaaatcaa
     3181 tgagcgatcg ctttagccag gaaaacgcaa ctgtaactat tggaattgcc actcctgctg
     3241 tccaatctct agctaatact tctggcaaca tccctgtagt tatgggcgcg gtcagcgatc
     3301 ctcttggggc ccatttagta aaaagcctag cgcatcccgg cggtaaaatt accggtgtcc
     3361 aggaccgcca gccaatcgcc agccagctgg ccttaatgca agaaattcta cctaaagcca
     3421 aaaacatcgg tgtcatttac acctcaagtg atgattcatc agcatcagag taccgtgaat
     3481 tcagacgact agctgaagca aaaggactta aagttatccc ttacactatc acttcaacca
     3541 atgatatcga acaagttgcc caaaccatgg taggcaaggt tcaagcagtt tatgtcccaa
     3601 ccgacaatac tgtagctagt ggaattgcca ccttattaaa ggctactaac agtgccaaga
     3661 tcccagtttt tcctgctgcc gatactatgg ttaaaagtgg tggtctcgct accaggtgtg
     3721 tcagtcaatt cgacatggga atcttaactg gaaaaannnn nnnnnnnnnn nnnnnnnnnn
     3781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ttggccaagg tttgctctgg
     3841 ggcgttctag ccttaggcct ctacctaact tttagaattt taaatttccc agacatgact
     3901 gttgagggaa ccttcccctt cggtgccgca atttgtgtta gtgcgttagt tcatggcgtc
     3961 aatcctttag cagctaccat tctttccttc ttcgctggca tggtcactgg cttagtcacc
     4021 ggcttactgt atactaaagg aaaaatccct gttcttttag ctggtatttt aacgatgacc
     4081 ggtgtctact cagttaatct tagaattcta ggcaaggcta atgtaggttt acttaacaaa
     4141 aatactttac taaacggtca gcttttacaa aaattaccga tcaattttcc tactattgtt
     4201 gttggtttga tcattgccat tatcgtcatc gttttgctag cagttttcct tgatactgat
     4261 cttggtcaag cctttattgc cactggtgac aacgaaaaaa tggctcaatc acttggcatt
     4321 aataccgata atatgaaaat cttgggtcta atgctttcta atggcttgat tggcttagct
     4381 ggtggattat tagcccaaaa cggtggttac gctgacgtta acatggggat cggtactatg
     4441 gttatcggac tagctgccat cattattggt gaagtcgttt atggcaattt aagtttaact
     4501 gcccgcttgg tagcagttgt tatcggtagt attatttatc gccttatctt actcctagtc
     4561 ctccaacttg gctttagtac caacgacttt aaattgattt ccgctattat tcttgctatt
     4621 tgtatgatgc tacctttatt tgaacaaaaa tttcgcactc gtaaattatt aaagaaaggc
     4681 gttgaaaaac catgagtact attcttgatt tacaaaatat taccactacc gttaatgctg
     4741 gtaccaatga agaaaagcaa atcctcaaaa atattaatct aaaacttgaa gatggagatt
     4801 ttgttactct tttaggaacc aacggtgctg gtaaatcaac gctactaaat attatcaatg
     4861 gctctatttt tcctactagc ggaaaaattc tgctcaaaga ccaagattta accaatcttt
     4921 ctgaagtaaa acgcgctaaa tatattgccc aagtattcca agatcctaaa atgggtacag
     4981 ctccgcgaat gactgttgcg gaaaacttat tacttgcaac caaacgaggt gaacaccgcg
     5041 gtctgcgttt aagaggccta gataaacata tgcaagaatt taaacgccag gcagcccaac
     5101 ttcctaacgg attaaatgaa cgcttaaata cttttgtggg taatctttct ggtggtcaac
     5161 gacaaacatt aagtttttta atggcaacaa ttaagcgccc tgatttgctc ttactagatg
     5221 agcatactgc ggcgttagat ccaaatacta gccgcgaatt gcttgaacta actgataaag
     5281 ttgtgcaaga agagcatttg acttgcatca tgatcactca ccaattaaaa gacgcaatca
     5341 aatacggaaa ccgcaccatc attttaaaca atggtagaat cgtttttgat gtcaaaggcg
     5401 acgacaaaaa acgcctaact gaggaggata ttctgcaata cttcacagat tagaacgtta
     5461 ttttaggatt ataagttaag agtgaacgac agctataata tgaacactgt gaatttgcgg
     5521 attttcttat tataataaga gccgaggtca tcgttaaggg acttatacca aaaatctccg
     5581 cagttattca aaatgaatag ctgttttttt ctgccctttt tacgaaattc cgtaaaacgt
     5641 tattctagca acatttaccc agcaaaaata tttttctaaa aaatgtgctt ttttccttgt
     5701 attatataac gtacgttat
//
