LOCUS       c00013_gnlPro..        14757 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LHAFHHDF_13.
ACCESSION   c00013_gnlPro..
VERSION     c00013_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 05:47:46
            Original ID  :: gnl|Prokka|LHAFHHDF_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14757
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14757
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6067:8699]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6068..8699
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..14757
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14757
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(82..372)
                     /locus_tag="ctg13_1"
                     /transl_table=11
                     /translation="MNDFTKDFAQALFNPDKINDLLRKELQQAVNNLLEAELTAFLGYD
                     PYARNGWNTGNSRNGAYFRKVDTQFGPIEVQVPRDRNGQFHQHTLPDYQQH"
     CDS             complement(448..1503)
                     /locus_tag="ctg13_2"
                     /transl_table=11
                     /translation="MTMRSLGLSIYPDHTNFEDNTKYLELGHKYGFTRIFMSMLEVQGS
                     PEETPAKYKKIIDYGNKLGYQTFLDVSPQLFKKLEIDYSDLKFFADIGAAGIRLDEAFD
                     GATEAMLSYNPYGLIIELNMSNNADYLNNILSYQASQPFIYGCHNFYPQRGTALPYDFF
                     LDCSTRFKNFGIHSAAFVSSQVGKVGPWNVEDGLPTLEEDRDLPIEVQAMHLFASNMID
                     DVIIGNAYASEAELKALFELNRYQLKLHVNYVSDINEIEKTIVEKPQHFRRGDLTKAVI
                     RSTMQRVTYKDIPNPIHDNEVEFQRGDVIIGNDNFGHYKNELQIVLEPHKEPRDCKIVC
                     VRMNDSLNLFL"
     CDS             1779..2159
                     /locus_tag="ctg13_3"
                     /transl_table=11
                     /translation="MALAVFISATSAYLTMTVFARSFASFIAAHQWEVWLLILLPIVYG
                     VTFAFLTEAYSGHNVASATVFVIMAIIGTVTKKDLSRIGSYASAALIGLIVAMVINLFL
                     HNPIIDYIFSTIAVIIFTILTA"
     CDS             2429..2578
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MAIVALLTLVGEISVIPANLQNTSYRKKEGVSNMTGLKLLVISDQ
                     KYFM"
     CDS             2578..2676
                     /locus_tag="ctg13_5"
                     /transl_table=11
                     /translation="MRGHNYRMNRENAIFFKSKAAARAAGYRESKR"
     CDS             complement(2744..5017)
                     /locus_tag="ctg13_6"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGEVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNR"
     CDS             5146..5994
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg13_7"
                     /sec_met_domain="LysR_substrate (E-value: 1.9e-30,
                     bitscore: 96.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.6e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIDA
                     I"
     CDS             6068..7297
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_8"
                     /sec_met_domain="Amidinotransf (E-value: 8.1e-109,
                     bitscore: 354.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELPTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEIVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             7308..7712
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_9"
                     /sec_met_domain="OTCace_N (E-value: 7.3e-38, bitscore:
                     120.4, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVN"
     CDS             7732..8061
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_10"
                     /sec_met_domain="OTCace (E-value: 1e-25, bitscore: 81.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLADFMTMKEKFGHLKGLTLAYVGDGRDNVADSLLVCGSMLGVNV
                     HIVTPKPLFTHPDVQKIAQNFAQDSGSKNLITDDIAQGVKGANVVYTDVWVSMGEMIGL
                     NELNY"
     CDS             8088..8699
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_11"
                     /sec_met_domain="OTCace (E-value: 1.7e-17, bitscore: 54.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 1.5e-21, bitscore:
                     67.5, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQMTGTPDDQLIFMHCLPAFHDRTTQVGEEIYEKYGLNEMEVTYE
                     VFNSKYAWQFTEAENRLHSIKAVMAATLGNLFIPIACGGGGIPVIVKDGHLRGVAGVID
                     KDFSAAKMAEDINADELVILTTVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGS
                     MKPKIEAAIEFVEKTGNLAIITSLSNANKLADGVGTIVYN"
     CDS             8713..9249
                     /locus_tag="ctg13_12"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDIKMNI
                     PGPIKNNRYLTKMFMFGINKLENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFEDQTSLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPSKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             9329..10531
                     /locus_tag="ctg13_13"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMKLKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASCPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTNDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     MSYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPE
                     QNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRK
                     VAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDY
                     F"
     CDS             10547..10708
                     /locus_tag="ctg13_14"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             10710..11315
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_15"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-13,
                     bitscore: 41.5, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASGSGYFILNENTARLINTADL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             11371..11481
                     /locus_tag="ctg13_16"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             11447..11953
                     /locus_tag="ctg13_17"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             12019..12711
                     /locus_tag="ctg13_18"
                     /transl_table=11
                     /translation="VTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFSEFIFTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(12810..12938)
                     /locus_tag="ctg13_19"
                     /transl_table=11
                     /translation="MKGMRTLIKLLLIGGSFLTLGLMAISSVLINKPAVAKVKHRH"
     CDS             13282..14319
                     /locus_tag="ctg13_20"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKKPA
                     SKSKRVRTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNYE
                     FDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLID
                     VLRKM"
     CDS             14571..14756
                     /locus_tag="ctg13_21"
                     /transl_table=11
                     /translation="MNDFTKDFAQALFNPDKINDLLRKELQQAVNNLLEAELTAFLGYD
                     PYARNGWNTGNSRNGAY"
ORIGIN
        1 actgtttcct attggtgcgg gtagttgccg ggtgtgtatg cgcatggagg aagacttgat
       61 gatcatgctt gacaagatat cctagtgctg ctggtagtca ggcagcgtgt gctgatgaaa
      121 ttgaccgttg cgatcccgag gcacttgcac ttcaattggg ccaaattgcg tatcaacttt
      181 gcggaaataa gcaccatttc tagagttgcc agtattccag ccatttctgg catagggatc
      241 atagcccaga aatgcagtca attcagcttc taacaagtta ttaacagcct gttgtagctc
      301 tttgcgcaat aaatcattta ttttgtctgg attgaataga gcttgagcaa aatctttggt
      361 aaaatcattc atgaaggagt tcttctttct gtatgttttt ttttgttcaa accaatcata
      421 cgagaaagga actccttttt ctaatgttta aagaaataaa tttaaggaat cattcatcct
      481 tacacaaact attttacagt ctcgcggttc tttatgcggt tcaaggacaa tttgtaattc
      541 atttttataa tgaccaaaat tatcattgcc aataataacg tcaccgcgtt gaaattctac
      601 ttcgttatca tggataggat taggaatatc tttataggta actcgctgca tagttgagcg
      661 aataaccgcc ttagttaggt cacctcggcg gaagtgttgt ggcttttcaa ctattgtttt
      721 ttcaatttcg ttaatgtcag atacataatt tacgtgtaat tttaactgat agcgatttaa
      781 ttcaaagagt gctttaagtt ccgcttcact agcataggcg ttgccaataa ttacatcatc
      841 aatcatattt gaagcaaata aatgcattgc ttgtacttcg attggtaaat cgcggtcttc
      901 ttctaaagta gggaggccat cttcaacatt ccaaggacca actttgccaa cttgactaga
      961 gacaaaagca gcagagtgaa tgccaaaatt tttaaaacgt gtactacaat ctaagaagaa
     1021 atcataaggt agagccgtgc cgcgctgtgg ataaaaatta tggcagccat agatgaaagg
     1081 ttggctggct tgataagata aaatattgtt gaggtagtca gcattattac tcatgttaag
     1141 ttcaataatt aggccataag gattgtatga aagcatggcc tctgttgcac cgtcaaaagc
     1201 ttcatcaagc cgaataccag ctgcaccgat atctgcaaaa aatttcagat ctgaataatc
     1261 aatttctaat ttcttaaaga gctgaggtga tacatcaaga aaagtttggt agcctaattt
     1321 attgccgtag tcaataatct tcttatattt agctggagtt tcttcagggc taccttgtac
     1381 ctcaagcata ctcataaaaa tacgagtaaa gccgtattta tgacctagtt ctaagtattt
     1441 cgtattatct tcaaagttgg tatgatctgg ataaatggac agaccaagtg atctcattgt
     1501 cataaaagta cctctttctt attaatatgt ctataccaat tagatcaagc ttagcattat
     1561 aggtctagtc caaagcaaga aaagcagtga aataatacgc tcaaaatata gtatgctgat
     1621 agcaattcgt ctcgttactt tttcagtaaa ccaggtgtta tattaggtgt acagagtatg
     1681 tttaaaaaga gggaaaatca agatggaaaa ttgtgatcaa gagtctgagc gacgacaagt
     1741 ggatgcactt gggttaaatc tttttttgag tagaatatat ggccttggcg gtttttattt
     1801 cagctaccag tgcttatcta acaatgacgg tttttgctag atcatttgct agctttattg
     1861 cggctcatca atgggaagtg tggcttttaa ttttactgcc aattgtttat ggcgttactt
     1921 ttgcttttct taccgaggct tatagcggac acaatgttgc ttcggctact gtttttgtca
     1981 ttatggcaat tatcggaact gtaactaaaa aagacctgag tcgaattggt tcttatgctt
     2041 ccgctgcttt aatcggctta attgtagcaa tggtaattaa tttgttttta cataatccta
     2101 taattgatta tattttttca actattgcgg tcattatttt tactatattg acggcatagg
     2161 atgctcagcg catgaagaat atttatttac gctatggtga tgatatttca actaatggac
     2221 tagcagtgct gggtgcactg cagttatatc ttgactttgt taacttgttt ttacaatttc
     2281 tagatatttt tagcgcaagt gaaagtaatt aaaatttgac tttatgttaa ttcaaatgaa
     2341 ataagcacaa tctaatatat aagcgtatgc tacgaagata tagttattat taggaaggtt
     2401 tttaatgaaa aaatgcaaaa atttgttgat ggcaattgtt gcattattaa cgttagttgg
     2461 ggaaattagt gttatacctg cgaatctaca gaatacatct tatcgtaaaa aagaaggcgt
     2521 aagcaacatg acaggactaa aattgttggt aataagcgat caaaaatatt tcatgtaatg
     2581 cgtggacata attaccgaat gaatcgcgaa aatgcaattt tctttaagag caaagcagcg
     2641 gctcgtgcgg cgggatatcg tgagtcaaaa aggtaaacga aaagcacttc caagaatgta
     2701 atttcttaga agcgcttttt taatgcaaaa ttgaattaat aatctatctg tttttcatca
     2761 caggttggta aattaagtcg attattatgg cagcaataat cgctacaatt acggtgattg
     2821 ctagattttg aatagaaatt tggaccattg cccaaccaca aagagctaag ataaaggtca
     2881 atagaacatc tgcaatttga acactaccaa ccaacttgga tgggtaatct tgccaaaagt
     2941 acttacgagt tctagtaatc aaaacaatca acattgcgct aagaactagg tatacgtaaa
     3001 ccatagtaga aacagcaccg tgactccaac cgtgtgtgtt taagaaccaa acaaacccaa
     3061 taccgattaa agtccaacca gcagctagtg aaaaggcgat cttagcaagc ttagccatat
     3121 tccagttttc tggcttataa gtaatgtgag tccggtcggt cccaatcatc atcgtaacca
     3181 tattgttcat aatggtatag ataaccattg cattcaaggc cattgggatg tagtcaaaga
     3241 aaagatagcc aaaagttaac agcatcgtta attcagcagt tctagcaagc ttggttagtg
     3301 accaagtagt cattctttgg tatacgcgat gtccagcgtc taaaatttta acaattgagc
     3361 ctagaccatc gtctagtaat accattttac ccgaacgctt agctacgtca gcagcatttg
     3421 aaaccgcgat tcctacttca gcttgtttta atgcaggtgc gtcgttaact ccgtcaccag
     3481 tcatccctac gatatagcct ttttcttgga aaagctttac catcttgagt ttatcttctg
     3541 gtaaaacatc agcaataccg gccaaatcat taatatcagt attttcattg aaatcgtgaa
     3601 tcgaaattac ttcaccagtt aaatcaactt gttctgccac tgcagcagcg gtcttttgat
     3661 tgtcaccagt taacataatt gggcgaacgc cacgtttctt gagttcagcc aaagctgctt
     3721 tagagtctgt tctaacttta tcttgtaaga tgaagacacc agctaactta tcgtcaatca
     3781 agactgccac tgagcgtcct gccttgaaat taattccaga aatttcttca tcggcatgtt
     3841 tatcgatcaa ggataattgc ttaaatgaac caagctttac attatgtcca gcaacatcag
     3901 ccatagaata accagtgtca gaagtaaatg gagtaaagtt ttcagcattc atgactggaa
     3961 tgttattttc tactaagtat tcatcgattg ctgtatcgat aataccagca ttacgtttat
     4021 cagttgcggc tccagctaaa gcaagcacgt ctttatcagg caagtcactt agatcagtcc
     4081 aagcggctac ggcagttttg ttttccgtaa ttgttccagt cttatcaagt aaaagcaagt
     4141 tcaagttagc tgcgtcctga attccagtta ggtcagaagt caggactcct tctttactta
     4201 agcgggttgc ttcaaatgag ttggataaag caaaagttga tggcattgct acaggaattg
     4261 aagcaataaa catcattgcc aggaatggca acatattaat aaaggtattg aaattaccgc
     4321 ctttgaagaa ggaggcgata ataataacta aggttaaaac accatctagt aagcaaaggt
     4381 agtagataat cttagtcaaa agttgttgta agtgaccagg agcagcggaa ttgttgatca
     4441 aattaatcgt cttaccgctt ctagaatctt tacctgtagc agtaacaaca gctaggccat
     4501 caccttcaac aactgtagta ccggcaaagg cggtgtcatc aattgctttc ttaactggtt
     4561 tagattcacc tgtaattgag ctttcatcac aagctaagtt accgtcaaca attttaacat
     4621 ctgctgcgag tacgtccccg cgtttaagtg agattaaatc gcctttaact agttgtttag
     4681 aatcaagttt gatccacttg ccatcgcgtt caactgatac agtaggagtc aacttgtgtg
     4741 aaatattatt taaaactcgt cttgattgct ttttcttaga tgcaccgtta aatgcagcaa
     4801 ataaaagcat caacaacacg aataatgatt ggacccattt gcccaagata cattctagaa
     4861 ttaaagcagc ttctagaatc caagcggata ggttccataa cttagacaag aattctttaa
     4921 agaaattata ttcaggctct ggtacttcat ttaagccatc ttcttttaag cgcttgtctg
     4981 cttcggcttg agttaagccg tgaaatttat cagacattat tttccctcca aatctacctt
     5041 aataaggtag cacagatatt gctatgaata aaatactaaa atacaatata agatattaaa
     5101 tattttaata tcactatcaa ttgaaataaa aaaaggataa ataatatgaa tctaaaacag
     5161 ttacgttatt ttctagttgt agcagaagaa aagcagatta cagcagctgc taagcgcttg
     5221 tatattgcac agccaccatt aagctatcaa ttaaaacaat tagagaaaga gttgggcgcg
     5281 caattattta aaagaacggc acatggtatt gagctaactg atgtgggaca aatttttcaa
     5341 agctatgcca atgaaattat ttctctagct caaaatgctg aaaaccaagt acataagact
     5401 atttccggtg aattgggaac gattgcaatt ggaatggcat cttcctcaac gggcttgata
     5461 ccaatgaatt cttttaatga attacgaaaa tattatccgg aaatttcttt tgatatttat
     5521 gaagataata cttatggcat cctggataaa ttagaaaaaa agacaatcga tctaggcatt
     5581 gtacgaacgc cttacaacca gacaggttta aatactaaga ctttaacaac tgaaaaaatg
     5641 atggctatta gtgtagaccc agattttcag caaaaaaaag aattacgcat taaagatcta
     5701 gcagatcagc cgttgattat ttatcgccgc tttgaggata tttttaatca aacttttgca
     5761 catcatgggc ttaagccatt ttatgcggtt aagtgtgatg attcacggac agcaattact
     5821 tgggctaaga gaaaaatggg agtagcgcta gtaccagaat caattgcgac aacttatgcc
     5881 caagaaaata tgatcgcaat taaacatgct aattggataa cacatttgca gctggtttgg
     5941 cgtaaagatc atcaagttac acctttaatg aaaaaaatca ttgatgcaat atgataatac
     6001 tgtaactttt gcctaattga tccataatca atgtaaacgg atacaataat taatagaagg
     6061 cggttgaatg tcgagtccga ttcatgttta ttcagaaatt ggtaagttaa aaacggtgat
     6121 gttacatcga ccgggaaaag aactagaaaa tctagcccca gatattttgc atcgaatgtt
     6181 aattgacgat attccttatc tgaagattgc ccaagaagaa catgatgctt ttgcgcatgt
     6241 attgaggcag caggggatca aagtattata tcttgaggat ttattagcag aatctttaac
     6301 agatgagaaa gttcgtcggg cattcttaga tcagttactg gatgaatcaa gtattaaaaa
     6361 acaggatcct ttgcatcaat tattgctgaa ctatctccaa gaattgccaa ctaaggaaat
     6421 ggtaaaaacg gtgattgctg gaattagaaa aagtgcgatt cataattcta ccccatcttt
     6481 agcagatttg gctgaggacc cagattaccc tttttatctt gatccaatgc caaatgtata
     6541 ttttactcga gatcaacagg ctgcaattgg ttcagggatg accattaacc ggatgacttt
     6601 cagagctaga cgacgtgaat cattatttat ggaaacaatt ttgaaaaatc atcctgattt
     6661 caagaacgca actattccag tttggcgtga ccgttatcat catggtcgcc ttgagggcgg
     6721 ggatgaacta gttctaaata accatgtgtt agctgtaggt atttcacaac gcacttctgc
     6781 aactgcaatt actgacttag ctcataattt atttgatcat tcaagttatg atacgatttt
     6841 agcgattaag attccgcaca atcatgctat gatgcacctt gatacagttt ttacaatgat
     6901 taattataat caatttacgg ttcatccctt tattttagat aaagccggca aaattgatat
     6961 ttatgttcta cagcccgatg atcacaacgg tgtaaaaatc acagaaaaga atgatttggt
     7021 gcaggttttg aaagaaaact tgcatttaag cgaattggat ttaattccaa ctggcggtgg
     7081 tgatccaatt gccgcaccac gtgagcaatg gaatgacggc tcaaatacct tggcaattgc
     7141 accaggtgaa atcgttactt atgatcgtaa ttatgtatcc aatgatttgt taagaaaaca
     7201 tggcatcatc gttcatgaga ttcggtctag tgaactctca cgtggtcgtg gcggtcctag
     7261 atgtatgtcg tgtccgttga ttcgtgaaga tttataagag gcaaaaaatg aaatatttac
     7321 aaaatgtttt tcaaggtaga agttttctcg attgtaaaga ctatactcca gctgaaattt
     7381 catatttaat tgattttgca ttacatttaa aagaacttaa aaaagagcat atcccacatg
     7441 aatatctgaa aggtaaaaat attgcactac tttttgaaaa agcctcaact aggacgcgat
     7501 ctgcttttgt agtagcttgt aatgatttag gtgctcatcc agaatatcta ggcgcaagcg
     7561 agatccactt aggtaaaaaa gaaagcgtca aggatacggc taaagtccta ggctcaatgt
     7621 atgatggaat tgaatatcgc ggttttgctc aagaagatgt agaagagctg gctaaatatt
     7681 ctggcgttcc tgtttggaaa tgggttaact gataaatggc atcctactca gatgttggca
     7741 gattttatga ccatgaaaga aaagtttggt catttgaagg gcttaacttt agcttatgtg
     7801 ggtgatggcc gcgataatgt tgccgacagt cttttagttt gtggctcaat gttaggtgtt
     7861 aatgtacata ttgttacacc caagcctttg tttacacatc ctgatgtaca aaaaattgct
     7921 caaaattttg cccaagattc aggttcaaaa aatttgatca cagatgatat tgctcagggc
     7981 gttaaaggag ccaatgttgt ttataccgat gtttgggttt cgatgggtga aatgattggt
     8041 ctgaacgaat taaattatta aagccatata cggtcacaat gaaaatgatg caaatgactg
     8101 gtacaccaga tgaccaattg atctttatgc attgtttgcc agcttttcat gatcgaacaa
     8161 ctcaggtggg agaagaaatc tatgaaaaat atggcttaaa tgagatggaa gtaacttatg
     8221 aggtctttaa ttcaaagtat gcttggcaat ttacagaagc tgaaaatcga ttgcattcaa
     8281 ttaaagcagt gatggcggct actttaggaa atttatttat tccgattgcc tgtggcggtg
     8341 gtggcatccc tgttattgtg aaagatgggc atctcagagg tgttgccggc gtaattgata
     8401 aagatttttc cgctgctaaa atggcagaag atatcaacgc tgatgaatta gtaattctaa
     8461 caacggtgga tcatgcattt ttgaattatg gcaaagaaaa tcaacaagca attggtaaaa
     8521 taaaagttga acagctcaaa caatatctag cagcaggtta tttcgcagct gggagtatga
     8581 agcctaagat agaagctgca attgaatttg tagaaaaaac aggtaattta gcaattatca
     8641 cctctttgag caatgccaat aaactagcag acggagtcgg cacaatcgtt tataattaac
     8701 agggtgataa aaatgaatat ttttaatgaa ggaaaaaagc aggatattgc ccaagtttta
     8761 gcagctaaag ataggcgagt agctgtacaa cataagattt ttaataagta tcctaatcaa
     8821 actctagtcg acattaagat gaatatccca ggaccaatca agaataatcg ctatttaact
     8881 aaaatgttta tgtttggtat caataagctg gaaaatgctt ggactaacct aggttatcat
     8941 tttaaattgg tgacacagct taatgatgat agtggctgtg aaaacttcta tgtattatct
     9001 ttgtcaattg aaaaagtaaa gcgctcaaca attgattttg aagatcagac atcattggga
     9061 cgtctctttg atgcagacgt gttggtaaaa aataaacaag ctgcaatttc acgcagagat
     9121 ttgggcaggc agccacgtaa gtgcttttta tgtgatcgcc cttctaaaga atgtgctcgc
     9181 agccggagac attcagtgga acagatgcag gcatttatct ctcagcttta tcaagaatac
     9241 gttgcgtaaa ataaaccggg attttatgat tccggtttat ttttatgaaa aatctagtta
     9301 aaaattaaaa aaatgaacta aaatagtaat gaataaattt atagatgtac gtataggaat
     9361 aagcatgaaa ttaaagaaaa ataagaataa tttaaagcaa attacggcat taattcaata
     9421 tgcatttttg aaaaataatg atttgactaa agatgaaaat tttatgagtc gttatgatca
     9481 tagtacaggt tatggctatt ttgataagga aaaattagct agctatatta tggttaatcg
     9541 atttaaaagt gatgtttttg ggcatcattt accgatggct ggaataggtt atgtagcttc
     9601 atgtcctgag tatcgtggcc aaggtcatat ttcccaatta atgaaagaaa ttttgcatga
     9661 cttacatagg caagatattc cgtttgctaa cctggcacca ttttcggaga gcttttatcg
     9721 ccagtacggg tttagcaata gtatttatca aaaagaatat cgctttgatg gaagcgcatt
     9781 gcgtagtttt aaattaccac gttctggtca tatagtgcgt ggcaagtggg acaatttagc
     9841 tgttcaaaat ggtgtgattc aactttatga acgtcaactg catactaatg atgaacgtaa
     9901 cacggttgta cgtgaggcat ggtggtggaa tagacttgat tcttattatc atcaccgcaa
     9961 tgtagccgtt tattttgacg cggatgagcg gccaatgagt tacttgattt atcgcattag
    10021 agacaatact tttttagctg atgaaatgta cgcaattacg ccgcagggat tactgagtat
    10081 gtttggtttt atgggttcgc acgcgggcag tgttaagcaa tttaaaatga gtgtaccaga
    10141 gaaatcgtta cgagctgaac tttttcctga acaaaacgaa ctccaagttg atttgcgtcc
    10201 ttatatgatg agtcgaatta ttgattttga aaaagttttg gcttgtatgc ggccaatgca
    10261 agaaggtgat tttaatctgg aagtcaatag cgatgaacag tgtccttgga atattggagt
    10321 ttggcaatta agtaatcatg gacgtaaggt agcggtagaa cgtaaggaag atgcattggt
    10381 tgatttttcg ggatcaatta ccgcgtggac ccaggtgcta ttaggtagac taaccatgaa
    10441 tgctgctgtt aaactaggat taattacaga ttaccgcatc aaaaaattag atttcgttaa
    10501 aggcgatgta tcattttatg attattttta gttgtgaggt taaaaaatga gtaaagaaaa
    10561 gaaactcaat ttaataaaat tatttggcat tgtagttagt ggtttgaatt tgatcttttt
    10621 tgccttgatg gcacttaata agcatgaaga tactaaggat aaaagaagag tagcagaaga
    10681 aggacacgca ccgctggatg aaaaataaaa tgacggaatt aaagattgca tattttgacc
    10741 aattaggtcg taaggaatta gatcaggcag tgcagcattt tgtgttaaaa catcctaatg
    10801 tagatgtaaa actacttgcg actagtcatg atggtgcttt tgcaaaactg aatgaagatg
    10861 aagcagacat agcaatcaat gatttgcgtg acgagaatct taactttgat gaaacagaat
    10921 tgactcaagc tggtgtaatg gcaattttgc ccaagggaat gtatcctaat ggcattcaaa
    10981 tgattgaaaa agacgagctc aatgatatga cttgttttat tgtggctaaa cctgaagaag
    11041 aggttagtga gctacattta tttaaagatt tgtatcaaat tggcagtcaa ttcatcgctt
    11101 ctaactcggt tgaagaagca gcactgttgg tcgcctctgg gtctggctat tttattttaa
    11161 atgagaatac ggctaggtta attaatactg cagatttgca gccacttttc ttgcttgatc
    11221 atggtcagtt aataaagcaa aagataatgg ctttttataa gtcaaattca gcgttaagta
    11281 gtgagtttat aaaactattg cagcaagaat attaatctgt aaagttaaaa atatcttgtc
    11341 taagtactat aagatactgt aaaatatatt atgaaagcgg attcatatat tttacattct
    11401 ggagatgatt tttatgctaa aaagaacttt gttaccttta acatcaatgg tacttgtttt
    11461 aggattaact ggtttggcta gtcaagttga gactgttgat gcttcaactt atggtaatgg
    11521 tgtacaggtt actattccaa aaaagatgca gggtacttgg tactcttatg atcgtaatgc
    11581 acataatggc acaaagatca cctttactga acatactgtt aatggcaaac caatatttac
    11641 ccaggaggct tcgacaatta gtgattactt caatggtaga attgctaacc agaagaactt
    11701 tgataaggta acgcaaaact ggatgtctgg taaaactacc aaaatgaaga atgatacatt
    11761 ctatgagatt gatccgtgga ttacttttga aaattggagt ctttatcgag tggtaccaca
    11821 aaccattaat ggtaaaaagc ataacgtgct ggtttattct agtagatatg atggtggtaa
    11881 ctacttcaga agcaagaaat tagctaaaaa aatgaaggac tacaagttta agaaagttaa
    11941 ttacacgtta tagttttgtg acatccctta actaagggat gttttttact aatagacgcg
    12001 gtaaaattta gtataatagt gacaaaatta attcttggag gagaagttat gaaattaaaa
    12061 caaacaccaa ttttgcgttt atataaacta gaaactaata aagaggatca tgcaaagttc
    12121 gttaaggcag ggcaacataa tatgcttact tctcaagaaa acgaaccagg cacattgttt
    12181 atgcagacaa gtcatgacga agaaactact aattttgtag tagaatgcta tcaagacgaa
    12241 gcaagttatg atactcatgc taattcaaag caatttaagg attttactga cgttgctaaa
    12301 gatattttaa ctagtcgagt aaaggtagaa ttgttttcgg aatttatttt tacaaaggca
    12361 gaaaaactag cagttaccgg atcaaatgat tatgttattt atctaactga aattggtgtt
    12421 tctttaggta agggcgatga gtttgctcat gctgtaatga aagaaatgaa aacggcagtc
    12481 gaagaagaaa aagatatttt ggcaatgatt gcaggaactg ttgccgatca accaaatgaa
    12541 tggttagcta ttgaagttta tcgtaataat gaagcttaca agcagcactt ggaaactaag
    12601 aacttcaaag agtatttgaa taatacaaaa tattgtgttg aaagtaagag tttacgtaag
    12661 ttgcaaccag atgtaattgt tgaccaaggt gcaattttct accaaccata aagaataaga
    12721 cgaaaagaag accaggctat gtggagtaca taacctggtc tttctagtta gaggggaaaa
    12781 agatttatta acatatatta ttctggtttt tagtggcgat gttttacctt tgctactgct
    12841 ggtttattaa ttaatactga gctgatggcc attaaaccaa gcgttaaaaa tgatccacca
    12901 attaagagta gtttaatcaa ggttctcatt cctttcatct taattgatct tataatagcg
    12961 aaataatatt aagaatttat atgtaaaacc taatggatta gttaagaaaa taaaactaga
    13021 aaaaaggctg gttagcacgt aaaatagaaa tagagtcaaa gtctagtgca actgcgcata
    13081 aaataaagca gtatcgatgg gatgctgctt gttttggtta aaaaatagag aatatgcttg
    13141 tagccctttt cgtaaatagc gttaatgttg taaaatggaa agtgcattaa gtttattaat
    13201 gagaaaattg atgtattatt gcaaaaaagg ccgtaatggc cctttttgtt gtgaaaaaac
    13261 taaaagaata taggattgga aatgccagga atagtagagc aaacattatt agaacaacaa
    13321 aatattgatt taaatgaaat ggtaacaatg aatcaaatga ttgatcaatt gttgcctaat
    13381 gcaagtaaag aattacaaca aaaactaaag attaaaattt ataactttgt gcgtacacgt
    13441 aaacaaccaa gtattactgt gcgaagaaga aaatatttta agccggctgt tgctaaatta
    13501 attattggta atgtacaaga ttacgcagat gcaattgaac gtcgtgctaa ggaagcccca
    13561 gctaaagagg atgctactga taagaagcca gcttctaaat ctaagcgggt taggacaatt
    13621 actaagcgta agattttagc taaagttata aagaatgata agattgataa atctattcaa
    13681 aagaaattag aagataagat tgcttcaatt gtgaagacca actttattaa gccagttaac
    13741 aagcggggaa gtttttcggt tgaagatggt gaaaaagtta tagctgaact tagtcctttt
    13801 tatcaaaata tcaagattga tcaaaagtat cgcaagaatg ctgaaaaagc ggctgaaaat
    13861 aaggaaacag aaactaaaga aaagcctgag caacattcta aggatcagaa tgaaagtcgt
    13921 gaaggtcaat ctaaggactt tgagcgtaag aataatcaga agaatagcaa taatcgaaat
    13981 aataatcaaa cgcaaaatca acgtaagcga caaaataagc atccttttga gatcagaaga
    14041 gaaaataata accgctcacg taataatcag tctaaccgcc gctataataa tcgaaataat
    14101 tatgataatc gaaataatta tgaatttgat gaagctagcg gtttgcgtga acgctacaat
    14161 acagtaatca gaaattacaa tcaactggag caaagatata atgctttgca agataaatat
    14221 aatcaggctt tagatgataa agctagattg atcgaagaaa tgggcaagaa gaacgaagac
    14281 ttacgtcgtg tattgatcga cgttttgcga aaaatgtagt ttttggtaaa gaaagagact
    14341 agtagtcaat ttgaattgat tactagtctt attttatgtt tatgaaatat gatttagctt
    14401 aaaaattaaa aaaaatatgt gtaaaaaatt atttttgtga gactgtaaaa tagtttgtgt
    14461 aaggatgaat gattccttaa atttatttct ttaaacatta gaaaaaggag ttcctttctc
    14521 gtatgattgg tttgaacaaa aaaaacacat acagaaagaa gaactccttc atgaatgatt
    14581 ttaccaaaga ttttgctcaa gctctattca atccagacaa aataaatgat ttattgcgca
    14641 aagagctaca acaggctgtt aataacttgt tagaagctga attgactgcc tttctgggct
    14701 atgatcccta tgccagaaat ggctggaata ctggcaattc tagaaatgga gcttatt
//
