LOCUS       c00053_gnlPro..        14352 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BGPMHAPK_53.
ACCESSION   c00053_gnlPro..
VERSION     c00053_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 05:12:04
            Original ID  :: gnl|Prokka|BGPMHAPK_53
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14352
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1020)
                     /locus_tag="ctg53_1"
                     /transl_table=11
                     /translation="MTMRSLGLSIYPDHTNFEDNTKYLELGHKYGFTRIFMSMLEVQGS
                     PEETPAKYKKIIDYGNKLGYQTFLDVSPQLFKKLEIDYSDLKFFADIGAAGIRLDEAFD
                     GATEAMLSYNPYGLIIELNMSNNADYLNNILSYQASQPFIYGCHNFYPQRGTALPYDFF
                     LDCSTRFKNFGIHSAAFVSSQVGKVGPWNVEDGLPTLEEDRDLPIEVQAMHLFASNMID
                     DVIIGNAYASEAELKALFELNRYQLKLHVNYVSDINEIEKTIVEKPQHFRRGDLTKAVI
                     RSTMQRVTYKDIPNPIHDNEVEFQRGDVIIGNDNFGHYKNELQIVLEPHKEPRDCKIVC
                     "
     protocluster    1..14352
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5584:8216]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5585..8216
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..14352
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14352
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             1296..1676
                     /locus_tag="ctg53_2"
                     /transl_table=11
                     /translation="MALAVFISATSAYLTMTVFARSFASFIAAHQWEVWLLILLPIVYG
                     VTFAFLTEAYSGHNVASATVFVIMAIIGTVTKKDLSRIGSYASAALIGLIVAMVINLFL
                     HNPIIDYIFSTIAVIIFTILTA"
     CDS             1946..2095
                     /locus_tag="ctg53_3"
                     /transl_table=11
                     /translation="MAIVALLTLVGEISVIPANLQNTSYRKKEGVSNMTGLKLLVISDQ
                     KYFM"
     CDS             2095..2193
                     /locus_tag="ctg53_4"
                     /transl_table=11
                     /translation="MRGHNYRMNRENAIFFKSKAAARAAGYRESKR"
     CDS             complement(2261..4534)
                     /locus_tag="ctg53_5"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGEVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNR"
     CDS             4663..5511
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg53_6"
                     /sec_met_domain="LysR_substrate (E-value: 1.8e-30,
                     bitscore: 96.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.5e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIDA
                     I"
     CDS             5585..6814
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_7"
                     /sec_met_domain="Amidinotransf (E-value: 7.7e-109,
                     bitscore: 354.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELPTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEIVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             6825..7229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_8"
                     /sec_met_domain="OTCace_N (E-value: 7e-38, bitscore: 120.4,
                     seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVN"
     CDS             7249..7578
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_9"
                     /sec_met_domain="OTCace (E-value: 9.7e-26, bitscore: 81.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLADFMTMKEKFGHLKGLTLAYVGDGRDNVADSLLVCGSMLGVNV
                     HIVTPKPLFTHPDVQKIAQNFAQDSGSKNLITDDIAQGVKGANVVYTDVWVSMGEMIGL
                     NELNY"
     CDS             7605..8216
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_10"
                     /sec_met_domain="OTCace (E-value: 1.6e-17, bitscore: 54.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 1.4e-21, bitscore:
                     67.5, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQMTGTPDDQLIFMHCLPAFHDRTTQVGEEIYEKYGLNEMEVTYE
                     VFNSKYAWQFTEAENRLHSIKAVMAATLGNLFIPIACGGGGIPVIVKDGHLRGVAGVID
                     KDFSAAKMAEDINADELVILTTVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGS
                     MKPKIEAAIEFVEKTGNLAIITSLSNANKLADGVGTIVYN"
     CDS             8230..8766
                     /locus_tag="ctg53_11"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDIKMNI
                     PGPIKNNRYLTKMFMFGINKLENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFEDQTSLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPSKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             8846..10048
                     /locus_tag="ctg53_12"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMKLKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASCPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTNDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     MSYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPE
                     QNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRK
                     VAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDY
                     F"
     CDS             10064..10225
                     /locus_tag="ctg53_13"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             10227..10832
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_14"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-13,
                     bitscore: 41.5, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASGSGYFILNENTARLINTADL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             10888..10998
                     /locus_tag="ctg53_15"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             10964..11470
                     /locus_tag="ctg53_16"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             11536..12228
                     /locus_tag="ctg53_17"
                     /transl_table=11
                     /translation="VTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFSEFIFTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(12327..12455)
                     /locus_tag="ctg53_18"
                     /transl_table=11
                     /translation="MKGMRTLIKLLLIGGSFLTLGLMAISSVLINKPAVAKVKHRH"
     CDS             12799..13836
                     /locus_tag="ctg53_19"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKKPA
                     SKSKRVRTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNYE
                     FDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLID
                     VLRKM"
     CDS             14088..14351
                     /locus_tag="ctg53_20"
                     /transl_table=11
                     /translation="MNDFTKDFAQALFNPDKINDLLRKELQQAVNNLLEAELTAFLGYD
                     PYARNGWNTGNSRNGAYFRKVDTQVSPIAVQVPRDRNGQFHQH"
ORIGIN
        1 acaaactatt ttacagtctc gcggttcttt atgcggttca aggacaattt gtaattcatt
       61 tttataatga ccaaaattat cattgccaat aataacgtca ccgcgttgaa attctacttc
      121 gttatcatgg ataggattag gaatatcttt ataggtaact cgctgcatag ttgagcgaat
      181 aaccgcctta gttaggtcac ctcggcggaa gtgttgtggc ttttcaacta ttgttttttc
      241 aatttcgtta atgtcagata cataatttac gtgtaatttt aactgatagc gatttaattc
      301 aaagagtgct ttaagttccg cttcactagc ataggcgttg ccaataatta catcatcaat
      361 catatttgaa gcaaataaat gcattgcttg tacttcgatt ggtaaatcgc ggtcttcttc
      421 taaagtaggg aggccatctt caacattcca aggaccaact ttgccaactt gactagagac
      481 aaaagcagca gagtgaatgc caaaattttt aaaacgtgta ctacaatcta agaagaaatc
      541 ataaggtaga gccgtgccgc gctgtggata aaaattatgg cagccataga tgaaaggttg
      601 gctggcttga taagataaaa tattgttgag gtagtcagca ttattactca tgttaagttc
      661 aataattagg ccataaggat tgtatgaaag catggcctct gttgcaccgt caaaagcttc
      721 atcaagccga ataccagctg caccgatatc tgcaaaaaat ttcagatctg aataatcaat
      781 ttctaatttc ttaaagagct gaggtgatac atcaagaaaa gtttggtagc ctaatttatt
      841 gccgtagtca ataatcttct tatatttagc tggagtttct tcagggctac cttgtacctc
      901 aagcatactc ataaaaatac gagtaaagcc gtatttatga cctagttcta agtatttcgt
      961 attatcttca aagttggtat gatctggata aatggacaga ccaagtgatc tcattgtcat
     1021 aaaagtacct ctttcttatt aatatgtcta taccaattag atcaagctta gcattatagg
     1081 tctagtccaa agcaagaaaa gcagtgaaat aatacgctca aaatatagta tgctgatagc
     1141 aattcgtctc gttacttttt cagtaaacca ggtgttatat taggtgtaca gagtatgttt
     1201 aaaaagaggg aaaatcaaga tggaaaattg tgatcaagag tctgagcgac gacaagtgga
     1261 tgcacttggg ttaaatcttt ttttgagtag aatatatggc cttggcggtt tttatttcag
     1321 ctaccagtgc ttatctaaca atgacggttt ttgctagatc atttgctagc tttattgcgg
     1381 ctcatcaatg ggaagtgtgg cttttaattt tactgccaat tgtttatggc gttacttttg
     1441 cttttcttac cgaggcttat agcggacaca atgttgcttc ggctactgtt tttgtcatta
     1501 tggcaattat cggaactgta actaaaaaag acctgagtcg aattggttct tatgcttccg
     1561 ctgctttaat cggcttaatt gtagcaatgg taattaattt gtttttacat aatcctataa
     1621 ttgattatat tttttcaact attgcggtca ttatttttac tatattgacg gcataggatg
     1681 ctcagcgcat gaagaatatt tatttacgct atggtgatga tatttcaact aatggactag
     1741 cagtgctggg tgcactgcag ttatatcttg actttgttaa cttgttttta caatttctag
     1801 atatttttag cgcaagtgaa agtaattaaa atttgacttt atgttaattc aaatgaaata
     1861 agcacaatct aatatataag cgtatgctac gaagatatag ttattattag gaaggttttt
     1921 aatgaaaaaa tgcaaaaatt tgttgatggc aattgttgca ttattaacgt tagttgggga
     1981 aattagtgtt atacctgcga atctacagaa tacatcttat cgtaaaaaag aaggcgtaag
     2041 caacatgaca ggactaaaat tgttggtaat aagcgatcaa aaatatttca tgtaatgcgt
     2101 ggacataatt accgaatgaa tcgcgaaaat gcaattttct ttaagagcaa agcagcggct
     2161 cgtgcggcgg gatatcgtga gtcaaaaagg taaacgaaaa gcacttccaa gaatgtaatt
     2221 tcttagaagc gcttttttaa tgcaaaattg aattaataat ctatctgttt ttcatcacag
     2281 gttggtaaat taagtcgatt attatggcag caataatcgc tacaattacg gtgattgcta
     2341 gattttgaat agaaatttgg accattgccc aaccacaaag agctaagata aaggtcaata
     2401 gaacatctgc aatttgaaca ctaccaacca acttggatgg gtaatcttgc caaaagtact
     2461 tacgagttct agtaatcaaa acaatcaaca ttgcgctaag aactaggtat acgtaaacca
     2521 tagtagaaac agcaccgtga ctccaaccgt gtgtgtttaa gaaccaaaca aacccaatac
     2581 cgattaaagt ccaaccagca gctagtgaaa aggcgatctt agcaagctta gccatattcc
     2641 agttttctgg cttataagta atgtgagtcc ggtcggtccc aatcatcatc gtaaccatat
     2701 tgttcataat ggtatagata accattgcat tcaaggccat tgggatgtag tcaaagaaaa
     2761 gatagccaaa agttaacagc atcgttaatt cagcagttct agcaagcttg gttagtgacc
     2821 aagtagtcat tctttggtat acgcgatgtc cagcgtctaa aattttaaca attgagccta
     2881 gaccatcgtc tagtaatacc attttacccg aacgcttagc tacgtcagca gcatttgaaa
     2941 ccgcgattcc tacttcagct tgttttaatg caggtgcgtc gttaactccg tcaccagtca
     3001 tccctacgat atagcctttt tcttggaaaa gctttaccat cttgagttta tcttctggta
     3061 aaacatcagc aataccggcc aaatcattaa tatcagtatt ttcattgaaa tcgtgaatcg
     3121 aaattacttc accagttaaa tcaacttgtt ctgccactgc agcagcggtc ttttgattgt
     3181 caccagttaa cataattggg cgaacgccac gtttcttgag ttcagccaaa gctgctttag
     3241 agtctgttct aactttatct tgtaagatga agacaccagc taacttatcg tcaatcaaga
     3301 ctgccactga gcgtcctgcc ttgaaattaa ttccagaaat ttcttcatcg gcatgtttat
     3361 cgatcaagga taattgctta aatgaaccaa gctttacatt atgtccagca acatcagcca
     3421 tagaataacc agtgtcagaa gtaaatggag taaagttttc agcattcatg actggaatgt
     3481 tattttctac taagtattca tcgattgctg tatcgataat accagcatta cgtttatcag
     3541 ttgcggctcc agctaaagca agcacgtctt tatcaggcaa gtcacttaga tcagtccaag
     3601 cggctacggc agttttgttt tccgtaattg ttccagtctt atcaagtaaa agcaagttca
     3661 agttagctgc gtcctgaatt ccagttaggt cagaagtcag gactccttct ttacttaagc
     3721 gggttgcttc aaatgagttg gataaagcaa aagttgatgg cattgctaca ggaattgaag
     3781 caataaacat cattgccagg aatggcaaca tattaataaa ggtattgaaa ttaccgcctt
     3841 tgaagaagga ggcgataata ataactaagg ttaaaacacc atctagtaag caaaggtagt
     3901 agataatctt agtcaaaagt tgttgtaagt gaccaggagc agcggaattg ttgatcaaat
     3961 taatcgtctt accgcttcta gaatctttac ctgtagcagt aacaacagct aggccatcac
     4021 cttcaacaac tgtagtaccg gcaaaggcgg tgtcatcaat tgctttctta actggtttag
     4081 attcacctgt aattgagctt tcatcacaag ctaagttacc gtcaacaatt ttaacatctg
     4141 ctgcgagtac gtccccgcgt ttaagtgaga ttaaatcgcc tttaactagt tgtttagaat
     4201 caagtttgat ccacttgcca tcgcgttcaa ctgatacagt aggagtcaac ttgtgtgaaa
     4261 tattatttaa aactcgtctt gattgctttt tcttagatgc accgttaaat gcagcaaata
     4321 aaagcatcaa caacacgaat aatgattgga cccatttgcc caagatacat tctagaatta
     4381 aagcagcttc tagaatccaa gcggataggt tccataactt agacaagaat tctttaaaga
     4441 aattatattc aggctctggt acttcattta agccatcttc ttttaagcgc ttgtctgctt
     4501 cggcttgagt taagccgtga aatttatcag acattatttt ccctccaaat ctaccttaat
     4561 aaggtagcac agatattgct atgaataaaa tactaaaata caatataaga tattaaatat
     4621 tttaatatca ctatcaattg aaataaaaaa aggataaata atatgaatct aaaacagtta
     4681 cgttattttc tagttgtagc agaagaaaag cagattacag cagctgctaa gcgcttgtat
     4741 attgcacagc caccattaag ctatcaatta aaacaattag agaaagagtt gggcgcgcaa
     4801 ttatttaaaa gaacggcaca tggtattgag ctaactgatg tgggacaaat ttttcaaagc
     4861 tatgccaatg aaattatttc tctagctcaa aatgctgaaa accaagtaca taagactatt
     4921 tccggtgaat tgggaacgat tgcaattgga atggcatctt cctcaacggg cttgatacca
     4981 atgaattctt ttaatgaatt acgaaaatat tatccggaaa tttcttttga tatttatgaa
     5041 gataatactt atggcatcct ggataaatta gaaaaaaaga caatcgatct aggcattgta
     5101 cgaacgcctt acaaccagac aggtttaaat actaagactt taacaactga aaaaatgatg
     5161 gctattagtg tagacccaga ttttcagcaa aaaaaagaat tacgcattaa agatctagca
     5221 gatcagccgt tgattattta tcgccgcttt gaggatattt ttaatcaaac ttttgcacat
     5281 catgggctta agccatttta tgcggttaag tgtgatgatt cacggacagc aattacttgg
     5341 gctaagagaa aaatgggagt agcgctagta ccagaatcaa ttgcgacaac ttatgcccaa
     5401 gaaaatatga tcgcaattaa acatgctaat tggataacac atttgcagct ggtttggcgt
     5461 aaagatcatc aagttacacc tttaatgaaa aaaatcattg atgcaatatg ataatactgt
     5521 aacttttgcc taattgatcc ataatcaatg taaacggata caataattaa tagaaggcgg
     5581 ttgaatgtcg agtccgattc atgtttattc agaaattggt aagttaaaaa cggtgatgtt
     5641 acatcgaccg ggaaaagaac tagaaaatct agccccagat attttgcatc gaatgttaat
     5701 tgacgatatt ccttatctga agattgccca agaagaacat gatgcttttg cgcatgtatt
     5761 gaggcagcag gggatcaaag tattatatct tgaggattta ttagcagaat ctttaacaga
     5821 tgagaaagtt cgtcgggcat tcttagatca gttactggat gaatcaagta ttaaaaaaca
     5881 ggatcctttg catcaattat tgctgaacta tctccaagaa ttgccaacta aggaaatggt
     5941 aaaaacggtg attgctggaa ttagaaaaag tgcgattcat aattctaccc catctttagc
     6001 agatttggct gaggacccag attacccttt ttatcttgat ccaatgccaa atgtatattt
     6061 tactcgagat caacaggctg caattggttc agggatgacc attaaccgga tgactttcag
     6121 agctagacga cgtgaatcat tatttatgga aacaattttg aaaaatcatc ctgatttcaa
     6181 gaacgcaact attccagttt ggcgtgaccg ttatcatcat ggtcgccttg agggcgggga
     6241 tgaactagtt ctaaataacc atgtgttagc tgtaggtatt tcacaacgca cttctgcaac
     6301 tgcaattact gacttagctc ataatttatt tgatcattca agttatgata cgattttagc
     6361 gattaagatt ccgcacaatc atgctatgat gcaccttgat acagttttta caatgattaa
     6421 ttataatcaa tttacggttc atccctttat tttagataaa gccggcaaaa ttgatattta
     6481 tgttctacag cccgatgatc acaacggtgt aaaaatcaca gaaaagaatg atttggtgca
     6541 ggttttgaaa gaaaacttgc atttaagcga attggattta attccaactg gcggtggtga
     6601 tccaattgcc gcaccacgtg agcaatggaa tgacggctca aataccttgg caattgcacc
     6661 aggtgaaatc gttacttatg atcgtaatta tgtatccaat gatttgttaa gaaaacatgg
     6721 catcatcgtt catgagattc ggtctagtga actctcacgt ggtcgtggcg gtcctagatg
     6781 tatgtcgtgt ccgttgattc gtgaagattt ataagaggca aaaaatgaaa tatttacaaa
     6841 atgtttttca aggtagaagt tttctcgatt gtaaagacta tactccagct gaaatttcat
     6901 atttaattga ttttgcatta catttaaaag aacttaaaaa agagcatatc ccacatgaat
     6961 atctgaaagg taaaaatatt gcactacttt ttgaaaaagc ctcaactagg acgcgatctg
     7021 cttttgtagt agcttgtaat gatttaggtg ctcatccaga atatctaggc gcaagcgaga
     7081 tccacttagg taaaaaagaa agcgtcaagg atacggctaa agtcctaggc tcaatgtatg
     7141 atggaattga atatcgcggt tttgctcaag aagatgtaga agagctggct aaatattctg
     7201 gcgttcctgt ttggaaatgg gttaactgat aaatggcatc ctactcagat gttggcagat
     7261 tttatgacca tgaaagaaaa gtttggtcat ttgaagggct taactttagc ttatgtgggt
     7321 gatggccgcg ataatgttgc cgacagtctt ttagtttgtg gctcaatgtt aggtgttaat
     7381 gtacatattg ttacacccaa gcctttgttt acacatcctg atgtacaaaa aattgctcaa
     7441 aattttgccc aagattcagg ttcaaaaaat ttgatcacag atgatattgc tcagggcgtt
     7501 aaaggagcca atgttgttta taccgatgtt tgggtttcga tgggtgaaat gattggtctg
     7561 aacgaattaa attattaaag ccatatacgg tcacaatgaa aatgatgcaa atgactggta
     7621 caccagatga ccaattgatc tttatgcatt gtttgccagc ttttcatgat cgaacaactc
     7681 aggtgggaga agaaatctat gaaaaatatg gcttaaatga gatggaagta acttatgagg
     7741 tctttaattc aaagtatgct tggcaattta cagaagctga aaatcgattg cattcaatta
     7801 aagcagtgat ggcggctact ttaggaaatt tatttattcc gattgcctgt ggcggtggtg
     7861 gcatccctgt tattgtgaaa gatgggcatc tcagaggtgt tgccggcgta attgataaag
     7921 atttttccgc tgctaaaatg gcagaagata tcaacgctga tgaattagta attctaacaa
     7981 cggtggatca tgcatttttg aattatggca aagaaaatca acaagcaatt ggtaaaataa
     8041 aagttgaaca gctcaaacaa tatctagcag caggttattt cgcagctggg agtatgaagc
     8101 ctaagataga agctgcaatt gaatttgtag aaaaaacagg taatttagca attatcacct
     8161 ctttgagcaa tgccaataaa ctagcagacg gagtcggcac aatcgtttat aattaacagg
     8221 gtgataaaaa tgaatatttt taatgaagga aaaaagcagg atattgccca agttttagca
     8281 gctaaagata ggcgagtagc tgtacaacat aagattttta ataagtatcc taatcaaact
     8341 ctagtcgaca ttaagatgaa tatcccagga ccaatcaaga ataatcgcta tttaactaaa
     8401 atgtttatgt ttggtatcaa taagctggaa aatgcttgga ctaacctagg ttatcatttt
     8461 aaattggtga cacagcttaa tgatgatagt ggctgtgaaa acttctatgt attatctttg
     8521 tcaattgaaa aagtaaagcg ctcaacaatt gattttgaag atcagacatc attgggacgt
     8581 ctctttgatg cagacgtgtt ggtaaaaaat aaacaagctg caatttcacg cagagatttg
     8641 ggcaggcagc cacgtaagtg ctttttatgt gatcgccctt ctaaagaatg tgctcgcagc
     8701 cggagacatt cagtggaaca gatgcaggca tttatctctc agctttatca agaatacgtt
     8761 gcgtaaaata aaccgggatt ttatgattcc ggtttatttt tatgaaaaat ctagttaaaa
     8821 attaaaaaaa tgaactaaaa tagtaatgaa taaatttata gatgtacgta taggaataag
     8881 catgaaatta aagaaaaata agaataattt aaagcaaatt acggcattaa ttcaatatgc
     8941 atttttgaaa aataatgatt tgactaaaga tgaaaatttt atgagtcgtt atgatcatag
     9001 tacaggttat ggctattttg ataaggaaaa attagctagc tatattatgg ttaatcgatt
     9061 taaaagtgat gtttttgggc atcatttacc gatggctgga ataggttatg tagcttcatg
     9121 tcctgagtat cgtggccaag gtcatatttc ccaattaatg aaagaaattt tgcatgactt
     9181 acataggcaa gatattccgt ttgctaacct ggcaccattt tcggagagct tttatcgcca
     9241 gtacgggttt agcaatagta tttatcaaaa agaatatcgc tttgatggaa gcgcattgcg
     9301 tagttttaaa ttaccacgtt ctggtcatat agtgcgtggc aagtgggaca atttagctgt
     9361 tcaaaatggt gtgattcaac tttatgaacg tcaactgcat actaatgatg aacgtaacac
     9421 ggttgtacgt gaggcatggt ggtggaatag acttgattct tattatcatc accgcaatgt
     9481 agccgtttat tttgacgcgg atgagcggcc aatgagttac ttgatttatc gcattagaga
     9541 caatactttt ttagctgatg aaatgtacgc aattacgccg cagggattac tgagtatgtt
     9601 tggttttatg ggttcgcacg cgggcagtgt taagcaattt aaaatgagtg taccagagaa
     9661 atcgttacga gctgaacttt ttcctgaaca aaacgaactc caagttgatt tgcgtcctta
     9721 tatgatgagt cgaattattg attttgaaaa agttttggct tgtatgcggc caatgcaaga
     9781 aggtgatttt aatctggaag tcaatagcga tgaacagtgt ccttggaata ttggagtttg
     9841 gcaattaagt aatcatggac gtaaggtagc ggtagaacgt aaggaagatg cattggttga
     9901 tttttcggga tcaattaccg cgtggaccca ggtgctatta ggtagactaa ccatgaatgc
     9961 tgctgttaaa ctaggattaa ttacagatta ccgcatcaaa aaattagatt tcgttaaagg
    10021 cgatgtatca ttttatgatt atttttagtt gtgaggttaa aaaatgagta aagaaaagaa
    10081 actcaattta ataaaattat ttggcattgt agttagtggt ttgaatttga tcttttttgc
    10141 cttgatggca cttaataagc atgaagatac taaggataaa agaagagtag cagaagaagg
    10201 acacgcaccg ctggatgaaa aataaaatga cggaattaaa gattgcatat tttgaccaat
    10261 taggtcgtaa ggaattagat caggcagtgc agcattttgt gttaaaacat cctaatgtag
    10321 atgtaaaact acttgcgact agtcatgatg gtgcttttgc aaaactgaat gaagatgaag
    10381 cagacatagc aatcaatgat ttgcgtgacg agaatcttaa ctttgatgaa acagaattga
    10441 ctcaagctgg tgtaatggca attttgccca agggaatgta tcctaatggc attcaaatga
    10501 ttgaaaaaga cgagctcaat gatatgactt gttttattgt ggctaaacct gaagaagagg
    10561 ttagtgagct acatttattt aaagatttgt atcaaattgg cagtcaattc atcgcttcta
    10621 actcggttga agaagcagca ctgttggtcg cctctgggtc tggctatttt attttaaatg
    10681 agaatacggc taggttaatt aatactgcag atttgcagcc acttttcttg cttgatcatg
    10741 gtcagttaat aaagcaaaag ataatggctt tttataagtc aaattcagcg ttaagtagtg
    10801 agtttataaa actattgcag caagaatatt aatctgtaaa gttaaaaata tcttgtctaa
    10861 gtactataag atactgtaaa atatattatg aaagcggatt catatatttt acattctgga
    10921 gatgattttt atgctaaaaa gaactttgtt acctttaaca tcaatggtac ttgttttagg
    10981 attaactggt ttggctagtc aagttgagac tgttgatgct tcaacttatg gtaatggtgt
    11041 acaggttact attccaaaaa agatgcaggg tacttggtac tcttatgatc gtaatgcaca
    11101 taatggcaca aagatcacct ttactgaaca tactgttaat ggcaaaccaa tatttaccca
    11161 ggaggcttcg acaattagtg attacttcaa tggtagaatt gctaaccaga agaactttga
    11221 taaggtaacg caaaactgga tgtctggtaa aactaccaaa atgaagaatg atacattcta
    11281 tgagattgat ccgtggatta cttttgaaaa ttggagtctt tatcgagtgg taccacaaac
    11341 cattaatggt aaaaagcata acgtgctggt ttattctagt agatatgatg gtggtaacta
    11401 cttcagaagc aagaaattag ctaaaaaaat gaaggactac aagtttaaga aagttaatta
    11461 cacgttatag ttttgtgaca tcccttaact aagggatgtt ttttactaat agacgcggta
    11521 aaatttagta taatagtgac aaaattaatt cttggaggag aagttatgaa attaaaacaa
    11581 acaccaattt tgcgtttata taaactagaa actaataaag aggatcatgc aaagttcgtt
    11641 aaggcagggc aacataatat gcttacttct caagaaaacg aaccaggcac attgtttatg
    11701 cagacaagtc atgacgaaga aactactaat tttgtagtag aatgctatca agacgaagca
    11761 agttatgata ctcatgctaa ttcaaagcaa tttaaggatt ttactgacgt tgctaaagat
    11821 attttaacta gtcgagtaaa ggtagaattg ttttcggaat ttatttttac aaaggcagaa
    11881 aaactagcag ttaccggatc aaatgattat gttatttatc taactgaaat tggtgtttct
    11941 ttaggtaagg gcgatgagtt tgctcatgct gtaatgaaag aaatgaaaac ggcagtcgaa
    12001 gaagaaaaag atattttggc aatgattgca ggaactgttg ccgatcaacc aaatgaatgg
    12061 ttagctattg aagtttatcg taataatgaa gcttacaagc agcacttgga aactaagaac
    12121 ttcaaagagt atttgaataa tacaaaatat tgtgttgaaa gtaagagttt acgtaagttg
    12181 caaccagatg taattgttga ccaaggtgca attttctacc aaccataaag aataagacga
    12241 aaagaagacc aggctatgtg gagtacataa cctggtcttt ctagttagag gggaaaaaga
    12301 tttattaaca tatattattc tggtttttag tggcgatgtt ttacctttgc tactgctggt
    12361 ttattaatta atactgagct gatggccatt aaaccaagcg ttaaaaatga tccaccaatt
    12421 aagagtagtt taatcaaggt tctcattcct ttcatcttaa ttgatcttat aatagcgaaa
    12481 taatattaag aatttatatg taaaacctaa tggattagtt aagaaaataa aactagaaaa
    12541 aaggctggtt agcacgtaaa atagaaatag agtcaaagtc tagtgcaact gcgcataaaa
    12601 taaagcagta tcgatgggat gctgcttgtt ttggttaaaa aatagagaat atgcttgtag
    12661 cccttttcgt aaatagcgtt aatgttgtaa aatggaaagt gcattaagtt tattaatgag
    12721 aaaattgatg tattattgca aaaaaggccg taatggccct ttttgttgtg aaaaaactaa
    12781 aagaatatag gattggaaat gccaggaata gtagagcaaa cattattaga acaacaaaat
    12841 attgatttaa atgaaatggt aacaatgaat caaatgattg atcaattgtt gcctaatgca
    12901 agtaaagaat tacaacaaaa actaaagatt aaaatttata actttgtgcg tacacgtaaa
    12961 caaccaagta ttactgtgcg aagaagaaaa tattttaagc cggctgttgc taaattaatt
    13021 attggtaatg tacaagatta cgcagatgca attgaacgtc gtgctaagga agccccagct
    13081 aaagaggatg ctactgataa gaagccagct tctaaatcta agcgggttag gacaattact
    13141 aagcgtaaga ttttagctaa agttataaag aatgataaga ttgataaatc tattcaaaag
    13201 aaattagaag ataagattgc ttcaattgtg aagaccaact ttattaagcc agttaacaag
    13261 cggggaagtt tttcggttga agatggtgaa aaagttatag ctgaacttag tcctttttat
    13321 caaaatatca agattgatca aaagtatcgc aagaatgctg aaaaagcggc tgaaaataag
    13381 gaaacagaaa ctaaagaaaa gcctgagcaa cattctaagg atcagaatga aagtcgtgaa
    13441 ggtcaatcta aggactttga gcgtaagaat aatcagaaga atagcaataa tcgaaataat
    13501 aatcaaacgc aaaatcaacg taagcgacaa aataagcatc cttttgagat cagaagagaa
    13561 aataataacc gctcacgtaa taatcagtct aaccgccgct ataataatcg aaataattat
    13621 gataatcgaa ataattatga atttgatgaa gctagcggtt tgcgtgaacg ctacaataca
    13681 gtaatcagaa attacaatca actggagcaa agatataatg ctttgcaaga taaatataat
    13741 caggctttag atgataaagc tagattgatc gaagaaatgg gcaagaagaa cgaagactta
    13801 cgtcgtgtat tgatcgacgt tttgcgaaaa atgtagtttt tggtaaagaa agagactagt
    13861 agtcaatttg aattgattac tagtcttatt ttatgtttat gaaatatgat ttagcttaaa
    13921 aattaaaaaa aatatgtgta aaaaattatt tttgtgagac tgtaaaatag tttgtgtaag
    13981 gatgaatgat tccttaaatt tatttcttta aacattagaa aaaggagttc ctttctcgta
    14041 tgattggttt gaacaaaaaa aacacataca gaaagaagaa ctccttcatg aatgatttta
    14101 ccaaagattt tgctcaagct ctattcaatc cagacaaaat aaatgattta ttgcgcaaag
    14161 agctacaaca ggctgttaat aacttgttag aagctgaatt gactgccttt ctgggctatg
    14221 atccctatgc cagaaatggc tggaatactg gcaattctag aaatggtgct tatttccgca
    14281 aagttgatac gcaagttagc ccaattgcag tgcaagtgcc tcgcgatcgc aacggacaat
    14341 ttcatcagca ca
//
