LOCUS       c00060_gnlPro..        14740 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAHONNJH_60.
ACCESSION   c00060_gnlPro..
VERSION     c00060_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 05:28:12
            Original ID  :: gnl|Prokka|NAHONNJH_60
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14740
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..348)
                     /locus_tag="ctg60_1"
                     /transl_table=11
                     /translation="MNDFTKDFAQALFNPDKINDLLRKELQQAVNNLLEAELTAFLGYD
                     PYARNGWNTGNSRNGAYFRKVDTQFGPIEVQVPRDRNGQFHQHTLPDSKQQSDIMVRLI
                     INTSSKGETTRE"
     protocluster    1..14740
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6043:8675]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6044..8675
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..14740
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14740
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(424..1479)
                     /locus_tag="ctg60_2"
                     /transl_table=11
                     /translation="MTMRSLGLSIYPDHTNFEDNTKYLELGHKYGFTRIFMSMLEVQGS
                     PEETPAKYKKIIDYGNKLGYQTFLDVSPQLFKKLEIDYSDLKFFADIGAAGIRLDEAFD
                     GATEAMLSYNPYGLIIELNMSNNADYLNNILSYQASQPFIYGCHNFYPQRGTALPYDFF
                     LDCSTRFKNFGIHSAAFVSSQVGKVGPWNVEDGLPTLEEDRDLPIEVQAMHLFASNMID
                     DVIIGNAYASEAELKALFELNRYQLKLHVNYVSDINEIEKTIVEKPQHFRRGDLTKAVI
                     RSTMQRVTYKDIPNPIHDNEVEFQRGDVIIGNDNFGHYKNELQIVLEPHKEPRDCKIVC
                     VRMNDSLNLFL"
     CDS             1755..2135
                     /locus_tag="ctg60_3"
                     /transl_table=11
                     /translation="MALAVFISATSAYLTMTVFARSFASFIAAHQWEVWLLILLPIVYG
                     VTFAFLTEAYSGHNVASATVFVIMAIIGTVTKKDLSRIGSYASAALIGLIVAMVINLFL
                     HNPIIDYIFSTIAVIIFTILTA"
     CDS             2405..2554
                     /locus_tag="ctg60_4"
                     /transl_table=11
                     /translation="MAIVALLTLVGEISVIPANLQNTSYRKKEGVSNMTGLKLLVISDQ
                     KYFM"
     CDS             2554..2652
                     /locus_tag="ctg60_5"
                     /transl_table=11
                     /translation="MRGHNYRMNRENAIFFKSKAAARAAGYRESKR"
     CDS             complement(2720..4993)
                     /locus_tag="ctg60_6"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGEVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAADVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGWTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNR"
     CDS             5122..5970
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg60_7"
                     /sec_met_domain="LysR_substrate (E-value: 1.9e-30,
                     bitscore: 96.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.6e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIDA
                     I"
     CDS             6044..7273
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_8"
                     /sec_met_domain="Amidinotransf (E-value: 8.1e-109,
                     bitscore: 354.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELPTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEIVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             7284..7688
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_9"
                     /sec_met_domain="OTCace_N (E-value: 7.3e-38, bitscore:
                     120.4, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVN"
     CDS             7708..8037
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_10"
                     /sec_met_domain="OTCace (E-value: 1e-25, bitscore: 81.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLADFMTMKEKFGHLKGLTLAYVGDGRDNVADSLLVCGSMLGVNV
                     HIVTPKPLFTHPDVQKIAQNFAQDSGSKNLITDDIAQGVKGANVVYTDVWVSMGEMIGL
                     NELNY"
     CDS             8064..8675
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_11"
                     /sec_met_domain="OTCace (E-value: 1.7e-17, bitscore: 54.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 1.5e-21, bitscore:
                     67.5, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQMTGTPDDQLIFMHCLPAFHDRTTQVGEEIYEKYGLNEMEVTYE
                     VFNSKYAWQFTEAENRLHSIKAVMAATLGNLFIPIACGGGGIPVIVKDGHLRGVAGVID
                     KDFSAAKMAEDINADELVILTTVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGS
                     MKPKIEAAIEFVEKTGNLAIITSLSNANKLADGVGTIVYN"
     CDS             8689..9225
                     /locus_tag="ctg60_12"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDIKMNI
                     PGPIKNNRYLTKMFMFGINKLENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFEDQTSLGRLFDADVLVKNKQAAISRRDLGRQPRKCFLCDRPSKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             9305..10507
                     /locus_tag="ctg60_13"
                     /transl_table=11
                     /translation="MNKFIDVRIGISMKLKKNKNNLKQITALIQYAFLKNNDLTKDENF
                     MSRYDHSTGYGYFDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASCPEYRGQGHISQL
                     MKEILHDLHRQDIPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIV
                     RGKWDNLAVQNGVIQLYERQLHTNDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERP
                     MSYLIYRIRDNTFLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPE
                     QNELQVDLRPYMMSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRK
                     VAVERKEDALVDFSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDY
                     F"
     CDS             10523..10684
                     /locus_tag="ctg60_14"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             10686..11291
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_15"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-13,
                     bitscore: 41.5, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHDGAFA
                     KLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDMTCFI
                     VAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASGSGYFILNENTARLINTADL
                     QPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             11347..11457
                     /locus_tag="ctg60_16"
                     /transl_table=11
                     /translation="MKADSYILHSGDDFYAKKNFVTFNINGTCFRINWFG"
     CDS             11423..11929
                     /locus_tag="ctg60_17"
                     /transl_table=11
                     /translation="MVLVLGLTGLASQVETVDASTYGNGVQVTIPKKMQGTWYSYDRNA
                     HNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWMSGKTTKMKNDT
                     FYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKLAKKMKDYKFKK
                     VNYTL"
     CDS             11995..12687
                     /locus_tag="ctg60_18"
                     /transl_table=11
                     /translation="VTKLILGGEVMKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTS
                     QENEPGTLFMQTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVE
                     LFSEFIFTKAEKLAVTGSNDYVIYLTEIGVSLGKGDEFAHAVMKEMKTAVEEEKDILAM
                     IAGTVADQPNEWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKLQPDVIVD
                     QGAIFYQP"
     CDS             complement(12786..12914)
                     /locus_tag="ctg60_19"
                     /transl_table=11
                     /translation="MKGMRTLIKLLLIGGSFLTLGLMAISSVLINKPAVAKVKHRH"
     CDS             13258..14295
                     /locus_tag="ctg60_20"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKKPA
                     SKSKRVRTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYDNRNNYE
                     FDEASGLRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLID
                     VLRKM"
     CDS             14547..14738
                     /locus_tag="ctg60_21"
                     /transl_table=11
                     /translation="MNDFTKDFAQALFNPDKINDLLRKELQQAVNNLLEAELTAFLGYD
                     HYARNGWHTGNYTNGAAFP"
ORIGIN
        1 ctccctggtg gtctcgccct tggaggaagt gttgataatt agtcttacca tgatatccga
       61 ctgctgcttg gagtcaggca gcgtgtgctg atgaaattga ccgttgcgat cccgaggcac
      121 ttgcacttca attgggccaa attgcgtatc aactttgcgg aaataagcac catttctaga
      181 gttgccagta ttccagccat ttctggcata gggatcatag cccagaaatg cagtcaattc
      241 agcttctaac aagttattaa cagcctgttg tagctctttg cgcaataaat catttatttt
      301 gtctggattg aatagagctt gagcaaaatc tttggtaaaa tcattcatga aggagttctt
      361 ctttctgtat gttttttttt gttcaaacca atcatacgag aaaggaactc ctttttctaa
      421 tgtttaaaga aataaattta aggaatcatt catccttaca caaactattt tacagtctcg
      481 cggttcttta tgcggttcaa ggacaatttg taattcattt ttataatgac caaaattatc
      541 attgccaata ataacgtcac cgcgttgaaa ttctacttcg ttatcatgga taggattagg
      601 aatatcttta taggtaactc gctgcatagt tgagcgaata accgccttag ttaggtcacc
      661 tcggcggaag tgttgtggct tttcaactat tgttttttca atttcgttaa tgtcagatac
      721 ataatttacg tgtaatttta actgatagcg atttaattca aagagtgctt taagttccgc
      781 ttcactagca taggcgttgc caataattac atcatcaatc atatttgaag caaataaatg
      841 cattgcttgt acttcgattg gtaaatcgcg gtcttcttct aaagtaggga ggccatcttc
      901 aacattccaa ggaccaactt tgccaacttg actagagaca aaagcagcag agtgaatgcc
      961 aaaattttta aaacgtgtac tacaatctaa gaagaaatca taaggtagag ccgtgccgcg
     1021 ctgtggataa aaattatggc agccatagat gaaaggttgg ctggcttgat aagataaaat
     1081 attgttgagg tagtcagcat tattactcat gttaagttca ataattaggc cataaggatt
     1141 gtatgaaagc atggcctctg ttgcaccgtc aaaagcttca tcaagccgaa taccagctgc
     1201 accgatatct gcaaaaaatt tcagatctga ataatcaatt tctaatttct taaagagctg
     1261 aggtgataca tcaagaaaag tttggtagcc taatttattg ccgtagtcaa taatcttctt
     1321 atatttagct ggagtttctt cagggctacc ttgtacctca agcatactca taaaaatacg
     1381 agtaaagccg tatttatgac ctagttctaa gtatttcgta ttatcttcaa agttggtatg
     1441 atctggataa atggacagac caagtgatct cattgtcata aaagtacctc tttcttatta
     1501 atatgtctat accaattaga tcaagcttag cattataggt ctagtccaaa gcaagaaaag
     1561 cagtgaaata atacgctcaa aatatagtat gctgatagca attcgtctcg ttactttttc
     1621 agtaaaccag gtgttatatt aggtgtacag agtatgttta aaaagaggga aaatcaagat
     1681 ggaaaattgt gatcaagagt ctgagcgacg acaagtggat gcacttgggt taaatctttt
     1741 tttgagtaga atatatggcc ttggcggttt ttatttcagc taccagtgct tatctaacaa
     1801 tgacggtttt tgctagatca tttgctagct ttattgcggc tcatcaatgg gaagtgtggc
     1861 ttttaatttt actgccaatt gtttatggcg ttacttttgc ttttcttacc gaggcttata
     1921 gcggacacaa tgttgcttcg gctactgttt ttgtcattat ggcaattatc ggaactgtaa
     1981 ctaaaaaaga cctgagtcga attggttctt atgcttccgc tgctttaatc ggcttaattg
     2041 tagcaatggt aattaatttg tttttacata atcctataat tgattatatt ttttcaacta
     2101 ttgcggtcat tatttttact atattgacgg cataggatgc tcagcgcatg aagaatattt
     2161 atttacgcta tggtgatgat atttcaacta atggactagc agtgctgggt gcactgcagt
     2221 tatatcttga ctttgttaac ttgtttttac aatttctaga tatttttagc gcaagtgaaa
     2281 gtaattaaaa tttgacttta tgttaattca aatgaaataa gcacaatcta atatataagc
     2341 gtatgctacg aagatatagt tattattagg aaggttttta atgaaaaaat gcaaaaattt
     2401 gttgatggca attgttgcat tattaacgtt agttggggaa attagtgtta tacctgcgaa
     2461 tctacagaat acatcttatc gtaaaaaaga aggcgtaagc aacatgacag gactaaaatt
     2521 gttggtaata agcgatcaaa aatatttcat gtaatgcgtg gacataatta ccgaatgaat
     2581 cgcgaaaatg caattttctt taagagcaaa gcagcggctc gtgcggcggg atatcgtgag
     2641 tcaaaaaggt aaacgaaaag cacttccaag aatgtaattt cttagaagcg cttttttaat
     2701 gcaaaattga attaataatc tatctgtttt tcatcacagg ttggtaaatt aagtcgatta
     2761 ttatggcagc aataatcgct acaattacgg tgattgctag attttgaata gaaatttgga
     2821 ccattgccca accacaaaga gctaagataa aggtcaatag aacatctgca atttgaacac
     2881 taccaaccaa cttggatggg taatcttgcc aaaagtactt acgagttcta gtaatcaaaa
     2941 caatcaacat tgcgctaaga actaggtata cgtaaaccat agtagaaaca gcaccgtgac
     3001 tccaaccgtg tgtgtttaag aaccaaacaa acccaatacc gattaaagtc caaccagcag
     3061 ctagtgaaaa ggcgatctta gcaagcttag ccatattcca gttttctggc ttataagtaa
     3121 tgtgagtccg gtcggtccca atcatcatcg taaccatatt gttcataatg gtatagataa
     3181 ccattgcatt caaggccatt gggatgtagt caaagaaaag atagccaaaa gttaacagca
     3241 tcgttaattc agcagttcta gcaagcttgg ttagtgacca agtagtcatt ctttggtata
     3301 cgcgatgtcc agcgtctaaa attttaacaa ttgagcctag accatcgtct agtaatacca
     3361 ttttacccga acgcttagct acgtcagcag catttgaaac cgcgattcct acttcagctt
     3421 gttttaatgc aggtgcgtcg ttaactccgt caccagtcat ccctacgata tagccttttt
     3481 cttggaaaag ctttaccatc ttgagtttat cttctggtaa aacatcagca ataccggcca
     3541 aatcattaat atcagtattt tcattgaaat cgtgaatcga aattacttca ccagttaaat
     3601 caacttgttc tgccactgca gcagcggtct tttgattgtc accagttaac ataattgggc
     3661 gaacgccacg tttcttgagt tcagccaaag ctgctttaga gtctgttcta actttatctt
     3721 gtaagatgaa gacaccagct aacttatcgt caatcaagac tgccactgag cgtcctgcct
     3781 tgaaattaat tccagaaatt tcttcatcgg catgtttatc gatcaaggat aattgcttaa
     3841 atgaaccaag ctttacatta tgtccagcaa catcagccat agaataacca gtgtcagaag
     3901 taaatggagt aaagttttca gcattcatga ctggaatgtt attttctact aagtattcat
     3961 cgattgctgt atcgataata ccagcattac gtttatcagt tgcggctcca gctaaagcaa
     4021 gcacgtcttt atcaggcaag tcacttagat cagtccaagc ggctacggca gttttgtttt
     4081 ccgtaattgt tccagtctta tcaagtaaaa gcaagttcaa gttagctgcg tcctgaattc
     4141 cagttaggtc agaagtcagg actccttctt tacttaagcg ggttgcttca aatgagttgg
     4201 ataaagcaaa agttgatggc attgctacag gaattgaagc aataaacatc attgccagga
     4261 atggcaacat attaataaag gtattgaaat taccgccttt gaagaaggag gcgataataa
     4321 taactaaggt taaaacacca tctagtaagc aaaggtagta gataatctta gtcaaaagtt
     4381 gttgtaagtg accaggagca gcggaattgt tgatcaaatt aatcgtctta ccgcttctag
     4441 aatctttacc tgtagcagta acaacagcta ggccatcacc ttcaacaact gtagtaccgg
     4501 caaaggcggt gtcatcaatt gctttcttaa ctggtttaga ttcacctgta attgagcttt
     4561 catcacaagc taagttaccg tcaacaattt taacatctgc tgcgagtacg tccccgcgtt
     4621 taagtgagat taaatcgcct ttaactagtt gtttagaatc aagtttgatc cacttgccat
     4681 cgcgttcaac tgatacagta ggagtcaact tgtgtgaaat attatttaaa actcgtcttg
     4741 attgcttttt cttagatgca ccgttaaatg cagcaaataa aagcatcaac aacacgaata
     4801 atgattggac ccatttgccc aagatacatt ctagaattaa agcagcttct agaatccaag
     4861 cggataggtt ccataactta gacaagaatt ctttaaagaa attatattca ggctctggta
     4921 cttcatttaa gccatcttct tttaagcgct tgtctgcttc ggcttgagtt aagccgtgaa
     4981 atttatcaga cattattttc cctccaaatc taccttaata aggtagcaca gatattgcta
     5041 tgaataaaat actaaaatac aatataagat attaaatatt ttaatatcac tatcaattga
     5101 aataaaaaaa ggataaataa tatgaatcta aaacagttac gttattttct agttgtagca
     5161 gaagaaaagc agattacagc agctgctaag cgcttgtata ttgcacagcc accattaagc
     5221 tatcaattaa aacaattaga gaaagagttg ggcgcgcaat tatttaaaag aacggcacat
     5281 ggtattgagc taactgatgt gggacaaatt tttcaaagct atgccaatga aattatttct
     5341 ctagctcaaa atgctgaaaa ccaagtacat aagactattt ccggtgaatt gggaacgatt
     5401 gcaattggaa tggcatcttc ctcaacgggc ttgataccaa tgaattcttt taatgaatta
     5461 cgaaaatatt atccggaaat ttcttttgat atttatgaag ataatactta tggcatcctg
     5521 gataaattag aaaaaaagac aatcgatcta ggcattgtac gaacgcctta caaccagaca
     5581 ggtttaaata ctaagacttt aacaactgaa aaaatgatgg ctattagtgt agacccagat
     5641 tttcagcaaa aaaaagaatt acgcattaaa gatctagcag atcagccgtt gattatttat
     5701 cgccgctttg aggatatttt taatcaaact tttgcacatc atgggcttaa gccattttat
     5761 gcggttaagt gtgatgattc acggacagca attacttggg ctaagagaaa aatgggagta
     5821 gcgctagtac cagaatcaat tgcgacaact tatgcccaag aaaatatgat cgcaattaaa
     5881 catgctaatt ggataacaca tttgcagctg gtttggcgta aagatcatca agttacacct
     5941 ttaatgaaaa aaatcattga tgcaatatga taatactgta acttttgcct aattgatcca
     6001 taatcaatgt aaacggatac aataattaat agaaggcggt tgaatgtcga gtccgattca
     6061 tgtttattca gaaattggta agttaaaaac ggtgatgtta catcgaccgg gaaaagaact
     6121 agaaaatcta gccccagata ttttgcatcg aatgttaatt gacgatattc cttatctgaa
     6181 gattgcccaa gaagaacatg atgcttttgc gcatgtattg aggcagcagg ggatcaaagt
     6241 attatatctt gaggatttat tagcagaatc tttaacagat gagaaagttc gtcgggcatt
     6301 cttagatcag ttactggatg aatcaagtat taaaaaacag gatcctttgc atcaattatt
     6361 gctgaactat ctccaagaat tgccaactaa ggaaatggta aaaacggtga ttgctggaat
     6421 tagaaaaagt gcgattcata attctacccc atctttagca gatttggctg aggacccaga
     6481 ttaccctttt tatcttgatc caatgccaaa tgtatatttt actcgagatc aacaggctgc
     6541 aattggttca gggatgacca ttaaccggat gactttcaga gctagacgac gtgaatcatt
     6601 atttatggaa acaattttga aaaatcatcc tgatttcaag aacgcaacta ttccagtttg
     6661 gcgtgaccgt tatcatcatg gtcgccttga gggcggggat gaactagttc taaataacca
     6721 tgtgttagct gtaggtattt cacaacgcac ttctgcaact gcaattactg acttagctca
     6781 taatttattt gatcattcaa gttatgatac gattttagcg attaagattc cgcacaatca
     6841 tgctatgatg caccttgata cagtttttac aatgattaat tataatcaat ttacggttca
     6901 tccctttatt ttagataaag ccggcaaaat tgatatttat gttctacagc ccgatgatca
     6961 caacggtgta aaaatcacag aaaagaatga tttggtgcag gttttgaaag aaaacttgca
     7021 tttaagcgaa ttggatttaa ttccaactgg cggtggtgat ccaattgccg caccacgtga
     7081 gcaatggaat gacggctcaa ataccttggc aattgcacca ggtgaaatcg ttacttatga
     7141 tcgtaattat gtatccaatg atttgttaag aaaacatggc atcatcgttc atgagattcg
     7201 gtctagtgaa ctctcacgtg gtcgtggcgg tcctagatgt atgtcgtgtc cgttgattcg
     7261 tgaagattta taagaggcaa aaaatgaaat atttacaaaa tgtttttcaa ggtagaagtt
     7321 ttctcgattg taaagactat actccagctg aaatttcata tttaattgat tttgcattac
     7381 atttaaaaga acttaaaaaa gagcatatcc cacatgaata tctgaaaggt aaaaatattg
     7441 cactactttt tgaaaaagcc tcaactagga cgcgatctgc ttttgtagta gcttgtaatg
     7501 atttaggtgc tcatccagaa tatctaggcg caagcgagat ccacttaggt aaaaaagaaa
     7561 gcgtcaagga tacggctaaa gtcctaggct caatgtatga tggaattgaa tatcgcggtt
     7621 ttgctcaaga agatgtagaa gagctggcta aatattctgg cgttcctgtt tggaaatggg
     7681 ttaactgata aatggcatcc tactcagatg ttggcagatt ttatgaccat gaaagaaaag
     7741 tttggtcatt tgaagggctt aactttagct tatgtgggtg atggccgcga taatgttgcc
     7801 gacagtcttt tagtttgtgg ctcaatgtta ggtgttaatg tacatattgt tacacccaag
     7861 cctttgttta cacatcctga tgtacaaaaa attgctcaaa attttgccca agattcaggt
     7921 tcaaaaaatt tgatcacaga tgatattgct cagggcgtta aaggagccaa tgttgtttat
     7981 accgatgttt gggtttcgat gggtgaaatg attggtctga acgaattaaa ttattaaagc
     8041 catatacggt cacaatgaaa atgatgcaaa tgactggtac accagatgac caattgatct
     8101 ttatgcattg tttgccagct tttcatgatc gaacaactca ggtgggagaa gaaatctatg
     8161 aaaaatatgg cttaaatgag atggaagtaa cttatgaggt ctttaattca aagtatgctt
     8221 ggcaatttac agaagctgaa aatcgattgc attcaattaa agcagtgatg gcggctactt
     8281 taggaaattt atttattccg attgcctgtg gcggtggtgg catccctgtt attgtgaaag
     8341 atgggcatct cagaggtgtt gccggcgtaa ttgataaaga tttttccgct gctaaaatgg
     8401 cagaagatat caacgctgat gaattagtaa ttctaacaac ggtggatcat gcatttttga
     8461 attatggcaa agaaaatcaa caagcaattg gtaaaataaa agttgaacag ctcaaacaat
     8521 atctagcagc aggttatttc gcagctggga gtatgaagcc taagatagaa gctgcaattg
     8581 aatttgtaga aaaaacaggt aatttagcaa ttatcacctc tttgagcaat gccaataaac
     8641 tagcagacgg agtcggcaca atcgtttata attaacaggg tgataaaaat gaatattttt
     8701 aatgaaggaa aaaagcagga tattgcccaa gttttagcag ctaaagatag gcgagtagct
     8761 gtacaacata agatttttaa taagtatcct aatcaaactc tagtcgacat taagatgaat
     8821 atcccaggac caatcaagaa taatcgctat ttaactaaaa tgtttatgtt tggtatcaat
     8881 aagctggaaa atgcttggac taacctaggt tatcatttta aattggtgac acagcttaat
     8941 gatgatagtg gctgtgaaaa cttctatgta ttatctttgt caattgaaaa agtaaagcgc
     9001 tcaacaattg attttgaaga tcagacatca ttgggacgtc tctttgatgc agacgtgttg
     9061 gtaaaaaata aacaagctgc aatttcacgc agagatttgg gcaggcagcc acgtaagtgc
     9121 tttttatgtg atcgcccttc taaagaatgt gctcgcagcc ggagacattc agtggaacag
     9181 atgcaggcat ttatctctca gctttatcaa gaatacgttg cgtaaaataa accgggattt
     9241 tatgattccg gtttattttt atgaaaaatc tagttaaaaa ttaaaaaaat gaactaaaat
     9301 agtaatgaat aaatttatag atgtacgtat aggaataagc atgaaattaa agaaaaataa
     9361 gaataattta aagcaaatta cggcattaat tcaatatgca tttttgaaaa ataatgattt
     9421 gactaaagat gaaaatttta tgagtcgtta tgatcatagt acaggttatg gctattttga
     9481 taaggaaaaa ttagctagct atattatggt taatcgattt aaaagtgatg tttttgggca
     9541 tcatttaccg atggctggaa taggttatgt agcttcatgt cctgagtatc gtggccaagg
     9601 tcatatttcc caattaatga aagaaatttt gcatgactta cataggcaag atattccgtt
     9661 tgctaacctg gcaccatttt cggagagctt ttatcgccag tacgggttta gcaatagtat
     9721 ttatcaaaaa gaatatcgct ttgatggaag cgcattgcgt agttttaaat taccacgttc
     9781 tggtcatata gtgcgtggca agtgggacaa tttagctgtt caaaatggtg tgattcaact
     9841 ttatgaacgt caactgcata ctaatgatga acgtaacacg gttgtacgtg aggcatggtg
     9901 gtggaataga cttgattctt attatcatca ccgcaatgta gccgtttatt ttgacgcgga
     9961 tgagcggcca atgagttact tgatttatcg cattagagac aatacttttt tagctgatga
    10021 aatgtacgca attacgccgc agggattact gagtatgttt ggttttatgg gttcgcacgc
    10081 gggcagtgtt aagcaattta aaatgagtgt accagagaaa tcgttacgag ctgaactttt
    10141 tcctgaacaa aacgaactcc aagttgattt gcgtccttat atgatgagtc gaattattga
    10201 ttttgaaaaa gttttggctt gtatgcggcc aatgcaagaa ggtgatttta atctggaagt
    10261 caatagcgat gaacagtgtc cttggaatat tggagtttgg caattaagta atcatggacg
    10321 taaggtagcg gtagaacgta aggaagatgc attggttgat ttttcgggat caattaccgc
    10381 gtggacccag gtgctattag gtagactaac catgaatgct gctgttaaac taggattaat
    10441 tacagattac cgcatcaaaa aattagattt cgttaaaggc gatgtatcat tttatgatta
    10501 tttttagttg tgaggttaaa aaatgagtaa agaaaagaaa ctcaatttaa taaaattatt
    10561 tggcattgta gttagtggtt tgaatttgat cttttttgcc ttgatggcac ttaataagca
    10621 tgaagatact aaggataaaa gaagagtagc agaagaagga cacgcaccgc tggatgaaaa
    10681 ataaaatgac ggaattaaag attgcatatt ttgaccaatt aggtcgtaag gaattagatc
    10741 aggcagtgca gcattttgtg ttaaaacatc ctaatgtaga tgtaaaacta cttgcgacta
    10801 gtcatgatgg tgcttttgca aaactgaatg aagatgaagc agacatagca atcaatgatt
    10861 tgcgtgacga gaatcttaac tttgatgaaa cagaattgac tcaagctggt gtaatggcaa
    10921 ttttgcccaa gggaatgtat cctaatggca ttcaaatgat tgaaaaagac gagctcaatg
    10981 atatgacttg ttttattgtg gctaaacctg aagaagaggt tagtgagcta catttattta
    11041 aagatttgta tcaaattggc agtcaattca tcgcttctaa ctcggttgaa gaagcagcac
    11101 tgttggtcgc ctctgggtct ggctatttta ttttaaatga gaatacggct aggttaatta
    11161 atactgcaga tttgcagcca cttttcttgc ttgatcatgg tcagttaata aagcaaaaga
    11221 taatggcttt ttataagtca aattcagcgt taagtagtga gtttataaaa ctattgcagc
    11281 aagaatatta atctgtaaag ttaaaaatat cttgtctaag tactataaga tactgtaaaa
    11341 tatattatga aagcggattc atatatttta cattctggag atgattttta tgctaaaaag
    11401 aactttgtta cctttaacat caatggtact tgttttagga ttaactggtt tggctagtca
    11461 agttgagact gttgatgctt caacttatgg taatggtgta caggttacta ttccaaaaaa
    11521 gatgcagggt acttggtact cttatgatcg taatgcacat aatggcacaa agatcacctt
    11581 tactgaacat actgttaatg gcaaaccaat atttacccag gaggcttcga caattagtga
    11641 ttacttcaat ggtagaattg ctaaccagaa gaactttgat aaggtaacgc aaaactggat
    11701 gtctggtaaa actaccaaaa tgaagaatga tacattctat gagattgatc cgtggattac
    11761 ttttgaaaat tggagtcttt atcgagtggt accacaaacc attaatggta aaaagcataa
    11821 cgtgctggtt tattctagta gatatgatgg tggtaactac ttcagaagca agaaattagc
    11881 taaaaaaatg aaggactaca agtttaagaa agttaattac acgttatagt tttgtgacat
    11941 cccttaacta agggatgttt tttactaata gacgcggtaa aatttagtat aatagtgaca
    12001 aaattaattc ttggaggaga agttatgaaa ttaaaacaaa caccaatttt gcgtttatat
    12061 aaactagaaa ctaataaaga ggatcatgca aagttcgtta aggcagggca acataatatg
    12121 cttacttctc aagaaaacga accaggcaca ttgtttatgc agacaagtca tgacgaagaa
    12181 actactaatt ttgtagtaga atgctatcaa gacgaagcaa gttatgatac tcatgctaat
    12241 tcaaagcaat ttaaggattt tactgacgtt gctaaagata ttttaactag tcgagtaaag
    12301 gtagaattgt tttcggaatt tatttttaca aaggcagaaa aactagcagt taccggatca
    12361 aatgattatg ttatttatct aactgaaatt ggtgtttctt taggtaaggg cgatgagttt
    12421 gctcatgctg taatgaaaga aatgaaaacg gcagtcgaag aagaaaaaga tattttggca
    12481 atgattgcag gaactgttgc cgatcaacca aatgaatggt tagctattga agtttatcgt
    12541 aataatgaag cttacaagca gcacttggaa actaagaact tcaaagagta tttgaataat
    12601 acaaaatatt gtgttgaaag taagagttta cgtaagttgc aaccagatgt aattgttgac
    12661 caaggtgcaa ttttctacca accataaaga ataagacgaa aagaagacca ggctatgtgg
    12721 agtacataac ctggtctttc tagttagagg ggaaaaagat ttattaacat atattattct
    12781 ggtttttagt ggcgatgttt tacctttgct actgctggtt tattaattaa tactgagctg
    12841 atggccatta aaccaagcgt taaaaatgat ccaccaatta agagtagttt aatcaaggtt
    12901 ctcattcctt tcatcttaat tgatcttata atagcgaaat aatattaaga atttatatgt
    12961 aaaacctaat ggattagtta agaaaataaa actagaaaaa aggctggtta gcacgtaaaa
    13021 tagaaataga gtcaaagtct agtgcaactg cgcataaaat aaagcagtat cgatgggatg
    13081 ctgcttgttt tggttaaaaa atagagaata tgcttgtagc ccttttcgta aatagcgtta
    13141 atgttgtaaa atggaaagtg cattaagttt attaatgaga aaattgatgt attattgcaa
    13201 aaaaggccgt aatggccctt tttgttgtga aaaaactaaa agaatatagg attggaaatg
    13261 ccaggaatag tagagcaaac attattagaa caacaaaata ttgatttaaa tgaaatggta
    13321 acaatgaatc aaatgattga tcaattgttg cctaatgcaa gtaaagaatt acaacaaaaa
    13381 ctaaagatta aaatttataa ctttgtgcgt acacgtaaac aaccaagtat tactgtgcga
    13441 agaagaaaat attttaagcc ggctgttgct aaattaatta ttggtaatgt acaagattac
    13501 gcagatgcaa ttgaacgtcg tgctaaggaa gccccagcta aagaggatgc tactgataag
    13561 aagccagctt ctaaatctaa gcgggttagg acaattacta agcgtaagat tttagctaaa
    13621 gttataaaga atgataagat tgataaatct attcaaaaga aattagaaga taagattgct
    13681 tcaattgtga agaccaactt tattaagcca gttaacaagc ggggaagttt ttcggttgaa
    13741 gatggtgaaa aagttatagc tgaacttagt cctttttatc aaaatatcaa gattgatcaa
    13801 aagtatcgca agaatgctga aaaagcggct gaaaataagg aaacagaaac taaagaaaag
    13861 cctgagcaac attctaagga tcagaatgaa agtcgtgaag gtcaatctaa ggactttgag
    13921 cgtaagaata atcagaagaa tagcaataat cgaaataata atcaaacgca aaatcaacgt
    13981 aagcgacaaa ataagcatcc ttttgagatc agaagagaaa ataataaccg ctcacgtaat
    14041 aatcagtcta accgccgcta taataatcga aataattatg ataatcgaaa taattatgaa
    14101 tttgatgaag ctagcggttt gcgtgaacgc tacaatacag taatcagaaa ttacaatcaa
    14161 ctggagcaaa gatataatgc tttgcaagat aaatataatc aggctttaga tgataaagct
    14221 agattgatcg aagaaatggg caagaagaac gaagacttac gtcgtgtatt gatcgacgtt
    14281 ttgcgaaaaa tgtagttttt ggtaaagaaa gagactagta gtcaatttga attgattact
    14341 agtcttattt tatgtttatg aaatatgatt tagcttaaaa attaaaaaaa atatgtgtaa
    14401 aaaattattt ttgtgagact gtaaaatagt ttgtgtaagg atgaatgatt ccttaaattt
    14461 atttctttaa acattagaaa aaggagttcc tttctcgtat gattggtttg aacaaaaaaa
    14521 acacatacag aaagaagaac tccttcatga atgattttac caaagatttt gctcaagctc
    14581 tattcaatcc agacaaaata aatgatttat tgcgcaaaga gctacaacag gctgttaata
    14641 acttgttaga agctgaattg actgcctttc tgggctatga tcactatgcc agaaatggct
    14701 ggcatactgg aaactataca aatggtgctg ctttcccgaa
//
