LOCUS       c00013_gnlPro..        15711 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EGFNODHL_13.
ACCESSION   c00013_gnlPro..
VERSION     c00013_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 05:11:27
            Original ID  :: gnl|Prokka|EGFNODHL_13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15711
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15711
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2567:5711]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2568..5711
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15711
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15711
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             102..263
                     /locus_tag="ctg13_1"
                     /transl_table=11
                     /translation="MFCSRFKIKRPYTFDSSKLCSVFKDLIPCVNRLTQLNHHNILINI
                     LSTTFFKK"
     CDS             505..1020
                     /locus_tag="ctg13_2"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACARSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1188..2177)
                     /locus_tag="ctg13_3"
                     /transl_table=11
                     /translation="MRMLEKIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARFLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2568..4853
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_4"
                     /sec_met_domain="Gly_radical (E-value: 5.6e-40, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 9.4e-247, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDSNYGGEKMITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFT
                     QYNGDESFLAGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDL
                     EKIVGLQTDKPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVY
                     TPDMRKARHYKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDD
                     VIRLREEVQDQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAM
                     SVGRIDTTMDIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIW
                     ATLSMCGLGVDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSI
                     DSSTIQYENDDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRD
                     EIAGDQVGPAYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQ
                     LALKNTDLDRTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNN
                     DDRADDIAKWLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEP
                     FSPGANPAYGAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVN
                     MLDGYMKNDGMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVI
                     SRTFFESM"
     CDS             4890..5711
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_5"
                     /sec_met_domain="Radical_SAM (E-value: 8.8e-28, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             5799..5951
                     /locus_tag="ctg13_6"
                     /transl_table=11
                     /translation="MHVLLAGISTVARKKGAASKPATSFLNHALSNDRQPLDWLRTGRP
                     LTMNA"
     CDS             complement(5934..6263)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 66.9; E-value: 4.7e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg13_7"
                     /sec_met_domain="FeS_assembly_P (E-value: 1.7e-21,
                     bitscore: 66.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGRDTMTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAE
                     GTAEITMTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARME
                     LGIHS"
     CDS             7305..8225
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVILGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8395..8589
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLR"
     CDS             8599..8919
                     /locus_tag="ctg13_10"
                     /transl_table=11
                     /translation="MSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPRHNGDTPNPG
                     PVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEALTRPASHRID
                     SN"
     CDS             complement(9014..9259)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_11"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 4.8e-05, bitscore:
                     13.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSRPDK"
     CDS             complement(9708..9824)
                     /locus_tag="ctg13_12"
                     /transl_table=11
                     /translation="MLLLAQQVFEGFDFRSVLSHPFLVVRMGVGIADFKAGF"
     CDS             complement(9963..10604)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_13"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 5.8e-20, bitscore:
                     63.0, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLATVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAVRYQAIPEDADFIAVFGGVNDYGRDQPLGQYGDCDMTTFYGA
                     LMMLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIVRKLQSFLDSHF"
     CDS             10866..11153
                     /locus_tag="ctg13_14"
                     /transl_table=11
                     /translation="LLSGISPLSIGRNAFHSGQYSNGGRRYTQLLMNLSLFSINSNFIN
                     QLLGRKDIGIARYFGITIVIIEHLNKVVRVTLTSRLKFRYQNSQRPIVPS"
     CDS             complement(11442..11573)
                     /locus_tag="ctg13_15"
                     /transl_table=11
                     /translation="MDFHNTSLLRLAHLFEIMVERCLLGLVFCSSAGERPIPTSGAG"
     CDS             complement(11620..13146)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 400.2; E-value: 3.5e-122)"
                     /gene_kind="transport"
                     /locus_tag="ctg13_16"
                     /sec_met_domain="BCCT (E-value: 1.3e-122, bitscore: 400.2,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEF
                     STYHWGSMVYATGIDASILMLSMVDPLRYLQSPSFGVKPFSISAYNYAHMLGQFNWGPM
                     AWMMFAPATIAIAYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGV
                     GTSVGMEIPVISKVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHV
                     WLAIGFLIVVLIVGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWG
                     WWLSFMPVMGLFIARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNL
                     VHILNTQGQAAVIAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAA
                     GEQPSRFNRMSWVVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLT
                     TDPVKEAAKANAKAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
     CDS             complement(13638..13784)
                     /locus_tag="ctg13_17"
                     /transl_table=11
                     /translation="LYKPTCAVQVVTCYPVLSAFLVHQAINLTVVRWAYLVIQGGYLLA
                     RAV"
ORIGIN
        1 ttcgtcctga gccaggatca aactctcaaa ttaatgatga gttctaaaaa gctcatttaa
       61 tgttgtacta aaatttattt gctagcgaat tgacttcgca aatgttttgc tctcgattca
      121 aaatcaagag accctacaca tttgattcgt cgaaactttg ttcagttttc aaagatctaa
      181 ttccgtgtgt taatcgctta acacaactta atcatcataa catcttaatc aatatcttgt
      241 caacaacttt ttttaagaag taacttgatt aatttgtcat agttgccgtt gcgacaacag
      301 aagctatctt accaattact gaagaaattg tcaacaacta atttcaataa ttatttggtg
      361 gtgagatgca tctgccgtag cagcaacgtt tactaatata ccaattgaag taaaaagtgt
      421 caacactttt tctgaatttc tttttattaa tagtcaaacc agctttcttt ctctatacta
      481 tttaattaaa ggagcgacta aattatgcta gcttggctac cattcttttt gatttcatta
      541 atgtttattg ttctactata cgcttgtgcg cgatcagcgc gcacaaatat ccagcgtttt
      601 aagcaactca gtttaattgc ctttctctgg gtcttaactg ctttttgcta tacacctacc
      661 agttacaatt ttggtaccca actcgttatt caatatattc aatggggacc cgttaagctg
      721 aacgtgattc ctttccaaca acttgacatt gaattttggc tcaacgttct cctcactgtt
      781 ccattgggcg gtttactggc atggaatttt cccgacttgc cttggcgtcg ttttatttgg
      841 ttgggatttc ttacggggct aacactcgag ctgggacaat tcatccttga ctggttggtt
      901 aacctcaaac gttgggttga tatcgatgat gtcatcacaa attgggctgg tgtcattatc
      961 ggtgccgctg gttataaaat tgcacgtcat gttcccggac ttcgctggtt gcaaaaataa
     1021 cgtatatata gaagcaaaaa gcaaaacaac gtttgtttag cacccacaag tgccaaacac
     1081 ttcagcgctc tagctgttat gaaatcgtaa ttaaataagc gtcgcagcca cttaaggttg
     1141 cgacgcttat ttaatttaac tactaactat taatgaagct gccatcatca ggattcaaaa
     1201 aacagatcga atactcgctt acgatcttgg ttccagactt gattgtcact agttggataa
     1261 actcgatttg ttaacacaac cagcccaatt tgacgatcca aatcaaaagc aactgccggg
     1321 ccagtaaaac cagtatggaa atattgatgt cgtcccgcac gtcgttccca acctaacgtc
     1381 cggccatttt cgtcatactc gcctaaccag tcaaagacat tttcatccag cacccgtttg
     1441 ccttgatatt caccaaagtt taacatcatt tcaataaata cggataaatc cgtcagcgtt
     1501 gagaacaagc ctgcgtgacc actctcacca ttcaacaaaa aggctttata atcatgcacc
     1561 tgtccttgaa tctgaccccg ccgcggatca aactccgtcg gcacaaaccg aatcttcgga
     1621 cgatttaagt tataacccgt attggtcatc gctagtggat agcaaacgtg gtcttgaata
     1681 ctccgagcca atgagccgtc aaccgcacga ataatccatc ccaataaaat aaatcccagg
     1741 tctgaataga catacgttgt ccctggcgcc gtgacgagtg gcgcatcata aaccgctttg
     1801 atcagatctt cacgttgcat cttatccagg ttatcaatat ctgccggtaa cccactatta
     1861 tgaagtaaca agtttttaat cgttatttca ggatgagtga acccaggtaa aaaccgggca
     1921 accgagtccg ttaaatgaat cgtgtggtcc gataacaact gaaaaatcct cgtcgtggtc
     1981 cctacaacct tagttaccga tgctaggtca taaatcatcg caggatctaa gcccacggca
     2041 aactcatcgc ggccctgctt accatgatag tattgattga tacctttagg ggtgatcaag
     2101 ctaaacgacg ccccataaat gtcgccagct tcaatacaac tgtcaatata ttgttcaatt
     2161 ttttcgagca tccgcattac gcccaccttt cactacattc actagtttct gcttatcttc
     2221 tttatgataa cgaacttcct cataaaatca acggcaaacg cttttaacac cctccacacc
     2281 tcgttgcact ttttattaat taactagtta aacacttgtt acattatgga caatattcca
     2341 cttatatatc aaaacaagtc ttgtttttag ccgttttcta aatataatta agtgaattac
     2401 caatgcctat ctagctatgt aagtactgtt atatcaacgt taatagtcaa cttttcaata
     2461 atagattgca aaaaaataac ccaaacgtga aataaatcac ctgaaagcgg ttacaaatcc
     2521 agcaaaaaat gttatgattc aaatatagaa ttttatcaat catttgattg gattcaaatt
     2581 atggaggcga gaaaatgatt acatcagaaa agacaacaaa accagcagct tggaaaggtt
     2641 tcaaaggcgg gcactggcag gaagaaatca acattcgtga ttttattcaa aataacttca
     2701 cacagtacaa tggcgacgaa agcttcctgg ccggaccaac agccgctact aagaccttga
     2761 atgacaaagt cttagaatta aagaaacaag aacgtgccgc tggtggtgtg ttggatgctg
     2821 atactaaagt cgttgcaacg attacttcac acggccctgg ttatattcaa aaagatctcg
     2881 aaaagattgt tggtctccag actgacaagc ctttgaagcg ggccttcatg ccatttggtg
     2941 gtattcgaat ggctgatgac gctttgaaat catacggtta tacccctgat gaagaaaacg
     3001 acaagatttt cactgaatat cgcaagactc ataaccaagg cgtcttcgat gtttatactc
     3061 ctgacatgcg gaaagcacgt cactacaaga tcatcaccgg actaccagat gcatacgcac
     3121 gtggccgtct cattcctgat cttccacggg tcgctgttta tgggatcgat cgtttaatgg
     3181 aagacaaagc taatgacttt gcccacattg gtgatggtga attgactgat gatgttattc
     3241 gcctccgtga agaagttcaa gatcaatacc gtgctttagc agatatgaag aagatggctg
     3301 ccagttatgg ctacgatatt agcaagcctg caactaatgc tcaagaagct attcaatgga
     3361 tgtacttcgc ttacttagct gctatcaaga cccaaaacgg cgctgcaatg tccgttggcc
     3421 ggattgatac aacgatggac atcttcatcc aacgtgactt ggacaatggt gttctggacg
     3481 aaagccaagc tcaagaatta attgatcaat tcgtcatgaa actacggatg gttcggttca
     3541 tccgtactga agaatacaat tctctcttct ctggtgaccc aatctgggca accttatcaa
     3601 tgtgtggttt aggcgtcgac ggtcaacacc atgtgactaa gaccgctttc cggattttaa
     3661 agactttgga caacatgggc gccgcaccag aaccaaacat cacgatttta tggtcagacc
     3721 gcttaccaga agacttcaaa cgttacgcaa ctgaagtttc aatcgacagt tcaaccattc
     3781 agtatgaaaa tgatgacttg atgcgggtac aatggggtac cgattattat ggcattgctt
     3841 gctgtgtttc cgcacaacca attgctgatg gaatccagta cttcggtgcc cgggcaaact
     3901 tagccaaagc gattctttat gccatcaatg gtggccgcga cgaaattgct ggagatcaag
     3961 ttggccctgc ttacgaacca attacttcag aatacatcga ttacgacgaa ttcatgaaga
     4021 aattagacaa gcaaatggat tggttagctg acacttacgt gaactcactg aatgcaattc
     4081 attatatgca tgataagtac tactatgaag ctgcccaatt agctttgaag aatactgatc
     4141 ttgatcggac ctttgcaact gggatttctg gcttatcaca tgccgcggat tcaatctcag
     4201 ctatcaagta tggtcacgtt aaagtaattc gtgacgaacg tggtatcgcc gttgacttca
     4261 aagccgacaa tgactaccca cgttatggga acaatgacga tcgcgctgat gacattgcta
     4321 aatggttagt caaagaatta tacagcaaga tgaacacgca tcacctctat cggaatgcca
     4381 aactttcaac ttctgttttg acgattacct ccaacgttgt ttatggtaag aacactggta
     4441 ccacaccaaa tggccgtcaa aaaggcgaac cattctcacc aggtgctaac cctgcatacg
     4501 gtgctgaaaa gagtggtgca ttagcttcac ttctttcaac tgccaaatta ccataccgtt
     4561 acgcaactga cgggatttcc aacacgttcg gcgttacccc taacacgtta ggccatgacc
     4621 tcgaatcacg gaaagacacg ttagtaaaca tgttagacgg ttacatgaag aacgatggga
     4681 tgcacttgaa catcaacgtc ttcaataaag acactttgat tgatgctcag aaacaccctg
     4741 aagaataccc aacattaacg gttcgggttt ctggctactg tgtctacttc gcagatttaa
     4801 ccaaggaaca acaagatgac gttatttcac ggacattctt cgaatcaatg taacatttaa
     4861 tctttaatag ttaagaaggc gaaaggctca tggaaaacaa acaagtttca acaacgcaag
     4921 cggcggcaaa agagcctttg ataggctacg ttcactccat cgaaacgttt ggctccgttg
     4981 acggaccagg tatccgttac gtggcattcc ttcaaggatg ccacatgcgt tgccaatact
     5041 gtcacaaccc tgatacttgg aaactcaacg ttggcgatca aatgacggcc gacgagattc
     5101 tcgaagacgc ggctaaatac cgggctttct ggggcaagac gggtggcatc acagtcagtg
     5161 gtggtgaatc actggtacaa atcgacttca tcttagactt attcgaaaaa gccaaggcga
     5221 tgaatatcag tacttgtctg gatacctctg gacagccttt tacccgagaa caacctttct
     5281 ttgacaagtt cgaacgtcta atgaaggtca cggacatttc gttggtcgac attaagcaca
     5341 tcgattctgc caaacacaag cagttgaccc agtatgggaa cgaaaatatc ttggatatga
     5401 ttcagtacat ggcccaacac cacgatgata tgtggattcg tcacgtcctg gttccccaac
     5461 ggactgatta cgatgaagac ttgaagaaac tcggcgatta cattgctaag attccaaacg
     5521 acgtcgttca aaaagtcgaa gtattgccgt accatacttt gggcgttaaa aaatatcatg
     5581 aaatgaagat caagtaccgg cttgaaggaa tcgagtctcc aacccaagat cgggtggcaa
     5641 atgccgaaaa gctactgcac actgctgatt acaacgggta caagacatgg atgccattgc
     5701 caaaacttta aatcggcatt tctagcatga ctaaaacacc agcgttacaa tcgtctacgg
     5761 atggttgtgt cactggtgtt tttttgctgg ctcgacgcat gcacgtattg ctggccggaa
     5821 ttagtacagt ggcacgcaaa aaaggcgccg cgagcaaacc agcaacgtct ttccttaatc
     5881 atgccctatc caatgaccgt cagcccttgg actggctgcg aacaggccgg ccactaacta
     5941 tgaatgccta gttccattcg agcttcgcgg gacatcatac tttcgttcca agcaggttcc
     6001 cacacaatct caatctcgat attgttaact tctggtaatt tgatcagttc atcgtgaatg
     6061 tccttagcca accattcggt caaaggacag cccgcaatgg tcaacgtcat ggtaatttca
     6121 gcggttcctt ccgccgtcaa ttgtgcatca tagatcaacc ctaagttaac tagatcaatt
     6181 cctaattcag ggtcaatgac atgtcctagc gcctcgaagg cccggtcttt aaacgttgtt
     6241 gtcatcgtat ctcgtccttc cataccagct tgaattcact gattaatcac gccaacgttt
     6301 cgcggtataa gtgccaccac acttgataca cgtcatcgtt atataaagcg ctttcttgtc
     6361 tacttctatt gtaccgtatg tcagcccata ttcaatcaat tattagcgct aattagccga
     6421 cttttcaaac gatcggtcaa tcagcaaatc atgcgactat ttctcgaaaa aatttactat
     6481 aatccccgat atagcagcgt tttgagtcac tattgatttt tattgcgaat tcgcggttgt
     6541 ttttgttgta agcgtttgcg gtttatgcta ttatactaag tgaggaaagg aattaatcct
     6601 cgattagcaa agcttctcaa aagagtttgg ctgtcgctgt aatgttagac agctagtatc
     6661 acagtttggg tcgttatcga aaccgtttta agcgccgtga agcgttatcg gtctagcgag
     6721 tgtcgtgaga tttacgttgg atgactgaac gttgaccctt agataaacga taaccgcaaa
     6781 gaattaattg gcattagaat gacgaacaga ttttaactaa gttttagttg gaaacaggtg
     6841 tctccgatga ccagttgtta gttccacatt accagttcca tttgtagact caggtattac
     6901 aaagtttaaa cggaggtgca tgtctgttac gaagacattc ccaagtttta aacgcgagtt
     6961 tgactttcgt taaaacccgt ctaacgagtc gcaatcaagt aacaacctta ctttagatcg
     7021 actatagcag atagttacaa taaatacggg ttagtccgtt agaagttgga cacgcgtaaa
     7081 attgaatagc atgaaggtgt atcatattaa cactgaacaa tttttcattg ctaatcagga
     7141 ttattcctca taagtagaac tcaagcagag aagccttggg ttctattttt ttgctctaaa
     7201 atcagattta ccaacagtcg gcaccagacg taaccgttta catcctctta cgaaaaccgt
     7261 atactgaatt taaatcaagt tgcacattga ggaggacttt agttttgaaa acgattaatt
     7321 taggtcacag caatattcaa gcttccagcg tggcacttgg catcatgcgc atggacgctt
     7381 tggacgtcgc ccaagccacc aaggttatcg ataccgctgc tgatttaggc atcaattacg
     7441 ttgattcagc tgatatctac ggtggtggtc aatcatcgac catcttcggt caagcactca
     7501 agcaggctca cgtatcgcgt gatcagctct atattcagtc aaaaggcggc attgttcctg
     7561 gcaagcgtta cgacttttcc aaacagcaca tactggcagc cgtggatggc gagcttcaac
     7621 gcttaggtgt tgattatctc gacaccttcc tcctccatcg accggacgcc ctgatggaac
     7681 ccgaagaagt tgctgccgct tttgacaagt tgcaaactag cggcaaggtg cgccactttg
     7741 gcgtctctaa cttcaatccc atgcaagttg acatgcttca agcggcacta aaccaacggc
     7801 tcatcatcaa ccaactccaa tttggtatca tgcataccgg tgcgatcgac tttggcttgc
     7861 acacgaacat gcaggacgaa cgtagtctta accacgacgg cgagatgatc gaatactcac
     7921 ggctccataa gatgacgatt caagcttggt cgccttatca atacggtaac ttcgcgggta
     7981 tcttcttaga caatccgaag tttccagaac ttaataatgc catgcaagca ctcgccgatg
     8041 agaaacaggt cactaaatca gctattgcga ccgcatggat tctccggcac ccagcccact
     8101 tccaagtcat ccttggtacg atgaatccgg aacatctagc tcaaaatgct gctggagcag
     8161 acgttacgct ttctcggcaa gaatggtacg acatttactt tgcagctggc aacgatttac
     8221 cttaatcacg atcgacctaa cagaattgac gattagtttt tacaatcaaa acgacgaccc
     8281 caaatcagga ttgattttca ggtcgtcgtt ttttagacgt ttcactaaca tttttgatgt
     8341 actcaccaca tctacgcgta tacttaatct taccaagact caggaggcga gcgaatgaca
     8401 tccacttgca cgatctgtga acgaatcaaa ctaattcagg cacatcagaa tccttatttc
     8461 gtttacgaac tcacaacggg ctacgtggtc cttgctgata gccagtactt tgaaggctac
     8521 acgctctttt tagccaaaca tcacgttacc gaattacatc atttaccggc acacgagaag
     8581 ttacgataac ttgaagagat gagtatcgtc caggaagctt gtgcgcaggc ctttcatgca
     8641 gacaaaatga acattgaact actcgggaat ggtgatgcgc atgttcattg gcacttattt
     8701 cctcgccata acggtgatac gcccaacccc ggtcccgtct ggtggacacc gctggaaaca
     8761 atttatggtg atgatgtcag tctagacatt ccccgtttaa gccggttgaa gcgcacgctc
     8821 agcgtagcaa ttgaggccac gcttaatgct cgggaagcag aattgcaggc tttagaggca
     8881 ctcacaaggc ctgctagcca cagaattgac agcaattaga ccaaatcagg acccagaccc
     8941 gcttagatct tggtggctac accccaattc ttaatcgcaa tccgtcaccg tatttcaaat
     9001 tgccaaaatc cacctattta tccggccgac tatcatacgc tcgcttagat ttatagccag
     9061 ctcgaaaaac cgtcttcata acttcaatgt gccgttcctt agttgcttgt gccttagttc
     9121 caaaaataaa gcgggcccat tcgcgctgat aaccaggtgt caaagccaca aagaacgttt
     9181 gcaattcagc atcaaccgct aacaattcgg ttaccgccgg aatatttttt tcaaatgaac
     9241 tgaggggtgc tgtactcata atcaaacctc cgattagttt tacttaaatt tactgtaaga
     9301 aagggaaaat ccctaatttt caggttttta tatttcgaat tttcataaaa ttgcgctatc
     9361 attatagtat aagtattatt atttgactac tataattaac catactgcta ttcaccaagg
     9421 ggagccctgc tatgccaaaa tttgatatca ccctcatcag tcccgaacgc gctaaagcga
     9481 tgttgactga atataaagaa caacgtaaga actctgtccc acatctggcc catcctggcc
     9541 gctatatctt gccggattac aaattaactc gtcgccgggc cgcattcaaa attgttaaac
     9601 ataccttttt aacgccccac tacaagtctt acgttgccat ggactctgac aacggccaca
     9661 cactctggtt tcataatttc ggttccctaa ccgaagcttt attctggtta gaaaccggcc
     9721 ttaaaatcag cgataccgac tcccattcta actacaagga atggatggct aagcacacta
     9781 cggaaatcga aaccttcaaa gacttgctgc gcgagcagaa gcataaacaa gggcccaaga
     9841 ctaagaaaaa agccaagtag cccgttttga cacctagatt cagataagca gcagtacgct
     9901 cattagcgtg ctgctgcttt tatttacgat caactgtgcc attcattact gactagacca
     9961 acctaaaagt ggctatccaa aaacgactgc agcttgcgta caatcacgcg atgaccggca
    10021 ttgttcggat gcaaagtatc caccgaataa atggccgctt gagcgggaat cgcaaatgtc
    10081 attcccgcat cacggtacaa gctcaaatgt gggacgccat agtctgcagt catctgggca
    10141 atcgctgctt cataatctga ctgacgatac ccgagaccat tagtcaccgc actaaaactg
    10201 cccccaaaat cagagccaat atgaattgct gaaataaata acttcggcac ggtcggccaa
    10261 ttcgtctgta atcccgtcag taacatcatt aacgcgccat aaaatgtcgt catatcgcaa
    10321 tcaccgtatt gccctaacgg ctgatcccga ccatagtcat tgacgccccc aaagacagca
    10381 ataaaatcag catcttcagg aatagcttga tagcgcaccg ccatcgcatc gtagcgactc
    10441 ccaatcgttg aaccagagat tcccaaatta tcgctccgct cgacatccca atcagccgcc
    10501 aaaatatcat gataatgcac cgtcgccaac ccattattcg ccgtaatcga atctcccaac
    10561 cacgccggcc gcttaaaact aacatgccca ttactaatcg ccatagccaa tcctcccttt
    10621 actatcatcg ctatcattct aatccatccc acctgaatta tggtagaaag atgcctttat
    10681 ttaaagtcaa cagccaccag cttaggcccg ctggaaacag ttccggttag cgtaaacctg
    10741 cttagttcgt tcgtcctacg ccgctctcca ggcatttctg ccaattgctg gaacgcggtg
    10801 gacacagatt taagtcgaag accacgtctt aaatactggt cttctactaa ccaagccaag
    10861 gacgcttgct aagtggaatt tcaccgctga gcattggccg aaacgccttc cattcgggac
    10921 agtattcgaa tggtggacga agatataccc aacttttgat gaatttgtca ttgttctcca
    10981 taaacagtaa ttttattaat caactgttag gtcgaaaaga tattgggata gctcgctatt
    11041 tcggaattac tatagtaata atagaacacc tcaacaaagt ggttagggta accctaacgt
    11101 ctcgtttaaa gttccggtat caaaatagcc aacgaccaat tgtgccgagt taagtggccg
    11161 ttcatcagcc attcgagcgg cttaccgaaa cgtgttcggt gccactaaag tctgtgcttg
    11221 ctatgccaac ggacaaatgc ccaaaccgca ttaatccgtt ggctagacaa tgctcggctt
    11281 caacccgtgg cttgagactg gaggggctgg gtgacaatgc tcagtagcca aattattctt
    11341 agtcggaagt gatttccttc cggcttagaa taagactcgt atttgagatg acgcgggtta
    11401 tgcgttagct caaatcgatg tcggctgcgt tccagcaatt gtcacccagc cccggaggtc
    11461 ggaataggac gctcaccggc tgacgaacag aaaaccaacc ctaaaaggca tctttctacc
    11521 attatttcaa acaggtgggc caatcttaaa aggctcgtat tatggaaatc cataatacga
    11581 gcctagttta attgatatat ttagttcaac tgagtagcgc taatcggctt ccgtttcacg
    11641 tttccgtgca gtacgccgtt cgcgtgcgta gtcagtttta gttgtgattt caacgtcacg
    11701 tgctagccgt ttccggcgtg ctaattcagc tgctttggca ttggctttcg cagcttcctt
    11761 gactggatca gtcgttaagt cgtgatggat cgagtacagt aagacgagcg cgacaatcgt
    11821 taatgggaag ccagacatcg cacagatgga ctgaatcgat tcaaagccac cgaccgtgac
    11881 aagccccaat gagaagacta ggaagataac gacccagctc atccgattga aacgacttgg
    11941 ttgttccccc gcggccaact ttttactagt aaatgacgag gtaatgaagg caaatgaaga
    12001 taccgtcgtt gctaagaaaa taaagcaaga taggcagtac aaagccagca taatcatctt
    12061 caatggtaag gtcgacaata ctgctgcaat cacagcggct tgtccttgcg tatttaagat
    12121 atgaactaag ttaacgatgc ccatccgttg caagtataag gcataaccac ccaagatggc
    12181 gtagaaactg acacaaccta atgagcccca tagcaacata ccaccgagta cctgacgaat
    12241 cgtccggccc cgagaaatcc gggcaatgaa taagcccatg actggcataa aggataacca
    12301 ccagccccag tagaagatcg tctgccgttg catggccgtt gcgtgaccat ttggtgcagt
    12361 attcgtgctc aacgtaataa acttattgac aaacaagcca atactattag tttctgagtt
    12421 taaaatatac aaagttgggc caacaattaa aacaacgatt aagaagccaa tcgctaacca
    12481 aacatgggca gcacttagtc gaccgatccc cttcttcaag ccattgaaaa cagccatggc
    12541 gaagattacg aataataagg caaataaccc taactttaaa gtcatcgtat cggcaatccc
    12601 ggtaacggca ctcaaaactt ttgaaatgac agggatttcc atcccgactg aagtaccaac
    12661 accacccata atcccaataa taacgagaaa atcaatcgtg ttccgggcaa tttgcttacc
    12721 cttaccagga ccttgtagta ctgaaattgc ggcactgagc cgctgaacct tgatgtgttt
    12781 aacatacatt gcataggcaa ttgcaatcgt ggctggcgca aacatcatcc acgccattgg
    12841 tccccaatta aattgtccca gcatgtgcgc ataattatat gcagaaattg aaaacggctt
    12901 gacgccgaat gaagggcttt ggaggtaccg taacgggtca accatgctca acattaaaat
    12961 gctggcatcg atcccggtcg cgtaaaccat actgccccag tgatacgttg aaaattctgg
    13021 tttgtcatca ggatcaccaa gtttggtttt ccctaactta ctaaacccta agtaaatgaa
    13081 aaagataaaa gtgatcacat ataccgacat ataaagccag ctcatgttat ttgtgagcca
    13141 gttcaagatg ccacttaaac tcgtctccag cgaatggccc cccattaata aaacaacgga
    13201 agccgccgca aagagcccaa ttgttggtaa atagacccac caatcaatat tcttactttt
    13261 taaaataata aacctgctac tgagcatata ctctctatat ttagatcaaa ttcgtggttc
    13321 ttcctaccag caatggtagt ccccacgcgt aaatttccga ctagcaatcg gtacacccct
    13381 ccgagttaat cctcggagca ctcagcaccc tgactgtatc aggtttgacc ggcattgtca
    13441 tccgcattct gtttgtgcta actcaaaatc agtagcagaa tttccttctt tccgttggtt
    13501 gaatccggac aacgccatac tgacaaatga tttttaattg cttaatcgac gttggtgttc
    13561 atcttgttta gctagtgttt ctattaccat cgtgccttta gcacacgacc gtcgtcacac
    13621 cacgtaacga ttaatggtta cactgctctt gctaatagat aacccccttg aatcaccaga
    13681 taagcccacc gcacaactgt tagattaatt gcttggtgca ccaaaaaagc gcttagtacc
    13741 gggtaacaag ttaccacctg cacagcgcac gttggcttat acaaatgctg atttcagtat
    13801 tttctgatat ctgatgttcg tttataagta tactagtatt aaatcagaag taaaatcaac
    13861 cattttgagc cgtcgaggcc taacccgtca aggattagac gagttttaca cccatatttt
    13921 ttctgaaact ttttaaaagt tttcgtaata attagttttt agtttagaat cattcttatc
    13981 tgtttcaatt aaaccgattt catgttattc ttgtaacaag ttaaaaaacg ttatcatcta
    14041 aaaggagggg aactgcatgc ggcactacta taaattaatt ttaacggtca gcgtcggtat
    14101 cattgcggtt gttttacagt ttggtttgca ctaccaattg gcagcacaaa tcatcattac
    14161 attaatgggg tcacttatgg ccttatcaat gttagttgag atgatcaaaa ccttacgttc
    14221 aggtaagtac ggggttgatt tattagcaat tacggcgatt gtggcaacac tagctgtcgg
    14281 cgaatattgg gctagccttg tcgttctaat tatgctcact gggggtgact cgttagaaga
    14341 ttatgcggcc aaacgagcga ataccgaatt gaaagccttg ctcgataatt caccacgtat
    14401 tgcccaccgc tcagtcgccg gccaattaac agatattgcc gttgaagatg tccaaattgg
    14461 tgatcagcta gtcgtcaaac ctggtgagct agttccagta gacggtcacc ttattcaagg
    14521 aacggcactc tttgatgaat cttcattgac gggtgaatct aaaccagtcg acaagcacgt
    14581 tggcgatgac attatgtctg gtgcggtcaa cggcgatagt gccgttacaa tggttgttga
    14641 taaattagcc attgatagtc aataccaaca gttagtcaaa ttggttaaag aatccgaatc
    14701 acgaccagcc aaattcgtac ggctggccga tcgctatgca gtcccattca ccctggtagc
    14761 atacgtcatt gccggagtag cttgggcatt cagcggggat ccccaccgat ttgcagaagt
    14821 cctcgtagtg gcttcccctt gcccgctgat tctcgccgca cccgttgcac tcgtctcagg
    14881 gatgagccga actagtcgga acggaatcgt ggtcaagact gggaacatgt tggagaagtt
    14941 atctacggct aagtccgccg cgtttgataa gacggggacc attaccagtg gtcaattaac
    15001 agtcaaccaa attgttcctc agtctggttt tactgccgaa caaatcttgc acctcgcagc
    15061 gagcgctgaa caaaactcaa gtcatatcct ggcccgctca ctcgtcaagt atgcgagtgc
    15121 cactagcctc agcccggcaa cacaattagc agaagtaacg ggtaatgggg tcacggcaac
    15181 gattgagcag caacaggtca aagtgggcaa acttaaattc gtcgcaccga ctacaaccgc
    15241 caagccactt gctaccactg ctatctacgt cggcatcgat gaccagtacg cgggttacat
    15301 cacgtttatt gacaatgtcc gccccgaagc agccgccacg cttaaagcac tccacgctga
    15361 gggcgttcaa aacgtcatga tgcttactgg cgaccaacag gcaattgctg atcatattgc
    15421 cgccgatgtc ggtatcgata ccgttgctgc cgacctccta cccgcagata agattgccca
    15481 cttaaaggct gtaccagcgg ccgaacgccc cgttatcatg gttggtgatg gtgttaatga
    15541 cgcgccttcc ttggctgttg ctgacgtcgg cattgccatg ggcgcccatg gctcaactgc
    15601 tgctagtgaa tcggccgacg tcgtcatctt aaaagacgat ctcagtcgcg tggtcacggc
    15661 ggtgcgcatt gctaaagata ccatgcaagt ggctaaacaa gccgtttgga t
//
