LOCUS       gnlProkkaEPEMNGIC_114  12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EPEMNGIC_114.
ACCESSION   gnlProkkaEPEMNGIC_114
VERSION     gnlProkkaEPEMNGIC_114
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 05:05:10
            Original ID  :: gnl|Prokka|EPEMNGIC_114
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 68424
            Orig. end    :: 80575
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7151]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7151
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(1068..1289)
                     /locus_tag="ctg70_43"
                     /transl_table=11
                     /translation="MRIDIKHYLEVNHLTIYQVSKRSGYGYTTLHKSFNKPQSSSTSLN
                     LRDLDALARAQDKSMWEVLKELEEHYLE"
     CDS             1796..2983
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     2.1e-71. Score: 232.8. Matches aSDomain:
                     nrpspksdomains_ctg70_44_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 270.9; E-value: 3e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_44"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.3e-71, bitscore:
                     232.9, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1e-06, bitscore:
                     21.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILSRLNNNFAKLTPGGIREFDYQVNSIPGIIKLTLGEP
                     DFNVPAAMKQAAIDSINANDSHYAPGNGTLVLRQAIAHFMQDRYQLDYDPENEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSSDGFVLTPERLKS
                     VLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTVKSTSLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGFELINPQGAFYVFAKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIAVFINKED"
     aSDomain        1904..2956
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg70_44_Aminotran_1_2.1"
                     /evalue="2.10E-71"
                     /label="ctg70_44_Aminotran_1_2.1"
                     /locus_tag="ctg70_44"
                     /protein_end="387"
                     /protein_start="36"
                     /score="232.8"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPAAMKQAAIDSINANDSHYAPGNGTLVLRQAI
                     AHFMQDRYQLDYDPENEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSSDGFVLTPERLKSVLEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTV
                     KSTSLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGF
                     ELINPQGAFYVFAKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             2985..3980
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 297.3; E-value: 1.6e-90)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_45"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 5.9e-53, bitscore:
                     171.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITMPKLIDDAVELTADV
                     DGLVIQQRSKVPGDIYEKLHANGLKQIATRTAGFDMVDIKKANENGLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSIEIHTATIGIVGVGRIGGTLAKL
                     LHALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPASKGLLTANDFAM
                     MKPTAGLVNASRGPVVNTADLVTALKAGEIAAAALDTFEGEETVAAADRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMTILNGGKSPHEITL"
     CDS             4048..4476
                     /locus_tag="ctg70_46"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQVSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSN
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             4627..4812
                     /locus_tag="ctg70_47"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYIYLLLLFLWIAPFSDGSLPLDESLLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(5001..7151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 329.5; E-value:
                     6.6e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_48"
                     /sec_met_domain="Peptidase_C39 (E-value: 6.7e-39, bitscore:
                     125.8, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 6.5e-276, bitscore:
                     910.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYPHYVAQVDEADCGVAALAMILHNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVIPIQADLSLFDDPEITYPLIAHVIKDDLLHYCVVFKADQ
                     DYIYVADPDPATKVQKMTRDEFGRLWSGVSLLFSPAKGYTPQKEPLAGLMTMFRQLTNY
                     KKDISGIVIAALLITFISIVGSYYLQLIIDRFIPSKSINGLAILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGIVLFLYDRSLFLTTISTIPIYVIIIYAFNKRFAKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAVLVVQDRLSIGTLMAFNALLAFFISPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDTEKSNTNSRDQADLIGPINIQHVDYSYEYSRPILQDINLQIGCNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQSPQLFSGTIKDNL
                     LMGLDREVSAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALL
                     TSAHVLIFDESTSSLDPITEKRIVENLLEIEDRTMIFIAHRLSIAKKVNKVVVMRDGKI
                     IEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7427..7588)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_49"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYRKLNFNELSEVSGGWGVTPWSVAWQTGKVAYSLVKHRRSYYA
                     SYQDSPFH"
     CDS             complement(7630..7788)
                     /locus_tag="ctg70_50"
                     /transl_table=11
                     /translation="MIYRKLNFDELSKVSGGWSLSSQVNELVGDIINSIKKWTQSCYEG
                     YQDSPFH"
     CDS             complement(7790..7957)
                     /locus_tag="ctg70_51"
                     /transl_table=11
                     /translation="MMKILTTAELEGINGGFKHNIWYYYGWGRASCIGTQRRNPSAFLN
                     HPNFIVLGGN"
     CDS             complement(8184..8951)
                     /locus_tag="ctg70_52"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEAYLAILDIELDNQLSGIDVAEQIRKKAEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGKQIESIADRLRIDIDEAYARYQNYVSSNQKHHEKITYEPIRGVKRQVDL
                     ENLYYIESVKNTNRRLRIVGKDIRIEYHGELNQVDSKHLLKVNQSTLINPKAIQEFNRK
                     ERIVYFDANREIKVTVSYRKIKSLVDFLEKENP"
     CDS             complement(8959..9771)
                     /locus_tag="ctg70_53"
                     /transl_table=11
                     /translation="MLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCATGFINFVKSS
                     QQTQRQQQIIDKYQAQIANANQLNQQYNEIRRERHDTRNMLLSVQGYIRDHKDKEAEKL
                     LATFLQNDTVEKHYGEIDNALDKIKISGLHNLVKEKAYKIVEKGIPFSFEINAEIDELP
                     GSEIKIARIIGILMDNAIEATFKQAKPYIQFALLKHSPEVYELVIANSIEQKLNINTAL
                     KFEHSTKEGHQGIGLSNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             complement(9924..10271)
                     /locus_tag="ctg70_54"
                     /transl_table=11
                     /translation="MIHLTVGQGLTSSILNIIEIIFIYQLVTSDFSLGLVIIDFLAVLM
                     IIFFSIVFFMLGSLYPVLIVFYFWLVDRIKSNSYIVINSILAMCISIVMASLFDLVDHY
                     TYAFFYKERQI"
     CDS             complement(10426..10590)
                     /locus_tag="ctg70_55"
                     /transl_table=11
                     /translation="MVDLDLETKKNLVIINLFYIGLIALYCILHAGPLNFLVFLGMLVL
                     ANIAEFVVK"
     CDS             complement(10714..12108)
                     /locus_tag="ctg70_56"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLGLLVLVVGCMTIHQRHHFNKNVKIDNVSVGG
                     LTVKQALKKLQDNPQSPKIYVNNELVFTDKQSVAKFSSADEQKIKNALRSQYTFFPSSK
                     TKNIAIKPQNVNQDEVSKIDQAVSQKVTELNNGRKAPVDAYAVYENSRVQVKPAVGGTQ
                     YSLDGLHNKVENEIAGGTIYLRPVYKAPLSANSKTVQNEKAKLEELSKRSVTYQVQNKK
                     YQLNCGEIITRATYQNGKYHFDTGATNSKIDEINNTQATLGKSFEFKTHSGSVIKTTAA
                     GSYGWKISKKQAGKTLTNALIENKQTVNAKNDIYGKGYNQQGTGYNTTSNNGIGDTYAE
                     VSLADQHAWFYKNGKCVLSTDIVSGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVQYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFSDLHKN
                     EPVVIY"
ORIGIN
        1 gtcatatcaa ttaaatcaat tgccttgtca ggtaatgcgc gttgcggcat gtattgaaca
       61 gaataatcaa cagctgcttg aagaacgtca tctggtaatt ttacattgtg gtgacgttcg
      121 tataagtcac gaatgccttt aaggatagca accgtatcag ccttgcttgg agcgttaaca
      181 gtaacagaat tgaaccgccg tgccaatgct gcatccttca taattgtatt acggtattcg
      241 tcttgtgtag tagcaccgat aactgttagt tcaccacgag ataatgctgg cttaataatg
      301 tcagacatac ccttagaacc gctagcgtca ccagttgaac cagcaccaat aatttggtga
      361 atttcatcga agaagaggat aatgttccct gccttcttga cttcatcaac taatttttgc
      421 atgttttctt caaaactacc acgatattga gtacctgctt caaggccaga aatatcaata
      481 ctaataattt ccttatcctt aatagcagct ggtacgtcgc cagaaacaat tgcttgtgct
      541 aatccttcaa caacagcagt cttaccaaca ccagcgtccc caactaatac agggttgttc
      601 tttgtccgcc ggcttaaaat ttcagctgtt tcttggattt ccttgttccg cccaataaca
      661 gggtcaagtt catgttcacg tgcttcttga gttaagtttc gacctaactt gtgtaagata
      721 ctatccttac cagcgttagg ttgagggcca ggttggccac cttgttgagg atttgcaccg
      781 cctggcaatt gaccagttct acgatattca gcaaattctt ctggtgttac ttcacgacca
      841 ttgattaggt aacgccgatt atcagaattg aaaccattca tgccacccat taattgatta
      901 aagatgtcat tcatgtcgtt gtcaaatgga ttcattgggt tttgagccat atgcaatccc
      961 tcctcaatta aatataatat tttgttttct aagtttcgta gtctaagtat tctagaagtt
     1021 aaaagttaac gcatttaact tcctatggct acagcaaagc cacaatctca ttcgaggtaa
     1081 tgctcttcta gttctttaag gacctcccac atgctcttgt cctgagcacg agccaaggca
     1141 tcaagatcac gcaggttaag cgaggtcgaa ctagactgtg gtttgttaaa cgatttgtgt
     1201 aaagtcgtgt agccgtaacc ggaacgcttg gaaacttgat aaatggtcaa gtggttaact
     1261 tccaaataat gtttgatgtc gatccgcatt gctacccact tcctttacga ttaatattat
     1321 atcacatttg tggagtaata caacaaaaaa gacaccaaaa aaattaaaaa aattgtagaa
     1381 tataaattta atattaaatt aaaggcgaaa taataatcac aaacattttt gagctttatt
     1441 atatttacat ttgtcattaa taaataattt tgtaattaat aatttttctc aatcaaccct
     1501 tgacaaagat taaaaaataa ttagaataat taataatcag ttaatcaaaa ggaggacaca
     1561 atgatgagca ctgcgacaat tcacttgaat caagcgtatg tcttctggtt tagcgcgatt
     1621 accgtccgct aaccagcagt gattttatca ttgtgatgtt cccggatgac ccccaaacat
     1681 ccgagagcct cttttatact cattccaatc tgatcaagaa gccctggatg tttttcctat
     1741 agcattcagg gcttcttttt ttctaaatct acatattata taggaggaat ttatcatgcc
     1801 aactactaaa aaagaaatcc ttagtcgtct taacaataat ttcgctaaac tcactcctgg
     1861 tggaatccgc gaatttgatt atcaggtaaa ctcaatccct ggcatcatta aactaacatt
     1921 aggtgaacca gactttaatg tgccagccgc aatgaagcag gccgcaattg atagcatcaa
     1981 tgccaatgat tcacactatg ctccgggaaa tgggacctta gtactccgtc aagcaatcgc
     2041 tcacttcatg caagatcgtt accagcttga ctacgatcca gaaaacgaaa ttgcggttac
     2101 agttggcgca acagaaggaa ttttcgcttc tctttcaact attattaatc ctggcgacga
     2161 aattatcatt ccaaccccaa ctttcccctt ctacatggct gtcacaaaga ttcttggtgg
     2221 aatcccgatt gaagttgata caagcagcga tggttttgtc ctcacaccag aaagactcaa
     2281 aagcgtacta gaagaacatc ctaacgccaa gggactagtt cttaactacc cctctaaccc
     2341 aactggtgtt acttacaccc aagatcaaat taaagcacta gctgatacgg ttaaatcaac
     2401 tagcctgatt gtaattgccg atgaaattta ctctgaactt gtttatggag ctactcatac
     2461 ttccatcgct aattacatcc ccgaacaaac gctaatttta aatggtgcct caaagtcaca
     2521 tgcaatgact ggttaccgaa tcggttttat cgctggtccg caagaattga tgaaatcggt
     2581 cagtgccatt cacgcgatgt tagtgaccgc tgcttctaat ccagcaatgg ccgctgcagt
     2641 cgccgcattt ggtactgacg aaggaaaaac agctactcaa gaaatgaaag atgcttatga
     2701 gcaacgacga gactttgttg ttaataacct ccaaaaatta gggttcgagc tgattaatcc
     2761 tcaaggagcc ttctacgttt ttgccaagat tcctgaacaa tatggtaatg atgaccttaa
     2821 atttgcgaca gatcttgcca atgaaggaaa agttgctgtg attcctggtt ccttctttgg
     2881 agctggcggc caaggatatg ttcgaattag ttacgccacc agtatggaaa atctaaccgg
     2941 agctcttgat aacattgcgg tcttcattaa taaggaggat taacatgacg aaaatcttga
     3001 tgactagtgt gcgggatgat gaacaaaccg ccattaatga atacgcaaaa gaacataata
     3061 tcgaaatcat cacaatgccg aaattgattg acgatgctgt tgaattaacg gccgatgttg
     3121 atggactcgt gattcagcaa cgcagtaaag ttccgggtga tatttatgaa aagctacatg
     3181 ccaatgggct caaacagatt gcgactcgga cagctggttt tgacatggtc gacatcaaaa
     3241 aggctaatga aaatggctta gtcgtaacca atgtaccagc atactcaccg cggagtgtcg
     3301 ccgagtttgc attaatgcag attttccggt tgcttcggaa aacttaccgc tttgatcacc
     3361 aagtcgccga aaatgacttc cgctggttta gcgatgaaca atcaattgaa attcatactg
     3421 ccacgattgg gattgttggt gttggacgca ttggcggaac cctggcaaag cttcttcatg
     3481 cattaggtgc taccgttcta ggatatgaca cgaatccgcg cactgacctc gatggaattg
     3541 tccagttcgt ttctaaagaa gaattactaa agcaagccga tgttgttagt ctccacgtcg
     3601 atttaaaccc agcttccaaa ggattgttga ctgctaacga ctttgcaatg atgaaaccaa
     3661 ctgctggttt ggtcaatgct agtcgtggtc cagtcgttaa tacggctgac ctcgtcacag
     3721 cattaaaagc tggtgaaatc gccgcggccg ccctcgatac ctttgaaggt gaagaaacag
     3781 ttgcagctgc ggaccgccga gaaaaaggac ttgatgatca gccccttgtt aaagaattac
     3841 acgaaatgga taatgtcatt cttactcccc acattgcctt ctttactaat ttagcagtca
     3901 aaaatatggt ggatatttca cttgatgatg tgatgacaat ccttaatgga ggaaaatcac
     3961 cacatgaaat caccttataa ttgagcaccc tcattgacca aaagtatcgt ctcgattaca
     4021 ctatgggtat taaaggaggg cacggttatg agtaaatata aagtaacagc aactaagaca
     4081 acaacgggga tgcaagtttc agcaggtacc cgtggttttg aaattacctt tgatgaacca
     4141 gaaagtacta atacggggat gaatccagta gaaattctcc ttgcatcatt tggtgcctgc
     4201 caggcaatca ctgcccaagc attagctaaa aagcgtaact ttgatttacg agctttttgg
     4261 gtaacaatcg agggtgatct tggtcgtgaa gacgttgctg atggtaaaaa tgttcgtaag
     4321 tttactgaga tccgttacca accacaccta cgcagcaacg agtctgatga agacatcaag
     4381 aagtttctcg ctgacgttgc cgcaaagtgt cccgtggaga acaccctgac ctacggaaca
     4441 aaatttgttc aagatggatt tgtaaaagtt gattagttga aaaaacgtct taggagtttc
     4501 caaggcgttt ttttaatagt taacctatac gaattctgca agaaacttaa cgaattttgc
     4561 aaagtgtcct ttaaattaga tctttcatta taataaggta cacatactgt cttaggggga
     4621 gaactaatga aaattcattt caataaggac ttttggcggg atggtttctt ttatatatac
     4681 ttattacttt tgtttctctg gattgcacca ttttcagatg gttcgcttcc attagatgag
     4741 tcgctactat gtatcttctt tataattttt actatcggtt cgatgctcgc aattatgttt
     4801 aataaagact gaaaaagaga gtgggaaata acctcctcga caaggcggtt ggctaagcta
     4861 ggacgatgat tagcacggca cgggctgatt atcgttcgta cttagactcg agccttgtgg
     4921 ttattttcca cgttatcttt ctattgttca taacaagtag ttggggctga gagaaaacaa
     4981 aagttttctc ccagcctctt ttatgcattc cacaaattat agtattcttg atgatgattc
     5041 aaaagttcct ggtgagtacc ctgttcaatg atttttccgt cgcgcattac taccacttta
     5101 ttgactttct tagcaatcga aagacggtgg gcaataaaaa tcattgtgcg gtcttcaatt
     5161 tcaagcaaat tctcaacgat tcttttttca gtaattggat ctaagctact tgttgattca
     5221 tcgaaaatta aaacatgcgc agaagttagg agtgctcgtg caatcgtcaa gcgttgtttt
     5281 tgaccaccag ataatgcagt tgcttcttca tctagttttg tttcatattt taagggcatc
     5341 tcttgaatat cattatagat taacgccaat ttacatgcat tatcgatttc ttcagcagat
     5401 acttcacggt ctaatcccat tagcaagttg tctttgattg ttcccgaaaa taattgtggt
     5461 gattgaggta agtaatgtac atattgtcta atatcgcaaa gattaatctc tgttgtttta
     5521 tgctgattaa attctatctg cccttgagtg ggtaaataaa aaccaactaa caactttgcc
     5581 aaggtcgatt taccagaacc gctcaaccct acaattgcca atttgtcatt acaaccaatt
     5641 tgaagattga tatcttgtaa aattgggcga ctatattcat atgaatagtc aacatgttga
     5701 atgtttatag gccctattaa atctgcttga tcccgagaat ttgtattcga cttttcggtg
     5761 tcaacttgca gcacttcatt caatcgatta ttcgctactt tagcttcttg gagtttaggt
     5821 tgaagattaa taatattttg caatggactg ataaaaaagg ctaataacgc attaaaggcc
     5881 atcaatgtcc caatactcaa tctatcttga actactaaaa ccgccccttg aaaaagaatg
     5941 attgttacta aaccgtattg aatccacatt ttaatcgcat cctgaaaaga tttagtttta
     6001 acatatgtta gattctttcg taagaaatcc gcaaattgtt tttcaacatt tttataacgg
     6061 atattttcaa gttgcagcac tttcaatgtc tctacgcctt ttaaatcctc aataatggca
     6121 gaacttaatt gagcattact ttccatctgt tcctgatcaa gtttagcaaa ccgcttatta
     6181 aaggcataaa taataatgac ataaatcgga atggtactaa ttgtagttaa aaataatgac
     6241 cgatcataca agaagagaac aattccaata atcaccatca cgccaacgtc taagaacatt
     6301 gaaataatag tgcttgataa ggcatcaata atcttattaa tgtcattaaa ccgcgaagta
     6361 atttcccccg tttttcttgt ggagaaaaat ctcatcggta aacgataaac atggtgaata
     6421 tatctaagac ttatttgtga cgttagtttt tgatccagcc tagtcaagag aacatctcgc
     6481 agataattaa aaagagaatt aaacacataa actactaata aactaccagc aagaatcgct
     6541 aagccattaa tacttttcga gggaataaac cgatcaataa ttaattggag atagtatgaa
     6601 ccgacgatgc tgatgaaggt aattaataat gccgcaatga caattcctga tatatctttt
     6661 ttataattag ttaattgtcg aaacatcgtc attaatccag ctaaaggttc tttttgtggc
     6721 gtatatccct tagcaggcga aaaaagtaaa cttacacctg accataaacg accaaattca
     6781 tcccgcgtca ttttttgtac tttcgtagca ggatctggat cagctacata gatgtaatct
     6841 tgatcagcct taaaaacgac acagtaatga agtaaatcat ccttaatcac atgcgcaatc
     6901 aatgggtaag taatttcagg atcatcaaac aatgatagat ctgcttgaat gggaataacg
     6961 tctaatccaa gatgctttgc tgcttttaca agtcctaagg ctgtagttcc ttgcttagtt
     7021 gtccgtgcta agtcacgtaa ttttgcgatt ggataaacag acccaaaatt gtgcaaaatc
     7081 attgctaaag cggcgactcc gcaatctgcc tcatcaactt gagctacata atgaggataa
     7141 ttgattttca ttcaccttgc tttctaatta gacaaagaaa taaagtccaa aattaataat
     7201 tattctgggc tttatattct tataagatac tatttatttt taaataaaat tcgtagagct
     7261 gcgaaaatac caatgattgt gcaagctata catataattg tttcataaat gttacttgcc
     7321 ttgggaattg ctaagaccca gaagaatgta actataatat agatataaaa atcaagattg
     7381 gtgtaaaaat cgtggttaaa tttcataatc attaagttat aaactattag tgaaatggac
     7441 tatcctgata gctcgcataa tacgaacgcc gatgtttaac aagcgaataa gcaacttttc
     7501 ctgtttgcca cgcaacactc caaggagtaa ctccccatcc accagaaact tcgcttaatt
     7561 cattaaagtt caatttacgg taagtcattt taattacctc catctcaaaa taactatcct
     7621 ttattattcc taatgaaacg gactatcttg gtaaccttca taacaagatt gagtccattt
     7681 ctttatagaa ttaataatgt ctccaactag ttcattaacc tgcgaagata agctccatcc
     7741 accagaaact ttgcttaatt catcaaagtt caatttacgg taaatcattt taattacctc
     7801 ctaatacgat gaagttagga tgatttaaga atgcactagg gttgcgacgt tgtgttccaa
     7861 tgcatgatgc tcttccccaa ccatagtagt accaaatgtt atgcttaaat ccaccattga
     7921 ttccctcaag ttcagcagta gtaagaattt tcatcataat tactcctcct cgtaattatt
     7981 aattttaata aatcaagttt ttccctacct tgattacact attagtatat aggcaaaaaa
     8041 gcattttggg agtattttgc aaaattcgta aacctttctg cataattcgt agtaaaatcc
     8101 ttgaaaacgt ttactaaaat tgtttgacaa taaaaaagaa accacgacag ctttttgtca
     8161 cagtttcttt gaaaataaag tagttagggg ttttcctttt cgagaaaatc gactaatgat
     8221 tttatttttc gataactaac agttacttta atttctcgat tcgcatcaaa gtaaactata
     8281 cgttctttac gattaaattc ttggattgct ttaggattaa taagagtact ctgattaact
     8341 ttcaataagt gtttactatc aacttgattt agctcaccat gatactcaat tcgaatatcc
     8401 tttccaacga tccgtaaccg tcgatttgta ttttttactg attcaatata gtaaagattt
     8461 tccaaatcaa cttgtcgttt tacaccacga ataggttcat aagtaatttt ttcgtggtgt
     8521 ttttggttac tacttacata attctgatag cgagcatatg cttcatcaat atcaatccgg
     8581 agtcgatccg caatcgattc aatctgtttc ccctttgata tatagtcgaa tggctcaatt
     8641 cggcgcgaaa cagtataagg taaatattct tgataagcag ttacaaagat aatttcagca
     8701 aattcagctt ttttgcggat ctgctcagca acatcaatcc cactaagttg attgtctagc
     8761 tcaatgtcta aaatcgccaa ataagcctca tctttgatgc tatcaatcac ttcttgcgga
     8821 tcatttgtcc gcaaatataa ttctatgtca taactatttg gagtagcgtt aatcaatttt
     8881 cgctgagaaa ctagacgctc agtataatca gcttgataat catcattttc caaaataatt
     8941 acttttaaca ttttattctc actttccctg aataaaacaa gtcatcataa ttaccttatc
     9001 tttaacttcc gctgaaaaag aataatggtc atcattttct accaactggg tcacattcga
     9061 aaggccaatt ccttgatgcc cttctttagt cgaatgttca aatttcagtg cagtattaat
     9121 attaagtttt tgttcaatcg aattagcaat taccaattca taaacttctg gactatgctt
     9181 aagcaatgca aactgaatat atggtttagc ttgtttgaag gttgcttcaa ttgcattatc
     9241 cattaaaatt ccgataattc tagcaatttt tatttctgaa cccggcaact cgtcgatctc
     9301 agcattaatt tcaaacgaaa acggaatacc tttttctact attttataag ccttttcctt
     9361 aacaagatta tgcaagccag agattttaat cttatctaat gcattatcaa tttcaccata
     9421 atgcttttca actgtatcat tttgaagaaa cgttgctagc aatttttctg cttccttatc
     9481 tttgtgatca cgaatatagc cttgaacact gagaagcata ttgcgtgtat cgtgacgttc
     9541 acgccgaatc tcattgtatt gttggttcaa ttgattggcg ttggcaatct gtgcttggta
     9601 tttatcaatg atttgttgct gtcgttgcgt ttgctgactg cttttaacga aattaataaa
     9661 tccggttgca catactacga taattatcaa atacattatt aacaacagcg aggcatactt
     9721 atttgctacc ccgtcctttt cggcaatagc agttaaccac acataaagca tgaacaaaat
     9781 tgccgtaatt tgccataacc ctatcggtcg aggaaaatta attctaatcc atctcaattt
     9841 gggacgaact attttaattg ctaagattgc aactacaata gttatgatta aatcattaat
     9901 tggaataagc catcctaaaa gtgctatatc tgtctttcct tgtaaaaaaa cgcataagta
     9961 tagtgatcta ctaaatcgaa taaagatgcc attacaatac taatacacat cgcaagaata
    10021 ctatttataa ctatataaga attagatttt attctgtcaa ctaaccaaaa ataaaatact
    10081 ataagtactg ggtatagcga tcctaacata aaaaatacta ttgagaaaaa tataatcatc
    10141 aagacagcta aaaaatcaat tattactaat cctaatgaaa agtcgctagt taccaattga
    10201 tatataaata ttatttcaat aatatttaat atagatgacg ttaatccttg tcctacagtt
    10261 aaatgaatca tcttttaatc caatttaaaa ctgctctttc ccatgaacga ggacttttaa
    10321 aggcaagtga atacccccaa ccacctaata ctttagataa ttctttcctt gataaaaatt
    10381 tatatgattt ttttaacata attacctcca ataaataaca attacctatt taactacaaa
    10441 ttcagcaata ttagccaaaa ctaacattcc caaaaacact aaaaaattca gtggccctgc
    10501 atgcaaaata caatacaagg caatcaatcc gatataaaaa aggttaatga ttaccaaatt
    10561 tttcttcgtt tctaaatcca aatccaccat ataactaaca cctactttat ccatccctct
    10621 gataatgcaa aagaaataat aattgttaaa acaaagcaag caattgcaat cataattgcg
    10681 cgttcagcac tcgggcgcac aacttctcct cctttagtag ataaccacag gctcattttt
    10741 atgtaagtca ctaaaagctt gaccagctac gtctggatgc atgttaatac aaccatgcga
    10801 tccaccgcct ttagcaagat aagcctgttt tgaccaatcg tgacgccaac ttgcatcatg
    10861 aaatccacat ccactatcag taaatggtga ccaatattga actttgctag cgtatttcga
    10921 accatcatcg ttaaggcccc gaagaacaga cggtgtttgc tggtacatga tataccagac
    10981 acccttcggc gtctcgttat ctttgttatt ggtcccacta acaatgtcag tgctaagaac
    11041 acatttacca ttcttataga accacgcatg ttggtcggct agtgaaactt cagcgtaagt
    11101 gtcccctatg ccgttgttgc ttgtggtatt atacccagtt ccttgttgat tataaccctt
    11161 accataaata tcattttttg catttactgt ttgcttattt tcaatcaatg cattcgtaag
    11221 agtctttcca gcttgtttct tactgatctt ccaaccatat gaaccagcag ccgttgtttt
    11281 aatcactgat ccactgtgag ttttgaactc aaatgatttg ccaagagttg cttgggtatt
    11341 attaatttca tcaatctttg aattagttgc tccagtgtca aagtgatatt ttccattttg
    11401 atatgttgct ctggtaataa tctcaccaca atttaattga tactttttgt tttgtacttg
    11461 gtatgttaca gatcgttttg ataattcttc gagctttgct ttttcattct gaacagtttt
    11521 actatttgca gaaagcggag ctttgtatac tggcctcaag taaatagttc cgccagcaat
    11581 ctcattctca actttattat gcaaaccatc taaactgtat tgagtaccac caactgctgg
    11641 ttttacttgt actcggctat tttcgtatac agcgtaagca tcaacaggag cttttcgacc
    11701 attatttaat tctgttacct tttgactgac tgcttgatca atctttgata cttcatcttg
    11761 attaacattt tgaggcttaa tcgcaatgtt ctttgtctta gatgatggga agaaagtata
    11821 ctgactacgt aatgcatttt taattttttg ttcgtcagca ctactaaact ttgctactga
    11881 ttgcttatcc gtaaatacta actcattgtt aacataaatt tttggcgatt gtggattatc
    11941 ttgtaacttc tttaatgctt gcttaacagt caatccacca accgacacat tatcaatctt
    12001 aacgttctta ttaaaatgat gacgctggtg aatagtcatg cagccaacca ccagcactaa
    12061 taagcccaat gtgattatta ttagttgttt aatagatagt ttttgcataa aagtactcca
    12121 ataacatcca aatctttaag tataatttct a
//
