LOCUS       c00001_gnlPro..        23236 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BHKOGBNF_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 05:59:16
            Original ID  :: gnl|Prokka|BHKOGBNF_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1556110
            Orig. end    :: 1579346
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23236
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1566110:1569346]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13236
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..23236
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23236
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="5"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             311..1156
                     /locus_tag="ctg1_1607"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAAEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQDGQELPEEEIMRVVEEAHKTLKEKKADVPE
                     "
     CDS             1254..1703
                     /locus_tag="ctg1_1608"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEMMGTICGDDTILIICRTPEDTEGVKNRLLELL"
     CDS             1740..3470
                     /locus_tag="ctg1_1609"
                     /transl_table=11
                     /translation="LLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLELLDKFAGAEVESALKTYQ
                     EGYQRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQQISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKMSESVSNSYYLLEDA
                     TFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEIDQIENR
                     DSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELKSLYMEKSTFDTEFK
                     VRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     CDS             3645..4925
                     /locus_tag="ctg1_1610"
                     /transl_table=11
                     /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETSLSVNAQTPESSEAFTVKKDPHEIKVTGKKSGESELVYDLAGFPIKKTKVHVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEGEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLARFSSER
                     KTIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFD
                     IEIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVND
                     PTSGYGVHIEWMLSEAGIDIYGKEKAS"
     CDS             5201..6004
                     /locus_tag="ctg1_1611"
                     /transl_table=11
                     /translation="VEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLF
                     KEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHE
                     IGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEV
                     AWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     CDS             6313..6426
                     /locus_tag="ctg1_1612"
                     /transl_table=11
                     /translation="MKKKKARKREGFFLDFLFEVGGELFLLLFRCVHKLFI"
     CDS             complement(6469..7617)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1613"
                     /sec_met_domain="Oxidored_FMN (E-value: 6.3e-122, bitscore:
                     405.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIQTKEDDQMNPKYKPLFEPFTFKSGVTIDNRIAVAPMTHYASN
                     EDGTISEAELDYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLAQAI
                     QAQGAKAVVQIHHGGIECPSELVPQQDVVGPSDVFDNGKQIARALKEEEVENIVKAFGE
                     ATRRAIEAGFDGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKA
                     ASEHAKGAFLVGYRLSPEEPETPGLTMTETYTLVDALGDKELDYLHISLMDVNSKARRG
                     ADPTRTRMDLLNERVGNKVPLIAVGSIHSADDALAVIENGIPLVAMGREILVDPDWTVK
                     VKEGREKQIETVIKGTDKEKYHLPEPLWQAIVNTPGWVPYKD"
     CDS             8120..8416
                     /locus_tag="ctg1_1614"
                     /transl_table=11
                     /translation="VKQTVLLLFTALFLSGCSVASADDSVPRFTEEGKYIGSADPHTIA
                     VSLNGEETMIQVPKDKRDECESLPDQTHVLVKYTKKDNGTLQLEDIQLRKNSS"
     CDS             8442..9056
                     /locus_tag="ctg1_1615"
                     /transl_table=11
                     /translation="MLWRSLALCGLALTLAPCAQAAEPIEGKTVYIDAGHGGEDSGAVG
                     NGLFEKDINLAVSEHVTDKLKEEGANPVASRSDDHFLTLEERVAKASANQADLFVSIHV
                     NSGVASASGTETYFQSDYEGENSRRLASDIQSQLVSSLQTRDRGVKESDFYVITYSQMP
                     SVLAELGFITNSSDADKLGSEEYQQKAADAIVNGIDSYYDQ"
     CDS             9135..9866
                     /locus_tag="ctg1_1616"
                     /transl_table=11
                     /translation="MTKIFAHRGASGQFPENTMLAFEKGIEAGADGIELDVQLTKDGRI
                     VVIHDERLNRTTSLKGFVKDTTYDEVKTANAAAGHDQAYSDIKVPLLEDVLSWAVKKDF
                     LINIELKNSVIRYEGMEEKVLEAVKRFNVEDRVILSTFNHDSLALCARLAPHIERAVLT
                     SDVLYQADRYIASIPASGYHPKLNSPGVTDEVLKKMRNGLIKVRPYTVNRPEDMKRLIE
                     AGADGMFTDFPEKASALLKNE"
     CDS             10001..10354
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1617"
                     /sec_met_domain="Thiolase_N (E-value: 1.5e-39, bitscore:
                     133.9, seeds: 30, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKTVIVSAARTPFGKFGGVLKEVKAAELGGMVMKEALQRAGVSG
                     DDVEGNVMGMVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRA
                     QDADILVAGGWKA"
     CDS             10351..11181
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1618"
                     /sec_met_domain="Thiolase_N (E-value: 6.6e-54, bitscore:
                     180.9, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 8.8e-50, bitscore:
                     165.4, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGN
                     TAAKEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIR
                     RDTSLDQLAKLAPIYASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFS
                     TTGMPAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVN
                     VNGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQVH"
     CDS             11206..12069
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1619"
                     /sec_met_domain="HCDH (E-value: 1.1e-37, bitscore: 126.5,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1.3e-67, bitscore: 225.1,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKR
                     LKKQLARDAEKGKRTETEVKSVISRISISQTLEEAEHADIVIEAIAENMAAKTEMFKTL
                     DRICPPHTILASNTSSLPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEET
                     ALDVMALAEKMGKTAVEVNDFPGFVSNRVLLPMINEAIYCVYEGVAKPEAIDEVMKLGM
                     NHPMGPLALADFIGLDTCLSIMEVLHSGLGDSKYRPCPLLRKYVKAGWLGKKSGRGFYD
                     YEERTS"
     CDS             12097..13236
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1620"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.4e-56, bitscore:
                     186.7, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7e-28, bitscore:
                     94.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.1e-38, bitscore:
                     129.4, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGE
                     HGLMGIPVPEQYGGVGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQ
                     KMKYIPKLASGDHLGAFALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADI
                     YITFALTAPDQGRHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANL
                     LGKEGDGFHIAMANLNVGRIGIAAQALGIAEAALDHAIDYAKQRVQFGRPIAANQGISF
                     KLADMATRAEAARHLVYHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYG
                     YMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKYLLGGT"
     CDS             13270..14388
                     /locus_tag="ctg1_1621"
                     /transl_table=11
                     /translation="MEEKQHYSPGLDGVIAAETHISYLDTQSSQILIRGYDLIELSETK
                     SYLELVHLLLEGRLPEESEMETLERKINSASSLPADHLRLLELLPEDTHPMDSLRTGLS
                     ALAGYDRQIDDRSPSANKERAYQLLGKMPALTAASYRIINKKEPILPLQTLSYSANFLY
                     MMTGKLPSSLEEQIFDRSLVLYSEHEMPNSTFAARVIASTHSDLYGALTGAVASLKGNL
                     HGGANEAVMYLLLEAKTTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMMKEALQ
                     QLCDKAGDHRLYEMCEAGERLMEKEKGLYPNLDYYAAPVYWMLGIPIPLYTPIFFSART
                     SGLCAHVIEQHANNRLFRPRVSYMGPRYQTKP"
     CDS             14403..15821
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1622"
                     /sec_met_domain="MmgE_PrpD (E-value: 3.7e-151, bitscore:
                     501.5, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKTDRVIEEITDYVLEKEITSAEAYTTAGHVLLDTLGCGILALR
                     YPECTKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEWGH
                     PSDNLGGILAAADYVSRVRLSEGKEPLTVRDVLEMMIKAHEIQGVLALENSLNRVGLDH
                     VLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAGDATS
                     RGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLFKVSYPA
                     EFHAQTAAECAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRDHCLQYI
                     TAIGLLFGDITAQHYEAETASDSRIDKLRDKMEVTENKTYTEDYLKPDKRSISNAVQVH
                     FKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHFPDKQHKHIYERCTSYETL
                     QTMRVNEFVDMFCM"
     CDS             15838..16743
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1623"
                     /sec_met_domain="PEP_mutase (E-value: 1.3e-54, bitscore:
                     183.2, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKEA
                     GFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLNAA
                     RTAREMLEARVAAVQIEDQQLPKKCGHLNGKQLVPIKEMAQKIKAIKQAAPSLIVVART
                     DARAQEGLAAAIKRSEAYIEAGADAIFPEALQAENEFRQFAERIPVPLLANMTEFGKTP
                     YYRADEFEDMGFHMVIYPVTSLRAAAKACERMFGLMKEHGSQKEGLHDMQTRKELYDTI
                     SYYDYEALDKTIAKTVLPDE"
     CDS             complement(16785..17021)
                     /locus_tag="ctg1_1624"
                     /transl_table=11
                     /translation="MSRLLALLILVIPGAISALGIKLMRDTLFGHTIKPFSALWLQGLS
                     GFIFFAIGLYVLAGFILYRDRKRNQVSPRFRKR"
     CDS             17174..19252
                     /locus_tag="ctg1_1625"
                     /transl_table=11
                     /translation="MQKVLIVGAGKRGTALLHILIKTAIIDIIAVVDKDPEAPGLKEAE
                     QYGIAVSSDWKPYIQQKPDIVIHTTGDQAVFDKLLQRKHEDTIVMPGKMAYIVFQLMEE
                     KQHLIQMLKEQTYKYDRIFNSTHDGMIFIDINEEIILFNHMAEKMVGKKREEVIGRPIK
                     EVIPSTKMPRILKTRVPEYNQKQLLGDHLQIVTTRLPIIDEGGRLLGALCVFKDITDAV
                     ELAEEVTNLKQVRTMLEAIIQSSDEAISVVDENGIGLLINKAYTKMTGLSEKEVIGKPA
                     NTDISEGESMHLKVLETRRPVRGVRMKVGPNEKEVIVNVAPVIVDGILKGSVGVIHDVS
                     EIKMLTAELNRARQIIRTLEAKYTFDDIIGKSEQMLVALEQAKLGAKTPATILLRGESG
                     TGKELFAHAIHNESDRKYNKFIRVNCAALSENLLESELFGYEDGAFSGAKRGGKKGLFE
                     EANNGSIFLDEIGELTQNMQAKLLRVLQEKEIVRVGGTKAIPVNVRVIAATNVNIEKAM
                     ADGTFREDLYYRINRYPISIPPLRQRLEDIEALSVRLIQKINRDYGRNVKGLSQQALRA
                     LSAYHWPGNVRELENVLGRAMIFLNPHMEWIEKDHLPVFELEQKENDTDQGTGFDFPDI
                     EGEKLSVAVEKFEAHLIQQTLEKHHFNRTKTAKALGVSIRNLYYKMDKYGLANEGMQ"
     CDS             19377..20276
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1626"
                     /sec_met_domain="PTA_PTB (E-value: 1.6e-48, bitscore:
                     163.6, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLL
                     TGDSTKLNELTSSMQGHQVEIVHADTPEESANLAVRAVHHKTADVLMKGNVPTSVLLKA
                     VLNRQEGLRSASVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVAHAV
                     GNNMPKAAALAAVETVNLKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQIAAA
                     QKKISGDVAGNADILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSAE
                     NKLYSIALAICASEEYTH"
     CDS             20288..21382
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1627"
                     /sec_met_domain="ELFV_dehydrog (E-value: 4e-10, bitscore:
                     37.7, seeds: 97, tool: rule-based-clusters)"
                     /sec_met_domain="ELFV_dehydrog_N (E-value: 4.6e-29,
                     bitscore: 98.9, seeds: 410, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELFKYMEKYDYEQLVFCQDEQSGLKAIIAIHDTTLGPALGGTRM
                     WTYENEEAAIEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEEMFRAFGRYIQ
                     GLNGRYITAEDVGTTVEDMDIIHDETDYVTGISPAFGSSGNPSPVTAYGVYRGMKAAAK
                     AAFGTDSLEGKTIAVQGVGNVAYNLCRHLHEEGANLIVTDINKQSVQRAVEDFGARAVD
                     PDDIYSQDCDIYAPCALGATINDDTIKQLKAKVIAGAANNQLKETRHGDQIHEMGIVYA
                     PDYVINAGGVINVADELYGYNAERALKKVEGIYGNIERVLEISQRDGIPAYLAADRLAE
                     ERIERMRRSRSQFLQNGHSVLSRR"
     CDS             21407..22492
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Butyrate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1628"
                     /sec_met_domain="Butyrate_kinase (E-value: 4.3e-153,
                     bitscore: 507.0, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLHDEKRILTINPGSTSTKIGVFHNERSIFEKTLRHNIEELQRFD
                     RIIDQYEFRKNHILETLHEQGINISKFDAVCARGGLLRPIEGGTYVVNDDMIEDLKSGY
                     AGQHASNLGGIIAREIADGLNIPSYIVDPVVVDEMSVLAKVSGMPEIERKSIFHALNQK
                     AVARKAAASLGKRYENMKMIITHMGGGITIGVHDRGRVVDVNNGLHGEGPFSPERAGTV
                     PAGDLVDLCFSGEYTKEEIMKKLVGTGGLLGYLGTNDAVKVEQMIQGGDEKARFIYDAM
                     AYQVAKEIGAASAALKGEVEAIVLTGGLAYGKSFVSAIRSYIDWISDVLVYPGENELQS
                     LAQGALRVLQGEEQSKQYRIE"
ORIGIN
        1 tgcgcgttgt gaatgcgcgt tttattaagc cgattgatga aaagatgatg aagagtatcc
       61 taaaagaagg cttgccaatt ttaacaattg aagaagcggt cttagaaggc ggtttcggaa
      121 gctcgatttt agaattcgct catgatcaag gtgaatatca tactccgatc gacagaatgg
      181 gtatacctga tcggtttatt gaacacggaa gcgtaacggc gcttcttaag gaaattggac
      241 tgacaaaaca gcaggtggca aatcgtatta gattactgat gccgtcaaag acacacaaag
      301 gaattggatc atgacgtcaa agaaagaacg attagatgta ttattagtgg aaagagggct
      361 ggcggaaacg cgtgaaaaag ccaaaagagc cattatggcg gggatcgtct attcaaacga
      421 aaaccgcttg gacaagcctg gagaaaaaat tgaccgcgac cttccgttaa ccgttaaagg
      481 aaacccgctg aggtatgtga gcaggggcgg cttaaagctc gaaaaagcgt tgaaggaatt
      541 tcccgtctct gtcaaggata aaattatgat tgatattggc tcctccaccg gcggttttac
      601 ggactgcgct ttgcaaaatg gagctaaaca gtcatacgct gtggatgtag gctataatca
      661 gcttgcgtgg aagctcagac aggatgaacg ggtcgtcgtg atggaacgga cgaactttcg
      721 ttatgcaaca ccggcagact ttacaaaggg catgccggag tttgccacaa ttgatgtgtc
      781 ctttatttca ctgcggctca tcctgcctgt cctaaggact ttgctcgtac cgggcagcga
      841 ctgcatggct ctagttaagc ctcagtttga agcgggacgg gaatccgtcg gcaaaaaagg
      901 gattgtcaga gatcctaaag tgcatgctga tgtgctcaag cgaatgatca gtttttctgc
      961 cgctgaaggc tatatatgta aaggcttgtc attttctcca atcactggag gagacggaaa
     1021 tattgagttt ctccttcatt tgcattggcc gggagaggga caggatggcc aggagctgcc
     1081 ggaagaagag atcatgcgcg ttgtagaaga agcacataag acgttaaaag aaaaaaaagc
     1141 agatgtaccg gaataatagg gcgctattat tccttttttc tgcattcatg tacaatgtgc
     1201 agagaatcat ataacataaa agaacagata agcttggaaa tagaggtgct tacatgaaca
     1261 aaggccagag gcatattaaa atcagagaga tcattacaag caatgaaatc gaaacgcagg
     1321 atgaattggt cgacatgctg aagcaggatg gatacaaagt aacgcaggcc acggtatcac
     1381 gggatattaa agaacttcac cttgtaaaag tgcctacaaa taatggttct tacaaataca
     1441 gtcttccggc ggaccagcgt ttcaatccgc tgtcaaagct aaagcgggca ttgatggacg
     1501 catttgtgaa aatagactca gcaagccata tgattgtgct gaaaacgatg ccgggcaatg
     1561 cccaggcaat cggggcgctg atggacaatt tggactggga tgaaatgatg gggaccattt
     1621 gcggagatga tacgatttta attatttgcc ggactcctga agatacagaa ggcgtaaaaa
     1681 acaggctcct tgaactgctg taacagaaaa tctaacaaag ataagaggtg taatgctgtt
     1741 tgttagctga actatcgatt aaaaactttg ccattattga ggaactgacg gtttcttttg
     1801 aacgcgggct tacggtttta acaggagaaa ccggagccgg caaatccatc atcatagatg
     1861 ccatttctct tttagtcgga ggccgcggat catctgaatt tgttagatat ggggaagcaa
     1921 aagccgaact tgaagggctg tttctgttgg agagcggcca tcctgtttta ggcgtatgcg
     1981 ctgagcaggg aatcgacgtt tcagacgaaa tgatcgtcat gagaagggat atcagcacga
     2041 gcgggaaaag cgtttgccgt gtcaatggca agcttgtcac gattgcttcg ctaagagaga
     2101 tcggcaggct tttattagat attcacggac agcacgataa ccagctgtta atggaagacg
     2161 aaaatcatct cgagcttttg gacaagtttg ccggggccga agtggaaagc gcgctcaaaa
     2221 cgtatcagga aggataccag cggtatatga agctgctcaa aaagcttaag cagctttctg
     2281 aaagcgaaca ggaaatggcc catcgtcttg atcttattca atttcagctc gaagaaatcg
     2341 aatcggcaaa gcttgagctt aacgaagatg aacagctcca agaagagcgc cagcaaattt
     2401 caaactttga gaagatatat gagtcgctgc aaaatgcata taacgcgctt cgcagtgagc
     2461 agggcggatt ggactgggtt ggaatggcat cagcgcagct tgaagatata tctgatataa
     2521 acgaaccgct gaaaaaaatg tctgaaagtg tttcgaactc ctactatttg cttgaggatg
     2581 ccacatttca gatgagaaat atgctggatg agcttgaatt tgatccggaa cgcctgaact
     2641 atattgagac gcgacttaat gaaatcaaac agctgaaacg aaaatacggt gccactgttg
     2701 aagacatttt ggaatatgct tctaaaattg aagaagagat tgaccaaatt gaaaacaggg
     2761 acagccacct tcaaagcttg aaaaaggagc ttgactccgt cggcaaagat gtcgcagtgg
     2821 aagcggcaaa tgtgtcacaa atccgaaaaa catgggcgaa aaagctggct gatgagattc
     2881 atcgggaatt aaaaagcctg tacatggaaa aatcaacttt tgatacggaa tttaaggtca
     2941 gaacagcgtc acgcaatgaa gaggctccgc ttgtaaacgg ccagcccgtt cagctgactg
     3001 aacaagggat tgacctggtg aagtttttaa tttcgaccaa tacaggcgag ccgctgaaat
     3061 ccctttcgaa agtcgcttca ggtggagagc tgtcacgggt gatgcttgcc ataaaaagca
     3121 ttttttcttc acaacaggat gtgacatcga tcatttttga tgaggttgat accggtgtaa
     3181 gcggcagggt cgcacaggca atcgcagaga agatccataa ggtgtcaata ggatcacaag
     3241 tgctgtgcat tacacacctg cctcaggtgg ctgccatggc cgatacgcat ctttatattg
     3301 cgaaggagct aaaagacggc agaacgacga cacgtgtcaa gccgctctct aagcaggaaa
     3361 aggtagcgga aatcgggcgc atgattgcag gtgtcgaagt aaccgactta acgaaacgcc
     3421 atgcgaaaga acttttaaaa caagcggatc aagtcaaaac aactgggtaa gctgcgcgag
     3481 aagcgcagct tatttttttc gtgcacatcc attcgttcat cagtatatcc aatgtttttc
     3541 ttcatatgac agttataaat aagccgtcag aaggcaaaat taaatgatgt agcagcaagt
     3601 cataaagaag gtgtgggata ggagcgagga gagtgaagta gtgaatgccc gataacatca
     3661 gaaaagcagt aggtttaatt ctccttgttt cgttattaag tgtaggttta tgcaaaccgc
     3721 taaaagaata tttattgatt ccaacgcaaa tgagagtatt tgaaacccaa acacaagcga
     3781 ttgaaacaag tttatcggta aacgctcaga caccagaatc ctcagaagcg tttacagtaa
     3841 agaaagatcc gcatgaaatc aaggtgacgg gcaaaaaatc aggtgagtca gaattggtat
     3901 atgatcttgc cggatttcca attaaaaaaa caaaagtgca tgttcttcct gatttaaagg
     3961 ttatacctgg cggacaatca atcggtgtaa aacttcattc cgtcggtgtt cttgtcgtcg
     4021 gatttcatca aatcaataca agtgaaggca aaaaatctcc gggagaaacg gccggaattg
     4081 aagcgggcga catcattatt gagatgaatg gacagaaaat tgaaaaaatg aatgatgtag
     4141 ccccatttat tcaaaaggct gggaaaactg gtgaatcttt agatttactg atcaaacgtg
     4201 ataaacagaa aatcaaaacg aagctgatcc cagaaaagga tgaaggagaa ggcaaataca
     4261 gaatcgggtt atatatcaga gattctgctg ccggcatcgg cactatgacc ttttatgaac
     4321 cgaaaacaaa aaaatacgga gcacttggcc acgtgatttc cgatatggac acaaagaaac
     4381 caattgtagt ggagaatgga gaaatcgtta aatccactgt aacatcaatt gaaaaaggga
     4441 caggcggtaa tccgggagaa aaactggcgc gattttcctc agaacgcaaa acgatcgggg
     4501 atattaacag aaacagcccg tttgggattt tcggcacact gcatcagccg attcaaaaca
     4561 acatatcaga tcaagcattg ccggttgcgt tttctaccga agtcaaaaaa gggccggctg
     4621 aaattttaac cgttattgat gatgacaaag tagaaaaatt cgatattgaa atcgttagca
     4681 caacgccgca aaaattccct gcgacaaaag gaatggtgtt gaaaattacc gatccaaggc
     4741 tgttgaaaga aacaggaggc atcgtacagg ggatgagcgg aagtccgatt attcaaaatg
     4801 gaaaagtgat cggtgctgtc acccatgtat ttgtaaatga cccgacaagc ggctacggtg
     4861 ttcatattga atggatgctg tcagaagcag gaatcgatat ttacggaaaa gaaaaagcaa
     4921 gctgactgcc ggagtttccg gcagtttttt tattttgatc catcttcact tctcagaata
     4981 cataaggtaa aatatacaaa agaagatttt tcgacaaatt cacgtttcct tgtttgtcaa
     5041 atttcatttt tagtcgaaaa acagagaaaa acatagaata acaaagatat gccactaata
     5101 ttggtgatta tgattttttt agagggtata tagcggtttt gtcgaatgta aacatgtagc
     5161 aagggtgaat cctgttaact acatttgggg aggaagaaac gtggagaaaa ttaaagtttg
     5221 tgttgctgat gataatcgag agctggtaag cctgttaagt gaatatatag aaggacagga
     5281 agacatggaa gtgatcggcg ttgcttataa cggacaggaa tgcctgtcgc tgtttaaaga
     5341 aaaagatccc gatgtgctcg tattagatat tattatgccg catttagacg gacttgcggt
     5401 tttagagagg ctgagggaat cagatctgaa aaaacagccg aatgtcatta tgctgacagc
     5461 ctttgggcag gaagatgtca cgaaaaaggc cgtcgattta ggcgcgtcct actttattct
     5521 caaaccgttt gatatggaaa accttgtcgg tcatatccgc caggtcagcg gaaatgccag
     5581 cagtgtgacg catcgtgcgc catcatcgca aagcagtatt atacgcagca gccagcctga
     5641 accaaagaag aaaaatctcg acgcgagcat cacaagcatt atccatgaaa tcggcgtccc
     5701 agcccatatt aaaggctatc tctatctgcg cgaagcaatc tcaatggtat acaatgacat
     5761 cgaattgctc ggcagcatta caaaagtcct ctatccggac atcgccaaaa aatttaacac
     5821 aaccgcaagc cgtgtagaaa gagcgatccg tcatgcaatt gaagtggcat ggagcagagg
     5881 aaacattgat tccatttcct cgttgtttgg ttatactgtc agcatgacaa aagctaaacc
     5941 taccaacagt gaattcattg caatggttgc ggataagctg aggttagagc ataaggcttc
     6001 ttaaacatga gcttattaag tggtcattaa atcaaacgtc ttttatttat tagtttgcgc
     6061 tgataaatag gaggcgtttt gttttgggta catttgtagt atgggagaag aatattaagt
     6121 atccgcatat agtaaaggat aggtttgaaa agtaaggaaa gcaaatggcg gtattagctg
     6181 cactcttggt ccattcatac atcttatagg atcacgaagc atgatcgacc ctagatgtgt
     6241 ccgttataaa atgaaacctt tctcctgcaa aatcgtaagt aaggcgtatt catgtaaaaa
     6301 ggagacgtac gaatgaaaaa gaaaaaagca agaaagcgtg aggggttttt cctggatttt
     6361 cttttcgaag ttggtgggga gctctttctt ttgctgttta gatgtgtaca caaactattt
     6421 atataaaggg aaaaaagact gccgaatcgt ttcggcagtc tttgcacatt aatctttata
     6481 aggcacccag cctggcgtgt tcacaattgc ttgccatagc ggttcaggca aatgatattt
     6541 ttctttatct gtgcctttga tcactgtttc gatttgcttt tcacggcctt cttttacttt
     6601 taccgtccag tcagggtcaa ctagaatttc gcgtcccata gcgactagcg gaataccgtt
     6661 ttcgatgacg gcaagcgcgt catcagcgga atggatggaa ccgacggcga tcagcggcac
     6721 tttgtttccg acacgttcat tcaataagtc catgcgtgtg cgagtcggat ctgcaccgcg
     6781 gcgcgctttt gagttcacgt ccatcagtga gatatgaaga taatccaatt ctttatcccc
     6841 taaagcatca acaagcgtat aagtttcagt cattgtcaat cccggtgtct caggttcttc
     6901 cggagacaga cggtagccga ctaagaacgc acccttcgca tgttctgaag cggctttttt
     6961 cacttcatcg acaatagcga gcgggaaggc taatcgtttt tcatcgcttc ctccccagcg
     7021 atccgtgcgc tgattggttt tcggagaata aaactgctga attaagtagc cgtttgcacc
     7081 gtgaatttcg acaccgtcaa agccggcttc aatggcgcgt cttgtcgctt ctccaaaagc
     7141 cttcacaatg ttttccactt cttcttcttt taatgcgcga gcaatttgtt tgccgttatc
     7201 aaacacgtca cttggcccca caacatcctg ttgaggaacg agctcagacg ggcactcaat
     7261 accgccgtga tgaatttgta caacagcttt agcgccttgt gcctgaatgg cttgtgctaa
     7321 cttttttaaa cctggaatgt tggaatcgtc atggatggcc ggctgcccgg ggaatgcttt
     7381 tccgtccggt gtaacatttg cgcaggctgt aatcaccatt cccatctctt ttgaacgggg
     7441 gatgatgtag tcgagctccg cttcagatat tgtaccgtct tcattagaag cgtaatgagt
     7501 catcggtgct actgcgatcc ggttgtcgat tgtaacgccg cttttaaacg taaatggttc
     7561 aaaaagtggc ttatacttag gattcatttg atcatcttct ttcgtttgga ttcgcacata
     7621 ttctagccta tatgtaaaaa ttaatgcaat tgatctgctt taccgactga atatcttgag
     7681 tgcagagtga tgttttcgcc gctctttttc ggggcctttg tagccgccgc tgatttggtg
     7741 gccgatggag catgtgatga cagctgccgc cagcagcaga acgaattttt tcatggcttt
     7801 aacttctttc aataaagtaa atatccttta aaaggttacg cttggctgac ccacccgtca
     7861 aacgatttgc tcaccctatt ctcaaatttt ttaaaatgaa taaaaagttg cttctttccg
     7921 ctaatttttt ctaattggcg cctcaattag agccatcctc atagacaaat ctgctcgtta
     7981 tctttctaac aacaggaaat gatcgggtcg tatagccctt ttgaaaatca tggaacttgc
     8041 tcgcctgcat tcgcgttgtc tttacaaatt tgccattctg gtcaaagata aaagccaaac
     8101 atcaggaaga ggtggtcatg tgaaacaaac ggttcttttg ctgtttactg cgctctttct
     8161 ttcggggtgc agtgttgcaa gtgcggatga ctcagtgcca aggtttaccg aagagggaaa
     8221 atacattggc tcggctgatc ctcatacgat tgcggtttct cttaatggag aagaaaccat
     8281 gatacaagtt ccgaaggata aacgtgatga atgtgaatca ctgccagatc agacacatgt
     8341 cctggtgaaa tatacaaaga aggataatgg aactttacag ctggaagata ttcagctgcg
     8401 aaagaactcg tcataaaaag accggaggga gtaagttgag aatgttatgg aggagcttgg
     8461 cgctgtgcgg attggctttg acgctcgcgc cttgtgcaca ggcagcagag ccgatagaag
     8521 ggaaaacagt gtatattgat gccggacacg gcggtgaaga tagtggagcg gtcggaaacg
     8581 ggctctttga aaaggatatt aatttggctg tctcagagca tgtgacagac aaactaaaag
     8641 aggagggagc caatcctgtt gcatcccggt ctgacgatca ttttctgacc ttggaggaaa
     8701 gagtggctaa ggcaagtgcc aatcaggctg acctttttgt cagcattcat gtgaattcag
     8761 gggttgcttc agcttcagga acagaaacgt attttcaatc tgattatgaa ggggagaaca
     8821 gccggcgtct ggcatccgat attcagtcac agctcgtttc ttccttacaa acgagagaca
     8881 ggggcgtgaa agaatcagac ttttacgtca ttacatattc acaaatgcca agtgtgttgg
     8941 cggagcttgg gtttatcact aacagttctg atgcggacaa gctgggaagt gaagaatacc
     9001 agcaaaaggc cgcagatgcg attgtcaacg gcattgattc ttattatgat cagtagattg
     9061 atacagcctt aatcctagag tggagccgac aaaataagta taatggagaa aactttaggg
     9121 tttgaggtga aacgatgaca aagatttttg cccaccgggg ggcatcaggt caatttcccg
     9181 aaaatacaat gcttgcattt gaaaaaggaa ttgaagccgg agcggatggg atagagcttg
     9241 atgtacagct gacgaaagac ggacgcattg ttgtgattca tgatgaaaga cttaatcgca
     9301 cgacatcact taaaggattc gtgaaggata caacctatga tgaggtaaag actgcgaatg
     9361 cggccgctgg tcacgatcaa gcgtacagcg atataaaagt gccgctgcta gaagatgtgc
     9421 tctcgtgggc ggtaaaaaag gattttctca tcaacattga attaaaaaac agcgtgatcc
     9481 gctatgaggg aatggaagaa aaagtgctgg aggcagtgaa gcgattcaat gtagaggaca
     9541 gagtcatcct atccaccttt aatcatgaca gcttggcgct atgcgcccgg cttgcgccgc
     9601 atatcgaacg ggcagtatta acttcagatg tgctttatca ggcagatcga tatatcgcgt
     9661 ctattccggc ttccggctat cacccgaagc taaacagccc aggggtcaca gatgaagtac
     9721 tgaagaaaat gaggaacggt ttgattaagg taaggccgta tacagtcaat cgtccggaag
     9781 atatgaagcg tctcattgaa gcgggagcag acggcatgtt taccgacttt ccagaaaagg
     9841 cttcggcatt gctgaaaaat gaatagttgt tagaaggagg ctgtttgacg cagccttctt
     9901 ttttcattca ttcattcatt catgcccgtt tcaaagcata cattcataga agacaactag
     9961 aaattgtaag cgctgtctat cttctgaatg aggtgaaacc atgaggaaaa cagtcattgt
    10021 aagtgctgca agaacgccat ttggcaaatt cggcggagta ttgaaagagg tgaaagctgc
    10081 tgagcttggg ggcatggtga tgaaggaggc gctgcaacgg gctggagtct ctggagatga
    10141 tgtagaagga aacgtcatgg gcatggttgt ccaggccggc tcagggcaga taccttcccg
    10201 tcaagctgcc cgtctggcgg gaatgccttg gagtgtgccg tcagaaacac tgaataaagt
    10261 ctgtgcttcc ggccttcgcg ctgtcacttt atgtgatcaa atgattcggg cgcaggatgc
    10321 ggacatactt gttgcggggg gatggaaagc atgagcaata ttccgtatgc cgttcccgcc
    10381 gggcgctggg gagcacggat gggggacggc gagcttaggg acttaatggt gtatgacgga
    10441 ttaacgtgcg catttgacga ggtgcacatg gctgttcacg gaaatacagc tgccaaggaa
    10501 tatgcaatct cacgaagaga gcaggacgaa tgggcgttga gaagtcatgc aagggcagct
    10561 aaggccgccg atgaagggaa gtttcaggat gaaattgttc ccgtcaactg gatcggtcga
    10621 aaaggaaaac caaacgttgt tgataaagat gaagcgattc gccgtgacac aagtctggat
    10681 cagctcgcga aacttgctcc gatttatgca agtgacggtt ctatcacagc cggcaatgct
    10741 cctggagtca atgacggagc cggcgcgttc gtgctgatgt ctgaggaaaa agctgctgag
    10801 cttggcaaac ggcctctggc tacaattctt ggtttttcaa ctacgggaat gccagcgcac
    10861 gagctggcgg cagcgccggg gtttgccatt aacaagctcc tgaaaaagaa cggtttaact
    10921 gtccaagata ttgacttgtt tgaagtaaat gaagcttttg cttcagttgt tttgacatgt
    10981 gaaaaaatcg taggtttcga tcttgaaaaa gtaaatgtaa atggcggtgc gatcgcgctc
    11041 ggacacccga tcggcgcgag cggtgcgaga attctcatga cgcttgttta tgaattaaag
    11101 cgacgaggag ggggtctggg cgttgccgct atttgcagcg gggcagcaca gggagacgcc
    11161 gtcttagtgc aggttcatta aaacatgatg aaaaagggga tttgaatgga aatcaaacaa
    11221 atcatggtag ctggcgcagg tcagatggga agcggaattg ctcaaacagc tgccgacgca
    11281 ggcttttatg tgcggatgta tgatgtgaat ccagaggccg cggaggcagg attgaaacgg
    11341 ctgaagaaac agctggcccg tgatgctgag aaaggaaaaa ggaccgagac ggaagtgaag
    11401 agcgtaatca gccgcatttc gatttctcaa acgcttgagg aggcagagca tgcggacatt
    11461 gtgattgagg ctatcgcaga aaacatggcg gcaaaaactg agatgtttaa aacacttgat
    11521 cgcatttgcc cgcctcatac gattttggcc agcaatacat cttccttgcc tattacagaa
    11581 atcgctgctg taacaaaccg gcctcaacgg gttattggca tgcattttat gaatcccgtc
    11641 cctgtaatga agctggttga agtgattcgc ggcttggcta catcagaaga aacggcctta
    11701 gatgttatgg cattagcgga aaagatgggg aaaacagcgg tagaagtcaa tgattttcct
    11761 gggtttgttt ccaaccgtgt gcttcttcca atgattaatg aagccatcta ttgcgtgtat
    11821 gagggagtgg cgaagccgga ggcaatagac gaagtgatga agctgggcat gaatcatccg
    11881 atgggtccgc ttgcattagc ggattttatc ggactggata cgtgtttatc aattatggaa
    11941 gtccttcact caggccttgg cgattccaaa taccgtccat gcccgctgct ccgcaagtat
    12001 gtcaaagcag gctggcttgg caaaaagagc ggacgcggtt tttatgacta tgaggagagg
    12061 acttcctgaa gtctattcca tccgggggtg gccgagttgc atgtaaccca agagcaagtc
    12121 atgatgcgaa aaatggtgcg tgattttgca cgaaaagaaa ttgctcccgc tgcggaaatc
    12181 atggagaaaa cggacgaatt tccctttcag ctgatcaaaa aaatgggtga acacggcctg
    12241 atgggaatac cggtgccgga acagtacggc ggtgtcggtg cagacgttgt ttcttatatt
    12301 ttggcgattc atgagatttc tagaatcagc gcggctgtcg gcgtgattct ctccgttcat
    12361 acctcagtcg gcacgaatcc gattctgtat ttcggcaacg aagaacagaa gatgaaatat
    12421 ataccaaagc tcgcgtcagg agaccatttg ggcgcatttg cactaacgga gcctcactcg
    12481 gggtcggatg ccgggagcct ccgcacaaca gcaatcaaaa agaacggcaa atatctatta
    12541 aacggatcga aaatattcat aacgaatggc ggagcagctg atatctatat cacatttgct
    12601 ttaacagctc cagatcaagg caggcacggg atttcggctt ttattgttga aaaaaacaca
    12661 cccggtttta ccgttggaaa aaaagaaaga aagctggggc tttatggctc caatactacg
    12721 gaactgattt ttgataatgc agaagtgcct gaagccaatt tgcttggcaa agagggggat
    12781 ggctttcaca ttgccatggc gaatttaaat gtcggccgga tcggcattgc ggcacaggcc
    12841 ctcggaattg cagaggcggc tcttgatcat gccattgatt atgcgaagca gcgagtgcaa
    12901 tttggaaggc cgattgcagc caatcaaggc atatcattta agctggctga catggcgact
    12961 agggcagagg cggcaagaca tcttgtctac cacgctgcag accttcataa ccgcggccta
    13021 aactgtggaa aagaagcgtc tatggctaaa caatttgctt ccgatgcagc cgtaaaggcg
    13081 gcgttagacg ccgtccaaat ttatggggga tatggctata tgaaggatta tccagttgag
    13141 cgcctgcttc gcgatgcaaa ggtgacgcaa atttatgaag ggacgaacga gattcaaaga
    13201 ctgattattt ccaagtattt gcttggcgga acctgataga caaaaaacgc aaaaacggag
    13261 gttgaggata tggaggagaa acagcattat tctccagggt tggacggtgt gattgcggca
    13321 gaaactcata tttcttatct tgacacgcag tccagccaga ttttgataag aggctatgat
    13381 ttaatagaac tttctgaaac aaaaagctat ctggagcttg tccatttatt gctggagggc
    13441 aggctgccag aagaaagtga aatggaaacg ctggaacgta aaataaacag tgcctcaagc
    13501 ctgcctgctg atcatctccg tctgcttgag ctgctccctg aggacactca tccaatggat
    13561 agtctgcgta ccggcctgtc ggcacttgct ggctatgatc ggcaaattga tgatcggtct
    13621 ccttccgcaa acaaagaacg cgcctatcag cttcttggga aaatgcctgc cctcactgct
    13681 gccagctaca ggatcattaa taagaaagaa ccgattcttc cgcttcaaac cctatcctac
    13741 agtgcgaatt ttctctacat gatgacaggg aaattgccgt cttcattgga agaacagatt
    13801 tttgaccggt cgctcgtcct gtacagtgag catgagatgc cgaattcaac ctttgcggcc
    13861 agggtcattg catctacaca ttcagatctt tatggggctt tgactggggc tgtcgcttcc
    13921 ctgaaaggga atcttcacgg aggagcaaac gaagctgtga tgtatttgct tttggaggca
    13981 aaaacgacat ctgattttga gcagcttttg caaacaaaac tgaaaagaaa agaaaaaatc
    14041 atgggcttcg gccaccgggt gtatatgaaa aaaatggacc cgagagcact catgatgaaa
    14101 gaggcgctgc agcaattatg cgataaagcc ggtgaccatc gtttatatga gatgtgcgaa
    14161 gcgggtgagc ggctgatgga gaaggaaaaa gggctttacc cgaatttgga ttactatgct
    14221 gccccagtgt attggatgct cggcataccg attcctttat atacgccgat ctttttcagc
    14281 gcgagaacgt ccggtttatg cgcccatgtg atcgaacagc atgccaataa tcggctcttc
    14341 cgtccccgtg tcagttacat gggcccgcga tatcaaacaa aaccatgaaa ggaactggta
    14401 gaatgccgaa aacggatcgt gttatcgaag aaatcacaga ctatgtgctt gagaaagaga
    14461 ttactagtgc cgaagcgtat acaacagcgg ggcatgtatt gctggatacc ctgggctgcg
    14521 ggatcttggc gctacggtat ccggaatgca caaagctgct tggcccgatt gttccaggaa
    14581 cgactgtgcc gaatggaagc aaagtgccgg gaacgtcata tgttctcgat cctgtgaggg
    14641 cagcgtttaa tatcggctgc atgattcgct ggctcgatta caacgatacg tggctggcgg
    14701 cggagtgggg gcatccatcc gataacttgg gaggaatcct tgccgctgct gattatgtat
    14761 caagagtgag gctgtctgaa ggaaaagagc cgttaacagt acgcgacgta cttgagatga
    14821 tgatcaaagc acacgagatc caaggtgtgc tggcgttaga aaacagctta aatcgagttg
    14881 gccttgacca tgtgctgttt gtcaaagttg cgacaaccgc tgttgcggca aagcttttgg
    14941 gcggcggaag agaagaaatc aaaaatgcgc tttcgaatgc atggattgac aatgcagcat
    15001 tgaggacata ccgccattca ccaaatacag gctcgcgtaa atcatgggcg gcaggagatg
    15061 caacgagcag aggtgttcat ttggcgctga tgtcgttaaa aggggaaatg ggttatccga
    15121 cagccttgag tgcaccgggt tgggggttcc aagacgtttt attcaataag aaagagatca
    15181 agcttgcccg tccgctcgac gcttatgtca tggaaaatgt gttatttaaa gtgtcttatc
    15241 ctgcggaatt tcacgcccag acagcggcgg agtgcgccgt cattcttcac ccgcaggtaa
    15301 agaaccggat tgatgagatt gaccgagttg tcatcagaac gcatgaatcc gctatccgaa
    15361 tcattgataa aaaaggcccg ctccacaatc cggcagaccg tgatcactgc ctccaataca
    15421 ttacagcaat tggtttgctt tttggtgata tcacggcaca gcattatgaa gctgaaacag
    15481 cgagtgattc gagaatagat aaacttcgtg ataaaatgga agtgactgaa aataaaacat
    15541 ataccgagga ttatttgaaa cctgataaac gttccatctc aaatgccgtt caggttcatt
    15601 ttaaagacgg aacgagcacg gaaatggtgg aatgtgagtt tcccctcggc catcgttttc
    15661 gaagagagga agcagtgccg aaactgctgg aaaagttttc tgacaatctc aaaacccatt
    15721 ttcctgataa acagcacaaa cacatttatg agcgctgtac cagctatgag acattacaaa
    15781 cgatgcgcgt aaatgaattc gtagacatgt tctgcatgta aaagggggat ttgtttcatg
    15841 tcgtggatcg tcaataagca atcgtcacaa gaggagcttg ccgggcgttt ccgcaagctg
    15901 atgtcagcac cggacattct tcaaattccc ggcgcccatg acgggatggc cgctttgctt
    15961 gcgaaagaag ccggtttttc tgctatttat ttgtccggtg ctgcctatac agccagcagg
    16021 gggctgcctg atttagggat catcacatcg gcagagatag ctgaacgggc caaagatctt
    16081 gtacgtgcag ctgatctgcc tctgcttgtg gatatcgata cgggatttgg cggtgtctta
    16141 aatgccgccc gaacagcccg ggagatgctt gaagcaaggg tagcagccgt tcaaatagaa
    16201 gaccagcagc ttccaaaaaa atgcggacat ttaaatggca aacagctagt tccgataaag
    16261 gaaatggcgc aaaaaataaa agccattaaa caagcggcac cctcccttat tgttgttgcc
    16321 cgtactgatg ccagggcgca ggaagggctt gctgccgcaa taaaacgttc agaggcttac
    16381 attgaggcgg gagcggacgc aattttcccg gaagcgctac aggcggagaa tgaattccgc
    16441 cagtttgctg agcgtatccc cgttccgctc cttgcgaata tgactgaatt tgggaaaacg
    16501 ccatattatc gtgccgatga attcgaagat atggggtttc acatggtgat atatcctgtc
    16561 acctcgcttc gagcggcggc aaaagcttgt gagcggatgt ttggtttgat gaaggagcac
    16621 ggctcacaaa aagaaggact tcatgatatg cagacacgaa aagaactgta cgatacgatt
    16681 tcttattatg actatgaagc gttagacaaa acgattgcca agaccgtttt gcctgacgaa
    16741 taatgcaaca aaaaaagccg gagcattctc cggctttttt tcagctatcg ttttctgaat
    16801 cgcgggctga cttgattgcg ttttctgtct ctgtataaaa tgaacccggc cagcacatag
    16861 aggccgatcg caaaaaagat gaatcctgac aacccttgga gccaaagagc tgaaaatggc
    16921 ttgattgtat ggccgaaaag tgtatctctc atcagtttaa tgcctaaagc agaaatagcc
    16981 ccggggatga ctaatattaa aagcgcaaga agtcggctca tcttcagaaa acccctttat
    17041 cttttcattt cctttattgt ccagcggaaa aaatattttg tcaagagaag aaaacgtggt
    17101 aacatagggt tgtgcaaatt attgcaacgg aataaatagg tgtgcaaatt ttttcataca
    17161 aaggggtatc gggatgcaaa aggtactgat agtaggtgcc ggcaaaaggg gaacggcgtt
    17221 attacatatt ctgattaaaa cagccatcat agatatcatt gccgtagttg acaaagaccc
    17281 cgaggcgccg ggattgaaag aagcagaaca gtatgggatt gccgtttcat ctgattggaa
    17341 accttacata caacaaaaac cggatatcgt cattcatact accggcgatc aagccgtgtt
    17401 tgacaagctc cttcaaagaa agcatgaaga taccattgtc atgccgggaa aaatggcata
    17461 catcgttttt cagctgatgg aagaaaagca gcacctgatt caaatgctaa aagagcaaac
    17521 ctataaatat gacagaattt ttaattccac ccatgatgga atgattttta ttgatatcaa
    17581 tgaagaaatc attctcttta accatatggc cgaaaaaatg gtcgggaaaa aacgtgagga
    17641 agtcattggg cgcccaataa aagaagtgat tccgagcacg aagatgccgc ggattttaaa
    17701 aacaagagtg cctgaataca accagaagca actgttaggc gatcatttgc aaattgtgac
    17761 cacaagactg ccgattattg atgaaggcgg acgtctgctc ggggctcttt gtgtgtttaa
    17821 agatatcact gatgcggtcg agctggcaga ggaagtgacc aacttaaagc aggtccgtac
    17881 gatgctggag gcgattattc aatcctccga tgaggcgatt tctgtcgttg atgaaaacgg
    17941 catcggcctg ctaatcaata aagcgtatac gaaaatgacg gggctttctg aaaaagaagt
    18001 catcggcaag cctgcaaaca ctgatatttc cgaaggcgaa agcatgcatt taaaggtgct
    18061 tgaaacaaga cgtcctgtcc gcggtgtcag aatgaaggtc ggcccgaatg aaaaagaggt
    18121 catcgttaat gtagcaccgg tgattgtgga cgggattttg aaaggcagcg tcggcgtgat
    18181 tcacgatgtt tccgaaatta aaatgctgac agcggagctt aaccgcgcca gacaaattat
    18241 tcgcacgctt gaagcgaaat acacgtttga cgacattatc ggcaaaagcg agcaaatgct
    18301 ggttgcgctt gagcaggcga agctcggtgc gaaaacaccg gcaaccatct tgctgcgcgg
    18361 ggaatcagga acaggaaaag aactgttcgc ccatgccatc cataacgaaa gtgaccggaa
    18421 atacaataaa tttattcgcg tgaattgtgc agccctttct gaaaacctgc tcgaatcaga
    18481 attgttcggc tatgaggatg gtgcgttttc aggagcgaag cgcggcggta aaaagggttt
    18541 atttgaggaa gcaaataacg gcagtatttt cttagatgaa atcggtgagc tgacacaaaa
    18601 tatgcaggcc aaattgctgc gcgtccttca agaaaaggaa atcgtcagag tgggcggcac
    18661 gaaagcgatc cctgtcaacg tcagagtgat cgcggcgaca aatgtaaata ttgaaaaggc
    18721 gatggcggac ggaacattcc gggaagacct gtattaccgg atcaatcgct atccgatctc
    18781 catcccgcct ttgcggcagc ggttggagga cattgaagca ttgagcgtca gacttatcca
    18841 aaagatcaac cgggattacg gcaggaatgt aaaagggctc tcacagcaag ccttgcgcgc
    18901 cttatctgcc taccattggc ctgggaatgt ccgggagctt gaaaatgtcc ttggacgagc
    18961 catgattttt ctgaatccgc atatggaatg gattgaaaaa gatcacttgc ctgtattcga
    19021 acttgagcaa aaagaaaatg acacagacca gggaacaggt tttgattttc cggatattga
    19081 aggcgaaaag ctgtctgtcg cagtagaaaa atttgaagca catttgatcc agcaaacgct
    19141 tgaaaagcat cattttaacc ggacaaaaac agcaaaagct ctcggtgtca gcattcggaa
    19201 cttatattac aaaatggata aatatggcct tgcaaatgaa ggcatgcaat aatttgcaga
    19261 ataaacgcaa acatctgcac gaatgtttca atatacctgg tatgatagca cccttaagag
    19321 ctggcatgga acttgcataa taaaaggcgg agtcgaaaca agaaaggtgg taacagatga
    19381 agctgaaaga tttaatcggc aaagcgtcga tacacaaaaa taagaccatt gcggttgctc
    19441 atgctgagga tgaggaagtg atccgggctg taaagctagc agccgagcac ctatccgccc
    19501 gtttcttgtt aacgggcgac agcacaaaac tgaacgagct gacatcatcc atgcaagggc
    19561 atcaagtgga aatcgtccat gccgatactc ctgaggaatc ggcgaattta gcggttcgtg
    19621 ctgtgcatca taaaacagcg gacgttttaa tgaaaggcaa tgtgccgact tctgttttgc
    19681 ttaaagcggt attgaacaga caggaggggc ttcggtcagc aagtgtcctt tcccacgtgg
    19741 ctgtcttcga tataccggat tttgaccggc tgatgtttgt gacagattcg gcaatgaata
    19801 ttgctccttc gctggaagag ctccggcaga ttttgcaaaa tgctgttcat gtggcccatg
    19861 cagtggggaa caatatgcca aaagcagctg ctcttgcagc ggtcgaaacg gtgaacctaa
    19921 aaatggaagc aaccgtgaat gcagctgctc tagctcaaat gtacaaaagg ggccagatca
    19981 aaggctgcat tgttgatgga ccgcttgctt tggataacgc agtttcacaa attgccgcgg
    20041 ctcagaaaaa aatttcggga gacgtagcgg gcaacgcaga tatccttctc gtcccaacaa
    20101 ttgaggccgg caatatttta tataaatcac tgatttattt tgccaaggcc agcgtggcgg
    20161 ctgtcattac aggagcaaaa gcaccgattg ccttaacaag cagagcggac tctgctgaaa
    20221 ataaactgta ttccattgcg ctggcaatat gcgcatctga agaatacaca cattaggagg
    20281 aacgaacatg gaacttttta aatatatgga gaaatacgat tacgaacaat tggtattctg
    20341 ccaggatgaa caatctggat taaaagcgat tatcgccatt catgatacaa cgcttggtcc
    20401 ggcgcttggc ggaacgagaa tgtggacata tgaaaatgaa gaagcggcaa ttgaagatgc
    20461 gctcagattg gctagaggca tgacctataa gaacgcggcg gcaggcttaa accttggcgg
    20521 cggaaaaaca gtcattatcg gcgatccgcg caaagacaaa aatgaagaaa tgttccgcgc
    20581 gtttggccgc tatattcaag ggctgaacgg cagatacatc acggctgaag atgtgggcac
    20641 aacggtcgag gatatggata tcattcatga tgaaacagac tacgttacag ggatttctcc
    20701 tgctttcggt tcttctggaa atccgtcccc agtcacagcg tacggggtgt acagaggaat
    20761 gaaggcagca gctaaagctg ctttcggaac cgactctctt gaaggaaaaa ccattgctgt
    20821 acagggtgtt gggaacgtag cctataacct ttgccgccac ctgcatgaag aaggagcaaa
    20881 cttaatcgtt acggatatca acaaacaatc tgtacagcgt gcagttgaag attttggcgc
    20941 ccgtgcggta gaccctgatg atatttattc acaagactgc gatatttatg cgccgtgtgc
    21001 ccttggtgcg actattaacg acgacaccat taaacagctg aaggcgaaag tgatcgcagg
    21061 tgcggctaac aaccaattaa aagagacacg ccatggtgat caaattcacg aaatgggcat
    21121 cgtttatgca ccggattacg tgattaacgc gggcggtgtc atcaacgtgg cagatgagct
    21181 ttacggctat aatgcagaac gtgcattgaa aaaagttgaa ggcatttacg gcaatatcga
    21241 gcgtgtactt gagatttctc aacgtgacgg cattcctgca tatttagcgg ctgaccgctt
    21301 agcagaggaa cggattgaac gcatgcgccg ctcaagaagc cagtttttgc aaaacggcca
    21361 cagtgtatta agcagacgtt aagaaattga tctggaggtt atgaaagtgc tacatgacga
    21421 aaaacgcatt ctcacaatta atccaggctc aacttcaacg aaaatcggtg tttttcataa
    21481 cgaaagaagc atttttgaaa aaacattgag acacaacata gaagagctgc agcgatttga
    21541 ccgaattatt gatcagtatg aatttcgtaa aaaccatatt ctcgaaacgc ttcatgaaca
    21601 gggaatcaat atttcaaagt ttgatgcagt ctgcgcaaga ggcggccttc tccggccaat
    21661 tgaaggcggg acctacgtgg tgaatgatga catgattgag gatttgaaaa gcggctacgc
    21721 cggtcagcat gcttctaatc tcggcggcat tatcgcgcgg gaaatcgctg atggcctgaa
    21781 tatcccttcg tatatcgtcg accctgttgt cgtagacgaa atgtcagtgc ttgcgaaagt
    21841 gtcaggcatg cctgaaattg aacgaaaaag catttttcac gcattaaatc aaaaagctgt
    21901 cgctcgtaaa gcggcagcct cccttggcaa acgatatgag aacatgaaaa tgattattac
    21961 ccatatgggc ggaggtatta caattggcgt ccatgaccgc gggcgagtgg tagatgtcaa
    22021 taacggcctg cacggcgagg ggccattcag tcctgaacga gcaggaacag tgcctgcggg
    22081 agatcttgtt gatctatgtt tttcagggga atatacaaaa gaagaaatca tgaaaaagct
    22141 tgtgggcacc ggcggacttt taggctatct cggtacaaat gatgcagtaa aagtggaaca
    22201 gatgattcag gggggcgatg aaaaagcccg cttcatttat gatgccatgg catatcaggt
    22261 agcaaaggaa atcggggcag ccagcgcggc gttaaaaggc gaagttgaag cgattgtgct
    22321 gacgggaggc cttgcgtacg gcaaaagctt tgtttctgct atcagatcat acatagattg
    22381 gatttcagac gttttagtct atccgggtga aaatgaactg cagtctcttg cccaaggggc
    22441 gctcagagta ttgcagggcg aagagcaatc caaacaatat cgtattgaat agacagacag
    22501 gagtgagtca ccatggcaac tgagtatgac gtagtcattc tgggcggcgg taccggcggt
    22561 tatgttgcgg ccatcagagc cgctcagctc ggcttaaaaa cagccgttgt ggaaaaggaa
    22621 aaactcggag gaacatgtct gcataaaggc tgtatcccga gtaaagcgct gcttagaagc
    22681 gcagaggtat accggacagc tcgtgaagcc gatcaattcg gggtggaaac ggctggcgtg
    22741 tccctcaact ttgaaaaagt gcagcagcgt aagcaagccg ttgttgataa gcttgcagcg
    22801 ggtgtaaatc atttaatgaa aaaaggaaaa attgacgtgt acaccggata tggacgtatc
    22861 cttggaccgt caatcttctc tccgctgccg ggaacaattt cggttgagcg gggaaatggc
    22921 gaagaaaatg acatgctgat cccgaaacaa gtgatcattg caacaggatc aagaccgaga
    22981 atgcttccgg gccttgaagc ggacggtaag tctgtactga cttcagatga ggcgctccaa
    23041 atggaggagc tgccacaatc aatcatcatt gtcggcggag gggttatcgg tatcgaatgg
    23101 gcgtctatgc ttcatgattt tggtgtgaag gtaacggtta ttgaatacgc ggatcgcata
    23161 ttgccgactg aagatctaga gatttcaaaa gaaatggaaa gtcttcttaa gaaaaaaggc
    23221 atccagttca taacag
//
