LOCUS       gnlProkkaFGGCBLHG_41    1849 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FGGCBLHG_41.
ACCESSION   gnlProkkaFGGCBLHG_41
VERSION     gnlProkkaFGGCBLHG_41
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 05:05:56
            Original ID  :: gnl|Prokka|FGGCBLHG_41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1849
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1849
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:1849]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..1849
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..1849
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1849
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             2..1849
                     /NRPS_PKS="Domain: AMP-binding (13-401). E-value: 4.7e-106.
                     Score: 346.6. Matches aSDomain:
                     nrpspksdomains_ctg37_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (506-574). E-value: 2.7e-28. Score:
                     89.9. Matches aSDomain: nrpspksdomains_ctg37_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     352.1; E-value: 7.1e-107)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-115, bitscore:
                     372.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1e-20, bitscore:
                     60.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.9e-09, bitscore:
                     21.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPVPTDKTVHQLFEETVQRHKDRPAVTYNGQSWTYGELNAKANR
                     LARILMDCGISPDDRVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDS
                     GAKLLLKQEGISVPDSYTGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTS
                     GTTGQPKGVMVEHHALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAE
                     LHVIDEAIRLDIVRLNNYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAV
                     KKPYTLVNNYGPTENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGE
                     LCVAGRGLARGYLNREDETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVK
                     VRGYRIELSEIEVQLAQLSEVQDAAVTAVKDKGGNTAIAAYVTPETADIEALKSALKET
                     LPDYMIPAFWVTLDELPVTANGKVDRKALPEPDIEAGSGEYKAPTTDMEELLAGIWQDV
                     LGIPEVGVTDNFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHPTIEELTQYVERAEG
                     KQADQGPVEGEVILTPIQRWFFEKNFTNKHHWNQSVMLHA"
     aSDomain        41..1204
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg37_1_AMP-binding.1"
                     /evalue="4.70E-106"
                     /label="ctg37_1_AMP-binding.1"
                     /locus_tag="ctg37_1"
                     /protein_end="401"
                     /protein_start="13"
                     /score="346.6"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEETVQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPD
                     DRVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISV
                     PDSYTGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTGQPKGVMVEH
                     HALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIV
                     RLNNYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPT
                     ENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYL
                     NREDETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVR"
     aSModule        41..1723
                     /complete
                     /domains="nrpspksdomains_ctg37_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg37_1_PCP.1"
                     /locus_tags="ctg37_1"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       227..268
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg37_1_0001"
                     /evalue="5.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg37_1"
                     /protein_end="89"
                     /protein_start="75"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LGVLKAGAAFVPID"
     CDS_motif       470..529
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg37_1_0002"
                     /evalue="4.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg37_1"
                     /protein_end="176"
                     /protein_start="156"
                     /score="34.6"
                     /tool="antismash"
                     /translation="AYMIYTSGTTGQPKGVMVEH"
     CDS_motif       869..898
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg37_1_0003"
                     /evalue="3.20E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg37_1"
                     /protein_end="299"
                     /protein_start="289"
                     /score="10.1"
                     /tool="antismash"
                     /translation="NYGPTENTVV"
     CDS_motif       1001..1090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg37_1_0004"
                     /evalue="2.30E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg37_1"
                     /protein_end="363"
                     /protein_start="333"
                     /score="51.8"
                     /tool="antismash"
                     /translation="PEGVAGELCVAGRGLARGYLNREDETAKRF"
     CDS_motif       1169..1234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg37_1_0005"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg37_1"
                     /protein_end="411"
                     /protein_start="389"
                     /score="36.5"
                     /tool="antismash"
                     /translation="YIGRIDQQVKVRGYRIELSEIE"
     aSDomain        1520..1723
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg37_1_PCP.1"
                     /evalue="2.70E-28"
                     /label="ctg37_1_PCP.1"
                     /locus_tag="ctg37_1"
                     /protein_end="574"
                     /protein_start="506"
                     /score="89.9"
                     /tool="antismash"
                     /translation="EELLAGIWQDVLGIPEVGVTDNFFSLGGDSIKGIQMASRLNQHGW
                     KLEMKDLFQHPTIEELTQYVERA"
     CDS_motif       1769..1798
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg37_1_0006"
                     /evalue="3.80E-05"
                     /label="NRPS-E1"
                     /locus_tag="ctg37_1"
                     /protein_end="599"
                     /protein_start="589"
                     /score="16.3"
                     /tool="antismash"
                     /translation="LTPIQRWFFE"
ORIGIN
        1 ggcgctgcct gtgccgacag acaaaacagt tcatcagcta ttcgaagaga ctgtccagcg
       61 ccacaaagac cgcccggctg tcacatacaa cggccagtct tggacgtacg gcgagctgaa
      121 tgcgaaggca aaccgtcttg cacggatttt gatggactgc ggcatcagcc cggatgaccg
      181 cgtcggcgtt ctcacgaagc cgtcgcttga aatgtccgcc gcggtgctcg gcgtcttgaa
      241 agccggagcg gcgtttgtgc cgattgatcc tgactacccg gatcagcgga ttgagtatat
      301 tttacaggac agcggcgcga agctcctctt gaaacaggaa ggcatttcag tgccggacag
      361 ctatacggga gatgtcattc ttctcgacgg aagccgcacg attctaagcc tgccgcttga
      421 tgaaaacgac gagggaaatc cagagacggc tgtaaccgcg gagaacttgg cgtacatgat
      481 ttacacgtct ggaacgaccg gacagccgaa gggtgtcatg gtcgagcacc atgcgcttgt
      541 gaacctgtgc ttctggcacc acgacgcgtt cagcatgaca gcggaggacc gcagtgcgaa
      601 gtacgcgggc tttggattcg acgcttccat ttgggagatg ttcccgactt ggacgatcgg
      661 cgctgagctt cacgtcattg atgaagcgat ccgcctcgat atcgtccgcc tgaacaatta
      721 cttcgaaacg aacggcgtaa cgatcacgtt cctgccgaca cagcttgcgg aacagttcat
      781 ggagcttgag aacacatcac ttcgcgtcct cttgaccgga ggagacaagc tgaagcgcgc
      841 agtgaaaaag ccgtacacac tcgtcaacaa ctacggaccg acagaaaaca cggtcgttgc
      901 cacaagcgca gaaatccatc cggaggaagg ctcgctttcc atcggaaggg ccattgccaa
      961 tacgagagta tacattctcg gcgagggcaa tcaggtgcag ccggaaggcg tagccggaga
     1021 gctttgcgtg gcggggcgcg gactggcacg aggctatctg aatcgagaag acgaaaccgc
     1081 gaagcggttt gtcgctgatc cgtttgtgcc gggtgagcgc atgtaccgca ccggcgattt
     1141 ggtgaaatgg acgggcggcg gcatcgaata catcggccgg atcgaccagc aggtcaaggt
     1201 ccgcggctac cggatcgagc tttcagaaat tgaagtccag ctcgcccagc tttctgaggt
     1261 gcaggatgcg gcggtgacag ctgtcaagga taaaggcggc aatacagcaa tcgcggcgta
     1321 tgtcacaccg gaaacagctg acatagaagc actgaaatca gcactgaagg aaaccctgcc
     1381 ggattacatg atcccggcgt tctgggtgac gctggacgag cttccggtta cggcaaacgg
     1441 caaggtggac cgcaaagcgt tgcctgagcc ggacatcgaa gcgggaagcg gagaatacaa
     1501 agcgccgacg actgacatgg aagagctgct tgccggcatc tggcaggacg tgcttggaat
     1561 acctgaagtc ggtgtcaccg acaatttctt ctcgcttggc ggagattcca tcaaaggaat
     1621 tcaaatggcg agccgcttga atcagcacgg ctggaagctg gaaatgaaag atctcttcca
     1681 gcatccgacg atcgaagagc ttacccaata tgtagagcgt gccgaaggca aacaggcaga
     1741 ccaaggcccg gtagagggcg aagtcatcct gacgccgatc cagcgctggt tctttgaaaa
     1801 gaacttcacg aacaagcacc actggaacca atcggtgatg cttcacgcc
//
