LOCUS       c00040_gnlPro..        14725 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PCAHCHCD_42.
ACCESSION   c00040_gnlPro..
VERSION     c00040_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 05:47:35
            Original ID  :: gnl|Prokka|PCAHCHCD_42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 62285
            Orig. end    :: 77010
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14725
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[72285:73113](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..10828
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14725
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14725
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             832..1341
                     /locus_tag="ctg40_63"
                     /transl_table=11
                     /translation="VLHDHLNVLTLFALSGEIVGRKKLQKMVYIAKQMGYPFNERYHFH
                     RYGPYSDELTVRLEELCNLGFLIESEEDKGHYSQYRYTLSPQGQAFLEMYHPPVAGYKD
                     LCQALNNQSARFLELLSTILYFSDLEEGARREKIRQLKKKQNYSDDDFDEAHTYLQKLA
                     QLVASA"
     CDS             1447..1650
                     /locus_tag="ctg40_64"
                     /transl_table=11
                     /translation="VEPLVLSFVLMLLLFAAGIPLLLILILHYPLIGACVIAFISINWF
                     IAARLHRKHERMQHAGHDKNGL"
     CDS             complement(1802..1996)
                     /locus_tag="ctg40_65"
                     /transl_table=11
                     /translation="MPIVTVQLLEGRTDEQKRALVEKVTDAVSETTGAPKERVSIIISE
                     MKPNDYGVAGKRPSDQNEQ"
     CDS             complement(2058..2741)
                     /locus_tag="ctg40_66"
                     /transl_table=11
                     /translation="VALRKSNGKQGRFKKTALLFVAAAFIAFGLWLTTTTGFKLAYGYF
                     LYKIGAHSETETVAAPVEEAPEAIPAYENDRQDVASWQPEIGEQMGTLTIPKIDATLPI
                     IHGTNEDELDKGVGHFADSVLPGEKDNSVLSGHRDTVFRKLGEVGEGDELIVETRSGVY
                     TYKVHTVRIVDEDDRTVIVPTEEAQLTVITCYPFDFIGAAPDRYVLVADLIDQDVYETL
                     ALFPK"
     CDS             complement(2744..3877)
                     /locus_tag="ctg40_67"
                     /transl_table=11
                     /translation="MKKSLFTAIFTLLFLFSAPAASLAHGFDNEEFTAYLEDVGVSEKD
                     LAEHLMYWWEGTTFYDFTDVSELAEFLGPRLTEEGINEIAAEFDLTRQELDELLEEWLG
                     LPPSDLLFYNTFYMVVHVIITLEDEWGNEPYYPDFSGFLSEFSLSDEEEWALYEHFWYI
                     QETNPNLSAELDDLKQRAYAFDGFESIRELSAADVAELFAIGEKAISVLDLHPKYYLDR
                     VGEDPKPISYKELMSGNAIKGYDLLVELYDADGSFLADFYITAEMFNSHFVKKIVDDVT
                     QIDKGLKDKPKKPSLESALPGKDEAPLPAKAGNDANHNDGGKKAERDENGKVTKTANGA
                     KMPKTATNYPLYMLIGIGMSLAGVLIFRRLLREKKVA"
     CDS             4152..4709
                     /locus_tag="ctg40_68"
                     /transl_table=11
                     /translation="VDLLNNDNLKKAKKKSSSFTILSNDSTDGHGGYGAGVINLDNVTP
                     LFIDIEEKEAFVDMGALHARSAVEKRVKFIADEEAVPKEGLKRYWLVWVTIDTKDKKPY
                     YSGVAACYMTVNKQAKRGYKSMPEHVNHMDKSLKGKLVVSQMDDSSRQVLKAFLKNHNE
                     EMWNHSSQELHDALESSENVNN"
     CDS             complement(4836..6623)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_69"
                     /sec_met_domain="Peptidase_M3 (E-value: 2.3e-71, bitscore:
                     233.6, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSTYKSRKDVPEHEKWDLTDLYADEQAWQADVDQCYQLADTLSQF
                     DGAIQDAKSLLDFLETQEKLSFTLRKVFAYTMFLSDIDTRDAHAQKLSAKATQLSVKVS
                     ESTSFFMPFLLSLSEETLRAYISAEKKLGYFEDELWKSFRFKKHVLTKEKEELLSQLGA
                     TFQAPGDTYNMLNNADIQFGTVTDDNGQQVQLTRGMYSKLIEDEDRNKRKEAYKAYYKP
                     YVELNNTIATTLSAEIKTNVTLAKVRQYESALHKALFADNIEQSVYDQLIDAAKANIAP
                     LHEYARLRKQKLGLDELRQYDLNAPIVPGVKAEISYEEAYETMLKALKPLGDDYIAKLK
                     EFKEKRYIDVRETPGKRSGAYNMGVYGVHPFVLLNHHDDLNSLFTLVHEMGHAMHSYYS
                     SKYQPQITANYRIFVAEVASTVNEVLLINYLLKETSDKKMRAYLLNHFIEQFRGTFFTQ
                     VMFADFEKQTHERAEAGEPLNAESLNELYEQLFRTYNGPDIVFDDEVKYGWSRIPHFYR
                     AFYVYQYATGFASAIKIATAILDGEEGALDAYMTFLQSGSSDEPLELLKKAGVDLTTPE
                     PVQAAMARFSALVEELKQL"
     CDS             6800..7618
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_70"
                     /sec_met_domain="Acetyltransf_1 (E-value: 2.2e-15,
                     bitscore: 49.3, seeds: 223, tool: rule-based-clusters)"
                     /sec_met_domain="Acetyltransf_10 (E-value: 2.2e-07,
                     bitscore: 23.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSEQKKAIQSLQEKVEQADGIKLKLNWDLLEGERSLNGTEDYF
                     YYNEKGELLGYLAVYFFGNKMECCGMVDPAARRRGIGRMLLDQAASDWQGKTKQFLLNS
                     PTDSESGIAFMKAVGAEYAFTEKQLVCREVPIPYTKKGIRIRPAVSNDEERIYELDAEG
                     FHMTKDEAKALHHNNPTWVTYMIEEDNHPVGKLSISRQDQESWIYAFVLTKEKRGQGIG
                     RAALTDIVHREVSNGKTVWLDVVCTNEAALTLYHTCGFTEVGSQTYYTLK"
     CDS             complement(7714..9840)
                     /locus_tag="ctg40_71"
                     /transl_table=11
                     /translation="MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGP
                     PPIDAVQTTQFLAADGTVMGKEEAGQNRFSLPLAEMSPYLLQATIAIEDRKFYSHYGFD
                     LKRIGGALLANLQSGSKAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMNFSK
                     DEILAGYLNTVYYGHGAYGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDL
                     EKAKSRQELILDSMVGEGMIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLH
                     NEAQMDEAAVDTGGLIIETTLDPALQQQAEDLVEKHMPDNGLQVALIAMDPRNGEVKAL
                     VGGTDYNESSYNRATQAMRNPGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGRED
                     YAPSNYNDIYANDFITMLEAIAYSDNIYAMKTHLSIGTDELVNVSEKLGLGTFENRPSL
                     ALGAQPVTVLDIANAYAALADGGKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAF
                     VLTDMLRGVFEPALNSYTSVTGASVAAQLTHPTAGKSGSTPRDSWMVGYTPQLVTAVWV
                     GFDKDKDINQSVEGQISKRIWADFMEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDA
                     CPNGRTTYFLAGTAPVNTCAEPEAAEDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSG
                     PTILDEGEESPATE"
     CDS             10001..10828
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_72"
                     /sec_met_domain="Spermine_synth (E-value: 3.2e-73,
                     bitscore: 237.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 9.3e-23,
                     bitscore: 72.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFWFTEKQTERFGITMKIKRTLHTEKTDFQQLDMVETEEFGNML
                     LLDGMVMTTEKDEFVYHEMVTHVPLFTHPNPKHVLVVGGGDGGAIREILKHPSVEKATL
                     VDIDGKVIEYSKTYLPTIACALEDERVDVKVADGFMHIAKSANEYDVIMVDSTEPVGPA
                     AKLFERGFYEGISKALKEDGIFVAQTDNPWFHQELVSNVYKDVKEIFPITRLYTANIPT
                     YPSGMWTFTIGSKKHDPLAVEATRFHDVQTKYYTPDIHRAAFVLPKFVQDLLK"
     CDS             10840..11718
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_73"
                     /sec_met_domain="Arginase (E-value: 4.1e-81, bitscore:
                     264.8, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIMSRASYEEADAVIYGMPMDWTVSFRPGSRFGP
                     ARIREASLGLEEYSPYADKHLEEVNYFDAGDIPLPFGNAARSLDIVEEYVDSLLADGKF
                     PLGLGGEHLLSWPIFKAMYRKYPDLAIIHIDAHADLREQYEGEALSHSTPIRKACELIG
                     AENVYSFGIRSGMREEFAYAKEAGMHLYKFDVAEPLKNVLPHLSGRPVYITIDIDVLDP
                     AHAPGTGTAEAGGITSKELLEAQMLLSQADIQIVGADLVEVAPAYDPTEQTAIAASKFV
                     REMLLGWVHKK"
     CDS             11834..12265
                     /locus_tag="ctg40_74"
                     /transl_table=11
                     /translation="MKRKVKISFQTTTFIKGQQPDAFSFDTEGDLYIKGSASYLRFKET
                     HAHKQDVFSTMKWDGRELMLIRQGTIIMRQSFLAKEETYGRYVTPEASWETKARTDTLL
                     VQLPTGAKQKGRIYVRYQFFLQGQLTGEHEIRLAMKQIE"
     CDS             12477..14147
                     /locus_tag="ctg40_75"
                     /transl_table=11
                     /translation="MNHMERKKEQLRMEVRRAVLQAELATESEVPSVLLEVPKDKAHGD
                     FATNIAMQLARIAKKAPRAIAEELVANFDREQAGIEKIEIAGPGFINFFLDNGYLRELI
                     PQVLDEKDDYGRSDVGQGEKVLIEFVSANPTGDLHLGHARGAAVGDTIANIMEKAGYKV
                     SREYYINDAGNQIENLAASLNARYLQALGEEKPMPEDGYHGQDIIDIAKQLVDEVGDQY
                     RQMDEKERLAFMREYGLKKELEKIKQDLNAYRVEFDKWFSETSLYESGQVKRGLQVLKD
                     KNETYEKDGATWLRSTAYGDDKDRVLVKQDGTYTYLTPDISYHLDKFDRGYDRLIDVLG
                     ADHHGYIPRMRAAIQALGYDPDRFNVQIIQMVSLFQGGEKVKMSKRTGKAVTLRELMEE
                     VGVDATRYFFAMRSPDTHLDFDMDLAVSKSNENPVYYIQYAHARVCSILRQGEELGIPY
                     SANTDLSPIASEKEYELLKAIGEFPGAVAEAATKQIPQRIANYAYDLAQALHSFYNVTR
                     VIDTENKDLSAARLALMKATQMTIKNALALLGVEAPEKM"
     CDS             14150..14626
                     /locus_tag="ctg40_76"
                     /transl_table=11
                     /translation="MDTLWWLVIAVFFIASFVGLIVPIIPSVLVLWGGFLVYVFALEGS
                     LSVVFWVGMAVLTVFLLVVDLLANMAFVKRTGGSKWGERAALVGVIVGAFVVPPFGLII
                     VPFVLVLIAELLQKQPFEKAVRIAFASFLAFISGTLAKAVVQIVMIAWFLIEVL"
ORIGIN
        1 gtgtctagta tgatctcaag ccaaatcgat gctgatcgga tggattattt gttgcgagac
       61 gcctattaca caggagtcag ctacggccag tttgacttgg agcgaatctt gcgtgtcatg
      121 cgaccaaaaa atgatgaagt cgtgattaaa gctagtggca tgcatgctgt tgaagattat
      181 attatgagcc gataccaaat gtattggcaa gtgtatttcc acccagtgac gcgaagctca
      241 gaagtcattc ttagcaaaat tttaatgcgc gtgaaagatt tgcaagaacg tggctatgac
      301 tttaagcaaa aaccacttca ttttttatcc ttgtttgcag gtgagattac gttagaggat
      361 tatttgcgtc ttgatgaatc gattgtccat tattattttc aaagttggca ggaagaagat
      421 gacgccatct tgaaagattt gtgcaatcgt tttttaaatc ggcgcttatt ccagtatatc
      481 gaatttcatc cgaacgagcg gatgaaagac tggccgaaac ttgaggcttt gtttgcggaa
      541 gctggggttg atccaagtta ttatcttgtc atggactctt cttctgattt gccttacgat
      601 gtgtatcgtc caggggagga agagcggttg ccgattcatt tattaatgcc agacggttca
      661 ctaaaagagt tatcgacaca ctcggatgtt gtcgaagcca tatccggaaa aaaacgaacc
      721 gatcataaac tttattaccc agcggacgta ttaacggata cacgtgtcga taaggacatc
      781 cgagacagca ttcaatcatt acttgcgact acataaagga ggaagactgc cgtgctgcat
      841 gaccatttaa atgttctgac gctgtttgcg ctgtcaggtg aaattgttgg cagaaagaaa
      901 ttgcaaaaga tggtctatat cgcaaaacag atgggctatc catttaatga gcgttaccac
      961 tttcatcggt acggccctta ttcggacgag ctgacagtgc gattagaaga gttgtgcaac
     1021 cttggttttt taatcgagag cgaagaagac aaaggccatt attcacaata tcgctatacg
     1081 ctttcgcccc aagggcaagc gtttttggaa atgtaccatc cccctgttgc cggctacaaa
     1141 gacttgtgcc aagcattgaa caaccaatca gctcgttttt tagagctatt gtctaccatc
     1201 ctttatttta gcgatttaga agaaggggca aggcgtgaga aaatacgtca gctcaaaaaa
     1261 aagcaaaatt atagcgatga tgattttgat gaagcccata catacttgca aaaactggcc
     1321 caacttgtag ccagtgctta aatagaatcg ctcatagatt ttacatgttg tttgacaagg
     1381 attttgtaga tatggcgccg gtttagcgct acactagaaa agtgaaagga attcaaggaa
     1441 agaagggtgg aaccactcgt gctcagcttt gttctcatgc tccttttatt tgcggctggg
     1501 attccgttgc ttctcatttt gatactccat tatccgttga tcggcgcttg tgtaatcgcc
     1561 tttatttcta taaattggtt cattgccgca cgcctccacc gtaaacacga gcggatgcag
     1621 catgcaggcc atgacaaaaa cggactgtaa tccgatgata cagcccgtcg gccatgcgtt
     1681 ttgattgcat ggcttttttc gtgattttta acaaagcgat ggccttctct caaaagtata
     1741 tgagactgct gtctttaatt ggagacggcc cgccttagat tgtaggaaaa ggcacccatt
     1801 cttactgttc gttttgatcg cttggccgtt ttccagcgac tccgtagtcg tttggtttca
     1861 tttcgctaat gatgatggaa acacgttctt ttggtgcgcc tgttgtttca ctaacggcat
     1921 ctgttacttt ttcaactaat gcgcgttttt gctcatctgt acggccttca agcagttgaa
     1981 cggttacaat tggcataaaa aagccccttt cttttcgaga atacattcag tataccaaaa
     2041 gaaaggggct gttttgatca tttaggaaaa agcgcgagtg tttcataaac gtcttgatcg
     2101 attaaatcag cgacaagcac ataacgatct ggggcagcgc caataaaatc gaatggataa
     2161 caagtgatca ccgtcagctg tgcttcttcc gtcggaacaa tgacggtgcg gtcatcttca
     2221 tcgacgatcc gtaccgtatg caccttatac gtgtagacgc cacttcgtgt ttcgacaatg
     2281 agttcatccc cttcgccaac ttctcctagt ttgcggaaca cggtatcacg gtgtccagat
     2341 aaaacggagt tgtccttttc tccaggaaga acactgtcgg caaagtggcc gacgccttta
     2401 tccaattcat cttcatttgt cccatgaata atcggaaggg tcgcgtcgat ttttgggatc
     2461 gttaatgtcc ccatttgttc gcctatttct ggctgccagc tggcaacgtc ctggcgatcg
     2521 ttctcgtagg ccggtatagc ttctggtgcc tcctcaactg gggcagcgac cgtttccgtt
     2581 tcgctgtgcg ccccgatttt atagagaaag taaccgtacg ccagcttaaa gcctgtcgtt
     2641 gttgtcaacc aaagtccgaa agcaataaag gcggcggcga cgaaaagcag agctgtcttt
     2701 ttgaaacggc cctgctttcc atttgattta cgaagagcca cttttaagcg accttcttct
     2761 cacggaggag gcggcggaag ataaggacac ctgcaaggga cattccgatg ccgatcagca
     2821 tataaagggg atagtttgtt gctgtttttg gcattttggc accatttgcc gtttttgtca
     2881 ctttgccgtt ctcatcacgt tccgcttttt tgccgccgtc gttatgattg gcgtcgtttc
     2941 cagcttttgc cggaagcgga gcttcgtctt tgccaggaag cgccgactcc aatgatggtt
     3001 tttttggttt atcttttagg cctttatcaa tttgagtgac gtcatcaacg atttttttga
     3061 caaaatgaga attgaacatc tccgcggtaa tataaaaatc ggccaagaat gatccatccg
     3121 catcgtatag ctcgaccaat aagtcgtacc ctttaatcgc gttgccgctc attagctctt
     3181 tatagctaat tggctttgga tcttcgccaa cgcggtcaag gtaatacttt ggatgaaggt
     3241 caaggacaga tattgctttt tcgccaatag cgaacagttc agcaacatcg gcagccgaca
     3301 gttcgcggat tgattcaaag ccgtcaaatg cgtacgcacg ttgtttcaag tcatcgagtt
     3361 cggcggataa gttcggattg gtttcctgaa tataccaaaa atgctcataa agcgcccact
     3421 cttcttcatc acttaaagaa aactctgaca aaaatcctga gaaatcaggg taatatggtt
     3481 cgttgcccca ttcatcttct aatgtgataa tgacatggac aaccatgtaa aacgtgttgt
     3541 aaaacaataa gtcgcttgga ggcaggccga gccattcttc aagaagctcg tccaactctt
     3601 ggcgagtaag gtcaaattca gcagcgatct cattaatgcc ttcttctgtt agccgtgggc
     3661 ctaaaaattc ggcaagctca cttacatcgg taaaatcata aaaagtcgtg ccttcccacc
     3721 aatacatcaa gtgttcagct aagtcttttt cgcttacgcc aacatcttct aaataagccg
     3781 taaactcctc attgtcaaat ccatgggcaa ggctggccgc tggagcggaa aaaagaaaga
     3841 gtagagtgaa aattgctgta aataacgact tcttcatttt gttcctccta tattcaattg
     3901 tcatttttat ccgtgcatat gaattatata aacatgatcg cttaatgtca cgacttattt
     3961 tcatatttta taaaaatttt ataatagagg ctgcttttgc caaaaaacga cgaaattcgc
     4021 ttgtctgtgt tgaagagggc aacggcgagg aggccgccac tttttctcaa aggcagagag
     4081 gatgaatggg cgtggcgttt tatgatacac tagtgtttag ctaaaatgaa atttgggagg
     4141 gccgataaaa cgtggatttg ctcaataatg ataacttaaa gaaagcgaag aaaaagtctt
     4201 ccagttttac gatattaagc aatgattcaa cagacggaca cggcggttat ggcgctgggg
     4261 tcatcaatct cgacaatgtg acgccgctat ttattgatat tgaagagaaa gaagcgtttg
     4321 tggatatggg tgccctccat gcccgctcgg cagttgagaa gcgtgtgaaa tttatcgctg
     4381 acgaagaggc ggtgccaaaa gaagggctca aacggtattg gcttgtgtgg gtcacaatcg
     4441 acacaaagga taaaaagcca tactatagtg gagttgcagc ctgttacatg acagtcaaca
     4501 agcaggcgaa acggggatac aagagcatgc cggaacatgt gaaccatatg gataaatcgt
     4561 taaaaggcaa attggttgtc agccaaatgg atgattcgtc acgccaagtg ctaaaggcgt
     4621 ttttgaaaaa ccataatgaa gaaatgtgga accattcttc gcaggaactc catgatgccc
     4681 ttgaatcaag cgaaaatgtg aacaactaat gaacaagttg ccgaaaatct tgtactcttt
     4741 tttcgcttcg gctacgctag agacatggat gaacatcctg acgataagta ctaggacaaa
     4801 aaagcagcgg aagggctctc cttccgctgc tttttttata gctgttttag ttcctccacg
     4861 agtgcagaga agcgcgccat cgcggcttgc actggctcag gcgtcgttaa gtcgacacct
     4921 gcttttttta gcagttcgag tggctcgtcg gaactgccgc tttgcaaaaa ggtcatataa
     4981 gcgtcgagtg cgccttcttc accgtctaaa atggctgtgg cgattttgat tgctgaagca
     5041 aagccagtcg catactggta aacgtaaaaa gccctgtaaa aatggggaat gcgcgaccag
     5101 ccgtatttga cttcgtcatc aaacacaatg tctgggccat tgtaggtacg gaacaactgt
     5161 tcataaagct catttaagct ctctgcatta agcggttcac ctgcttccgc tcgttcgtgc
     5221 gtttgctttt caaaatcagc aaacatcact tgtgtaaaaa aggttccgcg gaattgctca
     5281 ataaaatggt tcagtaaata ggcgcgcatt ttcttgtcgc ttgtttcttt cagcaaatag
     5341 ttaattagca acacttcatt caccgtggaa gcgacttcag cgacaaaaat tcgataattg
     5401 gccgtaattt gtggttggta tttgctggaa tagtagctgt gcatggcatg gcccatttca
     5461 tgaacgagtg taaacaagct gtttaagtca tcatggtggt tgagcaatac gaaaggatgg
     5521 acaccgtaga cgcccatatt gtaagcacca gaccgttttc ctggtgtttc gcgcacatca
     5581 atgtaacgct tttccttaaa ctcttttaat ttggcgatgt aatcgtcacc aagaggcttt
     5641 agcgctttca gcatcgtttc atacgcttct tcatatgaaa tttccgcttt cacaccagga
     5701 acaattggcg cattcaaatc atattgacgc aattcatcga ggccaagttt ttgtttgcgg
     5761 aggcgcgcat attcatggag cggtgcaata ttcgctttag ccgcatcaat caattggtca
     5821 tagacgcttt gctcaatgtt gtcggcaaat aaagctttat ggagagccga ttcgtattga
     5881 cgaactttcg ccaatgtgac atttgttttg atttctgctg acagcgtcgt tgcaatcgta
     5941 ttgtttaatt ccacgtacgg cttgtagtaa gctttgtatg cttctttccg cttgtttcga
     6001 tcttcgtctt cgatgagctt tgaatacatg ccccttgtca gttgcacttg ctggccattg
     6061 tcgtctgtca ccgtgccaaa ctgaatatca gcattgttca gcatattgta tgtgtcgcca
     6121 ggggcttgaa aagttgcgcc taattgcgac aaaagctctt ctttttcctt tgtcagcaca
     6181 tgttttttaa agcggaatga cttccacaat tcgtcctcga aatagccaag tttcttttcc
     6241 gcagaaatgt aagcacggag cgtctcttcg cttaaactta aaagaaacgg catgaagaag
     6301 gaggtggatt cactcacttt tacgcttagt tgtgtcgctt tggcacttaa tttttgggca
     6361 tgggcgtccc gtgtgtcaat atcggataaa aacatcgtgt aggcgaaaac ttttcgcaac
     6421 gtgaaggaga gcttctcttg tgtttctagg aaatcgagca agctttttgc gtcttgaatc
     6481 gcgccatcaa attgacttaa cgtgtccgct agctgatagc actggtctac atcggcctgc
     6541 cacgcttgtt cgtccgcata aaggtcggtt aagtcccatt tttcatgttc aggtacatct
     6601 ttacgggatt tgtatgtact caagaaaatc actccttgca tgttttttcg ttctagtgta
     6661 gcacttatcg ctgaaaatat gttcgtttct gcttttttgt atgaattttt gctggcggtg
     6721 gcaaaaatcg attcataaaa gttataaaaa taacggtcac gttctatgtt atactgagga
     6781 aaaaggcggt gacatgatca tgctctcgtc agagcaaaaa aaagcgattc aaagccttca
     6841 ggaaaaagtg gaacaagctg acggcattaa gcttaaatta aattgggacc tcttagaagg
     6901 tgagcgttcc ttaaacggca cggaagacta tttttattat aatgaaaaag gagagctgct
     6961 tggttattta gcagtttatt tctttggcaa taaaatggaa tgctgcggta tggtcgatcc
     7021 cgctgcaaga aggcgcggca taggtcgaat gcttcttgat caagccgcct ctgactggca
     7081 aggaaagacg aaacaatttc tgttgaatag cccgactgat tcagaaagcg gcatcgcgtt
     7141 tatgaaggca gttggagcgg agtacgcgtt tacggaaaag cagctcgtat gccgagaagt
     7201 tccgattcct tacacgaaaa aaggaattcg catccggccg gcagtatcaa acgatgaaga
     7261 gcggatttat gaacttgatg cagaagggtt ccatatgaca aaggacgaag cgaaggcgct
     7321 tcatcataat aaccctacat gggttacata tatgattgaa gaagacaacc acccagttgg
     7381 caagctcagc attagccgcc aagatcagga aagttggata tatgcttttg ttttaacaaa
     7441 agagaagcga ggacaaggca taggccgggc agctctgact gatattgtcc accgtgaagt
     7501 ctcgaatggc aaaacggtat ggctggatgt cgtttgcacg aacgaagcgg ctctaacgtt
     7561 gtatcataca tgcggtttta ctgaggttgg ttcccaaaca tactatacat taaaatagat
     7621 tggcgcaaat ggtcgtagct gcgagcgttt gtcgataacc tcactcagac tgatagaagc
     7681 tgagagctgc acaaacgtgc agctcctttt cgcttattca gtggcgggac tctcttcacc
     7741 ttcatcaaga atggttggcc cagagggatc actcgggtca ccgtcttcaa tgctaaacca
     7801 tttaaaaaaa cgtttgaaaa agcctggatc tttcgtttct ggctcttctt gtaagtcttc
     7861 ggctgcctct ggctcagcgc aagtatttac aggagcagtt cctgctaaaa agtaagtcgt
     7921 gcggccatta ggacaggcgt cgctcgttaa caacccagtg tgggggtcga tgtcaacggc
     7981 ttcaacccct ggcggttctt taaacggaag ctttagttca ttggccatcg ctgcttccat
     8041 aaagtccgcc caaatccgtt tcgagatttg cccttcaacc gattgattga tgtctttgtc
     8101 tttatcaaaa ccaacccaca cagcagtaac aagctgtggt gtatagccaa ccatccagct
     8161 gtcccgaggt gttgatccag attttccggc tgtcgggtgc gttagctgtg cggctacgct
     8221 tgcaccggta accgatgtgt agctgtttag cgccggttca aatacgccgc gcaacatatc
     8281 ggtcagcaca aaggctgtat cttcacggag gacttggcgg acaggcggtt tttgttcgta
     8341 gactttgttt ccctcgccgt cacgcacttg gcgtatgaat accggttccc gttgttttcc
     8401 tccgtcggct aaagccgcgt aagcattggc gatatcgagg acggtgacag gttgtgcccc
     8461 taaagcaagg gaagggcggt tttcaaatgt accaagtccc agtttttcag agacatttac
     8521 tagttcgtct gtgccaatag ataaatgcgt tttcatcgca taaatattgt ctgagtaagc
     8581 gatggcttca agcattgtaa taaaatcatt ggcgtaaatg tcgttgtagt tactcggagc
     8641 gtagtcttct cgaccatcat cataggaaaa ggatgtcgct tcacttaaaa acgtcgatac
     8701 gggcgtaaaa ccgttctcga gtgcagcgta atacaaaaat ggtttaatgg tcgacccagg
     8761 gttgcgcatg gcctgtgtag cgcggttata ggaactttca ttgtaatctg tgccgccgac
     8821 aagcgccttt acttccccat tgcgtgggtc catggcgatc agggcgactt gcagcccgtt
     8881 gtcgggcata tgcttttcga ccaaatcttc ggcctgttgc tgcaaggcgg gatcaagcgt
     8941 cgtctcaatg atcagtccac ctgtgtcaac ggccgcttcg tccatttgcg cttcattgtg
     9001 tagcagcgct ttaacatggt cttgaaaata aggcgcgatt tcttcttcct ctttatcagc
     9061 ttcgtccgca aaaaccagtt tttccgcttt tgctttgtct gcttctgcct cctcaatcat
     9121 gccttcccca accatgctat ccaaaatcag ctcttgcctg cttttcgctt tttcgagatc
     9181 attcaatggc gaatagtagc ttggtccttt cggaatgcct gcaagcattg ccgcttctgc
     9241 caatgacacg tcttttgccg atttcccaaa gaaatgctgt gcagctgctt caactccata
     9301 ggcgccatgc ccataataga cggtgtttaa gtaaccagct aaaatctcgt cttttgaaaa
     9361 attcatctcc agacggagtg cgtaaagcag ctcattccat tttcgcatat aggttttttc
     9421 gtggctcaaa taaaggttgc gtgcgtattg ttgtgtaatg gtgctcgccc cttgtgcttt
     9481 tgagccagat tgcaaattgg caaggagcgc tccgccgatt cgtttaaggt caaagccgta
     9541 atgggagtaa aactttcggt cttcaatcgc gattgttgct tgcaacaaat aaggtgacat
     9601 ttctgctagc gggagagaaa agcggttttg accggcttct tctttcccca taaccgttcc
     9661 gtctgccgcc aaaaactgtg ttgtttgcac ggcgtcaatt ggtggggggc cttgcatgcg
     9721 cgtataagat aataatagaa taatgcctaa cgcgatgacg ataagagaaa gcaacaaaag
     9781 ccgccaaata agcctgattt tgcgaaagcg tttccgcttt ttgcgcgtaa ctgtctgcat
     9841 gacttttcat cctttccccg gcaacttgtt tagtatacag tttgggaaaa aagcggtttt
     9901 tttaaacctt gttgtctttg caattcgtaa cgcatccgct atacttgctt tgggcgtaag
     9961 gaaaaatcat atgcctagcg agatatgaga ggtgacaagc atggagtttt ggtttacaga
    10021 aaaacaaaca gaacgatttg gcattacgat gaagataaaa cggacgcttc acacggagaa
    10081 gacagacttc caacagcttg atatggtgga aacggaagag tttggcaaca tgttgcttct
    10141 tgacggcatg gtaatgacga cagaaaagga cgaatttgta taccatgaaa tggtgacaca
    10201 tgtcccttta ttcacgcacc cgaacccaaa gcatgtcctt gtagtaggtg gcggcgatgg
    10261 cggggcgatc cgagaaattc ttaagcatcc ttctgttgaa aaagcgacgt tggtcgatat
    10321 tgatgggaag gtcattgaat actcgaaaac ctatttgccg acaattgcct gtgctttaga
    10381 agatgaacgt gttgacgtga aagtcgctga cgggtttatg catattgcca aatcagcaaa
    10441 tgagtatgac gtgattatgg tcgattcgac ggagcctgtc gggccagctg ctaaactgtt
    10501 tgagcgtgga ttttatgaag gaatttccaa agcgttaaaa gaagatggca tttttgttgc
    10561 gcaaacggat aacccatggt tccatcagga actagtgtct aatgtgtaca aagacgtaaa
    10621 agagatcttt ccgattaccc gtttgtacac cgccaatatt cccacttatc caagcggcat
    10681 gtggacgttt acgatcggtt ctaaaaaaca cgatcctctt gctgtagaag caacgcgttt
    10741 tcatgatgtc caaacgaaat attatacgcc agacatccat cgtgccgcat ttgtgctgcc
    10801 gaaattcgtc caggacttgc ttaaatagga ggcttttaca tgcgatttga cgaggcatac
    10861 tcaggcaagg tgtttattat gagccgcgcc agttatgaag aggcagatgc cgtcatttac
    10921 ggcatgccga tggactggac cgtttccttt cgtccaggtt cccgttttgg cccggcgcgg
    10981 atccgcgaag cttccttggg gcttgaagaa tacagccctt atgccgacaa gcacttggaa
    11041 gaagtcaact attttgatgc aggcgacatt cctttgccat ttggcaatgc agcccgaagc
    11101 ctagacattg tggaggaata cgttgattca ctcttagcag acggcaagtt cccgctaggc
    11161 ctgggcggcg aacatttgct gtcatggccg atttttaaag cgatgtaccg gaaatatccc
    11221 gacttagcga tcatccatat tgatgctcat gctgatttgc gcgaacaata tgaaggcgag
    11281 gcgctatccc attctacgcc gatccgcaaa gcgtgtgagc tgattggagc cgagaacgtt
    11341 tattcatttg gcatccgttc aggcatgcgc gaagaatttg cttacgcaaa ggaagcaggc
    11401 atgcatcttt acaaatttga cgtggcagag ccgttaaaaa acgtgctgcc ccatctatca
    11461 gggcggcccg tttacattac gattgacatt gacgtattgg atccggcaca cgcgcctggc
    11521 acagggacag ctgaagctgg tgggattacg tcaaaagagc tgcttgaagc gcaaatgctg
    11581 ctttcccaag cagacattca aattgtaggc gctgatctcg tggaagtggc accagcttat
    11641 gatccgactg agcaaaccgc cattgctgcc agcaaatttg tacgtgagat gcttcttggt
    11701 tgggtgcata aaaagtaaag aaacaagagc tgcagattgc aacatgtccc taaacccagt
    11761 aaaataggaa aaagaacgcg cttcgcggat ttgtgtgtgg ctggcagatc atatagaatg
    11821 gatgttttga tgaatgaagc ggaaagtgaa aatctctttt caaaccacaa catttataaa
    11881 agggcaacag ccggatgcgt tctcgtttga tacggaaggc gacctttata taaaagggag
    11941 tgcctcgtat ttgcgcttta aagaaacaca tgcccataaa caggatgtat tttcaacgat
    12001 gaaatgggac ggccgcgagc tcatgctcat ccggcaaggg acgatcatta tgcggcaaag
    12061 ttttcttgca aaagaagaaa cgtatggacg gtatgtcacg cctgaagctt catgggaaac
    12121 aaaagcacgg acagatacat tgcttgtgca gctgccgaca ggagctaagc aaaagggcag
    12181 aatttatgtg cgctaccaat tctttttgca aggccagcta acgggagagc atgaaatccg
    12241 attggcaatg aaacaaattg aataggtcag aacaggataa tacaaggaat gtgccaatca
    12301 tccttgtatt tttttgctct gaaaggcaga agcccttgaa gctcgttgcc tgattcggct
    12361 aaactacgga tagacgagtc ggtttcagcc atttactaat ccatagctag aaacgtggat
    12421 ggggagcact tgatggaatg gataccaatt agagacaaat aaggagctta tgaagaatga
    12481 accatatgga acgcaaaaaa gaacagctgc gcatggaagt gcgccgtgcc gttttacagg
    12541 cggaacttgc tacagaatca gaagtgccgt ccgtcctttt ggaagtgcca aaggacaaag
    12601 cgcatggcga ctttgccacg aatatcgcca tgcagcttgc gcggatcgct aaaaaggcgc
    12661 cgcgggctat tgcagaagag ctagtggcca actttgaccg tgaacaggca ggcattgaaa
    12721 aaatcgaaat cgctggccct ggctttatta atttcttttt ggataatggc tatttgcgtg
    12781 aattgatccc gcaagtgcta gacgaaaaag atgattatgg gcgcagtgac gtggggcaag
    12841 gcgagaaagt gctcattgaa tttgtatcag ccaatccaac aggagacttg catttaggcc
    12901 acgcccgcgg ggcggcagtc ggcgacacaa tcgccaatat tatggaaaag gctggctaca
    12961 aagtgtcacg ggagtattac attaatgacg cgggcaacca aatcgaaaac ttggcagcct
    13021 ctttaaacgc ccgctatttg caagcgctcg gagaagagaa accaatgcca gaagacggtt
    13081 accacggcca agacattatc gatattgcca agcagcttgt cgacgaagtt ggcgatcaat
    13141 atcgccaaat ggatgagaaa gagcggttgg catttatgcg tgaatacggc ttgaaaaaag
    13201 agctggaaaa aattaagcaa gacttaaacg cataccgcgt tgaattcgac aaatggtttt
    13261 ctgagacgtc tttgtatgaa tcagggcaag tcaagcgggg cttgcaagtc cttaaagata
    13321 aaaatgaaac ttacgaaaag gacggggcga cttggctacg ctcaactgct tacggcgatg
    13381 acaaagaccg ggtgcttgtg aaacaagacg gtacgtatac gtatttaacg cctgacattt
    13441 cgtaccatct tgataaattt gaccgtgggt atgaccgttt aattgatgtg ctaggtgccg
    13501 accatcacgg atacattcca agaatgcggg cggcgattca agcgcttggt tatgatccgg
    13561 atcggtttaa cgtacagatt atccaaatgg taagcctgtt ccaaggcggc gaaaaagtta
    13621 aaatgagcaa gcgcacgggc aaagcggtga cgttgcgtga attgatggaa gaggttggcg
    13681 ttgatgcgac gcggtatttc tttgcgatgc gtagcccaga tactcatctt gatttcgata
    13741 tggacttagc tgtgtcaaag tcaaatgaaa accctgttta ttacattcaa tacgcacatg
    13801 cacgggtatg cagcattctt cgccaaggag aagagctagg catcccttat agtgcaaaca
    13861 cggatttgtc gccgatagca agcgaaaaag aatatgagtt gctaaaagca attggcgagt
    13921 ttcctggtgc tgtggcagaa gctgcaacaa agcaaattcc acagcgcatt gctaattatg
    13981 cctatgattt ggcgcaagcg ctccacagtt tttataatgt gacgcgcgtc attgatacag
    14041 aaaacaagga cttgtctgca gcgcgtttgg cattgatgaa agcgacgcaa atgactatta
    14101 aaaatgcgct cgccctgcta ggggtggaag cgccagagaa gatgtagcca tggatacatt
    14161 atggtggctg gtgattgccg tttttttcat tgccagtttt gttggtttaa tcgtaccgat
    14221 tattccctct gtcctcgtgt tatggggcgg ttttctcgtc tatgtgtttg ctttagaggg
    14281 cagcttgagc gttgtgtttt gggtaggcat ggcagtgctt actgtgttct tgcttgtcgt
    14341 tgacttgctt gccaacatgg cgttcgtcaa gcggacaggc ggttctaaat ggggggaacg
    14401 ggcagcgttg gtcggcgtta ttgttggtgc atttgttgtt ccgccgttcg gtttgatcat
    14461 cgtcccgttt gtgcttgttc tcatagccga actcttgcaa aagcagccgt ttgaaaaggc
    14521 agtacgaatc gcatttgcct cttttctcgc ttttataagc ggcacgcttg ctaaagcggt
    14581 tgtccaaatt gtaatgattg cctggttttt gattgaagta ctctagcagc tgggccaaaa
    14641 gaaagagtgg caaccacctt gtatggtggt tgccactctt tttgtgaaaa gaaaaccccg
    14701 ggctcggccc ggggttccaa aaagc
//
