LOCUS       gnlProkkaPMCCECLB_57   14829 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PMCCECLB_57.
ACCESSION   gnlProkkaPMCCECLB_57
VERSION     gnlProkkaPMCCECLB_57
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 05:07:57
            Original ID  :: gnl|Prokka|PMCCECLB_57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14829
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14829
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4298:10392]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4299..10392
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14829
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14829
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(61..1023)
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="MNINKIFLLNFNDTNDFNIKQVAIENDKVVSFSKSIKNISEYGMK
                     NYFDLAESLENPKKYSISLGENDEKTYHIDLLEKIRSSLDEADFLENIELAVDNGKLLY
                     NIAIYVEDDEKYTGIYIYEIKESHLLRDDFYVMKIPFTKQKINLKKKGAGTTNEKLAVV
                     ENVAGSVGLPTEGCIVSFFKRKKDDEQYKIYKVKVYDAWKFDDVFGKVETRKKYVRFTL
                     EKFANEENPIKIANDAVQVVFKNEDEETSNVVDTVEAVIMSDMKLVKTFSNFHNNSRRK
                     IKNIEVSRLREVLNLLKDYVLNNAEANFELKNGSVTTNG"
     CDS             complement(1028..1657)
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MFRSSSEKFKLYYYVSSLFPIHISVLVFIFSSKLENNNCENLFKV
                     SSTSSKITILIMLLSILVDLYSLVRVIQLLNNQKKLTKALGTNSVRISNEYNGGLRDFL
                     LSFIVPAITTFSADENPLTMIIFILLFQFIVYVFYKNSSDFFPNISLMFMGYSVFKVDT
                     YDLGGIEYVFGKTKNIDDIILKKVDVIMIGDKNYPNNVAIILEKKV"
     CDS             complement(2002..2406)
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MKKVLVDTCVIIDILLDREKFVDDSYSAVSKLIRKGDTICTTAKA
                     MTDIFYIVHHSLHDNDKTKEVLLKLSRVYQILDTKEKDTIMAITSDVADYEDAVMVETA
                     IANKVDFILTRNIKDYKKAKIKVISPTELN"
     CDS             complement(2406..2627)
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MTQVTATELKNNLGKYLKKSEFEDIYITKNGVIVSVLSNPNQSKL
                     QMLDDLKGIAPDMNMTDEELRSERISNI"
     CDS             complement(3070..4218)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 56.4; E-value:
                     3.8e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSARFRNFSTMIIIPFTILLLAVVIFSFFGKKEI
                     TIQGAGTLEALGNNPVIQSTVNSPIEKNYLKEGKYVKKGDTLLVYNNVNIQDKGKLYNS
                     QKEILDRQLAALNLLKQGVQDNHDSFGEDDEFGYRNDLKSYLQQRNTYLTENTMIQDKS
                     KNDKAKQSSINNELKKQGGSATSIADFDSSKYDIDINNQKMSDLQSSKLSSIDQEIIKI
                     KQNISELNANIDENNNTNREYKVKAVRDGILHINDEYSESHYISAGANLAQILPILKNQ
                     KTLKIKAYISTADISSIKVGQKVRFKVTRNVPKPIILTGKIHKISISPVEIGKENYYQI
                     EAKTDIQNTNRDLLKYGMQGQMVVITGKTTFFEYYKDKLFNR"
     CDS             complement(4299..6392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 296.4; E-value:
                     6.9e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_6"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.3e-45, bitscore:
                     143.7, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1045.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKYKKYYIPQVDESDCGVASLAMILKHYGSSLSLAYLRNIAKT
                     TMEGTTALGLVKTAQTLGMETQAVKADMSLFGMKDITYPFIVHVVKEETLLHYYVVLKA
                     TPNYILIADPAPDVGITKMSYERFEKEWTGITLFIVPGIEYKPTKETRQSLISLFSKLF
                     KQKQLIVNIVLAALLITIISILGSYFLQGIIDTYIPNGMHSTLAIIAFGLLVIYVFNSI
                     FTYARDFLLAILGQRLSIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVVSIFLDVSIVVIMGIILAIQNLKLLGITLISLPIYTIIILTFTKAFERLNNKQMES
                     NAILSSSIIEDIQGIETIKALNSEQMRYRKIDSQFVDYLRKSLAYIKTDSLQQALKLFI
                     QQTLNVIVLWLGANLVISNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDRKAVHDVTQLQGNIIFQDVDYRYGYGENILDKVNLTLKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFAPVSGSIKLNNHDINNIDKHTLRSYINYIPQNPYIFAGTIE
                     DNLRLGNRSNVTDEDILMACKIAMIDTDIAKMPLQLKTKLDENANILSGGQKQRITIAR
                     ALLSPAQVLIFDESTSGLDAITEKKLIDNLMKLKSKTIIFIAHRLSIAKRTNNILVLDG
                     GKL"
     CDS             complement(6603..6800)
                     /locus_tag="ctg48_7"
                     /transl_table=11
                     /translation="MKINKKFYKNYTFYIGLVMLSIAVGSIFLDKGYFLFTIIDILFTC
                     LGIKYVYQSLVLTKRYERNR"
     CDS             complement(7045..7284)
                     /locus_tag="ctg48_8"
                     /transl_table=11
                     /translation="MVEIGIIILLVVGFMVISRLKVNFTKNSRYAGFLLLILLDLNGLM
                     RTPMLTVRGLILLGTLMIFVIMLIKEIRQNRKYS"
     CDS             complement(7321..8115)
                     /locus_tag="ctg48_9"
                     /transl_table=11
                     /translation="MEEYGIIICDDEKDQVRRIHDLVKYAIWSLEDSADSKDKEFKITL
                     EANSYIEVADYLEDNKVDSGVYFLDIELSRDKADRDGIDLAEFIRQRDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDSDEVIQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDILYIITTPKSHRLEIVTVNGMGEFTGDIKKLEAENDFLEKISQSCLANPS
                     NIVKINLSTRVISFKDGYKETFPRRSKAKMKSLIERYNLKTV"
     CDS             complement(8129..9421)
                     /locus_tag="ctg48_10"
                     /transl_table=11
                     /translation="MTDIVDIYNRYNIIIYAVGLFISVACDYLFFYLITPINRSKKQNI
                     LFTIITFPIVFLYHGGGDLGAFCAELFEVSAFYIVYKRRKRDYQVLGRILILLLYSYLS
                     FEIEFLLSQIISQYISALPIDTIVINILEYYILMKTDIIKNLDDEYGKTFFYLIIYLLV
                     SFVGIYYLTGYLFKVDKVLYLILLVVIIVQLIFSLYIYNNSKKIRQDKLSLQQIKDLKI
                     YTQQLESSQRSLRKFKHDYQNMLVSLKLSAKKNHDKELIDKLAEYSSKILEDKVLWQFN
                     DVDNIKDELLKSLFISKLNRIFQDNIQYSFECRDVIDSLSNEYNAFDIIRILGITYDNA
                     IEESLELGDEARIDTMVYRENGELEIEIKNRCRNTDLTIQDMKKSGFTTKKNHDGLGLA
                     NIEELSQPYNDIFINYQIKDGWFTFLMVMSI"
     CDS             complement(9423..9542)
                     /locus_tag="ctg48_11"
                     /transl_table=11
                     /translation="MKFEVLTEKKLQVIVGGKQEGGTKTYDKVCRFKFLGICK"
     CDS             complement(9974..10180)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_12"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.2e-12,
                     bitscore: 36.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLDKRFTIMTEDNLASVNGGKNGYGGSGNRWVHCGAGIVGGAL
                     IGAIGGPWSAVAGGISGGFASCH"
     CDS             complement(10198..10392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_13"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.1e-17,
                     bitscore: 53.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKEFTVLTECELAKVDGGKRGPNCVGNFLGGLFAGAAAGVPLGP
                     AGIVGGANLGMVGGALTCL"
     CDS             complement(10398..10655)
                     /locus_tag="ctg48_14"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEDMS
                     YLDYIQTPKMIIVAIFCLIGGSTLLYLLDTTMKVNKHMKG"
     CDS             complement(10785..10958)
                     /locus_tag="ctg48_15"
                     /transl_table=11
                     /translation="MNNNFVQIDKKELAHIIGGRNSYDYIDSGKFGYDIGCTIANTKFF
                     KRLRHSNQNICS"
     CDS             11191..11454
                     /locus_tag="ctg48_16"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLFLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFEATDDKHPLNRIDFGLQLLFIFISIIKFFLISGR"
     CDS             complement(11493..11822)
                     /locus_tag="ctg48_17"
                     /transl_table=11
                     /translation="MKAIYKGKEVQIWQISKTAEQPEWIKAAFKANYLKWSGDKLLFIM
                     NGVKAPVKISAWTNFKTLFNGASGWWATYASGYIGDYLDFTNRKIISERKFKKKYKIVD
                     TYVNK"
     CDS             12044..13018
                     /locus_tag="ctg48_18"
                     /transl_table=11
                     /translation="MRYIKFTLLIYSFLLTWGITTNSISADEVTPTTTSETTVTPQSQS
                     TSVDSNDEDAAIEEKFYSHDVTIDEYNQNVANFNKVNTDTVKTMVTENSNNLDQVLYIG
                     RPTCYFCRQASPHLRDFNQLINNQLYYYDIDAEPSAHDFAFKEIGIPGTPTTMRLKNGK
                     VVSAWIGGEKTGQEFYDFLFSADANKLADSYTIKKTVSTDTSNPVITNNQNVEPTVKHI
                     PTNISQLKEEKTTTELVNTTSQPFKPVKKIQNPATTTNKKNKNSVLPQLGVVPLYHQPL
                     FKLPIPKIPKQLERTIMLITFLVLYLGFLICLWLSWKEINKRK"
     CDS             complement(13181..13831)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 127.6; E-value: 8.9e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_19"
                     /transl_table=11
                     /translation="MIKAAIFDLDGLLVDTEIVSLKIYQELLSEYGYSFTKEEYAKHYS
                     GKTEKENIKRFIDTYNLSVSYQECLDEVLNIERKLISQGVELKVGVKSLLMYLKENNYK
                     VTLATSSTKDRAISILKGHDILSYFDEFVFSEDVTLSKPNPEVFLKACEKTNVSTNEAI
                     VLEDSENGIMAAYNAHIPVICIPDMKRPAKEYLEKTIAVCKTLNDVIDYLKTK"
     CDS             complement(13942..14283)
                     /locus_tag="ctg48_20"
                     /transl_table=11
                     /translation="MKAIYRGRKVDVWQVSRDNVQPDWVKDAFEHNGLRWLHGSGNKVR
                     IYWPAVTRAKKGIIRTILNGISASFVSIAGGSASMYDIGFEGDVIDFTNSKVVTAEKFA
                     KKYRIVSED"
     CDS             complement(14304..14570)
                     /locus_tag="ctg48_21"
                     /transl_table=11
                     /translation="MDYLVIKTIIWIFFITSAILEVNYKKKHGELDKRARKQAILGTFL
                     IVTTIFDEGYENKILYIIVLIALLVYIVLVIYRLVMAIKDRKK"
ORIGIN
        1 aattacctcc ttcggtggta ctgtttctta ctattattat acgctatttc tcgtcaaaaa
       61 tcaaccattt gttgtgacag agccattttt taattcaaaa tttgcttcag cattattcag
      121 tacataatct tttagtaaat ttaatacttc tcttaatcta gaaacttcta tatttttaat
      181 cttacgtcta gaattattat ggaaattcga aaaagttttt actaatttca tatctgacat
      241 aattactgct tctaccgtat ctactacatt agaggtttct tcatcttcat tcttaaatac
      301 tacttgaaca gcatcattcg ctatttttat aggattttcc tcattcgcga atttttccag
      361 tgtgaatctt acatacttct ttcgagtttc tacttttccg aaaacatcgt caaatttcca
      421 tgcatcataa actttaacct tatatatttt gtattgttca tcatcttttt tgcgtttaaa
      481 aaagctaact atacatccct ctgtgggcaa ccctacagag cctgccacat tttctactac
      541 cgctaatttt tcatttgtag ttcctgctcc cttctttttt aagttaattt tttgtttagt
      601 aaatggtatt ttcatcacat aaaaatcatc tcttaataaa tgactttctt ttatttcgta
      661 aatataaatt ccagtatatt tttcatcatc ttcaacatat attgcaatat tgtacaataa
      721 ttttccgtta tcaaccgcta attcaatatt ttctagaaaa tccgcctcat ctaaagaaga
      781 ccttattttt tctaataagt caatatgata tgttttttca tcattttcgc ctaaacttat
      841 agaatatttt ttaggattct ctaaagattc agctaaatca aaatagttct tcattccata
      901 ttctgaaata ttcttaattg atttagaaaa agaaactact ttgtcatttt ctatcgcaac
      961 ttgctttata ttaaagtcat ttgtatcgtt gaaatttagc aaaaatattt tatttatgtt
     1021 catgtaatca cacctttttt tcaagaataa ttgctacatt attagggtag tttttatcac
     1081 ctatcataat cacatctact ttttttaaaa taatatcatc aatatttttt gtctttccaa
     1141 aaacatactc tatacctccc aaatcatatg tatcaacttt aaaaacagaa tatcccataa
     1201 acattaatga aatatttgga aaaaagtcgg aagaattttt gtaaaataca tatacgataa
     1261 attgaaaaag taaaataaat ataatcatag ttaatggatt ctcatcagct gaaaatgttg
     1321 ttattgcagg tacaataaaa ctaagcagaa aatcccttaa tccaccatta tattcattag
     1381 aaattctaac actattagta cctaatgctt tagttaattt cttttggtta ttcaataact
     1441 gaataacacg aactaacgaa tataaatcta ctaatattga caacaacatt attaatattg
     1501 taatttttga cgaggtagat gacactttaa acaaattctc acaattgtta ttttctagtt
     1561 tagaagaaaa tataaatact aatactgaga tatgtatcgg aaacaacgag gacacataat
     1621 aatagagctt aaatttctca ctagaggatc taaacatagt tttttaattg ccctcctttc
     1681 ttcaaaacat taaacagtac taaatataca ataagtataa caaaatagta ttactttttg
     1741 taacacaaat ttaatcaatt aaaatctaaa aaatgccact cctacaaaga agtgacaaag
     1801 acaactatat acccgatatg ctatactaga tagcgaaaaa ttaaaaagta acttgcagaa
     1861 aacgtttctt tagagagaaa ctctggaagt tatctttata atgataagtt agataactgt
     1921 tagatagtaa aacggttact tatagacaat aaaaaatctc ttcatttaaa aggagattct
     1981 gcatttcttt ttaggataaa tttaattaag ctctgttgga ctaatcactt ttattttagc
     2041 tttcttataa tctttaatat ttctcgttaa aataaaatcc accttgttag caatggccgt
     2101 ttcaaccata acagcgtcct cataatcagc tacgtcagaa gtgattgcca ttatggtatc
     2161 tttttctttg gtatcaagga tctgatagac tctacttaac tttaacaaga cttctttagt
     2221 tttatcatta tcgtgtaatg aatgatgtac aatataaaaa atatctgtca ttgccttagc
     2281 tgtcgtacaa atagtatcgc ccttccttat taacttagaa acagcgctat aactatcatc
     2341 aacaaatttt tctctatcca aaagaatatc aataataaca cacgtatcaa ctaaaacttt
     2401 tttcatcaga tattactaat cctttcactt cttagttcct catctgtcat attcatatct
     2461 ggtgcaattc cttttaagtc atctaacatt tgcagtttac tttgatttgg attagataaa
     2521 actgatacaa ttactccatt tttagtaatg tatatatctt caaattctga cttttttaaa
     2581 tacttaccga gattattctt taattcagtt gctgtaactt gtgtcattta aaccacctcc
     2641 acaaattaat tataccacaa attagctaat catatagtaa aaacagctaa tactaaatat
     2701 aaaattagct aaatacgaat tatattaact attgcttaaa aacaacaccc atcaaaaaaa
     2761 tcccatcagt atctactacc atgaactttt tatttatcaa cattacctct accaataata
     2821 ttaagaataa aaccaaatac tttccatgat aataacttcc tttgtataat gtgatgttgc
     2881 tatattcatt aatgcaacta cattaatttt tttgaattga tatatactaa aaaatattat
     2941 aattcctatt gataaaaaga aaaaatctaa tatttcaaaa tttaaattat ctccaccctc
     3001 atcttaaaaa gagctgaaga tattccagct ctcacaaata ttttatccag taaaggcgta
     3061 caaattaatc tatctattaa acaacttatc cttataatat tcaaaaaatg ttgtcttacc
     3121 tgtaattaca accatttgcc cttgcatacc atacttcaat aaatccctat tggtattttg
     3181 aatatctgtt ttagcttcaa tttgataata attttctttc cctatctcta ctggagaaat
     3241 cgatatctta tgtatttttc cagtcaaaat aataggttta ggtacatttc tagttacttt
     3301 gaatcttact ttttgcccta cttttatgga agaaatatct gctgtactta tatatgcctt
     3361 tatctttaaa gttttttgat tcttcaaaat cggcagtatc tgagctaaat tagcccctgc
     3421 acttatataa tgactttcac tatactcatc gttaatatgt aaaattccgt ctctaacagc
     3481 ctttacctta tactctctat tagtattatt attttcatca atattagcgt tcaattctga
     3541 tatattttgc ttgattttta taatttcttg atcaatagaa cttaacttac ttgactgtaa
     3601 atcactcatt ttttgattgt ttatatcaat atcgtattta gacgaatcaa aatcagctat
     3661 acttgtagca gacccacctt gtttcttcaa ctcgttatta atcgaacttt gtttggcttt
     3721 atcgttttta gatttatcct ggatcattgt attttctgtt aaatacgtat tcctttgttg
     3781 taggtaactc tttaaatcat tacggtaacc aaattcatca tcttccccaa aagaatcatg
     3841 attgtcttga acaccttgtt taagtaagtt caaagctgcc aactgtctat ctaagatttc
     3901 tttttgtgaa ttatacagtt tccccttatc ttgtatattc acattattat aaacaagtaa
     3961 tgtatctcct ttttttacat actttccttc ttttaaataa tttttttcaa taggactatt
     4021 tacagttgat tgaataacag gattatttcc caatgcctca agcgttcctg caccttggat
     4081 agttatctcc ttttttccaa aaaagctaaa aattactacc gccaacaata aaattgtaaa
     4141 aggaataata atcatagttg aaaagtttct aaatctagct gaataaaatt cgctactttc
     4201 taaaaattta tcttccataa tacaatactc cccctaacta ttaattaaat tgtagtaata
     4261 tcctttttta gctaataatt catcatgtct acccttttct acaattttcc gccatctaat
     4321 actagaatat tatttgttcg cttagctata gataatctat gtgcgataaa aattatagtt
     4381 tttgacttta atttcattaa attatcaatt agttttttct ccgtaatggc atctaatcca
     4441 cttgtagatt catcaaaaat taatacttgt gctggagata ataaggctct agcaattgta
     4501 attctttgtt tttgtccacc tgataagata ttagcatttt catctagttt agttttcaat
     4561 tgtagtggca tcttcgctat atctgtatca atcattgcta ttttacaagc catgagaata
     4621 tcctcatcag ttacattaga tcgattacct agtctaagat tatcttctat tgtcccagca
     4681 aaaatatatg gattctgtgg tatgtaatta atataagaac gcagagtatg cttatcaatg
     4741 ttatttatat catgattatt tagttttata ctacctgaaa ctggggcaaa aaaattcacc
     4801 aatagtttaa ctaacgttga tttgccagag ccactcatac ctactatagt tagtttttct
     4861 ccctgtttta aagtcaaatt aaccttatcc aaaatatttt caccatatcc atagcgatag
     4921 tcaacatctt gaaatataat atttccttga agttgagtga catcatgaac agcttttcta
     4981 tctttaaatt cactttcaac taagtaaacc tcattcaaac gattgtgagc tacccttgca
     5041 ctctgcaatt ttggctgtaa atttatgata ttttgtaacg gattcacaaa ataacttaat
     5101 agtgcgttaa aagtcattaa ttgtcctata gagagttgat tactaattac cagatttgcc
     5161 cctaaccata ggactataac atttaatgtt tgttgaataa ataactttag tgcttgttgc
     5221 aacgagtctg tttttatata tgctaacgat ttacgcaaat agtccacaaa ttgactatca
     5281 attttgcgat aacgcatttg ttcgctgttt aaggctttta ttgtttctat tccttgaata
     5341 tcttcaataa tagatgaact aagtatcgca ttactttcca tttgtttatt attcaatctt
     5401 tcaaatgctt ttgtaaatgt aagaataata atcgtgtaaa ttggaagtga gataagagtt
     5461 atccctaata atttaagatt ttgaatagcc aagattattc ccataataac cacaatgctt
     5521 acatctaaaa aaatagatac tacagtgctt gctaaagcat ctataatttt actagcatca
     5581 ttaaaacgag agactatttc cccagttttt ctggtcgcaa aaaattccat aggcaactca
     5641 aaaatatgtc taatataact taaaataatt tcaatcgaaa gtcgttgtcc taaaattgct
     5701 aataaaaaat cccttgcata tgtaaaaatt gaattgaaca catatattac tagtaatcca
     5761 aaagcaataa ttgccagtgt actatgcata ccattaggaa tatatgtatc aattattccc
     5821 tgtaaaaaat atgatcccaa tatactaata attgtaatta acaaagctgc caatacaata
     5881 ttaactatta gttgcttttg cttaaataat ttactaaata gtgatattaa tgattgtcta
     5941 gtctcttttg tcggcttata ttcaattcct ggaacgatga ataaagtaat tcctgtccat
     6001 tctttttcaa aacgttcata cgacatttta gttatcccta catctggagc tggatcagca
     6061 attaaaatat aattaggtgt tgctttcaat actacataat aatgtaataa cgtctcttct
     6121 ttaaccacat gtacaataaa tggatatgta atgtctttca ttccaaaaag agacatatca
     6181 gcttttacgg cttgtgtttc cattcctaaa gtctgtgctg tcttaacaag acctaaagct
     6241 gtagtcccct ccattgttgt cttagcaatg tttcttaaat acgctaatga tagcgatgat
     6301 ccatagtgtt tcaaaatcat agccaacgaa gctacgccac aatcagactc gtctacttgt
     6361 gggatataat attttttgta tttatgtatc ataagttaat atccccctat taaacttatt
     6421 atctttcatc tcttttatta agcatatcat gttcttaaat tatcttgcct aaatcatcaa
     6481 atctggtcct ttttatactt atttggtatt agtattttct ttaacttgtt aaaataaaaa
     6541 gctaaaaaaa tcattgagta aattttaatt tgatttttcc tagctttctt aatttattaa
     6601 ttttaacgat ttctttcata acgctttgtt agcaccaatg attgatagac atattttata
     6661 cctaggcaag taaataatat gtcaataatt gtaaataaaa aatatccttt atcaagaaaa
     6721 atacttccta ccgctattga taacattact aaaccgatat aaaaagtata atttttataa
     6781 aactttttat ttattttcat atactactcc ccatttccac taataatttc agctagattt
     6841 ttccattata caatttcatt tcctagcctt aatttatcat attcttaaat cattgtgtct
     6901 aaattatcaa atttggtctt tttttagatt tatttggata ctaaaagtgt tgttaaaatg
     6961 tagattagtc aataatcatt tgcaaagata atcatgaatg tcatataaag aggattggaa
     7021 taccctaagt tccaaccctc tttattaact atattttcta ttttgtctaa tttctttaat
     7081 caacataatc acaaaaatca tcaatgttcc caataagatt aaacctctta ctgttaacat
     7141 aggagttcgc ataagtccat ttagatccag taatattaac aataaaaagc ctgcatatct
     7201 actatttttt gtaaaattta ctttcaacct tgaaattacc ataaacccta caactagtaa
     7261 tatgataata cctatttcta ccatgtcatt ttcaccacct atatcaataa aaacaaaaga
     7321 ttaaactgtt ttcaaattat acctttcaat caaacttttc attttagcct tacttcttct
     7381 aggaaaagtc tctttatatc catctttaaa agaaataacc cttgttgaca gattaatttt
     7441 aacaatatta cttggattag ctaaacaaga ttgtgatatt ttttctagaa aatcattttc
     7501 tgcctctaac ttcttaatat cgcctgtaaa ctcacccata ccattaactg taactatttc
     7561 taatctatgt gacttaggag tggtaataat atatagaata tcattaatat tttcgttaat
     7621 aattcttctg cccattttat agctaaatgt cattttcttt atggcatgag attccctaat
     7681 tctccttgca gctaatgata aagtctcatt tagtcgcttt tgaatcactt catcactatc
     7741 atttttagta ataaaatcta acgctcctgt gcgacgtcga taggtcattg ctgctagatt
     7801 ttcataagct gtaataaaaa ttatctgtgc atttggatct ctttgtctaa taaattcagc
     7861 taagtctatt ccatctctat ctgctttatc cctactaagc tcgatatcta aaaaataaac
     7921 tccactatct actttattat cttctaaata gtcagctact tcaatataac tattagcttc
     7981 caaagttatt ttaaactctt tatctttact gtcagcagaa tcttctaaag accaaatagc
     8041 atatttaact aaatcatgta tccttctaac ttgatccttc tcatcgtcac aaataataat
     8101 tccatattct tccaaattaa actacccctt aaatactcat aaccataagg aaagtaaacc
     8161 aaccatcttt aatttgataa ttgataaaaa tatcattata aggttgactt aattcttcta
     8221 tattagctaa tcctaatcca tcatgattct tcttagttgt aaaacccgat tttttcatat
     8281 cttgaattgt taagtctgta tttcgacaac gattcttaat ttctatttca agctcaccat
     8341 tctctcgata aaccattgta tctatcctag cttcatcgcc aagttcaaga ctttcttcaa
     8401 ttgcattatc atacgtaatc cctaatattc taattatatc aaatgcatta tactcattcg
     8461 ataaactatc tatcacatcc cgacattcaa aagagtattg aatattatct tgaaagattc
     8521 tattcaattt actgataaat agactcttta ataattcatc tttaatgttg tcaacatcat
     8581 taaactgcca taatacttta tcttctaaga tcttactcga atattcagct agtttatcta
     8641 ttaactcttt atcatgattt ttctttgcac tgagcttcaa acttactaac atattttggt
     8701 agtcatgctt aaatttgcgt aaacttcgct ggctactttc taactgttga gtgtaaatct
     8761 ttaaatcttt aatttgctgt aaacttaatt tatcttgtct aattttttta ctattattgt
     8821 agatatatag tgagaaaatt aattgtacga taataactac taataatata agatataaca
     8881 ccttatcaac tttaaataaa taaccagtca aataatatat tcctacaaaa ctgactaata
     8941 aataaataat taaatagaag aatgtcttcc catattcatc atctaaattc tttataatat
     9001 ctgttttcat taaaatatag tattctaaaa tatttataac aatagtgtct attggaagtg
     9061 cgctgatgta ttgtgaaatt atttgtgaaa gtaaaaattc tatctcaaat gaaagatatg
     9121 aatatagtag gagaattaat attcttccca atacctgata atctcttttt cttcttttat
     9181 atactatata aaaagccgat acttcaaaaa gttcggcaca aaaagcacct aaatctccac
     9241 ctccatgata caaaaaaact atcggaaatg taataattgt aaatagaata ttttgctttt
     9301 tacttctatt aatgggtgta attaaataga aaaatagata gtcacatgct acactaataa
     9361 ataaaccaac tgcatatatt ataatattat atctattata tatatccact atatctgtca
     9421 ttttacttgc aaattcctaa aaatttaaac ctacatactt tatcataagt ttttgttcct
     9481 ccctcttgtt taccacctac aataacttgt aacttctttt ctgttaacac ttcaaatttc
     9541 ataaaaaatc tctcccttgt tatctttatt acaaatatag tttaacattt tttaatctac
     9601 tttattcgtt ttttatcata ttcggttcat tttaatgctt atttggatga aattcttaaa
     9661 actatagcct atagccacca cataaagttt aacacccatg cctcacataa cctactttct
     9721 tattcttttc tatagctttc tcatcaaatg acttgtaatg tctatcttct tttttactag
     9781 tatagatact gataaagata atatatacaa ctattactgt aacctaaatt atcatgtact
     9841 tatttcctaa ttcccaaaat atattatatt ctattaaaaa taaaagtagt gtcaaattta
     9901 gctatatact ataacttaca cttgacacta cttgcagaaa aatagatcta ttttctaatt
     9961 ttttatattt atattaatgg caacttgcaa atccaccaga aattccaccc gctacggctg
    10021 accaaggtcc accgatagct ccaattaaag ctccacctac gataccagct ccacagtgaa
    10081 cccagcgatt tccgctacca ccataaccat ttttaccacc atttactgat gctaagttat
    10141 cttcagtcat aattgtgaat cttttatcta gatttttcat tttaaatcac tcctatatta
    10201 taaacaagta agcgctccgc ctaccattcc taagtttgct ccacctacaa taccagctgg
    10261 tccaagtgga actcctgcag ctgctccagc aaatagacca cctaagaagt tacctacaca
    10321 gttaggtcca cgtttcccac catcaacctt tgctaattca cattctgtca atactgtaaa
    10381 ttccttcatc atgataatca tcctttcata tgtttattta ccttcattgt agtatctaat
    10441 aaataaagta gtgtactacc acctattaga caaaaaatag caactattat cattttaggc
    10501 gtctggatat aatctaaata agacatgtcc tcattaccaa acaaccatat tcctagtgga
    10561 atcaatagtg cccaaataac tggagcaata acatatctct tctttcctct aatgaatcca
    10621 ccatccaacc aagtctccca tagttttttt agcatgtaaa aacacatcct ttctaaaaca
    10681 cttgtgaaac atatacttac acttttattg tattatcatt ctgtattcaa atatcaattt
    10741 agcgtaaaat acgttattct atacctagtt ggttacattt ctttttaact acaaatattt
    10801 tgatttgaat gtctcaatct tttgaaaaat ttggtattag cgattgtaca tcctatatca
    10861 taaccaaact taccactatc tatatagtca taagaatttc ttccaccaat tatatgtgcc
    10921 aattctttct tatcaatttg tacaaaatta ttattcataa cttcaacacc tcataatttt
    10981 taaaaattta ttatagctat aatttacact tatgattatt cacttcatct gctctttttg
    11041 attatttctt ctaattttgc taaattttat tcttattctc ttttttcaac cagataggca
    11101 ctatttatta ccaaattgga aaaatctcct caatttatta ctttctatgt aataataaaa
    11161 atacttttat aatgaattga ggtaaaaatt atgaatagtt tttctaataa tattaatttc
    11221 agcaaaattt ctgtttcact aattacttta ttcctattga tctggacatt agttgatgga
    11281 aatctaattc atcttggtat actagccttt tcttctttgg ttacaaccat gctacatttc
    11341 cattattttg aagctactga tgacaagcat ccactaaata gaattgattt tggattacaa
    11401 ttgctattta tctttatttc tattattaaa tttttcttga tttcaggaag ataacaataa
    11461 gcctatcagg tatcaaatta catctgatag gcttatttat taacatatgt atcaacaatt
    11521 ttgtacttct ttttaaattt tctttctgat ataatttttc gattagtgaa atccaagtaa
    11581 tcgcctatat acccacttgc ataagttgcc caccaacctg aagctccatt aaataaagtc
    11641 ttaaagttcg tccaagcact aattttaaca ggtgccttaa ctccattcat aataaataac
    11701 aatttatcac ctgaccactt tagatagtta gctttaaatg ctgcttttat ccattcgggt
    11761 tgttctgctg ttttacttat ctgccatatt tgtacttctt tacctttata gattgctttc
    11821 atagaaatca ccttctacat ataattaaag agctctatta attacatctt cattatacta
    11881 ttttcataat acatccaatg ctaaatttct taactagcac tatttcttac ttatttggta
    11941 aatagtccaa ataagtagtt attgctacca ttccagcagt ttatcacact atgtagacat
    12001 tatttgcaat aattacatat atacgattag ggggattgaa aaaatgagat acattaaatt
    12061 tactttacta atatattctt ttttactaac ttggggaatc accacgaata gtatatcagc
    12121 ggatgaagtt acacctacta caacatccga aacaacagtt acgcctcaaa gtcaaagtac
    12181 atctgttgat tctaatgatg aagatgctgc aattgaagaa aaattttact ctcatgatgt
    12241 tacaatcgat gaatataatc aaaatgtggc aaacttcaat aaagttaata ctgatactgt
    12301 taaaaccatg gttactgaaa atagcaacaa tttagaccaa gttctttaca ttggacgtcc
    12361 tacttgttat ttttgtcgac aagcttcacc acacctacgt gattttaatc aactaataaa
    12421 taatcagctt tactactatg atattgatgc tgaacctagt gctcatgact ttgcgtttaa
    12481 agaaattgga attcctggaa cacctacaac tatgcgttta aagaatggta aagttgtcag
    12541 tgcttggatt ggtggcgaaa aaacaggaca agaattttat gactttttat tttctgcaga
    12601 tgctaacaag ttagcagatt cctataccat aaagaaaact gtaagcacag atacttcaaa
    12661 tcctgttatt acaaataatc aaaatgttga accaactgtt aagcatatac caacaaatat
    12721 aagccaactt aaagaggaaa aaactactac tgaattggtt aatactactt cacaaccatt
    12781 taaacctgtt aaaaaaattc aaaatccagc tacaactact aataagaaaa acaaaaattc
    12841 tgttctacca caattagggg ttgtccctct ttatcatcag ccattattta aacttcctat
    12901 tcctaaaatt cctaagcaat tagaacgtac tataatgtta attacttttc tagttctata
    12961 tttgggattc ttaatatgtt tatggttgag ctggaaagaa ataaataaaa ggaaatagat
    13021 aaaaagtaaa tatgcgatat agcaatagga ccaattagaa aatttatgca aataatcgat
    13081 ttttgtagat tcaaaactac atttttgcat aaattagtaa attggtccta tctttatatt
    13141 taactttttt aattacacta tttttattat gcggtaactg ttattttgtt tttaaataat
    13201 caatgacatc atttaacgtc ttacaaacag caatagtttt ctctaaatat tcttttgctg
    13261 gtcttttcat atcaggtata caaataactg gaatatgtgc attataggca gccataatac
    13321 cattttcact atcttctaaa actattgctt cattagttga tacatttgtt ttttcacaag
    13381 cttttaagaa aacttctgga ttaggcttac ttagtgttac atcttcacta aatacaaatt
    13441 cgtcaaagta gctgagaata tcgtgccctt ttaaaataga aatcgctcta tctttggtac
    13501 ttgatgttgc caaagttact ttataattat tctcttttag gtacataagt agagatttta
    13561 cccctacttt taattccaca ccttgtgaaa taagtttgcg ttcaatattc aaaacttcat
    13621 ctaaacattc ctgataagat accgataagt tatatgtatc tataaaacgt ttaatatttt
    13681 ctttttctgt tttcccacta taatgttttg catattcttc tttagtaaaa ctatatccat
    13741 attcagataa taattcctga tatattttta aagatacaat ttctgtatct actagtaatc
    13801 catcaagatc aaatatagcc gctttaatca caataaatca accacctttc gtaatacata
    13861 tttattatat catataatta ttcaatctta ttttgacata aaagttgatt atcttgtcat
    13921 agacaattta atacctttac ctcaatcttc agacactatc cgatatttct tagcgaactt
    13981 ttcggctgta acaaccttag aattggtaaa atcaataaca tctccctcaa aaccaatatc
    14041 atacatcgac gcgctgccac cagctatact aacaaaagaa gctgagatac cattcaaaat
    14101 agttcgtatt attccttttt ttgctctagt aactgctggc caataaattc tgactttatt
    14161 accactacca tgtaaccatc gcaacccatt atgctcaaaa gcatctttaa cccaatcagg
    14221 ctggacatta tctctactca cttgccaaac atctactttt ctacctctat agattgcttt
    14281 catttgcttt atcacctttc ttattacttt ttcctatcct taatagccat aactaatcta
    14341 tatatcacta atactatata taccaacagt gctattaata ctattatata tagtatttta
    14401 ttctcataac cttcatcaaa tattgtagtt actattagaa atgttcctaa tattgcttgc
    14461 tttctagctc gtttatctaa ttcaccatgt tttttcttat aattaacttc caaaattgct
    14521 gatgttataa aaaatatcca aataattgtt ttaataacta aataatccat tattccacca
    14581 cctattctct attttttgcc attattatac tatcctaatt aaatttaatt ctgtattttc
    14641 ttaattaaca ctcttttctg cttatttggt taacaacata tccatgtacg ttaaaaaaat
    14701 agcgacaaaa catcgctgtc ttgccactat tcccaactat gtcaactcac cccagtctaa
    14761 agacatgggg cttgtgagtg ttcaagcctt tcggctctac taacacactc ttccgtgggt
    14821 aaaatacag
//
