LOCUS       c00116_gnlPro..        13236 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMIHIBLO_116.
ACCESSION   c00116_gnlPro..
VERSION     c00116_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 18:28:53
            Original ID  :: gnl|Prokka|LMIHIBLO_116
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13236
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13236
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3236](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(3..3236)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13236
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13236
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(3..3236)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_1"
                     /sec_met_domain="PFOR_II (E-value: 1.3e-19, bitscore: 59.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 6.7e-84, bitscore: 270.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 4.7e-32, bitscore: 100.7,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.9e-13, bitscore:
                     38.7, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 3.2e-13, bitscore: 39.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.4e-08, bitscore: 22.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.8e-05, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-26, bitscore: 81.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSCRQTGFAMLCEGSVQEVMDMAAVAHLATI
                     KSRVPFVNFFDGFRTSHEIQKIEMLENEDLAGLIDQQALAEFRQRALNPNNPVARGMAE
                     NPDHFFQHRESCNNFYEAVPAIVEEYMNEISKITGRPHGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLMSKGEKVGLVSVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGTENAPVIVGGRYGLGSKDTTPAQIIAVFKNLALPMPKNHFTVGIVDD
                     VTFTSLPQEEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNITVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLAVDPAWANLEVEAPAANNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWEQGTAQYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGANFETLKAVGKQFDGMTFRIQVDVLDCLGCGNCADV
                     CPGNPKKGGKALTMKHLESQLSQAANWEYCAKNVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTKNEKGQGPAWANS
                     LFEDFCEFGLGMTLADKKLRARIEAAMKDAIASDTCPAEYKEAFQEWIDGKDDADKSKA
                     AAEKIIPMVEAAKDKCKNCAIIAEFKNYLVKKSQWIIGGDGASYDIGYGGLDHVIASGE
                     DVNILVLDTEVYSNTGGQSSKATPLGAIAKFAASGKRVRKKDLGMIATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLVIAYAPC"
     CDS             complement(3279..4457)
                     /locus_tag="ctg116_2"
                     /transl_table=11
                     /translation="METFYRTHSYLVEHTNAPVRRDLMDEIDWNDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGTDHSCLFINMNNFYFSKYTLVEFAAEFVKRGGKVLLIDQVFKYPEWS
                     HDLRACYEMFPTLKIIFTGSSVMRLKEENPELSGIVKVYYLRGFSFREYLNLQSGNCFR
                     AYTLQEILENHEQIAKTILRNVKPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMIE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPVAPNVSQLATEIQTSRATVMNYIKYLADAR
                     LINMVYPKGEEFPKKPSKLMMHNTNLMYSIYPVKVEEQDVLDTFFMNTLYKDHKLYKGD
                     KGTSFMVDNGLHFRICAEGCKFKNNPNVYYALHKLELGHGNMIPLWLFGFLY"
     CDS             4561..5772
                     /locus_tag="ctg116_3"
                     /transl_table=11
                     /translation="MVCTLKHLSLCPEMEALYLFNPENDMALACGDPYYMAPASARRMA
                     AELSMLPAWYAEEGGTVWLDSAQRMKTMERQSFLPLSVNWVLEFVPIYNKVIPWGWNPS
                     LVRRLQEAGFPDTAYPSVERMKRIRQISGRQTAVKVLRRLCRHIGGNIPILGEAFVLSS
                     IEEVKAFVLSHSRALLKAPWSGSGRGIQYVSGSFPIPLEGWIRHILTTQHEVIGEPFYD
                     KLLDFAMEFFADEWGQVHFIGYSLFETDKRGVYKENLLAADRVIEARISTYVSAEILHQ
                     VGRALQVELAEVIKGSYEGYLGVDMMVCRTQNSGYAIHPCVEINLRMNMGVVARLIYDN
                     YVCDGVQGRYVIEYYAKPGEAWHSHLALQEKYPLYLENGKVKSGYLSLTPVENNTSYQA
                     YILI"
     CDS             complement(5811..7184)
                     /locus_tag="ctg116_4"
                     /transl_table=11
                     /translation="MMKHTLLYIAVSGMTLLTSCQLGKHYTRPDLHLPQQLDTLRQQDT
                     LSIADMQWWEIYTDTTLQSLIEKTLDNNKDMKIAAARVKELAAMKRIDFANLFPQLNGG
                     AYAQKEGSNYGGNNYKNDPELGGKLTVTWELDLWGNLRWAKDKSIAQFLGSIEAQRALK
                     MSIVSEVAQAYFELVALDNELNIVRQTLYARKEGVRLAKLRFEGGLTSETSYQQAQVEY
                     ARTATLVPELERKISLKENDIAFLAGEYPHRIQRSILPEEVKLPETLPVGLPSTLLERR
                     PDVREAEQKLIAANASVGIAYTNMFPRLSLTAQYGVESEEFSDFFKSPIHYISGNLLTP
                     LFAMGKYRATLKAKKAAYEQECYSYEKSVLTAFKEARNAIVDFNKIKDIYESRLQLERS
                     SKATMELAQLQYINGVIGYLDVLDAQRSYFDAQIGLSNAIRDKQITLVKLYKALGGGW"
     CDS             complement(7206..10307)
                     /gene_functions="resistance (resist) RND_efflux (Score:
                     984.9; E-value: 3.4e-298)"
                     /gene_kind="resistance"
                     /locus_tag="ctg116_5"
                     /transl_table=11
                     /translation="MKVSFFIDRPVFSAVISILIVIVGIIGLTMLPIDQYPQITPPVVK
                     ISASYPGASALTVSQAVATPIEQELNGTPGMLYMESNSSNSGGFSATVTFDISADPDLA
                     AVEIQNRIKLAESRLPAEVIQNGISVEKQAASQLLTLCLTSTDPKFDEIYLSNFATLNV
                     LDLIRRIPGVGRVSNIGSRYYAMQIWVQPDKLANFGLTVADLQNALKDQNRESAAGVLG
                     QQPVQGLDVTIPITTQGRLSTVSQFEEIVVRANADGSIIRLRDVARISLEAQSYNTESA
                     INKENAAVLAIYMLPGANAMEVAKSVKEAMEEISKNFPEGMSYEIPFDMTTYISESIHE
                     VYKTLFEALILVIIVVYLSLQSWRATVIPLVAVPISLIGTFGFMLIFGFSLNILTLLGL
                     VLAIGIVVDDAIVVVENVERIMEEEKLSPYQATKKAMEGLTGAIIATSLVLAAVFVPVS
                     FLGGITGQLYRQFTVTIVVSVLLSTVVALTLSPVMCSLILKPEDPNKKKNIIFRRINKW
                     LAIGNHKYVGLIKHIVKHPRRVLSTFGMVLIAILLIHRIIPTSFLPIEDQGYFKIELEL
                     PEGATLERTRIVTERAVEYLMENPAVEYVQSVAGSSPRVGTSQARSELTIILKPWEERD
                     SQTIDDIMAQVKKDMSQYPECKVYLSTPPVIPGLGSSGGFEMQLEARGDATFENLVQAT
                     DTLMYYASKRKELSGLSSALQADIPQLYFDVDRDKVKFAGVPLADVFSTMKAYTGSVYV
                     NDFNMFNRIYRVYIQAEAPYREHKENINLFFVRGTDNAMIPLTSLGTTSYTTGPGSIKR
                     FNMFNSSVIRGEAADGYSSGQAMEIIEQIAREHLPENIGVEWSGLSFQEKQAGGQTGMV
                     LALVFMFVFLFLAALYESWMVPVAVLLSLPVAALGAYLGVWGCGLENDVYFQIGLVMLV
                     GLAAKNAILIVEFAKEQVDRGIDVVQAALHASQLRFRPILMTSLAFILGMLPMVIASGP
                     GSASRQAIGTGVFFGMIFAVTVGILLVPFFFVLIYKMKAKMKQK"
     CDS             complement(10374..11573)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg116_6"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 3.7e-09,
                     bitscore: 25.7, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFFTHKEIALKKKRTALVVIGIGLVIGIYLIVSHQPAKMPELP
                     VVAIAPATQDDVEIYGEYVGRVRAQQFVEVRARVEGYLEQMLFAEGTYVTKNQVLFVIN
                     QDQYRAKADKARAQLKKDEAQAQKAKRDLERIRPLYEQNAASQLDLDNATAAYETAEAS
                     VAMSSADLDQAELELGYTIVRSPLAGHISERHVDLGTLVGPGGKSLLATIVKSDTVLVD
                     FSMTALDYLKSKERNVNLGQKDSTRSWQPNVSITLADNTIYPYKGLVDFAEPQVDPRTG
                     TFSVRAEMPNPERVLLPGQFTKVKLLLDVRESATVVPLKSVIIEKGGAYIYVMRKDSTV
                     ERRFIELGPEFQNQVVVERGLAPGEDIVIEGYHKLNPGMKVKVSPAVEDKKTEEEDTIG
                     "
ORIGIN
        1 atacacggag cgtaagcgat aaccaatgac ggaccgggat aagcttctgc ttcacggata
       61 gctttcaaag tctgagcttg gtcagcaccc atagcaatct gggcaacata tacataaccg
      121 taagtagtag cgatcatacc aaggtctttc ttacgtacac gcttacctga agcggcaaac
      181 ttagcgatag cacccagcgg agtagcctta gatgactgac caccagtatt agagtaaact
      241 tcagtatcca ataccaaaat atttacatct tcgccggaag caatcacatg gtccaaacca
      301 ccgtaaccga tatcgtaaga agcaccgtca ccaccgataa tccattggct cttcttaacc
      361 aaataattct tgaattctgc aatgatagcg cagttcttac atttatcttt agcagcttcc
      421 accattggaa tgatcttttc ggcagcggct ttgctcttgt ctgcatcgtc cttaccatca
      481 atccattcct ggaatgcttc tttgtattct gctggacaag tatcactggc gatagcatcc
      541 ttcatagcag cttcgatacg tgcacgaagt ttcttgtcag ccaaagtcat acccaaaccg
      601 aattcgcaga aatcttcgaa caatgagtta gcccaagcag gaccttgacc cttttcgttc
      661 ttagtataag gagttgaagg aacagaacca gagtagatag aagaacatcc ggtagcgtta
      721 gcaaccattt cacggtcacc gaataactgg gaaatcagtt tcacatatgg agtttcacca
      781 caacctgaac aagctccaga gaattcgaac aacggagtag cgaactgaga gttcttcaca
      841 ttggctttga tatctactaa atgttgtttg ctcttcacgt tcttagcgca gtattcccaa
      901 ttggctgctt gagacaactg gctttccaaa tgtttcattg taagagcctt gcctcccttc
      961 ttcggattgc ccggacaaac atcagcacag ttaccacaac ccagacagtc aagcacgtca
     1021 acctggatac ggaatgtcat tccgtcaaat tgtttaccta cagctttcaa tgtctcgaag
     1081 tttgcaccct tttgttcttc agcgtcaagt acgaacggac ggatagaagc atgaggacaa
     1141 acatatgcac acttgttaca ctggatacag ttttcagcat tccattcagg tacgaatgca
     1201 gctacaccac gtttttcgta ttgagcagta ccttgttccc aagtaccgtc ttcgatgcct
     1261 ttgaatgcag ataccggcaa caagtcacca tcctgagcgt tgataggacg aactacttcg
     1321 ttgatgaatg cagggtcatt gttagcagca ggagcttcaa cttccagatt agcccaagcc
     1381 ggatcaacag ccaattgttt gtattcgcca ccacggtcta cggcagcata gttcttgttc
     1441 accacgtctt cgcccttctt gccataagac ttaacgatga atttcttcat ctgttctaca
     1501 gccaagtcaa caggaataac gcctgtgata cggaagaatg ctgattgcag gatggtattg
     1561 gtacggttgc ccaaaccgat ttcctgagca atctgagttg cattgatata gtaaacagta
     1621 atgttgtttt gtgcgaaata tttcttaacc ttgttcggta agttcttggc cagttcttca
     1681 ccttcccaaa tagtgttcaa caagaaagaa ccgttcttac gtaaaccacg agttacatcg
     1741 tacatgtgca aataagcttg tacgtggcaa gctacgaagt tcggagtatt tactaaataa
     1801 gtagaacgga taggagtatc gccgaaacgg aggtgagagc aagtgaaacc accagatttc
     1861 ttagagtcgt atgagaaata agcctgacag tgcttgtcgg tgttgtcacc gataattttc
     1921 actgagttct tgttagcacc tacagtaccg tcagcaccta atccgtagaa tttagcttca
     1981 aacatacctt cgccgcctaa tgcgatttct tcttcttgag gaagagaagt gaaagttaca
     2041 tcgtctacga tacccacagt gaagtggttt ttcggcattg gcagagccaa attcttgaat
     2101 acagcgatga tttgagcagg agtagtgtct ttagaaccta aaccgtaacg tccacctacg
     2161 ataaccggag cgttttctgt tccatagaag cagtctttaa catccagata caaaggttcg
     2221 ccgtttgctc ccggttcttt agtacggtca agaactgcga tagtcttggc agtcttaggt
     2281 acagcagcca agaaatgttt agcagagaac ggacggtata aatgtacaga aaccaaacct
     2341 actttttcac ctttgctcat caagtagtcg atagcttcgc gggcagcttc tgtaacagaa
     2401 cccattgcga taattacgcg ttcagcgtct tcagcaccat agtaatcgaa caaaccatga
     2461 gggcggcctg tgattttgct gatttcgttc atgtattctt ctacgatagc cggaactgct
     2521 tcatagaagt tattgcaaga ttctctgtgc tggaagaagt ggtcggggtt ttcagccata
     2581 ccgcgtgcaa cagggttgtt aggattcaac gcgcgttgac ggaattctgc caaagcctgt
     2641 tgatcaatca gacctgccag atcttcattc tccagcattt caattttttg gatttcgtga
     2701 gaagtacgga aaccatcgaa gaagttgacg aatggcacgc gagatttgat agtagcaaga
     2761 tgagctacag cagccatatc cataacttct tgtacagaac cttcgcacaa catggcgaaa
     2821 cctgtttggc ggcaagacat gacgtcctga tggtcaccaa agatacacaa tgcgtgtgaa
     2881 gccaatgtac gagccgatac gtggaatacg caaggcagga attcaccggc aattttgtac
     2941 atgttaggga tcatcagcaa cagaccctga gatgcagtgt aagtggtagt caacgcacct
     3001 gcctgaagag aaccatgaac agcacctgct gcaccgcctt ctgactgcat ttcttgtacc
     3061 aaaactgttt cgccgaagat gtttttacga cctgcggcag cccattcgtc tacgtattca
     3121 gccatagtag acgacggagt gatgggatag atagcagcta cttcagagaa catatacgag
     3181 atatgtgctg ctgcctggtt accatcacaa gtgatgaatt ttttttgttt agtcatacaa
     3241 ttactaatta ttaggtaata aaatctattc tctatctctt aatataaaaa gccgaaaagc
     3301 cataatggga tcatatttcc gtgtcctaat tccaatttgt gtagggcata atacacgttt
     3361 ggattatttt tgaacttgca cccttctgcg caaatacgga aatgcagtcc gttgtctacc
     3421 ataaatgaag tgcctttatc gcctttatat agtttatggt ccttatacag ggtattcatg
     3481 aaaaatgtat ccagtacatc ctgttcttcg acctttaccg gataaatgga gtacatcagg
     3541 ttggtgttgt gcatcatcag tttggaaggt ttcttgggaa attcctctcc cttgggataa
     3601 accatattga taagacgcgc atctgccaga tacttaatgt aattcatcac cgtggcacgt
     3661 gaagtttgaa tctccgtggc cagctggctg acgttcggag caacgggtcc gtccacagct
     3721 agcaaatata gtaatttttt tatctttgaa agatatttca gctcaatttg tttgataaga
     3781 agtatatcta cttctatcat catattcatg gtttttagca gattctccga aaagttacgt
     3841 ttttccagga agaatgggta gaaaccgtga tgcagatagt cttgaaaata atccaagggc
     3901 ttcacgttgc gcaggatggt tttcgctatc tgttcgtgat tctccaaaat ttcttgtaag
     3961 gtataggcac ggaaacaatt gccgctttgc aaattcagat attcgcggaa tgagaaacct
     4021 ctcagatagt ataccttgac aatgccgctc agttctggat tttcttcttt cagtcgcatc
     4081 acagatgatc cggtgaatat aatcttcaga gtaggaaaca tttcatagca agcacgcagg
     4141 tcgtggctcc attcgggata cttaaacact tggtctatca acaaaacttt tcctcctcgt
     4201 tttacgaatt ctgcggcaaa ctccactaat gtatatttag agaagtaaaa gttattcatg
     4261 ttgatgaaca gacatgagtg atccgttccg aacttttctt ttgcatattg caggaggaaa
     4321 gtcgttttcc ctacgccacg agtacccttg ataccgatca gtctgtcatt ccagtctatc
     4381 tcgtccatca agtcccggcg aacaggagca tttgtatgtt ccaccagata actgtgtgtt
     4441 ctgtaaaagg tttccatggt tgctttttta tcggctgcaa atatagcaat actaattcaa
     4501 attgcaaact ggagatagca aaatattatt tttttttcta ctaaaagacg gacaagagaa
     4561 atggtttgta ctctaaaaca tttatctttg tgtccggaaa tggaagcgct ttatttattc
     4621 aatccggaaa atgatatggc attagcttgt ggtgatcctt attatatggc acctgccagt
     4681 gcacgacgaa tggcggccga gctatccatg ttgcctgcat ggtatgcaga agagggagga
     4741 actgtgtggc tggattctgc tcagcgtatg aaaacaatgg aaagacaatc ttttttgccg
     4801 ctttcggtca attgggtttt agaattcgta cccatttata ataaggtgat tccttgggga
     4861 tggaatccgt ctttggtgcg tcgtttgcag gaagctggat ttcctgatac agcatatcct
     4921 tcagtagagc gtatgaagcg tatccgtcaa atatccggac gtcagacggc tgtaaaagtg
     4981 ttacgccgcc tttgtagaca tataggtggg aatattccca tattggggga ggcttttgta
     5041 ttgtcgtcaa tagaggaagt gaaggctttt gtgttgtctc attctcgtgc tttgttaaaa
     5101 gcgccatggt ctggtagtgg aagagggata caatatgttt caggtagttt tcccatccct
     5161 ctggaagggt ggattcgaca catacttacc actcagcatg aggtgatagg agaacctttt
     5221 tatgataagc ttttggattt tgccatggag ttttttgcag acgagtgggg acaggtacat
     5281 tttatagggt attccttatt tgaaacggat aagagaggtg tttataaaga aaacttgttg
     5341 gcggcggatc gggttattga agcgaggata tccacttatg tttctgcgga aatcttacat
     5401 caggttggga gggcgttaca ggtagagttg gcagaggtga taaaagggag ttacgaaggc
     5461 tatctggggg tggatatgat ggtatgccgt acccaaaata gcgggtatgc cattcatccg
     5521 tgtgtggaaa taaatcttcg tatgaatatg ggagtggtag cacgcttgat atatgataac
     5581 tatgtgtgtg atggcgtgca gggacgatat gttatagaat attatgcaaa gcctggtgag
     5641 gcatggcatt ctcatcttgc gcttcaagaa aagtatcctt tatatctgga gaatggaaaa
     5701 gtgaagtcgg gttatttgtc acttacaccg gtagagaaca atacgtccta tcaggcatat
     5761 atcttaattt gattttccgg ataaaggaag atacagaaaa gaggggatgg ttaccatcca
     5821 ccccctaatg ctttatacaa ttttactaat gtaatctgtt tgtctcttat tgcattgctt
     5881 aatcctattt gtgcgtcgaa atagctacgt tgtgcatcca atacatctag atagcctatt
     5941 actccattga tgtattgcaa ttgggccagt tccattgttg ctttagagga acgttccagt
     6001 tgcaggcgcg attcgtagat atcttttatc ttattgaagt ccacaatggc attgcgggcc
     6061 tctttgaatg cagtcagtac tgatttttca tagctgtagc attcctgttc gtatgcggct
     6121 tttttggcct ttagggttgc tctgtatttt cccatggcga agagaggagt tagaagattg
     6181 ccactgatat aatgaatggg cgatttgaag aaatcagaga attcttcact ttctacgcca
     6241 tattgtgctg tgaggctaag tcgtgggaac atattggtat aggcaatacc tacactggca
     6301 ttggctgcta ttaatttctg ttctgcttca cgtacatcgg gacgacgttc cagcagagtg
     6361 gagggtagac ctactggtaa tgtttcaggt agttttactt cttcgggtag aatggaacgc
     6421 tgtatgcggt gcgggtattc gcctgctaaa aatgcaatat cattttcttt caatgaaatt
     6481 ttcctttcta gttcaggaac taaagttgcg gtacgtgcat actccacttg tgcctgttga
     6541 taagaagttt ctgaagttag tcctccttca aaacgaagtt ttgccaagcg tactccttct
     6601 ttacgggcat agagtgtttg acgaacaatg ttcagctcat tgtctaatgc gaccaattca
     6661 aaataggctt gtgccacttc ggacacaata ctcattttca aggcacgttg cgcctcgatg
     6721 cttcccagga attgtgctat gcttttgtct tttgcccaac gcaggttacc ccataggtct
     6781 aattcccaag ttacggtaag tttaccaccc agttcggggt catttttata gttgttacca
     6841 ccataattac ttccttcttt ttgagcataa gcgcctccgt tcagttgggg gaaaaggttg
     6901 gcaaagtcta tgcgcttcat tgcggcaagt tcttttacac gtgccgcagc aattttcatg
     6961 tctttgttgt tatccaacgt tttttctatc aagctttgca aggttgtgtc cgtatagatt
     7021 tcccaccact gcatatcggc aatagataat gtatcctgtt gtcgtaacgt atctaattgt
     7081 tggggcagat gcaagtcggg acgtgtgtag tgcttaccta attggcaaga agtcagcaaa
     7141 gtcattcctg atacggctat atataataat gtatgtttca tcatttcttt cgtcttttta
     7201 tatccttatt tttgtttcat tttcgctttc atcttgtata tcagtacaaa gaagaaaggt
     7261 actaacaaaa ttcccacagt tacagcaaag atcattccga agaatacacc tgtaccaata
     7321 gcttgacggc tggctgaacc tggcccgctg gcgataacca taggtaacat acctaagatg
     7381 aatgccaatg aagtcatcaa aataggtcga aagcggagtt gtgaagcatg gagtgcagct
     7441 tgtaccacat ctattcctct gtccacttgt tctttggcaa actctacaat aagaattgca
     7501 tttttggcgg ccagtcctac caacatcacc aatccgatct ggaaatagac atcattctcc
     7561 aatccacagc cccatacacc tagataggca cctaatgcgg ctacaggtaa agagagtaat
     7621 actgcaaccg gtaccatcca gctttcgtat aaggcagcaa ggaacaaaaa cacgaacatg
     7681 aacactaatg ccagcaccat accggtctgt ccacctgctt gtttttcctg gaaagatagt
     7741 ccgctccatt ctacaccgat attttctggt aggtgttcgc gagctatttg ttcgataatt
     7801 tccatggcct gtcctgaact gtaaccatct gcggcctcac cgcgaatcac agaactgttg
     7861 aacatattaa aacgtttgat gctgcccgga cctgtggtat acgaagtggt acccaacgag
     7921 gtgagcggta tcatggcatt gtctgtaccc cgtacaaaaa ataggttgat attctcctta
     7981 tgttcccggt agggtgcttc tgcttgaata tatacacggt agatacgatt aaacatattg
     8041 aaatcgttta catataccga acctgtataa gctttcatgg tcgagaatac atctgctaaa
     8101 ggtactcctg cgaattttac tttgtcacgg tctacatcga aataaagttg ggggatgtcc
     8161 gcttgtaaag ccgaggataa acctgataat tccttacgtt ttgatgcata atacatcaat
     8221 gtatccgtag cttgtaccaa attttcaaaa gtggcatctc cacgtgcttc cagttgcatc
     8281 tcgaaaccac ccgaactgcc caatcccgga ataacgggag gggtggaaag atataccttg
     8341 cattcggggt attgcgacat gtcttttttt acctgtgcca taatatcgtc aatagtttgc
     8401 gagtcacgtt cctcccaagg ttttaagatg atagtcagtt cacttcgtgc ctgactggtc
     8461 cctacacgcg gactgcttcc tgccacgctt tgtacatatt ccactgccgg attttccatc
     8521 aggtattcca cagcacgttc cgtcacgata cgtgtacgtt ccaacgttgc accttcgggc
     8581 agttccaact ctattttaaa atatccttgg tcttcgatgg ggaggaagct ggtgggaata
     8641 atgcgatgga ttaacaggat ggcgatcaat accatgccga atgtgctcag tacccgacgc
     8701 gggtgtttca caatgtgctt gatgagtcct acatatttat gattgccgat agccagccac
     8761 ttattgatac ggcggaatat gatattcttt ttcttgttcg gatcttccgg tttcagaata
     8821 agtgaacaca tgactggact cagtgtcaaa gctactaccg tagacagtaa tacagatact
     8881 acgatggtta ccgtaaactg gcgataaagt tgtccggtaa ttccacctag aaaacttacg
     8941 ggaacaaata ctgctgccag taccaaagaa gtggcgataa tggctcctgt aagtccttcc
     9001 atagctttct tggtagcttg gtagggagat agtttctcct cttccatgat acgctccaca
     9061 ttctctacta ccacgatagc atcgtccacc acaataccga tggcaagtac caatcccaac
     9121 agggtcagga tattaagcga gaatccgaaa atcaacataa atccaaaagt tccaatcagt
     9181 gagataggta cggcaactag tgggataact gttgcacgcc agctttggag tgaaaggtat
     9241 actacgatga taaccagtat cagggcttca aacagtgttt tgtacacttc atgaatggat
     9301 tccgaaatat acgtagtcat atcgaaaggt atctcgtaac tcattccttc gggaaaattc
     9361 ttgctgattt cctccatagc ttctttcacg ctttttgcta cttccatagc gttggctcct
     9421 ggtaacatat agatggccaa taccgctgca ttttctttgt tgatggcact ctcggtattg
     9481 tatgattgtg cttcgagtga gatgcgggcc acatcacgta aacggatgat ggaaccatcg
     9541 gcattagcac ggactacgat ttcctcaaac tggcttacgg tagatagacg tccctgagta
     9601 gtgatgggaa tggttacgtc taatccttgt acgggttgtt gtcccagtac accggctgct
     9661 gattctcgat tttggtcttt tagtgcattc tgcaagtcgg ctacagtcag accgaaattg
     9721 gccagtttgt cgggttgtac ccagatttgc atggcataat atcggcttcc gatgtttgaa
     9781 acacgtccta cgccagggat acggcggatt aggtccagca cattcagagt ggcaaagttg
     9841 ctaaggtata tttcatcgaa cttcgggtcg gtagaggtaa ggcatagggt cagcaattga
     9901 ctggcagcct gtttctctac cgaaatacca ttttgtataa cttctgctgg gaggcgtgat
     9961 tctgctaact tgatacggtt ctgtatttcc actgccgcta gatcgggatc tgccgagata
    10021 tcaaaagtga cggtggctga aaaacctccc gaattggaac tatttgattc catgtaaagc
    10081 attcctgggg taccgttcaa ttcctgctct ataggagtgg ctacagcctg tgatactgtc
    10141 agggcactgg cacccggata ggatgcgctg attttcacta ccggcggagt aatctgcgga
    10201 tattggtcaa tgggtagcat cgtgagaccg atgataccga caatgactat taatatggag
    10261 atgacagctg aaaataccgg tctgtctata aagaaactaa ctttcataat gtctattgtt
    10321 tttttgaatg cgtaaatttt cctccatagg ggaattcgta ttcgggagtg aaattatccg
    10381 atcgtatctt cttcctccgt ttttttgtcc tctacggcag gacttacttt cactttcatg
    10441 cctggattca gcttgtggta tccttctatg acaatgtctt ctccgggggc caagcctctt
    10501 tccaccacta cttgattttg gaattcagga cctaattcaa tgaaacgtct ctctactgta
    10561 gaatctttgc gcattacata aatataggcg ccgccttttt ctatgataac ggactttaac
    10621 gggactaccg tagcactctc tctgacatcc aataatagtt ttactttggt gaactgccca
    10681 ggaagtaata cccgttctgg attcggcatt tcggcacgta cggagaatgt acctgtgcgt
    10741 ggatcaactt gcggttcggc aaagtctact agtcctttgt atggataaat agtattatct
    10801 gccaaagtaa tggatacatt gggttgccag gagcgggtgg agtctttttg acctaagttc
    10861 acattacgtt ctttactttt cagatagtct agagcagtca tgctgaaatc cactaataca
    10921 gtatcacttt ttactatggt agcaagcaat gatttgccac ccggaccgac taatgttcct
    10981 aaatctacgt gacgttcact gatatgccct gctaatggag aacgaactat agtataacct
    11041 agttccagtt ctgcttgatc aagatcggca ctactcatag ctaccgacgc ttctgctgtt
    11101 tcatatgcag cagtagcatt gtccaagtcc aactggctgg cagcgttttg ttcatatagc
    11161 ggacggatac gttctaagtc gcgttttgct ttttgtgctt gtgcctcatc ctttttcaat
    11221 tgggcgcgcg ctttgtcagc tttggcccga tattgatctt gattgataac aaacagcact
    11281 tgatttttag tgacatatgt accttctgcg aaaagcattt gttctaaata tccctctact
    11341 cgggcacgta cttcaacgaa ttgctgtgca cgtacgcgtc ctacatattc accatatatt
    11401 tccacatcgt cttgcgttgc tggtgctatg gcaactactg gaagttccgg catctttgcc
    11461 ggttgatggg aaacaatcag gtaaatcccg ataactagtc caatacctat tactacaagc
    11521 gctgttcttt tcttttttag cgcaatttct ttgtgtgtaa aaaatagttt catactttag
    11581 ttttgttatt gtttaagatg ccatcagtag aaatacaagc agcgtgccaa actattgtaa
    11641 atagtctttc ctattcataa tcagtgcttt atttctgtct tttgttgata gggaaagtgt
    11701 ggaaaatagg caacagctgt agaataattc cacagtaggc gtaattaaat ttagtagagg
    11761 attatcgatt tggatgcaaa aatagtaaaa tagtgggtaa tcttaaaata tttattcact
    11821 attcattata atgaggaaga tgttatagtg ttagcagata tgtatgcaat ttaaattttg
    11881 cttgagatcg tcgtatctgc aaccttattg ttttgaaaac acgccccctt tcattttgaa
    11941 aagggttgtg tttttctttt ttatgactga atatggtatc tgtttgttta tcaggagatt
    12001 atagtcttct ttttcatttt ggcatagtat tcgctatata cttgtcaaat ataaaaggta
    12061 taaaaagatg ggagaatttt ataatccaga taaattatat aaaggtggaa gccgaaataa
    12121 tagcttgata aataaaaaaa tgatattccg tgtattggga gtattacttt ttattgaatc
    12181 tgctatgttt ctgctttgtg cggctatttc cttatgttac ggcgagcaag attatcaata
    12241 ttttctatat accattcttt tgaatacatt ggtcggtgga gttttgctaa tttgtagtag
    12301 aggtgctgag aatcgactaa cacgacgaga tgggtactgt attgtaactt ttacttggtt
    12361 tttgtttacg ttgtttggaa tgctaccttt ttattttagt ggaggaatcc cttcagtgac
    12421 agatgctttt tttgaaacca tgtcgggttt tactactaca ggagctacta tattagatga
    12481 tatagaatct ctttcacatg gcctgttatt ttggcgtagc ctgacacaat ggataggtgg
    12541 cttgggtatt gtttttttta ctattgctgt gcttcctatt ttcgggggag gaactataca
    12601 acttttttca gctgaggcta tcggagtgac gcacgacaaa acacatcctc ggattgatgt
    12661 gatggctaag tggctgtgga tgatatatgc tatccttaca gttgtagaaa ctatgctgct
    12721 gatgatagga ggaatgagtt tttttgacgc ggtatgtcat tcattctcta caacggctac
    12781 aggtggttat tctactaaac aagccagtgt ggcttattgg aattctccgt ttatagaata
    12841 tgtaatagcg atatttatga ttctttcggg tattaatttc tctctctatt ttatgtgcct
    12901 gaaagggaag ggcaagcgtc tatttcagga tgatgaattc cgttggttta tgaaatcagt
    12961 aagtattctg acgcttgtta tcacgcttgc cttagttttt cagaatcatt atgattggga
    13021 aaaggcattc cgcagggctc tgttccaagt ggctacggca catacgtcat gcggttttgc
    13081 aacggatgat tataacttgt ggccatcttt tacatggatg cttcttattt ttgctatgtt
    13141 gtcgggtgga tgtacggggt ctactagtgg gggaatcaaa aacatgcgcc ttatgattct
    13201 ggcgcgtaat atcaagaatg aattcaaacg gatgct
//
