LOCUS       c00074_gnlPro..        15726 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBLBNPPP_74.
ACCESSION   c00074_gnlPro..
VERSION     c00074_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 18:37:12
            Original ID  :: gnl|Prokka|CBLBNPPP_74
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15726
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15726
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3041:5726]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3042..5726
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15726
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15726
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(108..887)
                     /locus_tag="ctg74_1"
                     /transl_table=11
                     /translation="LEGEFIGQSTHEYSVIYMRHIGKDRFAAISFPFQPFNGGGFGLGL
                     FSRKGDTIAIKNDFYSFLLPHEKSGFTTSIAPAYSDAQNSVLFKTGSNYTVFSISADRI
                     SAACVLDLKNSDAEVIRSLDVTDMSNLRIEKKAPKDIFVQDMIEFPEHYYFRLLYNQGY
                     YIASVDKKTGKTLVEKCEMPGSIYELADANLQHGMQGTRSYRNFPVWGRVIKDELVQVV
                     TPYELNLYKSLRSITIPQELDLKGEEGNPVFVFYSLI"
     CDS             complement(1441..2880)
                     /locus_tag="ctg74_2"
                     /transl_table=11
                     /translation="MRKEKVFLMNNLYTFAYMRKDLNGPRHFSIGIKFTILLFTIAILV
                     LVLFSYRSDKHGNLFWQVEKLIPHHPDSALVLLEKVTDINGLSLREKARYCLLWTESRD
                     EAGLRHTSDSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPSLALECYLRALEYE
                     GGNWDYEFWGRLYNQIGRLYAEQELYGKAMSFLRKASAQYQLLNDTAGQGRILEEVKKY
                     EALRDSIGSLSARESIYQITSRYDVRPVREDLYRKELMLSQRGQERYLYAFIIGIILFI
                     CFLLYRRWRNTQENALRREEALRRSIASQQQRMREEKEENERQIALLEKRITKIKEEKD
                     QELMLVSLQLEKQRLEICNESIHNKESKHLLSVAILRKSEVYEKFHDRDAGKIVFEDWE
                     LLEVLLNKAYDDFTLRLKKLYPAISDTELKVCMLTKIGVPANQITRVLKYNSSVLRPRL
                     FRKIFKKEGSTETFVEFISSF"
     CDS             3042..3734
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_3"
                     /sec_met_domain="SucD_FumR (E-value: 7e-74, bitscore:
                     238.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAM
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             3783..5726
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 197.2; E-value:
                     1.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 7.7e-61, bitscore:
                     197.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2e-38, bitscore:
                     122.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVHGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFNEAEKNIQARINKLMSIKGKESVDSIHKRLGHI
                     MWEHIGMARNAESLKEAIQMLKDLKKEFWSNVFIPGNADDLNVELEKALRLADFIEIGT
                     LMAHDALDRAESCGGHFREEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             complement(5727..5891)
                     /locus_tag="ctg74_5"
                     /transl_table=11
                     /translation="LLVQDIQHFQERSALVDVFKLVSFELSFYIRTFLTPNFECDIYIF
                     IHDSNFCND"
     CDS             6024..6506
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg74_6"
                     /sec_met_domain="Fer4 (E-value: 2.4e-07, bitscore: 21.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.4e-12, bitscore: 38.1,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.5e-06, bitscore: 18.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRFNDGETITIEPWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSV
                     NTGGVPDANAIPIPKPDAEMAMDAAACIGCGACAAACKNGSAMLFVSAKVSQLALLPQG
                     KVEAARRAKAMVAKMDELGFGNCTNTRACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             6929..8140
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg74_7"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-16, bitscore:
                     51.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKALETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQVEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITHFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIAAIGHGYKANCW
                     CTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             8225..9406
                     /locus_tag="ctg74_8"
                     /transl_table=11
                     /translation="LAIAAELERRGHEVTINLPQIFEETVKPYGFKYVLQQFDDIGGMI
                     DSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTNSEFAVASIAEYCKKPLI
                     RTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNFMVKDTINKNRAKYGLAP
                     IRNFGYHAGERSYNYLLFSQHLGNVDPDWTFEWSIGGYCFNDTFQYDEKAYEEMISFVD
                     SAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSGWAKTGITLQADKHLFLM
                     KQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLIIDQPYWSYRIHQLGLGPE
                     GVKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGIKNICDSIERFQ"
     CDS             complement(9459..9938)
                     /locus_tag="ctg74_9"
                     /transl_table=11
                     /translation="LREADLIKQLKPVSRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNHDANIRSYCYLSTV"
     CDS             complement(9949..12903)
                     /locus_tag="ctg74_10"
                     /transl_table=11
                     /translation="MISKFATPEEYTLRIDHMNVILVDTPEKLKEKQKLFFETYKEKPG
                     GIIYLGVNGWAFMRDKIREEWGDIPSLVCSETGEMAEDECYFNQRHSSDRVIPLQEAVK
                     GYNATGLVIPYYVKGSIDLVKELIPGLRRLIFISDRRYVSTWLRDEMEKHMETSFPEGK
                     VDFYTEGSCSMDSLMAVLSEKDPHRATAVMYYSWITEKPFLNHSLLYSTLYQGINGISR
                     HPVFSLYDMGVEEGYTIGGYYNSTKTIETALIPLLQQVYNGEDMGKIPVSTVDDPHKYL
                     NYVSLMSAMSNEDNFPHDAIYLNAPPSFLEKYWMPLLGFLIFFLVVVFLAWHYVYRSKQ
                     KMKEVELRLLSRYRDLFNNMPLPYIRQRLIREGTQIDVQVLDVNHAFEEKIAPKDFVVN
                     KHGKEIANLIGGSYPLLLSAVPTVLESGKSFTCEYYFEPTGLYYTVIIMPTSEENVVDA
                     FFIDITDIHNFQTHLKAMNHKLAMALEAADLLPWRYNLAEGKIIYESKVHPGDNIETAE
                     VHTHEVSLEEYFSKIHPSFRACVEKAFGDLCSGKIKKVRKEYCLEQLTPGEDRHEWEEI
                     QVMAEYDASGKPKALIGSTISITERKQLEHDLRMARDKAEESNKLKSAFLANMSHEIRT
                     PLNAIVGFSNILASTDDLEDKKEFADIIENNNSLLLQLINDILDLSKIEAGTLEFTYDY
                     VDINAVLRDLEQSVHLKNKNPDVQISFQDYLEPCVIYTDRNRLSQLMINLLNNAMKFTK
                     TGSISFGYKLRDDNTLWFYVEDTGCGIPENKRKDIFGRFVKLNTFAQGTGLGLSICEMI
                     VTQMKGTIGVDSVEGKGSKFWFTLPFQPKKELLPAGEPKPVTLDKIARNELTILIAEDN
                     SSNYRLFESILKPEYKLIHAWNGKEAVELFHQHKPQLILMDIKMPVMDGYEATAEIRKV
                     SSSVPIIAVTAYAFAQDEQRIIKSGFDAYTAKPINGKILKDKISTLLTYRIILM"
     CDS             13325..14092
                     /locus_tag="ctg74_11"
                     /transl_table=11
                     /translation="MDMKDYDIDFKEKRTNGYLIATLFIIVGILFLLRNLGMIDPSLFD
                     LLVSWPMLLVVSGIFTIFHRNPVGGMLLVGVGVYFLFPQLNWITNDFLRIYWPLGLILL
                     GLVIMLKRKDSIRTKKHKRPFNHPPFGHRKPNDEINYETDNGFVSVDTTFNSVRHIVLD
                     PVFKGADIDVSFGNVILDLKKTTLEADETIINIDSSFSGVVIYVPKGWLVRLKVDSFLA
                     GCQDMRDLTETTDMTHTLYICGDLSFSGLELRD"
     CDS             14100..14894
                     /locus_tag="ctg74_12"
                     /transl_table=11
                     /translation="MQEHPITTSILHKGLGSLLLLLAIAIQCALLTLYGDLLLSITLVD
                     SLLSIALFAVAGYYLWYVQCTLHIMQARVAFAVLVQIACIAGCSILLQIFGLEDWEEFS
                     ITIPFRFLFGLMAWIILSQWYASRERKSEAEPIVRQMEEKTAPPPTTVPEEILDRISVK
                     DGTRIHIIPIKEIFYLQACGDYVTLFTTSGQHVKEQTMKYFERSLPSPEFVRIHRSYIV
                     NTEQILRVELFGKETYQVRLKDGTYLRASSAGYKLLKERLSL"
     CDS             15033..15374
                     /locus_tag="ctg74_13"
                     /transl_table=11
                     /translation="MVLTNVSLHRGFFIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXRL"
ORIGIN
        1 attactatca atagtaaatc ggattttcta tagatagtag ccatgaatac tatagcttct
       61 atcgctagat tattacaaga agtacaaccg agtgatacac attgaagtca gataagcgaa
      121 tagaacacaa aaaccggatt gccctcctct ccttttaagt ccaactcctg cggaatcgtg
      181 attgagcgaa gcgatttata taagtttagc tcatatgggg tcactacttg taccagctca
      241 tcttttatga ccctccccca gaccgggaaa ttccgataac ttctcgtacc ctgcatgcca
      301 tgttgaaggt tcgcatccgc cagttcatag atagaacccg gcatctcaca tttttccaca
      361 agtgtctttc ccgtcttttt atctacagag gctatataat agccttggtt atacaataaa
      421 cggaaataat aatgttccgg aaactcaatc atatcttgca caaagatatc cttgggggcc
      481 tttttttcaa ttcgcaaatt actcatgtcc gtaacatcca acgaacgaat cacttccgca
      541 tccgagtttt tcagatcaag gacacaagcc gcacttattc gatccgccga gatactgaag
      601 accgtataat tgctaccggt cttaaacaac acggagtttt gcgcatcaga ataagcgggg
      661 gcgatacttg tcgtgaaccc gctcttctca tgaggtaata aaaaggaata aaaatcattc
      721 ttgatcgcta tcgtatcccc tttcctcgaa aataggccca atccgaatcc ccctccgttg
      781 aaaggctgaa aagggaatga tatggcggcg aaacgatcct ttccgatatg acgcatatag
      841 attacagaat actcatgggt ggattgtccg ataaattcac cttccaacgt atattcccaa
      901 actcgattat tactaaataa aaaaaggcgg tcattacgtt cgtccacttg gatacatggc
      961 agaataccgc taaattcacc cggcccctgc ccttctttta ccaacgtccg gataaaacgc
     1021 ccttgccgat cgaacaggac gatacggggc tcttttacgg gaagcacata gatatatcga
     1081 tctgtcacgg cataatcata aactccgtct atcaacgagg catcatccgt ggtcacctct
     1141 aaagggacaa aagtaacccc cttgatctca tcgcctaacc ccaatagacc cggtttatcc
     1201 atccctcctc ttatatccgc agttaaaaga aaggacgctt ccgttggcga agaaccgcat
     1261 gacacgaaac aagaaacgac aaaaacacta tttaaataaa acaagataga ggctaacttt
     1321 acacttttca taaccatgct tttttgcctc caaaaatatc ccgcatatct cacaaatcac
     1381 atgataaatg agaacaaaaa tgagaacaaa cctgccaata ccgctataaa tacataataa
     1441 tcaaaaactt gagataaact ccacaaatgt ctccgtagaa ccttctttct taaaaatctt
     1501 ccggaataga cgaggacgaa gtaccgaact attatatttc aatacccgtg tgatctggtt
     1561 ggcgggaacg ccgatcttcg taagcataca gaccttcaac tccgtatcgg aaatagcagg
     1621 atatagtttt ttcagccgta aggtaaagtc atcataagcc ttattcaaca gcacctccaa
     1681 aagctcccaa tcctcaaaga caatcttgcc ggcatcccga tcgtgaaact tctcatagac
     1741 ctccgatttc cgcaagatcg caacagataa taaatgctta ctctccttat tatgaatcga
     1801 ctcgttacaa atctccagtc gttgtttctc caattgtaag gaaaccaaca tcaactcttg
     1861 atccttttct tcctttattt tcgtaattct cttttccaaa agggcgattt gccgttcatt
     1921 ctcttctttt tcttctcgca tacgttgttg ctggctagca atcgagcgtc gcaaggcttc
     1981 ttcccttcga agagcgtttt cctgcgtatt tctccatcgc cgataaagga ggaagcaaat
     2041 aaatagaatt atgccgataa taaacgcgta cagataacgc tcctgtcccc tttgcgatag
     2101 catcaattct ttcctataca agtcctcacg aaccggcctt acatcatacc gggaagtgat
     2161 ctgataaatc gattctctcg ctgacagcga tccgatagaa tcccgtaacg cctcgtattt
     2221 cttgacttcc tccagtatcc ggccttgtcc ggccgtatca ttcaagagct gatattgggc
     2281 actcgctttt ctcaaaaaag acatggcctt gccatataat tcctgctcgg cgtacagcct
     2341 ccctatctgg ttatataacc gtccccaaaa ttcgtaatcc caattccctc cctcatattc
     2401 caacgcacgt aaatagcatt ccaaagctag ggacggttga tccatatcct catagacttt
     2461 cccccggtaa aaccacgctt tgggaggcca gtaacagcct cgtgtcgtcc tataataatc
     2521 cgtagcgata gagattatgg aatccgatgt atgcctcaat cccgcctcat cccgtgattc
     2581 ggtccataac agacaataac gggctttctc tcgaagcgat aatccattga tatccgtcac
     2641 tttctctaat aacaccaaag cgctgtccgg atgatgcgga atcaatttct ctacctgcca
     2701 gaacaggttg ccatgcttgt cgctcctata cgaaaaaagc acaagaacca agatcgcaat
     2761 cgtaaacaat aagatcgtga acttaatccc tatggaaaaa tgccgtggcc cattcaaatc
     2821 cttacgcata taggcaaatg tatataaatt attcataagg aaaacctttt ccttccgcat
     2881 tatttcatgt gtcggggcac atgtcctgac ctctcctatt aatgcagaaa tatttcttta
     2941 atcgtttgcg cgatatatgg atttagcata cctttgcgtg ataattacat agtttaagta
     3001 gaaatttcta aatacaatta aataacttaa attattatct tatgtggtta cttaattctt
     3061 ctatcgggaa gaagctgata atgagtatat caggcctctt tcttgttctg ttcttattgt
     3121 tccacctgtc gatgaacgtg gcggccgttt tctccggaga ggcttataac atggtttgtt
     3181 cgctgttggg ctctaattgg tacgctgtgg cagctactct cgtattggcc gcaggcgttg
     3241 tgatccactt cgtgtacgct atcattctta ccttgcaaaa ccgtaaggca cgtggtaacg
     3301 accgttacgc tatcaacgct cgtccgaaag gcgtggaatg ggcatctcag aacatgttcg
     3361 ttttgggttt gatcgttatc ctgttcatgc tgttgcactt cagccagttc tggtataaga
     3421 tgatgttcgc cgaattgatc ggtcatcacg aagtagcatt ggggtcagct atggtatctc
     3481 cacaagacgg agccgctttt atcaactatt acttccaagg taatgccatg atcaccgttc
     3541 tttatttgat ctggtacgtg gctttgtggt tccacttgac tcacggtttc tggagcgcta
     3601 tccaaacaat cggttggaat aacacgatct ggatgaaccg ttgggaatgt atctctaaga
     3661 tcgtagctac ggttatttgc ggacttttcg cgatcattac tatcatcttc ttcctaaacg
     3721 gagtaggtgc ttaattgcaa gctacaggtt ttataattaa gaacttttga aattaaatca
     3781 ttatgtctga aataaattct aaaatacctc aaggcccgtt ggctgagaag tggactaatt
     3841 ataaaaatca ccagaaattg gtgaaccccg ctaacaagcg tcgtttggat gttatcgtag
     3901 tcggtacagg tttggccggt gcttccgctg ccgcatcttt ggcagagatg ggattcaacg
     3961 tattgaactt ctgtatccaa gattctcccc gccgtgcgca ctctatcgcc gctcaaggtg
     4021 gtatcaacgc cgctaagaac taccagaatg atggtgactc tgtttaccgt ttgttctacg
     4081 atacgatcaa aggtggtgac taccgtgctc gtgaggctaa cgtttatcgt ttggctgagg
     4141 tttctaactc aatcatcgac cagtgcgtgg ctcaaggcgt tcctttcgct cgcgaatatg
     4201 gtggtttgtt ggataaccgt tcattcggtg gcgctcaggt atcgcgtacg ttctacgccc
     4261 gtggccagac gggtcagcag cttttgttag gcgcttattc agcgttgagc cgtcagatcg
     4321 gtttgggtaa ggttaagatg tacactcgtc atgagatgtt ggatgtagtt aaggtagacg
     4381 gtcgtgctcg tggtatcatc gcccgcaact tgattacagg taagatcgag cgttacgccg
     4441 ctcacgctgt agttgtagct acgggtggtt acgttaatac gttcttcttg tcaaccaacg
     4501 ctatggcatc taacggttcc gccgcatggc aatgctacaa gaaaggcgct tacttcgcta
     4561 atccttgtat ggttcagatc cacccgactt gcgttccggt acacggtgat tatcagtcta
     4621 aattgacttt gatgtccgag tctttgcgta atgatggtcg tatctgggtt ccgaagaaac
     4681 tggaagacgc taaggcttta caggcaggaa caaagaaagg taaagatata cctgaggcag
     4741 atcgcgatta ttatttggag cgtcgttatc cggcattcgg aaacttggtt cctcgcgacg
     4801 tggcttctcg tgccgctaaa gagcgttgcg acgctggctt cggtgttaat aacacaggtt
     4861 tggctgtatt cttggacttc tccgacgcta tcaaccgtct gggtaaagag gttgtaaaac
     4921 agaaatatgg taacttgttc gatatgtacg aagaaatcac caacgacgat ccatacgaaa
     4981 ctccgatgat gatctacccg gcattgcact attcaatggg tggtctgtgg gttgattatg
     5041 aattgatgac ttctatcccg ggtctgttcg ctatcggtga ggcaaacttc tccgatcacg
     5101 gcgcaaaccg tttgggtgct tccgcattga tgcaaggttt ggccgatggt tacttcgtat
     5161 taccttatac aatccagaac tacttgtcag accagattca ggttccgcgt ttcagtaccg
     5221 atctgcctga gttcaacgag gcagagaaga atatccaagc ccgtatcaat aaattgatga
     5281 gcatcaaggg taaagagtct gttgattcta tccacaaacg tttaggacac atcatgtggg
     5341 aacacatcgg tatggctcgt aacgcagaga gcttgaaaga ggctatccag atgttgaaag
     5401 acttgaagaa ggaattctgg agcaacgtat tcattccggg taacgcagat gacttgaacg
     5461 tagagttgga gaaagcgtta cgtttggcag actttatcga gatcggtacc ttgatggcac
     5521 atgacgcttt agaccgtgct gaatcttgtg gtggtcactt ccgtgaggag caccagactg
     5581 aggaaggcga ggcattacgt cacgatgaca aattcatgta tgtctcttgc tgggaatatc
     5641 agggtgagga taaagaccct gttatgctga aggaagattt gaactatgaa ttcgtagttc
     5701 ctcagacacg taactataag aagtaatcaa tcattgcaaa aattagaatc atggataaag
     5761 atataaatat cacactcaaa gtttggcgtc agaaaggtcc gaatgtaaaa ggacaattcg
     5821 aaacttacca acttaaaaac atcaaccaag gcacttcttt cttggaaatg ttggatatcc
     5881 tgaacgagca attaatcagc gaaggtaaag aacctgttgt ttttgaccat gactgtcgtg
     5941 aaggaatctg cggtatgtgt tcattgtatg taaacggaca tccgcacgga ccggcaactg
     6001 gagctacgac ttgccagtta tacatgcgcc gtttcaacga tggtgagacc atcacgatcg
     6061 aaccgtggcg ttccgccggt ttcccggtaa tccgcgactt gatggtagac cgttacgctt
     6121 acgataaaat cattcaggcg ggtggtttca catccgtaaa taccggtggt gtacccgacg
     6181 caaacgcaat tcctattcct aagccagacg cagagatggc aatggatgcc gctgcttgta
     6241 tcggttgtgg cgcttgtgcc gccgcttgta agaacggttc agctatgttg ttcgtatccg
     6301 ctaaggttag ccagttggct ttattacctc aaggtaaggt agaggctgcc cgccgtgcga
     6361 aagcaatggt cgctaaaatg gatgaacttg gcttcggtaa ctgtacgaac acacgtgctt
     6421 gcgagatgga atgtccgaag aatatctccg ttagcaacat cgctcgtttg aaccgtgagt
     6481 tcatttgcgc taaattacaa gactaatatt tgattagtat atcatggaaa aggcgtcttt
     6541 ctctaaaaga aaggtgcctt tttatttttg ttatatgttg aaaaacataa tttagcacta
     6601 cagatcttga caggaattga aaagtccgta tatttgcatc gtggtttttt cataatagta
     6661 ttagatttaa ggttaacaaa gtttggttag ggcttgtcgt gagacaggct ttaattgttt
     6721 atagacctac cttttaaaca tggaccacaa aatactgcaa atagagattg tttagcgtca
     6781 ttttatcgtc gatctttgcc tttaaagatc atataatata tgctaataag tattttattt
     6841 ggcttcttat gttattttct ccgggtgttg atcaaacaca aggaaaaaat catgcgccag
     6901 ataagacaaa tggtaaaaca aaaataaaat ggacaaaaaa cgaaccacca gttctttcag
     6961 ggcaatgagc acggaaagaa aactcgagtc gatcttcctt ttcgtaacag gccgatgcaa
     7021 cgccaaatgc gcgatgtgct tctatgccca agaaatggat aagaagcaac ccgacctcac
     7081 tttcgatgaa atcaagaaaa tatcagaaac cgctgggcaa ttcaaccgat tatggatatc
     7141 cgggggtgag cctaccctgc gtgaggatct accggaaata ttggagttat tctacaaaaa
     7201 caaccatatc aaagatgtga acatccctac gaacggctta aaaccagacc ggatcgtcga
     7261 atgggtaaaa cggttccgcc agaactgccc ggattgtaat attaacgtaa gcctttcctt
     7321 ggatggtttc ggtacgaccc acgatacaca gagaggcgta ccgggaaact tctataaggc
     7381 actggaaacc ctgcgtaaga tacaggagaa tttcggagat gacggcaagg tcctgaaaaa
     7441 tatagcaacc gttatcacga aatacaatat agaccaggta gaagacttca tgacttgggt
     7501 atacggacgc ttccgtacct ccacacatac gattgaggcc gccagaggca tgacccgtga
     7561 cgatggcgtg aaaatcctaa ccgagtcaac gctacgcaaa atacaagacg acatatcccc
     7621 tatctattca gcttatgcgg atcggatggt agcggatacc accggcttaa ggaaaccgat
     7681 cacgcacttc ttctatctcg gccttatacg taccttatat aatgtacgtg ccagcaacat
     7741 agatcaccca accccttggg ggatggattg tacggccggg gagactacct tggtaatcga
     7801 ctacgacgga cgttttcgtg cctgtgagtt acgggaaccg ctcggaaata taaaagagta
     7861 tggttgcgat ataagtaaag tgatgaatag cgaagcgatg aaacaggaaa tagccgctat
     7921 cggacatggg tataaagcca actgttggtg tacgcacggc tgctggatca cctcatccgt
     7981 cattttcaat ccacgtaaga tgattcgctc cgtatataaa ggataccggg aaacgaaacg
     8041 attgaatcat cccttagcca tcaatgagca gaaactacaa acgatggaag ccaaatacca
     8101 tctggacatc gagcgtttgc gtcaactgaa tatccggtaa acaagaccct catagcccat
     8161 aaataaacgt agcatgaaaa tactattagt aaccagaggc tcacaaggcg acgtccttcc
     8221 ttatttggcc atagcggccg aattggaaag acgcggtcat gaggtgacca tcaatctccc
     8281 tcaaatattc gaggagaccg ttaaacccta cggatttaaa tacgtattgc aacagtttga
     8341 cgatatcggc ggcatgatcg atagcgcagc gcaaaactca cataaattcc ggccattcct
     8401 taaatggatg cggaacgtga tcgataaaca gttcgatcaa ttgattcccc tactaaaaga
     8461 gcatgatatt ttagtatcga ccaactcgga atttgctgtc gcaagtatcg ccgagtattg
     8521 caagaaaccc ttgatacgta ccgcctacgc cccgttcttg ccgggtaaga agattccccc
     8581 ggccgtattg ccatttccca aacccaaccc gatcatcact cccgctatcc tatggaagtt
     8641 gatgaaccgg atgaccaatt tcatggtcaa agacacgatc aataagaacc gggctaaata
     8701 cggactcgcg ccgattcgca attttggcta tcacgcggga gagcgttcat ataattactt
     8761 gcttttcagc cagcacctag gaaacgtaga tccggactgg acgttcgaat ggtcgatcgg
     8821 aggctattgc ttcaatgaca cttttcaata tgatgagaag gcttacgagg aaatgatatc
     8881 attcgtcgac agcgctcaaa gccctattat cttttttacc ctcgggagtt gtagttccaa
     8941 ggatggtaac cgtttcagca aagccttggt cgatatttgc aagaaacatg attatcggct
     9001 catcatcggt tccggttggg caaagacagg aatcacctta caagcggata aacatttatt
     9061 cttaatgaag cagccggttc cgcataattt gatattcccg cactgcgacg gcgttatcca
     9121 tcatggaggt tgcggcacga cccatagcgt aggaagggcg ggaaagcccc aattaatcac
     9181 tccgttgatt atcgatcaac cctattggtc ctatcgaatc caccaattag ggttagggcc
     9241 ggaaggagtt aagatagcga aagcgagcga gcaggagatc gaacgcaagg tttgtgatct
     9301 ggtcaccaat ccgctttata agaaaaatgc cgctcatata ggcgagatga tccaaaaaga
     9361 gggaggtata aagaatatat gcgactctat cgaaagattt caatgaggca taagttccta
     9421 ttagatttta ttacatgtta caaaacacaa tttagcactt aaactgttga caaataacag
     9481 taactccgta tatttgcatc gtggttttnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntcgtgag
     9901 acaggcttta attgttttat gaggtctgct tcccgcaaag cccttcgatt acatcagaat
     9961 aatccgatac gtcaataaag tcgatatctt gtcttttaag atcttcccat taatcggttt
    10021 cgccgtatag gcatcaaatc cacttttaat aatccgctgc tcatcttggg cgaaagcgta
    10081 agccgtcacc gcgataatag gtacgctgga agaaacctta cgaatctctg cggtagcctc
    10141 atatccatcc atgaccggca tctttatatc catcaagatc aattgcggtt tgtgctggtg
    10201 aaatagctcc acagcctcct ttccattcca tgcatggatc aatttatatt caggtttcaa
    10261 tatagactca aacaggcggt aattactgga attatcctca gcgatcaaga tcgtaagctc
    10321 attacgggcg atcttgtcca aagtaacagg cttcggctct ccagcgggta ataattcttt
    10381 cttcggctga aaaggcaatg taaaccagaa cttagagcct ttcccttcca cggaatcaac
    10441 cccgatcgtt cctttcatct gggtaacaat catctcacag atacttaaac ccaatcctgt
    10501 tccttgagcg aaagtattca gtttcacaaa acgtccgaag atatctttcc gtttattctc
    10561 agggattccg cagcccgtat cctctacata gaaccacaac gtattatcat cccgcagttt
    10621 atagccaaat gagatcgatc ctgtcttcgt aaatttcatg gcattgttca acagattgat
    10681 catcagttga gacaaacgat ttcgatccgt ataaatcacg caaggctcca gataatcctg
    10741 aaatgagatc tgtacgtccg gattcttatt cttcaaatga accgattgct ccaaatccct
    10801 caaaacagcg ttaatatcca cataatcata agtaaactcc aaggtacccg cctcaatctt
    10861 tgataaatcc aagatatcgt ttatcaactg cagcaatagg gaattattat tctcgataat
    10921 atcagcgaat tccttcttat cctcaaggtc atcggtcgag gcgaggatat tagagaaacc
    10981 tacgatcgca tttaacggcg tacgtatctc atggctcata tttgctaaaa acgctgattt
    11041 caatttattc gactcctccg ccttatccct agccattcga aggtcatgtt ccaattgctt
    11101 acgctcggta atagatatcg tagacccgat caacgctttc ggtttaccgg aagcatcata
    11161 ttcagccatt acctgtatct cctcccactc atggcgatcc tctcccggag tcaattgctc
    11221 cagacaatat tcttttcgta ccttctttat tttcccacta cacaaatccc cgaaagcctt
    11281 ttccacgcaa gccctgaaag acgggtgtat cttgctgaaa tattcctcca acgaaacctc
    11341 atgggtatgc acctctgctg tctctatatt atctcccgga tgtactttcg actcatagat
    11401 aatcttccct tcagccagat tatatcgcca cggtaaaaga tctgccgcct ctaacgccat
    11461 agccagctta tgattcatgg ctttcaaatg cgtctggaaa ttatggatat ccgtaatatc
    11521 aataaaaaac gcgtcaacta cattctcttc cgaggtaggc atgatgataa cagtatagta
    11581 aagccctgtc ggctcaaaat aatactcaca agtaaaggat ttcccactct ccagaaccgt
    11641 aggcacagcc gatagaagca aaggataact tcccccaatc aaattagcga tctcttttcc
    11701 atgcttattt accacgaaat ctttaggagc gattttctcc tcgaaagcat ggtttacatc
    11761 caaaacctgc acatcgattt gcgtaccttc ccgaatcagc cgctgccgta tataaggcaa
    11821 tggcatatta ttaaataaat cgcggtaacg ggataacagc ctcaactcca cttccttcat
    11881 cttttgctta gaacgataca cgtaatgcca cgctaaaaac acgactacca gaaagaaaat
    11941 cagaaagcct aacagcggca tccaatattt ttctaaaaaa gagggaggcg cattcaaata
    12001 gatcgcatca tgtgggaaat tatcttcatt agacatcgcg ctcatcaacg aaacataatt
    12061 caagtattta tgaggatcat ccaccgttga aaccgggatc ttgcccatat cttcaccgtt
    12121 atagacttgc tgtagcaagg gaattagagc agtctcaatc gttttagtac tattataata
    12181 tccaccaatc gtatatcctt cttccacgcc catatcatat aaagaaaaaa caggatgcct
    12241 agaaataccg tttatacctt gatacaaagt actatataat aacgagtgat tcaagaaagg
    12301 tttctcggta atccacgagt aatacatcac tgccgtcgct cgatgtggat ctttctccga
    12361 cagaaccgcc attaaactat ccatggagca agaaccctcc gtataaaaat ccactttccc
    12421 ctcagggaaa gaagtttcca tatgtttctc catctcatcc cgaagccatg tggagacata
    12481 acgtctgtcg gatatgaaaa tcagacgtct caaacccggg attaattcct tcaccaagtc
    12541 gatcgaacct ttaacataat aaggaataac caaccccgta gcgttatacc ccttaaccgc
    12601 ctcttgtaaa ggaatcaccc tatcagagga gtgcctctga ttaaaatagc attcatcttc
    12661 tgccatttca cccgtttccg aacagaccag agagggaata tccccccatt cctcccggat
    12721 cttatcccgc ataaaagccc atccatttac gcctaagtag ataattccac ccggcttttc
    12781 cttatacgtt tcaaagaaaa gcttttgttt ttcttttaac ttctctggcg tatcaaccaa
    12841 tattacgttc atatggtcta ttcgaagagt atactcctcc ggagtagcga acttcgagat
    12901 catgtttaat aaatttccag accaacgttc gctatccata tatgaattta tcaccaatac
    12961 atacgattcc tccttgaccg gatatgagga actcccataa gccggagtcg gcataccggc
    13021 tatcaagcat aaaatcaatc caaaataaag tattattacc tttaaactta taatatttcg
    13081 tatcattccc tacattcgtc tattgcagtt gtaaagacaa agatattcct taattatcaa
    13141 ctaatcttat caaactcgtt tttttatcaa gttttggtgt caaattcacg tttcttacaa
    13201 actaaaggct tttttaatcg ggattattcg gttatttacc gatactcgta tagaaatcag
    13261 cggtatttac ttgtgtatag aatgacgaac ccgtacattt gataaaaaac aaaaaatgga
    13321 acttatggat atgaaagatt atgacatcga ttttaaagag aagaggacaa acgggtatct
    13381 gatcgctacc ttatttatca ttgtcggtat attattttta ctacggaatc taggaatgat
    13441 agatccatcc ttgttcgact tgcttgtatc ttggccgatg ctgcttgtcg tgtcgggcat
    13501 ctttacgatt ttccaccgta atccggtagg aggtatgctc ctcgtgggcg tgggagtcta
    13561 tttccttttc ccgcagttaa attggatcac gaacgatttc ttacgtatat attggccgtt
    13621 aggattaatc ctgttaggat tggtcatcat gctgaagcgg aaagattcta tccgcacgaa
    13681 aaagcataaa cgtcctttta accatccccc tttcgggcac agaaagccta acgatgagat
    13741 caactacgag acagataacg gtttcgtatc ggttgacacc actttcaact cggtaaggca
    13801 catcgtactg gaccccgtat tcaagggagc ggacatagac gtatctttcg gcaacgtgat
    13861 cctcgatctt aaaaaaacaa cattagaggc tgatgaaacc atcataaaca tagatagctc
    13921 cttcagcggc gtagtaatat acgttcctaa aggatggctg gttcgtctaa aggttgattc
    13981 cttcttggct ggatgccaag atatgaggga cctgacagaa acaaccgaca tgacgcacac
    14041 gttatatata tgtggagact tgtcgttcag cggccttgaa ctaagagact aaactcatca
    14101 tgcaagaaca tcctattaca acatccatat tacataaagg gctgggaagc ctattattac
    14161 ttttagccat agcgatccaa tgcgcattat taactcttta tggcgatctt ctgttgagca
    14221 tcactttggt cgatagctta ctttccatcg cattgttcgc cgtagcggga tattatcttt
    14281 ggtatgtaca atgtacgtta catatcatgc aagcacgagt ggctttcgcc gtactcgtac
    14341 aaatcgcttg catagccgga tgctcgatct tgctacaaat attcggattg gaagattggg
    14401 aggaattctc gatcacgatt ccttttcgat tcctgttcgg cctaatggca tggatcattc
    14461 tatcccaatg gtatgccagc cgggaaagaa agagtgaggc ggaacctatc gtgagacaaa
    14521 tggaggaaaa gacggcacct cccccgacta ccgttccgga ggagattcta gatcgtatat
    14581 ccgtaaaaga cgggacacgt attcatatca tcccgataaa agagatattc tatttgcaag
    14641 catgtggcga ctatgtgacc ttattcacca cttccggtca gcacgtaaag gagcaaacca
    14701 tgaagtattt cgagcgaagc cttccttctc cggagttcgt tcgtatacat cgctcttata
    14761 tcgttaatac ggaacagata ttgcgagtag aactattcgg aaaagaaacc tatcaagtac
    14821 gattaaagga tggaacctat cttcgtgcca gtagcgctgg ctataagcta ctcaaagaac
    14881 gtctttccct ttagcagtcc tataaaaggg acctaaccat cgttaaaatt agaagatttt
    14941 gattgtaata tatagagttt tgtgttgtgt aacacttttt ggcaagcatc gatatgttac
    15001 ttaacatata ttagttgcaa aagacttgac aaatggtctt gacgaacgta tctttgcatc
    15061 gtggtttttt cataatnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15361 nnnacaggct ttaattgttt ataggggatt tgcttcccta gatttacata taactataaa
    15421 aaaacggcca cccctaaaaa gaggcggccg taattatacc ataagatagg atttctattc
    15481 ctcaacaata cctacgactt ccatctcaaa aatcatcgta gtgcaaggtt ttacaacaac
    15541 agccccggta ttaggattct tatatcccgc ttctccatat ccaagttgcg agggaaccca
    15601 aatctcccat ttatcaccgg gatgcatatt ctgtaaagcc gtggcaaagc catcagtcat
    15661 cttgtacact tccatcaccg caggctctcc agcctcgaaa gaacgatcat caaaaacttc
    15721 accatt
//
