LOCUS       gnlProkkaCJEAIJCB_31   14023 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJEAIJCB_31.
ACCESSION   gnlProkkaCJEAIJCB_31
VERSION     gnlProkkaCJEAIJCB_31
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 05:21:22
            Original ID  :: gnl|Prokka|CJEAIJCB_31
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 615
            Orig. end    :: 14638
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14023
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12787]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12787
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..14023
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14023
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(722..1288)
                     /locus_tag="ctg31_2"
                     /transl_table=11
                     /translation="MVILELYQGDYQKDLVAFDSLEEGRAFVAQIPGYTLETEDGFGVE
                     FVNPKYLPDYMEIVFNGNIVPLSRFSFNSEENVDIIWKEISNLSVKNDKVIEGYSKIDA
                     YVVNNDEVKAYVEAREANYRKAKDFLERCGYEADRSFFGSEDGEAILYRKKGTEDWKFL
                     CHLDPLFVEIEDVEGYVKEEIQLLN"
     CDS             complement(1468..1812)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 63.3;
                     E-value: 4.5e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_3"
                     /transl_table=11
                     /translation="MQPVGSIGLMIGSASDKGIPDAEAEVGYWIGVLYWGQGLIPEAVR
                     EIMRHGFDDLNLEKMWFGYFDGNTKSKRVQEKCGFRYHHIKEKVPCALEGVFSTEHIAC
                     LSKAEWISIK"
     CDS             complement(2044..2214)
                     /locus_tag="ctg31_4"
                     /transl_table=11
                     /translation="MKPFKSAIAYMPNAKYESPYDGANEMLLVDDVDNKNYLTGLFNAM
                     YDELPAPKPKK"
     CDS             2244..2318
                     /gene="allorf_02859_02933"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_02859_02933"
                     /protein_id="allorf_02859_02933"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKSKYSLLEAIIYTSKICIGLQDF"
     CDS_motif       2244..2285
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKSKYSLLEAIIYT"
                     /locus_tag="allorf_02859_02933_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2286..2318
                     /prepeptide="core"
                     /locus_tag="allorf_02859_02933_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="1105.3"
                     /monoisotopic_mass="1104.6"
                     /core_sequence="SKICIGLQDF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKSKYSLLEAIIYT"
                     /leader_location="[2243:2285](+)"
     CDS             complement(2602..4356)
                     /locus_tag="ctg31_5"
                     /transl_table=11
                     /translation="MKTNNVEIIKADSLVRRRGVNVERHLKRVAAYCRVSSDSEDQKNS
                     YESQVKHYKDYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCVNGEIDYIVTKA
                     IARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVENTSA
                     HVKKGLKMKMQRGELIGFQGCLGYDYDVETKQLSINKKEAKIVRYIFERYLEGIGGKVI
                     ARELDELGYKSPRGLDHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSNFGEED
                     KYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTVANVNGKRERYSKMYAFSSMLECGFC
                     GSLLSRRSWHCRSDYRKVVWHCVTSIKKGKKYCKHSKGLEELAIEGAFMEAYRQLYHSN
                     ENIVSDLLETIESELNDNSLNKELKKITNKLRTLLKKEENLVNLKLEGKISDSIYNEKY
                     NELSLEKEYLAEEKVNVETTLKSEIDVKKRLTEFKQLLSSQKMLTEFDRTVFESIVEKI
                     IVGGVNSDGEIDPAMLTIIFKTGETQNKDGKQFKSKRKNAKLESDELCPQNCDEDKKLY
                     SQGIDNTC"
     CDS             complement(4669..4776)
                     /gene="allorf_05284_05391"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_05284_05391"
                     /protein_id="allorf_05284_05391"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGLSYLSSNLVRYAVIGAKIISYKIEWFSICHNHK"
     CDS_motif       complement(4723..4776)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MGLSYLSSNLVRYAVIGA"
                     /locus_tag="allorf_05284_05391_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4669..4722)
                     /prepeptide="core"
                     /locus_tag="allorf_05284_05391_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.70"
                     /molecular_weight="2110.5"
                     /monoisotopic_mass="2109.1"
                     /core_sequence="KIISYKIEWFSICHNHK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGLSYLSSNLVRYAVIGA"
                     /leader_location="[4722:4776](-)"
                     /alternative_weights="2128.5"
     CDS             complement(4817..5041)
                     /locus_tag="ctg31_6"
                     /transl_table=11
                     /translation="MYQRIRDLREDHDFTQRFVANLLSFSHTNYAKIERGEVALTADVL
                     VQLSKLYNVSTDYLLGLTDYPDRIKHKIK"
     CDS             5136..5360
                     /locus_tag="ctg31_7"
                     /transl_table=11
                     /translation="MIIARANLSFNFARKLLFYSLRKSGLLSFQEQIENQHSDYFMDLS
                     FILSTMLKNYTKNLSSRYSLFSNFLTVNQ"
     CDS             complement(5321..6058)
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MIDYFKAEWIKNRKVVILAIGLIFLALSSFIGLANFFLNYDVLIE
                     EQMSRVLWGQLTFYNGQLLFPAMLAIFSGLIILPEFERKTLEMLRANQASVKKMVLSKF
                     LLALFLVSVVQAVLFAIYLLTLYLSQIPFQIEDLLLFLRATILSVIGSSSVLMIHSYLM
                     AKTRNFAKSVGVAAIGSFSGFIFIMLGGFINQLFPYSQPMIGLRSRALNDMSFLEFMLF
                     ITVNSLYSFIFYWLTVKKLENNE"
     CDS             complement(6121..6885)
                     /locus_tag="ctg31_9"
                     /transl_table=11
                     /translation="MIKVLQIELLKSKRTKSFMISFLMMFVAVTWSLLAASRSIGVPKL
                     RTIGLFFNNLQATPIFLPIAISLFVSRIVSNEKEGNTFKLQEANNINLITIFKRKLIFT
                     NTIFLLLNVVQVLIVYLYAVRYGIDVAVSNLLLQVVGLTMSSFTLITFFLFLSMILEKH
                     GMVLGIGFVSGFLGMVLSEASKWLNLIFPFGGSSFLALYRIKVLHSGDKLDYIFVWDKS
                     VPLNYLIYLFYCIFVYFIIKYLLVKKKEENYD"
     CDS             complement(6887..7798)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 173.8; E-value:
                     7.9e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg31_10"
                     /transl_table=11
                     /translation="MMNNIIELKKVKKVYKDITTVDIEKITVREGEIYGFLGPNGAGKT
                     TTMKMILSLVDPTSGEIFVNKKDIRKDKNYLSQIGSMIEEPSYYPNLTGYENLLVFQKM
                     VGFDENNIWPTLELVGLADEKNRKKLVKAYSLGMKQRLSLAFALVKKPKILLLDEPTNG
                     LDPAGIHEIRELIVELAKEKGLTVFISSHILPEIEHIADRVGIINHGRLVYEGEIEAIK
                     SNTWIEIGGDFSQSNIVHTLVELGTVEILGASTSHVKLSNIDNNQLANVVSYLTENGYR
                     IFRVVRESETLEDIFLSLTKEA"
     CDS             complement(7902..9974)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 128.8; E-value:
                     4.3e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg31_11"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.7e-39, bitscore:
                     123.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIILQNNEEDCLLACYTMLLNDLGHKVPLYEVYDKDSLPADGLN
                     VSYLLSLNKRFGVALKAYHASFRDLLQVYNEKKQRIILHWNQDHFVVLDKITEKQVTIV
                     DPAIGRVKYSHDEFLNHYSETIVLINKDENFQTQKYKQIFWKYFKLTLKTKTIILFLLS
                     LVLIQISVLAFSILLRYMLSEKFQFLSNILVLFGVVLFQLLGYFIKNSALNEYNLDFDD
                     NYSKALFQKLLKKPLLYFRNHLSGGISEKINFKSTLRDNVTLKIIPSCVSFISAIVIFT
                     YLITISVRLTIILIIIILVYSVISIILYRKQNEYNQTYLQYLIDFNSELQTDLDDIDYI
                     KIMRREGLTFASWMKINQQVTEKYSQILKFENLSQLVSTIFNYISLSVIIVIATYYNKY
                     IKVSISDLLVYQTSISLLISAIEQVKGAVFEVVKLGIYAEKQSDLLKDSRPILVQSSDS
                     DEYLIKAESLNFSYGMSPIYKDINLTINRGEKIAIIGKSGSGKSTLLLLLAGMLRFSGS
                     LKYGIKNFEDSLSVVLQNMTLRKGSVLENLEWDTDNLEPLYQVLKDTSADEVIAQLPNK
                     IHSKLLKQGKNLSGGQIQKMLIAKSLLKKNSIIFWDEAFSNLDEQSKNRIYLNILQNSQ
                     YSERTMLIVSHHLDIVDYVDYVIYIDNEMGDVYKDTHINLMESNENYRNFINSKI"
     CDS             complement(10001..12787)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     689.6; E-value: 1.2e-208)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_12"
                     /sec_met_domain="DUF4135 (E-value: 1.6e-82, bitscore:
                     267.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.7e-54, bitscore:
                     174.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQKEQLYSQFDKFPKVVIERLIPEVLNESDSLIKQIEEKISDYY
                     RSTLIYLINEKRINGTLVGETAELRYDFFNNVLCRNGTILDEIEERFPKINQRVFISIK
                     HYLDLLNCVKKHFVSDFLELKKLKFLKSNDESPDLNVLDIKVTGDIHNGSGVCILDYNR
                     QKLVYKKKSSRPNILLKELDSQASNYLKKEIRFIPDFLDKNEYFWEVFVESKPVSSLKE
                     ANEFYKRMGYLLVYSYILNISDLHFENLISHSIQPILVDAETVFSTNPYETVAENDATL
                     KIVENSRNSVLSTGLLPISEADKIFGGDTSGVLGGTLIGEAKVIINHNRDDIHVEKQKY
                     KTENQNHLPYFENNLGIKTYLNAEEYVEYIKEGFIELSKFIINNKEALKKLYLSFSDIK
                     TRVLFRNTRDYSLVRQLLLSPVYCNQDNILFEKMSNKLTNYDSHNLCQSEVKQLLNMDI
                     PYFYVCASDINVKDKDGNTNIWKLKKSSLSDTIEKLEKFDLDTMEEQLDLVEFSIKTPN
                     ALYSTELQESYKIFQNSNSNHSILFTGINTIVDTILKNEKFSKLDGSTNWLTLKVTDYD
                     AFQLEPMDSSIYEGIAGLSIALCEVYKLVDDDRQQRIYNCLRRIFMTLMKAYYSTQNQS
                     YYVGKLGILSAMIRIQSITGQEIPVSIFDINNKYILDLNVQSADFLSSFPSEIVALRNS
                     NVSIGNLQQSFEKLVDLKIISEDYIAWDKLESNNVSLAHGNLGIELGLLYLAVALNSSE
                     AVELFYQATNFDSHQKLSNGWIDKRNNSTSANWCHGSTGVLAARLAQLQLDKKFHIISK
                     TKRSELEADMKHAASQIIEIGFDMTNFSICHGTSGNLLALSYYCSYLSGNEREELEKIL
                     DIEYRKLHSFGLENGWMCSFNTKYNVYGIMNGLSGILYSTAKYLKKDDSLDILIPTL"
     CDS             complement(12807..12968)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_13"
                     /sec_met_domain="L_biotic_A (E-value: 2.4e-26, bitscore:
                     81.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNNNKICQDALESLQELKLEEVDELLGGAGHGVNTISAECRWNS
                     LQAIFSCC"
     CDS_motif       complement(12882..12968)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKNNNKICQDALESLQELKLEEVDELLGG"
                     /locus_tag="ctg31_13_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12807..12881)
                     /prepeptide="core"
                     /locus_tag="ctg31_13_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="0.40"
                     /molecular_weight="2495.8"
                     /monoisotopic_mass="2494.2"
                     /core_sequence="AGHGVNTISAECRWNSLQAIFSCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNNNKICQDALESLQELKLEEVDELLGG"
                     /leader_location="[12881:12968](-)"
                     /alternative_weights="2513.8"
     CDS             complement(13433..13588)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) leader_d"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_14"
                     /sec_met_domain="L_biotic_A (E-value: 3.7e-28, bitscore:
                     87.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="leader_d (E-value: 4.6e-08, bitscore:
                     23.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKETTIIESIQEVSLEELDQIIGAGKNGVFKTISHECHLNTWAF
                     LATCCS"
     CDS_motif       complement(13514..13588)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MEKETTIIESIQEVSLEELDQIIGA"
                     /locus_tag="ctg31_14_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13433..13513)
                     /prepeptide="core"
                     /locus_tag="ctg31_14_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="5.20"
                     /molecular_weight="2778.2"
                     /monoisotopic_mass="2776.3"
                     /core_sequence="GKNGVFKTISHECHLNTWAFLATCCS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKETTIIESIQEVSLEELDQIIGA"
                     /leader_location="[13513:13588](-)"
                     /alternative_weights="2796.2"
                     /alternative_weights="2814.2"
     CDS             13832..14023
                     /locus_tag="ctg31_15"
                     /transl_table=11
                     /translation="MTQFTTELLNFLAQKQDIDEFFRTSLETAMNDLLQAELSAFLGYE
                     PYDKLGYNSGNSRNGSYAR"
ORIGIN
        1 atcctcaatt agctcattct tagctacagc atctcaccgt gaatgaaata ttcgagacgt
       61 ttagctgcgt tttaccaata aactcacact aagcggttcg gacttaccgt atcatctcgt
      121 cggtgtacct cctcattcta cgagtcctat accccagggc accttctcga ccttcggtct
      181 caccttgtcg catgggcgga acatctgctt ctacttcgct gaggtctcag ctcgtaaaag
      241 cagtgagact gcctccacat gtgatgctag aaaatatcta tattatagac caaaactttt
      301 gttcttttct caattagata attttttagt tcagtacaat tttggtaagg tacgttttat
      361 taatttatcg aacaaattga tacatctcca agtccaaaag agaaattgtc aaagatatcc
      421 tgatagtcga atggaattag ttgccctgtc tggctcataa gagcaaagtc aacgcctaat
      481 tcacgaatga gacagggaca cagtgtaaat ccatttttct caatgataag agccaagtcc
      541 aaagaaggga attcgctcct cctttggaaa ggactgctta tacaagtcgc tgatgattcc
      601 ccagtgttta aaagaattaa atttaatttg ttttaaggtc ataaatttct ccttaattcc
      661 accatctggc aaaatagaag cctttttaaa tataactcac gccacgcctt cgcaacattc
      721 tttagtttaa caactgaatc tcttctttga catatccttc tacatcttca atctctacaa
      781 atagtgggtc taagtggcat aagaatttcc aatcttcggt accttttttt ctatagagaa
      841 tcgcttcgcc gtcttcactt ccgaaaaagc ttctgtcggc ctcatatcca cagcgttcta
      901 gaaagtcttt tgccttgcga tagttcgctt ctcttgcttc gacataggct ttcacttcat
      961 cgttgttaac gacatacgcg tcgatttttg aatatccttc aatcacttta tcgtttttaa
     1021 cggatagatt cgaaatttct ttccaaataa tatccacatt ttcttcagaa ttaaacgaaa
     1081 atctagatag agggacaata tttccgttaa agacaatttc catataatcc ggcaagtatt
     1141 ttgggttcac aaactccacc ccaaacccat cttctgtttc taaagtatac cccgggattt
     1201 gagctacaaa cgctctcccc tcttctaaag aatcaaacgc gactaaatcc ttttgataat
     1261 caccttgata caattccaat ataaccatcg ataaccctcc atttaacctt tacgacgcta
     1321 cgcaaattta tttttcaaat cttacaagca gtgatactac atcaacatga aacgagtgaa
     1381 cctatctgta tgtagaaaca ggtctataga gcttttaacg atcgcataag gttatcattt
     1441 aaaggtatga cctcaacaaa ctaagattta cttaattgaa atccactctg cctttgagag
     1501 acaggcgatg tgttctgtgc taaaaacacc ttccaatgca catggaacct tctcttttat
     1561 atgatgataa cggaacccac atttttcctg aactctcttt gactttgtat tgccgtcaaa
     1621 ataaccgaac cacattttct ccaaattcaa gtcatcaaat ccatgtctca ttatctcacg
     1681 aactgcttct ggtataagcc cctgacccca atacagaact cctatccagt aaccaacctc
     1741 cgcctcagca tcaggaatac ctttatcact tgcagagcca atcatcaaac ctatgctacc
     1801 cactggctgc attgtttctt ttaaaactat agcgtatgtc tcaggtgcgg aaaaataact
     1861 ttttataatt tccctactgt tttcaacact agtatgtact ggccaacctg caatcggacc
     1921 aatctctgaa cctctggatt actggcatat tggaataaat cattggcatc tctttcttcc
     1981 catgggcgaa gaatcaacct ttccgtttct aaaatcgttt tttctcctta aattccactc
     2041 tgatcatttc tttggtttag gtgcaggtaa ttcatcatac attgcattga ataagccagt
     2101 taaataattt ttgttgtcaa catcatctac caacagcatt tcatttgctc catcatatgg
     2161 tgactcgtac tttgcatttg gcatatatgc tattgcagat ttaaaaggct tcactaaaaa
     2221 tctatcatca taaattcaca ataatgaaat ctaaatattc tttgcttgaa gccataatct
     2281 acacctccaa aatttgcatt ggtctacagg atttttaata cttatattag ttcaatatgg
     2341 tgggccttcc gtttctacta tgctacttcg tagctcgtac aagcagtgtt acgcattcaa
     2401 catgatgcgt ccgtgggact caaaaggttc ggagaacctt ttgaggatta gctacgtttc
     2461 actaaaaact cacacactcg gcggttcgct attaccgtat cgtttcgtcg taaactcctt
     2521 actctacgac agctatcgca tgggcggagc atctacttct acttcgctga agtctcagct
     2581 cgtacaagta gtgataccgc ctcaacatgt gttgtctatt ccttgagaat acaatttttt
     2641 gtcctcgtca cagttttgag gacacaattc atctgattct agtttagcat ttttacgttt
     2701 acttttgaat tgtttgccat ccttattttg tgtttctcct gttttgaaaa taatagttaa
     2761 cattgcagga tcaatttcac catcgctatt aacaccacct acaataattt tctcaacgat
     2821 gctctcaaaa actgtacgat caaactcagt gagcattttc tgtgaagaca gtaattgttt
     2881 aaactcagtt agtcttttct taacatcaat ttctgacttc aatgttgttt caacatttac
     2941 tttttcttct gcaagatatt ctttttctaa ggagagctca ttatattttt cattataaat
     3001 tgaatcactt atttttcctt ctagttttaa atttacaaga ttctcctctt tttttagtaa
     3061 agtacgaagc ttattagtta tttttttcag ttccttgttg aggctattgt catttaattc
     3121 agattcaatc gtttcaagta aatctgacac tatattttca tttgaatgat agagttgtct
     3181 atatgcttcc atgaaagctc cctcaatagc cagttcctct aatcctttac tatgtttaca
     3241 gtattttttc ccttttttta tcgaagtaac acaatgccac acaacttttc gataatctga
     3301 acgacagtgc caacttctcc tagacaataa tgaaccacaa aaaccacatt ctaacatact
     3361 actaaaagca tacatttttg aatagcgttc acgttttcca tttacattcg caactgtctt
     3421 tttatttcct gccctacgca acctaatctc ctgagctttc tcaaagtctt ctttagatat
     3481 tataggttca tgattatctt tgatgtagta cttatcttct tcaccaaaat tacttaaacg
     3541 tctcttgctt attggatcca ctgtaaaagt tttgcccatt agaatatcgc ctttatattt
     3601 ttcattcttt atgattccta agactgttgt atcattccaa tgatctaatc ctctcggcga
     3661 tttgtaacct agttcatcaa gttcccttgc tatgactttc cctccaatac cttctaagta
     3721 cctttcaaag atataacgaa ctattttggc ttctttttta ttgattgaaa gttgcttggt
     3781 ttctacatca tagtcatacc ccaagcaccc ttgaaaccct atcagttcac cacgttgcat
     3841 cttcattttt aatccctttt tcacatgtgc agatgtattt tctacttctt gctgtgcaac
     3901 agagctaaga atggttagaa gtaattctcc atccatagta agggtatcaa tgttctcttc
     3961 ctcaaaatat actccaattt gcatatcctt taacattctg acatacttca aagtatctaa
     4021 ggtgtttctt gcaaatctag caattgcttt tgttacaata taatcaattt ctccatttac
     4081 acaatcattg attaagcgtt gaaaatcttg tctctttcct acttgagttc ctgaaatccc
     4141 ctcatctgca tagatatcag cgagttccca atctgaacgc tgagaaatgt aatctttata
     4201 atgtttcacc tgagattcat aactgttctt ctgatcctca ctatcagaac tcactcggca
     4261 ataagcagca acccttttta aatgtctttc aacattgaca cctctacgtc gaactaaaga
     4321 atcagctttt attatttcaa cattatttgt tttcataact gaaattcctc cttttgattc
     4381 tatattaccg cgttcaaata aaaaggtcag ctattttgtg tacttaatac gcagtttgtt
     4441 tctgattttt tcatactcat ttttagatag catatttctt gagtataaaa agttaagcat
     4501 tgataattgc atactatata ttactactga ttgttccaaa acttttcctc ctgataacgt
     4561 gttactctat aatttcctca gtaggtatga ttggttaaat cattcatggg catttcaccc
     4621 gctgtccttt tacgatggca gcctgaacgt tcagaagtat cattgtcctt atttgtggtt
     4681 atggcagata gagaaccact ctattttata gctaataatt ttcgctccta tcacggcgta
     4741 tctcactaaa ttgctcgaca aataagaaag tcccacctcg gtttattcaa ttgtcaatga
     4801 acaaatcaag gagagactat tttattttat gttttatcct atctggataa tctgttaacc
     4861 ctaataggta atctgtacta acgttataga gtttagaaag ttgcactaga acatctgccg
     4921 ttaaggcaac ctctcctctc tcaatttttg cataatttgt atgagagaag gaaagtaaat
     4981 ttgcaacaaa cctttgagtg aaatcatgat cttccctcaa atcccttatc cgttggtaca
     5041 tatagctttc tcctaagaaa agtatatgtc actttcagaa aaaagctggg aaattgtcat
     5101 aatatgacag taattattgc gtcattcctg taattatgat aatagctcgt gcaaatttat
     5161 catttaattt tgcaagaaag ttgttgttct attctttacg taaatcaggc ttactatcat
     5221 ttcaagaaca aatcgaaaat cagcatagcg attattttat ggatctgagt ttcattttat
     5281 ctactatgtt gaagaactac acaaaaaatt tatcatcacg ttattcatta ttctccaatt
     5341 tcttaacagt taaccaataa aaaatgaaac tatacaagga gttcactgta ataaataaca
     5401 taaactctaa aaatgacata tcattcaatg ccctacttcg taaaccaatc atcggctgag
     5461 aatatggaaa taattgatta ataaaaccac ctagcataat aaaaataaaa cctgagaagg
     5521 aaccaattgc tgcaactcca accgatttag caaaattcct agtttttgcc ataagataac
     5581 tgtgaatcat caaaacagaa cttgaaccaa taactgataa tattgtagct ctcaaaaata
     5641 ataataaatc ctctatctga aatggaattt gactaagata aagagttaat aaatagatag
     5701 caaacagcac tgcttgaact acagatacca agaacaaagc taataaaaac ttacttagta
     5761 ccatcttctt aactgatgct tgattagctc gtagcatttc aagtgttttt cgttcaaatt
     5821 caggaaggat aattagacct gagaatatag ctaacatagc tggaaaaagt aactgcccgt
     5881 tataaaaagt cagctgtccc caaagaaccc tactcatctg ttcttcaatc aacacatcgt
     5941 agttcaagaa aaaattagct aatccaataa aactggacaa agcaagaaaa ataagaccaa
     6001 tagctaaaat aactacttta cgattcttaa tccactcagc tttaaaataa tcaatcatag
     6061 ttttcctcct tctttttaac cactacttta cgattcttaa tccactcagc tttaaaataa
     6121 tcaatcatag ttttcctcct tctttttaac caataggtac ttaataataa aatagacaaa
     6181 tatacaataa aatagataga taagatagtt gagtggtaca ctcttgtccc aaacaaatat
     6241 gtaatctaat ttatctccag aatgtaaaac ttttatgcga taaagtgcaa gaaaacttga
     6301 acccccgaaa ggaaagatta gatttaacca tttagatgct tcggatagaa ccatccctaa
     6361 aaaccctgat acaaatccaa ttcctaaaac cataccatgt ttttctaata tcatagatag
     6421 aaatagaaaa aaagtaatta aagtaaaact agacatcgtc aaacctacaa cttgtaatag
     6481 taaatttgaa acagcaacat ctataccgta tctaacagca tataaatata caatcaatac
     6541 ttgtactaca ttcaataata gaaaaatagt attcgtaaaa ataagctttc gtttgaaaat
     6601 ggttataaga tttatattat tcgcttcttg tagtttaaat gtatttcctt ctttttcgtt
     6661 actaacaatt cgggatacaa aaagactaat cgcaattggt aaaaaaatag gagtagcttg
     6721 taaattattg aaaaataatc caattgtcct taactttggt acacctatgc ttcttgatgc
     6781 tgctagtaat gaccaagtta ctgctacaaa catcatcaaa aacgatatca taaatgattt
     6841 tgttcgttta ctcttcaata attcgatttg taataccttt atcattttaa gcctccttcg
     6901 ttaacgaaag gaaaatatct tctagggtct cactttctct aaccactcgg aaaatacggt
     6961 atccgttttc tgtcaaatag ctcaccacat tagctaattg attattatca atattactta
     7021 attttacatg acttgtggat gcacccaaaa tttctacagt ccctagttca actaaagtgt
     7081 gaacaatatt actctgtgaa aaatcaccac caatctcaat ccaggtattt gatttaatag
     7141 cttcaatttc tccttcataa actagacgac catgattgat aatacccact cgatctgcaa
     7201 tgtgttcaat ttctggaaga atatgactag aaataaagac tgtcagacct ttttctttgg
     7261 ctaactcaac aatcaattca cgaatttcat gaatacctgc tggatcaaga ccattagtag
     7321 gctcatctaa taataagatt ttaggctttt ttactaatgc aaacgctaaa gaaagacgtt
     7381 gtttcatacc tagagaatag gccttaacta atttttttcg atttttttca tcagctaatc
     7441 caacaagttc taatgttggc cagatattat tttcatcaaa tcccaccatt ttttgaaaca
     7501 ctaataaatt ttcgtaacct gttaaattag gataatatga aggctcttct atcatagatc
     7561 caatctgact caggtaattt ttgtcttttc gaatgtcttt tttattaaca aaaatctcac
     7621 ctgaagtcgg atctacaagg gatagaatca ttttcatcgt tgtcgttttc ccagcaccgt
     7681 ttggccctag aaaaccataa atttctccct cccgtacagt aattttttca atatctacag
     7741 tagtaatatc tttgtaaact ttttttactt ttttcagctc aataatatta ttcatcatca
     7801 ttatccttta gcaatctatt ttattagact actcctttct ttacattaat aattgtacct
     7861 gttcatctta aagataacat taagaatgta taacgcaagt ctcaaatttt tgaattaata
     7921 aaatttctat agttttcgtt actttccata agattaatat gtgtatcctt ataaacatca
     7981 cccatttcgt tatctatgta aataacatag tcaacatagt cgacaatatc tagatgatga
     8041 ctaacaatca acattgtcct ttcagagtat tgactgttct gaagaatatt aagatagatt
     8101 ctatttttac tttgttcatc aagattactg aaagcttcat cccagaaaat aatagagttt
     8161 tttttcaata aagacttagc aattaacatt ttttgaatct gtcctccaga taaatttttc
     8221 ccctgtttca ataactttga atgaatttta tttggtaact gggcaataac ctcatcagct
     8281 gaagtatctt ttaatacttg atacaatggc tctaaattat ctgtatccca ttctaaattt
     8341 tctaacacgc ttccttttct taatgtcata ttctgtagaa caacactcaa actatcttca
     8401 aaatttttaa taccatattt caacgatcca ctaaatcgta gcatacccgc taaaagtaat
     8461 agtaacgttg attttccact acctgattta cctatgattg caatcttttc acctctatta
     8521 attgtcaagt taatatcctt ataaatcgga ctcatgccat aagaaaaatt taggctttca
     8581 gccttaatta aatactcatc cgaatctgaa ctttgtacta aaattggtct actatctttt
     8641 aataaatcac tttgtttttc agcatatatc cccaacttta ctacttcaaa aactgcaccc
     8701 ttcacttgtt caattgcaga tattaataat gaaatacttg tttgatagac tagtaaatcc
     8761 gagatggata ctttaatata tttattatag taagtcgcta taactataat tacagacaaa
     8821 ctaatgtaat taaaaatcgt gctaactaac tgtgataagt tttcaaactt taaaatctgt
     8881 gaatattttt cagtaacttg ttgattaatt ttcatccacg atgcaaaagt tagaccttct
     8941 cgtctcatta ttttgatata atcaatatca tctaaatctg tttgtaactc tgaattaaag
     9001 tcaatcaaat attgcagata agtttggtta tattcattct gtttacgata aagtataata
     9061 gaaattacac tgtaaaccaa aattattatg atcaagatta ttgttaacct tacagaaatt
     9121 gttattaaat atgtaaaaat aacaattgct gagatgaaac ttacacaaga ggggataatc
     9181 ttcaatgtca cattatccct taaagtagac ttgaaattta tcttctctga aataccgcca
     9241 cttaaatgat ttctaaaata taatagtggt ttttttaaca atttttggaa aagtgcttta
     9301 ctatagttat catcaaaatc taagttatat tcatttaagg cactattctt aataaaatag
     9361 cctaatagtt gaaaaagaac aacaccaaat agaactagta tgtttgacaa gaattgaaac
     9421 ttttctgata acatatatct taataagata gaaaatgcta aaacgcttat ctggattagt
     9481 accaacgaaa gcaaaaatag aataattgtt tttgttttca aagtaagttt aaaatatttc
     9541 caaaatatct gtttgtattt ttgagtttga aaattttcat ccttatttat taacactata
     9601 gtttcagaat agtggtttag aaactcatca tgactgtatt ttacacgacc aatagcggga
     9661 tctacaatcg taacttgttt ttcagtaatt ttatctaata ctacgaaatg atcttgattc
     9721 cagtgaagaa ttattctttg ctttttttca ttgtagactt gtaataaatc tctaaacgac
     9781 gcgtgatacg ccttcaaagc tactccaaat cttttgttta gagatagcaa gtatgataca
     9841 ttaagtccgt ctgctggtaa tgagtcttta tcgtatactt catatagtgg aactttatga
     9901 cctaaatcat ttaataacat tgtgtaacac gctaacagac aatcctcttc gttgttttgt
     9961 aaaataatct tcatacttga gttttccttt ctatctcttt ttaaagagta gggattaaaa
    10021 tatccaacga atcatctttt tttaaatatt ttgctgtaga atataaaatt cctgacaaac
    10081 cattcattat tccataaaca ttatatttag tattaaagct gcacatccat ccattctcta
    10141 aaccaaatga atgtaatttt ctatactcta tatctaaaat tttttccaat tcttctcttt
    10201 catttcctga tagatacgag caataataac taagtgctaa caaatttcca cttgttccat
    10261 gacaaataga aaaatttgtc atatcgaaac caatttcaat tatctgagat gctgcatgtt
    10321 tcatatcagc ctctaattcg cttctctttg ttttagatat aatatggaat tttttatcca
    10381 gctgtaattg agctaatctt gcagctaaca cccctgtaga accatgacac caattagcac
    10441 tagtcgaatt atttctttta tctatccatc catttgataa tttttgatga ctatcaaaat
    10501 ttgtagcttg atagaacaat tccactgctt cagaactatt caatgccacc gcaagataaa
    10561 gtaatcccag ttctattcct aaattcccat gtgctaaact aacattatta gattccaatt
    10621 tatcccacgc aatataatct tcagaaataa ttttcaaatc aactaatttc tcaaaagatt
    10681 gttgaagatt tccaattgat acattactat ttcgtaaggc tacaatctca ctaggaaaac
    10741 ttgatagaaa atctgcactc tgaacattca aatctaagat atatttgtta ttaatatcaa
    10801 aaatagatac tggtatttct tgaccagtaa ttgactgtat tctaatcatt gcagataaaa
    10861 ttcctaactt gccaacataa tacgattgat tttgtgtaga ataataagcc ttcattaaag
    10921 tcatgaaaat tctgcgtaaa cagttataaa ttctctgttg tctatcatca tcgaccaatt
    10981 tataaacttc acataacgca atagacagtc ctgcaatacc ctcataaatt gatgaatcca
    11041 tgggttctag ttgaaatgca tcatagtctg taactttcaa agttaaccaa tttgtacttc
    11101 catctaattt agaaaatttt tcatttttta aaattgtatc aactatagta ttaataccag
    11161 taaataatat gctatgattt gagtttgaat tttgaaaaat tttatatgac tcttgcaact
    11221 ctgtactgta taaagcattt ggggttttaa ttgaaaattc tactaaatct aactgttctt
    11281 ccatagtatc taaatcaaat ttttccaatt tttcaattgt atcactcagt gaagattttt
    11341 ttagtttcca aatattagta ttaccgtcct tatctttaac attaatatca cttgcacaaa
    11401 cgtaaaaata cggaatatcc atgttcaaaa gttgttttac ttcagattga cataaattat
    11461 gactatcgta gttcgttaat ttatttgaca ttttttcaaa caaaatatta tcctggttgc
    11521 agtaaactgg tgaaagcaat aattgtctaa ctagactata atctctagta tttctaaata
    11581 aaacacgtgt ttttatatca ctaaaactta agtaaagttt cttcaatgct tccttattat
    11641 taataataaa tttacttaat tctatgaagc cttctttaat atattctaca tattcttcag
    11701 cgtttaaata cgtttttatt cccaaattat tctcaaagta tggtaagtga ttctggtttt
    11761 cagtcttgta cttctgtttt tcaacatgta tatcatctct attatgattt ataataactt
    11821 ttgcttcacc aataagcgtt cctcctaaaa caccactcgt atcacctccg aaaattttgt
    11881 cagcctcaga aataggtaat aatcccgtag aaagaactga attccgacta ttttcaacaa
    11941 tttttaatgt tgcatcattt tcagctactg tctcatatgg attagttgaa aaaacagttt
    12001 cagcatctac taatataggt tggatactat gagatataag attttcaaag tgtaaatcag
    12061 agatattaag aatataggag taaactaaaa gataccccat tctcttataa aactcgtttg
    12121 cttctttaag tgaggatact ggcttactct cgacaaatac ttcccaaaaa tattcatttt
    12181 tatctaaaaa atcaggaatg aacctaattt cctttttcaa ataattactt gcttgactat
    12241 ctaattcttt taaaagaata tttggtcttg atgatttttt cttataaacc aatttttgtc
    12301 tattataatc tagaatacag actccgcttc cattgtgaat atctcctgtg acttttatat
    12361 ctaaaacatt taaatcagga ctctcatcat tagactttaa aaattttaat ttttttaatt
    12421 ctaagaaatc actcacaaag tgctttttca cgcaatttag taagtctaaa tagtgtttaa
    12481 tactgataaa tacacgctga ttaatcttag gaaatcgttc ctctatttca tctaaaatag
    12541 taccgtttct acataataca ttattaaaaa agtcatatcg aagttctgct gtttcaccaa
    12601 ccaatgtccc attaatgcgc ttttcattaa ttaaataaat caatgtagat ctataataat
    12661 ctgaaatttt ttcctcaatt tgcttaatta gcgagtcact ttcatttaaa acttcaggga
    12721 tgagcctttc aattactact ttaggaaatt tatcaaactg actatatagt tgctctttct
    12781 gattcataat attacctctc taaaaattag caacatgaaa agattgcttg taaactattc
    12841 caacgacatt ctgctgaaat agtatttact ccatggcctg ctccacctaa aagttcatca
    12901 acttcttcta acttaagttc ttgtaaggat tccaaagcat cttgacaaat tttattatta
    12961 tttttcataa tttatcacct catatgttat accgagcata actcgaaaat atttttattt
    13021 atgctttaat tttaaaatcg caacataaag aaaagttaaa gctaatctaa agctaatgtt
    13081 aatttattga taaatcttgt tagttcagaa tcaaacaagg ataaagtaac ttcacattac
    13141 taatttatac ctcttcttaa tattttttac ataagttgta aatcatatac tttctttaaa
    13201 tacacatcac attttatcct tcatcattaa atcgtaaact ttagtgaata caacggagaa
    13261 tatttagtgg gtagaatctc gtcttgacac aaaatacttt acaaatcttt actcctagat
    13321 tctatttttc gataagcaat tctattatct ttaagaatta aaatttctga atataaaaaa
    13381 gaggtttccc tcctttttta atgtaacata ttagacactt agtcatccaa aatcaagaac
    13441 aacatgtggc aagaaacgcc catgtattta ggtgacattc gtgcgaaatg gttttaaata
    13501 cgccattttt tcctgcaccg ataatttggt caagctcttc aagactaact tcttgaattg
    13561 attcaataat tgttgtttct ttttccataa tttatccttt tcttaatttt atttgagtgc
    13621 cgttcttatt ttgagaccaa gtgtctttat ctttgttaca agtaaatttt acaaagttga
    13681 ctttaagata tattaaagaa atcataaagt tattttaaag attttaaatc tttgatttta
    13741 ctggtagtgt aaaataagtt gtgtaaacac aaaaaggaat aaatccgtta tagtagagtt
    13801 gcaaaacatt actagaaaga gatttattcc tatgactcag tttaccacag aactacttaa
    13861 cttcctagcc caaaagcaag atattgatga atttttccgt acttctcttg aaacagctat
    13921 gaatgatctg cttcaagcag agttatcagc ctttttaggg tatgaacctt acgataaatt
    13981 aggctataat tctgggaata gtcgtaacgg aagctatgca cgg
//
