LOCUS       gnlProkkaDIHAIPFB_42    7268 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIHAIPFB_42.
ACCESSION   gnlProkkaDIHAIPFB_42
VERSION     gnlProkkaDIHAIPFB_42
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 05:27:44
            Original ID  :: gnl|Prokka|DIHAIPFB_42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7268
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7268
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5355:7079]"
                     /cutoff="20000"
                     /detection_rule="(APH and HopA1)"
                     /neighbourhood="20000"
                     /product="lanthipeptide-class-v"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5356..7079
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APH and HopA1)"
                     /neighbourhood="20000"
                     /product="lanthipeptide-class-v"
                     /protocluster_number="1"
     cand_cluster    1..7268
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APH and HopA1)"
                     /kind="single"
                     /product="lanthipeptide-class-v"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7268
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-v"
                     /region_number="1"
                     /rules="(APH and HopA1)"
                     /tool="antismash"
     CDS             2..574
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 179; E-value: 2.5e-54)"
                     /gene_kind="other"
                     /locus_tag="ctg42_1"
                     /transl_table=11
                     /translation="MRKLFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQFDKKSLPYRA
                     LKNHWRLFQKDSRKLSLNSFYSKTFRQTLAPHEVVAKTLVFSKELTDYYTLYQLLLFHF
                     QEKRVDGFFELIEENMSKVNHYFKTVFRTFLRHKQYIKNALETDYSNAKLEATNKLIKD
                     IKRLGFGFRNFINFRKRVFITHIMKIV"
     CDS             complement(649..1764)
                     /NRPS_PKS="Domain: PKS_ER (45-210). E-value: 6.9e-12.
                     Score: 36.9. Matches aSDomain:
                     nrpspksdomains_ctg42_2_PKS_ER.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 91.8; E-value: 7.6e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_2"
                     /sec_met_domain="ADH_N (E-value: 4.4e-09, bitscore: 25.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEALAIINTDLLLEECIKNKEDIDILGTTVTSGVVDVIRPNFDVK
                     NSQNDDFVLIHVDAFSCNYRDKALIVKSAINMKNKGSSAKPVSYFGSDFVGTITEVGAG
                     VTDLKIGMRVIPNCYYPYREYEGVATGVVTNEASKGWLKLHKSKVLAIPDDMNDYVAAS
                     FSIGAQTSSSMIRRCNIKSSDKILVTSSRSNTSMFIIKSLLTEGYDVTALTTTDWSMEE
                     LDFVSPANVIKIERGLKSWEELNLGKFDVIFDPFYDLNLLNCIPYLNFNGRYITCGFKN
                     QHSSFEEKTDDVRSNKFNLLMLQAMINNLYIIGNCIGTTEDLRLAISKYNPNNAPIQID
                     KIMDVYHGAEFLDSTYNMQSRFGKVVMTYKD"
     aSDomain        complement(1135..1629)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_2_PKS_ER.1"
                     /evalue="6.90E-12"
                     /label="ctg42_2_PKS_ER.1"
                     /locus_tag="ctg42_2"
                     /protein_end="210"
                     /protein_start="45"
                     /score="36.9"
                     /tool="antismash"
                     /translation="NSQNDDFVLIHVDAFSCNYRDKALIVKSAINMKNKGSSAKPVSYF
                     GSDFVGTITEVGAGVTDLKIGMRVIPNCYYPYREYEGVATGVVTNEASKGWLKLHKSKV
                     LAIPDDMNDYVAASFSIGAQTSSSMIRRCNIKSSDKILVTSSRSNTSMFIIKSLLTEGY
                     DV"
     CDS_motif       complement(1459..1497)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_2_0001"
                     /evalue="4.30E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="ctg42_2"
                     /protein_end="102"
                     /protein_start="89"
                     /score="10.1"
                     /tool="antismash"
                     /translation="FGSDFVGTITEVG"
     CDS             complement(1789..2598)
                     /locus_tag="ctg42_3"
                     /transl_table=11
                     /translation="MDRHQLKVMIKKECKELVTDRGLLISLLTVPIIFSIILPILLLLL
                     GTSQEVSTSIVGLNTFIEKFKVIDYPKYLTMETLPLYAVFTYFFLPLFMLLPIMISTVL
                     ASSSFIGEKEHKTLEGLLYTPLSPRILVLGKALGCAVPAITLSTISVVVYILVVNTVGW
                     RYFGHIILPNVTWLLVTILISPLLVLLSILLVIGSSQYLKNSKSAQGISMIIVAPIFGM
                     LISQSTGVLILGIFETMVFIIALILLVLVAFFVVIKIFNFEKFILNN"
     CDS             complement(2591..3502)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 180; E-value:
                     9.9e-55)"
                     /gene_kind="transport"
                     /locus_tag="ctg42_4"
                     /transl_table=11
                     /translation="MVIEITGINKIIGAKKVINDVSLSINKGQVFALLGPNGAGKTTLI
                     RIILGLLKPDKGSVRLFGEKLTDQSRTDLLLRIGVQNDGNLYENLSVKENLALWGEIYG
                     LGQGTIKNRIDDLKKMFHLEEYIDMTVGNLSKGNRQKVMLARAMFHSPDVLILDEPTTG
                     LDPAAIDEFYQFIKKLKKDGVTIIMSTHYLYGMDDVVDSIGVIFEGNLLISDDVNRLRR
                     QENKVHFKGKFNPKDIKELTSYGELFGNLNDEFTITVDKNDKVADIVKILVLKGNDIYS
                     VYKEIETVKEIYFRIIGGISHG"
     CDS             complement(3492..4253)
                     /locus_tag="ctg42_5"
                     /transl_table=11
                     /translation="MLAIEMKRWIRSKKAILLPMFFLFLSVSSTLAAYYANDLIESMAS
                     ANNGKIILPNITWESLVNSFFKNSAQMGVFVGLYFILSMSNIKRTESLKLFYLTRTKSS
                     FKIYLPKLCSSMFFFIISWLSGLLSTIYVTMVLYKEVSLERILATSVLHLIMVSFVIIF
                     GFFINIIFNMPFVISSLAEILILVFSSLTMVDSFDKYTGLKFLLPKKLIHYQELFNSDN
                     IEIVVYLMIYMAVLIVLVWLIDVIRGVKNGN"
     CDS             complement(4216..5142)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 126.9; E-value:
                     1.7e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg42_6"
                     /transl_table=11
                     /translation="MKKKLIELSDVSISIKQHCILENFSVSFSDETGVIGLVGLNGAGK
                     TSFIKSLFGCYTIRSGKILRFTNDIAYCPDVPDFPTDMTTLEVLEYSRMLANKKSKDLG
                     FYKKILQLVGLSKSINREISYFSRGMKQRLGIASVLVLEAQIIFFDEPTSALDPKGREE
                     VIEILRNLGKTKLVVFSSHILNDVEKIANRIIVIHKGKKIFDDDISNLLDHNSHKILVT
                     LNRDSCLNKLKEILSKKKISCLQDNNTLQFSGLELHDFLRLLNEDICIGIVSIKRDRIS
                     LEQSFANLIERSEYQNVSYRNEKMDTK"
     CDS             complement(5164..5346)
                     /locus_tag="ctg42_7"
                     /transl_table=11
                     /translation="MNNILLIIIPIVMLYTLYLIFFFLDIKNHEVKYFSKIIWFIVCLI
                     SVPLGGIFYFFIGRK"
     CDS             complement(5356..6210)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: HopA1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_8"
                     /sec_met_domain="HopA1 (E-value: 8.3e-33, bitscore: 102.8,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNVNQLTKIINIDIDLDLVTIGNEKFENCSLRKSSDLSQWLYCV
                     LHTGNPSLLHRDKQVQLTEQIQNTVVNEKSILCGEAENILGLSCVNLGGVRVYSEDGES
                     VAISKCRPNLTPGFFLYMNSVTDGKILSNTDRYYIYADKPSKAIEIWSSIVEKLESISI
                     PFTTKVLSQSSSYPRTDAVVVYSTREFSNEIREVILEIADSKYSNDFEQHTSPLCKKLT
                     NVVSFAQQPKYRGKNVSFGESRCENIAYAIKDSLITGLDFQMLLKKRFENSGINPDKIF
                     EEL"
     CDS             complement(6237..7079)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-v: APH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_9"
                     /sec_met_domain="APH (E-value: 2.4e-09, bitscore: 26.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDKFNTPILKKQDSKSAEYVYEWIDDSSTVQEIFQDSLGLPFTK
                     NLYDIFSEISKILARVHKISPTKTDNVNSIKLISRPLIALTPEEYADASGAELECLSLL
                     QNDSKLIQTLNSYMPQDKYKVMIHGDIRLDQFLCSLTNEVWIIDFEEYSFGDALKDLGG
                     IIGSVLFDVYIKIFCDTWELNDEGDNEQVINDYLLKREKALLREVSPLLEHFLQEYQSE
                     CGQNIDIELLSVNLGAFLLERVLSRAKLSFRLSEVDKAILGIGREFIISKYKLTQILS"
ORIGIN
        1 ggctcgcaag ctctttccaa acgcaaaaat cgttcttgat cgtttccaca tcatccagca
       61 ccttggacgt gcctttttaa agacaagaat tgcaattatg aaccagttcg ataagaagtc
      121 actaccctat cgagccctga aaaatcactg gcgactcttc caaaaggaca gccgtaaact
      181 atctctcaac tctttttatt caaagacttt ccgccaaact ttagcaccac atgaagttgt
      241 tgcgaagaca ctagtctttt caaaagagct tactgactac tatacacttt atcagctttt
      301 gctttttcac tttcaggaga agagagtaga tgggttcttt gaactgatag aggagaacat
      361 gagcaaggtc aatcattact tcaaaactgt ctttaggact tttcttagac acaagcaata
      421 tatcaaaaac gcactagaaa cggactattc aaacgcaaaa cttgaagcga ccaacaagtt
      481 gatcaaagac atcaaacgat taggattcgg ttttagaaac tttattaact ttaggaagcg
      541 tgttttcatc acccatatta tgaaaatagt gtaaacaatg attaactatc aaaatacacc
      601 aattcgaaaa agtgttttat tttaatcatc atttaagctg attaaaactt aatctttgta
      661 tgtcattact acttttccaa atctactttg catattatat gttgaatcta aaaattcagc
      721 accatgatat acatccataa ttttatcaat ctgaatagga gcattattgg gattgtattt
      781 actaattgct aaacgtaaat cttcagttgt cccaatgcaa tttccgataa tataaagatt
      841 attaatcatt gcttgtagca tcaacaaatt gaatttattt gaacgaacat cgtcagtttt
      901 ttcttcaaaa gagctgtgct gatttttaaa tccacaagta atgtatctac cattaaaatt
      961 gagataagga atacaattaa gtaaatttaa atcatagaat ggatcaaaaa taacatcaaa
     1021 ttttcctaaa tttaattctt cccaactttt taaacctcgt tcaattttaa taacattcgc
     1081 tggagacaca aagtctagtt cttccataga ccaatccgtt gtcgtaagag ctgtgacatc
     1141 atacccttcc gtcaataggg acttaataat aaacattgaa gtgttagatc gagaactcgt
     1201 aacaagaatt ttatcgctac tcttgatatt acatctccga atcatacttg aagaagtctg
     1261 tgctccaatt gaaaatgatg ctgccacgta gtcattcatg tcatctggaa tagctaatac
     1321 tttagattta tggagtttca accatccttt tgaagcctca tttgtaacga ctcctgttgc
     1381 cactccttcg tattctctat acggataata gcaattcgga attactctca ttccaatttt
     1441 caaatctgtt actcctgcac caacttcagt aattgttcca acaaaatctg aaccaaaata
     1501 gctgactggt tttgctgaag atcccttatt cttcatgttt attgctgatt taactattaa
     1561 tgccttatca cgataattac aagaaaaagc atctacatga attaaaacaa aatcgtcatt
     1621 ttgagaattt ttaacatcaa aattaggcct gatgacatca actacaccac tggttacagt
     1681 tgttcctaaa atatcaatat cttctttatt ttttatacat tcttctaata gtaaatccgt
     1741 attaataatt gctaatgctt ccatatttac ctcctttatt ctaaacaatc aattatttag
     1801 aataaatttc tcaaaattga atatttttat aacaacgaaa aaagcaacaa gaactaataa
     1861 tattaaagct atgatgaaaa ccattgtttc aaagattcct aaaattaata cccccgtgga
     1921 ttgagaaatc aacatcccaa agattggtgc tacaattatc atggatattc cttgtgctga
     1981 cttactattc ttcaaatatt gtgagcttcc aataactaac agtattgata ataaaacaag
     2041 aagtggagaa atcaaaattg taactaataa ccatgttaca ttaggtaata taatatgacc
     2101 aaagtatctc caacctacag tattaacaac caatatataa actacaacag aaatagtaga
     2161 gagagttatt gcaggtactg cacaacctaa tgcttttcct aaaacaagta ttctaggaga
     2221 tagaggggtg tataacaaac cttccaaagt tttgtgctct ttctctccaa taaagctact
     2281 gctagctaat actgtcgaaa tcatgattgg gagaagcatg aataacggta aaaaaaagta
     2341 agtaaagaca gcatacaacg gcaaggtttc cattgtaaga tattttggat aatctataac
     2401 cttaaatttt tcaatgaaag tatttagacc aactatgcta gttgagactt cttgactggt
     2461 ccctaataat aataaaagta ttggtaagat aatactgaag ataattggta cagtaagcaa
     2521 ggaaatcagt aatcctctat ccgtaactag ttctttacac tcctttttta tcatgacctt
     2581 cagttgatgt ctatccatga ctgattcctc caataattct aaagtatatt tctttcactg
     2641 tctcaatttc tttatataca ctataaatat catttccttt taaaactaag attttgacaa
     2701 tatcagctac cttatcattc ttatcaactg taatagtaaa ttcatcatta aggttcccaa
     2761 acaattcgcc gtacgaagtc aactctttga tatctttagg attaaattta cctttaaaat
     2821 gaactttatt ttcttgacga cgtagccgat taacatcatc actgataagt aaatttcctt
     2881 caaatataac acctatacta tcgacaacat catccatccc atataaatag tgggtggaca
     2941 tgataattgt aactccatct ttctttaatt tcttaatgaa ctgataaaac tcatcaatcg
     3001 cagccggatc taatcccgtt gtcggttcat ctaaaattaa aacatctgga ctatgaaaca
     3061 tagctctagc cagcatcact ttctgcctat ttcctttgct gagattacca acagtcatgt
     3121 caatatactc ttctaaatga aacatcttct tcaaatcatc tatccgattt tttatagttc
     3181 cttgacctag accatatatt tcaccccata aagctagatt ctctttaaca gatagatttt
     3241 catatagatt accatcattt tgaactccaa tccgtaatag taaatcagtt ctcgattgat
     3301 ctgttagctt ctcaccaaaa agcctaacac ttcccttatc aggttttaac aaccctaaga
     3361 ttatacgaat cagagtagtt tttcccgctc cattcggccc tagtaatgca aagacctgcc
     3421 ccttattaat gcttaaagaa acatcattaa tgactttttt tgcaccaatt attttattga
     3481 tcccagttat ctcaattacc atttttcact cctcttatga catcaatcaa ccataccaaa
     3541 actatgagaa cagccatata aatcattaaa tatactacta tttctatatt atcgctatta
     3601 aatagttctt gataatgtat tagcttttta ggaagcaaaa acttcaaccc agtatattta
     3661 tcaaatgaat caaccattgt taatgacgaa aaaacaagta ttagtatttc agctaaactc
     3721 gaaattacaa aaggcatatt gaagataatg ttaataaaga aaccgaatat tataacaaag
     3781 gaaaccatta tcaaatgtaa aacagaggta gcaagtatcc tttccaaact aacttcttta
     3841 tataaaacca tcgttacgta aatggtactc aataaaccag ataaccaaga aataataaaa
     3901 aagaacatcg aactacataa tttgggaaga taaattttaa aactactttt tgttctcgtt
     3961 aaataaaata attttaacga ttctgttctt ttaatattgc tcattgacaa tataaagtac
     4021 agtcccacaa atactcccat ttgagcggag ttcttaaaaa atgaattaac taagctttcc
     4081 caagtaatat taggaagaat gatttttcca ttatttgctg aagccatact ttcaattaag
     4141 tcattggcat aatatgcagc taacgttgag gatactgata agaatagaaa aaacataggt
     4201 aaaagtattg cttttttact tcgtatccat cttttcattt ctatagctaa cattctgata
     4261 ctcactcctt tcaattagat tagcaaaact ctgctccaaa ctaattctat ctctcttaat
     4321 agatactatt ccgatacaaa tatcctcatt caacaatcta agaaaatcat gcaattctaa
     4381 tccactaaat tgtaaagtgt tattatcttg taaacaagaa atcttttttt tacttaatat
     4441 ttctttcagt ttattcaagc atgaatctct attcaacgta actaaaattt tatgactatt
     4501 atgatccaat aaattcgaaa tatcatcatc aaatattttt ttacctttat gaataacaat
     4561 aatacgatta gctatttttt caacatcatt tagaatgtga ctagaaaaaa ctactagttt
     4621 agtttttccc aaatttctta gtatctcaat aacttcttct cttcctttag gatccaatgc
     4681 acttgttggc tcatcaaaaa atatgatttg agcctctaac accaaaactg atgcaatccc
     4741 caatcgttgt ttcatacctc tcgaaaaata agatatttct ctatttatag atttagatag
     4801 accaaccaat tgaagtattt ttttataaaa tcccagatct ttgcttttct tgttagctaa
     4861 cattcttgaa tattctaata cttctaaagt agtcatatct gttggaaaat ctggaacatc
     4921 tggacaatat gctatatcgt tcgtgaatct taaaattttt ccagatctaa tagtatagca
     4981 accaaagagg gatttaataa acgatgtctt acctgctcca tttaatccaa ctaaaccaat
     5041 cacacctgtt tcatcagaaa aactaacaga aaagttttca agaatacaat gttgctttat
     5101 agaaatagaa acatcagata gttctatcaa tttcttcttc atagtcacat tcctcttttc
     5161 ttcctatttt cttcctataa aaaaatagaa tattccaccc aacggaactg aaatcaagca
     5221 aacaataaac cagataattt tagaaaaata cttaacttca tgatttttaa tatctagaaa
     5281 gaaaaaaata agatatagtg tgtatagcat tactataggt ataataatta aaagaatatt
     5341 attcataatt gttccctaca attcttcaaa aattttatct ggatttatac cagaattttc
     5401 aaaacgtttc ttcaataaca tctgaaaatc caaacccgta atgagactat cttttatagc
     5461 ataggcaata ttctcacatc tactttctcc aaagcttaca ttctttcctc tatattttgg
     5521 ctgctgggca aacgaaacaa catttgttaa tttcttacaa agtggtgatg tatgctgttc
     5581 aaaatcattg gaatactttg aatctgcaat ctctagtatc acttctctaa tttcatttga
     5641 aaactctcta gtagaataaa caacgactgc atctgttcga ggataactag aactctgtga
     5701 caatactttt gttgtgaaag gtatagaaat actttctaat ttttctacaa tagaactcca
     5761 tatttcaatt gctttcgaag gtttatcagc ataaatgtaa tatctgtctg tatttgacaa
     5821 gattttccca tcagtgactg aattcatata caaaaagaac ccaggagtta aatttggtcg
     5881 gcattttgaa attgcaacac tctccccatc ttcagaatac actctcactc caccaagatt
     5941 tacacaagat aaccctagaa tattttctgc ttctccgcat aaaatacttt tttcattgac
     6001 tacggtgttt tgaatctgtt cagttaattg cacctgctta tctctgtgaa gaagactagg
     6061 gttacctgtg tgcaacacac aatataacca ctgagataaa tcagatgact ttcttaaact
     6121 acaattttca aatttttcgt ttccaattgt tactaaatct aaatcaatat ctatattaat
     6181 tatcttcgtt agttggttca cattagtcat actactctac tcctataaaa taaattctaa
     6241 gataaaattt gagtcaattt atatttggaa ataatgaatt cacgaccaat accaagaatt
     6301 gctttatcaa cttctgatag tctaaaactt aatttagctc gactcaagac cctttccaac
     6361 aaaaatgctc ctaaattcac tgataacagt tcaatatcaa tattttgtcc acattctgat
     6421 tgatattctt gtaaaaagtg ttctaacaat ggagatactt ctcgtaataa tgctttttct
     6481 ctttttagta gataatcatt aatcacttgt tcattatctc cttcatcatt aagttcccaa
     6541 gtatcacaaa atattttaat atacacatca aaaagaactg aaccgattat cccacctaaa
     6601 tcttttaaag catctccgaa cgaatactct tcaaaatcaa taatccaaac ctcatttgtt
     6661 aaagagcata aaaattgatc caatctgata tctccatgta tcattacctt gtatttatct
     6721 tgaggcatat aactgtttaa agtttgaatc aacttcgaat cattttgtag aagtgataaa
     6781 cactctaatt ctgcgccact agcatcagca tactcctcag gggttaaagc aattaatggt
     6841 ctagatatta gtttaatact gtttacatta tcggttttag ttggtgaaat cttatgtact
     6901 ctagctaaaa tttttgaaat ttcactaaaa atatcatata aatttttggt aaatggtaat
     6961 ccaagagagt cctgaaaaat ttcttgaact gtgcttgaat cgtctatcca ttcatacaca
     7021 tactctgcac ttttgctatc ttgttttttt aaaataggag tattgaactt gtctggcaaa
     7081 tctagctgcc actgtctcag atttctctgt ctcctcttta catcatcact attccctaaa
     7141 agtttctttt taatacattt tatattatca ataatgatac tgtcaataat tatgtgtaaa
     7201 cactcaagta gagttgaaga atgttaatca aataagcttt caagtgtgtc agcacattgg
     7261 ccaaaccc
//
