GCA_002834235.1 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaIBCEKGAL_25 (original name was: gnl|Prokka|IBCEKGAL_25)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	RRE-containing	19,077	39,340

gnlProkkaIBCEKGAL_32 (original name was: gnl|Prokka|IBCEKGAL_32)

Region	Type	From	To	Most similar known cluster		Similarity
Region 18.1	ranthipeptide	81,712	103,319

gnlProkkaIBCEKGAL_35 (original name was: gnl|Prokka|IBCEKGAL_35)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	NRPS,HR-T2PKS	15,619	101,633	leucomycin	Polyketide	3%

gnlProkkaIBCEKGAL_40 (original name was: gnl|Prokka|IBCEKGAL_40)

Region	Type	From	To	Most similar known cluster		Similarity
Region 26.1	RiPP-like,cyclic-lactone-autoinducer	353	21,649

Region	Type	From	To	Most similar known cluster	Similarity
Region 11.1	RRE-containing	19,077	39,340
Region 18.1	ranthipeptide	81,712	103,319
Region 21.1	NRPS,HR-T2PKS	15,619	101,633	leucomycin	Polyketide	3%
Region 26.1	RiPP-like,cyclic-lactone-autoinducer	353	21,649

No secondary metabolite regions were found in these records:: gnlProkkaIBCEKGAL_2 (original name was: gnl|Prokka|IBCEKGAL_2); gnlProkkaIBCEKGAL_7 (original name was: gnl|Prokka|IBCEKGAL_7); gnlProkkaIBCEKGAL_10 (original name was: gnl|Prokka|IBCEKGAL_10); gnlProkkaIBCEKGAL_12 (original name was: gnl|Prokka|IBCEKGAL_12); gnlProkkaIBCEKGAL_13 (original name was: gnl|Prokka|IBCEKGAL_13); gnlProkkaIBCEKGAL_14 (original name was: gnl|Prokka|IBCEKGAL_14); gnlProkkaIBCEKGAL_16 (original name was: gnl|Prokka|IBCEKGAL_16); gnlProkkaIBCEKGAL_22 (original name was: gnl|Prokka|IBCEKGAL_22); gnlProkkaIBCEKGAL_23 (original name was: gnl|Prokka|IBCEKGAL_23); gnlProkkaIBCEKGAL_24 (original name was: gnl|Prokka|IBCEKGAL_24); gnlProkkaIBCEKGAL_26 (original name was: gnl|Prokka|IBCEKGAL_26); gnlProkkaIBCEKGAL_27 (original name was: gnl|Prokka|IBCEKGAL_27); gnlProkkaIBCEKGAL_28 (original name was: gnl|Prokka|IBCEKGAL_28); gnlProkkaIBCEKGAL_29 (original name was: gnl|Prokka|IBCEKGAL_29); gnlProkkaIBCEKGAL_30 (original name was: gnl|Prokka|IBCEKGAL_30); gnlProkkaIBCEKGAL_31 (original name was: gnl|Prokka|IBCEKGAL_31); gnlProkkaIBCEKGAL_33 (original name was: gnl|Prokka|IBCEKGAL_33); gnlProkkaIBCEKGAL_34 (original name was: gnl|Prokka|IBCEKGAL_34); gnlProkkaIBCEKGAL_36 (original name was: gnl|Prokka|IBCEKGAL_36); gnlProkkaIBCEKGAL_37 (original name was: gnl|Prokka|IBCEKGAL_37); gnlProkkaIBCEKGAL_38 (original name was: gnl|Prokka|IBCEKGAL_38); gnlProkkaIBCEKGAL_39 (original name was: gnl|Prokka|IBCEKGAL_39); gnlProkkaIBCEKGAL_41 (original name was: gnl|Prokka|IBCEKGAL_41); gnlProkkaIBCEKGAL_42 (original name was: gnl|Prokka|IBCEKGAL_42); gnlProkkaIBCEKGAL_43 (original name was: gnl|Prokka|IBCEKGAL_43); gnlProkkaIBCEKGAL_44 (original name was: gnl|Prokka|IBCEKGAL_44); gnlProkkaIBCEKGAL_45 (original name was: gnl|Prokka|IBCEKGAL_45); gnlProkkaIBCEKGAL_46 (original name was: gnl|Prokka|IBCEKGAL_46); gnlProkkaIBCEKGAL_47 (original name was: gnl|Prokka|IBCEKGAL_47); gnlProkkaIBCEKGAL_48 (original name was: gnl|Prokka|IBCEKGAL_48); gnlProkkaIBCEKGAL_49 (original name was: gnl|Prokka|IBCEKGAL_49); gnlProkkaIBCEKGAL_50 (original name was: gnl|Prokka|IBCEKGAL_50); gnlProkkaIBCEKGAL_51 (original name was: gnl|Prokka|IBCEKGAL_51); gnlProkkaIBCEKGAL_52 (original name was: gnl|Prokka|IBCEKGAL_52)

Compact view

gnlProkkaIBCEKGAL_25 - Region 1 - RRE-containing

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Location: 19,077 - 39,340 nt. (total: 20,264 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaIBCEKGAL_32 - Region 1 - ranthipeptide

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Location: 81,712 - 103,319 nt. (total: 21,608 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaIBCEKGAL_35 - Region 1 - HR-T2PKS,NRPS

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Location: 15,619 - 101,633 nt. (total: 86,015 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
HR-T2PKS: (hr-t2pks-ksa and (t2fas or APE_KS2 or ketoacyl-synt))

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core biosynthetic genes

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NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 15618 - 101633:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 15618 - 62950:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg21_39

Search NORINE for peptide: strict or relaxed

AMP-binding (457..845): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DASFLGGVYK
Nearest Stachelhaus code(s):: Ile DALFMGGVYK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (1479..1869): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMKNLGTVSK
Nearest Stachelhaus code(s):: Asp DMKDLGMVDK (53% 8Å match)
Stachelhaus code match:: 70% (weak)

gnlProkkaIBCEKGAL_40 - Region 1 - RiPP-like,cyclic-lactone-autoinducer

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Location: 353 - 21,649 nt. (total: 21,297 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.