LOCUS       gnlProkkaGFBIJKNM_49    2199 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GFBIJKNM_49.
ACCESSION   gnlProkkaGFBIJKNM_49
VERSION     gnlProkkaGFBIJKNM_49
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 06:02:54
            Original ID  :: gnl|Prokka|GFBIJKNM_49
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2199
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2199
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:2199]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2199
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2199
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2199
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             1..2199
                     /NRPS_PKS="Domain: AMP-binding (18-408). E-value: 2e-119.
                     Score: 390.7. Matches aSDomain:
                     nrpspksdomains_ctg46_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (516-581). E-value: 3.8e-22. Score:
                     70.2. Matches aSDomain: nrpspksdomains_ctg46_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 364;
                     E-value: 1.7e-110)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_1"
                     /sec_met_domain="AMP-binding (E-value: 2e-128, bitscore:
                     414.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.4e-14, bitscore:
                     39.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.4e-32, bitscore:
                     98.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFNDTKAEYPRNKTIHQLFEEQAERVPDKVAVVFEDKQLTYRGLN
                     ERANRLARTLRNEGVEADQLVGIMAERSLDMIVGILGILKAGGAYVPIDPEYPEERIHY
                     MLEDSKAHLLLTQSHLRDRISFAGKILSLDEEDSYDEAESNLKSIVEPHHLAYVIYTSG
                     TTGKPKGVMVEHRGLCNLTTYFKENLQMNEHDRVVQFASISFDAAVWEVFTSLLLGAKL
                     YIPKKLEIIDHHLFVKFMNDKKITTALLPPTYIRYLTPENFSSLKRLITGGSAITVDLM
                     TKWKENLLYLNAYGPTEDSIITTVWKGLEENIQPYIVPIGRPIPNHNVYILNTSDQLQP
                     VGVPGELCISGVGLARGYLNRPDLTAEKFVDHPFIPGEKLYRTGDLARWLPEGNIEYLG
                     RIDHQVKIRGYRIEIGEIETALLNLEAVQEAIVVAHENNNGDKALCAYYVASESFAVSE
                     MKEKLSVQMPSYMIPSYFIQLEKMPLTSNGKIDRKALPLPDEKSIQTGVEYIAPCTPTE
                     QALVTAWESVLGVKRIGLLDNFYDLGGDSIKSIQVSSRLFQAGYKVEMKHLLKYPTIAQ
                     LSGYVECITSVAEQGEITGAAPLTPIQSWFFEENFVDHYFNQAMMLYRPDRFDTAILRK
                     VIGQIVQHHDALRTVFVKQENEFTAWIRGIAEGELFTLDVFDLQEEQDCAQIVEARANQ
                     IQSSIKINEGPLIKLALFQCPDGDHLLIVIHHLVIDMVS"
     aSDomain        55..1224
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg46_1_AMP-binding.1"
                     /evalue="2.00E-119"
                     /label="ctg46_1_AMP-binding.1"
                     /locus_tag="ctg46_1"
                     /protein_end="408"
                     /protein_start="18"
                     /score="390.7"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEEQAERVPDKVAVVFEDKQLTYRGLNERANRLARTLRNEGVEAD
                     QLVGIMAERSLDMIVGILGILKAGGAYVPIDPEYPEERIHYMLEDSKAHLLLTQSHLRD
                     RISFAGKILSLDEEDSYDEAESNLKSIVEPHHLAYVIYTSGTTGKPKGVMVEHRGLCNL
                     TTYFKENLQMNEHDRVVQFASISFDAAVWEVFTSLLLGAKLYIPKKLEIIDHHLFVKFM
                     NDKKITTALLPPTYIRYLTPENFSSLKRLITGGSAITVDLMTKWKENLLYLNAYGPTED
                     SIITTVWKGLEENIQPYIVPIGRPIPNHNVYILNTSDQLQPVGVPGELCISGVGLARGY
                     LNRPDLTAEKFVDHPFIPGEKLYRTGDLARWLPEGNIEYLGRIDHQVKIR"
     aSModule        55..1743
                     /complete
                     /domains="nrpspksdomains_ctg46_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg46_1_PCP.1"
                     /locus_tags="ctg46_1"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       241..282
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg46_1_0001"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg46_1"
                     /protein_end="94"
                     /protein_start="80"
                     /score="20.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPID"
     CDS_motif       466..525
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg46_1_0002"
                     /evalue="9.30E-12"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg46_1"
                     /protein_end="175"
                     /protein_start="155"
                     /score="36.5"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGKPKGVMVEH"
     CDS_motif       1018..1107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg46_1_0003"
                     /evalue="2.50E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg46_1"
                     /protein_end="369"
                     /protein_start="339"
                     /score="61.3"
                     /tool="antismash"
                     /translation="PVGVPGELCISGVGLARGYLNRPDLTAEKF"
     CDS_motif       1189..1254
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg46_1_0004"
                     /evalue="5.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg46_1"
                     /protein_end="418"
                     /protein_start="396"
                     /score="37.5"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGYRIEIGEIE"
     aSDomain        1549..1743
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg46_1_PCP.1"
                     /evalue="3.80E-22"
                     /label="ctg46_1_PCP.1"
                     /locus_tag="ctg46_1"
                     /protein_end="581"
                     /protein_start="516"
                     /score="70.2"
                     /tool="antismash"
                     /translation="EQALVTAWESVLGVKRIGLLDNFYDLGGDSIKSIQVSSRLFQAGY
                     KVEMKHLLKYPTIAQLSGYV"
     CDS_motif       1795..1824
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg46_1_0005"
                     /evalue="2.10E-04"
                     /label="NRPS-E1"
                     /locus_tag="ctg46_1"
                     /protein_end="608"
                     /protein_start="598"
                     /score="14.2"
                     /tool="antismash"
                     /translation="LTPIQSWFFE"
     CDS_motif       1879..1956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg46_1_0006"
                     /evalue="1.40E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg46_1"
                     /protein_end="652"
                     /protein_start="626"
                     /score="24.0"
                     /tool="antismash"
                     /translation="RFDTAILRKVIGQIVQHHDALRTVFV"
     CDS_motif       2158..2199
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg46_1_0007"
                     /evalue="2.50E-04"
                     /label="NRPS-E2"
                     /locus_tag="ctg46_1"
                     /protein_end="733"
                     /protein_start="719"
                     /score="13.8"
                     /tool="antismash"
                     /translation="LLIVIHHLVIDMVS"
ORIGIN
        1 gatttcaatg acacaaaagc ggaatatcca agaaacaaaa caattcatca actgtttgaa
       61 gaacaagcag aacgtgtacc agataaggta gctgttgtgt ttgaagataa acaattgaca
      121 tatcgtggac tgaatgagcg cgctaatcga ctagcccgca cacttcgaaa cgaaggtgta
      181 gaggctgatc agctcgttgg gattatggca gagcgttctt tagacatgat cgtgggcata
      241 cttggtatcc ttaaggccgg gggagcgtat gtaccaattg atccggagta tccagaagag
      301 cgaatccatt atatgttaga agattcaaaa gcacacttat tattaaccca aagtcatttg
      361 cgagatcgaa tatcgttcgc tggaaagata ttgtcccttg atgaagaaga cagctatgat
      421 gaagctgaat ctaatctgaa atctattgtg gaaccacacc atttggcata tgtaatatat
      481 acttcaggaa cgactgggaa accaaaagga gttatggttg agcatagagg gttatgtaat
      541 ttaacaacat actttaaaga aaacttgcaa atgaacgagc atgaccgagt ggtacagttt
      601 gcgagtatct catttgacgc agctgtttgg gaagtattta cttccttatt attaggggct
      661 aaattatata tacctaagaa attagaaatt atagatcatc atttgtttgt taaatttatg
      721 aacgataaaa aaattacgac ggcgttatta cctccaacgt atataagata tttaactcca
      781 gagaattttt cttctttaaa aagattaatt actggtggat cagctataac agtagatttg
      841 atgacaaaat ggaaagaaaa tctattgtat ctcaatgctt atggtcctac agaggattct
      901 atcataacaa cggtgtggaa agggttagaa gagaacattc aaccttatat agtaccaatt
      961 ggtcgtccca ttcctaatca taatgtatat atattaaaca ccagtgatca attacagcct
     1021 gtaggagtcc caggagaatt atgtatcagt ggagttggtc tagctcgagg ctacttaaac
     1081 cgcccggatt taacggccga aaagtttgtt gaccacccgt ttatccctgg tgagaaattg
     1141 tatcgaactg gagaccttgc cagatggtta ccggaaggta acattgagta tttaggacgg
     1201 attgaccatc aagtaaaaat acgcggatac cggattgaaa ttggagaaat tgaaacagct
     1261 ttattgaatc tagaagctgt acaagaagca atcgtggttg cgcatgaaaa caacaatgga
     1321 gataaagcgt tatgtgcata ctacgttgcg agtgaatctt ttgcggtcag tgagatgaaa
     1381 gagaaattat ctgtccaaat gccaagctac atgatcccat cttattttat tcagctggag
     1441 aaaatgccgc tgacatctaa cgggaaaatt gaccgtaagg cactccctct gcctgatgag
     1501 aaaagtatcc agacaggggt tgagtatata gcaccttgta caccgactga acaagcttta
     1561 gtgacggcat gggaatcagt attaggggta aaacgcattg gattattaga taatttctat
     1621 gatttgggcg gagattcaat taaatcgatc caggtatcat caaggttgtt tcaagctgga
     1681 tacaaagtag aaatgaaaca tttgttaaag tacccaacga ttgcgcaact cagcggatat
     1741 gttgaatgta ttacgtctgt tgctgaacag ggagaaatta cgggtgcggc accattaact
     1801 ccaattcaat cgtggttctt tgaagagaat tttgttgacc attattttaa tcaagcgatg
     1861 atgttgtatc ggccggatcg ctttgatact gccattttga gaaaagtgat aggtcaaata
     1921 gttcaacatc atgatgcatt acgaacagta tttgtaaaac aagagaatga attcacagcc
     1981 tggatacgcg ggattgcgga aggagaatta ttcacattag atgtgtttga tcttcaagag
     2041 gaacaggact gtgcacaaat tgtagaagct agagctaatc aaattcaaag cagtataaag
     2101 attaatgaag gtcctttaat caaattggca ctgttccagt gcccagatgg cgatcattta
     2161 ttaatcgtaa ttcatcactt ggtcattgat atggtatct
//
