LOCUS       c00003_gnlPro..        13866 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NBFJEINF_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:50:42
            Original ID  :: gnl|Prokka|NBFJEINF_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 39634
            Orig. end    :: 53500
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13866
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[49634:53124]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13866
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13866
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(337..1392)
                     /locus_tag="ctg3_48"
                     /transl_table=11
                     /translation="MLTALNDFTLDELKKDSSDLDDPSKLENAIRIKHHNLIKSFLQQK
                     SSFLAEIGFDLDTIQKIISIGEAHRSIKLSKLPEKIKYLGALLRLADEMDIGPSRAPIS
                     AFNSLYEDMEPLSKWNWYKHIITKQWELGNTYDYANLNGTNYIYLKPAVLPAKEESISH
                     WLLQVCRPIEKALNDEQCREIIRRKYNVEIECKRDPNLSSVNPFYLNYLKIENDILSRG
                     SKPIILSVDDEVDKLRDTFYFFQDRYYVHIVPHPSSALKYLRAAPVTLLIVDIQISWDA
                     TWGDDPDLDEHQAGVFFIKKVKEEFPDLKICVLTGTRHPLPQILHGLVDEIIRKPIDPI
                     ELLQTINAIIE"
     CDS             1770..1901
                     /locus_tag="ctg3_49"
                     /transl_table=11
                     /translation="MADREGFEPSVPVCGTHTFQACSFDHSDTCPLEIVLDRKAGIE"
     CDS             2558..3577
                     /locus_tag="ctg3_50"
                     /transl_table=11
                     /translation="MGESFYTRTTEAPSSAFDLSLRPPAFSEFCGQEKIKDRLMLMVEA
                     ARQRDDVLDHILLSGPPGLGKTTLANIIANAVGCRIHTTSGPQIEKAGDLAGVLTNLEK
                     GDILFIDEIHRLHPAIEEYLYPAMEDFRLDIIIDQGPNARSIQLNLPKFTLVGATTRAG
                     MLTSPLRSRFGLVNRLDYYTREELCAIIERSAGLLNVPVDPEGALQIALRSRGTPRVAN
                     SLLRWVRDYAQVRGDGVITEQLAHDALTMIEIDDDGLDEMDKRLLEAMIYKFNGGPVGL
                     SSLAVAVGEDASTLEDVHEPFLIMQGYISRTPRGRVAMPSAYLKMGAAPPANGQGWLL"
     CDS             3699..4718
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiolase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_51"
                     /sec_met_domain="Thiolase_N (E-value: 4.2e-10, bitscore:
                     31.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III (E-value: 5.1e-33, bitscore:
                     104.9, seeds: 136, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III_C (E-value: 1.7e-38, bitscore:
                     122.8, seeds: 152, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAHSDISFKRLPVKIIGTGSYVPERRLTNADLEKMVDTSHEWII
                     ERTGIVERRIAAPDEYTSHMGTKAAQRALESCGLKPEDIDLIIVATITPDTFTPSTSCY
                     IQDALGAKNAAAFDISAACSGFLFAMKTAVQYIGTGQMKTALIIAAEKLSTVVNWEDRS
                     TCVLFGDGAGAAVLQASTGEEGEGSVLATDIGSDGSLHDLLQIPGGGSRCPTTAENAHE
                     RLATLAMRGNETFRHAVTRMKASAASVIERAGLTADDIQLIIPHQANLRIINAVAQRLS
                     IPEDKVFVNIEKYGNTSAAAVAIAFDEARRSGRFGKGDNVVLVTFGAGLTWSAAVIRW"
     CDS             4746..5876
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_52"
                     /sec_met_domain="NAD_binding_1 (E-value: 9.8e-20, bitscore:
                     63.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEPYGKKNPFPAPVLSVKHITGEGSPKETIHIEYSLDGSGMNY
                     IAGDALAVIPANDPALADALIDKLGLSPDSQVPTPEGETASLKDALVHCYDITNVNKAL
                     LTKWAAASGSQELDALLAGDKDALNDFLWGRDMLDLATEYPASFKSAEAFTGILKKIMP
                     RLYSIASSPNAHPEQVHLCVGAVRYTARDRKRGGVCSTYMADRLQPGHTARVFVHTNKN
                     FRLPEDGDTPIIMVGPGTGIAPFRAFWEERAASGAKGGNWLFFGNPYRATDFCYEDELN
                     QLTGTGKLKLSVAWSRDQEKKVYVQHLMVQEGEELWKWLEAGACFYVCGDASRMAKDVD
                     NALHEVIQTWGHKTPEEAAAYVADMKQHRRYQRDVY"
     CDS             complement(6138..7157)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_53"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.5e-16,
                     bitscore: 52.0, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSSRLPSISIILTGHNQEHCIQDAIRSVFGQDYEGPVEIILSDD
                     GSSDGTFAVMQEMAAQYRGPYRVILNRNETPLGRGPHIRQAVGLASHEWILRQDGDDCS
                     FPWRCRFFAWAVMEYPDAVAVVSQMINVYEEPGVAFEFPAFPSVPREMPAVVLQQGAFS
                     SSAHYGPAMIIRKSAYEWGNAFPITANFEDDLMAFHAWLQGNIYELPDTALCYYRFAAQ
                     NISAVSSAFRFADMQTAEAFERKDLVMLEQLKESVEAGMKLCGELLESFVLVFRSRKEL
                     LAEIEERRKKISYIDQLQNWWNYSFSQRWFLKRTRKKGYSPLFAAKAVFILHGLLFQA"
     CDS             complement(7108..7275)
                     /locus_tag="ctg3_54"
                     /transl_table=11
                     /translation="MYLCLNNEFRIRYEHDVLYVNGEEQYSFRFFHFLFCTFFHEFFAT
                     PFHQHYPDRA"
     CDS             7313..8020
                     /locus_tag="ctg3_55"
                     /transl_table=11
                     /translation="MNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASVPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(7921..8178)
                     /locus_tag="ctg3_56"
                     /transl_table=11
                     /translation="MPFPRQVLAVRLPQQMEASSPCFFRQMFERIRKRPTHDFVSRPLN
                     IGRRTVQAYALRRRIISAASPSRPREAVAGSGTLAISLIS"
     CDS             8451..8684
                     /locus_tag="ctg3_57"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAASAYILTPD
                     EFLFDGIGKLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9522)
                     /locus_tag="ctg3_58"
                     /transl_table=11
                     /translation="MAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSVDG
                     FRDYFVQLTEGEPARAAKFGMDHYTWLCINPKEAQDVAFAREVMKLIPEFIDRPNVLGI
                     GEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDP
                     CRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWG
                     DSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg3_59"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     EVLPLLSASGPGRVRAILEALSYRDDAVPETAAAKAACGAPNFSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_60"
                     /sec_met_domain="SucD_FumR (E-value: 1.3e-12, bitscore:
                     39.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLGVIFIIHVWLTIQLKLENNAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLVYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVAGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPLYNFVAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10751..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.2; E-value:
                     4e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_61"
                     /sec_met_domain="FAD_binding_2 (E-value: 4e-54, bitscore:
                     176.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 120.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVLVVGSGLAGA
                     SAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKGGD
                     FRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRTFYARGQTGQ
                     QLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEIKSYAGDTVL
                     LCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVKGDYQSKLTL
                     MSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFGNLAPRDISS
                     RAAKEACDDGRGVAITGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEITDDDPHETP
                     MMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQGLSDGYFVI
                     PATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFHRELGLIMWE
                     DCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVADFLEFAQLLC
                     YDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLHKEPLTFENV
                     HLAIRSYK"
     CDS             12723..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_62"
                     /sec_met_domain="Fer2_3 (E-value: 2.2e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 7.4e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 gttcataata acataaaaca cgacattttg aatcatcgta tttaattagc tcaaaaatat
       61 ctgtaaaatc ttttttatca atagaaattc catgttgatt tttagtatga attaaaatat
      121 atttaacaaa atttataaaa gcatattttt ttgcattttc aaaaggatct ataggaattc
      181 cataatttga agcaatagtc agatctaatt cgtcatttat attttgacgc aaaaatagag
      241 aaaaaaccat tggtttatta ttacatttac tatctagtga atctagaaaa aatttccata
      301 ataatttctc agttggctct tgtgttcttg ttctcattac tcaataattg cattaatagt
      361 ttgtaataat tctattggat ctataggttt ccgtataatt tcatctacta aaccatgaag
      421 aatctgaggc aacggatgcc ttgttcctgt taatacgcaa attttgagat caggaaattc
      481 ttctttcacc tttttaataa aaaatacacc tgcctgatgt tcatccaagt caggatcatc
      541 tccccacgta gcatcccaac taatttgtat atctactatc aataacgtaa ctggagcagc
      601 tctcaaatat tttagagcag aactaggatg aggtacaata tgcacataat atctatcttg
      661 gaaaaaatag aatgtatccc ttaacttatc tacttcgtca tctacactaa gaattatagg
      721 cttacttcct ctacttaaaa tatcattctc tatttttaaa taattcaaat agaatggatt
      781 gacggatgac aaattaggat ctcttttaca ttcaatttct acattatact ttcttcttat
      841 gatttctcta cattgttcat catttagtgc cttttctata ggtctacaca cttgtaatag
      901 ccaatgagaa atactctctt ctttagctgg aagaactgct ggttttaggt atatatagtt
      961 ggtaccattt agattagcat aatcatacgt attccctaat tcccattgct tagtaattat
     1021 atgtttgtac caattccatt tcgatagagg ttccatatct tcatataaac tattaaaagc
     1081 actaatggga gctctagaag gaccaatatc catttcatct gctagtctta ataaagctcc
     1141 caaatattta attttttcag gtaactttga gagttttata ctacggtgag cttctcctat
     1201 tgaaatgatt ttttgtatag tatctaagtc gaacccgatt tccgcaagaa aagatgattt
     1261 ttgttgtaaa aaagatttta taagattatg atgctttatt ctaatagcat tttctagctt
     1321 tgaaggatca tctaaatctg agctatcttt tttgagttca tctagagtaa aatcattcaa
     1381 agcagttaac atcccaacat catgtataca aatagcagca caaagcaaaa ataaatctct
     1441 attatctatt ttaattccgc cattaattaa aatggccaaa ttctcaaata tattgtctgt
     1501 atggactctt ccatgaattg taaaaaagtt aaatctagga ctgaattcgt gccatccatc
     1561 agatttattt ttaagcaatt ttaaaagctc taaatctctt tcaggaagtt tttggcatat
     1621 atctaacata atcacttagc ttagaaagta ctgataccag tatcagtttc tcatacaatt
     1681 atgtccagtt tatttcccca ttttttccca tgcccaaaca aacaaaaacc gcaatatact
     1741 catcacgaat atattgcggt ggaaaattga tggcggacag ggagggattc gaaccctcgg
     1801 taccggtttg cggtacacac actttccagg cgtgctcatt cgaccactct gacacctgcc
     1861 cgttggagat tgtgctagat aggaaagcag ggatagaata acggcagaag agaggtttgg
     1921 caatcttttt tttatccgga aggaattttc ccgttttccc cgagtttttt cacgtttccg
     1981 gcagctgctc gaaaaggatg aaaagcgccc cgacaacacg aggaagtctt caacaggcat
     2041 aagcagaaac gaagcgtatt ttcagaagtt ttgaaaggac aggtttccgt ggttcacaaa
     2101 aatcatccat gagggcatgg cagatttcct ccctccctgc cctgtttttc ccgcggagca
     2161 aacaagaatt tttctctttc tccacctttg cggcttccgg gcaatcgggc aaggttcagg
     2221 caagaacccc tattgataaa cttgcttccg tccagactca agaattgacc agcagacgtt
     2281 tgaggaattt caggagcgag acgggaagag aagactgaaa gattccggaa gcccagggtt
     2341 ccgagagttc cggaaaggcg cggcagaaat gggaatccac actgtaaaaa gagaaggcag
     2401 aacatgccgt ttcaccgcat atcatcattt ccgcggctcc gcattcctcc cgtcctcaaa
     2461 aaaggccaaa ggcttccggc atgtcccgga aaaggcgttt cccgaccgca cttccccctt
     2521 gacggatgcc ccaaagacag gtttgctagt cctgcgcatg ggagagtcct tttacacacg
     2581 caccacggag gccccctcct ccgcttttga tttgtccctc agaccacccg ctttcagcga
     2641 gttctgcggg caggagaaga ttaaggaccg cctgatgctg atggtggaag ccgccagaca
     2701 gcgcgacgac gtgctggatc acatcctgtt gagcggtccc ccgggcctgg ggaagacgac
     2761 gcttgccaat attatcgcga atgccgtcgg ctgccgcatt catacgactt ccggccccca
     2821 gattgaaaag gcgggagacc tggccggcgt gctgaccaat ctggaaaagg gggatattct
     2881 gtttattgac gagatccacc gcctgcaccc ggccattgag gagtatctgt acccggccat
     2941 ggaggatttc cggctggata ttatcatcga ccaggggccg aacgcccgct ccatccagct
     3001 caacctgccc aagttcaccc tggtgggggc cactacccgc gccgggatgc tgaccagccc
     3061 gctgcgttcc cgcttcggcc tggtgaaccg gctggattat tatacgcggg aggagctgtg
     3121 cgccattatc gaacggtccg cggggctgct gaacgtgccc gtggacccgg agggagccct
     3181 gcagattgcg ctgcgctccc gcggcacgcc ccgcgtggcc aattccctgc tgcgctgggt
     3241 gcgggattac gcccaggtgc gcggcgacgg cgtgattacg gagcagttgg cgcatgacgc
     3301 cctgaccatg attgagattg acgacgacgg cctggacgag atggacaagc gcctgctgga
     3361 agcgatgatt tacaagttca acggcggccc ggtgggcctt tcctccctgg cggtggccgt
     3421 aggggaggac gcttccacgc tggaggacgt gcacgagcct ttcctgatta tgcaggggta
     3481 tatcagccgc acccccaggg ggcgcgtggc gatgccttcc gcctatctca agatgggagc
     3541 cgcgccgccc gccaacggcc aggggtggct gttgtaggcc attcatttac ggcatggaag
     3601 gagtcctgcg ttttgtgctg gtcatcaggc ccgctttctt ttagactgtt tccacataaa
     3661 acgtcaggac gttttctgtt catcatacgc ccaaagctat ggccgcacat tctgatattt
     3721 cctttaaaag actgcccgtc aagattatcg gtacgggttc ctatgttccg gaacgccgcc
     3781 tgaccaatgc ggatctggaa aagatggtgg acacttccca cgaatggatt attgaacgca
     3841 cgggcattgt ggaacgccgc atcgccgccc ctgacgagta cacttcccat atggggacga
     3901 aggccgccca gcgcgctctg gaatcctgcg ggctgaagcc ggaggatatt gacctgatta
     3961 tcgtcgccac catcacgccg gatacgttca ccccttccac ttcctgctat atccaggatg
     4021 ccctgggcgc caagaatgcc gccgcctttg acatttccgc cgcctgctcc ggcttcctgt
     4081 tcgccatgaa gaccgccgtc cagtacatcg gcaccggcca gatgaagacg gcgctcatca
     4141 tcgccgcgga aaaactttcc accgtcgtca actgggagga ccgcagcact tgcgtcctgt
     4201 tcggggacgg cgccggagca gccgtgctcc aggcctccac aggggaagag ggggaaggct
     4261 ccgtccttgc cacggatatc ggttcggacg gctccctgca tgacctgctc cagattccgg
     4321 gcggcggctc ccgctgcccc accaccgcgg aaaacgccca tgaacgcctg gccaccctgg
     4381 ccatgcgcgg caatgagact ttccgccatg ccgtcacgcg catgaaagcc tccgccgcca
     4441 gcgtcattga acgcgccggc ctcacggcgg acgatattca gctgattatt ccccaccagg
     4501 ccaacctccg catcattaac gccgtagcgc agcgcctctc cattcctgaa gataaggtgt
     4561 tcgtgaacat tgagaagtac ggcaacacgt ccgcggccgc cgtcgccatc gcctttgacg
     4621 aagcgcgccg ttccggcaga ttcggcaagg gagacaatgt cgtcctggtc acgttcggcg
     4681 ccgggcttac ctggtccgcc gccgttatcc gctggtaata ttctttttca tactccccca
     4741 tcatcatgac cactgaacca tacggcaaaa aaaatccgtt tcccgctccc gtcctctccg
     4801 tcaagcacat caccggggaa ggcagtccca aggaaaccat ccacattgaa tacagcctgg
     4861 acggttccgg gatgaattac attgccgggg atgccctggc cgtcattccc gccaatgatc
     4921 cggccctggc ggacgctctg attgacaagc tcggcctcag cccggattcc caggttccca
     4981 cgccggaagg ggaaaccgca agcctgaagg acgctctggt tcactgctat gacattacca
     5041 atgtcaacaa agccctgctg accaaatggg ccgccgcctc cggcagccag gagctggacg
     5101 cgcttctggc cggggataaa gacgccctca acgatttcct gtggggccgg gacatgctgg
     5161 atctggccac ggaatatccc gcttccttca aatccgcgga agctttcacc ggcattctga
     5221 aaaagatcat gccgcgcctt tattccatcg cctccagccc gaacgcccat cccgaacagg
     5281 ttcacctgtg cgtgggcgcg gtgcgctata cggcccgtga ccgcaagcgc ggcggcgttt
     5341 gctccaccta tatggcggac cgcctccagc cgggccatac ggccagggta ttcgtacata
     5401 ccaacaagaa tttccgcctt ccggaagacg gggacacccc catcatcatg gtgggccccg
     5461 gcaccggcat cgcccctttc cgggcattct gggaggaacg cgccgcttcc ggcgccaagg
     5521 gcggcaactg gctgttcttc ggcaatccgt acagggccac cgacttctgt tatgaagacg
     5581 agctgaacca gttgaccggc accggcaaac tgaagttgtc cgtggcctgg tcccgcgacc
     5641 aggaaaagaa ggtgtatgtg cagcacctca tggtccagga aggcgaagag ctctggaaat
     5701 ggctggaagc cggcgcctgc ttctacgtct gcggggacgc ctcccgcatg gcgaaggacg
     5761 tggacaacgc ccttcatgaa gtcatccaga cctggggcca taaaactccg gaggaagccg
     5821 cggcatatgt ggcggacatg aaacagcacc gccgttacca gcgggacgtg tactaattcg
     5881 ggatctcccc cttgaacctg tcaccgcgcc tttccatctt ttctggaaag gcgctttttc
     5941 tttttccgga gaaaaaccgc cacgtatcaa tccagcttct ttcgagccgg agaagccatc
     6001 ttccgccccc ctctccatca aaaacaacgc cggaccggag agaacccgtc cgagcaaaag
     6061 ttcccctcct tcttcaagcg tttccttacc cttattccaa atcctgccgg gcgccgcaaa
     6121 cggcccgttt cactttccta agcttgaaaa agaagaccat gcaaaataaa tacagctttt
     6181 gcggcaaaca acgggctata cccctttttc ctggtccttt taaggaacca tctttgagaa
     6241 aaggaataat tccaccaatt ctgcaactga tcaatatagc ttatcttttt tctcctctcc
     6301 tctatttcag caagcaattc tttccgcgaa cgaaagacca gaacaaagct ctccagcaac
     6361 tcaccgcaca gtttcatccc cgcttctacg ctttctttca actgctccaa cattactaag
     6421 tccttccttt caaaagcctc tgccgtctgc atgtcggcaa accggaatgc gctactgaca
     6481 gcggagatat tttgtgctgc aaaacggtaa taacacagag ccgtatccgg caattcataa
     6541 atattaccct gcaaccatgc gtgaaatgcc attagatcat cctcaaaatt agccgttatc
     6601 ggaaaagcat ttccccactc gtatgcactt tttctgatga tcatagcagg tccataatga
     6661 gctgaagaag aaaaagcccc ttgttggagc acgacagccg gcatttcccg tggaacggag
     6721 ggaaatgccg ggaattcaaa cgcaactccc ggttcctcat agacgttaat catctggctg
     6781 actacagcca cagcatccgg atactccatc actgcccagg caaaaaacct gcatctccag
     6841 gggaaggaac aatcgtcccc atcctgacgg agaatccatt catgggaagc cagaccaacc
     6901 gcctgccgga tatgaggccc gcgccccagc ggcgtttcat tccggttcaa gattacccgg
     6961 tacggccccc tgtattgagc cgccatttcc tgcatgacgg cgaaggttcc gtcggaagat
     7021 ccgtcatccg aaaggatgat ttcaaccggc ccttcataat cctgcccgaa tacgctccgg
     7081 atggcatcct ggatgcaatg ctcctgatta tgcccggtca ggataatgct gatggaaggg
     7141 agtcgcgaag aattcatgaa aaaaagtgca gaaaaggaag tgaaaaaaac gaaaggaata
     7201 ttgctcttcc ccgtttacat ataagacatc atgttcatac cggattcgga attcgttatt
     7261 caagcacaag tacatacatt gaatcttgca tcattttatt aaaatactga ccatgaataa
     7321 attattatcc accctgattc tttcggtcgg catgagccta agcgctaccg cggctacctc
     7381 tctgctggat agctccatcg tgggatattc ggactttgcc tcccaaacgg cggatttcgg
     7441 caccctgaaa gattccgttt ccatcacgtc tgacgacagc aatctgacgt tatccgggat
     7501 aaccttcaac ggatacggtg ccaacaaccg cgacgttatg tctgtgacga tggttcttga
     7561 cctgtccaaa atcaacactc cggacgccta taccgctctg tttaacgcca aaaacagcag
     7621 tgtaagctgg ggcgtgggcc tgaacacgga ccggaaactc cagggattat ggaacaacac
     7681 ctcatacaac gggcccgtcg ttgacacccc gctgggcacg gaaggttccc tgaccatttc
     7741 cgtagtcacc ggagatcttg gcacccgcat ctattttggc gacagcgcta cgtactattc
     7801 caacagcggc ctgaaattcg gcaaccagca aattaatcag attctcatgg acgcaggact
     7861 ggctgaatcc atcgaacagc tctacatcca cgactccctt ctttcccagg aacaagttgg
     7921 tcaactgatg agtgaaatcg ccagcgttcc ggaacccgcc acggcctccc tgggcctgct
     7981 gggactggcc gcgctgatga tgcgccgccg cagggcataa gcctgtaccg tccgcctccc
     8041 tatattcaaa ggccggctca caaaatcgtg agtcggcctt ttccttatcc tctcaaacat
     8101 ctgccgaaaa aaacaggggg aagaagcttc catttgctgc ggcaacctca cggccagcac
     8161 ttgacgggga aatggcattc agtctccccc gggagggtca tttcaagagc ttccggcccc
     8221 gccccacttc cgtacacgcc cttttttccc atgccggaac agccggagcc gggccctgca
     8281 aagtccggat tccctctgca tccggaacag gccatcctct cagcaattca tttccccgca
     8341 cggtccggat cgctgcggtt tccgtccgtc ggcaacagac tccttccccg aaacagggaa
     8401 aaggagtggg aaaatggctg agcttgaacc tttatccccc gttcccgtcc atgaaccttc
     8461 aaaaacagca gctgctactg cgcctgttcc ggtatttcaa aagcagaaaa ggagaaccgc
     8521 gttttttcaa caaacggaat atatgccttc tggccgccgc cagcgcctac atcctgactc
     8581 ccgacgaatt cctgtttgac ggaatcggca agctgggcct tctagatgac gcggcggtca
     8641 tcctgggagc cgttctcacc gtcttttttc cggatggaga ctaacggccc gcacccaccg
     8701 caggcggaat tagcgggacg acactttccg gaacttcgga gactgtccca tgaatgtctc
     8761 cggattttcc aagagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgtagctc
     8821 gcaggccaga gccgtcagcg ccaggggatc ggaatccccc cagtctgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gtccggccca gtagccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccaacacgcg gcaaggatcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttcag cttgtcttcc aaatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatgg tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaataaa
     9241 ctccggaatg agcttcatca cctcccgtgc aaaggccacg tcttgagcct ctttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgccttc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccacggac gagcggtcgt aaccggccca
     9421 gaacgccggc tcccctaccg ccaggcagcc cgcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc gataaaagcc atgattccta tttgctgaag
     9541 ttcggggctc cgcaggctgc cttggccgcg gcggtttccg gcacggcgtc atccctgtaa
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa aaggggaaga
     9661 acctccatca gggcatggta gcggaaatcc gcctctccct ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcttttttac tccttttcat gcacagacga tacgcctgtg cggaaagcct cgtcaagccg
     9841 gaacaggtaa caaaataata actattccaa actgataaac agcaacgcct ttccacggct
     9901 tttcaaaaat ccgaaaagag ccggaaattc aagaagaggc ttgccatccg tgcctgaacc
     9961 gggcatcttg tggagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcattt tcggaggccc
    10141 tgaatggatc aacacctatg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 cattcgcgcg gggcttgggg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac aatgcggccc gcgaacccta cgtgttcaag aacaccatca aggcgacgct
    10321 ctcctcccgc tacatgattt acaccggcct gaccgtcctg gtgttcctgg tctaccacct
    10381 gtaccagtac accctgcgcg tgggatatga ccccgcccag ttcaccacct tcatttccga
    10441 cggcacggtg gaaacctttg acgtgtacaa aatgatcgtg gccggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccacctgc gccacggggt
    10561 gcagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggcccc tttacaactt
    10621 tgtcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggc atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaagctt gagtccaaac tgatcaatcc gaacaacaag cgcaaataca cggtgcttgt
    10861 ggtaggttcc ggcctggccg gcgcctccgc cgccgctacg ctcgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcatcaac gcggccaaga attaccagaa cgacggcgac tccgtttatc gcctgtttta
    11041 cgacaccgtc aagggcggcg acttccgcgc ccgtgaagcc aacgtttacc gcctggcgga
    11101 agtttcctcc aacatcattg accagtgcgt ggcccagggc gttccctttg gccgtgaata
    11161 cggcggcctg ctggataacc gctccttcgg cggcgcccag ctcaagcgca ccttctacgc
    11221 acgcgggcaa acgggccagc agctcctgct gggcgcttac caggccttgg aaaaggaagt
    11281 ggccaaagga cacattgaaa tgttctcccg ccacgaaatg atggatctgg tgctggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggtcacc ggtgaaatca agtcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggc tgcaacgtca ccgccgccta caaggcctac aagcgcggcg ctttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaagggcg actaccagtc
    11581 caagctgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcggaaaaaa tccgcaaaaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccatcaccgg
    11821 caagggcgtc ttcctagatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggtggcctgt gggtggacta
    12001 caacctcatg tccaatgtga aggggctgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaaa cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca ttatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gctaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gatggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ctggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa agcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgcc tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggctttggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 caggtttcct tgaaccagga ataaaatacc agacagttgc ttcctcatcg tcgcgcagcg
    13621 taaaaaattg ttacaccgga agggttccag taatccagga gaccgtactt ggaaatgccg
    13681 gacgaaacct aagcaagccc ccgtccgaca gcgacggccc ccatctttct tcgagagaaa
    13741 gaaacattga ttacaggaat tggactgatg cccggaaggg atggcctcct gtcaagggct
    13801 cagcatgaga ggaaaacatt ttctaacaaa cagacaacat tgatgtctat taagggaatg
    13861 cactga
//
