LOCUS       c00088_gnlPro..        15185 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AMIMDJPL_97.
ACCESSION   c00088_gnlPro..
VERSION     c00088_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 06:12:03
            Original ID  :: gnl|Prokka|AMIMDJPL_97
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15185
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15185
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[156:5185]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      157..5185
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..15185
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15185
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(157..1995)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-36, bitscore:
                     115.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNFEQFRCILITVNENVYNNFKKKAFTMAKMIEASVAMLKVIEAW
                     DVKQIYGYAGGSFNSTMHALDVEQERLQYVQVRHEQVGALAAAADAKLTGKIGVAFGSA
                     GPGAVNLLNGLYDAKEDHVPVLALVGQVAHTNMNYDYFQEFAEEPIFSDVAVFNRTVMT
                     PESLPYVVDKAIRTAYRENGVAVVTIPNDFGYVEIPDLNYDSASVPAKLTGIPTIDDEQ
                     VKTVLTMIKNAKYPVFHVGQGTRGATEDMMALAERLQVPIIITGLAKGVIPDSFDGNMG
                     SAYRAASKAADELMGITDLVVSVGADYSFAQIMYTTHDFKYVQIELDPGKFGRHHHLDF
                     GVNGDAKVFIKRALALSEPASPSPYYQAAKADMADWKQYLKKLSERTTDPLEYEQVYQE
                     INRVAADDAVFSMDVGDNTINSFRFLKMNPKQKLLTSALFATMGAGVPGAIAAKMSYPD
                     RQAFNIAGDGAFSMVMQDLLTEVKYHLPIFNIVTSNQTLNFIKSEQEDVPQPYYGIDLI
                     DADFAKIAEGMGVKGIRVEHFDQLHAAFETAMTELKAGRPVLIDAKITDKRGLPVEILD
                     VDPAKTSDASVSAFKEKYDANELKPLTSYFKEFNVE"
     CDS             2069..2542
                     /locus_tag="ctg88_2"
                     /transl_table=11
                     /translation="VLACRCSGKYRTLIHRLNLTNQQGEIMMKDKAINILTAELSALPV
                     LIMTYYALTAKPTGQWQLTFSLPVYWLISSDLLAYPWLLIRIPRLRHNPLKMNSLALKA
                     SSRYNCRLNERVARWDDEMNLAIFLLERGCLMLLSEPLLLGDLGYHSVRRLWY"
     CDS             complement(2601..3386)
                     /locus_tag="ctg88_3"
                     /transl_table=11
                     /translation="MTTNLFEDVVVRTTKFGDLPVLHVFAASQAQTKLPTIIDYHGWTN
                     QTATELGTAYQLVRAGFRVILPTAYLHGSRNDGTDLDRHPEHFWSIVGHSVAEFPQLVA
                     ALVAAGISDANKIGVMGTSMGGITAAGIMATQPTVVAGVSLIGSPEPVAFATDQVAQLP
                     AALQAKLPAELIEQTYQQLAKFDLSEHPEALAGRPMFFFNGTADQMVPYQYMRDFKHRF
                     KDEPALKATVFKRAEGGVHHVPHKIQEAAVAFLETNILK"
     CDS             complement(3550..3870)
                     /locus_tag="ctg88_4"
                     /transl_table=11
                     /translation="MATATLSDEEIRERIKTGKHMLFFTADWCPDCAFIKPVMPQIEAK
                     YDQYDWITVDRDANIEIAQDMGVMGIPSFVGIEDGQEIGRYVDKFRKTQKQVEDFLDTL
                     EK"
     CDS             complement(3942..4148)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_5"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 2.8e-24,
                     bitscore: 76.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNVISFAESLGGVESLLTVPAVQTHADLTEEQRQSKGITANLLRL
                     SVGIENSADLAADLKQALIRATK"
     CDS             complement(4145..5185)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_6"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 3.5e-95,
                     bitscore: 310.0, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNLGGNTRPASLEDGGFFCSHFYTGLSVDCPTITRLDGIEIMTKQ
                     AEKLHIETRLAQAGNRSDDEKTGAISAPIYLSTAYRHAGLGQSTGFDYPREAQPTRCIL
                     ERVLAEMEHGIAAYALTSGMAAIQLVFTLFNSGDKIIVSDDLYGGSYRFFDLLHDHYHL
                     DFAVWDGQDQATLAALADDQTVALWLETPSNPTMKVIDITATAATAHAHDLKLIVDNTF
                     YTPLIQKPLDLGADIVVHSATKYLAGHNDVLAGAVVVKSQADADALEFNLVTTGAVLDP
                     FDAWLLLRSLKTLPLRLHQQEANAQELVTVLEADEHVERVLYPGRGGMISFYLATGTDV
                     DTFYEH"
     CDS             complement(6091..6306)
                     /locus_tag="ctg88_7"
                     /transl_table=11
                     /translation="VAKDYQQTTANKQNFVFNQYQSGGLVYVEVYENTNADVAHLAGRF
                     RINAQGQLEQQQLAKGNVWQVVATQP"
     CDS             complement(6342..6635)
                     /locus_tag="ctg88_8"
                     /transl_table=11
                     /translation="LCQRLRLKKTRHLQQSRRSNRQLLNRRQLKHRQFPQLQLMSHNPK
                     LVQRLVRVVRQLLQLARRDIQIPLQLVKQLPGSLHPRPHHQLAASKRPIHSS"
     CDS             7194..7700
                     /locus_tag="ctg88_9"
                     /transl_table=11
                     /translation="MPRNLKEEVVFTAIMAGLMVFVMTAYNVTLAQGFSNGLVMAILSG
                     YPLGLFVAIILDLLVVGPIAKRLAFKYIINDYMRKRVVLIGITISVLMVLGMVTCMSLF
                     GIAVEGELSGSHVLATYGHTWIFNLIVALPLQLIIVGPIARGVLGKMQRATANTESAAA
                     MNEED"
     CDS             complement(8290..8739)
                     /locus_tag="ctg88_10"
                     /transl_table=11
                     /translation="MQRNVQAFIDDVTADKVTQDSLTGTYAKLATKVKPWLAKLVAALN
                     ADQLAQVTLTAKHEPAISFRLETSVINLPLANLTEIGKVTAAEDTLPINVYMIAESDAL
                     PSGLRIDELESVADVLADQANAEKLLTDWLTAQTDRLDQITAAEA"
     CDS             complement(8773..9153)
                     /locus_tag="ctg88_11"
                     /transl_table=11
                     /translation="LKLTRLVAFAFVSFFCYGIVNWMMSTSHFHLQAKNISVAEMWQGL
                     LIALVLYFLGVLAVYINRMLGFYVLGLVVLIYSLGLVSALMSGYQSTAGMEIKLALEVM
                     GVIGLGINFYTLVLLTRWRRAN"
     CDS             complement(9167..10180)
                     /locus_tag="ctg88_12"
                     /transl_table=11
                     /translation="MYYVAMKDHEIGRNLATEQYLMNNVDFDEPLVLFYYEEPCIIVGR
                     NQNTLEEINADYVREHHITVTRRLSGGGAVYQDLGNLCFSFVVDSDSQEFGDFKTFTKP
                     IIDALHDMGATTATVSGRNDLLVDGKKFSGNAMYSRNGKTFSHGTLMLNVDLNVVPQAL
                     TVPTDKIASKGIKSVRSRVTNLRPYLAPEYQNITVPEFQDALLKELFHVDSLDQIADKE
                     YHVTPEQQKAIDKIYEDYYANWDWVYGKSPEFSVKRRQHFDMGTIDARISVDDGLINNI
                     KFYGDFFGSGNVQDIEAALKGVRYDHEAIAKALADIDLNQYFTGIERSAVIDLIAQ"
     CDS             complement(10682..13054)
                     /locus_tag="ctg88_13"
                     /transl_table=11
                     /translation="LGILKLKIGMTKKVVTSLLLSTALLPMLSGKADTASANQKLAAAT
                     KGNSAASAASQQVTLSAGSQTETTAAGATDQSVASDGAKTDDQAESTSTTTATTSATSR
                     VTVRAASQAAKADSTGPQSQSSASEAAKDNAAASATADSTTSAVDQLDKTAKASAATSQ
                     ASHSTTNETAKASAAASQDSHVTTDQSSATVTSEVAKSAASSAAPKQATEQAVAAKISP
                     KIETAVAADAVQSSAMMARSTRAMTSQEIFLSQIKAGAISGWNKYQVLPSVTAAQAILE
                     SGWGQSQLATQGNNLFGIKGSYQGQSIYFPTQEWNGSQYITIQDAFRKYPNWSASVEDH
                     GAFLVVNPRYSNLIGVTDYRRVASLLQQDGYATAPTYASSLISIIEYNKLHEWDQEALS
                     GQASGGNDNNQVQPDQDVTPTSGTHKFTKTTTIHNAPDATSAVVGTYNAGETVNYNGKL
                     TVGNATWLRYQSYSGVSRYVMISQTTTNDNNNQATVTPASGSYKFTAKTNIRSAASKTA
                     QVVGTYNAGETVYYNGKITTGGTTWLRYLSYSGAQHYVAMSGDEVGAVAKPDVVATSGS
                     YRFTKTTAIKSSPATSATTVGSYNAGDTVYYNGKVTTNGQTWLRYMSYSGAQHYVQISG
                     ESTSTNVDKPQVTPQSGSYRFTQTTAIKNTPAGNAPSVGTYSAGDTVYYNAKVTANGQT
                     WLRYLSYLGAQHYVAISGNAATGNTTSKPVTNSQGAFRFVTTTNIRTAPSTRASVVGEY
                     NPGETVYYNGTVQAEGYTWLRYLSRSGATHYVAKLEG"
     CDS             complement(13519..13941)
                     /locus_tag="ctg88_14"
                     /transl_table=11
                     /translation="MKIIVSGHGNYASGLQSTIHLLAGDIANIEYIDFTDNMDDIQLSE
                     RFQRAVIGENNVVFMCDLLGGTPFKEAVKLSQVSEKDIAVTSGCNVGALLEVGFELTTY
                     SAPAKKLAEKLVKISQVQTKVFHHQAIQVDDGVEGI"
     CDS             complement(13943..14758)
                     /locus_tag="ctg88_15"
                     /transl_table=11
                     /translation="MASNSPISERGRLTKHDVRMLGWRSLFNQSAMNYERMQADGWTLA
                     MLPSLRKIYGNDKEGLAAALESNLQFINTNNYAAPLLMGLEASLEEHGEKRSTIDGLRI
                     ALFGPLAGIGDAITWFTILPIVAGITASFAKQGSILGPLVFFLVYLAMFVARAPIALLG
                     YNAGTKAISKIRENSGIVSHCASILGCTVIGGLIATYVQIAVKTKIPVSAGHTIAIQTQ
                     FFDRIFPNLLPLGYTFLLYWLLKKKNVSPVVLILGTFMLAILFSWMGVL"
ORIGIN
        1 cgctgagcat tggccgaaac gccttccagt cggcatagga cgcgcaccgg ctgacgaaca
       61 ggaatcgagt taaccggaac cttttaacaa tcattcctga cctatcctag aacgaaaaag
      121 cctgcaatca attgattgca ggctcgttca cactgactat tcgacgttga actccttgaa
      181 ataactggtt agtggtttca attcgttcgc gtcatatttt tctttgaagg cactgacaga
      241 agcatccgat gtcttggctg gatcaacatc aaggatttca actggtaacc cccgtttgtc
      301 cgtaatcttg gcatcaatta agaccggacg acctgccttt aattcggtca tcgcagtttc
      361 gaaggctgcg tgcagttgat caaaatgttc aacacggata cctttgacgc ccattccttc
      421 agctatctta gcaaaatcag catcaatcaa gtcgatacca taatatggtt gcggcacatc
      481 ttcttgttct gatttaataa agttcaacgt ttggttagac gtgacaatat taaagattgg
      541 caagtgatac ttaacttcgg tcaataagtc ttgcatgacc attgagaagg ccccgtcgcc
      601 agcaatgttg aaggcttgcc gatcaggata actcatcttc gccgcaatcg caccgggaac
      661 accggcaccc atcgtggcaa atagtgctga agtcaataat ttttgcttgg gattcatctt
      721 taggaaacgg aaactattaa tcgtattgtc gccaacatcc attgagaaaa ctgcatcatc
      781 ggcagcgacc cggttgattt cttggtagac ttgttcgtat tcaagtggat cggtcgtccg
      841 ttcactcagc ttcttcaaat actgtttcca gtcagccata tctgctttag ccgcttggta
      901 gtatggcgac ggtgacgctg gttcacttaa tgccaaggcc cgtttgatga agactttagc
      961 atcgccatta accccgaaat ccaaatgatg gtgccgacca aacttgccag gatccagttc
     1021 aatttgcaca tatttgaagt cgtgagtcgt gtacataatc tgtgcgaacg aataatctgc
     1081 gccaactgaa acgaccaaat cggtaatccc catcagttca tccgccgctt tcgaggctgc
     1141 ccgataagcg cttcccatat taccatcaaa actatcagga atgacgccct tggctaaccc
     1201 agtgataata atcggtactt gcagacgctc cgctaacgcc atcatgtcct cggttgcacc
     1261 acgcgtccct tgaccaacgt ggaagacggg gtacttggcg ttcttgatca tcgttaatac
     1321 cgtcttaact tgttcatcat caatagtagg aatgccggtc agtttagcag ggacacttgc
     1381 tgaatcgtaa ttaagatcag gaatttcaac atatccaaaa tcattaggaa ttgtcaccac
     1441 cgcaacccca ttttcacgat aagccgtccg aatggcctta tcgacgacgt atggtaagct
     1501 ttctggtgtc atgacggttc gattaaagac cgccacatca ctaaaaatcg gttcttcagc
     1561 gaattcttgg aaataatcat agttcatatt agtgtgagca acttgaccca ccaaggcaag
     1621 tacgggcacg tgatcttcct tagcatcata caacccgttg agtaaattaa cggcaccagg
     1681 accggccgat ccaaaggcga ccccgatttt acccgtcaac tttgcatccg ctgccgcagc
     1741 gagggccccc acttgttcgt gacgtacctg cacatattgg agccgttctt gctcaacatc
     1801 caacgcgtgc atggttgagt taaacgatcc accagcatag ccgtaaatct gtttaacatc
     1861 ccaagcttca ataactttta acattgcaac agacgcttca atcatctttg ccatagtaaa
     1921 tgccttcttt ttaaaattat tgtatacgtt ttcatttacg gttatcagaa tacatctaaa
     1981 ttgttcaaaa ttcaattgta aacaatcatt attttataaa tattttctta actaaccaaa
     2041 ttcgatgacc taacactggt ccgaaatcgt gttagcctgc cgttgttctg gaaaatatcg
     2101 aacgcttatc catcggctta atctaaccaa tcagcaaggt gaaataatga tgaaagataa
     2161 agcaattaat attctgactg ccgaactgtc agcactcccc gttttaataa tgacgtacta
     2221 tgcgcttacc gcgaaaccga ccggacagtg gcagctgacc tttagtctcc ccgtttattg
     2281 gctgatcagt tccgacctgc tagcctatcc ctggctcctc atccggattc cccgcttgcg
     2341 ccacaaccct ctcaaaatga attcactggc tctaaaggca agctcaagat acaactgccg
     2401 gctcaacgaa cgggtcgcgc gctgggatga tgagatgaat ctcgcgattt tcttactgga
     2461 acgcggttgt ctaatgttac tgtcagaacc actactttta ggcgatttag gctatcatag
     2521 tgtccgacgg ttatggtatt gatggcaata aaaagcaccc atgctgttca gttttatgaa
     2581 cagtgtgggt gctgtgtgca ttatttaaga atgttggtct ccaagaaggc gacagcagct
     2641 tcttgaatct tgtgaggtac gtggtgaacg ccaccttcag cgcgtttaaa gacagttgcc
     2701 ttcagggctg gctcatcttt aaaacggtgc ttaaaatcac gcatatactg ataaggtacc
     2761 atttgatcgg ccgtaccgtt gaaaaagaac attggtcgtc ccgccagtgc ttctgggtgt
     2821 tcagataagt caaactttgc caattgttga taagtttgtt caattagttc tgctgggagc
     2881 ttagcttgta atgccgctgg taattgtgca acttgatcgg ttgcaaaggc caccggttct
     2941 ggtgaaccaa ttaacgagac accagcaact accgtgggct gcgttgccat aataccggca
     3001 gcggtaatac cgcccatcga agttcccatg acaccgattt tattagcatc actaattcca
     3061 gcagccacta aggccgcgac taattgtgga aattccgcaa ctgaatgtcc aacaatcgac
     3121 caaaaatgtt caggatgccg atcgagatca gtcccatcat ttcgactgcc atgtaaatac
     3181 gctgtcggga gaatgactcg aaaacccgcg cgtactaact gataagccgt acccagttca
     3241 gtcgctgtct gatttgtcca accatgataa tcgatgatcg ttggtaattt agtttgtgct
     3301 tgactagctg caaacacgtg taatacgggc aaatcaccaa atttggtcgt ccgcaccacc
     3361 acatcttcaa ataaatttgt tgtcatgttt atcaccgttt ccaaaattaa tagttaatag
     3421 tgtagcagaa gcccaaacga aaaccaaccc aaacgcgtcc atcgtggtta aagcttaacc
     3481 atcatggacg cactcgagtt ggctcgtttt aacacggtta gttatcagct aacgtcatgc
     3541 ctttcaaaac tacttttcaa gtgtatctaa gaaatcttca acttgctttt gggtcttacg
     3601 gaatttgtca acatatcgac caatttcttg accatcttcg atcccaacga aactaggaat
     3661 ccccatcaca cccatgtctt gggcaatttc aatgttggcg tcacgatcaa ccgtgatcca
     3721 gtcatattga tcgtacttcg cttcgatttg gggcattact ggtttaataa aagcgcaatc
     3781 cgggcaccag tccgccgtaa agaataacat gtgtttaccc gtcttgatac gttcgcgaat
     3841 ttcttcgtcg cttaaagttg cagttgccat gaaaaatgcc tccaatatct ttataataat
     3901 tatagtttac cacatactaa aagtaagtaa agtcttttgc tttattttgt tgctcggatc
     3961 agcgcttgct tgagatccgc tgctaaatcg gcactatttt cgatcccaac ggatagccgc
     4021 aataagttag cggtgatccc ctttgattgt cgttgctctt ccgttaaatc tgcgtgtgtc
     4081 tgaactgccg gaactgttaa caggctctcg acaccgccaa gactttccgc aaacgagatt
     4141 acgttcaatg ctcgtaaaag gtatcgacgt cggtacccgt agcgagataa aaactaatca
     4201 ttccaccacg tcctggatat aagacacgtt caacgtgttc atctgcctca aggaccgtaa
     4261 cgagttcctg cgcattagcc tcctgctgat gcaaacgtaa tggcaaagtc ttcaagctcc
     4321 gtaagagcag ccaagcgtcg aacgggtcaa ggaccgcacc agtcgtcacc agattaaatt
     4381 caagcgcatc agcatccgcc tgcgacttga ctaccactgc accggctaaa acatcattat
     4441 gaccggctaa atacttagtt gcggaatgaa cgacgatgtc tgcgcctaga tccagtggct
     4501 tttgaatcaa cggtgtatag aaagtattat caacgattaa cttgaggtca tgggcgtgtg
     4561 cggtagccgc tgtggccgta atatctatga ccttcatggt tggattcgat ggcgtttcca
     4621 accacagggc aacggtttga tcgtctgcca gtgctgccaa tgtcgcttga tcctgcccat
     4681 cccagacagc aaaatccaaa tgataatggt cgtgtaagag gtcaaagaag cggtacgaac
     4741 ccccgtataa gtcatcagac acaataattt tgtcaccact attgaaaagc gtgaaaacga
     4801 gctggattgc cgccatgcca gaagtcagcg catacgcagc gatgccgtgt tccatctctg
     4861 ccagcactcg ttccaaaata cagcgggtcg gttgggcctc gcgcgggtag tcaaatcccg
     4921 tagattgtcc taaaccagca tgtcgatatg ctgtcgacaa gtagatgggc gccgaaattg
     4981 ccccggtctt ctcatcatca ctccgattac cagcttgtgc taaccgcgtt tcaatgtgta
     5041 atttctcagc ttgttttgtc ataatctcaa tcccatccaa tctagttatg gtcgggcagt
     5101 ctacagagag gccagtgtaa aaatgactac aaaaaaagcc gccatcttca agggacgccg
     5161 gtcgcgtgtt accacccaag ttcaattacg ggtcaccccg ttaaactcat caagtcatta
     5221 ttgactcact ggagtatcgg ccagtcccgc cagtacagcc ttgcgaccgc aactgggcat
     5281 tccgagttca tcttcatcag gcgctacctt accgctttac actccccacg gctccctgtc
     5341 aaaggtataa cctgactact cttctcatca acatgttatt taatgatatt ttcatcttac
     5401 tctcataata ataggagcgc aagccccaat cttatttcag cacaataaaa aatggtgcca
     5461 gcattatcct gaccaccatt tttacagaaa cgcattcgac actgcctagc tatcccaata
     5521 atttcaagac aatcacaaaa tatcctaaaa tcaaaatact caaccccagc gtcttcaaga
     5581 gggctaacca ctggccccct gcagttcgac ctttagggcc cagacaaatc gcaacgccgc
     5641 cacaaatcac ggccaaggtt cctagctcac ggccccagtt tgcattcaat aagtaaatga
     5701 acggtcccac taagccgctg acaatcgcga cgatccccag tattttcaga atcaagcggc
     5761 ccagtcgctt atcctgttcg tcataaattt catgtttctc ttttgccatc aaaccagcca
     5821 ccaatcttta tgaactactt tcagtatgcc gtatttggtc acaatgagca agaaggcggt
     5881 tacaatatcc tggtcaaatt actgaggcat cactaggcta gcttgtcata ccttaccttg
     5941 ggccctgccg gcacttaccc gtgataacag ctgaatcaag ctaccaaatt gaccatgatg
     6001 atactaaaaa ttaggtgttc aaaattgaca cccgctgaac acccaattgg caataactat
     6061 ttttcaattg taacctgcta aacgacgcca ttatggctgt gttgcaacaa cttgccatac
     6121 gttcccctta gccaactgct gttgttccaa ttgaccttgg gcgttaatcc gaaaacgacc
     6181 cgctaagtgt gcgacatcgg cgttggtatt ttcataaact tccacgtaaa ctaaaccacc
     6241 gctttgatac tgattaaaca caaagttttg cttattggcg gttgtttgtt gatagtcctt
     6301 agccacttgt tgccaagccc aatcattaat ctgactagct gttaactgct gtggattggt
     6361 cgtttgctgg ccgctagttg atgatgaggt cgcggatgca gactgcccgg tagttgtttg
     6421 actagttgca gtggtatttg aatgtccctg cgagctagct gcagtagctg tcttactacc
     6481 ctgactagtc gttgcactag cttcggattg tgactcatta gctgaagttg tggaaactga
     6541 cgatgcttta gttgacgacg atttagcagc tgtcgattgc ttcgtcgact ttgctgaaga
     6601 tgacgcgtct tttttagcct tagtctttga cacaactgat tgtgtttcac taacccgcga
     6661 ctgactagac tgatggtcgg cttctaagta ataaccgcct cccagcgcaa tgatcccagc
     6721 aatcacggct gaactaacta acattttttt caagataatc aactccccaa agattaattg
     6781 tctgatgcta actacagcat acgctatgtt gtctcacttt accaacgttt acctgttctg
     6841 gatcgaaatt taactttaaa ttatatttgg ctcagttggt ccatttttga gcacctaaga
     6901 ttcattgtgc catccttttc ttgactacgt atctcctcaa caacaaccgt ggcatcagca
     6961 gaaatgaatt ttgttaactt gaaagctgtt tccacaacct tatttcttta aagttcattt
     7021 tgccatcata ctgcccctta taagtatatc gtaaatgaca cccgactacg gcccaaaaca
     7081 ggctaacaat gtaaccgttt cataatttgt catcaaattg ttacttatgt gaggccccct
     7141 tcgcatgcta tagtaatcaa ccgatacaaa aaaactagga gtgtgtgaat agaatgccac
     7201 gtaatttaaa agaagaagtt gtctttaccg ccattatggc cggtttaatg gtctttgtga
     7261 tgaccgccta taacgttacc cttgctcaag gtttcagcaa cgggttagta atggcaatcc
     7321 ttagtggcta cccactcggt ttattcgttg ccatcatttt agacttattg gtcgtgggac
     7381 caattgccaa acgattagct ttcaaatata tcattaatga ttacatgcgc aaacgggttg
     7441 tcttgattgg gattaccatc tccgtcttga tggttcttgg catggtaact tgcatgtccc
     7501 tcttcgggat tgcagtggaa ggtgaattgt ccggaagtca cgttttagcg acttacggtc
     7561 acacttggat ctttaacttg attgttgcat taccactcca actcatcatc gtcggcccaa
     7621 tcgcccgcgg tgtgcttgga aaaatgcaac gggcaactgc taacaccgag tcagcagctg
     7681 caatgaacga agaggactaa tctttcagtc cattgacgga cggtcgccgg gataatctta
     7741 tcctgatggc cgtccgtttt attttacgac tatccagtcg accaccgctt ttgccgaata
     7801 gtccacccta tgaaagtctt atgcgtgatc tgtacgcaaa aaaaacgcgt gtcagccatc
     7861 cgaaaatggt taacacgcgt tcatcgcggc actggtaaaa ccagcgggag tgacactcca
     7921 caatgtcagt gacccagaca ctctgaaata cgtcagagaa acgtgccccg ctatcaatat
     7981 tagtcactag ccgctcgcgc ggaaccgtta ttgctaacga tctgactcta tcgactcatc
     8041 gcatggacta ccatatcatc ttcattgata aaatgcaagt cgcaccgcca caaaattcgt
     8101 ggctcctact caccacagtt gggccgcagt acttaacttt tcgcaaccaa aaaaattgag
     8161 tatcccgttc gatttaatga acgacacact caattccatt ggtattttga ttttggcttg
     8221 gctccaatat caattcttac cttaccatag tcatgtaaag atttagtaat taactcgtaa
     8281 agattacgtt taagcttccg ccgccgtgat ctggtctaag cgatcagtct gagccgtcag
     8341 ccaatcggtt aataactttt cagcgttggc ttgatcagcg agcacgtcgg caacgctttc
     8401 cagctcatca attcgcaatc ctgacggtaa cgcatcggat tctgcaatca tgtaaacgtt
     8461 gattggcagc gtatcctctg ccgccgtaac ctttccaatt tcggtcagat tagccagtgg
     8521 caaattaata acactcgtct ccaaccgaaa gctgatagct ggctcatgct tagccgtcag
     8581 cgtcacttgg gcaagctggt cggcattgag tgccgctacc agcttcgcca gccaaggctt
     8641 aaccttggtc gctagtttgg cataggtacc agtcaagcta tcctgcgtaa ccttgtcagc
     8701 cgtaacatca tcaataaaag cttgtacgtt tcgttgcata aaacattatc cctcattcat
     8761 tattcaattt cgttaatttg cacgtcgcca gcgagtcagt aacaccaacg tataaaagtt
     8821 gattcccaat ccaatcacac ccataacttc taacgccagt ttaatttcca tgccagccgt
     8881 actctgatag cccgacatta aggcgctgac aagtcctaag ctatatatca gtacaactaa
     8941 ccctaggacg taaaaaccca gcatacgatt aatatacact gctagaacgc ctagaaaata
     9001 taagactagg gcaatcagca acccctgcca catttccgct accgaaatat tttttgcctg
     9061 caggtgaaaa tggctagtcg acatcatcca attgacgata ccgtaacaaa aaaaggacac
     9121 aaacgcaaat gcaactaagc gagtcagttt caacaaatca ctcctattat tgggcaatta
     9181 agtcaataac ggctgaccgt tcaattcccg tgaagtactg atttaaatca atatctgcca
     9241 gcgctttagc gatggcctca tggtcgtacc gcacaccttt aagggcggct tcaatatctt
     9301 gaacgttgcc actaccaaag aaatcaccat aaaatttaat gttattgatc aagccgtcat
     9361 caaccgagat ccgcgcatca atggttccca tatcaaagtg ttgacgccgc ttaaccgaga
     9421 attccggtga tttaccgtaa acccaatccc aattagcata atagtcttcg taaattttat
     9481 caatagcttt ttgttgttca ggtgtcacgt gatattcctt atccgcaatc tgatccaacg
     9541 aatcaacatg gaacaactct tttaacaggg catcctgaaa ttctggcacc gtgatattct
     9601 gatattctgg cgctaaataa ggccgtaaat tcgtgacccg actccgaacg gacttaatac
     9661 ctttggaagc aatcttgtcg gtcgggactg ttagcgcctg tgggacaacg tttaaatcaa
     9721 cattcaacat caaagtgcca tgggagaacg tcttgccatt ccgtgaatac atggcgttac
     9781 cggagaattt cttaccatca acgagcaaat cattgcgacc actgaccgtc gctgtcgtcg
     9841 cccccatatc gtgaagcgca tcaatgattg gcttggtaaa tgtcttaaag tcgccaaact
     9901 cttgactgtc actatccacc acaaagctga agcagaggtt accaagatct tgatacacag
     9961 ccccaccacc agagagacgc cgcgttacgg taatgtgatg ttcccggaca tagtcggcat
    10021 taatttcttc aagggtgttc tggttccgac caacaatgat gcacggttct tcatagtaga
    10081 acaaaactaa tggttcatcg aaatccacgt tattcattaa atattgttcg gttgccaagt
    10141 tacggccaat ctcatgatct ttcattgcga cataatacat gttttaaaat ctccttcagc
    10201 tttaggttac tttaatcata cagcaagatg aaaaaaggac ccacaatgtg agcccatttt
    10261 ttggaagaat catacaaaaa gtttggcgtg gcattcttca caccacaaga tgactgattc
    10321 actatccaca tccgtgaacg tttgattggc ggcaatccgt tctccgtgga cataaccgtg
    10381 ccatcaatag atggaggttg ggccagtcag ttatccgaaa ttagcggaaa cgctgctata
    10441 ctgcactagc tatcacttga cgggtttgtt acaacaattg ggtaacagtt tgatactgac
    10501 ctgtgactct tccgataaat ccaatatagc atacaatgta agcgattgca aaccgagtaa
    10561 agaaacaacc tagtcagccg aagccaacta ggttgccgaa acattaatag cggtcgtaat
    10621 cgctattcca tttcaatatc cttagtataa agccatttgg acgccggaac aactaatatg
    10681 cctagccttc aagcttagca acatagtgcg ttgcaccgga gcgactcaga tatcggagcc
    10741 acgtgtaacc ctcagcttga accgtcccat tgtaataaac cgtttcacct gggttatatt
    10801 caccgacaac gcttgcgcgc gtacttggcg ccgtacgaat attagtcgtc gttacgaagc
    10861 ggaacgcccc ttgactgttt gttaccggct tagacgtcgt atttccggta gcggcattac
    10921 cactaatcgc tacgtaatgt tgggcgccca aataagacaa ataccgtaac caagtctggc
    10981 cgttagccgt taccttagcg ttgtagtaga ctgtatcacc agcactatag gtaccgacac
    11041 ttggggcatt tccggccggt gtattcttaa tcgccgttgt ttgcgtaaag cgataactac
    11101 cactttgagg cgttacttgc ggtttatcaa cattggtcga cgtactctca ccactaattt
    11161 gcacataatg ctgggcacct gagtaagaca tgtaacgtaa ccaagtctga ccatttgtcg
    11221 tcaccttacc attgtaatag accgtatcgc cagcattata agacccaacc gttgtcgcac
    11281 tagttgcagg tgaactcttg attgctgtcg ttttcgtgaa acgatacgac ccactggttg
    11341 caaccacgtc cggtttagcc acagcaccaa cctcatcacc actcatagcc acgtaatgct
    11401 gagcgcctga ataggataaa taccgtaacc aagttgtccc acccgtggta atcttgccat
    11461 tatagtaaac cgtctcacca gcattataag tgccgaccac ttgagccgtt ttgcttgcgg
    11521 ctgatcgaat gttggtcttt gcggtaaact tatacgaccc actagctggc gtaactgtcg
    11581 cctggttatt attatcatta gttgttgttt gactaatcat cacataccgt gatacgccag
    11641 aataggactg atagcgtaac caagttgcat taccgaccgt taacttacca ttgtaattga
    11701 ctgtttcacc agcgttgtaa gtacccacta cggcactcgt ggcgtccggc gcattgtgaa
    11761 ttgtcgttgt cttagtaaac ttatgtgtac cactggttgg ggtgacgtct tgatcaggct
    11821 gaacttggtt attatcattt ccgccacttg cctgaccact gagcgcttct tgatcccact
    11881 cgtgtagctt gttatattca atgatgctga tcagcgaact cgcgtacgtt ggcgcggttg
    11941 cgtagccgtc ttgttgcaag agactggcaa cgcgccgata atcggtaacc ccaattaaat
    12001 tgctgtaacg cggattgaca accaaaaagg cgccatgatc ttcaacacta gctgaccaat
    12061 tcgggtactt ccgaaaagcg tcttgaatcg taatgtattg tgagccattc cattcctggg
    12121 ttgggaagta gattgattgc ccttgataac ttcccttgat accgaataag ttgtttccct
    12181 gagttgcaag ttgtgattgt ccccaaccac tttccagaat tgcctgtgcg gctgtgactg
    12241 atggcaagac ttgatacttg ttccaaccag agattgcccc cgctttaatc tgactcagga
    12301 agatttcctg actagtcatt gcccgcgtgg accgtgccat catcgctgat gactggaccg
    12361 catcagccgc cacagccgtc tcaatctttg gtgagatttt cgcggctacc gcctgctcag
    12421 tcgcttgctt aggtgcggct gacgatgcgg ctgatttggc tacttcactc gtcacagtcg
    12481 cgctggattg gtccgtagtg acatgactat cctgacttgc ggccgcgctg gctttagccg
    12541 tctcattagt cgtactgtga ctggcttggc tcgtggctgc actagctttg gccgttttat
    12601 caagttgatc aacagcacta gttgtggagt ccgccgtagc actagcagcc gcgttatcct
    12661 tggcagcttc actggcggag gactggcttt gcggtcctgt actgtcagct ttagcggctt
    12721 gactggctgc ccgcactgtg acacgacttg ttgcactggt agtagccgtc gtcgtgctgg
    12781 tcgattcagc ttgatcgtca gtcttggcac cgtcactggc aactgattgg tcagtcgcac
    12841 cggccgctgt cgtttccgtc tgactgccag cacttaaggt cacttgttgg cttgcagctg
    12901 aagcagcgct gtttccctta gtcgcagctg ccagtttttg atttgcactt gccgtatcag
    12961 ctttaccact caacatcggc agcaaagcgg tacttagcaa taatgaagtt actacttttt
    13021 ttgtcattcc aattttcaat tttaaaatcc ccaaactttc cgtgagttag ctgttaacac
    13081 aaccgattta attcccctgt agcacctgct attacagaat aatattagca tgtcgaagag
    13141 ggacattcaa acgagatcgc ttcgaattat tttattaata tcaattgatt gacaccgtta
    13201 tcattttaaa ttattaacca attaccagtt agttatcatt attagtatcg ttacttgcct
    13261 aaatcccttg ataatattaa ctttgttaaa attaacttca cttttaaaca cttgaaacta
    13321 attaaagata gctggttatc caatagactt cactcacaat tgttaatttt aaaaaaacac
    13381 tctgtaacca aaaaagtcat aattctttat cttcatcaaa atatttataa tgtgcacttt
    13441 ttctattcaa aataacatat tccaaacaaa aaatccgatc aacagataac ttgttaatcg
    13501 gacaatctgt atatttcgct aaataccttc taccccatca tcaacttgaa tagcttgatg
    13561 atgaaaaact ttagtttgta cctggctgat tttaactaat ttttcagcca attttttagc
    13621 cggagctgaa tatgttgtaa gctcaaaacc cacttcaagc aatgcaccaa cattgcaacc
    13681 acttgtaacc gcaatatctt tttcactcac ttgacttaac ttaacagctt ccttgaatgg
    13741 cgtaccacct agtaaatcgc acataaagac aacattattc tcaccaatta cagcacgttg
    13801 aaatcgctca ctaagctgaa tatcatccat gttatcagta aaatctatat actcgatatt
    13861 ggcaatatca cctgctaaca aatgaattgt tgattgtagt ccacttgcat aatttccgtg
    13921 tccactaact attatcttca ttctaaagaa cccccatcca tgagaaaagg attgccaaca
    13981 taaatgttcc taatattaag actacgggac tcacattttt cttctttaat agccaataca
    14041 ataagaaggt ataccctaat ggcaataaat tagggaaaat ccgatcaaaa aattgtgttt
    14101 gaattgcaat cgtatgccct gctgaaactg gaatctttgt tttaaccgca atttgtacat
    14161 aagtagcaat taatccccca ataacagtgc accccagaat gctagcacaa tgtgatacga
    14221 ttcctgaatt ttcgcgaatt tttgaaatag cttttgtgcc ggcgttgtat cccaataatg
    14281 caattggcgc ccgtgctaca aacattgcta aatagactag gaaaaaaact aatgggccaa
    14341 gaatactgcc ctgtttagca aaagacgctg taattccagc aacaattggt aagattgtga
    14401 accatgtaat cgcgtccccg ataccagcca atggaccaaa caatgcaatt ctcagtccgt
    14461 caattgtcga tcttttttcg ccatgttctt caagagatgc ttctaaaccc atcaacagcg
    14521 gtgcagcata attattagtg ttaataaatt gcaagtttga ttcaagagca gcagctaggc
    14581 cctctttatc attaccataa atttttctta gtgatggcaa cattgccaat gtccaaccat
    14641 ctgcctgcat ccgttcatag ttcattgcag actgattaaa cagtgatcgc caaccaagca
    14701 ttcgtacatc atgcttcgtt aatctacctc gttctgatat tggtgaatta gatgccatcg
    14761 ccatcatctc cgtttccact ggcactttca atcattgatt taagtttttt ctcgttatcg
    14821 gtttgttttt tattgtgata aaactcaata aaagcaagtg aaatcccaat taccgcaacc
    14881 ggcatcaaat taccaaactt aataaagcac gccgctgtaa aaccaagtaa taaatatggg
    14941 acgtattcag cttttaacat acttttaagc aacaatccaa atccaactgc gggtaagata
    15001 ttacctgcaa tttcaaagcc atgacttaac cagacgggca tagaattaac caatgccttc
    15061 attggttctt gagcaccata aacacacaga aaagcaatca caccatatgt taatgcaaca
    15121 agtactgtag gtaacagcgc taatcttgtg aattttttag tttcaacatt cgccgcatat
    15181 gcatc
//
