LOCUS       gnlProkkaMBDPJAKP_1    14547 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBDPJAKP_1.
ACCESSION   gnlProkkaMBDPJAKP_1
VERSION     gnlProkkaMBDPJAKP_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 05:38:26
            Original ID  :: gnl|Prokka|MBDPJAKP_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2147186
            Orig. end    :: 2161733
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14547
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:9547]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9547
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14547
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14547
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="7"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(424..2304)
                     /locus_tag="ctg1_2273"
                     /transl_table=11
                     /translation="MAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFIPENMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNIS
                     REMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANK
                     DQLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKYIYYATGDSYDRIEKLPQTEMVADKGY
                     EILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEENKYKDLFKEMN
                     NILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHE
                     VFQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     CDS             complement(2472..2723)
                     /locus_tag="ctg1_2274"
                     /transl_table=11
                     /translation="MKVQHKKELKFYCFITIPSAFVVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG"
     CDS             2826..3026
                     /locus_tag="ctg1_2275"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIEQATAEVFANEGARVMIGDINTDQMEE
                     TVDAIRKKRRTGRILSPRCVR"
     CDS             2965..3648
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     183.3; E-value: 9.1e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2276"
                     /transl_table=11
                     /translation="MTQSEKNGGQAESFHLDVSDENSVKAFADQIKDACGTIDILFNNA
                     GVDQEGGKVHEYPVDLFDRIIAVDLRGTFLCSKYLIPLMLDNGGSIINTSSMSGRAADL
                     DRSGYNAAKGGITNLTKAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEAFR
                     EANKWVTPLGRLGQPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKW
                     KEETK"
     CDS             3915..4115
                     /locus_tag="ctg1_2277"
                     /transl_table=11
                     /translation="MNNKVKIERLTLGLTQADLAKKLGITRQTVSLIEKGHYNPSLNLC
                     IRICNVFKKTLDDVFWPSDNL"
     CDS             4133..4534
                     /locus_tag="ctg1_2278"
                     /transl_table=11
                     /translation="MIDERIQQEQHKLSYYSFGLSIILFILSFFVSILTQNLFYTQLSI
                     IISFMVVSTYYSIFAIKRGLIIKRKNSNLKHFYIFILSGMFWIIISFLSKEINNMKELL
                     IQLLFFSLFYTVIFLSIRSIIKYSHKQSN"
     CDS             complement(4738..4956)
                     /locus_tag="ctg1_2279"
                     /transl_table=11
                     /translation="MLHNIENSNKMIELSEQEMLNTDGGGWRDLAGAAAGAAVMGGTAI
                     ALGAAAGPVGFAAGVGMAILTRPGHAR"
     CDS             complement(5001..5222)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2280"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.5e-08,
                     bitscore: 32.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQNTNFELLTVEEAEKIDGGGYGSYLIRGVGTGTAVGAALGGP
                     GGAVLGANVGAIWGSAAYGVDALISGHK"
     CDS             5544..6668
                     /locus_tag="ctg1_2281"
                     /transl_table=11
                     /translation="MDKFTRKTSFEQWFSPIFSTKLEELVESYQLNYYTKKLHIASFLK
                     LFVFAQLNETESLRAVSETLFSDDLQKATHLEAISFSQLGRRLNQVPTEVFQQVFLDLV
                     AQIHEKSHYEQRRETTTPLKIIDSSTLPLNLKNHKWAEFRKTKSGIKLHLRLVYAEKGC
                     SYPDKAVLTNAKEHDRGQLEVLVDDKECMYVFDRGYLDYERFDRMTDDGYFFVSRLRKN
                     AVIRVIEPFKLPEDSLVFSDEMVLIGTPQNRAENAFRLIKVLDSKGNELHLITNRFDLS
                     ADEIAELYKSRWAIELFFKWLKQHLNIKKFYAQSEQGVHNQVYIAMIVYCLNVLAQLNT
                     NSSRTYLQISRLLKAAPWKSAHLWLRKIVGKTVP"
     CDS             6946..7200
                     /locus_tag="ctg1_2282"
                     /transl_table=11
                     /translation="MEFLYILVESVIWILITTIPSKRNLKFRRNLKTLKKHAWFRNLMK
                     DYRPLFLMNSTIQNKIIEYNENIDSKTFKMELEQLAKNI"
     CDS             7364..9547
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     248.8; E-value: 6.5e-76)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 300.9; E-value:
                     3.1e-91)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2283"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.8e-43, bitscore:
                     144.5, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 1.1e-235, bitscore:
                     782.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILKKYHCVKQMDDKDCGAACLATILKHYGSKISLAKIRNIAGTD
                     TQGTNVLGVIKAAETLGFSAKGVKADQTAFEQPFPLPAIAHVVLNGQLLHYMVIHKIKK
                     DKIIIADPGKGIITYRKDEFFKIWTGILIFMVPSDTYQQQTDIRSVKKDILNLILHQKS
                     LIIHTALASFIITIFGILSTFYFQTIIDQILPNGLKNSLHIISIGLIIMYLFKVLLTAF
                     RQYLMILLGQKLSISIMLGYFKHVLKLPMKFFSTRKDGEILARFNDTNKVIDAIVSASL
                     SAVLDTFMLIMVGIFLYIQNTSLFIVTLALIPFYILTVWVFMKPYESINDNEMENNAQL
                     TSKIVETLSSIETIKAYNAEYIMSFETEKRFVKYLQSSFKHGVIDNLQSSIKLFLDLIS
                     GALILWIGAWQVIKGNMTIGQLITYNALLAYFLNPLQNIISLQSKLQSASVASKRLGEI
                     LDEEPEIQTSEARVTDPAYIQGPIEINNVDFRYGTRRLILKDITLHIQKGEKVAFVGES
                     GSGKSTLTKLLMKFYTAESGEILINGYHINDIHTNALRESISYIPQESHFIQGSILENL
                     LLGNSGSFTFEEIIEVCKQTNVHDFVNDLPMRYDTLVEENGSNLSGGQKQRLAIARALL
                     RKPNILIMDESTSNLDTTTEQGISKMIYAQTVDVTTIIIAHRLSTIMNCDKIFVMENGE
                     IIEYGNHNDLLKKKGKYYELWENQMPSREMVTI"
     CDS             9548..11017
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 77.5; E-value:
                     1.5e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2284"
                     /transl_table=11
                     /translation="MKRNFFNLHDLKDSREFYESKPKPIGVFFTYILIALLIACIVFSF
                     YGKKEVILKTAADIQYTKPNSNVTNEVAGKVKTVDIKQVDKVKKGDTLLTLDNTEIQAQ
                     KKAVKADIKDVKEQAALNKTLKKSIENDKNLFSEDDHWGYQDQYLSYEKQSNLLESSKE
                     NAKTQQKKLKKQKKSIKNSLDKTKNKVKRKLQRISDLQDSIKNNKSFAKQDDKYSSYYN
                     SFQTNKQNVEQQLDDLRKMKDELDKNSFSQKKENLNGQLESLKQDMLVKLSEEKDELNQ
                     SFDEINSSMKSDDSDSDSDNSEETNYKLSIEQLKTNLLNQTSQKQTDLQTTLKSKEDDL
                     KMIDLQLEKYKIKATSDGYVNVLTNISPGDYLQAGTAILTIVPDKEKLKANIYIPSHEI
                     TNINEKDEVRFHIENTNQTVKGVITKISPDSISDQSGQKFYIAESTIESKEIEKNNGTK
                     IHLKNGMQTDVSIIVDSKRYIDYFLDVLHLR"
     CDS             11119..11307
                     /locus_tag="ctg1_2285"
                     /transl_table=11
                     /translation="MSQNKLLFLLFLFSSIVRLFFNTVLSPTVSWKSWTVNIVFILLFL
                     LFLNLTLKERKSKDQVL"
     CDS             complement(11426..12460)
                     /locus_tag="ctg1_2286"
                     /transl_table=11
                     /translation="MKTLCTHSLPKEKMPYLLRSGEGERYLFGRQVATVMANGRSTGDL
                     FEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLLISGDYANIPAGTPHS
                     YRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVSNERFAEAAAVADIVF
                     LDEGKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRIVAAQKNTDGQFIVVS
                     SEGPKGDRIVDHYHEHHTETFYCLEGQMTMWADGQEIQLNPGDFLHVPANTVHSYRLDS
                     HYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALHFDRVLQNIEALDLKVDYRADI
                     VSAR"
     CDS             complement(12554..13129)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 64.7; E-value: 2.4e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2287"
                     /transl_table=11
                     /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYH
                     FFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPTEAIQLFIKKTASQFDNTESIKGI
                     PVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFADEEANQLGTLINSMIEGG
                     IMLSLTNKDKTPLLLIAEQIPVLVRKKG"
     CDS             13260..14330
                     /NRPS_PKS="Domain: PKS_KR (32-194). E-value: 5.4e-10.
                     Score: 31.3. Matches aSDomain:
                     nrpspksdomains_ctg1_2288_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     181.7; E-value: 2.8e-55)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2288"
                     /sec_met_domain="adh_short (E-value: 2.2e-30, bitscore:
                     104.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIDHSVTNTEQLERQNPAIKTKLKLKKLKDQVIVITGASSGIGL
                     VTARMAAEKGAKVVAAARNEDALKELTDELKEKGHDAIWVKADVGKEEDVNRIAETAIS
                     TFGRFDTWVNNAAVSTFGHAMDVTVEDMKRMFDTNFWGPVYGTRAAVKHYTGRGVPGAL
                     INVGSLFGDRGTVIQSTYASAKFALHGWTESIRMELEKEQAPVSVTLIHPGRIDTPYNE
                     HAHSYLDKQPAHYRSMIYPPEAVAEAILFAAEHPKRDMYIGSQAKAIAMLGALFPRLTD
                     RLMEKIMYHSQHAEKPSKPREESALYDAGCGMHDRGTNKGWMRSRSYYTNATKRPIVSA
                     AVVAGLVAWAAAKRCR"
     aSDomain        13356..13841
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2288_PKS_KR.1"
                     /evalue="5.40E-10"
                     /label="ctg1_2288_PKS_KR.1"
                     /locus_tag="ctg1_2288"
                     /protein_end="194"
                     /protein_start="32"
                     /score="31.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VIVITGASSGIGLVTARMAAEKGAKVVAAARNEDALKELTDELKE
                     KGHDAIWVKADVGKEEDVNRIAETAISTFGRFDTWVNNAAVSTFGHAMDVTVEDMKRMF
                     DTNFWGPVYGTRAAVKHYTGRGVPGALINVGSLFGDRGTVIQSTYASAKFALHGWTES"
     CDS_motif       13359..13436
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2288_0001"
                     /evalue="1.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_2288"
                     /protein_end="59"
                     /protein_start="33"
                     /score="17.8"
                     /tool="antismash"
                     /translation="IVITGASSGIGLVTARMAAEKGAKVV"
ORIGIN
        1 tcaacagcgt ggatgacagt agtctttcta ggtgtctata tcgtctttta ccaggcgaca
       61 tggggtccgg tagtgtgggt gctcatgcct gagctcttcc catccaaagc acgcggagcc
      121 gcgacagggt tcacgacttt ggtgttatcg gcggctaacc tgatcgtgtc gcttgtcttc
      181 ccgctgatgc taagcgcgat gggcatcgca tgggtcttta tggttttctc agtcatttgt
      241 cttctctcat ttttcttcgc gttctacatg gtaccggaaa ccaaagggaa aagcttggag
      301 gaaattgaag caagcctgaa aaaacggttt aaaaagaaga aaagcaccca aaaccaagtg
      361 ctgaatgagc gtactttata aaaaaaagga atcgtctcct taagggacga ttcctttttc
      421 tgtttacacc atgaccttgc aaatattgtt cgtaaattca acagggtcct gaatcggcag
      481 gccttcaatg agaagcgcct gattgtacag aaggtttgtg tacaggctca gcttctcttt
      541 atcttgttca aacgcgtcct gcagcgtttg gaatacctcg tgattcgggt tgatttccag
      601 cactttttcc gccttcacat tttggctgtc aggcattgcg tttaagattt tttccatctc
      661 aattgtcact tcgccgtcag cagcaaggca gactggatgt gatttaagcc gttttgagat
      721 tctgacgttt ttcactttgt ctgacagaat gttattcatt tccttaaaca gatccttata
      781 cttgttttcc tcttcctcgg actgcttttg atcctcatcc gtgtctatgc caaggtctcc
      841 gcttgatacg gacttgaatt ctttttcctg ataagaagcc agcattttaa ttgcaaactc
      901 atcgatgtcc tcagtaaagt agaggatttc atagcctttg tccgccacca tttccgtttg
      961 cggcagtttc tcaatgcggt cgtaagaatc accggtcgcg taataaatgt atttttgctc
     1021 ctctggcatt ctggaaacat actcgtctaa gctgaccagt tttttctctt ttgaagagta
     1081 gaataatagg agatccttca attgatcctt attcgcgcca aaatcattat acacgccgaa
     1141 tttcagctgt ctgccaaacg acttgtagaa cgtctcgtat ttctcgcggt cttttttcaa
     1201 caggctttgc agctcgcttt tgattttctt gctgatgttt ttcgcgatca gcttcagctg
     1261 gcggtcatgc tgcagcattt ctctggaaat attcagcgac agatcctcgg aatcgaccat
     1321 gcccttcaca aagctgaagt ggtccggtag caggtctgcg cacttattca tgatcagcac
     1381 gccattggaa tacagctcca agcctttctc atattccttg gaatagtagt caaacggcat
     1441 gttttcaggg atgaatagaa tcgcgttgta gcgaaccgct ccatccacac tgatatgaac
     1501 gtgtgtcagc ggtttatcaa acccgtaatg cttttcagca tagaattttt cataatcctc
     1561 atctgtcagc tcgcttttgt tttttctcca gatcggcacc atgctgttga ccgtctgctc
     1621 ttcctgcacc tcttcgaatt cattttcgct gccttccttc ggcttattaa tggtcgtatc
     1681 cattttgatc gggtagcgaa tgaagtcgga gtacttcttg atgatcgctt ttaaacgata
     1741 ttcttctaag aattcgtcat agctgtcatc ttctgtgttc tctttgattt tcaggataat
     1801 gtctgtaccg acagaatcct tttcacacgg ctcaattgta tagccgtctg cacccgcaga
     1861 ctcccattta taagcctctt cgctgccaag cgctttactg atgactgtca cgacatcggc
     1921 aaccataaat gccgcgtaaa aaccgacacc gaactgcccg ataatgtcat gtccgtcttt
     1981 cagctcgttt tcctttttaa acgcgaggga accgcttttt gcaattgttc caagatgctg
     2041 ttcaagctca tcctttgtca ttccgatccc cgtatcagag atggttaatg ttctcgcatc
     2101 tttgtcagct gcgaccttta tgtagtaact gtctttatca aacgtaagcg catcgtccgt
     2161 aagcgctttg taatagattt tgtcaatcgc atcactcgaa ttggagatta actcgcgcag
     2221 gaaaatttct ttttgggtat aaatggagtt aatcatcata tccagcaagc gtttagactc
     2281 tgctttaaac tcttttttcg ccactcttga tcgctccttt accattatgt aaaccctttt
     2341 tagcatctat ttatcacata agatgacaat tgtcaattag attgatagat gcatatatat
     2401 gtaaatttaa cattagttgg atttgttttc actctttttc tcactcattc tcataaaaaa
     2461 gagaggcttc atcatcctct ctttttttct gtgtcattcc agcggccaaa ctcccgcttc
     2521 atccatatat gcaccgggta gaaaaacaaa ccgaacggta tcaaaaacaa aagattatgc
     2581 catgaagcat tcagaaatgc gcttgcagtc accggaaacg taatctcttg caataaaaaa
     2641 gagatgacag tcagcacaac aaacgccgat ggaatcgtga taaagcaata aaacttgagc
     2701 tccttcttat gctgtacttt caaaacacac aaccctccca acaatttccc aatccatctt
     2761 aacatatgtt ggcagttctt tttcttcatg tttatcactg ccaaatagaa aaaggaggtc
     2821 tcgtcatggg aagacttgaa aacaaaaccg cagtgatcac aggcgccgcg acaggcattg
     2881 aacaagcgac ggcagaggtt tttgccaatg aaggcgcgcg tgtaatgatc ggagacatca
     2941 atacagatca aatggaagaa acagttgacg caatcagaaa aaaacggagg acaggccgaa
     3001 tcctttcacc tcgatgtgtc agatgaaaac agtgtgaaag cttttgctga ccaaatcaag
     3061 gatgcatgcg gaacgattga tattctgttt aataatgccg gcgttgatca ggagggcgga
     3121 aaggtgcacg aatatccggt tgacctgttt gaccgcatta tcgccgtcga cctgcgcggc
     3181 acgttccttt gcagcaaata tctgattccg ctcatgctcg acaatggagg ttctatcatc
     3241 aacacctcct ccatgtcagg ccgcgccgcg gatcttgacc gctccggcta taacgcggca
     3301 aaaggcggta tcaccaacct gacaaaggca atggcaatcg actacgcacg gaacggcatc
     3361 cgcgtcaatt ccatttcacc aggtacgatc gaaaccccgc tgattgacaa attagcaggc
     3421 accaaagaac aggaaatggg cgaagcattc cgcgaagcca acaaatgggt cacgccgctc
     3481 ggccgccttg gccagccgaa ggaaatggcg acagtagcgc tgttcctcgc gtcagacgac
     3541 agctcatacg tcacaggaga ggacatcacc gcagacggcg gcatcatggc atatacatgg
     3601 cctgggaaga tgctgattga tgagaaatgg aaggaagaaa cgaaataacg ttagctcaaa
     3661 gagggataaa acgccctctt tttttaattt ccgaatgcaa acgaaacaaa aaaaacactc
     3721 ctatttatga cttttttcaa tctaaaacct tgaacattga atattagtca ggctccgact
     3781 atctcagtaa tatgtttcat ttaagaatat ctccaaaaga ctcctttcag ttttaacaat
     3841 ttcatcctat caatgtaata tatattgtac ataaagtaat atatatgtta cgatcattaa
     3901 taaaggagga tgccatgaat aataaggtta aaattgaaag attaactctt ggtttaactc
     3961 aggctgattt agctaaaaaa cttgggataa caagacaaac tgttagctta atagaaaaag
     4021 gtcattacaa tcctagttta aatttatgta taagaatttg taacgttttt aaaaaaactt
     4081 tagatgatgt tttttggcct tcagataatt tatagaggag tgcatagtta gaatgattga
     4141 tgaaagaata cagcaggaac aacataaact gagttattac agttttggtc tgtctataat
     4201 tttatttatt cttagttttt ttgtttctat tctaacccag aacttatttt acacccagtt
     4261 aagtataatt atatcgttta tggttgttag cacttattat tcaatttttg ctataaaaag
     4321 gggcttaata ataaagagaa aaaacagcaa tttaaaacac ttttatattt ttatactgag
     4381 cggaatgttt tggataataa taagttttct ttctaaagaa ataaataata tgaaagaatt
     4441 actgattcag ttactatttt tttcactctt ctacactgtt atatttctaa gcatccgttc
     4501 tataattaag tattcacata aacaatctaa ttagtacata atttaaatta ggttataacc
     4561 ttttaaggaa agtgtttaac actaatagta ataggagtat attaacctac agattttttc
     4621 aaagtattaa cataacccct cactacaaaa ctgttggtaa aggtatgaag ttgagccctc
     4681 aaataattgt aaaagaaaaa gctgtcgtca tttatcgaca gctttctata agataagtta
     4741 tctagcatga cctgggcgag ttaagattgc cattcctact cctgcagcaa atccaactgg
     4801 cccagcagcc gctcctaaag caatggccgt tccacccatt actgcagctc ctgcggcagc
     4861 tcctgctaaa tctctccacc ctcctccgtc agtatttaac atttcttgtt cactcaattc
     4921 aatcatttta ttactatttt cgatattatg taacatgcta aacctcctgt ttttttacgt
     4981 ttatattagt gaaattttaa ttacttatgt ccagaaatca atgcatctac accgtacgct
     5041 gcagaacccc agatagcccc aacgttagca cctaaaacag ctccgccagg cccgcctaaa
     5101 gctgctccca cagcagtgcc tgttccaact cctcttatta aataagaacc ataaccccca
     5161 ccatctatct tttcagcttc ttctacagtt aataattcaa aattggtgtt ttgctttttc
     5221 atagtttact cctcctaagt ccgaacttgg taaattattg tcgacttata ttactataaa
     5281 tgtaatttga agttttttca acagttataa ccaaatttat attacttaat acatctaaaa
     5341 tgcctataat ttctttaatt acttaatatc ctagagtcgc tatgtaattg aatatttgac
     5401 taaattccac tagtgtcgca ttaaaataat tcaacgattt ataaaaatct aaattttcag
     5461 taattttatc tttgcataaa aaaagccttt ataatggtag ggcggtaata aaccatccaa
     5521 atccaaagta aaggacaata agcatggata agtttacacg aaaaacatca tttgaacaat
     5581 ggttttcacc gattttctcc acaaaactcg aggaattagt tgaaagctat caattaaatt
     5641 actatacaaa gaagctacat attgcgtcat tcttgaaatt gttcgtattc gctcagctca
     5701 atgaaaccga gagtctgcgt gcagtcagtg agacattatt ttctgacgac cttcaaaaag
     5761 cgacgcattt agaagcgatt agcttttcgc agctcggacg ccgattaaat caagtgccga
     5821 ctgaagtgtt ccaacaggta tttttggatt tagttgccca aattcacgag aaatcacatt
     5881 atgagcagcg ccgagaaacg acaacaccac tgaaaattat cgactcgagt acgttgccat
     5941 tgaacttgaa aaaccataag tgggctgaat tccgtaaaac aaagtcgggc atcaagcttc
     6001 atttacgtct tgtttacgca gaaaaaggct gttcctatcc agataaagcg gtgctgacaa
     6061 acgcgaaaga acatgatcgt ggtcagctgg aagtactcgt tgacgacaaa gaatgcatgt
     6121 acgtctttga ccggggttac ttggattatg aacgatttga ccgcatgaca gacgatgggt
     6181 atttctttgt gtcacgctta cgaaaaaacg ctgtcattcg tgtaatcgag ccatttaaac
     6241 tgcctgaaga ctcgcttgtg ttttcagatg aaatggtttt gattggtaca ccacaaaacc
     6301 gtgcagaaaa cgcttttcgc ctcatcaaag tgctcgattc aaaaggaaac gaactgcatc
     6361 tgatcacgaa tcgatttgat ttaagcgctg acgaaatcgc tgagttatat aagtcgcgct
     6421 gggcaatcga gctatttttt aaatggctga agcagcacct gaacatcaaa aagttctacg
     6481 cgcagagcga acaaggcgta cataatcaag tgtatatcgc aatgattgta tattgcctaa
     6541 atgtactggc acagctgaac acgaacagtt caaggacgta cttacaaatt agtcgcttac
     6601 tcaaagcggc accatggaaa tccgctcatt tatggctacg aaaaatcgta gggaaaaccg
     6661 tgccctaaag aatttcacag gtctgttgca ctcgtcaaag attatagtaa aaaaatggat
     6721 gttaactacc tctattcaaa tgtctttgtt tttcttctca tgagcaaaaa caagaaagca
     6781 gaaaattcag tcaaaattta tgcaacacta gtgactaaat tcatataata actaactact
     6841 tgaaacttta accaaagttt tttttatgtt aatctagaaa aggatttttt atgaaaaatt
     6901 aattttaata tcataatgtt ttattagcat aaggaggtta atttgatgga gtttttgtac
     6961 atattagttg agagtgtgat atggatttta attactacca taccatcaaa aagaaacttg
     7021 aaatttagaa gaaacttaaa aacattaaaa aaacatgctt ggtttcgcaa tttaatgaaa
     7081 gattacaggc ccctgttttt aatgaactca actatccaga acaaaattat tgaatataac
     7141 gaaaatattg attctaaaac ttttaagatg gagttagaac aactagcaaa aaacatataa
     7201 gtgtgaaaag tatgtacaat taataatcta aatttcatcg tacctttaca caaaaaagtt
     7261 atatttcacc ttaaattatc gatatatgta ttactgttat attatgatta taaagttccg
     7321 cataatttta cggattaaat tttttaacta cggagattag aaaatgattt taaaaaaata
     7381 tcactgtgta aaacaaatgg atgataaaga ttgcggtgct gcgtgtttag caacgattct
     7441 aaagcactat ggatcaaaga tatcactagc gaaaattcga aatattgctg gcacagatac
     7501 acaaggtact aatgttcttg gtgtaataaa agcagcagag acccttgggt tttctgcaaa
     7561 aggagttaaa gctgatcaaa cagctttcga acaaccgttc cctcttccag ctattgcaca
     7621 tgtggtttta aatggtcaat tattgcatta catggtcata cacaaaatta aaaaagataa
     7681 aattattatt gctgatccag gaaaaggtat aatcacctat aggaaagatg aattttttaa
     7741 gatttggacc ggaattttaa tttttatggt tccaagtgat acttatcagc aacaaacaga
     7801 cattagaagt gttaaaaaag acattttaaa tttaatactt catcaaaaat ctttaattat
     7861 acatacagca ttagcatctt ttattattac gatcttcggt attctgagca ctttttattt
     7921 tcagacaatc attgatcaaa ttttgcccaa cggtttgaag aactctttac atattatttc
     7981 tattggactt ataataatgt acctatttaa ggttctttta acagctttta gacaatattt
     8041 aatgattcta ttaggtcaaa aattaagtat atccattatg ctgggttact ttaagcatgt
     8101 tcttaagctg cctatgaaat tctttagcac tagaaaagat ggtgaaattt tagctagatt
     8161 caatgataca aataaagtta ttgatgctat tgtcagcgca tccttgtccg cagtgctcga
     8221 tacatttatg ttaatcatgg ttgggatctt tttatatatt caaaatactt ctttgtttat
     8281 agtaacatta gctttaatcc ccttttatat tctaactgtt tgggttttta tgaagcccta
     8341 tgagagtatt aatgacaatg aaatggaaaa taatgctcaa ctcacttcaa aaattgttga
     8401 aacattaagt agtatagaaa caataaaagc ttacaatgct gaatatatta tgtcatttga
     8461 aactgaaaag cgatttgtga aatacttgca atcttctttt aaacacggtg taattgataa
     8521 tcttcaaagt tctattaagt tgtttctaga tttaataagt ggtgcattga tactatggat
     8581 cggcgcttgg caagtcataa agggaaatat gacaattggc cagttgatta catataacgc
     8641 actattggca tattttttga accctttaca aaatatcatc tcacttcaat ccaaacttca
     8701 gtcagcttcg gttgcttcaa agagattggg agaaatttta gatgaagaac ctgaaataca
     8761 aacatctgaa gcaagggtta ccgatccagc ctatatacaa ggccctattg aaataaacaa
     8821 tgttgatttt cgatacggaa ctcgaaggct catcttaaaa gatattacac tgcatattca
     8881 aaaaggagag aaagttgcct ttgttggaga aagcggttca ggaaaatcta ctttgactaa
     8941 gcttttaatg aaattttata cagctgaatc aggtgagatt ttaatcaatg gttatcatat
     9001 aaatgatatt cacaccaatg cgttaaggga aagcataagt tatatacctc aagaatctca
     9061 ttttatacaa ggatcaattc ttgaaaacct tttgcttggg aactcaggaa gttttacctt
     9121 cgaagagatt atagaagttt gcaaacaaac aaatgtacat gattttgtca atgatttacc
     9181 aatgagatac gatactctcg tagaggaaaa cgggtctaat ttatctggag gccagaagca
     9241 aagacttgca attgccaggg cattattaag aaaacctaac attcttataa tggatgaatc
     9301 aacaagcaac ctcgatacga cgaccgaaca gggaatatca aagatgattt acgctcagac
     9361 tgtcgatgta actacaatta taattgctca tcgtttaagt acaattatga attgcgacaa
     9421 aatatttgtc atggaaaatg gagaaatcat agagtatggg aaccacaatg atttattgaa
     9481 gaaaaaagga aagtactatg agttgtggga gaaccaaatg ccatcgagag agatggtgac
     9541 aatttagatg aaacgtaact ttttcaattt acatgatttg aaggatagca gagaattcta
     9601 cgaatcaaaa cccaaaccaa ttggtgtttt ctttacatat atactgatag ctttacttat
     9661 tgcatgtatt gtttttagtt tctatggaaa gaaagaagtg attctaaaaa cggcagctga
     9721 catccaatat acgaaaccta acagcaacgt aacaaacgaa gtagccggca aagtaaaaac
     9781 agttgatatt aaacaggttg ataaggtgaa aaagggggat actctattaa ctctagacaa
     9841 tactgaaatc caagcgcaga aaaaagctgt taaagcagat atcaaagatg taaaagaaca
     9901 agctgcgtta aacaaaactc taaaaaaaag tattgaaaat gacaaaaatt tattcagcga
     9961 ggacgatcat tggggttatc aagatcaata tctctcatac gaaaaacaaa gcaatttgtt
    10021 agagtcatca aaagaaaatg caaaaactca acagaaaaaa cttaagaagc agaaaaaaag
    10081 cataaaaaat agtctcgata agacaaaaaa caaagtgaaa cgaaagcttc aaagaatttc
    10141 tgatctgcaa gactccatta aaaacaataa atcctttgcc aaacaggatg ataagtacag
    10201 ttcttactat aatagttttc aaactaacaa acaaaatgta gagcagcagc ttgatgatct
    10261 acggaagatg aaagatgagc tcgataaaaa cagtttctca cagaagaaag agaatctaaa
    10321 cggacagctt gaaagtttaa aacaagatat gctagtaaaa ctaagcgaag aaaaagacga
    10381 attaaatcaa tcatttgatg agattaacag ttcaatgaaa agtgacgatt ctgacagtga
    10441 ttccgataac tcagaggaaa caaattataa gctttcaatt gaacagctta aaacaaattt
    10501 gctaaatcaa acatctcaaa agcaaacaga tcttcagacc actcttaaat caaaagaaga
    10561 tgatctaaag atgatagatt tacaattaga aaaatataaa ataaaagcaa caagtgacgg
    10621 ctatgttaat gtattaacaa atatatctcc aggtgattat ttacaagcag gcaccgccat
    10681 tttgactatt gttcctgata aagagaagct taaagctaac atttatattc cgagtcatga
    10741 gatcacaaat ataaatgaaa aagatgaagt aagattccat attgaaaata caaatcaaac
    10801 cgttaaaggt gtcattacaa aaataagtcc agacagtata agtgatcaaa gcgggcaaaa
    10861 attttatatt gctgaaagca caatagaaag taaagaaatt gaaaaaaata acggaacaaa
    10921 aatacactta aaaaatggca tgcagactga tgtatcaatt atcgttgatt ccaaaagata
    10981 tattgattat tttttagatg tattacactt acgttaattt ccatctagag aaaaagtgca
    11041 tatatgtctc aaaagcagat gaggatctgc tttgaggcat tttatttttt ataagaaagg
    11101 cagaggacgt atagaatcat gtctcaaaac aaactgttat ttttactctt tttattctct
    11161 tctatcgttc gccttttctt caatacagta ttgtccccca ctgtaagctg gaagtcttgg
    11221 acggtgaata ttgtttttat tcttttgttt cttctatttc tcaatctcac cttaaaagaa
    11281 agaaaatcaa aagaccaagt attataacga cccaaagccc ggatcaagtc tccgggcact
    11341 tcaaagcaaa acaaccttat acttcttcac atccaaaaac tgcaaaaact ccctcgccag
    11401 cacttccggc gcatgcgcct tcccttcatc gagccgatac aatatcagcc cgataatcta
    11461 cctttaaatc taatgcttcg atattctgca aaacgcgatc aaagtgcaaa gcctgaggct
    11521 cacatgggaa gatgtggcct tcatacgggt cgcctaacgt ccggaaaaac ggttcaaata
    11581 aaccaggaac caatacgccc accatctttg tatagtgaga atcaaggcga taggagtgaa
    11641 cggtatttgc agggacatgc aggaaatctc ccggattcag ctgaatttcc tggccatctg
    11701 cccacatcgt catctgacct tcaaggcaat aaaatgtttc tgtatgatgt tcatggtagt
    11761 gatcaacgat tcggtcacct ttagggcctt cagaggatac gacgataaac tggccatctg
    11821 tatttttttg tgcagccaca atgcggtgaa gctgatctcc agtcaacagg cgatctcctt
    11881 ctccagattc aagaacgtat ggaaccgctc catctggcag ctctgtaagt tccgctaatt
    11941 tggccgaaca tgcaggcttt ccttcatcta gaaatacaat gtccgctaca gcggctgctt
    12001 ctgcaaatcg ctcgtttgag acttcttcgc ttgcgtacgg cggatgttca gcgtgatcat
    12061 acggattccc aataacggaa tacaagtgcg ctacgtttcc tttcatcgtg taggacacca
    12121 gtcttgttct gtggctctgc atccggtagc tgtgcggtgt tcccgccgga atgttggcat
    12181 aatcacctga tattaataaa tagcgttcac cgtcaagtgt cagttccagt ttcccgtcca
    12241 aaacgagaat tccttcatgt gtgtccttgt ggacgtgaag cggaaaggca tctccttttc
    12301 ccccggaaag aagcacgatc tcaaacaaat cacctgtgct cctcccattc gccatcaccg
    12361 tggcaacctg tctgccgaac agatagcgct cgccttctcc gctccggagc aaataaggca
    12421 ttttttcttt aggcaatgaa tgtgtacata atgttttcat attatcgctt cctccaattt
    12481 agaccagtct atatattatc atttatttgt ctagaccgtt ctatataatt gtaggagaaa
    12541 ggataacaaa atgctaccct ttttttctca ccagcactgg tatttgttcg gcaatgagaa
    12601 gaagaggcgt tttgtcttta ttcgttaacg aaagcatgat gccgccctca atcatcgaat
    12661 taatcagcgt tccaagctga tttgcttctt catctgcaaa tccgttttcc attaattttc
    12721 tggcaaaaac cgcttcccag cttttaaaca ccttcatgca aaccgtccgc agcggttcac
    12781 tgattaacgc tgtctcactc gccagcaaac cgactggaat acctttaatg ctttctgtgt
    12841 tatcaaattg gctggctgtt tttttgataa aaagctgaat cgcttctgtt ggatcagagg
    12901 attcatccat gctttgctgt atcagatgtt caacgatctt acctgtatat gtaaccgctt
    12961 caattgctaa ttcttctttg ccattcggaa aaaagtgata aagcgatccc ttaggagcac
    13021 cgctttcttt tacaatctgg ttcaaacctg tcgcgtgata tccttgcagc tggaacagac
    13081 gtgacgccgt gtgaaggatt ttttcacgtg aatctcctct gctagtcatt aaaacattcc
    13141 ctcctaggta tggtagagcg acttatataa tataaaaaag aaccctgtga ttgtcaaaag
    13201 gggtaagacc cttccggatg gggtaatgta caaaaacagc gtctaggagg gatctctcaa
    13261 tgacaatcga tcattcagtc acaaatacag aacagcttga acgacaaaac cccgccataa
    13321 aaacaaagct caaactgaaa aagcttaagg atcaggtgat cgtcattacc ggcgcttcaa
    13381 gcggaatcgg acttgtcacg gcacgaatgg cagctgaaaa aggcgcaaag gtcgtggcag
    13441 cagcgcgaaa tgaagacgcg ctgaaggagc tcactgatga acttaaggaa aaagggcacg
    13501 acgccatatg ggtaaaggcg gatgtcggaa aagaagagga cgtcaaccgc atcgcagaaa
    13561 ccgcgatcag cacattcggc cgctttgaca catgggtcaa caatgcggcc gtctcgactt
    13621 tcggacatgc catggacgtc accgtcgaag acatgaagcg catgttcgac acaaatttct
    13681 ggggacctgt ttacggaaca agagcggctg tcaaacacta caccggcaga ggtgtgccgg
    13741 gcgcactcat taatgtagga agcctgttcg gagacagggg aacggtcatt caatccacat
    13801 atgcatctgc caaatttgcg cttcacggct ggacggaaag catccgaatg gagctcgaaa
    13861 aggaacaggc gcccgtctcg gtaacgctca tccacccggg cagaattgac acaccttata
    13921 acgagcatgc gcacagctac ctcgacaaac agccggctca ttaccgctcc atgatctatc
    13981 caccggaagc agtcgccgaa gcgatcctgt ttgccgccga acaccctaag cgcgacatgt
    14041 acatcggctc acaggccaaa gccatcgcca tgctgggcgc gcttttccct cgtctgaccg
    14101 acagactgat ggaaaaaatc atgtatcaca gccagcatgc cgaaaaaccg tccaaaccgc
    14161 gagaagaaag tgctctttat gatgcgggct gcggtatgca tgacagaggc acaaataaag
    14221 gatggatgag gtcaagaagc tactacacga atgcgacgaa gcgccccatt gtatctgcgg
    14281 ctgttgttgc aggactagtg gcttgggctg ccgccaaacg atgcagataa tctctgacca
    14341 tgatagaaaa acccatgctg ttccagcgaa ccatgggttt tttagctgtt aatcgataaa
    14401 agccttgttc atacgctgca gcagctcgcc gaacatctct ttttcctgtg ttgaccattc
    14461 tttcagcatc tgttcataac gttcaaggcg cttttgctga tcggctttta atagttgttt
    14521 gccgagtttt gtaatggtaa acaggct
//
