LOCUS gnlProkkaDKKBAMEE_59 25444 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|DKKBAMEE_59. ACCESSION gnlProkkaDKKBAMEE_59 VERSION gnlProkkaDKKBAMEE_59 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 06:09:52 Original ID :: gnl|Prokka|DKKBAMEE_59 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 25444 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..25444 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="True" /core_location="[1616:5444]" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" /tool="antismash" proto_core 1617..5444 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" cand_cluster 1..25444 /SMILES="NC(CC(C)C)C(=O)O" /candidate_cluster_number="1" /contig_edge="True" /detection_rules="cds(Condensation and (AMP-binding or A-OX))" /kind="single" /product="NRPS" /protoclusters="1" /tool="antismash" region 1..25444 /candidate_cluster_numbers="1" /contig_edge="True" /product="NRPS" /region_number="1" /rules="cds(Condensation and (AMP-binding or A-OX))" /tool="antismash" CDS 3..1580 /NRPS_PKS="Domain: PCP (1-49). E-value: 4.9e-18. Score: 57.0. Matches aSDomain: nrpspksdomains_ctg34_1_PCP.1" /NRPS_PKS="Domain: Epimerization (59-362). E-value: 6.6e-163. Score: 535.2. Matches aSDomain: nrpspksdomains_ctg34_1_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (366-515). E-value: 2.4e-54. Score: 175.2. Matches aSDomain: nrpspksdomains_ctg34_1_TIGR01720.1" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) Condensation" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127:condensation domain-containing protein (Score: 136.7; E-value: 2.1e-41)" /gene_kind="biosynthetic-additional" /locus_tag="ctg34_1" /sec_met_domain="PP-binding (E-value: 1.1e-12, bitscore: 42.2, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="Condensation (E-value: 8.8e-87, bitscore: 284.8, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="MDNFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHPTIEELTQY VERAEGKQADQGPVEGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAKKGFDPERVEKTL QALIEHHDALRMVFREENGDIVQAYQPIGESEVSFEIVDLYGSDEEMLRSQIKILANKL QSSLDLQNGPLLKAEQYRTEAGDHLLIAVHHLVVDGVSWRILLEDFASGYMQAEKEESL VFPQKTNSFKDWAEELAAFSQSAHLLQQAEYWSQIAAEKVSPLPKDCETEQRIVKDTSS VLCELTEEDTKHLLTDVHQPYGTEINDILLSALGLTMKEWTKGAKIGINLEGHGREDII PNVNISRTVGWFTAQYPVVLDISDADASAVIKTVKENLRRIPDKGVGYGILRYFTETAE TKGFTPEISFNYLGQFDSEVKTDFFEPSAFDMGRQVSGESEALYALSFSGMIRNGRFVL SCSYNEKEFERVTIEERMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGDIF DMLEENLK" aSDomain 6..149 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_1_PCP.1" /evalue="4.90E-18" /label="ctg34_1_PCP.1" /locus_tag="ctg34_1" /protein_end="49" /protein_start="1" /score="57.0" /tool="antismash" /translation="DNFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHPTIEELTQYV ERA" aSModule 6..1547 /domains="nrpspksdomains_ctg34_1_PCP.1" /domains="nrpspksdomains_ctg34_1_Epimerization.1" /domains="nrpspksdomains_ctg34_1_TIGR01720.1" /incomplete /locus_tags="ctg34_1" /tool="antismash" /type="unknown" CDS_motif 9..38 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_1_0001" /evalue="5.60E-03" /label="PCP_mC" /locus_tag="ctg34_1" /protein_end="12" /protein_start="2" /score="10.1" /tool="antismash" /translation="NFFSLGGDSI" aSDomain 180..1088 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_1_Epimerization.1" /evalue="6.60E-163" /label="ctg34_1_Epimerization.1" /locus_tag="ctg34_1" /protein_end="362" /protein_start="59" /score="535.2" /tool="antismash" /translation="EGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAKKGFDPERVEKTL QALIEHHDALRMVFREENGDIVQAYQPIGESEVSFEIVDLYGSDEEMLRSQIKILANKL QSSLDLQNGPLLKAEQYRTEAGDHLLIAVHHLVVDGVSWRILLEDFASGYMQAEKEESL VFPQKTNSFKDWAEELAAFSQSAHLLQQAEYWSQIAAEKVSPLPKDCETEQRIVKDTSS VLCELTEEDTKHLLTDVHQPYGTEINDILLSALGLTMKEWTKGAKIGINLEGHGREDII PNVNISRTVGWFTAQYPVVLDI" CDS_motif 195..224 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_1_0002" /evalue="3.20E-05" /label="NRPS-E1" /locus_tag="ctg34_1" /protein_end="74" /protein_start="64" /score="16.5" /tool="antismash" /translation="LTPIQRWFFE" CDS_motif 285..359 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_1_0003" /evalue="3.30E-07" /label="C2_LCL_024-062" /locus_tag="ctg34_1" /protein_end="119" /protein_start="94" /score="22.7" /tool="antismash" /translation="FDPERVEKTLQALIEHHDALRMVFR" CDS_motif 564..629 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_1_0004" /evalue="3.40E-12" /label="NRPS-E2" /locus_tag="ctg34_1" /protein_end="209" /protein_start="187" /score="38.4" /tool="antismash" /translation="LLIAVHHLVVDGVSWRILLEDF" CDS_motif 1032..1082 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_1_0005" /evalue="1.30E-08" /label="NRPS-E5" /locus_tag="ctg34_1" /protein_end="360" /protein_start="343" /score="26.8" /tool="antismash" /translation="NISRTVGWFTAQYPVVL" aSDomain 1101..1547 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_1_TIGR01720.1" /evalue="2.40E-54" /label="ctg34_1_TIGR01720.1" /locus_tag="ctg34_1" /protein_end="515" /protein_start="366" /score="175.2" /tool="antismash" /translation="ASAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFNY LGQFDSEVKTDFFEPSAFDMGRQVSGESEALYALSFSGMIRNGRFVLSCSYNEKEFERV TIEERMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGD" CDS_motif 1122..1181 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_1_0006" /evalue="7.80E-12" /label="NRPS-E6" /locus_tag="ctg34_1" /protein_end="393" /protein_start="373" /score="37.2" /tool="antismash" /translation="VKENLRRIPDKGVGYGILRY" CDS_motif 1215..1244 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_1_0007" /evalue="1.40E-03" /label="NRPS-E7" /locus_tag="ctg34_1" /protein_end="414" /protein_start="404" /score="11.0" /tool="antismash" /translation="PEISFNYLGQ" aSDomain 1617..1712 /aSDomain="NRPS-COM_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_2_NRPS-COM_Nterm.1" /evalue="1.40E-16" /label="ctg34_2_NRPS-COM_Nterm.1" /locus_tag="ctg34_2" /protein_end="32" /protein_start="0" /score="51.3" /tool="antismash" /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQ" CDS 1617..5444 /NRPS_PKS="Domain: NRPS-COM_Nterm (0-32). E-value: 1.4e-16. Score: 51.3. Matches aSDomain: nrpspksdomains_ctg34_2_NRPS-COM_Nterm.1" /NRPS_PKS="Domain: Condensation_DCL (9-308). E-value: 5.8e-119. Score: 388.5. Matches aSDomain: nrpspksdomains_ctg34_2_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (469-867). E-value: 4.8e-110. Score: 359.8. Matches aSDomain: nrpspksdomains_ctg34_2_AMP-binding.1" /NRPS_PKS="Domain: PCP (973-1042). E-value: 1.5e-25. Score: 81.1. Matches aSDomain: nrpspksdomains_ctg34_2_PCP.1" /NRPS_PKS="Domain: Thioesterase (1059-1259). E-value: 5.4e-37. Score: 120.2. Matches aSDomain: nrpspksdomains_ctg34_2_Thioesterase.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127:condensation domain-containing protein (Score: 333.6; E-value: 3.7e-101)" /gene_kind="biosynthetic" /locus_tag="ctg34_2" /sec_met_domain="Condensation (E-value: 2.1e-93, bitscore: 306.6, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 2e-121, bitscore: 399.3, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 8.5e-18, bitscore: 58.6, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKG SLNIKCLEESMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQT AKINEYKEQDKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLF KVYNALREQKPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEDFEGQTTFAEQRKKQ KDGYEPKELLFSLPEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVV SGRPAEIKGVEHMVGLFINVVPRRVKLSEGITFNGLLKQLQEQSLQSEPHQYVPLYDIQ SQADQPKLIDHIIVFENYPLQDAKNEESSENGFDMVDVHVFEKSNYDLNLMASPGDEML IKLAYNENVFDEAFILRLKSQLLTAIQQLIQNPDQPVSTINIVDDREREFLLTGLNPPA QARETKPLTDWFKEAVNVNPDALALTYFGQTLSYRELDEEANRLARRLQKHGAGKGSVV ALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKEQAA ELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANIQGL VKHVDYMAFSEKDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTDLIL QENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKALRVMGPGKLINCY GPTEGTVFATAHVVHDIPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCISGMG VSKGYVNRADLTKEKFIKNPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRI ELEEIEKQLQEYPGVKDAVVVADRHESGDASINAYLVNRTQLSAEDVKAHLKKQLPAYM VPQTFTFLDELPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNEMEETIAQIWSEVLGRKQ IGIHDDFFALGGHSLKAMTAASRIKKELGIDLPVKLLFEAPTIAGISAYVKNGGPDGLQ DVTIMNQDQERIIFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLIQK LQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVESDV EALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDMPE WLASWEEATTGAYRMKRGFGTHAEMLQGETLDRNAGILLEFLNTQTVTVS" aSDomain 1644..2540 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_2_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="5.80E-119" /label="ctg34_2_Condensation_DCL.1" /locus_tag="ctg34_2" /protein_end="308" /protein_start="9" /score="388.5" /tool="antismash" /translation="QDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKGSLNIKCLEE SMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQTAKINEYKEQ DKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLFKVYNALREQ KPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEDFEGQTTFAEQRKKQKDGYEPKEL LFSLPEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVVSGRPAEIKG VEHMVGLFINVVPRRVKL" aSModule 1644..5393 /complete /domains="nrpspksdomains_ctg34_2_Condensation_DCL.1" /domains="nrpspksdomains_ctg34_2_AMP-binding.1" /domains="nrpspksdomains_ctg34_2_PCP.1" /domains="nrpspksdomains_ctg34_2_Thioesterase.1" /final_module /locus_tags="ctg34_2" /monomer_pairings="Leu -> Leu" /tool="antismash" /type="nrps" CDS_motif 1653..1694 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0001" /evalue="3.00E-05" /label="C1_DCL_004-017" /locus_tag="ctg34_2" /protein_end="26" /protein_start="12" /score="15.8" /tool="antismash" /translation="YYLSPMQEGMLFHA" CDS_motif 1716..1832 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0002" /evalue="2.50E-12" /label="C2_DCL_024-062" /locus_tag="ctg34_2" /protein_end="72" /protein_start="33" /score="39.1" /tool="antismash" /translation="FYLEQITMKVKGSLNIKCLEESMNVIMDRYDVFRTVFIH" CDS_motif 2049..2114 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0003" /evalue="1.70E-11" /label="C3_DCL_135-156" /locus_tag="ctg34_2" /protein_end="166" /protein_start="144" /score="36.5" /tool="antismash" /translation="YHHIILDGWCFGIVVQDLFKVY" CDS_motif 2160..2198 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0004" /evalue="5.50E-04" /label="C4_DCL_171-183" /locus_tag="ctg34_2" /protein_end="194" /protein_start="181" /score="12.4" /tool="antismash" /translation="PYKDYIKWLEKQD" CDS_motif 2436..2531 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0005" /evalue="1.30E-18" /label="C5_DCL_263-294" /locus_tag="ctg34_2" /protein_end="305" /protein_start="273" /score="59.4" /tool="antismash" /translation="DLAFGTVVSGRPAEIKGVEHMVGLFINVVPRR" CDS_motif 2580..2693 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0006" /evalue="1.00E-17" /label="C67_DCL_14fromHMM" /locus_tag="ctg34_2" /protein_end="359" /protein_start="321" /score="56.6" /tool="antismash" /translation="QEQSLQSEPHQYVPLYDIQSQADQPKLIDHIIVFENYP" aSDomain 3024..4217 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_2_AMP-binding.1" /evalue="4.80E-110" /label="ctg34_2_AMP-binding.1" /locus_tag="ctg34_2" /protein_end="867" /protein_start="469" /score="359.8" /specificity="substrate consensus: Leu" /tool="antismash" /translation="FKEAVNVNPDALALTYFGQTLSYRELDEEANRLARRLQKHGAGKG SVVALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKE QAAELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANI QGLVKHVDYMAFSEKDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTD LILQENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKALRVMGPGKLI NCYGPTEGTVFATAHVVHDIPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCIS GMGVSKGYVNRADLTKEKFIKNPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIR" CDS_motif 3210..3251 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0007" /evalue="2.60E-05" /label="NRPS-A_a2" /locus_tag="ctg34_2" /protein_end="545" /protein_start="531" /score="17.4" /tool="antismash" /translation="LGVLKAGAAYLPVD" CDS_motif 3444..3503 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0008" /evalue="9.20E-08" /label="NRPS-A_a3" /locus_tag="ctg34_2" /protein_end="629" /protein_start="609" /score="24.4" /tool="antismash" /translation="AYIMYTSGTTGKPKGNITTH" CDS_motif 4011..4100 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0009" /evalue="5.50E-13" /label="NRPS-A_a6" /locus_tag="ctg34_2" /protein_end="828" /protein_start="798" /score="41.1" /tool="antismash" /translation="PFGAIGELCISGMGVSKGYVNRADLTKEKF" CDS_motif 4182..4247 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0010" /evalue="9.60E-12" /label="NRPS-A_a8" /locus_tag="ctg34_2" /protein_end="877" /protein_start="855" /score="36.8" /tool="antismash" /translation="YAGRIDDQVKIRGHRIELEEIE" aSDomain 4536..4742 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_2_PCP.1" /evalue="1.50E-25" /label="ctg34_2_PCP.1" /locus_tag="ctg34_2" /protein_end="1042" /protein_start="973" /score="81.1" /tool="antismash" /translation="EETIAQIWSEVLGRKQIGIHDDFFALGGHSLKAMTAASRIKKELG IDLPVKLLFEAPTIAGISAYVKNG" aSDomain 4794..5393 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_2_Thioesterase.1" /evalue="5.40E-37" /label="ctg34_2_Thioesterase.1" /locus_tag="ctg34_2" /protein_end="1259" /protein_start="1059" /score="120.2" /tool="antismash" /translation="IIFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADL IQKLQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVE SDVEALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFD MPEWLASWEEATTGAYRMKRGFGTHAEMLQGETLDRN" CDS_motif 4941..5015 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_2_0011" /evalue="6.30E-10" /label="NRPS-te1" /locus_tag="ctg34_2" /protein_end="1133" /protein_start="1108" /score="31.5" /tool="antismash" /translation="QPEGPLTLFGYSAGCSLAFEAAKKL" CDS 5473..6201 /NRPS_PKS="Domain: Thioesterase (14-231). E-value: 2.8e-55. Score: 180.1. Matches aSDomain: nrpspksdomains_ctg34_3_Thioesterase.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (smcogs) SMCOG1004:thioesterase (Score: 213.1; E-value: 5.1e-65)" /gene_kind="biosynthetic-additional" /locus_tag="ctg34_3" /sec_met_domain="Abhydrolase_6 (E-value: 5.4e-15, bitscore: 50.5, seeds: 455, tool: rule-based-clusters)" /sec_met_domain="PF00561 (E-value: 2.1e-06, bitscore: 21.4, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MSQLFKSFDASEKTQLICFPFAGGYSASFRPLHAFLQGECEMLAA EPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGV FPQAVIISAIQPPHIQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSD YRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQ TEEVAERIFAILNQHPIIQP" aSDomain 5515..6165 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_3_Thioesterase.1" /evalue="2.80E-55" /label="ctg34_3_Thioesterase.1" /locus_tag="ctg34_3" /protein_end="231" /protein_start="14" /score="180.1" /tool="antismash" /translation="QLICFPFAGGYSASFRPLHAFLQGECEMLAAEPPGHGTNQTSAIE DLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGVFPQAVIISAIQPPH IQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSDYRALEQFELYDLAQ IQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQTEEVAERIF" CDS_motif 5698..5769 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg34_3_0001" /evalue="1.90E-08" /label="NRPS-te1" /locus_tag="ctg34_3" /protein_end="99" /protein_start="75" /score="26.7" /tool="antismash" /translation="PDRPFVLFGHSMGGMITFRLAQKL" CDS 6302..7528 /gene_functions="transport (smcogs) SMCOG1137:Major facilitator superfamily MFS 1 (Score: 335.7; E-value: 5.1e-102)" /gene_kind="transport" /locus_tag="ctg34_4" /transl_table=11 /translation="MRTSPRMKWFVLLFTFVFAIGMNSFRNSFQFFMLPMADAFHADRS LISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISTSFLVLPYSPNVHVFSAI YGVLGGIGYSCAVGVTTQYFISRWFDIHKGLALAILTNANSAGLLLLSPIWAAAPYHAG WQSTYTILGIVMAAVLLPLLVFGMKHPPHAQAESVKKSYDWRGFWNVMKQSRLIHILYF GVFTCGFTMGIIDAHLVPILKDAHVSHVNGMMAAFGAFIIIGGLLAGWLSDLLGSRSVM LSILFFIRLLSLICLLIPILGIHHSDLWYFGFILLFGLSYTGVIPLTAASISESYQTGL IGSLLGINFFIHQVAGALSVYAGGLFFDMTHGYLLIVAVCIVFVGLSAVIELVPFLDKQ KAKETHHSI" CDS complement(7543..8100) /locus_tag="ctg34_5" /transl_table=11 /translation="MIQYASESINLPGEIAFKDVREIFFYQIAKISCFYFLLFCAIFTA VNFINGWPRIVYGSDALNLFMNSMLIIVMSVLFTLLLLLLLYVKFSRAYKKNERMKSKR TYTLNQEGIRICSKKYDLIFNWDEITAVFEYNNIFRVNTSSGQYIAIPKRFFHSKEEMN RFKEIILKNTGTKKLKFKKDQH" CDS complement(8154..9092) /gene_functions="transport (smcogs) SMCOG1166:transporter, EamA family (Score: 155.6; E-value: 3e-47)" /gene_kind="transport" /locus_tag="ctg34_6" /transl_table=11 /translation="MVKHQQAPAYIAATLYSFIIGLSFLFVKIALQTAEPFDILAHRFT IAFAAATVPILFGWVKLSIRVKDVIAILPLALLYPALFFSFQAFGLVYSSSSEAGIIQA AIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLILLSA LSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVGPYFLPFREPG FVLAIMYLGVLSSLVTSFLSNYTLSRIEAFKMSAFNHVSTIVTMIAGVVILNESLAWYH LAGAVCIMIGVVGSNINLEKKTKRPGMPAKK" CDS 9216..10550 /NRPS_PKS="Domain: Aminotran_1_2 (96-438). E-value: 1.4e-22. Score: 72.1. Matches aSDomain: nrpspksdomains_ctg34_7_Aminotran_1_2.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Aminotran_1_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1019:aminotransferase (Score: 260.3; E-value: 4.8e-79)" /gene_kind="biosynthetic-additional" /locus_tag="ctg34_7" /sec_met_domain="Aminotran_1_2 (E-value: 6.2e-22, bitscore: 72.1, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MEKYMSLVTRIEEMMQSTAYQEGDRLPSIRQLSARYQVSKSTVIR ALQELEKRHLIYSVPKSGYYIVKKTGKSKSGQLGPIDFATSAPDPDVFPYLDFQHCINK AIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFADERHIFITSGVQQALSLLCAMPF PNGKEKIAIEQPGYHLMVEQLETVGIPAIGVKRTEEGLDIAKVERLFQTESIKFFYTMP RFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYL KSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKE KIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASRVIHRLKK QGVLLEAIDRHYLSDYPKENLLKINISYVKTEDIERGVKLLMSHL" aSDomain 9504..10529 /aSDomain="Aminotran_1_2" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_7_Aminotran_1_2.1" /evalue="1.40E-22" /label="ctg34_7_Aminotran_1_2.1" /locus_tag="ctg34_7" /protein_end="438" /protein_start="96" /score="72.1" /tool="antismash" /translation="DFQHCINKAIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFAD ERHIFITSGVQQALSLLCAMPFPNGKEKIAIEQPGYHLMVEQLETVGIPAIGVKRTEEG LDIAKVERLFQTESIKFFYTMPRFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGD LEENKKADPLYAYDLSSHVIYLKSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDC SMISQAALEIYLKSGMYGRHKEKIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQAPC MHTHLVLPQDLPASRVIHRLKKQGVLLEAIDRHYLSDYPKENLLKINISYVKTEDIERG VK" CDS complement(10545..11219) /NRPS_PKS="Domain: ACPS (103-166). E-value: 6e-20. Score: 63.4. Matches aSDomain: nrpspksdomains_ctg34_8_ACPS.1" /gene_functions="biosynthetic-additional (smcogs) SMCOG1012:4'-phosphopantetheinyl transferase (Score: 189.2; E-value: 1.1e-57)" /gene_kind="biosynthetic-additional" /locus_tag="ctg34_8" /transl_table=11 /translation="MKIYGIYMDRPLSQEENERFMSFISPEKREKCRRFYHKEDAHRTL LGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVIGAFDSQPI GIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSL PLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEE LL" aSDomain complement(10722..10910) /aSDomain="ACPS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg34_8_ACPS.1" /evalue="6.00E-20" /label="ctg34_8_ACPS.1" /locus_tag="ctg34_8" /protein_end="166" /protein_start="103" /score="63.4" /tool="antismash" /translation="IGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWS MKESFIKQEGKGLSLPLD" CDS complement(11324..11971) /locus_tag="ctg34_9" /transl_table=11 /translation="MKQELVLRWTFYFAGLIILAFGVSLTIEGKALGISPWDAFHYSLF QHFGLTVGQWSIIIGALIVGFTSLFTRAWPKIGALLNMVLIGVFIDFFNFILPAPSTYT GSIIVFSLGVVLIGYGVGVYVSAGLGAGPRDSLMMLITEKTGWNVQWVRNGMEITILFA AWGMGGPIGFGTILTAILTGLILRFSLPQSIQLLNYAVARRTAAVKASPPVH" CDS complement(12292..13035) /gene_functions="transport (smcogs) SMCOG1000:ABC transporter ATP-binding protein (Score: 222.1; E-value: 1.3e-67)" /gene_kind="transport" /locus_tag="ctg34_10" /transl_table=11 /translation="MLTVKGLNKSFGENEILKKIDMKIEKGKVIAILGPSGSGKTTLLR CLNALEIPNRGELAFDDFSIDFSKKVKQADILKLRRKSGMVFQAYHLFPHRTALENVME GPIQVQKRNKEEVRKEAIQLLDKVGLKDKMDLYPFQLSGGQQQRVGIARALAIQPELML FDEPTSALDPELVGEVLKVIKDLANEGWTMVVVTHEIKFAQEVADEVIFIDGGVIVEQG PPEQIFSAPKEERTQRFLNRILNPL" CDS complement(13049..13753) /gene_functions="transport (smcogs) SMCOG1096:polar amino acid ABC transporter, inner membrane (Score: 244.4; E-value: 1.7e-74)" /gene_kind="transport" /locus_tag="ctg34_11" /transl_table=11 /translation="MFLNNLPALTLGTAIPWDLVQQSFWPILSGGIYYTIPLTILSFIF GMILALITALARMSKVRPLRWVFSVYVSAIRGTPLLVQLFIIFYLFPAFNVTLDPFPSA VIAFSLNVGAYASEIIRASILSVPKGQWEAGYTIGMTHQKTLFRVILPQAFRVSIPPLS NTFISLIKDTSLASQILVAELFRKAQEIGARNLDQILVIYIEAAFIYWIICFLLSLVQH VIERRLDRYVAK" CDS complement(13740..14546) /gene_functions="biosynthetic-additional (smcogs) SMCOG1091:glutamine-binding lipoprotein glnH (Score: 234.5; E-value: 1.7e-71)" /gene_kind="biosynthetic-additional" /locus_tag="ctg34_12" /transl_table=11 /translation="MKKALLALFMVVSIAALAACGAGNDNQSKDNAKDGDLWASIKKKG VLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLNSK RFDVVANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEADVKGKTSAQSLTSNY NKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAFETGD PQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK" CDS complement(14662..15534) /gene_functions="regulatory (smcogs) SMCOG1014:LysR family transcriptional regulator (Score: 246.3; E-value: 6.3e-75)" /gene_kind="regulatory" /locus_tag="ctg34_13" /transl_table=11 /translation="MDIRQLRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQLEDELGV VLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVGSTIYCAA LMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQFKQLDDI PCVLVLSDEAGYPCGDTIKMEDIPSFPLILLRPVNGKGVYNQVMNEFHRLNLEPRIVCE CHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWRTDSYLPK PAQQFLDLF" CDS 15624..16238 /gene_functions="biosynthetic-additional (rule-based-clusters) Flavoprotein" /gene_kind="biosynthetic-additional" /locus_tag="ctg34_14" /sec_met_domain="Flavoprotein (E-value: 1.8e-32, bitscore: 105.9, seeds: 143, tool: rule-based-clusters)" /transl_table=11 /translation="MKAEFKRKGGGKVKLVVGMTGATGAIFGVRLLQWLKAAGVETHLV VSPWANVTIKHETGYTLQEVEQLATYTYSHKDQAAAISSGSFDTDGMIVAPCSMKSLAS IRTGMADNLLTRAADVMLKERKKLVLLTRETPLNQIHLENMLALTKMGTIILPPMPAFY NQPSSLEEMVDHIVFRTLDQFGIRLPEAKRWNGIEKQKGGA" CDS 16241..17662 /locus_tag="ctg34_15" /transl_table=11 /translation="MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGAAARAASNLGDK SPALLFNNIYGYHNARIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMPVK REETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQNVGI YRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPLLYDQ SEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTGHYSGG RSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPNEIVAVN AMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFNLPQVMWA LSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHYSQPLDSPL TTKEWEQKLMDLMNK" CDS 17679..17906 /locus_tag="ctg34_16" /transl_table=11 /translation="MHTCPRCDSKKGEVMSKSPVEGAWEVYQCQTCFFTWRSCEPESIT NPEKYNPAFKIDPKETETAIEVPAVPERKA" CDS 17903..18367 /locus_tag="ctg34_17" /transl_table=11 /translation="MIGVNSMSDRLFELLDGRCLNEKQHEAFVLQTVSEDGWPHAAMIS AGEIIALSRTDIRIALWKNTMTSANILRTGKAQFTAWWKGAAYYVKLECAPLPPLKDAE YDRDRFSCRIVSVKEDVAKYADLTSGVRIQLHSPEEVLGRWEKTLEDLKR" CDS 18433..19278 /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (smcogs) SMCOG1036:alpha/beta hydrolase fold protein (Score: 65.1; E-value: 1.3e-19)" /gene_kind="biosynthetic-additional" /locus_tag="ctg34_18" /sec_met_domain="PF00561 (E-value: 1.4e-14, bitscore: 48.3, seeds: 48, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 3.3e-09, bitscore: 31.6, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MERAGICHSDGFDLAYRIEGEGAPILVIGSAVYYPRLFSSDIKQK YQWVFVDHRGFAKPKRELRAEDSRLDAVLADIERMRTFLQLEDVTILGHSGHAFMALEY ARTYPKQVRKVALFNTAPDNSEERQRKSESFFMETASLERKKRFEKDIANLPQDIDKDP ERRFVHMCIRAEAKSFYQERPHAAALWDGVFTNMPIMDELWGNTFAQIDLIQRLADVRM PVYIGLGRYDYLVAPVALWDAVDGLYSHVDKVIFERSGHQPMLEEPEAFDQSFSKWLDQ " CDS complement(19319..20797) /gene_functions="transport (smcogs) SMCOG1202:major facilitator transporter (Score: 52.1; E-value: 6.3e-16)" /gene_kind="transport" /locus_tag="ctg34_19" /transl_table=11 /translation="MASIDNESIIKSVPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAI LLYYLYTETVNGGLGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANTVFYGGIF IMFGHIALAYPGSAIAFYISMVLIIVGTGLLKPNVSSVVGDLYTKEDPRRDSGFSIFYM GINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVFALTRKKNLGLAGSNVPNPL SKKSAIGTGIGVIIVAIAVMISVQTGVLTINRFIDLVSILGILIPVIYFIIMFTSKKAD STEKSRLAAYIPLFIGAVMFWAIQEQGATILAVYADERIRLSLGGFELQSSWFQSLNPL FVVIFAPIFAWLWMKLGKRQPSTPVKFSIGIILAGLSFIIMVFPAMQGKEALVSPLWLV LSFLLVVLGELCLSPVGLSVTTKLAPAAFSAQTMSMWFLTNAAAQAINAQVAGLFDKIP ETMYFGTIGLISIVLGGILLLLSPVIKRAMKGVL" CDS 21077..22831 /locus_tag="ctg34_20" /transl_table=11 /translation="MAEFILNAADFGVPGDGKTDSTERINQCLSTAVSKGYHTVWFPKG TYLIDATLGGDLNQRFRNAGIIVPGNLEIMMDPECIMKVIPNSSWGYSAFYVGKQENIT ISGGQIIGERDEHTYASAGIRSTHEWGFGICIEGCSNVVIDDVKISDFTGDGIIVSPRG LKTNQDYRTSEQIIIRRCEVRRSRRNNISITGCDMVTVEACLIEDAGTGNGTAPKFGID IEGYGEGDVDYEEPINVSIRNNHFVGNVSSSVTNFNGYGILIEGNHSDNTISYGYGTQT VIKGNILRRPEDAAAAPRVGITGLGVSQGKETSDAVIAGNLITGFSTGIDVRGKSVLVT NNKISNFENTGILVYQSSDVKVDGNQIQNGLSETRRSIGLRAVLSDDTAFLNNCLIQVV DGVSVSGGNMIIKDNLLRKFSRGIWIAQGDAVIEGNTLNPGAFEAVPESYSVSVTNNAG AIIKNNTFKEFKNYPIYCSTSAKTSIIGNHLERSPLLVTIYISAGVHEIFDNTISVNRT AGNPIVIYLNGSAGSIIAGNTINNLSAGTATAIQTNTSTNSKIIGNRIFKGTINKHSSD AIDGNIIV" CDS complement(22846..23067) /locus_tag="ctg34_21" /transl_table=11 /translation="MKILGVTGVILICLLAISVLMDMLQGFSLTKAIYNNMSSFKMTTF AEWVVLLFFVLVLVREMYVIYKSKKKNP" CDS 23193..24827 /locus_tag="ctg34_22" /transl_table=11 /translation="MPLFSKRKNNTSSKDKRNTEEKNQEQKQEKERPVLISPSLAKNIA ETKKEVGSSSDVIIREIKIGEQDHVHLAVIYIAGLVDNNTIHESLIDPLVQDESIQNTH AIQQILEKTLPLGGVKAEKSWDKLFSELMLGNALIFADGYDEALICSTQGGEQRSIQEP STQVSFRGPRQGFTESLQTNISMIRRYIKNPNLWVEKMKKGSVTNTDIALMYIQGICDE KVLKEVKQRLEKIDIDSILESGYIEQLIEDETFTTFPTMYHTERPDVVAGNLLEGRFAI IVDGTPFVLIAPALFVQFFQSVEDYYSRFDIATSIRILRVLVFFISLVAPAVYVAATTF HQEMIPTQLLVVIAAQREIVPFPAVVEALTMEVAFEILREAGVRLPRVVGSAVSIVGAL VIGQAAVQAGIVSPAMVIIVALTAIASFATPAFAMAISARLIRFIFIIASAVMGFYGLI LGIIMMFVHLCSLRSFGVPYMSPLAPFSSQGVKDALFRVPWWADEKRPESVSKEDKVRQ GQDQRPEPAASRGMVNKDLEEGDQNGT" ORIGIN 1 tcaccgacaa tttcttctcg cttggcggag attccatcaa aggaattcaa atggcgagcc 61 gcttgaatca gcacggctgg aagctggaaa tgaaagatct cttccagcat ccgacgatcg 121 aagagctcac ccagtacgta gagcgtgccg aaggcaaaca ggcagaccaa ggcccggtgg 181 agggcgaagt catcctgacg ccgatccagc gctggttctt tgaaaagaac ttcacgaaca 241 agcaccactg gaaccaatcg gtgatgcttc acgccaagaa gggctttgat cctgaacggg 301 tggagaaaac attgcaggcg ctgatcgagc atcatgacgc gctccgtatg gtctttcgtg 361 aggaaaacgg ggacatcgtt caggcgtatc aaccgatcgg tgagagcgag gtcagcttcg 421 aaatcgtgga tctgtacggc tccgatgaag agatgctgag aagccagatt aaaattctcg 481 cgaacaagct gcagagcagt ctcgatctgc aaaacgggcc gcttctaaag gcggagcaat 541 atcgcacaga agctggggat cacctgctca ttgctgtaca ccatctggtg gtcgacggtg 601 tgtcatggcg gattttgctt gaagactttg cttcaggcta catgcaggct gagaaagaag 661 agagccttgt cttcccgcaa aaaacaaact ccttcaagga ctgggcggaa gaactggcgg 721 cattcagcca atcagcgcat cttttacagc aggctgaata ctggtcgcaa attgccgctg 781 aaaaggtttc tcctttaccg aaggattgtg aaacagagca gcggatcgtc aaggatacat 841 catctgtcct atgtgaatta acggaagaag acacgaagca tcttttaaca gatgttcatc 901 agccatatgg aactgaaatc aacgatattc ttctcagcgc gctcggtttg acaatgaaag 961 aatggacaaa gggggccaaa attggcatta accttgaggg acacggccgg gaggacatta 1021 tcccgaatgt gaatatctcc agaacggtcg gctggtttac ggcacaatac cctgttgtgc 1081 tcgacatatc tgacgcagat gcctcggctg tgatcaaaac agtcaaagaa aacctgcgcc 1141 gcattccgga caaaggtgtt ggctacggca ttcttcgtta tttcacagaa acagcggaaa 1201 caaagggctt cacaccggag atcagcttca actatttggg ccaattcgac agtgaagtca 1261 aaaccgattt ctttgaaccg tccgctttcg atatggggcg ccaagtaagc ggagaatcag 1321 aggcgctgta cgctttaagc ttcagcggca tgatcagaaa tggccggttt gtgctttcct 1381 gctcctacaa tgaaaaggag tttgaaagag tcacgattga agagcgaatg gaacggttta 1441 aagaaaacct cctgatgtta atccgccatt gcacggaaaa agaagacaag gaattcacac 1501 caagcgactt tagcgccgaa gaccttgaaa tggacgagat gggagatatc tttgacatgc 1561 ttgaggagaa tttaaaataa aacgcaaggg aattacagaa ggcgggagcg aaacatatga 1621 gtcaatttag caaggatcag gttcaagata tgtattacct atcgccgatg caggaaggga 1681 tgctttttca tgccatcctg aatcccggcc aaagctttta ccttgaacaa atcacgatga 1741 aagtaaaagg cagcttgaat atcaaatgtc ttgaagaaag catgaatgtg atcatggacc 1801 ggtacgatgt atttcgtacc gtgttcattc acgaaaaagt aaaaagacct gtccaagtcg 1861 tattgaaaaa acggcagttc catatagaag aaatcgatct gacacactta acgggcagcg 1921 agcaaacagc caaaatcaat gagtacaaag aacaggataa gatcaggggt tttgatttga 1981 cgcgggatat tccgatgcgg gcagccattt tcaagaaagc tgaagaaagc tttgaatggg 2041 tgtggagcta ccaccacatt attttggacg gatggtgctt cggcatcgtc gtacaggatc 2101 tatttaaggt atacaatgct ctgcgcgaac aaaagccgta cagcctgccg cccgtcaaac 2161 cgtataaaga ctacatcaag tggcttgaaa agcaggataa acaagcatcg ctccgctact 2221 ggcgcgagta cttggaggac tttgaaggac aaacgacgtt tgcggagcaa aggaagaaac 2281 agaaggacgg ctatgagccg aaagagctgc tcttttcact gccggaggcg gaaacaaagg 2341 cctttaccga gcttgcaaaa tcgcagcata ccactttgag tacggcgctg caggcagtct 2401 ggagcgtatt gatcagccgc tatcagcagt ctggcgattt ggccttcggt acagttgttt 2461 cagggcgtcc cgcggaaatc aaaggcgttg aacatatggt cgggctgttt atcaacgttg 2521 tcccgagacg tgtgaagctg tctgagggta tcacatttaa cggcttgctc aagcagctgc 2581 aggagcaatc gctgcagtct gagccgcatc aatatgtgcc gctttatgac atccaaagcc 2641 aggccgatca gccgaaactg attgaccaca tcattgtttt tgagaactat ccgcttcagg 2701 atgcgaaaaa tgaagaaagc agtgaaaacg gctttgatat ggtggatgtt catgtttttg 2761 agaagtcgaa ttatgatctc aacctgatgg cttcccctgg agatgagatg ctgattaagc 2821 ttgcctataa tgagaatgtg tttgatgagg cgtttatcct gcgcttgaaa tctcagcttc 2881 tcacagcaat tcagcagctc atccagaatc cggatcagcc tgtcagcacg atcaacatcg 2941 ttgacgacag ggagagagaa tttttgctaa ccggcttaaa cccgccggct caagctcgtg 3001 aaacaaagcc tctgacggat tggttcaagg aagcagtgaa cgtcaatccg gatgcactgg 3061 cgcttacgta tttcggccag accctgtctt atcgcgaatt agatgaggaa gcgaaccgcc 3121 ttgcacgccg gctgcaaaaa cacggtgcgg gcaaaggctc tgttgtagcg ctgtacacga 3181 agcgctcact tgaactggtg atcggcattc tcggtgtatt aaaggcggga gcagcctatc 3241 tgccggttga tccgaagctg ccagaggacc gaatctcgta tatgctggct gacagtgcgg 3301 cagcctgtct tctgacgcat caggagatga aagaacaagc ggctgagctg ccgtatacag 3361 gcacaacgct cttcattgat gatcaaacac ggtttgaaga acaggcaagc gatcctgcaa 3421 ccgcgattga tcctaatgat ccggcatata tcatgtacac gtccggcaca accggaaagc 3481 caaagggcaa tatcaccact catgccaata ttcaaggatt ggtcaagcat gtagactaca 3541 tggcattctc tgagaaagat acattcttgt ctgtttcgaa ttacgccttt gacgcattta 3601 cttttgattt ctatgcttct atgctgaatg cggcacggct cattatcgca gatgaacata 3661 cgctgcttga tacagaacgg ctcacagatc tgatcctgca agagaatgtc aatgtcatgt 3721 ttgcgacaac cgcactattt aatcttctca cagatgcggg agaggattgg atgaagggac 3781 tacgctgtat attattcggc ggagagcgcg cctcagtgcc tcatgtcaga aaagcgctgc 3841 gggtcatggg gccgggcaag ctgattaact gctacgggcc gactgaggga acagtgtttg 3901 cgactgctca cgtcgtgcat gatataccgg attccatctc ctcattgccg attggaaagc 3961 cgatcagcaa tgccagtgtt tatattctga atgagcaaag ccagctccag ccattcgggg 4021 cgatcggtga actgtgcatc agcggaatgg gcgtgtcaaa aggatatgta aatcgtgctg 4081 acctcacgaa ggaaaagttt atcaagaacc cgttcaagcc gggagaaacg ctttaccgca 4141 caggggattt agcacgctgg ctgccggatg gaacgattga atacgccggc cgtattgacg 4201 accaggtcaa aatacgcgga caccggattg agcttgaaga aatcgaaaag cagctgcagg 4261 aatacccagg tgtgaaagat gcggtcgttg tggcggaccg ccatgagtct ggcgatgcat 4321 caatcaatgc ctaccttgtg aaccgaacgc agctttcagc tgaggacgtg aaggcgcacc 4381 tgaaaaaaca gcttcctgct tatatggtgc cgcaaacctt taccttcttg gatgagcttc 4441 ctttaacgac gaacgggaaa gtcaataaac ggctgctccc aaaacctgat caggatcagc 4501 tggcggaaga atggattgga ccgcggaacg agatggaaga aacaatcgca caaatctggt 4561 ctgaggttct cggcagaaag caaattggca ttcatgacga tttctttgcg ctcggagggc 4621 attccttaaa ggccatgacc gccgcttccc gcatcaagaa agagcttggg attgatcttc 4681 ctgtaaagct tttatttgaa gcgccgacga tcgccggcat ttcagcgtat gtgaaaaacg 4741 ggggccctga tggcttgcag gatgtaacga taatgaatca ggatcaggag cggatcattt 4801 tcgcattccc gccggttctg ggctatggcc ttatgtacca aaatctgtcc agccgcttgc 4861 cgtcatacaa gctgtgcgcc tttgatttta ttgaggagga agaccggctt gaccgctatg 4921 cggatttgat ccagaagctg cagccggaag ggcctttaac attgtttgga tattcagcgg 4981 gatgcagcct ggcgtttgaa gctgcgaaaa agcttgagga acaaggccgt attgttcagc 5041 ggatcatcat ggtcgattcc tataaaaaac aaggtgtcag tgatctggac ggacgcacgg 5101 ttgaaagtga tgtcgaagcg ttgatgaatg tcaatcggga caatgaagcg ctcaacagcg 5161 aagccgtcaa acaaggcctc aagcaaaaaa cacatgcctt ttactcatac tacgtcaacc 5221 tgatcagcac aggccaggtg aaagcagata ttgatctgtt gacttccggc gctgattttg 5281 acatgccgga atggcttgca tcatgggaag aagctacaac aggtgcttac cgtatgaaaa 5341 gaggcttcgg aacacacgca gaaatgctgc agggcgaaac gctagatagg aatgccggga 5401 ttttgctcga atttcttaat acacaaaccg taacggtttc ataaatgaag tgatgaaagg 5461 aggagacagc caatgagcca actcttcaaa tcatttgatg cgtcggaaaa aacgcagctc 5521 atctgttttc cgtttgccgg cggctactcg gcgtcgtttc gccctctcca tgcttttttg 5581 cagggggagt gcgagatgct cgctgccgag ccgccgggac acggcacgaa tcaaacgtca 5641 gctattgagg atctcgaaga gctgacggat ttgtacaagc aagaactgaa ccttcgccct 5701 gatcggccgt ttgtgctgtt cggacacagt atgggcggaa tgatcacctt caggctggcg 5761 caaaagcttg agcgtgaagg cgtctttccg caggcggtta tcatttctgc aatccagccg 5821 cctcatattc agcggaagaa agtgtcccac ctgcctgatg atcagtttct cgatcatatt 5881 atccaattag gcggaatgcc cgcagagctt gttgaaaata aggaggtcat gtcctttttc 5941 ctgccttctt tccgatcaga ttaccgggct cttgaacaat ttgagcttta cgatctggcc 6001 cagattcagt cgcctgttca tgtctttaac gggcttgatg ataaaaaatg catacgagat 6061 gcggaaggct ggaagaagtg ggcaaaagac atcacattcc atcaatttga cggcgggcac 6121 atgttcctgc tgtcacaaac ggaagaagtc gcagaacgga tttttgcgat cttgaatcag 6181 catccgatca ttcaaccgtg atcaaaagcg gacagcttcg gctgttccgc tttttttgtg 6241 tagaatgcca acttttgcat ggtataatag tcgaaatact caaacaaagg caggtcgaaa 6301 catgcgcacg tctcccagga tgaaatggtt tgtattgctg tttacgtttg ttttcgccat 6361 cggaatgaac tcattcagaa attcctttca attttttatg ctgccaatgg cggatgcctt 6421 ccatgccgac aggtcgctga tttcggtttc tgtcagcatt tttatgatca caaccggcat 6481 cgtccagttt tttgtcggtt tttttatcga ccgtttcagt gtcagaaaaa ttatggcgct 6541 tggagctgtc tgcatcagca caagcttttt ggtgcttcct tattcaccga atgttcatgt 6601 gttttccgcc atttacggtg tgcttggcgg aatcggctat tcctgcgcgg tcggcgtgac 6661 gacccagtat ttcatcagcc gttggtttga catacacaaa ggtctggcgc ttgctatttt 6721 gaccaatgcc aactctgcgg gcctgctgct tctctcgccc atttgggctg cggctccgta 6781 tcatgcaggc tggcagagca cctatacgat tttgggaatc gtcatggcgg ctgttctgct 6841 gccgctcctc gtctttggga tgaagcaccc gccgcatgcg caagcggagt ctgtgaaaaa 6901 atcttatgat tggcgggggt tttggaacgt gatgaagcaa tcccgcctca ttcatatcct 6961 gtacttcggc gtgtttactt gcggatttac aatgggaatt attgatgctc acctcgtccc 7021 gatacttaag gatgcgcatg tctctcatgt caacggaatg atggccgcgt tcggggcgtt 7081 tatcatcatt ggcggattat tggcaggctg gctgtccgat ctcctcggga gcagaagcgt 7141 catgctatcc atcttatttt tcattcggct gctcagcctc atttgcctgc tcattcccat 7201 tctcggaatt catcacagcg acctttggta cttcgggttt atcctgttat tcgggctcag 7261 ttacacaggc gtgatcccgc tgaccgcggc gtcaatttcg gaaagctatc aaacaggatt 7321 gatcggatcg ctgttaggca tcaatttctt tatccatcag gttgccggag ctctcagcgt 7381 gtatgcgggc ggtttgtttt ttgacatgac tcatggttat ttgctgattg tcgctgtgtg 7441 catcgtgttt gtgggtttat cggctgtaat agagctggtg ccgtttttag ataaacagaa 7501 ggcaaaagaa acccaccatt caatataaaa ggatcagcac tgtcaatgct gatccttttt 7561 aaatttgagt ttttttgttc cggtattttt aaggataatc tccttgaatc tgttcatttc 7621 ctctttggaa tgaaaaaaac gttttgggat cgcaatatat tggccacttg atgtattgac 7681 cctgaagata ttattatatt cgaaaacagc tgtgatttca tcccaattga aaatgaggtc 7741 atatttttta gaacatatac gaattccttc ttggttcaga gtatatgttc ttttagattt 7801 catccgttcg ttcttcttgt atgctctgga aaacttcaca tatagaagaa ggaggagcag 7861 cagtgtaaac agaactgaca tcacgataat caacatactg ttcataaaca agttaagcgc 7921 gtcactgcca taaacgatac ggggccatcc gttaatgaag ttaactgcag taaatatggc 7981 gcaaaacaac agaaagtaaa agcatgatat ttttgcgatt tgataaaaaa agatttctct 8041 tacatcctta aaagcgattt ctcctggaag attgatactt tcactagcat attgaatcat 8101 acggtaaacc tacacctcta accatgtttt tcctttcagt ctagcataat ttctcatttt 8161 tttgcaggca taccagggcg ctttgttttt ttctccagat tgatattgct ccccaccacg 8221 ccaatcataa tacaaacagc cccggcaaga tgataccagg ccaggctttc gttgagaatc 8281 acaactcctg caatcatcgt cacaatggta gatacatgat taaaagcgct cattttaaac 8341 gcctcaattc gcgacagcgt atagttagac agaaatgaag tgacaagtga agacagcacg 8401 cccaaataca taatggcgag aacgaagccg ggctcccgga acggcagaaa ataagggccg 8461 actgttcccg ccgctccgtg acgcacaagg gcgatggcgt tgaagacgac aaagccgatg 8521 gctgacatga tgtaggtgag ctctgtcagc ttgaaccgct gcgtcatttt tctggcagca 8581 gtattgtaca tcgctgaaga caaagcggac aataggatca gcaaagaccc ttttaagctg 8641 gctgattcca cgtcaacgcc tttcatcaca aaaataaaca tgacgccggc aacggataaa 8701 accgtgaacc ccttttgcgt ccacgttggg cgttccttta aaacataagc ggcaaagacc 8761 atcgtgaaaa tcggaatggc tgcctgaata attcccgctt cagaggagga cgagtacaca 8821 aggccgaatg cctgaaagct gaaaaataac gcgggataca gcagggcgag cggcaaaatg 8881 gcaatgacgt cctttacgcg gattgatagc tttacccagc cgaataaaat cggtacagtg 8941 gccgcagcaa acgcaatggt gaaccgatgc gccaaaatat caaacggctc tgctgtttgc 9001 agtgcgattt ttacgaatag aaaggataaa ccgataatga acgaatataa agtagccgct 9061 atataagcgg gggcttgctg atgtttaacc ataatgggaa gggctccttt acctgaattg 9121 cagcgccggt cgctcccttt attgtatggc cgcggtcaga acggtacaat gagaaaaaca 9181 atgaactgta ccggtacaaa acagggggag aaggcatgga gaaatatatg agtctagtaa 9241 cgaggataga ggagatgatg caaagcaccg cctatcaaga aggagacagg cttccatcta 9301 tccgtcagct gtccgcccgc taccaagtca gcaaaagcac agtgatccgc gcgctgcagg 9361 agctggaaaa gcgccacctt atctattctg ttccgaaaag cggctattat attgtgaaaa 9421 agacagggaa atcaaaaagc gggcagcttg gccccatcga ctttgccaca tctgcgccgg 9481 atccagatgt gtttccgtat cttgattttc agcactgtat caacaaagcg attgatacat 9541 acaaaaacga tttgtttatt tatgggacgc caaaggggct tccatcactc atccgcgtac 9601 tccgaaagct cttggccact caacaggtat ttgcggatga acggcatatt ttcattacat 9661 caggtgtcca gcaggcgtta tccttgcttt gtgccatgcc gttcccaaat gggaaagaga 9721 agatcgccat tgaacagccg ggctaccatt tgatggtcga acagcttgag acggtcggga 9781 ttcccgccat cggggtgaaa cgaacagaag aagggcttga tatagccaag gttgagcggt 9841 tatttcaaac agaatcgatt aaattttttt atacgatgcc gcgcttccat aacccgcttg 9901 ggtgctcatt gtcagagcgt gataaacagg agcttgtgag actggcagaa gcgtatgatg 9961 tctatctcgt tgaggatgat tacctcggtg atctggagga aaataaaaag gcagatccgc 10021 tgtacgcata tgatctgtcc tcacatgtca tctatttgaa aagcttctcg aaaatgatgt 10081 tccccggcct ccgcgtgggg gcggctgttt tgcccgaagc gctgactgac acgttctatg 10141 cgtacaaaaa actgaacgac atcgactgtt cgatgatttc tcaagcggca ttggagattt 10201 acctgaaaag cggtatgtat ggaaggcata aggagaaaat cagagattct tataaagagc 10261 ggtcgctgag gctacatcaa gccattcgaa ctcacaggca gctgggaagc ggacgcttta 10321 cgttctccag cgggcaggca ccctgtatgc acacccatct ggtgcttcct caggatctgc 10381 ccgcctcaag agtgattcat agactgaaaa aacaaggggt tctccttgag gcgatagacc 10441 gtcattattt atcagattat ccgaaagaaa atctattaaa aatcaatatt tcctatgtga 10501 aaacggaaga tattgagcgc ggtgtcaagc tgttgatgag ccatttataa aagctcttcg 10561 tacgagacca ttgtgatatc ctcggggaaa tcagggtgtg cggcgcatac agccattttg 10621 tagccgggat cgacctcata cgttttgata tagcatgggg aatggctgtc cggaagctca 10681 atggatactt gtccgtcctg gtgcaggcgc actgaaaagg aatcaagcgg aagcgataag 10741 cctttgcctt cctgtttgat aaaactttct ttcattgacc atagatgata aaaatagtct 10801 gtctgctcgt ccttgtcttt tgctaaaagg tcgctgtact ctgtttttga aaagaagcgc 10861 ttggcgatct caaggctgat cggtttcgtt ttttcgatat ctatgccgat cggctgtgaa 10921 tcaaacgcac caatgaccca gcggccggag tgagaaatgt tgaaatgagc gtcgggaaga 10981 tcagggatgc acggcttccc gtattcctgc gtgctaaagc ggatatcgga tttgtccaac 11041 tgatactgcc tgcttatgac tgagcgaacg agcacatctc ccagcagggt gcggtgagca 11101 tcttctttat gataaaatct ccggcatttc tcccgttttt caggtgatat gaaagacatg 11161 aaccgttcat tttcttcctg tgaaagcggg cggtccatat aaattccgta aatcttcatt 11221 ctagatcctc cgtctgcaaa agattgtcaa aaccatccta tcatacttcc acaagactca 11281 tatagaggag aaaataaaaa aacaaagcca aggcggcttt gttttagtgt acaggcggag 11341 atgctttcac agcggcggtc cgccttgcca cagcataatt cagcaactgg attgactggg 11401 gcaatgaaaa gcgcaaaata agtcctgtga ggatggcggt caaaatggtg ccaaaaccga 11461 tcggcccgcc catgccccat gctgcaaaca aaatggttat ttccatgccg ttccgcaccc 11521 attgcacatt ccagccggtt ttttctgtaa tcagcatcat cagtgaatca cgcggccccg 11581 cgccaaggcc tgctgataca taaacaccga cgccgtaacc gatcagcacc acgcctagag 11641 agaagacgat gatcgagcct gtgtaggtcg agggggcagg cagaatgaaa ttgaaaaaat 11701 ctataaatac accaatgagc accatattca ggagggcccc aattttcggc caagctctcg 11761 taaacaatga cgtgaatccg acgatgagcg ctccaataat gatggaccac tggccgacgg 11821 taagcccgaa gtgctgaaac aggctgtaat gaaatgcatc ccacggacta atgccgagtg 11881 cttttccttc tatcgtcagg gatacaccaa aagccaaaat gatcaaaccg gcaaaataaa 11941 atgtccagcg cagaacaagt tcttgcttca cgtgaggtcc cttctttcgt aaaaatcagt 12001 cgattgtcat tgtagcacat ctgacagaag ggcggaatag gcgaaagggg ctcaacaaaa 12061 aaacagggtc gccgcaggcg ccctgtttca gcgtgttggc aaacccttgc attcgttgtc 12121 aggcctgtgc ttcggtgctc acgaatttaa cattcgctgt gctccaatgc tcgcccttcc 12181 tagacttcaa aggttttcaa tcacgctgaa aatcacaaaa tcctaaaacg aaaatcgttt 12241 taggattttg tcaataatct gaaacagggc gatggcgccc tgtttttctt attacagcgg 12301 gttcaaaatc cggttcaaga accgctgtgt ccgttcttct tttggtgcag agaaaatttg 12361 ctccggcggt ccttgctcca cgataacgcc gccgtcgatg aagatgactt catccgcaac 12421 ttcctgcgcg aacttgattt cgtgggtcac gacgaccatg gtccagcctt cattggccaa 12481 gtccttgata accttcagca cctctccgac aagctcggga tcaagcgctg aggtcggttc 12541 gtcaaacagc atgagctcag gctgaatcgc cagtgcgcgg gcgatgccga cgcgctgctg 12601 ctggccgccg gaaagctgga acggatataa atccattttg tccttcaatc cgactttatc 12661 aagaagctga atcgcttctt ttctgacttc ctctttgttc cgtttttgca cctgaatagg 12721 gccctccatc acgttttcga gggctgtgcg gtgcgggaac aggtgatacg cctgaaacac 12781 cattccggat tttcggcgaa gctttaggat atccgcctgt ttcacctttt tggagaaatc 12841 gatggagaaa tcatcaaatg caagctctcc gcgattcggg atctccagag cgttcaggca 12901 gcgaagcagc gtcgttttcc ctgaacctga aggcccaagt atggcgatga cttttccttt 12961 ttcaatcttc atatctatct tttttaaaat ttcattttca ccgaatgatt tgtttaatcc 13021 tttaacggta agcatactcg gaacctcctt atttggccac gtagcggtca agacgccgtt 13081 cgatgacatg ctggacgagt gagagcagga agcagataat ccaataaata aaggctgctt 13141 caatatagat cactaaaatt tgatcaagat tccgcgcgcc gatttcctgg gcttttctga 13201 acagctcagc gaccagaatt tgagaggcga gggatgtatc tttaatcagg ctgataaagg 13261 tattggataa tggcgggatc gacacacgaa acgcctgcgg caaaatgacg cggaacagcg 13321 ttttttgatg tgtcatgcca attgtgtagc cggcttccca ttgccctttc ggcacggata 13381 aaatagatgc ccgaatgatt tcagatgcat aggcgccgac gtttaaagaa aaggcgataa 13441 ctgcgcttgg aaatggatct aatgtgacgt taaaggccgg gaacagatag aaaatgatga 13501 acaattgaac gagaagagga gtgccgcgta ttgcggatac gtatacgctg aacacccatc 13561 tcaaaggtct cactttcgac attctggcaa gcgccgtaat cagcgccagg atcattccga 13621 atataaagga aagaatcgta aggggaatcg tatagtagat tccccctgaa agtatcggcc 13681 agaatgactg ctgcaccaga tcccacggga tcgccgtgcc aagcgtcaat gccggcagat 13741 tatttagaaa catcttcgcc gaaccatttt ttagatattt tagaaagagt cccgtcctct 13801 ttcatttctt ttaatgcttt gttgacttga tcaacaacct cgccgcttcc tttacggaac 13861 gtgaaatatg ttgactgagg atcacctgtt tcaaacgcga ttttcacgtt tttattgcca 13921 gatgttttta agtagttcaa tacggcaagc ttatcgttgt atgtcatatc gacgcggcct 13981 tgctggatca tttgaagggc ctgcgccata ccttcaacgc cttctacttt agcgccggca 14041 tttgtagcta atttgttgta gttgcttgtc agtgattgag ctgacgtttt tccttttaca 14101 tctgcttcag acttaatatc gttgttgtct tttttcgtta cgacaacggc tcttgatgtt 14161 gtgtatttat ctgagaaatc atatttgtct tcacgatctg tttttccgac ttggttggca 14221 acaacgtcaa accgtttgga attcaggccg gcaaacatac tgtcccactg tgtttcctta 14281 aagtcgactt taagcccgag gcgttttgcg acttctgtga taacttcgac atcatagcca 14341 gtcaatttat cagtgtcttt gtcgtggtaa gtgaacggct catatgttcc ttccgttccg 14401 actgtgagca cacctttttt cttaattgaa gcccaaagat cgccatcttt ggcattatct 14461 tttgactgat tgtcatttcc tgctccgcaa gctgcaagag ctgcaatact tacgaccatg 14521 aataaagcca ataatgcttt tttcatctta ttccccactt ttctggttga ttttattgaa 14581 ataaaaaaat agcttacaaa tctaaaggat aacttttttt tagtatgagt caagtaattg 14641 gttttcataa ggcaaaatct tttaaaataa atccaaaaat tgctgtgccg gtttaggcaa 14701 ataactgtcc gttctccaca tgacagccgg tgtcataatg aagggattat tttcgatatg 14761 gacggtgtga acgtgatttc tcatatgaac gggaatcatt gtgacgggca aaatagacgc 14821 gccgaatccg gatgacacga ggctgagcaa agttgcagag tcgtggcatt cacaaacaat 14881 gcgcggctcc aggttcaaac gatgaaattc attcatgacc tgattataga cgccttttcc 14941 gttgacaggc cgcagcagga tcagcggaaa tgaaggaatg tcctccatct taatggtgtc 15001 tccgcacgga tatccggctt catctgaaag cacgagcaca catggaatgt catcaagctg 15061 tttgaattgt actgtatcac ttttgatcag tgttgtcgtg accgccgcat cgatttgccg 15121 gctttccagc agctccaaca gtgtcgcggg ttcattttcc caaatattaa aggtgagatg 15181 ggggtatctc tctttgatct gtgttacttt ttcaagcatc agagccgcgc aataaatcgt 15241 tgatcccacg gcaagtgtgc cggctacttc ctccttcagc tcctgtacct caatgactgc 15301 atcttcaaac ctatgcagaa tctcttttgc tctttttaga aaaacagctc cttcatatgt 15361 aagagtcatt tgttttttct tgttacggtc aaacagaaca acaccaagtt cgtcctccag 15421 ctgtttgagc tgcctgctta aaggcggctg cgccatgtga agctttttgg ctgcggacgt 15481 aattttctgt tcttgggcaa tggtaatgaa gtatcgaagc tggcgaatat ccaaaagaaa 15541 gcgcctcctt atcatacctt ttaggtatta aatatagatt taatagatat ttttcatatg 15601 gatatatcag gagtatgatt gaaatgaaag cagaattcaa gcgtaaagga gggggcaaag 15661 tgaaactcgt tgtcggaatg acaggggcaa caggggccat tttcggggtc aggctgctac 15721 agtggctgaa ggccgccgga gtggaaaccc atctcgttgt gtctccttgg gcaaacgtca 15781 cgatcaaaca cgaaacaggc tataccttac aagaagtaga acaactggcc acatacactt 15841 actcacataa ggatcaggcg gcagccattt caagcgggtc gtttgatacc gatggaatga 15901 ttgttgcgcc gtgcagcatg aaatctctcg cgagcattcg caccggcatg gcggataatc 15961 tgctgacacg tgcggcggat gtcatgctca aggagagaaa aaaactcgtc ctcttaacga 16021 gagagacgcc tttgaaccaa attcatctcg aaaatatgct agcgcttacg aaaatgggca 16081 caatcattct tcctccgatg ccggcatttt ataatcagcc gagcagctta gaggaaatgg 16141 ttgaccatat tgtattcaga acgttggacc aattcggcat tcggcttcct gaagcgaagc 16201 gctggaatgg gattgaaaaa caaaaaggag gagcttgatc atggcctatc aagatttcag 16261 agaatttctc gcagcccttg aaaaagaagg acagctgctt acagtgaatg aagaggtaaa 16321 gccggaaccg gatttagggg ccgccgcacg ggcagccagc aatcttggcg ataaaagccc 16381 cgcgctctta tttaacaaca tttatggcta tcataacgcg cgaattgcga tgaatgtcat 16441 cggctcttgg ccaaaccatg caatgatgct gggcatgccg aaagacacac cggttaaaga 16501 acagtttttt gaatttgcga agcgttatga ccagtttccg atgccggtca aacgtgagga 16561 aacagcgcca tttcatgaaa atgaaatcac agaagatatc aatttgttcg atatactgcc 16621 tcttttcaga attaaccaag gtgatggagg ctactattta gacaaagcat gtgtcatttc 16681 ccgtgatctt gaagaccctg acaacttcgg caaacaaaat gtcggcattt acagaatgca 16741 ggtcaaagga aaagaccgtc tcggcattca gcctgttccg cagcacgata ttgcaatcca 16801 tctgcgccaa gctgaagaac gcggcatcaa ccttccggtc actattgcgc tcggctgtga 16861 gccggtcatt acaacggcgg catcgactcc gcttctctat gatcaatcag aatacgaaat 16921 ggcaggtgcg attcaaggcg aaccatatcg catcgtcaaa tcaaagctgt ctgatctgga 16981 tgttccgtgg ggcgctgaag tggtgcttga aggtgagatt attgccggag agcgcgaata 17041 tgaagggccg ttcggtgaat tcacaggcca ttattccggc ggacgcagca tgccgattat 17101 caaaattaaa cgcgtctatc acagaaacaa tccgatcttt gaacatttat acttaggcat 17161 gccttggaca gaatgcgatt acatgatcgg cattaacaca tgcgtgccgc tttatcagca 17221 gttaaaagaa gcgtacccga acgaaattgt ggcagtgaac gccatgtaca cacacggttt 17281 aatcgcgatt gtttccacaa aaacccgcta tggcggattt gcgaaagcgg tcggcatgcg 17341 cgcactcaca acgccgcacg gactcggcta ctgcaaaatg gtcattgtcg ttgatgagga 17401 tgtcgatcca ttcaaccttc cgcaggtcat gtgggcgctt tcgaccaaaa tgcatccgaa 17461 acacgatgcg gtcatcattc cggacttatc tgtcctgccg cttgatccgg gatccaatcc 17521 atcaggaatc actcacaaaa tgattcttga cgccactaca ccggttgcgc cggaaacaag 17581 aggccattat tcacagccgc ttgattctcc gctaacaacg aaagaatggg aacaaaaact 17641 aatggactta atgaataaat aaggaaagga tgttcgaaat gcatacatgt cctcgatgcg 17701 actcaaaaaa gggagaagtc atgagcaaat cgcctgtaga aggcgcatgg gaagtttatc 17761 agtgccaaac atgctttttt acatggagat cctgtgaacc ggaaagcatt acaaatcccg 17821 aaaaatacaa tccagcgttt aaaattgatc caaaggaaac agaaacagca attgaagttc 17881 cggcggtgcc ggaacgaaag gcttgatcgg cgtgaacagt atgtcagacc gtctctttga 17941 gctgcttgac gggagatgcc tgaatgagaa gcagcatgag gccttcgttc tgcaaacagt 18001 atcagaggat ggctggccgc atgccgctat gatcagtgcg ggtgaaatta tcgcgctgag 18061 ccgaactgat atccgaatcg ctctgtggaa aaacacaatg acttcggcca acatccttcg 18121 cacaggaaaa gcacagttca cggcgtggtg gaagggagcg gcctattatg taaagcttga 18181 atgcgcgcct ttaccgcctt tgaaagatgc cgaatatgat agagaccgtt tttcctgccg 18241 catcgtttca gtgaaggagg acgttgcgaa atacgctgat ttgacttcag gtgtccgtat 18301 acagcttcac agccctgaag aggtgctggg cagatgggaa aagaccctgg aagatttaaa 18361 gcggtaatat cgatagcctg acgccatgcg tcaggctttt tttatataat gaaaacaaag 18421 ggggcgtgag aaatggaacg tgcggggatc tgtcactcgg acggctttga tttagcttat 18481 cgaattgagg gcgagggcgc acccatcctt gtgatcggga gtgcggttta ctatccgcgc 18541 cttttttcct cagatatcaa acagaaatat caatgggtct ttgtcgacca taggggattt 18601 gctaagccta agcgggagct tcgtgcggag gattcgaggc ttgatgccgt cttggctgat 18661 atcgaaagga tgagaacatt tcttcagctt gaggatgtta ctatcctggg acattccggg 18721 cacgctttta tggctttaga gtatgccagg acatatccca aacaagttcg gaaggtggcg 18781 ctcttcaata ctgcgcctga taacagtgaa gaaagacagc gaaaaagcga atcatttttc 18841 atggaaacag ccagccttga gagaaagaaa cgatttgaaa aagacatcgc gaatttgccg 18901 caggacatcg acaaagatcc tgaaaggcgc tttgtgcaca tgtgtattcg cgctgaagcg 18961 aaaagctttt atcaagagcg gccgcatgct gctgccttat gggacggtgt attcacgaat 19021 atgccgatca tggatgaatt atggggcaat acatttgccc agattgatct tattcagcgg 19081 ttagctgatg ttcgtatgcc ggtgtatatc ggattaggga gatatgatta tttggttgcg 19141 cccgttgcgc tatgggatgc agttgacggt ttatattccc atgtggataa ggttattttt 19201 gaaaggagcg gccatcagcc gatgctggaa gaaccggaag cctttgatca aagcttcagc 19261 aaatggctgg atcaataaaa aaacagcccg cagatcaaaa tccgcgggct gtttctgatt 19321 ataagacccc tttcatcgca cgtttgataa ccggcgagag cagcaggaga atgccgccaa 19381 gaacgataga aatcaaaccg atggtgccga agtacattgt ttcaggaatt ttatcaaaca 19441 atccggctac ttgggcattg atcgcttggg ctgctgcgtt cgtcagaaac cacatactca 19501 ttgtctgtgc agagaaggca gctggggcca gtttcgttgt cacggataaa ccgactggag 19561 acaggcacag ctctccaagc acgacaagca ggaagctgag aacgagccaa agcgggctta 19621 cgagtgcttc ttttccttgc atagcaggga ataccataat gataaatgac aatccggcca 19681 aaataattcc gattgagaat ttaactggtg tagaaggctg gcgtttgcca agcttcatcc 19741 agagccatgc gaatattggc gcaaaaatga caacaaacaa tggatttaat gattggaacc 19801 aagatgactg aagttcgaat ccgcccaatg aaagtcttat gcgttcatca gcgtataccg 19861 caagaatggt cgctccctgt tcctgaatgg cccagaacat gacagcaccg ataaacaaag 19921 gaatgtaagc ggcaagacgg gatttttctg tgctgtccgc ttttttgctt gtaaacatga 19981 tgatgaaata aatgacagga atcaaaatac cgagaatact tacaaggtcg ataaaacgat 20041 tgatcgtcag cacgcctgtt tgtacagaga tcatcactgc gatcgccacg atgataacac 20101 cgattccggt gccaatcgca gattttttag acagcggatt cggcacattg gaacctgcaa 20161 gcccgaggtt tttctttctt gtcaaagcaa aaacgataag tccgagaagc attccgaccg 20221 cggcagctcc gaagccgaga tgatagttgt acttctgtcc gagtgttccg acaattaacg 20281 gtgcaagtaa accaccgagg ttaatcccca tgtagaaaat actgaaacct gagtcgcggc 20341 gcgggtcttc tttcgtgtaa agatccccaa ccacgcttga aacgtttggt tttaataagc 20401 ctgttccgac aataataagc accatgctga tatagaatgc gatcgcgctg cccggatagg 20461 cgagtgcaat gtggccgaac ataatgaata tgccgccgta aaaaacggtg tttgcggtac 20521 cgaatacccg gtcagcgagc catccgccaa taatggtgga catgtatacg agtgatccgt 20581 aaatcgacat aatggcaacc gcagtgccct tgtcaaagcc gagccctccg tttaccgtct 20641 ctgtatacaa atagtaaagt aagattgctc tcattccata gtaagagaaa cgctcccaaa 20701 attcggtgaa aaatagtgta aatagtcctc gcgggtgacc aaagaaccct ttttgcggga 20761 cgcttttaat gatactttcg ttatcaatcg aagccatgtc agccaaaccc tttctaaaaa 20821 aagtgtatta taaaaatcat attcttatat aatacttgtg tcaatataat ttatactcat 20881 ttcaaatagt tccataatgg aaaaattata aatacctaaa aatagtgatt ttctcctaat 20941 ttttatactc tttatcgtga gattttctta cacaactatt cctttatatt tttttaataa 21001 aattttagag aaatgtacaa gcagatcggg cctttgtgag taacatgata gtaatcatag 21061 agaaggaggc tcgcaattgg ctgaattcat attaaatgca gcggatttcg gtgttcctgg 21121 agatggtaaa acggattcga cagaacggat taatcagtgc ctcagtacag ctgtttcgaa 21181 aggctatcat actgtctggt ttccaaaggg aacatattta atagacgcaa cgcttggcgg 21241 agatcttaat cagaggtttc gaaacgcggg gatcattgtt cccggcaacc ttgagattat 21301 gatggacccc gaatgtatca tgaaagtgat accgaatagt tcgtggggtt attccgcatt 21361 ttatgtaggc aagcaagaga atataaccat ttccggggga caaattatcg gcgaacggga 21421 tgagcatacg tatgcctcgg cagggataag gtcaacccat gaatggggct ttggcatatg 21481 tattgaagga tgctcgaatg ttgtcattga tgatgtgaaa atttccgatt ttaccggcga 21541 tgggatcata gtcagcccaa ggggattaaa gaccaatcaa gattatcgaa cgtcagagca 21601 aattatcatc cgccgctgtg aggttcggcg gtcgaggaga aataacattt ccattaccgg 21661 atgtgacatg gtcacggtgg aggcatgctt gattgaagat gccggaacgg ggaatggaac 21721 agcgccgaaa ttcggaattg acattgaagg atatggcgaa ggtgatgttg attatgagga 21781 accgattaat gtatcaattc gcaataacca ctttgttgga aacgtttcaa gttctgtgac 21841 caattttaac gggtatggca ttttaataga aggaaatcac tcagacaata caatcagcta 21901 cggatatggg acgcaaacag tgatcaaggg aaatatactg aggcgccctg aagacgcggc 21961 ggctgcgcca agagtcggga taaccggact cggtgtatca caaggaaaag agaccagtga 22021 tgcagtgatc gctggcaacc tcattaccgg attttcaaca ggaattgatg tcaggggaaa 22081 gagcgttctt gtgacgaaca acaaaatcag caactttgaa aatacaggga tattggttta 22141 tcagtcctcc gacgtaaagg tagacggaaa ccaaattcaa aacggactgt ctgaaacaag 22201 gcgcagcatc ggtcttcgtg cagtgctttc agatgacacc gcttttctga ataactgtct 22261 cattcaagtc gttgacggtg tgagcgtttc gggcggaaac atgatcatta aagataatct 22321 cctgagaaaa ttcagccgag gcatttggat tgctcaaggg gatgcggtga ttgaagggaa 22381 tacactgaat cctggcgcgt ttgaagcagt gccggaatca tattctgttt ccgttacaaa 22441 caatgccggc gctatcatca aaaacaatac atttaaagag tttaaaaatt accccattta 22501 ctgctccaca agtgcaaaaa cctcaattat cggcaaccac ttagagagat ctccgctttt 22561 ggtcaccatc tatatcagcg ccggtgtgca tgagattttt gataatacca tttcagtcaa 22621 cagaacagcc gggaatccga ttgtgattta tctcaatggc tctgcaggct caatcatcgc 22681 aggaaacacc atcaataacc tctccgcggg cactgctaca gctattcaaa caaacacgtc 22741 aaccaattcc aaaatcatcg gcaaccgcat ttttaaaggg actatcaaca aacacagcag 22801 tgatgcaata gacggcaata ttatcgtctg aaaaaagcgc cccctctagg ggttcttttt 22861 tttcgattta tagatcacgt acatttctct cacaagtact aacacaaaaa ataaaagcac 22921 gacccattcc gcaaatgttg tcatcttaaa gctggacata ttgttataaa tggcttttgt 22981 taaactgaac ccttgaagca tgtccatcaa tacagaaata gctaataaac aaattaatat 23041 aactcctgtc acgcccaata tcttcatgct tcatcatcct ccgcttttag tgtctatcgt 23101 tggcggagaa gttataccgc atctaaacct aatgcataat ctcaatttta aaaggaagaa 23161 tatgagaaaa cgacaaggaa aggtatttgt gtatgccttt attttctaag cgaaagaaca 23221 atacaagttc gaaagacaag cgcaatacag aagaaaagaa tcaggaacag aagcaagaaa 23281 aagaaaggcc ggttctcatt tctccaagtt tggcaaagaa tatagcggaa acgaaaaagg 23341 aagtcggaag cagctctgac gtcatcattc gcgagattaa aatcggggag caggatcatg 23401 tccacctggc tgttatctat attgctgggc tggtcgataa taacacgatc catgagtcat 23461 taattgaccc attggtacag gatgagtcta tccagaatac tcatgcgatc cagcaaattc 23521 ttgaaaaaac gctcccgctg ggcggggtga aagcggaaaa gagctgggac aagctttttt 23581 ccgagttaat gctcggcaat gcgctcattt ttgctgatgg ctatgatgaa gctttgattt 23641 gcagcactca agggggagag cagcgctcca tccaagagcc gagcacccag gtgtcattcc 23701 gcggcccgcg ccaagggttt acagagtctc tgcaaaccaa tatttccatg atccggcgat 23761 acattaaaaa tccgaattta tgggttgaaa aaatgaaaaa aggttctgtt acgaatacgg 23821 atatcgctct catgtacatt caaggaatat gtgatgaaaa ggtgctgaag gaagtgaagc 23881 agcgcctgga aaaaatagat attgacagta ttttggaatc tggatatatt gagcagctga 23941 ttgaagatga aacctttacg acgtttccga ctatgtatca tacagaacgc cctgatgttg 24001 tagcgggtaa tctgttagaa ggaagattcg cgattattgt cgacggaaca ccgtttgtgc 24061 ttattgcccc ggccttattt gtccagtttt ttcagtctgt tgaggattat tattcgcgtt 24121 ttgacattgc gacaagcata agaattcttc gtgttttagt ctttttcatt tcgcttgtgg 24181 ctccggctgt atacgtggca gccacgacgt ttcatcaaga aatgataccg actcagctgt 24241 tagtggtcat tgcggcccag cgggaaattg tcccgtttcc ggctgttgtg gaggcgctga 24301 cgatggaggt tgcttttgag attctgaggg aagcgggagt caggctgccc cgggttgtcg 24361 gctcggcagt gtcaatcgta ggcgcgctcg taatcggcca ggctgccgta caagctggca 24421 tcgtctctcc ggcaatggtg attatcgtgg cactcaccgc gattgcgagc tttgcaacac 24481 cggcgtttgc aatggcgatt tcagctcggc ttattcggtt tatctttatt attgcctcag 24541 ctgttatggg tttttacggg ctgattttag ggatcattat gatgtttgtc cacttatgca 24601 gtcttcgttc attcggcgtt ccatatatgt cgccgcttgc acccttttct tcacaaggcg 24661 taaaggacgc gcttttcagg gttccgtggt gggccgatga aaaaaggccg gaatcggtca 24721 gtaaggaaga taaggtgcgg caggggcaag atcaacgccc agagccggcc gcttcacgag 24781 gaatggtgaa caaagatttg gaagaagggg atcagaatgg tacgtaaatg tctattagcc 24841 gttctcatgc ttttgagcgt cattgtgctg cccggctgct gggataagcg ggagctgacg 24901 gatcttgcga ttatctcggc gattggcatc gatcggacaa acgacagcaa ctacgtgctg 24961 catcttcaaa ttatcaatcc aggaaatgtt gccggcggcc ttcagggagg cggtgctgga 25021 gacaggccgc ctgtatctgt ctattcgatt gaaggtaaca atataacgga agcgctcaga 25081 aaagcctcca tgaaggtatc acggcggctt tattttgccc ataccaatct agtcgtgatc 25141 aatgaaaagc tggcaaaaga agaaggtttg gattttgtat tagataatct tgaccgggac 25201 acagaattca ggacaacagc aacattcgtc gttgcccata aaacaaaagc agaaaatatc 25261 gtaaaaatcc tgacgccgat tgataaaatt ccgtcaaata aagtcaataa aacactcgat 25321 ttcacggagg cgcaatacgg gcgggtggtc aaaaccaata ttcaggacgt tttgaaaaca 25381 cttgccgcca acactatggc accggttatc ccgggatata tgatgattgg tgacgataaa 25441 aaag //