LOCUS       gnlProkkaIPMMDEBB_11   16146 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IPMMDEBB_11.
ACCESSION   gnlProkkaIPMMDEBB_11
VERSION     gnlProkkaIPMMDEBB_11
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 06:14:02
            Original ID  :: gnl|Prokka|IPMMDEBB_11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 167040
            Orig. end    :: 183186
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16146
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:11146]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..11146
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16146
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16146
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(714..1790)
                     /locus_tag="ctg11_165"
                     /transl_table=11
                     /translation="MNINKIFLLNFNDTNDFNIKQVAIENDKVVSFSKSIKNISEYGMK
                     NYFDLAESLENPKKYSISLGENDEKTYHIDLLEKIRSSLDEADFLENIELAVDNGKLLY
                     NIAIYVEDDEKYTGIYIYEIKESHLLRDDFYVMKIPFTKQKINLKKKGAGTTNEKLAVV
                     ENVAGSVGLPTEGCIVSFFKRKKDDEQYKIYKVKVYDAWKFDDVFGKVETRKKYVRFTL
                     EKFANEENPIKIANDAVQVVFKNEDEETSNVVDTVEAVIMSDMKLVKTFSNFHNNSRRK
                     IKNIEVSRLREVLNLLKDYVLNNAEANFELKNIPTLDEKGNLIVNADSTPIFAALLENK
                     IIQRLLNNDIEIPYYKKD"
     CDS             complement(1795..2292)
                     /locus_tag="ctg11_166"
                     /transl_table=11
                     /translation="MSSTSSKITILIMLLSILVDLYSLVRVIQLLNNQKKLTKALGTNS
                     VRISNEYNGGLRDFLLSFIVPAITTFSADENPLTMIIFILLFQFIVYVFYKNSSDFFPN
                     ISLMFMGYSVFKVDTYDLGGIEYVFGKTKNIDDIILKKVDVIMIGDKNYPNNVAIILEK
                     KV"
     CDS             complement(2769..3173)
                     /locus_tag="ctg11_167"
                     /transl_table=11
                     /translation="MKKVLVDTCVIIDILLDREKFVDDSYSAVSKLIRKGDTICTTAKA
                     MTDIFYIVHHSLHDNDKTKEVLLKLSRVYQILDTKEKDTIMAITSDVADYEDAVMVETA
                     IANKVDFILTRNIKDYKKAKIKVISPTELN"
     CDS             complement(3173..3394)
                     /locus_tag="ctg11_168"
                     /transl_table=11
                     /translation="MTQVTATELKNNLGKYLKKSEFEDIYITKNGVIVSVLSNPNQSKL
                     QMLDDLKGIAPDMNMTDEELRSERISNI"
     CDS             complement(3837..4985)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 56.4; E-value:
                     3.8e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_169"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSARFRNFSTMIIIPFTILLLAVVIFSFFGKKEI
                     TIQGAGTLEALGNNPVIQSTVNSPIEKNYLKEGKYVKKGDTLLVYNNVNIQDKGKLYNS
                     QKEILDRQLAALNLLKQGVQDNHDSFGEDDEFGYRNDLKSYLQQRNTYLTENTMIQDKS
                     KNDKAKQSSINNELKKQGGSATSIADFDSSKYDIDINNQKMSDLQSSKLSSIDQEIIKI
                     KQNISELNANIDENNNTNREYKVKAVRDGILHINDEYSESHYISAGANLAQILPILKNQ
                     KTLKIKAYISTADISSIKVGQKVRFKVTRNVPKPIILTGKIHKISISPVEIGKENYYQI
                     EAKTDIQNTNRDLLKYGMQGQMVVITGKTTFFEYYKDKLFNR"
     CDS             complement(5001..7160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 309.2; E-value:
                     9.6e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_170"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.9e-44, bitscore:
                     143.6, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1079.5,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKYKKYYIPQVDESDCGVASLAMILKHYGSSLSLAYLRNIAKT
                     TMEGTTALGLVKTAQTLGMETQAVKADMSLFGMKDITYPFIVHVVKEETLLHYYVVLKA
                     TPNYILIADPAPDVGITKMSYERFEKEWTGITLFIVPGIEYKPTKETRQSLISLFSKLF
                     KQKQLIVNIVLAALLITIISILGSYFLQGIIDTYIPNGMHSTLAIIAFGLLVIYVFNSI
                     FTYARDFLLAILGQRLLIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVVSIFLDVSIVVIMGIILAIQNLKLLGITLISLPIYTIIILTFTKAFERLNNKQMES
                     NAILSSSIIEDIQGIETIKALNSEQMRYRKIDSQFVDYLRKSLAYIKTDSLQQALKLFI
                     QQTLNVIVLWLGANLVISNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDRKAVHDVTQLQGNIIFQDVDYRYGYGENILDKVNLTLKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFAPVSGSIKLNNHDINNIDKHTLRSYINYIPQNPYIFAGTIE
                     DNLRLGNRSNVTDEDILMACKIAMIDTDIAKMPLQLKTKLDENANILSGGQKQRITIAR
                     ALLSPAQVLIFDESTSELDAITEKKLIDNLMKLKSKTIIFIAHRLSIAKRTNNILVLDG
                     GKIVEKGRHDELLAKKGYYYNLINS"
     CDS             complement(7371..7568)
                     /locus_tag="ctg11_171"
                     /transl_table=11
                     /translation="MKINKKFYKNYTFYIGLVMLSIAVGSIFLDKGYFLFTIIDILFTC
                     LGIKYVYQSLVLTKRYERNR"
     CDS             complement(7813..8052)
                     /locus_tag="ctg11_172"
                     /transl_table=11
                     /translation="MVEIGIIILLVVGFMVISRLKVNFTKNSRYAGFLLLILLDLNGLM
                     RTPMLTVRGLILLGTLMIFVIMLIKEIRQNRKYS"
     CDS             complement(8089..8883)
                     /locus_tag="ctg11_173"
                     /transl_table=11
                     /translation="MEEYGIIICDDEKDQVRRIHDLVKYAIWSLEDSADSKDKEFKITL
                     EANSYIEVADYLEDNKVDSGVYFLDIELSRDKADRDGIDLAEFIRQRDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDSDEVIQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDILYIITTPKSHRLEIVTVNGMGEFTGDIKKLEAENDFLEKISQSCLANPS
                     NIVEINLSTRVISFKDGYKETFPRRSKAKMKSLIERYNLKTV"
     CDS             complement(8897..10189)
                     /locus_tag="ctg11_174"
                     /transl_table=11
                     /translation="MTDIVDIYNRYNIIIYAVGLFISVACDYLFFYLITPINRSKKQNI
                     LFTIITFPIVFLYHGGGDLGAFCAELFEVSAFYIVYKRRKRDYQVLGRILILLLYSYLS
                     FEIEFLLSQIISQYISTLPIDTIVINILEYYILMKTDIIKNLDDEYGKTFFYLIIYLLV
                     SFAGIYYLTGYLFKVDKVLYLILLVVIIVQLIFSLYIYNNSKKIRQDKLSLQQIKDLKI
                     YTQQLESSQRSLRKFKHDYQNMLVSLKLSAKKNHDKELIDKLAEYSSKILEDKVLWQFN
                     DVDNIKDELLKSLFISKLNRIFQDNIQYSFECRDVIDSLSNEYNAFDIIRILGITYDNA
                     IEESLELGDEARIDTMVYRENGELEIEIKNRCRNTDLTIQDMKKSGFTTKKNHDGLGLA
                     NIEELSQPYNDIFINYQIKDGWFTFLMVMSI"
     CDS             complement(10191..10310)
                     /locus_tag="ctg11_175"
                     /transl_table=11
                     /translation="MKFEVLTEKKLQVIVGGKQEGGTKTYDKVCRFKFLGICK"
     CDS             complement(10472..10591)
                     /locus_tag="ctg11_176"
                     /transl_table=11
                     /translation="MIFWVTVIVAYSIFISIYTSEKEDGHYRLFDKRKNTIKK"
     CDS             complement(10728..10934)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_177"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.7e-11,
                     bitscore: 36.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLDKRFTIMTEDNLASVNGGKNGYGGSGNRWVHCGAGIVGGAL
                     IGAIGGPWSAVAGGISGGFASCH"
     CDS             complement(10952..11146)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_178"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.4e-16,
                     bitscore: 53.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKEFTVLTECELAKVDGGKRGPNCVGNFLGGLFAGAAAGVPLGP
                     AGIVGGANLGMVGGALTCL"
     CDS             complement(11152..11409)
                     /locus_tag="ctg11_179"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEDMS
                     YLDYIQTPKMIIVAIFCLIGGSTLLYLLDTTMKVNKHMKG"
     CDS             complement(11539..11712)
                     /locus_tag="ctg11_180"
                     /transl_table=11
                     /translation="MNNNFVQIDKKELAHIIGGRNSYDYIDSGKFGYDIGCTIANTKFF
                     KRLRHSNQNICS"
     CDS             11945..12208
                     /locus_tag="ctg11_181"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLFLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFEATDDKHPLNRIDFGLQLLFIFISIIKFFLISGR"
     CDS             complement(12247..12576)
                     /locus_tag="ctg11_182"
                     /transl_table=11
                     /translation="MKAIYKGKEVQIWQISKTAEQPEWIKAAFKANYLKWSGDKLLFIM
                     NGVKAPVKISAWTNFKTLFNGASGWWATYASGYIGDYLDFTNRKIISERKFKKKYKIVD
                     TYVNK"
     CDS             12798..13772
                     /locus_tag="ctg11_183"
                     /transl_table=11
                     /translation="MRYIKFTLLIYSFLLTWGITTNSISADEVTPTTTSETIVTPQSQS
                     TPVDSNDEDAVIEEKFYSHDVTIDEYNENVANFNKVNTDTVKTMITENSNNLDQVLYIG
                     RPTCYFCRQASPHLRDFNQLINNQLYYYDIDTEPNAHDFAFKEIGIPGTPTTIRLKNGK
                     VISAWIGGEKTGQEFYDFLFSADANKLANSYTIKKTVSTDTSNPVITNNQNIEPIVKPI
                     STNISQLKEEKNTTELVNTTSQPFKPVKKIQNPATTTNKKNKNSVLPQLGAVPPYHQPL
                     FKLPIPRLIPKRLERIIALVSFLVLYIGITIWTGLSLKNWDKK"
     CDS             complement(13949..14290)
                     /locus_tag="ctg11_184"
                     /transl_table=11
                     /translation="MKVIYRGRKVDVWQVSRDNVQPDWVKYAFEHNGLRWLHGSGNKVR
                     IYWPAVTRAKKGIIRTILNGISASLVSINGGSASMYDIGFEGDVIDFTNSKVVTAEKFA
                     KKYRVVSEE"
     CDS             complement(14311..14580)
                     /locus_tag="ctg11_185"
                     /transl_table=11
                     /translation="MMDYLVIKAIIWIFFILSAILEVNYKKKYGELDKRARKQATLGIF
                     LIVTTIFDEGYENKILYTIVLIALLVYIVLVMYRLVMAIKDRKK"
     CDS             complement(14739..15917)
                     /NRPS_PKS="Domain: Aminotran_1_2 (32-385). E-value:
                     2.1e-72. Score: 236.1. Matches aSDomain:
                     nrpspksdomains_ctg11_186_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 278.1; E-value:
                     1.9e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_186"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.6e-72, bitscore:
                     236.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFEKSEILKNLPKQFFANLVIKVNKKIAEGVDVINLGQGNPDKQ
                     TPEYIVKSTQRWVASPQSHKYSLFRGQPEFKQAVADFYQEKYQTTFDPEKEVAVLGGSK
                     TGLVELPLALMNPGDVFLLPDPGYPDYWSGATLGQVTFEKVPLLKENNFLPDLKSIPEE
                     LAKKAKFFYINYPNNPTGATATREFYEELVAWAKKYEVGIISDFAYGAIGFDGEQPLSF
                     MEIPGAKDVGIEFYTFSKTFNMAGWRVAFAVGNADIIDALNLIQDHLFVSIFPALQYAG
                     IDALKAPERDAEINKIVDRYETRRNAFIQAAEKIGWKAFVPKGTFYAWMEVPKGYSSEE
                     FADLLLNEAGVAVAPGNGFGEYGEGYVRIGLLIEPERLEEAVDRIAKLNLFK"
     aSDomain        complement(14763..15821)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg11_186_Aminotran_1_2.1"
                     /evalue="2.10E-72"
                     /label="ctg11_186_Aminotran_1_2.1"
                     /locus_tag="ctg11_186"
                     /protein_end="385"
                     /protein_start="32"
                     /score="236.1"
                     /tool="antismash"
                     /translation="DVINLGQGNPDKQTPEYIVKSTQRWVASPQSHKYSLFRGQPEFKQ
                     AVADFYQEKYQTTFDPEKEVAVLGGSKTGLVELPLALMNPGDVFLLPDPGYPDYWSGAT
                     LGQVTFEKVPLLKENNFLPDLKSIPEELAKKAKFFYINYPNNPTGATATREFYEELVAW
                     AKKYEVGIISDFAYGAIGFDGEQPLSFMEIPGAKDVGIEFYTFSKTFNMAGWRVAFAVG
                     NADIIDALNLIQDHLFVSIFPALQYAGIDALKAPERDAEINKIVDRYETRRNAFIQAAE
                     KIGWKAFVPKGTFYAWMEVPKGYSSEEFADLLLNEAGVAVAPGNGFGEYGEGYVRIGLL
                     IEPERLEEAVDRI"
ORIGIN
        1 ccgaatactc gtctattttt aacggattcc agtataggaa ctactcttat attagtttta
       61 tctatttttg tatgtgtttt ttctgtaatt tataataaac actctcgttc tctttggtat
      121 atattttctt ttatattagg attaagtcct atactatttt taattttcgt tggtattttt
      181 ttagcattag gaatgccttt tgcaccatga ttaactttca agtagaaacc ggaaaaattt
      241 aaaaaatcgg ttctattcta tagcttgata aatagtaata agtctgctgc atattaagta
      301 agttaacaag ccatagatag ttattagaga gtaagagaat aataatagta atttaacagc
      361 taatagagaa taaattgata atgatgagtt agatagctgt cagatagtaa agcggttact
      421 tatagaattg agtaggagat aattgattaa ttcaattatc gacctctcac accaccgtac
      481 gtacggatcc gtatacggcg gttcgacaat ttaatcactt tgtattgact ggagtatctt
      541 gaacatgttt attagtccta gttgctccag tcttctatta gttagggtat acgcccacag
      601 cggactctca ccgcctagct atcgcccatg ccgggcgcac cacaaaagta gctggaatca
      661 tctgattctg gctacttttg ttttatatca ggtatcaaag gccaaacata cattcaatct
      721 tttttataat acggtatttc aatgtcgtta tttaataatc tttgaattat tttattttct
      781 aataaagctg caaatattgg tgtagagtct gcatttacta ttaaatttcc tttttcatct
      841 aaagtaggaa tattttttaa ttcaaaattt gcttcagcat tattcagtac ataatctttt
      901 agtaaattta atacttctct taatctagaa acttctatat ttttaatctt acgtctagaa
      961 ttattatgga aattcgaaaa agtttttact aatttcatat ctgacataat tactgcttct
     1021 accgtatcta ctacattaga ggtttcttca tcttcattct taaatactac ttgaacagca
     1081 tcattcgcta tttttatagg attttcctca ttcgcgaatt tttccagtgt gaatcttaca
     1141 tacttctttc gagtttctac ttttccgaaa acatcgtcaa atttccatgc atcataaact
     1201 ttaaccttat atattttgta ttgttcatca tcttttttgc gtttaaaaaa gctaactata
     1261 catccctctg tgggcaaccc tacagagcct gccacatttt ctactaccgc taatttttca
     1321 tttgtagttc ctgctccctt cttttttaag ttaatttttt gtttagtaaa tggtattttc
     1381 atcacataaa aatcatctct taataaatga ctttctttta tttcgtaaat ataaattcca
     1441 gtatattttt catcatcttc aacatatatt gcaatattgt acaataattt tccgttatca
     1501 accgctaatt caatattttc tagaaaatcc gcctcatcta aagaagacct tattttttct
     1561 aataagtcaa tatgatatgt tttttcatca ttttcgccta aacttataga atatttttta
     1621 ggattctcta aagattcagc taaatcaaaa tagttcttca ttccatattc tgaaatattc
     1681 ttaattgatt tagaaaaaga aactactttg tcattttcta tcgcaacttg ctttatatta
     1741 aagtcatttg tatcgttgaa atttagcaaa aatattttat ttatgttcat gtaatcacac
     1801 ctttttttca agaataattg ctacattatt agggtagttt ttatcaccta tcataatcac
     1861 atctactttt tttaaaataa tatcatcaat attttttgtc tttccaaaaa catactctat
     1921 acctcccaaa tcatatgtat caactttaaa aacagaatat cccataaaca ttaatgaaat
     1981 atttggaaaa aagtcggaag aatttttgta aaatacatat acgataaatt gaaaaagtaa
     2041 aataaatata atcatagtta atggattctc atcagctgaa aatgttgtta ttgcaggtac
     2101 aataaaacta agcagaaaat cccttaatcc accattatat tcattagaaa ttctaacact
     2161 attagtacct aatgctttag ttaatttctt ttggttattc aataactgaa taacacgaac
     2221 taacgaatat aaatctacta atattgacaa caacattatt aatattgtaa tttttgacga
     2281 ggtagatgac actttaaaca aattctcaca attgttattt tctagtttag aagaaaatat
     2341 aaatactaat actgagatat gtatcggaaa caacgaggac acataataat agagcttaaa
     2401 tttctcacta gaggatctaa acatagtttt ttaattgccc tcctttcttc aaaacattaa
     2461 acagtactaa atatacaata agtataacaa aatagtatta ctttttgtaa cacaaattta
     2521 atcaattaaa atctaaaaaa tgccactcct acaaagaagt gacaaagaca actatatacc
     2581 cgatatgcta tactagatag cgaaaaatta aaaagtaact tgcagaaaac gtttctttag
     2641 agagaaactc tggaagttat ctttataatg ataagttaga taactgttag atagtaaaac
     2701 ggttacttat agacaataaa aaatctcttc atttaaaagg agattctgca tttcttttta
     2761 ggataaattt aattaagctc tgttggacta atcactttta ttttagcttt cttataatct
     2821 ttaatatttc tcgttaaaat aaaatccacc ttgttagcga tggccgtttc aaccataaca
     2881 gcgtcctcat aatcagctac gtcagaagtg attgccatta tggtatcttt ttctttggta
     2941 tcaaggatct gatagactct acttaacttt aacaagactt ctttagtttt atcattatcg
     3001 tgtaatgaat gatgtacaat ataaaaaata tctgtcattg ccttagctgt cgtacaaata
     3061 gtatcgccct tccttattaa cttagaaaca gcgctataac tatcatcaac aaatttttct
     3121 ctatccaaaa gaatatcaat aataacacac gtatcaacta aaactttttt catcagatat
     3181 tactaatcct ttcacttctt agttcctcat ctgtcatatt catatctggt gcaattcctt
     3241 ttaagtcatc taacatttgc agtttacttt gatttggatt agataaaact gatacaatta
     3301 ctccattttt agtaatgtat atatcttcaa attctgactt ttttaaatac ttaccgagat
     3361 tattctttaa ttcagttgct gtaacttgtg tcatttaaac cacctccaca aattaattat
     3421 accacaaatt agctaatcat atagtaaaaa cagctaatat taaatataaa attagctaaa
     3481 tacgaattat attaactatt gcttaaaaac aacacccatc aaaaaaatcc catcagtatc
     3541 tactaccatg aactttttat ttatcaacat tacctctacc aataatatta agaataaaac
     3601 caaatacttt ccatgataat aacttccttt gtataatgtg atgttgctat attcattaat
     3661 gcaactacat taattttttt gaattgatat atactaaaaa atattataat tcctattgat
     3721 aaaaagaaaa aatctaatat ttcaaaattt aaattatctc caccctcatc ttaaaaagag
     3781 ctgaagatat tccagctctc acaaatattt tatccagtaa aggcgtacaa attaatctat
     3841 ctattaaaca acttatcctt ataatattca aaaaatgttg tcttacctgt aattacaacc
     3901 atttgccctt gcataccata cttcaataaa tccctattgg tattttgaat atctgtttta
     3961 gcttcaattt gataataatt ttctttccct atctctactg gagaaatcga tatcttatgt
     4021 atttttccag tcaaaataat aggtttaggt acatttctag ttactttgaa tcttactttt
     4081 tgccctactt ttatggaaga aatatctgct gtacttatat atgcctttat ctttaaagtt
     4141 ttttgattct tcaaaatcgg cagtatctga gctaaattag cccctgcact tatataatga
     4201 ctttcactat actcatcgtt aatatgtaaa attccgtctc taacagcctt taccttatac
     4261 tctctattag tattattatt ttcatcaata ttagcgttca attctgatat attttgcttg
     4321 atttttataa tttcttgatc aatagaactt aacttacttg actgtaaatc actcattttt
     4381 tgattgttta tatcaatatc gtatttagac gaatcaaaat cagctatact tgtagcagac
     4441 ccaccttgtt tcttcaactc gttattaatc gaactttgtt tggctttatc gtttttagat
     4501 ttatcctgga tcattgtatt ttctgttaaa tacgtattcc tttgttgtag gtaactcttt
     4561 aaatcattac ggtaaccaaa ttcatcatct tccccaaaag aatcatgatt gtcttgaaca
     4621 ccttgtttaa gtaagttcaa agctgccaac tgtctatcta agatttcttt ttgtgaatta
     4681 tacagtttcc ccttatcttg tatattcaca ttattataaa caagtaatgt atctcctttt
     4741 tttacatact ttccttcttt taaataattt ttttcaatag gactatttac agttgattga
     4801 ataacaggat tatttcccaa tgcctcaagc gttcctgcac cttggatagt tatctccttt
     4861 tttccaaaaa agctaaaaat tactaccgcc aacaataaaa ttgtaaaagg aataataatc
     4921 atagttgaaa agtttctaaa tctagctgaa taaaattcgc tactttctaa aaatttatct
     4981 tccataatac aatactcccc ctaactatta attaaattgt agtaatatcc ttttttagct
     5041 aataattcat catgtctacc cttttctaca atttttccgc catctaatac tagaatatta
     5101 tttgttcgct tagctataga taatctatgt gcgataaaaa ttatagtttt tgactttaat
     5161 ttcattaaat tatcaattag ttttttctcc gtaatggcat ctaattcact tgtagattca
     5221 tcaaaaatta atacttgtgc tggagataat aaggctctag caattgtaat tctttgtttt
     5281 tgtccacctg ataagatatt agcattttca tctagtttag ttttcaattg tagtggcatc
     5341 ttcgctatat ctgtatcaat cattgctatt ttacaagcca tgagaatatc ctcatcagtt
     5401 acattagatc gattacctag tctaagatta tcttctattg tcccagcaaa aatatatgga
     5461 ttctgtggta tgtaattaat ataagaacgc agagtatgct tatcaatgtt atttatatca
     5521 tgattattta gttttatact acctgaaact ggggcaaaaa aattcaccaa tagtttaact
     5581 aacgttgatt tgccagagcc actcatacct actatagtta gtttttctcc ctgttttaaa
     5641 gtcaaattaa ccttatccaa aatattttca ccatatccat agcgatagtc aacatcttga
     5701 aatataatat ttccttgaag ttgagtgaca tcatgaacag cttttctatc tttaaattca
     5761 ctttcaacta agtaaacctc attcaaacga ttgtgagcta cccttgcact ctgcaatttt
     5821 ggctgtaaat ttatgatatt ttgtaacgga ttcacaaaat aacttaatag tgcgttaaaa
     5881 gtcattaatt gtcctataga gagttgatta ctaattacca gatttgcccc taaccatagg
     5941 actataacat ttaatgtttg ttgaataaat aactttagtg cttgttgcaa cgagtctgtt
     6001 tttatatatg ctaacgattt acgcaaatag tccacaaatt gactatcaat tttgcgataa
     6061 cgcatttgtt cgctgtttaa ggcttttatt gtttctattc cttgaatatc ttcaataata
     6121 gatgaactaa gtatcgcatt actttccatt tgtttattat tcaatctttc aaatgctttt
     6181 gtaaatgtaa gaataataat cgtgtaaatt ggaagtgaga taagagttat ccctaataat
     6241 ttaagatttt gaatagccaa gattattccc ataataacca caatgcttac atctaaaaaa
     6301 atagatacta cagtgcttgc taaagcatct ataattttac tagcatcatt aaaacgagag
     6361 actatttccc cagtttttct ggtcgcaaaa aattccatag gcaactcaaa aatatgtcta
     6421 atataactta aaataatttc aatcaaaagt cgttgtccta aaattgctaa taaaaaatcc
     6481 cttgcatatg taaaaattga attgaacaca tatattacta gtaatccaaa agcaataatt
     6541 gccagtgtac tatgcatacc attaggaata tatgtatcaa ttattccctg taaaaaatat
     6601 gatcccaata tactaataat tgtaattaac aaagctgcca atacaatatt aactattagt
     6661 tgcttttgct taaataattt actaaatagt gatattaatg attgtctagt ctcttttgtc
     6721 ggcttatatt caattcctgg aacgatgaat aaagtaattc ctgtccattc tttttcaaaa
     6781 cgttcatacg acattttagt tatccctaca tctggagctg gatcagcaat taaaatataa
     6841 ttaggtgttg ctttcaatac tacataataa tgtaataacg tctcttcttt aaccacatgt
     6901 acaataaatg gatatgtaat gtctttcatt ccaaaaagag acatatcagc ttttacggct
     6961 tgtgtttcca ttcctaaagt ctgtgctgtc ttaacaagac ctaaagctgt agtcccctcc
     7021 attgttgtct tagcaatgtt tcttaaatac gctaatgata gcgatgatcc atagtgtttc
     7081 aaaatcatag ccaacgaagc tacgccacaa tcagactcgt ctacttgtgg gatataatat
     7141 tttttgtatt tatgtatcat aagttaatat ccccctatta aacttattat ctttcatctc
     7201 ttttattaag catatcatgt tcttaaatta tcttgcctaa atcatcaaat ctggtccttt
     7261 ttatacttat ttggtattag tattttcttt aacttgttaa aataaaaagc taaaaaaatc
     7321 attgagtaaa ttttaatttg atttttccta gctttcttaa tttattaatt ttaacgattt
     7381 ctttcataac gctttgttag caccaatgat tgatagacat attttatacc taggcaagta
     7441 aataatatgt caataattgt aaataaaaaa tatcctttat caagaaaaat acttcctacc
     7501 gctattgata acattactaa accgatataa aaagtataat ttttataaaa ctttttattt
     7561 attttcatat actactcccc atttccacta ataatttcag ctagattttt ccattataca
     7621 atttcatttc ctagccttaa tttatcatat tcttaaatca ttgtgtctaa attatcaaat
     7681 ttggtctttt tttagattta tttggatact aaaagtgttg ttaaaatgta gattagtcaa
     7741 taatcatttg caaagataat catgaatgtc atataaagag gattggaata ccctaagttc
     7801 caaccctctt tattaactat attttctatt ttgtctaatt tctttaatca acataatcac
     7861 aaaaatcatc aatgttccca ataagattaa acctcttact gttaacatag gagttcgcat
     7921 aagtccattt agatccagta atattaacaa taaaaagcct gcatatctac tattttttgt
     7981 aaaatttact ttcaaccttg aaattaccat aaaccctaca actagtaata tgataatacc
     8041 tatttctacc atgtcatttt caccacttat atcaataaaa acaaaagatt aaactgtttt
     8101 caaattatac ctttcaatca aacttttcat tttagcctta cttcttctag gaaaagtctc
     8161 tttatatcca tctttaaaag aaataaccct tgttgacagg ttaatttcaa caatattact
     8221 tggattagct aaacaagatt gtgatatttt ttctagaaaa tcattttctg cctctaactt
     8281 cttaatatcg cctgtaaact cacccatacc attaactgta actatttcta atctatgtga
     8341 cttaggagtg gtaataatat atagaatatc attaatattt tcgttaataa ttcttctgcc
     8401 cattttatag ctaaatgtca ttttctttat ggcatgagat tccctaattc tccttgcagc
     8461 taatgataaa gtctcattta gtcgcttttg aatcacttca tcactatcat ttttagtaat
     8521 aaaatctaac gctcctgtgc gacgtcgata ggtcattgct gctagatttt cataagctgt
     8581 aataaaaatt atctgtgcat ttggatctct ttgtctaata aattcagcta agtctattcc
     8641 atctctatct gctttatccc tactaagctc gatatctaaa aaataaactc cactatctac
     8701 tttattatct tctaaatagt cagctacttc aatataacta ttagcttcca aagttatttt
     8761 aaactcttta tctttactgt cagcagaatc ttctaaagac caaatagcat atttaactaa
     8821 atcatgtatc cttctaactt gatccttctc atcgtcacaa ataataattc catattcttc
     8881 caaattaaac taccccttaa atactcataa ccataaggaa agtaaaccag ccatctttaa
     8941 tttgataatt gataaaaata tcattataag gttgacttaa ttcttctata ttagctaatc
     9001 ctaatccatc atgattcttc ttagttgtaa aacccgattt tttcatatct tgaattgtta
     9061 agtctgtatt tcgacaacga ttcttaattt ctatttcaag ctcaccattc tctcgataaa
     9121 ccattgtatc tatcctagct tcatcgccaa gttcaagact ttcttcaatt gcattatcat
     9181 acgtaatccc taatattcta attatatcaa atgcattata ctcattcgat aaactatcta
     9241 tcacatcccg acattcaaaa gagtattgaa tattatcttg aaagattcta ttcaatttac
     9301 tgataaatag actctttaat aattcatctt taatgttgtc aacatcatta aactgccata
     9361 atactttatc ttctaagatc ttactcgaat attcagctag tttatctatt aactctttat
     9421 catgattttt ctttgcactg agcttcaaac ttactaacat attttggtag tcatgcttaa
     9481 atttgcgtaa acttcgctgg ctactttcta actgttgagt gtaaatcttt aaatctttaa
     9541 tttgctgtaa acttaattta tcttgtctaa tttttttact attattgtag atatatagtg
     9601 agaaaattaa ttgtacgata ataactacta ataatataag atataacacc ttatcaactt
     9661 taaataaata accagtcaaa taatatattc ctgcaaaact gactaataaa taaataatta
     9721 aatagaagaa tgtctttcca tattcatcat ctaaattctt tataatatct gttttcatta
     9781 aaatatagta ttctaaaata tttataacaa tagtgtctat tggaagtgtg ctgatgtatt
     9841 gtgaaattat ttgtgaaagt aaaaattcta tctcaaatga aagatatgaa tatagtagga
     9901 gaattaatat tcttcccaat acttgataat ctctttttct tcttttatat actatataaa
     9961 aagccgatac ttcaaaaagt tcggcacaaa aagcacctaa atctccaccc ccatgataca
    10021 aaaaaactat cggaaatgta ataattgtaa atagaatatt ttgcttttta cttctattaa
    10081 tgggtgtaat taaatagaaa aatagatagt cacatgctac actaataaat aaaccaactg
    10141 catatattat aatattatat ctattatata tatccactat atctgtcatt ttacttgcaa
    10201 attcctaaaa atttaaacct acatacttta tcataagttt ttgttcctcc ctcttgttta
    10261 ccacctacaa taacttgtaa cttcttttct gttaacactt caaatttcat aaaaaatctc
    10321 tcctttgtta tctttattac aagtatagtt taacattttt taatctactt tattcgtttt
    10381 ttatcatatc cggttcattt taatgcttat ttggatgaaa ttcttaaaac tatagctatc
    10441 atataaagtt taacacccat accctcataa cttatttttt tattgtattt tttcttttat
    10501 caaataacct gtaatgtcca tcttcttttt cactagtata gatactgata aagatactat
    10561 atgccactat tactgtaacc caaaatatca tgtactcact tcctaatccc aaaatatatt
    10621 gtattctatt aaaaataaaa gtagtgtcaa atttagctat atactataac ttacacttga
    10681 cactacttgc agaaaaatag attttttcta atttttttag atctatctta atggcaactt
    10741 gcaaatccac cagaaattcc acccgctacg gctgaccaag gtccaccgat agctccaatt
    10801 aaagctccac ctacgatacc agctccacag tgaacccagc gatttccgct accaccataa
    10861 ccatttttac caccatttac tgatgctaag ttatcttcag tcataattgt gaatctttta
    10921 tctagatttt tcatcttaaa tcacccctat attataaaca agtaagcgct ccgcctacca
    10981 ttcctaagtt tgctccacct acaataccag ctggtccaag tggaactcct gcagctgctc
    11041 cagcaaatag accacctaag aagttaccta cacagttagg tccacgtttc ccaccatcaa
    11101 cctttgctaa ttcacattct gtcaatactg taaattcctt catcatgata atcatccttt
    11161 catatgttta tttaccttca ttgtagtatc taataaataa agtagtgtac taccacctat
    11221 tagacaaaaa atagcaacta ttatcatttt aggcgtctgg atataatcta aataagacat
    11281 gtcctcatta ccaaacaacc atattcctag tggaatcaat agtgcccaaa taactggagc
    11341 aataacatat ctcttctttc ctctaatgaa tccaccatcc aaccaagtct cccatagttt
    11401 ttttagcatg taaaaacaca tcctttctaa aacacttgtg aaacatatac ttacactttt
    11461 attgtattat cattctgtat tcaaatatca atttagcgta aaatacgtta ttctatacct
    11521 agttggttac atttcttttt aactacaaat attttgattt gaatgtctca atcttttgaa
    11581 aaatttggta ttagcgattg tacatcctat atcataacca aacttaccac tatctatata
    11641 gtcataagaa tttcttccac caattatatg tgccaattct ttcttatcaa tttgtacaaa
    11701 attattattc ataacttcaa cacctcataa tttttaaaaa tttattatag ctataattta
    11761 cacttatgat tattcacttc atctgctctt tttgattatt tcttctaatt ttgctaaatt
    11821 ttattcttat tctctttttt caaccagata ggcactattt attaccaaat tggaaaaatc
    11881 tcctcaattt attactttct atgtaataat aaaaatactt ttataatgaa ttgaggtaaa
    11941 aattatgaat agtttttcta ataatattaa tttcagcaaa atttctgttt cactaattac
    12001 tttattccta ttgatctgga cattagttga tggaaatcta attcatcttg gtatactagc
    12061 cttttcttct ttggttacaa ccatgctaca tttccattat tttgaagcta ctgatgacaa
    12121 gcatccacta aatagaattg attttggatt acaattgcta tttatcttta tttctattat
    12181 taaatttttc ttgatttcag gaagataaca ataagcctat caggtatcaa attacatctg
    12241 ataggcttat ttattaacat atgtatcaac aattttgtac ttctttttaa attttctttc
    12301 tgatataatt tttcgattag tgaaatccaa gtaatcgcct atatacccac ttgcataagt
    12361 tgcccaccaa cctgaagctc cattaaataa agtcttaaag ttcgtccaag cactaatttt
    12421 aacaggtgcc ttaactccat tcataataaa taacaattta tcacctgacc actttagata
    12481 gttagcttta aatgctgctt ttatccattc gggttgttct gctgttttac ttatctgcca
    12541 tatttgtact tctttacctt tatagattgc tttcatagaa atcaccttct acatataatt
    12601 aaagagctct attaattaca tcttcattat actattttca taatacatcc aatgctaaat
    12661 ttcttaacta gcactatttc ttacttattt ggtaaatagt ccaaataagt agttattgct
    12721 accattccag cagtttatca cacatgtaga cattatttgc aataattaca tatatacgat
    12781 taggggggat tgaaaaaatg agatacatta aatttacttt actaatatat tcttttttac
    12841 taacttgggg aatcaccacg aatagtatat cagcggatga agttacacct actacaacat
    12901 ccgaaacaat agttacgcct caaagtcaaa gtacacctgt tgattctaat gatgaagatg
    12961 ctgtaattga agaaaaattt tactctcatg atgttacaat cgacgaatat aatgaaaatg
    13021 tagcgaactt caataaagtt aatactgata ctgttaaaac catgattact gaaaatagca
    13081 acaatttaga ccaggttctc tacattggac gtcctacttg ctatttttgt cgtcaagctt
    13141 caccacacct acgtgatttt aatcaactaa taaataatca gctttactac tatgatattg
    13201 atactgaacc taatgctcat gattttgcgt ttaaagaaat tggaattcct ggaacaccta
    13261 caactattcg tttgaagaat ggtaaggtta ttagtgcttg gattggtggc gaaaaaacag
    13321 gacaagaatt ttatgacttt ttattttctg cagatgctaa caagttagca aattcctata
    13381 ccataaagaa aactgtaagc acagatactt caaatcctgt tattacaaat aatcaaaata
    13441 tcgaaccaat tgttaagcct atatcaacaa acataagcca acttaaagag gaaaaaaata
    13501 ctactgaatt ggttaatact acttcacaac catttaaacc tgttaaaaaa attcagaatc
    13561 cagctacaac tactaataag aaaaacaaaa attctgttct accacagtta ggggctgtcc
    13621 ctccttatca tcagccacta tttaaacttc ctattccccg acttattcct aagcgactag
    13681 aacgtattat agcgttggtc tcttttctag ttctatatat tggtatcact atatggacag
    13741 ggttgagttt aaaaaattgg gataaaaaat aaaatatcta atatagcaat aggaccaatt
    13801 agaaaattta tgcaaataat tgatttagaa aaatcaatta tttgcataaa ttttctaatt
    13861 ggtcctatct ttatatttaa cttttttcaa aatttgcaac tttatttctc atattaattt
    13921 ttggggctaa cttcaaataa tatgctgttt actcttcaga cactacccga tacttcttag
    13981 caaacttttc ggctgtaaca accttagaat tggtaaaatc gataacatct ccctcaaagc
    14041 caatatcata catcgacgcg ctgccaccat ttatactaac aagagaagct gaaataccat
    14101 tcaaaatagt tcgtattatt cctttttttg ccctagtaac tgccggccaa taaattctga
    14161 ctttattacc actaccatgc agccatcgta atccattatg ctcaaaagca tattttaccc
    14221 aatcaggttg gacattatct ctactcactt gccaaacatc tacctttcta cctctataga
    14281 ttactttcat ttgctttatc acctttctta ttattttttc ctatccttaa tagccataac
    14341 taatctatac atcactaaga ctatatagac caacaatgct attaatacta tcgtatatag
    14401 tattttattt tcatagcctt catcaaatat tgtagttact attagaaata ttcctaatgt
    14461 tgcttgtttt ctagctcgtt tatctaattc accatatttt ttcttataat taacttccaa
    14521 aattgctgat agtataaaga atatccaaat aattgcctta ataactaaat aatccatcat
    14581 tccaccatct attctctatt tttgccatta ttatactatt ttaattaaat ttaattctgt
    14641 attttcttaa ttaacactct tttctgctta tttggttcat atccatgtac gttaaaaaaa
    14701 tagcgacaaa aacatcgctg tcttgccact attcccaact atttaaataa attaagcttt
    14761 gcgattctat cgactgcttc ttccaaacgt tctggttcaa ttaacaaacc aattcgtaca
    14821 taaccttctc catattcacc aaaaccattc ccaggagcta ctgctactcc agcttcattc
    14881 aaaagtagat ctgcaaattc ttcactacta tatccctttg gtacttccat ccaagcatag
    14941 aaagttccct taggtacaaa agctttccat ccaatttttt cagcagcttg gatgaacgca
    15001 tttcttctag tttcgtaacg atctacaatc ttattgatct cggcatcgcg ttctggagct
    15061 ttcaaagcat caattcctgc atattgtaga gctggaaaga tacttacaaa taaatggtct
    15121 tggataagat ttaaagcatc aatgatatca gcatttccta ccgcaaaagc gactcgccag
    15181 cctgccatat taaaagtctt agagaaggta taaaattcga tgccgacatc cttagctccc
    15241 ggaatctcca taaaacttag tggttgctct ccatcaaaac caattgcacc ataagcgaaa
    15301 tcgctgatga tacctacttc atatttcttt gcccaagcga ctaattcttc gtaaaattct
    15361 cgggttgcag tcgcacctgt cggattatta ggatagttaa tatagaaaaa tttagctttt
    15421 ttggcaagtt cttcaggaat agatttcaaa tctggtaaga aattattctc cttcaaaagt
    15481 ggaactttct caaaagttac ctgtccaagt gtagctccag accaataatc tggataacca
    15541 ggatcaggta ataaaaatac atcgccagga ttcatcaatg ctagtggtag ttcgactaaa
    15601 ccagttttag aaccaccaag aactgcaact tctttttctg gatcaaatgt agtttgatac
    15661 ttttcttgat agaagtctgc cacagcttgt ttaaattctg gctgtccacg aaacaatgag
    15721 tacttgtgac tttgcggact agctacccat ctttgtgtgc tcttgacgat atattcagga
    15781 gtttgtttat caggattacc ttgtcctaga ttgataacat ctactccttc tgcaattttt
    15841 ttgttaactt tgattaccaa attagcaaag aattgctttg gtagattctt tagaatttcg
    15901 gatttctcaa attccatcgt ctttcctcgc tttcttagtc gtataattct ggtctacgat
    15961 cttcaaatac atgaatttgt tgagtgaatt tttccatttc ggatgtatct aaatcataaa
    16021 ctgtcaatgt ttcttgatcg ccactatcac ttaaaacttc acctaaagga ttaattatca
    16081 gtgaatgacc attaaattta ttgtcaggat tatcgcccac tcgattaact gcaacaacat
    16141 aagctt
//
