LOCUS       c00045_gnlPro..        11993 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BGKKHJAO_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 06:46:13
            Original ID  :: gnl|Prokka|BGKKHJAO_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11993
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11993
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1118:1993]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1119..1993
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..11993
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /kind="single"
                     /product="Arginine2putrescine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11993
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2putrescine"
                     /region_number="1"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /tool="gutsmash"
     CDS             complement(2..1030)
                     /locus_tag="ctg45_1"
                     /transl_table=11
                     /translation="MFDIILKRKEGTNVLKGIKLRLYPNRTQQNQLEQMFGNDRFVWNQ
                     MLAMMNERYQNNKALPFLGKFKLNYLLKPLKKEYPFLKNSDSSSLQVVNEFLTQSWKNF
                     FQDKTGQIGKPRFHSRKYLKKSYTGKSIIKTAGKRYLKIPKLGYVKTSKTGVLQNTKIK
                     RYTVVLEPTGKYYLSLQVEISEPEKYSLTGKQVGIDVGVADLAILSNGLKYPSFDSSYF
                     EKKAKIWQKKYSRRRHLVKLLVLQNKNKRVLCPRSLESFTNWQKAQKSKAKCQAKAANQ
                     RRDYLHKLTTHLVKQYDVIIIEDLKTKNLQKNHHLAKSIANASWRMFRQMLEYKCEWYG
                     KKL"
     CDS             complement(1119..1316)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_2"
                     /sec_met_domain="Amidinotransf (E-value: 4.9e-19, bitscore:
                     58.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLAIGISQRTSAAAITDLAHSLFGHSSYDTILAIKIPHNHAMMH
                     LDTVFTMINYDQCTVHPFID"
     CDS             complement(1323..1658)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_3"
                     /sec_met_domain="Amidinotransf (E-value: 2.1e-26, bitscore:
                     82.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVNEMVKQIIAGIRKNEIQNATPSLADLAEDPDYPFYLDPMPNV
                     YFTRDQQAAIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWRDRYTHGRLE
                     GGDELIF"
     CDS             complement(1808..1993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_4"
                     /sec_met_domain="Amidinotransf (E-value: 1.4e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             complement(2066..2920)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     71.2; E-value: 1.7e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg45_5"
                     /sec_met_domain="LysR_substrate (E-value: 1.7e-31,
                     bitscore: 99.4, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 4.7e-23, bitscore: 71.2,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVAAEEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTADPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKHSNWITHLQLVWRKDQKVTPLMKRIIDS
                     LSR"
     CDS             3049..5322
                     /locus_tag="ctg45_6"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSDLSDLPDKDVLALAGSATDKRNAGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(5390..5890)
                     /locus_tag="ctg45_7"
                     /transl_table=11
                     /translation="MMRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTR
                     NATVYNRHGVKVGQLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVV
                     NRIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTV
                     TNH"
     CDS             6029..7516
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_8"
                     /sec_met_domain="PLDc_2 (E-value: 3.3e-27, bitscore: 85.2,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILTWDIIRRTIEVLWIINIAFAVWTVFRSRRSVVATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQRDMLKEHDLLPEKERLPRV
                     RMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKNAKKSVSLEFYTFYSNQLGH
                     RVLKALEEAAANGAKVRVIYDTSGSRGTKPSFFDHLRELGGEAQPFISTSKKHWFTTPR
                     LNYHLHRKLVIIDHHIGYIGGFNIGDQYVNKSPKFGHWRDTHLRVIGQSPILMEVRFAM
                     DWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQLFPQDLIINITASDEAEGIIA
                     GAKKYIYIQTPYLIPEESILEALIIAANSGIDVRIMVPCMPDHPFVYRATEYYAKYLVA
                     HGVKVYKYNDGFIHAKTMVSGSNISSVGSANQDFRSYTLNFEVNSFNYNPALTQELKKI
                     FEKDLGKCTLLTNDYFAQQSSWLKFKQYFSRLLSPIF"
     CDS             7644..8438
                     /locus_tag="ctg45_9"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             8454..9383
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_10"
                     /sec_met_domain="PALP (E-value: 7.4e-69, bitscore: 222.5,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPNDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEKLVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(9527..10072)
                     /locus_tag="ctg45_11"
                     /transl_table=11
                     /translation="MEVFLLMAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIAT
                     HELAEYAKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEY
                     GSNSLEMHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKG
                     REKLPDVDIYSLVQYHGA"
ORIGIN
        1 ttagtttctt gccataccat tcgcatttgt attctagcat ttgtctaaac attcgccatg
       61 aagcattggc aattgactta gccaaatgat gatttttctg aagattcttg gttttcaaat
      121 cttcaatgat aattacatca tattgcttaa ctaaatgcgt agttagttta tgcagataat
      181 ctctgcgctg attagctgct ttagcttggc acttagcttt tgacttttgc gctttttgcc
      241 aattagtaaa gctttctaaa cttctaggac aaagcaccct tttattctta ttttgtaaaa
      301 ctagtaattt aactaaatgt ctacgtcgag aatacttttt ctgccaaatt ttagctttct
      361 tttcaaaata agaactgtca aaactaggat attttagccc attagacaga atcgctaaat
      421 ctgctacgcc aacatcaatt ccaacctgtt tgccagttaa gctgtacttc tctggttcag
      481 atatttctac ctgtagagac aaataatatt ttcctgttgg ttcaagtacg accgtataac
      541 gcttaatctt agtgttttgc aaaactccag tcttgctggt tttgacatag cctaatttag
      601 gaatcttcaa gtacctttta cctgcagttt ttatgattga cttgcctgta taagactttt
      661 tcagatactt gcgtgaatga aaacgaggct tgccaatttg accagtttta tcttgaaaga
      721 agttcttcca agattgagtt aggaattcat taactacctg caagcttgaa gaatcgctgt
      781 ttttcaaaaa aggatattct tttttaagcg gcttaagcag ataattcagc ttgaacttgc
      841 ctaaaaaagg caaagcttta ttattctgat agcgctcatt catcatggcc agcatttgat
      901 tccaaacaaa acgatcattg ccaaacatct gctcaagctg gttttgttgt gttctattag
      961 gatagagtct taatttgatc ccttttagca catttgttcc ctcctttctt tttaagatta
     1021 tatcaaacat atgtttaaga aagaaggggg gaacaagcaa aaaaactaaa aaaggccgga
     1081 ttcatcacgg gattaaaatc ccgtgttttc ttcggcaatt aatcaataaa aggatgaacg
     1141 gtacactgat cataattaat cattgtaaag actgtatcca gatgcatcat ggcatgatta
     1201 tgtggtattt taattgctaa aattgtgtca taactagaat gaccaaacag gctatgagca
     1261 aggtcagtga ttgcggcagc ggaagttctt tgagaaatac cgattgctaa aaacatgatt
     1321 gtttaaaaaa tcagctcatc gccaccttct aaacgtccat gagtgtaacg atcacgccaa
     1381 ataggaatat tggcattttt aaagtcggga tgatgcttta aaacggtttc cataaataat
     1441 gactcacgtc ttctagctct aaatgtcatt ctattaatag tcatgccatt accaatagct
     1501 gcttgttgat cacgagtaaa atacacattt ggcattggat ccaaataaaa tggataatct
     1561 ggatcttcag ctagatcggc taatgaagga gttgcatttt gtatttcatt ttttctaata
     1621 ccagcaatta tttgcttaac catttcattt actggcattg ctattaaata gtctatcagt
     1681 aattgatgta atggatcttc ttttttatat tggattcttc taataattga tctacaaatt
     1741 ttgtacggac atcttcatta gtcaaagagt gagctaataa atcttctaaa taaacgacat
     1801 gaactcccta tttttccaaa gtgtgggcaa aatagtcatg ctctttttga gctattttta
     1861 aatatggaat atcgtcaatt aacattcgat ttaagatatc cggtgaaaga ttttctaatt
     1921 ctcttcccgg tcgatgcagc ataactgttt ctaatttgcc aatttcggaa taaacatgaa
     1981 ttaagtcagt cattatagcg tctcctaatt caaattatgt atccgcttac aatgattatg
     2041 gatcaattag gtagaagtta caatcttaac ggcttagtga atctattatt cttttcatta
     2101 aaggcgtcac cttttgatcc ttgcgccaca ctaattgcaa atgcgtaatc caattactat
     2161 gtttaatagg aataagatca tcaggtgcat acgtagaagc aatagattca ggaacaagag
     2221 caatccccat ttttctcttc gcccaagtaa tcgctgttct agaatcatca catttaacag
     2281 cataaaacgg cttaatccca tgatgagcaa aagtctggtt aaaaatttct tcaaatcttc
     2341 gataaataat gaggggctgc tcatttagat ctttaatcct taattccgtc ttatccttaa
     2401 atttgggatc agcagtaact gccatcattc tttcagtagt taaagttttt gcatttaagc
     2461 cattacgatt ataaggcgta cgcacaattc ctaaatcgat tgtcttcttt tccaatttat
     2521 cgataatgcc aaaggtatta tcttcataaa tatcaaagtt gatttccgga taaaacttag
     2581 ttaaatcttg aaaacttttc ataggaatta gtccagttga tgatgaagcc atgcctattg
     2641 caatcgtgcc tagttcacct gaaacagttt tatgaacctg atttttcacg ctttctgata
     2701 aagagagaat ttcactagca tagctctgca aaatttgtcc agcatctgtt aattcaattc
     2761 catgagcagt acgcttaaat aattgtgctc ctaattctat ttctagttgc tttaattgat
     2821 aactcagcgg cggttgtgca atgtatagtc ttttagctgc tgaagtgatt tgcttttctt
     2881 cggctgctac taaaaagtag cgtaattgtt taatattcat taataattta tcttttttat
     2941 tttagttgta tctcttatta aaaatttcta tatcttatat tttaatttag tattttcatt
     3001 caaacaacat atgtgctact ttattaaggt agatttggag ggaataaaat gtctgaaaaa
     3061 tttcatggct taactcaagc cgaagcagat aagagactta aggaagatgg gttaaacgaa
     3121 gcacctgaac ccgaatacaa cttttttaag gaatttctat caaaattatg gaatctttct
     3181 gcctgggttc tagaaggtgc cttaatcctc gaatgtatct taggcaaatg gattcaatct
     3241 ttgttcgtct tgttgatgct tctttttgcg gcttttaacg gtgcatccaa gaagaaacag
     3301 tcacggcggg tattaaatac catttcacat aagctaaccc ctaaggtggc tgtagaacgc
     3361 gatggtaagt ggatcaaaat tgactctaag caattagtta gaggcgactt aatctcactt
     3421 caacgtggag atgtacttgc agccgatgta aaaatggtta gcggtaagat cgcctgtgat
     3481 gaaagctcaa ttaccggtga atctaagccc gttaaaaaga acattgatga cacagcttat
     3541 gctggtacta ctgttgttga aggcgatgga ttagcaattg ttactgcaac tggtaaagat
     3601 tcaagaagtg gtaagaccat taacttgatc aacaattcag ctgcacctgg tcacttgcaa
     3661 caacttttaa ctaagattat ttactacctt tgcctacttg acggtgtact taccttagtt
     3721 attatcattg cttcattctt taagggtggt aattttgata cgtttatcaa catgttgcca
     3781 ttcttagcca tgatgttcat cgcttcaatt ccggttgcga tgccgtcaac ctttgcattg
     3841 tccaattcat ttgaagcaac ccgtttaagt aaagaaggcg tcttaacagc tgatttaact
     3901 ggtatccaag atgcagctaa cttaaacttg cttttacttg ataagacggg aacaatcact
     3961 gaaaataaaa ctgcagttgc tagttggagc gatttaagcg atttgccaga taaagatgta
     4021 cttgctttag ccggtagtgc aactgataag cgcaatgcag gtatcattga tatcgccatt
     4081 gatgaatact taaaagaaaa caatatccct gtcatggacg ttgaacactt taccccattt
     4141 acttctgaca ctggctattc tatggctgaa gtagatggtc acaatgttaa gttaggttca
     4201 tttaagcaac tttcattaat cgataagaat gcaaatgaag cagttgaagg catcaatttt
     4261 aaagctggac gctcagttgc cgtgttaatt gatgacaaac ttgcgggagt atttatctta
     4321 caagataaag taagaaagga ctctaaggct gctttagcag aacttaaaaa acggggcgta
     4381 cgtccaatca tgttaactgg tgataatcaa agaactgccg cagcagtcgc tgaacaagtt
     4441 gatttaactg gtaacgttat ctctattcat gactttgatg aaagcaccga tattgatgaa
     4501 ttagcaggaa ttgccgatgt tttacctgaa gataaactta agatggttaa attcttccaa
     4561 gaaaaaggtt atatcgttgg tatgactggt gatggtgtta acgactctcc tgctttaaag
     4621 caagctgaag ttggtattgc tgtttctaac gctgccgatg ttgccaagcg ttcaagtaag
     4681 atggtgcttc tagatgatgg cttaagctct attgttaaaa ttcttgatgc tggtcaccgt
     4741 gtatatcaac gaatgactac ttggtcactt gctaagctcg ccagaaccgc cgaattaact
     4801 atgcttttaa ccttcggcta tctcttcttc aactatattc caatggcatt aaatgctatg
     4861 gttatttaca caatcatgaa taacatggtt accatgatga ttggtaccga ccgtacccat
     4921 attacttaca aaccagaaaa ttggaatatg gcaaggttag ccaaaatcgc attctctctt
     4981 gctgcaggtt ggacagttat cggtatcgct tttttcagct acctcaacat gcatggctgg
     5041 agtcacaatt ctatctctac catggtctat gtttacttag ttctaagtgc aatgttaatt
     5101 gtattaatta ctagaactcg taaatacttc tggcaagatt acccatctaa acttgtaggt
     5161 attgttcaaa ttgccgatgt cgcattaacc tttattttag ctttatgcgg tttagcaatg
     5221 gctcaaatta gttggcaaaa cttattaatt accgttgtgg ttgcattaat tgcagcaatt
     5281 attattgatt tgatttatca accagtaatg aaaaacagat aattaactta aaacaaaaac
     5341 actctgaaaa ctacattgta gtaatgtagt tttcagagtg tttttttgat taatgattag
     5401 taactgtagt caaggcattc aaagccttaa catattcacc atcagcaatt ttgataaatg
     5461 gtttttcatt aatttcttta tggcctaaat agttaacctt agcaccacgc tttaaaaatt
     5521 tgcctgggat tttttcacca ttctcatcat aaacaaagga atgctttttg attctattaa
     5581 ctacttttac agtagtcttc atatatggca agaaggcttc ttccttaaca aatctatttt
     5641 tacgaatctt tacataagta ttaccattaa ttacttttat ggcacgtact ttgtaaagct
     5701 ttccctttct taattgtcca actttaacac catgtctatt ataaacagta gcatttctag
     5761 ttagatttaa tctcttacct tgtctaactg gattagtaac aactgcatca acgctttgtg
     5821 tagttgctgc gcctaatcca ataactgcta acattatacc tgcagcagaa ataatttgtt
     5881 ttctcatcat aatccacccc cgtagtgttt ataccattct ccatccctta ttttatcaaa
     5941 aattatcgaa ttggaagcat tttttactca tctgttttat aactatttgc ttaattctgc
     6001 taaaattatt tataacacta cttaattcat gattttaact tgggatataa tccgtaggac
     6061 tatcgaagtc ttatggatta tcaatattgc gtttgctgta tggacggtct ttagaagtcg
     6121 ccgcagcgtt gttgcaactt gggcatggat gcttgtatta accgttctgc ccggtatcgg
     6181 ttttatccta tatcttttct ttggtcgtca gctttcacat gatgaaatct ttgctattca
     6241 agaagagcaa aaaaaggtac aaagacatta tttagctgag caacgcgaca tgcttaaaga
     6301 gcacgatctt ctacctgaaa aagagcgtct tccacgagta agaatgcttt cggaactaaa
     6361 tcttaacaac gatgatgcga ttttaacttt tgataatcag gtcaaagtat ttatttctgg
     6421 accagaactt tttgaccaaa tgattactga tatcaaaaat gccaaaaaat ctgtcagctt
     6481 agaattttat actttttatt ctaaccaatt agggcatcgt gttttaaaag ccttggaaga
     6541 ggctgcagct aatggtgcta aggtaagagt aatttatgat acctctggat caagaggcac
     6601 taagccaagc ttttttgacc atttaagaga attgggcggc gaagctcagc catttatttc
     6661 cacttcaaaa aagcactggt ttactacccc acgactcaat taccacttac atagaaaatt
     6721 agttattatt gaccaccata ttggctatat tggcggattt aatattggag atcaatatgt
     6781 caataaatca ccaaaattcg gtcattggcg ggatacccat ttacgtgtaa ttgggcaatc
     6841 accaattcta atggaggtcc ggtttgcaat ggactggaac acgtcaatca gaagaacaaa
     6901 tttacctaaa tttgaattaa aggaacttaa accatttact gtcaatcgaa aagatatcaa
     6961 tgataataaa aatgtcgcta tgcaattgtt tcctcaggac ctgataatca acattacggc
     7021 atcagacgag gctgagggaa ttattgcagg agctaaaaaa tacatttata ttcaaacgcc
     7081 ttatttaatt cccgaagaat caattcttga agccttaatt atcgctgcta acagcggtat
     7141 tgatgttcga attatggttc cttgcatgcc cgatcatcca tttgtttatc gtgctacaga
     7201 atactatgct aagtatttag tagcccatgg cgttaaagta tacaaatata atgatggttt
     7261 tattcatgca aaaactatgg ttagcggttc taatatttct tcagttggtt ccgccaatca
     7321 agatttccga agctatacat taaactttga ggtaaactca ttcaactaca accctgcttt
     7381 aactcaagaa ttaaagaaaa tttttgagaa ggacttaggt aaatgtaccc ttttaactaa
     7441 tgactacttt gctcaacaat catcatggtt aaaatttaag caatacttct caagattatt
     7501 atcacctatt ttttaatgaa aagccctcta tcggtttatc cgatagggat tttactttgt
     7561 attttaaaaa tgcagtttta tttctttact tattttttat aggttatata atgataacta
     7621 ttaaaaagta aggaggataa aacttggcta atagagtaaa aataggcgtt ttgaatttaa
     7681 tgcacgataa gttagatact caacaaagat ttgcacgcgt tttgccagat gcagacctga
     7741 ctttctttta tccacgtatg cattatcaaa atcgtcctgt cccacctgaa gttgcaaaaa
     7801 cttcccagcc attagatctt aatcaaatca aagagtttga tggctttatc attacgggcg
     7861 cacctttaga tcatcttgat tttgatcaag ttacctacat cgaggaagtc cgatgtttgc
     7921 tccaactatt agataaatac aagttgcagc aattatattt ttgctggggt gcaatggccg
     7981 ctttagatta tttttacaat attcaaaaaa gaattttatc gaaaaaaatc tttggtgttt
     8041 ttcctcattt aattatcgaa ccacatcctt tattaaatgg actcagcaaa ggatttatcg
     8101 ctccacatgc tcgttacgct gaaatggata aaacacagat tatgcaagat ccacgattaa
     8161 ccattaattc agttgacgat aatgggcatc tatttatggt ctcttcttta gaaaagcctg
     8221 agcaaaattt tattttctct catatcgaat atggccgaaa aggccttaaa aaagaatatg
     8281 aaagagagat tgctgcacat ccagagcgac attataagaa gccagaaaat tattcattat
     8341 caaatctatt gtttcaatgg aaagatactc agaaaacatt tttcaataac tggctaactc
     8401 aagttaaaaa aagcaaatta gtattattag ataaataaaa cgaggcatac attatgtcta
     8461 caatttataa ttcagttaca gaacttatcg gcaacactcc attacttaag ttgaatcgcg
     8521 ttgtacctaa cgacgcggca gatgtctatg taaagttaga atttgaaaac ccagctggtt
     8581 caattaaaga cagaattgct ttagctatga tcgaaaaagc tgaacgtgaa ggcaacctaa
     8641 agccaggtgg cacaattgta gaacctactt caggcaatac cggtatcggt ttagccatgg
     8701 ttgctgcagc taaggactat cacattatta ttgttatgcc agaaactatg agcgttgagc
     8761 gtcgtaaatt aatgaagggc tatggtgctg aacttatttt gacaccaggt gcagacggta
     8821 tgaagggttc aattgctaag gccgaaaaat tagttaaaga aaaaggctac ttcatgccaa
     8881 tgcaatttga aaatacagaa aatcctaata ttcatgaatt aactactggt ccagaaatta
     8941 ttgccgcaat gaatggtatc ggcaaatccg ttgatgcctt tgttgctggt gttggtactg
     9001 gtggtacttt atcaggaatt ggacatgcac ttaggcgtga aaatccatcc actaagatat
     9061 ttgcacttga gccaactgaa tctccactct taaaagatgg aaaaacaggt aaacatggta
     9121 tccaaggtat tgccgcaggt ttcatcccta agaatttaga taaggatatc tacgatgata
     9181 taattacagt ttctactgat gaagcaatgg ctacagctcg tgaagtagct aaaaacgaag
     9241 gcttcttacc tggtatttca gctggtgcaa acatccatgg tgcaatcgaa attgctaaaa
     9301 agttaggcaa gggacatgct gtggttactg tagttccaga cggcggtgat cgttaccttt
     9361 caactgcatt gtttaatgct taaaacttaa tttctgtaaa caaatactcc taagtaaaat
     9421 ttccttagga gtattatttt tatttctgtt gattgtgcac cagtcaatgt tggtacaaca
     9481 cttttagtat aatgaccttt actaattaga tcaatattga atttatttaa gcaccatgat
     9541 attgcactaa gctgtaaata tcaacatcag gcaacttttc tctacccttt aaatcaggca
     9601 attcaatgta aaatgcagca cctacaagct taccaccaag attttcaatt aattccttag
     9661 aagctcttaa agtacctgca gtagccatta aatcgtcaca gagaacaact ctttggccag
     9721 gcttaattgc atctttatgc atttcaaggc tatttgaacc gtattccaag tcatatgaag
     9781 cacgttcaac ttctcttggc aacttatgtg gctttcttgc tggaacaaaa cctaagccta
     9841 actcagttgc aacaggacag cctacaataa agccacgtgc ttcaggacct acgattacat
     9901 ctgcctttct actctttgca tattctgcca attcatgagt agcaatacga tacaattcac
     9961 catcttgcaa aataggtgta atatcgcgaa agacaattcc cttattagga aagtccttaa
    10021 cacttgcaat atatttacta aaatcaatcg ccataagaag aaaaacctcc ataattctgt
    10081 gcgtttgtat tcaaacactt ttgacttgta tattttacca aagatttgtt ataaaagtac
    10141 tgaaatcttg atatttatct atctttttac caaattatta acatatgtaa ttaatttttg
    10201 agtaggcatc gttcttagtt gattaataaa tttaatttgt gaactcgttg ccattaaata
    10261 tttagaagct gtcaatggtt gcttctttgg attagactca ccaactaatt tttgatcgtc
    10321 taatttaaca aaacctaatt caaagaatac tcgcaaaata aacaatacac tatcataatc
    10381 caaacctaga tatggtgcta cagtgcgata gtcttcaggc tttaatgctg gatgggcata
    10441 aatatacttt aacacttttc cgaaataact ctttgctgga atttgttcaa caggtaactg
    10501 atctaataaa aagcataaat aaatttgttg ataatctttt tttaaagctg catttaattc
    10561 cacttgattg cgaggcacat caagcaaagc tactgtttca cccgattgat cataatcttt
    10621 aaccaagcta attttatcat catcaatttg aaggctattc ttaacaattg gaatattctt
    10681 tttgtcaaaa agcaaataac gatctgcaag gcccatgaca aatttctctt gtcttaaatc
    10741 aattactgat gttggcacag ctaattttgg ggatgcaaag gctattcctt ccatgatgcc
    10801 ttgcaaagat acttgtttgc gataagtatt caaagagaga gtaacaaaga tttttgaaat
    10861 aaacggtaac aaattattat tcaaataatc cttattaaat cccacaattg ctaaattgcc
    10921 gtctttttta ttagctgtta atttaacatg attcttatct tttcctattt tgaaaaagtg
    10981 tgtaatagtt ggatccgaaa tactaaaaat tggctgcgga tcaccagtac caaatggtcc
    11041 cacttgatta atttgagcca aagtttgagg tgataagtca tgcataggca attccatatc
    11101 gtactcttta gtctctaaac caccgtcaac atgaaaatcg gcttcaaact ttttccgtag
    11161 gtcatttact ttgtcttctt ccatggataa accacaagca aaatcatgac ctccaaattt
    11221 ggtcaataga ctttctttta acggattaag agcatcaaat aagttaaaac cactgaatga
    11281 acgacctgat cccttaatct ccccttcatc gtttttagtt aaaacaattg ttggtttatg
    11341 cagtttttcc actatcttgt tagcaacaag ccccaaaact ccttcatgaa aatcaggatc
    11401 atataaaact aaagtatttt gcttttgcca actattttca cgaactaatt ccatgcagcg
    11461 atcgtaaacc tcagtagtta gctctttacg cttattattt aagtcttcaa tctgatctgc
    11521 gatcttctgt gcctcaagat catcatcact aagcaaaagc tctactgcca gattagcatt
    11581 agccaaacgt ccaacagcat taagtctagg agcaatatta aagcctacat ctgtctcatt
    11641 aatcgtttct agcgttaaac cggcattttt gataagcgct cttaagcccg gtcgttcggt
    11701 ttgattaaga acatctaacc cacgttttac aataatatgg ccttcaccag taactttaac
    11761 catgtcacca atagtaccga tcattgctaa atctagcaat tctggtacag gatcctgcat
    11821 aagctcacga caaatcgtat aagctacacc tgcaccacaa taatcatcaa aaggatattc
    11881 ttgaccagga taattacagt gaacaattgc ataagcatct ggcttatttt cttgaaaagt
    11941 atggtgatcc gtaataatag tatcaacgcc atgttcttta gcgtattcaa ctt
//
