LOCUS       c00035_gnlPro..        16456 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FOIGHKFB_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 07:21:06
            Original ID  :: gnl|Prokka|FOIGHKFB_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16456
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16456
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7126:8169]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7127..8169
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
     cand_cluster    1..16456
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /kind="single"
                     /product="gallic_acid_met"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16456
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="gallic_acid_met"
                     /region_number="1"
                     /rules="(minimum(1, [Flavoprotein, Semialdhyde_dh]) and
                     gallic_acid)"
                     /tool="gutsmash"
     CDS             complement(3..290)
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MSSLNNCIKFALDIKDKNIVFKSFFYKMVQMKKHKIYEAELLQPA
                     CPCCGSLDLLHNGHLITNIHYLTANASHPVIIRLAKQRVKCRACNRWSMAQ"
     CDS             504..1088
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MNICSNEEVTNMLTRSHRLCSIALVELGVIASNAFIADPASNLII
                     LLATGVGASLPDIDEYNSTTSRKSLINFSLFLRHRGVTHSFLGWLVFSIGLYFIMNHFI
                     PIQFRSWQLPNWWGSIWLGLILGYFLHLVEDSFSKRGVDWWAPFVKKRRHHSIFRYKVG
                     GFFEKFITLIAFLGIIMMSCYWLWLLAAPEI"
     CDS             1200..1439
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="MNQIAFNQQLSDKLNEVLNPTLYSTPGKGEITVVANEKNDLREYR
                     IITENNKVVKVEDAYDAKHDADYDKMMDFLKDYR"
     CDS             complement(1441..2616)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_4"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-31, bitscore:
                     99.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGKLTTLATGATASNVAVMPIGKLPGFAQGFDTIPMWVADMDFPT
                     AKSIQEEIIKRDNQSPLFGYFQPSDAYYQAIIDWHKKRKGVSGLTKEDIGYENGVLGGV
                     VSALKVFAAPGDKVLLHSPTYMGFTNAVLSNGYQIVHSPLIKDENGTWRMDYEDMDNKI
                     KENQIHVAIFCNPHNPTGRVWTKEEITKAMEVYERNNVWVISDEIWSDLMMNDHHYIPT
                     QSVSEWAKQHTAAFYAPSKTFNIAGLIGSYSVIYNKPIRERIQSVGEKTVYNSMNVFSE
                     HALIGAYSDEGDNWLDQLLPVLSKNVNIAYDYVTKHFDGVSTFKTEGTFLDCTDWLKKH
                     GKTQKELLQRGWDYGIGWQDGGLFQGPTSNGKRKEQNQNRFCSFLYLYSNF"
     CDS             2733..3719
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="LKYYGTPKYKPFDPGSYYFGELQYNLDNGETLSSDYVKQISGKNW
                     ITAINNGHLYNAKGKRLSTKIKRGQTLAYSGKIKSTKNGKYYFYENNKKKRIPYYKIKG
                     RKYYKLGRNRYVKVADVIAVNGNCLMTTGETTGVVKNNNVRTFINSSDYSNDSTMAPSD
                     KYLKKGQKLTFDQAVTFVSQLDDFDHNPYDYYRIHLFVSADNLNLSKALPVHEFEDLYS
                     SRVELKAKTPIYNAMGEKTDQLLPLNHEVAVVEETSMADLNHVDEEVYLWVPSENKAEL
                     FYHVIGYPNSNTNELKDYGYIKTSEVKKFRGLKLEPINTAAEAKAYI"
     CDS             3676..4410
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="LSQLILQQKLRLTYKSALEKAIASAKETKRTTKYKLTDYDLKVRF
                     NSYLANAEKINTNNQATVLVVKQAQRELTNAEKALNGKKLKVGRYDQLTMTEVQKVLRL
                     GYNLVKTEHKGYVLPNIYNSKNNWQYVTDRPVWNFGKDSHFWLGYAAVDVKKKQPLNIK
                     ELAEESTKKPALKKLVKEYYGLKGNQYFIYNRQGKLVKKLKLKKEKVFKIRGHRIVKDQ
                     YMYQIGKNQYTPSLSFRWVIKK"
     CDS             4793..6172
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Branch_AA_trans"
                     /gene_functions="transport (smcogs)
                     SMCOG1000:Branched-chain amino acid transport protein
                     (Score: 432.9; E-value: 4.2e-132)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_7"
                     /sec_met_domain="Branch_AA_trans (E-value: 1.5e-132,
                     bitscore: 432.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDEKSRKLTWKQYLVVASLLFGLFFGAGNLIFPLHLGQLAGANW
                     GSAAVGFLITGVLLPLLSVLAVAITRAGGVYDIGKPLGAGFAVVFMVLIHATIGPLFGT
                     PRTATVSFTVGVAPFIPKDMQTVSLLVFSAVFFLLAFAFAYHENNILSNVGKVLNPLFL
                     ALLFLVFVVAFLNPLGNSQTAAVTAAYKHSALVNGFLEGYNTMDALAGLAFGVTVVTAV
                     RSMGQKDPKSVSKVVAKSGVVAMGTVALIYLLLILMGAMSLGHFKVSDNGGVAFNQIVN
                     QYGGLFGQALLAFLLTVTCLTTAVGLVAAFAQDFHKHFPKVSYHAWLALSCLASFLAAN
                     FGLDQIIAWSIPMLMFLYPLSMVLILLSVFSPLFKRDGVVYFFVILFTVVPALGDMVVA
                     FPAVVSQSQFGLMVAAVRSSLPLASMGLSWLVPALVGLVVGLAFHVFRRKNLVAAQEEF
                     E"
     CDS             complement(6233..6964)
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MPIGVIVNASSVLLDGMFGVFFGNKLSEDFKEKLNMIFGACSMGM
                     GIFSIAPMKYMPAVIFAVILGTIVGLVIHLGKWFNKGALLMQRPITKMIPTENLGISKD
                     EFMSLMVTATVLFCASGTGIYGALDEGMSGDITILVSKSILDFFTAAIFAASLGYAVSI
                     IAIPQFIIFVILFFLARFILPYTNSTMILDFKACGGFLMLATGFRIVKLKMFPIAEMIP
                     AMILVMPLSWLWGNVILNFIH"
     CDS             7127..7294
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: gallic_acid"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_9"
                     /sec_met_domain="gallic_acid (E-value: 3.8e-26, bitscore:
                     82.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQSVIGPSEEHVSMAGIPTEASILELVDKAIPGKVVNVYNPPAGG
                     GKFDDHHANP"
     CDS             7272..7652
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: gallic_acid"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_10"
                     /sec_met_domain="gallic_acid (E-value: 4e-37, bitscore:
                     118.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIMQIHKDNPADEGIQRQAAILAFSAFKELKTVWLVDEDVDIFD
                     MNDVVWTMNTRFQADQDFVCIPGMRNHPLDPSERPQYDPKSIRVKGMSSKTIIDGTVPF
                     DMKDQFIRAKFKEIPDWKKYLK"
     CDS             7666..8169
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_11"
                     /sec_met_domain="Flavoprotein (E-value: 2.9e-24, bitscore:
                     76.2, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKKIVIGISGASGSIYGIDLLKKLKQYKDVETHLVMNKWAMENIK
                     LETPYDPQNIIEMADFYYDNNNLGASISSGSFQVDAMVIAPASMKTVAGISIGFDADLI
                     MRAAGVMIKENKQLILVPRETPLYAIHLENLTKLAKLGVQIIPLYHLFMISQKLFKILS
                     TISQ"
     CDS             8227..8964
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ROK"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_12"
                     /sec_met_domain="ROK (E-value: 1.3e-10, bitscore: 31.7,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAKTFKVAKEDYEISADVLLENKDLLVSLTGGDIPHLGGVVTFD
                     FKSKKISKTFFESHDGRKHKDIFLAEQFAEKIKDHLMAIYYQAGELSFMIHDYQHAENM
                     AGNVGGSDSAVAFVKQVNALDNYDDKTDGLYAFNIINSGNLKALKLFHDYCWKIAVLIL
                     NIQSVVDVNKVAIGGGISAQPKLINGINQAYDELTKRKNPMIGATLVKPKIVKAHFQNG
                     ANLFGELDNLLLQINHENKYALN"
     CDS             complement(9304..10053)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     54.4; E-value: 3.1e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg35_13"
                     /sec_met_domain="HTH_1 (E-value: 1.1e-17, bitscore: 54.4,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIHEYKIFLDVCNTKNFSETARNDFITKSAIIQHINKLEQKLGI
                     KLFERTSRGVNLTDAGKALQPLAKGIIEKESEIIKTMHDYSHTLTIGTIYLEKPILINT
                     VLQKNNSKLRDFNINFQEVKNIKNVDNQIDIIEYYEITKYLDHSFNFLKLREEPIYIAM
                     PPSHPLSCKSSITLKDLSNYTVAIEKTGISAMGDKIGNILKRNPKINIKSFGVYNSSFF
                     ATALYHNYLMCIPKGMAQRPNHTLLNH"
     CDS             10204..10848
                     /locus_tag="ctg35_14"
                     /transl_table=11
                     /translation="MAIVNNDFHEILTGRHSVRRFDPSVKISRDEMKEMLEETITAPSA
                     CNLQAWKFVVVDTDEGREKLHKYFMKFNFPQVDKSSAVVLFFGNTLAYKKYSQLWHSMY
                     EAKKVTKEAMEAALNTFMPLYEKADQQMLAADSMVDTSLAAMQFMLIAREHGYDTNAMA
                     GYDATKAALTMGLDPKQYIPVMAIAIGKHDPNAEDEITTSRYPLSELVDFE"
     CDS             10868..11758
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_15"
                     /sec_met_domain="adh_short (E-value: 7.4e-48, bitscore:
                     153.1, seeds: 44, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDFNGKVAFITGAAHGFGKAIATKAASLGMKLTLVDQDKEALSK
                     VADELSKSTEVLKIVADVTEEKNVDNAVDEAMKKYNEIDLLVNDAGVAVPGPIWKLPTR
                     DWEWILHADLMSQVYALKKVIPIMMKQENGGDILNVASAAGLLTAPGMPAYYATKFAVV
                     GMTEAVAYDLQAYKQDKIHMHVFTPAFVQTHLMHSEEYRPKKYTDKTDPYYQSKTFKMG
                     QEMAKKDLTTGLPIKGVADTIFKGLEENKFYILTHKGIAPLVVKRAKDAVEGKAPNLVD
                     LMKYPDKTHTDTSLD"
     CDS             complement(11834..12391)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Shikimate_DH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_16"
                     /sec_met_domain="Shikimate_DH (E-value: 4.2e-09, bitscore:
                     27.2, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-15, bitscore:
                     48.3, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHGVNLLKLHPYQKALVIGDGFMGELFVQTLKAMGVHQVDLAGIS
                     EEKLKLNHDHFGVTTFNTAQGDKIPNNAYDIVVEAVGNPVTQEEAIAATRRGAQVLMFG
                     VANPKSQFKINSYEIYQKQLTIQGSFINPYCFEDAIGLLEAHKVDVLPLISHELSLGEV
                     EQFTSGKLKDVSKAVVKVKDLK"
     CDS             13011..13142
                     /locus_tag="ctg35_17"
                     /transl_table=11
                     /translation="MKKIGKLGLGAAVVSLFALLVGKKLNDQVDKADAEDRGVSKID"
     CDS             13300..14022
                     /locus_tag="ctg35_18"
                     /transl_table=11
                     /translation="MEYHKINQDDLKVLSSYISDPARFITNPATHWDYDQFNTVRAMPD
                     LVIQPVTNEEVQKVVKYASDHNIPIVPRGNSTGWMGANLTVEGGISLDMIKMNKLLEYD
                     PTSLTMTVQAGMRLIDIEKFLADKPFSYMPAPVMHWASIGGNVDTDAGGLKAVKYGVTR
                     EHIRQLKVVLTDGKLYKFGAKAVKSSSGYSLKDLIIGSEGTLVVVTEVTMRLYPTPRKS
                     INALTQLWMMLLNQYQLF"
     CDS             14031..14207
                     /locus_tag="ctg35_19"
                     /transl_table=11
                     /translation="VVPTTVEFMGRKVINLWEKYYNQKFPVDEGNGFILLGFDAFTDGE
                     VQAELKQAVATTK"
     CDS             14316..14747
                     /locus_tag="ctg35_20"
                     /transl_table=11
                     /translation="MDEVDICVPINHIPDVLHRVDELEKETGMRIPNFGHAGDGNLHIY
                     LCSDNMSDAEYKEKSDKVITELYKTAKALDGNMSGEHGIGYARKDWFEWYYGEDYTNLL
                     RKIKKVFDPNSVLNPDKIFPLKDNAKLTNLTYVNELVMS"
     CDS             complement(14815..16296)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_21"
                     /sec_met_domain="Peptidase_M20 (E-value: 1.4e-32, bitscore:
                     103.6, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFYFLQSVQLNFTIGLINLIKGEKYMNLDYKKLAAAKKDDILRD
                     LDELISIDSSEDLDNTSAEYPVGPGPVKAMKKFLSFAKRDGFHIKNVDNYAGRVDYGDG
                     EKRLGIIGHMDVVPAGDGWNTDPFKMLIKDGKIIGRGSADDKGPALAAYYGMLLLKEAG
                     FTPKKKIDFIVGTNEETNWVGIDYYLKHEPTPDQVFSPDAEYPIINGEQGIYTLILNFK
                     DDAQTGSVKLEKFTAGIAENVTPQKAYATISGADLANIKEQFTKFLADNDLEGNFEING
                     DEAKIELTGQGAHASAPQVGRNAATFLGKFLNQFDFAGRDKNYLNFLANVEHEDFKGEK
                     LGVAHHDDLMGDLSSAPSIFEYQADGDAILKDNIRYPQGTDPDKMVKQVEEKFSDILTA
                     SFNSFEEPHYVPGHDPLVKTLLKVYEHQTGKPGHEVVIGGGTYGRLFKHGVAFGAQPED
                     APMVMHQANEYMKVDDLIDSIAIYAEAIYELTKEA"
     CDS             16354..16455
                     /locus_tag="ctg35_22"
                     /transl_table=11
                     /translation="MDSLHSTMNQHIKGKHLSFEERVIIQTRLKDGCS"
ORIGIN
        1 gattgagcca ttgaccagcg attgcaagcg cgacatttaa ctcgctgttt agctagtctg
       61 ataattacag gatgactagc attagctgtc aaatagtgaa tattagtaat caaatgacca
      121 ttatgcaaaa gatctaaaga gccacagcaa gggcaagcgg gttgaagcaa ttcggcttca
      181 tagattttat gcttcttcat ttgaaccatc ttgtagaaaa agctcttaaa aacaatattt
      241 ttatctttaa tatcaagcgc aaatttaata caattattta aagaggacat agtacacacc
      301 tttacttata aaatgtttag tggaatagat tttttattac agaggactat gtcctccttt
      361 tttattgcaa taaaaaacct gttaacagct tatcatattg ataagcaatc aacaggaaaa
      421 attatagaac cattattaat aaaatagtgt gttttttctt gcaaataaga atgctgtcat
      481 ctcttatttt tgtatgttac aatatgaata tatgttctaa cgaagaggtg actaacatgc
      541 tgacgcgctc gcatcgttta tgcagtattg cgcttgtcga attaggggta atcgctagca
      601 atgcatttat tgctgaccct gcatctaatt taataatcct attggctacc ggagtaggcg
      661 cgtctttacc tgatattgat gaatataaca gcacgactag tcgtaaatct ctgatcaatt
      721 ttagcttatt tttacgacat cgtggggtaa ctcattcgtt tttaggctgg ttagtttttt
      781 caattggctt atattttata atgaatcact ttattcctat ccaatttcgt tcttggcaat
      841 tgccgaattg gtggggcagt atttggctag gcctgatttt aggctatttc ttgcatctag
      901 ttgaagatag cttcagcaag cggggagtag attggtgggc cccatttgtt aaaaaaagaa
      961 gacatcactc tatatttcgg tacaaagtag gcggcttttt tgagaaattc attactctaa
     1021 ttgccttttt aggaattata atgatgtcgt gttattggct atggctactt gctgcacctg
     1081 agatataagt aaaacgtgta cgtttattta gtaaatatct ttactagata tggtgaatga
     1141 tactacttaa tgttatacta acgttgttgg aaatatttta agaaaagaga tatattaaaa
     1201 tgaatcaaat tgcttttaac caacaattat cagataaatt aaatgaagta cttaacccca
     1261 ccttgtattc aactccaggt aagggtgaaa ttactgttgt tgctaatgaa aagaatgact
     1321 tgcgtgaata ccgcatcatt actgaaaaca acaaggttgt taaagtcgag gatgcttacg
     1381 atgctaagca tgatgcagac tatgataaga tgatggattt ccttaaggac tatcgttaat
     1441 ttaaaaattt gaatataaat acaaaaaaga acagaatcga ttttgattct gttcttttct
     1501 tttaccattt gaagttggac cttggaatag gccgccatct tgccagccga tgccgtaatc
     1561 ccaaccacgt tgcaataatt ccttttgcgt tttgccatgt ttctttagcc aatctgtgca
     1621 atccaggaac gtaccttcgg tcttaaaggt tgatactcca tcaaaatgct tagttacgta
     1681 gtcgtaagct atgtttacgt ttttcgaaag aactggcaaa agttgatcaa gccagttgtc
     1741 gccttcgtcg ctgtaagcac cgattaaagc atgttctgaa aagacgttca tactattgta
     1801 aacagtcttt tcaccaacac tttggatgcg ttcacggata ggcttgttgt aaataacact
     1861 gtaactacca attaatcctg cgatgttaaa agttttagat ggagcataaa aagctgcagt
     1921 atgttgctta gcccattcgc taactgattg ggtaggaatg taatggtggt cgttcatcat
     1981 cagatcggac cagatttcat cagaaataac ccaaacgttg tttctctcat aaacttccat
     2041 tgccttggta atttcttctt tagtccaaac gcggccagtt gggttatgag gattacaaaa
     2101 gattgcaaca tgaatttgat tttccttaat cttattgtcc atgtcctcat agtccatgcg
     2161 ccaagtacca ttttcatctt taattaaagg tgagtggaca atttggtaac cattgcttaa
     2221 gacagcgtta gtaaaaccca tatatgttgg tgaatgaagc aaaactttat cgcctggtgc
     2281 tgcgaagact tttaaggcgg aaacaacacc accaagtaca ccgttttcgt agccaatatc
     2341 ttctttagtt aaacctgaca cgcccttgcg ctttttatgc caatcaatga ttgcttggta
     2401 gtaggcgtcg cttggttgga aataaccaaa taggggagat tggttatctc ttttaataat
     2461 ttcttcctga attgacttag ctgtagggaa atccatatcg gctacccaca tagggatcgt
     2521 atcaaagcct tgtgcaaaac caggtaattt tccgattggc ataactgcaa cattacttgc
     2581 ggttgcgcca gtggcaaggg tagttaattt gcccacaaat aatatcgttc aagcagcaag
     2641 acagacagct agcggcaaaa tcaaagtaac ttaaacttac gctagttatt ttgctaacgg
     2701 taagagacac ccggttaaaa aggggaaaag tcttgaagta ttatggtacg cctaaatata
     2761 agccatttga tccaggcagc tattattttg gtgagttgca atataattta gacaatggtg
     2821 aaaccctgtc ttctgactat gttaaacaaa tttctggtaa aaactggatt acagccatta
     2881 acaatggtca tttgtacaac gcaaaaggca aacgactatc tactaagatt aaacgtggtc
     2941 aaactttagc ttacagtggc aaaattaaat ccactaagaa cggcaaatac tacttttatg
     3001 aaaataataa gaaaaagcga atcccttatt acaagatcaa gggacgcaaa tattacaaac
     3061 tcggtcgcaa tcgctatgtg aaagtggctg atgtgattgc tgttaatggc aattgcttaa
     3121 tgactactgg agagacgaca ggcgtagtta aaaataataa tgtcagaacc ttcatcaatt
     3181 ctagtgacta cagtaatgac agtactatgg cacctagtga taagtattta aagaaggggc
     3241 aaaagctaac cttcgatcag gcagttactt ttgtgagtca attagacgat tttgatcata
     3301 atccttatga ctattaccgt atacatctct ttgtttctgc agataattta aacttgtcaa
     3361 aggcattgcc ggttcacgaa tttgaagatc tgtattctag tcgagttgaa ttaaaagcca
     3421 aaaccccaat ttacaatgca atgggtgaaa agactgatca acttttacca ttaaaccatg
     3481 aagtggctgt cgtagaagag acttctatgg ctgatttaaa tcacgttgac gaagaagtat
     3541 atttgtgggt tcctagtgaa aataaagcag aactcttcta tcacgtgatc ggttacccta
     3601 acagcaatac caatgagctg aaggattacg gttatattaa aaccagtgaa gtaaagaaat
     3661 ttagaggatt aaagcttgag ccaattaata ctgcagcaga agctaaggct tacatataaa
     3721 tcagcactag aaaaagcgat tgccagtgcc aaggaaacta agaggacaac taaatataag
     3781 ttgactgact atgatttgaa agtcagattt aactcttatt tagccaatgc agaaaagatt
     3841 aataccaaca atcaagcaac tgttttggta gttaaacaag ctcaaagaga attaactaat
     3901 gcggaaaaag cattaaacgg caagaaactt aaggttggcc gctatgatca attgaccatg
     3961 acagaagtac aaaaggtttt gcgtttgggt tataacttag ttaaaaccga acacaaggga
     4021 tatgttctgc ctaatatcta taacagcaag aataattggc aatatgtcac tgatcgtcct
     4081 gtttggaatt ttggcaagga tagtcatttt tggttaggat atgccgctgt ggatgtgaag
     4141 aagaagcagc cattaaatat caaggaactt gctgaagaga gtacaaaaaa gccggcttta
     4201 aagaagttgg tcaaagaata ttatggcctt aaaggtaatc aatactttat ctataatcgt
     4261 caaggtaaat tagtcaaaaa gttaaaactc aagaaagaaa aggtctttaa gattagaggc
     4321 caccggatag tgaaggacca atatatgtac cagatcggta agaaccaata tactccaagt
     4381 ttaagctttc gttgggtcat caaaaaataa tattaaaaaa gtgttgacaa cgatgataat
     4441 tcgattaaaa taattattta caatttaatc aatctgaaaa caaatagaaa gaagagtaat
     4501 ttaattcgaa tttacagcga gtctcgttag gtgtgaggag ataaaggtag aattaaatga
     4561 aaatcacttt cgagttctat ttcttaatgt tttagtaaga aatagtggga gcacccgtta
     4621 tagtgcctgc gtatcgccga agtttcttcg gccgcacgtg aaaggtattg ctagtaatag
     4681 caatataaat aaagggtggt accacgctag aagcgtccct caatcaaagc aattttggtt
     4741 gagggacttt ttttgtgatc agataattct taattctcag gaggacgagt gtatgaatga
     4801 tgaaaaatct cgtaagttga cctggaagca atatctagtc gttgcttctt tactatttgg
     4861 attattcttt ggggcaggta acctaatttt cccacttcat ttgggacaac ttgctggcgc
     4921 aaactggggg agcgccgcag ttggatttct gatcactggt gtgttattgc ctttactatc
     4981 agtacttgcc gttgccatca ctcgtgcagg tggtgtttat gacattggta agccgttagg
     5041 tgctggtttt gcagtagtat tcatggtgtt aatccatgcg actatcggtc ctttatttgg
     5101 tacaccaaga acagctacag tttcattcac agttggtgtg gcaccattta tccctaagga
     5161 catgcaaact gtctcactat tagtattctc agcagtattt ttcttattgg catttgcatt
     5221 tgcatatcat gaaaacaaca tcttatctaa cgttggtaaa gttttaaacc cattattttt
     5281 agcactttta ttcttagttt tcgttgttgc atttcttaat ccattaggaa attcacaaac
     5341 tgcagctgtt accgcagctt acaagcattc tgctttagta aatggtttcc ttgaagggta
     5401 caatactatg gatgctttag ctggtttagc ttttggtgtt actgttgtta ccgccgttcg
     5461 ttcaatgggt caaaaagatc caaagagtgt ttccaaggta gttgctaaat ctggtgtggt
     5521 tgcaatggga actgtagctc taatctactt gcttttgatc ttgatgggtg cgatgtcatt
     5581 aggccacttc aaagtatcag acaacggtgg tgttgcattt aaccaaatcg ttaatcaata
     5641 cggtggtctc tttggtcaag cattacttgc atttttgcta actgttactt gtttgactac
     5701 tgcagttggt ttagttgctg catttgctca agatttccat aagcattttc caaaggttag
     5761 ttaccacgca tggcttgcac ttagctgttt agcatcattc ttagctgcta actttggttt
     5821 ggatcaaatc atcgcttggt caattccaat gctcatgttc ttgtacccat tatcaatggt
     5881 cttgatcctt ttatcagtat tttcaccatt gtttaaacgt gatggcgtag tttacttctt
     5941 cgtaatcttg tttacagtag ttcctgcatt aggagacatg gttgtagcat ttccagcagt
     6001 tgttagccaa agccaatttg gtttaatggt tgctgcagta agaagttctt taccactagc
     6061 aagcatggga ctttcctggt tagtacctgc tttagttggt ttggtagtcg gtttagcatt
     6121 ccatgtcttt agacgaaaga acttggttgc tgcacaagaa gaatttgaat aaaaataaaa
     6181 acttatctat tcatctttgg gtctgagtag ataagttttt tcgtttatat atttaatgaa
     6241 taaaattcag aattacgttg ccccataacc aagataatgg catgaccaaa atcatggctg
     6301 gaatcatttc cgcaataggg aacatcttta acttgacgat tctaaagcca gtagctaaca
     6361 ttaagaatcc accacaagcc ttaaaatcta gaatcatcgt tgaattagtg taaggcaaaa
     6421 tgaatcttgc taagaaaaat agaattacaa agatgatgaa ttgaggaatt gcaataattg
     6481 aaactgcata acctaaacta gctgcaaaga tagcagcagt gaagaaatcc aaaatagatt
     6541 tagatactaa aattgtaata tcacctgaca taccttcatc caaagcacca taaataccgg
     6601 taccactagc acaaaacaga acagttgcag tgaccattaa actcataaat tcatctttgg
     6661 aaattcctag attttctgtg ggtatcattt tagtaatggg tctttgcatt aataaagcac
     6721 ctttgttgaa ccattttcct aaatgaatta ccaatccgac aatggttccc aaaataactg
     6781 caaaaatgac tgcaggcata tatttcatag gtgcaataga aaagattccc atccccatag
     6841 aacaagctcc gaaaatcata tttagttttt ctttgaaatc ttcggaaagt ttattaccga
     6901 aaaaaacacc aaacattcca tccagtaaca ctgatgaagc attaactatt actccaattg
     6961 gcatttaata aacctctttt cttttttgta tggtgtcagt atagtgctaa aaagaacttg
     7021 ctctcaattc taaattgagt tttaataagt ccaatatgga caagctaatc cagcggttaa
     7081 tgtcgttaag attacagcag taacgcatag aaaagataat ccaattgtgc aatctgtaat
     7141 tggccctagt gaagaacatg tatcaatggc aggaattcct acagaagctt caattttaga
     7201 attagtagat aaagccattc ctgggaaagt tgtaaatgtt tataatcctc cagcaggtgg
     7261 tggtaagttt gatgaccatc atgcaaatcc ataaagataa tcctgctgat gaaggtatcc
     7321 aacgacaagc agcaatttta gcttttagtg cctttaaaga actaaagacg gtttggctag
     7381 tagatgaaga tgtagatatt tttgatatga atgatgtggt ctggacaatg aatactcgct
     7441 tccaagcaga tcaagatttc gtatgcatcc ctggaatgcg aaaccatcca ttagatccaa
     7501 gtgaaagacc acaatatgat cctaaatcta tcagagttaa ggggatgagt tcaaagacca
     7561 ttatagatgg aactgttcca tttgatatga aggatcaatt tatcagagct aaattcaagg
     7621 aaattcctga ttggaagaaa tatttgaaat aagggttgat tagttttgaa aaaaatcgtt
     7681 attggcattt caggagcttc tggaagtatt tatggaattg atttactaaa gaagctaaaa
     7741 caatataaag atgttgaaac tcatttagta atgaacaaat gggcgatgga aaatatcaag
     7801 ctcgaaactc cctatgatcc tcaaaacata atagagatgg ctgattttta ctacgataat
     7861 aataacctgg gtgcttcaat ttctagtggc tcttttcaag ttgatgcaat ggtcattgca
     7921 cctgctagca tgaaaactgt agctgggatc agtattggtt ttgatgcaga tttgattatg
     7981 cgagcagcgg gggtaatgat caaagaaaat aaacaactta tcctagtccc tagagagaca
     8041 cctttatatg caattcatct tgaaaatttg accaaactag caaaattggg tgtacaaata
     8101 attcccctat accatctttt tatgataagc caaaaactat tcaagatatt atcgaccatc
     8161 agtcaatgaa gatccttgat tctttaggta ttcaaaataa tatcgaaaga agatgggaaa
     8221 actaatatgc ttgctaaaac ttttaaagtt gcaaaagaag actatgaaat tagtgcagat
     8281 gttctattgg aaaataaaga tttattagtc tccttgactg gaggggatat tcctcatctt
     8341 ggtggagtgg tgacatttga tttcaagtca aaaaagataa gtaaaacatt ttttgaaagt
     8401 catgatggaa gaaagcacaa ggatattttc ctagcagagc agtttgctga aaaaatcaaa
     8461 gatcatttaa tggcaattta ttatcaagct ggtgagttaa gttttatgat tcacgattat
     8521 caacatgcag agaatatggc aggtaatgtt ggtggcagtg attcagctgt agcttttgtt
     8581 aagcaagtga atgctcttga taattatgac gataagactg atggcttgta tgcttttaat
     8641 attattaatt ctggcaactt aaaagcactt aaattgtttc atgattattg ttggaaaata
     8701 gctgttttaa ttttgaatat acaaagtgta gttgatgtaa ataaagtagc aattggtggt
     8761 ggcattagcg cacagccaaa gttgattaac ggaattaatc aagcttatga tgaattaact
     8821 aaacgtaaaa atcctatgat aggtgcaacg ttggttaaac caaaaattgt aaaagcacat
     8881 tttcaaaatg gtgctaattt atttggagaa ttagataatt tgttgttgca aatcaatcat
     8941 gaaaataaat atgctttaaa ttaaaaagat ggcagtgagt aagcatgcta aatgtttttt
     9001 tgaatatcat cagtgatttc gatgttgatg tatgtagcct atattgttca gactaaatct
     9061 aaatgatatt gattatttat ttttcacctt taaacttttc tggatgagaa cttacagttt
     9121 gccttacttc ttcaagcgtc catccaactt tcactttgcc agattgatca taaggacgat
     9181 aggatttttt atcctgttgt ctttttttgg ctcttgaaag ttatagtgct gataaaaact
     9241 gctttattgt gttgcttgga ttttttcgat agtaaattcc atagtatgcc ttttgtttaa
     9301 tatttaatgg tttaacaatg tatggtttgg ccgctgggcc attcctttgg gaatgcacat
     9361 taagtaatta tggtatagag ctgttgcaaa gaatgatgaa ttatacacgc cgaaactttt
     9421 tatattgatt tttggattgc gtttaagaat attgccgatt ttatctccca tagctgatat
     9481 gccagttttt tcaatggcca cagtgtaatt gcttagatct ttaagtgtaa tgctggattt
     9541 gcatgacaat gggtgagaag gtggcattgc aatgtaaata ggttcttctc gtaattttag
     9601 aaaattaaag gaatgatcca aatacttggt gatttcatag tattcaatga tatcgatctg
     9661 gttatcaacg ttttttatat tttttacttc ttgaaaattg atattaaaat cccttaattt
     9721 tgaattattt ttttgaagca cggtgttaat taaaataggt ttttcaagat agattgtccc
     9781 aatggttagt gtatgtgagt aatcatgcat tgtttttatt atttctgatt ctttttcaat
     9841 tatcccttta gctagtggct gtaatgcttt accagcatcg gttagattta ctccacgtga
     9901 agttctttca aataatttga ttccaagttt ttgttctaac ttgttaatat gctgaattat
     9961 tgctgattta gtaataaagt cgtttctggc agtttcggaa aaatttttag tattgcatac
    10021 atctaagaaa atcttgtact catgaatatt cattagtttt tgtcctttag ttaagttaca
    10081 ttatgtagag ttaagcaaat acttaactct gggataaaat aatagatcac acttatgatt
    10141 taaatctatt atactagcaa gtgaaagcga taacaaatta gtgaatagaa aagagatcta
    10201 attatggcaa ttgtaaataa tgactttcac gaaattctaa ctggtagaca ttcagtacgc
    10261 agatttgatc caagcgtaaa gatcagtcgt gatgaaatga aagaaatgct ggaagaaaca
    10321 attacagctc catctgcatg taacttgcag gcttggaagt ttgtcgtagt tgatactgat
    10381 gaaggaagag aaaaattaca taagtacttt atgaagttca acttcccaca agtagataaa
    10441 agctcagccg tcgttctatt cttcggcaat actttagctt ataagaaata cagtcaatta
    10501 tggcacagca tgtatgaagc taagaaagta accaaagaag caatggaagc agctttgaat
    10561 acctttatgc cactttatga aaaagcagat cagcaaatgc ttgcagctga ctcaatggtt
    10621 gatacatcat tagcagcaat gcaatttatg ttaattgcac gtgaacacgg ttatgacaca
    10681 aatgcgatgg ctggctatga tgcaacaaaa gcagcattaa ctatggggct tgatccaaaa
    10741 caatatatcc ctgtaatggc tattgcaatt ggcaagcatg atcctaatgc cgaggatgaa
    10801 atcactacta gcagatatcc attatctgaa ttagtagatt ttgaataatc aataagaggc
    10861 aaccataatg aaagatttta acggaaaagt agcgtttatt acaggtgcag cccatggctt
    10921 tggaaaagct attgcaacaa aagcagctag tcttggaatg aaattaactt tggttgatca
    10981 agataaagaa gcattatcta aagttgctga cgagttaagt aaatcaacag aagtattaaa
    11041 gatagtagca gatgttactg aagagaaaaa cgttgataat gctgtagatg aagcaatgaa
    11101 gaaatataat gaaattgatc ttctagtaaa tgatgctggt gttgcagttc ctggtcctat
    11161 ctggaaatta ccaacgcgag attgggaatg gattctccat gctgatctta tgagccaagt
    11221 ttacgcatta aagaaagtaa ttcctattat gatgaagcag gaaaatggtg gagatattct
    11281 taatgttgct tctgctgccg gcttattaac tgctcctggt atgccggctt actatgcaac
    11341 caaatttgct gtcgtaggaa tgaccgaagc tgtagcatat gatttgcaag cttataaaca
    11401 agataagatt catatgcatg tatttacacc tgcttttgta caaactcatc taatgcattc
    11461 agaagaatac agacctaaga agtatactga taagactgat ccatattatc aaagtaaaac
    11521 ctttaagatg gggcaagaaa tggctaagaa agacttaact actggtttac ctattaaagg
    11581 tgttgcagac actatcttta aaggattaga agaaaacaaa ttctatatct taactcataa
    11641 aggtattgca ccattagtag ttaagcgcgc taaagatgca gttgaaggta aggcaccaaa
    11701 cttagttgat ttaatgaaat atccagataa gacgcataca gatacatctt tagactagag
    11761 tttgtttaaa tcttaaaaag tcttcaagtt attgtaaaaa tacggatagt tgccttttta
    11821 ctagttttag ctattatttc aaatctttaa cctttacaac cgcttttgaa acatccttta
    11881 atttaccaga agtgaattgt tcgacttcac ctaaagataa ttcatgagag attaatggta
    11941 aaacgtcaac tttgtgagct tcaagtaaac caatggcatc ttcaaagcaa tatggattaa
    12001 taaatgagcc ttgaatcgtt aattgctttt gatagatttc ataagaatta atcttaaatt
    12061 gtgacttagg gttggctaca ccaaacatta agacttgtgc accgcgacga gttgcggcaa
    12121 ttgcttcttc ttgggtaaca ggattaccaa cagcttctac tacaatgtca taagcattgt
    12181 taggaatctt gtctccttgt gcagtgttaa aagtagtgac gccaaaatga tcatgattga
    12241 gctttaattt ttcttcagaa ataccagcta aatcaacttg atgaacgccc attgccttta
    12301 aggtttgaac aaataattcg cccataaagc cgtcaccgat gactaatgct ttttgatagg
    12361 gatgcaattt taatagattt acaccgtgca tagcacaaga aagtggttcg gttactgcag
    12421 cggctttaag cgcaagatta tctgaaatag ggtagacact tttgcagggg ctgtgaagta
    12481 ttccgcaaaa ccgccatcac gggtaacgcc tacggcagaa aggttttcac aaagctctgg
    12541 acgagaggtg cgacagtagt aacattgacc acaataaata ttaggatcga ctgttactcg
    12601 gtctcctggt tttacattgg tgatattttt accaatggct ttgacaatgc cagagttttc
    12661 atggcctaaa ataataggtg gatttgcttg agcagaccct ggcaaaccat tatatagttc
    12721 acggtcagtg ccacaaatac ccgcataagc cgtatgaatt aaacctcatc atcttttgcc
    12781 tgtggggtag gaaattcttt ttcttctaat tttttagttg ctgttaaaac taatgcttgc
    12841 ataatttttc ctcgattctt tataaatagg ataacccatt tagaggtaaa tgtactttca
    12901 tagatgaaaa ttatgaatta tttaagcttg actaaataaa agcagaatat atgtttttgt
    12961 catttgaaaa ctaatataat agaagaaaaa tgaaatgagg tagcattata atgaaaaaaa
    13021 tcggtaaatt aggcttaggg gcggctgtag ttagtctttt tgctttatta gtcggaaaga
    13081 aattaaatga tcaagtagat aaagctgatg ccgaagatcg tggtgtcagt aaaatagatt
    13141 agtaaaaatc tggatggaag cgtaccattc agattttttt gtttgattgt tagaaaaata
    13201 aatgcatctc actttgtaag cgcagacagt aacaattata ataacgatag ttacttaatt
    13261 aaacataaca acagagtata tacaaaggag agaaaaataa tggagtatca taagatcaat
    13321 caagatgatt taaaagtttt aagttcttat atttctgatc ctgcacgttt tattactaat
    13381 ccagcaactc actgggacta tgatcaattc aatactgttc gtgctatgcc agatttggtc
    13441 attcaaccag ttactaatga agaagtacaa aaagttgtta aatatgctag tgatcataat
    13501 attccaattg ttccaagagg caattcaact ggctggatgg gtgctaactt aacagttgaa
    13561 ggtggcatct cactagatat gattaaaatg aataagctgc ttgaatacga tccaacttct
    13621 ttaacgatga ctgtacaagc agggatgcgg ctaattgata ttgaaaaatt cttagctgat
    13681 aagccattct catatatgcc agcaccagtt atgcactggg cttcaattgg tgggaacgtt
    13741 gatacagacg ccggcggatt aaaagctgtt aaatatggcg ttactcgtga acatattcgt
    13801 caattaaagg tagttttaac tgatggtaaa ttatataagt ttggtgcaaa agctgttaag
    13861 tcctcatctg gttactcact caaagatttg attattggct cagaaggtac attagtcgtt
    13921 gttactgaag taacaatgcg gctttaccca acaccaagaa agtcaattaa tgctttgacc
    13981 caactctgga tgatgctatt aaatcagtac cagctatttt agattcaggc gtggtaccaa
    14041 ctaccgtaga gtttatgggt agaaaagtaa ttaatctctg ggagaagtac tataatcaaa
    14101 aattcccagt tgatgaagga aatggcttca ttttgcttgg ctttgatgct tttaccgatg
    14161 gtgaagtaca agcagaattg aaacaagctg ttgctacaac gaagtaattc aagtcagcaa
    14221 cgccaatcgt acttgacgct gactcagaag aagctaaaac tatttggaaa tgtcgtgaag
    14281 atttactttt agctattcaa aaattaactc ctaagatgga tgaagttgat atttgtgtac
    14341 caatcaatca tattccagat gttttgcata gagttgatga gcttgaaaag gaaactggaa
    14401 tgagaattcc taactttggt cacgctggcg acggtaattt acacatttac ctttgctcag
    14461 acaatatgag tgatgcagaa tacaaggaaa agagtgacaa agtgattact gaactctaca
    14521 agactgctaa ggcacttgat ggtaatatgt ctggtgaaca tggtattggc tatgctagaa
    14581 aagattggtt cgaatggtac tatggtgaag attacactaa cttattaaga aagattaaga
    14641 aggtctttga tcctaactcc gttttgaatc cagataagat tttcccatta aaagataatg
    14701 ctaagttgac aaatctaact tatgtaaacg aattagtaat gagttagaaa aataatctaa
    14761 aaggacaaaa aaagatgatc attttcctgt ttggaaaaag atcatctttt tattttaggc
    14821 ttcttttgtt aattcgtaga ttgcttctgc ataaatagcg attgaatcaa tcaagtcgtc
    14881 caccttcata tattcgttag cttggtgcat aaccattggt gcatcttcgg gttgagcacc
    14941 gaaggctaca ccatgcttga ataatcgacc ataagtaccg ccaccgataa ctacttcatg
    15001 acctggcttg ccagtttgat gttcataaac tttaagcaaa gtcttaacta atggatcatg
    15061 gcctggaacg tagtgaggtt cttcgaatga attaaatgag gcagttaaga tatcactgaa
    15121 tttttcttcc acttgcttaa ccatcttatc tggatcagtg ccttgtgggt aacggatatt
    15181 gtcctttaaa atagcatcac catcagcttg atattcaaag atacttggag cacttgaaag
    15241 atcacccatt aagtcatcat ggtgggcaac gccaagcttt tcacccttaa agtcttcatg
    15301 ttcaacatta gctaaaaagt taaggtagtt tttgtcacga ccagcaaaat caaattgatt
    15361 gagaaactta cctaagaagg tggcagcgtt gcgaccaact tgaggagcag aggcgtgagc
    15421 accttgacct gtaagctcga ttttagcttc atcaccatta atttcgaagt ttccttctaa
    15481 gtcgttatca gctaaaaact tagtgaattg ttctttaatg tttgccaaat cagcgccgct
    15541 aatagtagcg taggcttttt gtggagtgac gttttcagca ataccagctg taaacttctc
    15601 aagtttaact gatccagttt gggcatcgtc tttaaagtta aggattaaag tgtaaatacc
    15661 ttgctcaccg ttaatgattg ggtattctgc atcaggagag aatacttggt ctggagtagg
    15721 ttcgtgcttt aagtagtagt caataccaac ccagttggtt tcttcattag taccaacgat
    15781 gaagtcgatc ttctttttag gagtaaagcc agcttctttt aataaaagca taccgtagta
    15841 tgcagcaaga gcaggacctt tatcatctgc agaaccacga ccgataatct ttccatcctt
    15901 aatcaacatc ttgaatgggt cagtattcca accatcacct gcaggaacta catccatgtg
    15961 accaatgatg ccaagacgtt tttcaccatc accatagtcg acgcggccag catagttgtc
    16021 aacgttctta atgtgaaagc catctctttt agcaaatgat aaaaatttct tcatagcctt
    16081 aactgggcca ggaccaacag gatattctgc agaagtgttg tctaaatctt cagaagaatc
    16141 aatcgaaatc aattcatcta aatcacgcaa aatatcatct tttttagcag cagctagttt
    16201 cttgtagtct aaattcatat atttctctcc cttaattaaa ttgattaggc cgattgtaaa
    16261 attaagttga acactttgta aaaaataaaa gtccatctgg acctgtttga tagaatgtta
    16321 ataaccacaa aaaacatcta ttggaggtca caaatggact ctttacattc taccatgaat
    16381 cagcacatta aaggcaagca cttgtcattt gaagaacggg ttattatcca aactcgctta
    16441 aaagatggct gctcta
//
