LOCUS       gnlProkkaLHAADEOA_105   3661 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LHAADEOA_105.
ACCESSION   gnlProkkaLHAADEOA_105
VERSION     gnlProkkaLHAADEOA_105
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 06:10:03
            Original ID  :: gnl|Prokka|LHAADEOA_105
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3661
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3661
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[283:3148]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      284..3148
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3661
                     /SMILES="NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3661
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(284..3148)
                     /NRPS_PKS="Domain: AMP-binding (8-390). E-value: 1.3e-68.
                     Score: 223.4. Matches aSDomain:
                     nrpspksdomains_ctg105_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (501-540). E-value: 1.1e-07.
                     Score: 24.2. Matches aSDomain:
                     nrpspksdomains_ctg105_1_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     184.7; E-value: 3.9e-56)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-69, bitscore:
                     220.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.9e-09, bitscore:
                     24.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.3e-09, bitscore:
                     24.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIIDNFIQRSQNTPDQVAVKSPNGDYTYQEISNIAQQLAAKLDE
                     ENAQDIVPFYLKDTRFVLPTVIGIWLSNRIPMPLVSALDLPEATDRVKEVQWDTLITDL
                     PATLKQKNIIQVDLFNQNNHADFKAKPFSQKNVYILSTSGSTGIPKKVFLTESNLKWIL
                     TRLYSLINVNETTKFLFSTPYSFDVSLTELLSPVIAGAELVCLPTSPSNSESIRLIPKL
                     INQKQITHLSLSPSFAEALLDIVGPEAFDKLKFLMVAGEAFPINLAKKLKRALNKGCKV
                     FNLYGPTETTVYSTYHQVTENEEEYVPIGRPLPEGKVKVLDANNNEAKKGELYIGGNGV
                     TDGYLLDSVKSSSSFITLDGERYYKTGDKVEILQNGELLFLEREDDQVQVNGIRVELGE
                     IQTLVSKIADVTTAIAKFKNKRIYIFYISSQDKEAEIKSKLPTYLNPIIIKVDHFLYTY
                     NRKIDTQRMIDEYYNRSLTTDSSNTLDELKKLIAKYHVNEIKELDSLDSVRFIVDVENT
                     FKIQIDDAQFSLLNTLERLAAYIDKQQTNTAAETREQANEADLLNLKLLFANFSSSYED
                     AKITASSTQQSLFSQQKPSFDLLRVSFPTINFEEIQKIRQIFTDLTTKIDLLKFAWFKD
                     RDGKLYFKKIINPAPISLVTANSFSETDLEKVMYSKPGSPIHCLIFNMKKQELNIVFSH
                     HALDASSSNKLKKIFVDLYQGNLKIEQIKSSSYAEFMSFVQEVNQSTDLKAALSLVPQT
                     QEELNLTKEDGRLYITKFACPAKTTDQIYINGLYLLSQAMMKDHKMKKITGKIALNIRK
                     FSNFDASDVIGDIHATLPWEVNENDTLTDFAKRYQMWKDHYTKGTDYRYCIFNQIGSNL
                     EYRNALSKQWSNMNISPNYIGEVNSVKAIADDILRLPFKPNYITMVSKEGVLYCISYGR
                     LLEKFKYQVKLNDEQVVTVTTNEY"
     aSDomain        complement(1529..1645)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg105_1_PP-binding.1"
                     /evalue="1.10E-07"
                     /label="ctg105_1_PP-binding.1"
                     /locus_tag="ctg105_1"
                     /protein_end="540"
                     /protein_start="501"
                     /score="24.2"
                     /tool="antismash"
                     /translation="LDSLDSVRFIVDVENTFKIQIDDAQFSLLNTLERLAAYI"
     aSModule        complement(1529..3124)
                     /complete
                     /domains="nrpspksdomains_ctg105_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg105_1_PP-binding.1"
                     /locus_tags="ctg105_1"
                     /monomer_pairings="Ala -> Ala"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1946..2011)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg105_1_0003"
                     /evalue="5.80E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg105_1"
                     /protein_end="401"
                     /protein_start="379"
                     /score="25.1"
                     /tool="antismash"
                     /translation="FLEREDDQVQVNGIRVELGEIQ"
     aSDomain        complement(1979..3124)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg105_1_AMP-binding.1"
                     /evalue="1.30E-68"
                     /label="ctg105_1_AMP-binding.1"
                     /locus_tag="ctg105_1"
                     /protein_end="390"
                     /protein_start="8"
                     /score="223.4"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="QRSQNTPDQVAVKSPNGDYTYQEISNIAQQLAAKLDEENAQDIVP
                     FYLKDTRFVLPTVIGIWLSNRIPMPLVSALDLPEATDRVKEVQWDTLITDLPATLKQKN
                     IIQVDLFNQNNHADFKAKPFSQKNVYILSTSGSTGIPKKVFLTESNLKWILTRLYSLIN
                     VNETTKFLFSTPYSFDVSLTELLSPVIAGAELVCLPTSPSNSESIRLIPKLINQKQITH
                     LSLSPSFAEALLDIVGPEAFDKLKFLMVAGEAFPINLAKKLKRALNKGCKVFNLYGPTE
                     TTVYSTYHQVTENEEEYVPIGRPLPEGKVKVLDANNNEAKKGELYIGGNGVTDGYLLDS
                     VKSSSSFITLDGERYYKTGDKVEILQNGELLFLEREDDQVQV"
     CDS_motif       complement(2084..2158)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg105_1_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg105_1"
                     /protein_end="355"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="GELYIGGNGVTDGYLLDSVKSSSSF"
     CDS_motif       complement(2684..2737)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg105_1_0001"
                     /evalue="3.80E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg105_1"
                     /protein_end="155"
                     /protein_start="137"
                     /score="13.5"
                     /tool="antismash"
                     /translation="YILSTSGSTGIPKKVFLT"
     CDS             3565..3660
                     /locus_tag="ctg105_2"
                     /transl_table=11
                     /translation="MNDFTKNIAQALFNQDKINDLLRKELQQAVND"
ORIGIN
        1 gtgttacata taattattaa taaatttagt tttctaactt aattagcttc attcgtacca
       61 ataattctaa taaaataatc tattaaatta ttgatattac ttgacttaag gtagaaaaag
      121 aaccgaatca aaatgattcg gttcatcaag tcagatcatc aatcaatgtc ttaacttaat
      181 gacattggac tccgatagaa tatcgaaatc aagctttaaa agaatttatt taaaactaac
      241 gtccaacttt aggggttagc ttcatagctt agttggcttt tttctaatat tcatttgttg
      301 ttacagtaac tacttgctca tcattcaatt tcacctgata cttaaatttt tcgagtaagc
      361 gcccatatga aatgcaatat agcacacctt ctttcgaaac catagtgatg taattaggct
      421 tgaacggcag ccttaagata tcatccgcaa tcgcctttac tgaatttacc tctccaatat
      481 aattaggtga aatattcatg ttgctccact gtttacttaa agcgttgcga tattctaaat
      541 tactgccaat ctgattgaaa atgcagtagc gataatccgt gcccttagta tagtgatctt
      601 tccacatttg atatctcttg gcaaaatcag tcaaagtatc attttcattc acttcccaag
      661 gtagggtagc gtgaatatct ccaattacat cgctagcatc aaagttcgaa aacttcctga
      721 tattcaaagc gatctttccc gtaatcttct tcatcttatg atctttcatc atcgcttgtg
      781 acagtaagta aagaccgtta atgtaaattt gatccgtcgt tttagcaggg caggcgaatt
      841 ttgtgatata gagtcgacca tcttctttag ttaaattgag ttcttcctgc gtttgaggta
      901 ccaaagaaag ggccgccttt aaatcagtac tttgattaac ttcttgaaca aaactcataa
      961 attcagcata agaactggac ttaatttgct caattttcaa atttccttga tacaaatcta
     1021 cgaatatttt cttcaatttg ttagaagaag aggcatctag agcgtggtgt gaaaagacaa
     1081 tgtttaactc ctgcttcttc atattgaaaa taaggcaatg aattggcgaa ccaggcttag
     1141 aatacatcac tttttctaag tcagtttcgg aaaagctgtt tgcggtaaca agtgagattg
     1201 gagctggatt gattatcttc ttgaaatata gtttaccgtc tcgatcttta aaccaagcaa
     1261 atttcaatag atctatctta gtagttaaat cagtaaaaat ctgtctaatc ttctgaattt
     1321 cttcaaagtt aattgtcgga aaagatactc ttagcaggtc aaaagatggt ttttgttgtg
     1381 aaaagagact ctgctgcgtt gatgaagcag taattttcgc atcctcatag ctgctcgaaa
     1441 agtttgcaaa cagcaattta agattaagta agtcagcttc atttgcttgc tcgcgagtct
     1501 ctgcagctgt atttgtttgc tgcttgtcaa tatatgctgc caagcgctca agcgtgttca
     1561 acagtgagaa ctgggcatca tcaatctgaa tcttaaaagt attttctaca tcaacaatga
     1621 agcgcactga atccagagaa tccagctctt taatttcatt aacgtggtat ttggctatca
     1681 actttttcaa ttcgtctaaa gtgttagagc tatcagtagt caaagaacga ttataatact
     1741 cgtcgatcat tctttgcgta tcaatcttac ggttgtaggt gtacaagaag tgatcgacct
     1801 taataattat tggattgaga taagttggca gtttactttt aatctcagct tctttatctt
     1861 gcgaactaat gtaaaaaata tagattcgct tgtttttgaa cttcgcaatt gctgtggtaa
     1921 catcagcgat tttcgatact agagtttgaa tttcacctaa ttccacacgg attccgttaa
     1981 cttggacttg atcgtcttct ctttctaaga aaagtagctc accgttttgt aaaatttcta
     2041 ccttatcacc agttttataa tagcgttcac cgtcaagagt gatgaagctt gagctgcttt
     2101 taacagaatc taaaagatag ccgtctgtta ctccatttcc gccaatatat aattcacctt
     2161 tttttgcttc attattgttt gcatcaagga cttttacctt tccctctggt aatgggcggc
     2221 caatcggtac gtattcttct tcattttcag ttacctgatg ataagtagaa tagacagttg
     2281 tttcagtcgg accataaaga ttaaaaactt tgcatccctt attaagcgcc cgtttcaatt
     2341 tttttgccaa attaatcgga aatgcttcac cggctaccat cagaaacttg agtttatcaa
     2401 aggcttcagg accaacgata tcaagaagtg cctccgcaaa tgaaggggat aaggaaaggt
     2461 gcgttatttg cttttgatta attaatttgg gaattagcct gatactctct gaattagaag
     2521 gacttgttgg gagacaaacc agctcggcac cggcaataac gggcgacaga agctctgtta
     2581 atgaaacatc aaaagaataa ggcgttgaaa ataaaaattt ggtcgtctcg ttgacgttaa
     2641 ttaatgagta cagtcttgta aggatccact ttagattgct ttctgtcaga aaaacttttt
     2701 taggaatgcc ggtactgcca gaagtagaga ggatgtatac atttttttgc gagaacggtt
     2761 tagctttaaa gtcggcgtga ttattctgat tgaaaagatc aacttgaatg atatttttct
     2821 gcttaagtgt ggcaggtaag tcagttatta aagtatccca ttgaacttct tttacacgat
     2881 cagtggcttc aggtaggtct aacgctgata caagtggcat agggatgcgg ttggatagcc
     2941 aaattccaat tactgtgggc agtacaaaac gggtatcttt taaataaaag ggaacgatgt
     3001 cctgagcatt ttcctcatca agtttagcgg ctaattgctg ggcaatattg gaaatttctt
     3061 gataggtata atcaccattt ggtgatttaa ctgccacttg atcaggagta ttctggctgc
     3121 gttgaataaa attatcaata ataaacatac tgaaactcac ctttctgttt tatatttagt
     3181 tccttttcta tgaaatacta gatagagagg acctacatta gaaattaaat atgctatgct
     3241 actttcaaac gctagaagga aattatttac cggtaatttt ccgtgtaaat ttttcgcgat
     3301 tgaattagat aaccagaatc gaagaaatgt ggtagttaga taaactaaag taaaaactag
     3361 tgctaatcca ctatttataa aaataagaaa tataaagata actagataaa agctaggtag
     3421 taatagccat gcaagagact gtaaaatagt ttgtgtaagg atgaatgatt ccttaaatta
     3481 atttcttaaa acattagaaa aaggagttcc tttctcgtat gattggtttg aacaaaaaac
     3541 acatacagaa agaagaactc cttcatgaat gattttacca aaaatattgc tcaagctcta
     3601 ttcaatcaag acaaaattaa tgatttattg cgtaaagaat tacaacaagc agttaatgac
     3661 t
//
