LOCUS       gnlProkkaBPNKCPDM_1    21612 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BPNKCPDM_1.
ACCESSION   gnlProkkaBPNKCPDM_1
VERSION     gnlProkkaBPNKCPDM_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 06:12:17
            Original ID  :: gnl|Prokka|BPNKCPDM_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3928890
            Orig. end    :: 3950502
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="10"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(207..3869)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 76.9; E-value: 1.7e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5237"
                     /transl_table=11
                     /translation="MFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQYDKVVRST
                     HGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFSWYIYSPLR
                     VKYPYVRGVLINLWREALQTHQNPLEAWKSIVENPEKAKSYKQARGKGGFVRAEWPEVL
                     KLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFYDWYADLPP
                     ASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAKVISISPDF
                     AESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTDFPFLVTLS
                     KENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDGQQKWNLHM
                     IDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNGEETYITTV
                     FDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREFAQNAIDTD
                     GRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLRPAEGWQTI
                     ATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHADYNVLAARL
                     GWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGAYVASQLQEKKLKFAIEDPDNEVNFPR
                     NLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAPEGKLDLLI
                     NLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESKSDWDIFKA
                     LSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAIPGKTMPNI
                     QVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITSDSVAKGCP
                     NISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECFTFEQITAQ
                     PKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMMEFGETMATF
                     KPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGGPTVWMNKD
                     DAEDTDIKDNNWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPGTKLTNNRG
                     GTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDWLED"
     CDS             complement(4088..4564)
                     /locus_tag="ctg1_5238"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     CDS             4708..5427
                     /locus_tag="ctg1_5239"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPTCCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     CDS             complement(5459..5794)
                     /locus_tag="ctg1_5240"
                     /transl_table=11
                     /translation="MSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYGVERSDGILI
                     NIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLRCEIECENCP
                     LEICNID"
     CDS             complement(5833..6174)
                     /locus_tag="ctg1_5241"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKISWKKN"
     CDS             complement(6273..6977)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 60.7; E-value: 1.7e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_5242"
                     /transl_table=11
                     /translation="MQMYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWF
                     LSLFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKM
                     SPLRILMFVFAGLTLSGIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQA
                     GIANGIVSAMGGLGGFFPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERM
                     KTHTERNSQSIN"
     CDS             7119..7349
                     /locus_tag="ctg1_5243"
                     /transl_table=11
                     /translation="MENTAPPIPKKKPPAIKSNRESAILIQNTGNKSRMKLTINMSRAP
                     NLFVKYPKGMRRSDPRITGIAVTKEISPLLK"
     CDS             complement(7530..9263)
                     /locus_tag="ctg1_5244"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKCNHDQKDKVFGLCPFFMRKRV
                     M"
     CDS             complement(9260..9688)
                     /locus_tag="ctg1_5245"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             10001..10132
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_5246"
                     /sec_met_domain="Subtilosin_A (E-value: 1.2e-28, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg1_5246_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="ctg1_5246_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     CDS             10281..11612
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_5247"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1069.0, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 6.9e-29,
                     bitscore: 98.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.5e-07, bitscore: 28.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.5e-21, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.1e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.2e-09, bitscore: 36.1,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASRHTITT
                     SGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDNGVLTC
                     EITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVGISLDS
                     VNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKVRDLGA
                     KAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQHVIDEFKDLIPIIPYERKRAANCG
                     AGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRFSEHCM
                     KDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             11625..11786
                     /locus_tag="ctg1_5248"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             11783..12502
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 127.7; E-value:
                     9.5e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_5249"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             12495..13805
                     /locus_tag="ctg1_5250"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNTYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCISAALMPAATIPLCAVHILWAVVIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRSIS
                     VLTFLQCIELLLAGAYIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLAILAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             13771..14010
                     /locus_tag="ctg1_5251"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDAFGYAAGSRFMYSANLFLISS"
     CDS             14028..14954
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5252"
                     /sec_met_domain="Peptidase_M16_C (E-value: 4e-05, bitscore:
                     22.1, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHPLYNGNLHVDALMKTFADLSFPSSLSFEAFEKARNELLLKIE
                     KKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHPKRFLDATDFIVDLVSQQKQ
                     LNILGQVQACDVRGHAPQTSAVTSGRIPVNRHVFETETRSAAGPSVLTLGFDCGEMKDA
                     SDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYDVMNNLLLVSICTDQLHEID
                     IPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGLLAYMGILRRFSCTKEALLD
                     GISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             14959..16239
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5253"
                     /sec_met_domain="Peptidase_M16 (E-value: 3.5e-13, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKSFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCLRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDIGDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLAIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHISQKEAIRQ"
     CDS             16236..16688
                     /locus_tag="ctg1_5254"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAFAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPLPFQ"
     CDS             complement(16941..18317)
                     /locus_tag="ctg1_5255"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDLAEVS
                     AAVTWSTDNVSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSAVPTNLGVTFDKAFTYILHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIVM
                     "
     CDS             complement(18357..19712)
                     /locus_tag="ctg1_5256"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEIGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAVYVIGIDTLTVDRSIPVEG
                     YDVAIDPNGLFAYVLNFGIVQKVDLTTGEVTGTIERELIVSTIETNWPERYAYVLEQEF
                     FFNYLTVIDLNTFTISSTQELEYEGEYRMFTSGAEVYLYDGFTGNLYSVSPNGAGVIGN
                     VPQSARDFAFTPNGEFLYATHVLEQSITVYNTDDYSVETVISLGVSPGAIAI"
     CDS             19942..20742
                     /locus_tag="ctg1_5257"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYF"
     CDS             20772..21086
                     /locus_tag="ctg1_5258"
                     /transl_table=11
                     /translation="MDKAHEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQG
                     FFDFLESKMLYADLEDFAIDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV
                     "
     CDS             21070..21189
                     /locus_tag="ctg1_5259"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
ORIGIN
        1 gctttccttt tttcaatgtc cagccgcctt tatatttgtc ctggtcctcc cattgcttcg
       61 ggtagccgat gcccggcttt gtttctacat tattgaagta catatattcc gcaccggaac
      121 ggtttgtcca cgtgtttttg caagtgacgc tgcacgtgtg gcagccgatg catttatcca
      181 agttcatgac cataccgatt tgcgctttaa tcttcaagcc aatcgacctc cttcagcttg
      241 cggatgacga cattcaggtc gcgctgattc cccgttgggc cgtaatagtt aaagccgtag
      301 ctgagctggg cgtagccccc gatcatctgt gtcggcttga cgtgaatcct tgtcgggctg
      361 ttatgggtgc ctccgcggtt atttgtcagt ttcgtgccgg gcacgttgat gtggcggtcc
      421 tgggcatggt gcataaacgc cattccttta ggaatccgat gagacaaaac ggctctcgcg
      481 acgactacgc catttcggtt gaagcattca atccaattgt tgtctttgat atccgtatcc
      541 tctgcatcat ctttattcat ccatacggtc ggcccgccgc ggaacagcgt cagcatcggc
      601 agggaatcaa aatacatgct gtggacggac catttgttat gcggcgtcaa ataattaagg
      661 acgatttctt ttccctcttg atcaggccgc ttgcttagaa acgggcggtg ctggaggatc
      721 ggtttaaatg tcgccatcgt ttcaccgaat tccatcatca gttcatgatc gacataatag
      781 gattgtctgc ctgtcagcgt ccgccacgga attaattttt caacattcgt tgtaaacggc
      841 gaatacctgc gccctccttt ttcagagccg gtaaacgctg gagacgtgat caccgttttc
      901 ggctgggctg taatttgttc gaacgtaaag cattcttcct cgcgttcttc cgccaggtct
      961 ttcagcttca ggttcgtgat gttttcaagt gattcccatg cttttactgc gacctttcca
     1021 ttcgaagtgg atgatagggt taaaatcgct tctgcagcct gctttgcttc acttatattt
     1081 ggacatccct ttgccacgct gtccgaggtg atttctccca gtctctgttt gagtgattca
     1141 tattcatcgg ctattgacca gctcatccct tttgttccgc tcggctttaa agcaacgttc
     1201 ggaccaagtg cagtcatttt atgaaaaatg tgtttgtaat cccgttcaac gacttggatg
     1261 ttcggcatcg tttttcccgg aatggcttca cattcgcctt tgctccagtc attgattttg
     1321 ccgaatggct gggccaattc ctgcatggtg tcgtggagca gcggtgtcgc aaccacttct
     1381 ttcaccggct ccatatcgac ttcttctgcc agatcggaaa cggcttttga cagcgccttg
     1441 aaaatatccc agtctgactt cgattcccac ggagccgaga tcgcaggagc aaatggatga
     1501 atgaacggat gcatatctgt gctgctgaga tcgtgttttt cataccatgt cgccgccggc
     1561 agcacgatat cggaatacag cgccgtaccc gccattcgaa aatcaagatt gattaataag
     1621 tcgagctttc cttccggcgc ctgctcccgc catttgattt cttctgggcg gatgctgtcg
     1681 ctgtcgtcat tcattaaacc gttcgttgtc cccagcaaat gcttgagaaa atattcatgc
     1741 ccttttcctg agcttgagat cagatttgcc cgccatacaa agagattcct tgggaaattc
     1801 acttcattgt caggatcttc aatcgcgaat ttcagttttt tctcttggag ctgtgaggcc
     1861 acgtacgcac ctacgtcttc aggtgttgct gcccctgctt tttcagcttc tttatacaga
     1921 tcgatgccat tttgattgaa agtcgggtaa gacggaagcc accctagccg cgccgccagc
     1981 acattgtaat cagcgtggtg cttgtagcgg gatgaagcag caatcggtga tgccaaatca
     2041 ctgatcggct ggtcctcata acgccactga tctgtcgcaa agtagaaaaa tgaggtgcca
     2101 ttttgcagct tgggcacgcc ttcccagtcc tttgcagttg caatcgtctg ccacccttca
     2161 gcaggtcgga gcttttcctg ccccacgtaa tgggcccagc ctccgccgtt tacgccttgg
     2221 gcgcctacaa gtaaaacaag atttaacact gctcggtaga tcgtgtcgga gttgaaccag
     2281 tggttaatgc cggcccctac gataatcatg gaccggccgt ctgtatcgat cgcattttgg
     2341 gcaaactctc tggcaatctt aacgacagct tcttttttga ttcctgtcat ttgttcctgc
     2401 caggcaggcg taaacggctc agggtcatca taggagacag ccgatcgttc gccgatgccc
     2461 cggttcacgc cgtagttagc cagtatcaag tcaaacacgg tcgtgatgta cgtttcttca
     2521 ccgttcaggt tcattttttt aataggaaga tcccgctcga gcactttgtt tccgtcattt
     2581 gaaaaatacg ggatgcgcac cgtgccgatt tcgtcctcta ttcccagcac agagagacgg
     2641 ggttcaatcg gttccccggt ttcttcatca atcatgtgca ggttccattt ctgctgcccg
     2701 tcccagcgcg agcccattgt cccttggggt atggcaaatg aacttgtctg ttcatcccaa
     2761 accgcaggct tccactgatc atgctttgtc ttccgcccga tgtccttcgc atgcagaaac
     2821 cgtcccgctg tgtatacgcc attttctttt gacagagtga cgagaaatgg aaaatcagtg
     2881 tattgcttcg cgtactcaat aaaacgttca gtttcttggt tcacgtaaaa ttcctgcaga
     2941 ataacgtgac ccatcgccat cgcaagcgcc ccgtcagtcc cttggcgaat actcagccag
     3001 tcatccgcga actttgagga ttccgcaaaa tctggactga tcgaaatgac cttagcgcct
     3061 ttatagcggg cctccgccaa aaaatgcgcg tcaggcgttc tcgttaacgg aacgttggag
     3121 ccccatgtga taatatagcc ggaattgtac caatcactgc tttccggaac gtccgtctgg
     3181 tcaccccaaa tttgcgggga tgctggagga agatccgcat accagtcata aaaactgagc
     3241 atagggcctc cgattaacga cataaaccgg gagcctgatg cgtggctgat catggacatg
     3301 gccggaatcg gagaaaaacc gacgtttcgg tcaggcccgt atttcatcac tgtatacagc
     3361 agagaggctg aaatcagctt cagcacctcc ggccattcag cgcgcacaaa accgcctttc
     3421 cctctcgcct gtttatagga cttcgctttt tcagggtttt cgacgatcga tttccaggct
     3481 tccaatggat tttgatgcgt ctgcaatgcc tcccgccaca aattgatcag cacaccgcgc
     3541 acgtatggat atttcacacg gagcgggctg tagatatacc atgaaaaact ggccccccgc
     3601 gggcagcctc tcggttcaaa atcaggcata tccgggcctg ttgatggata attcaaattt
     3661 tgcccttccc acgtgactat tccgtttttc acataaatat tccagctgca agaccctgta
     3721 cagttgacgc cgtgggtgga gcgaacgact ttgtcgtact gccatctgtt tctgtataca
     3781 ttctcccaat cgcgatcctc gcgggtagtt tggctatgtt tatttgaatg gtgttcgata
     3841 ggagagaaat aattcaatct cctaaacaac ggactccttt tcttttcttc atgagagttc
     3901 actccttccg agtcaggtga tgctaagttc actataaaca gagacagcgt gtttccttgt
     3961 gaactatgtc acacactctg cttttttcac aaaatgttca cacaaaggag aaggaaggct
     4021 gcgttcaggc aggacgcttg ggtcattagc tgcctttcat tcaaagatca aaaaaaaccg
     4081 gctctattta agaaccgggc tcagcgtttt catcctgtga tgtatgcaga taccgcaaaa
     4141 ataattgata ggaacaaaaa acattttgct gaagcatagc caaaaagttc atttgcagct
     4201 gcggatgata agacatcatt ttcttaaata tgtaatatgg gatgttgaga atcagaatgt
     4261 ctgaagtggc attgactgag ataaagggcg ataaataaag cccgcctttt tcatcaatcg
     4321 gaaacacatc gcctttttcc cacagcgcaa cggttttcga cccttcaggg agccttgtgt
     4381 ccataaaacg gacactgcct tttaatacaa tataaacaga ttgagaatga agaaaagatg
     4441 gagactgatc acatgaaccg cggataaacg tgccgttttt cagcaaggtt tcgacaatgg
     4501 atagaggcac ttcattaaac ataggaagtt gtttcagaaa taataaatag tcacactgat
     4561 tcataggaaa acctcctgtg ctaaggatag ctttagtgta gctcgactga gcctgtacag
     4621 cagtgatgta tttcacagcc tgtatgatga atgtcactta tcaggagggt gaatgcattt
     4681 ataatgaaag aaaaaaggag gatttcgatg aaggcgctga ttccgaagca gcacggggcg
     4741 tgggcgatgc tgctgatccc atttttactc ggcatggtca agggaggccc cgttatttgg
     4801 catattccgc tcttccttgg ttggcttttc ctatacttag cggtttatcc cgttacgctt
     4861 gccttaaaaa agaaacaaag caaaccatat caaaagtgga tgtgttatta cggttttccc
     4921 acctgctgct ttttgatgat ctcggtcttt cataagccgc ctctcatctg ggtgggcgtt
     4981 tctttactgc cgctgtttct catacatatg tattttgccc gcagaaaaaa cgaacgagcc
     5041 ttattgaatg atgttgcagg tgtcttgttc ttttgttcgg gcgggtttgc gagctgctgg
     5101 ctggggatgg gaacccttga cggctgggct tggtttattt tcttgcagtc tgctttattt
     5161 tttatcggga gttcctttta tgtgaaatcg gtgatccgcg agagaaaaaa cagggcattt
     5221 gcatactggt catggggata tcacctgctg ctcccctttt tatccgctct tttcggagca
     5281 ggatgggcgt ttctcgcttt tatcccgagc agcttgcggg catggttttt tcatggaagg
     5341 gattggcccg taaaaacgat tggcattctg gaaatcgtga atgcctgctt ctttcttgcc
     5401 gtcatgtgcc tgtttatcac aaggtaaaaa aacaaggaca ccgctgtcct tgtttttttc
     5461 agtcaatatt gcaaatctcc agcgggcaat tttcacactc aatctcacat cgtaaatagt
     5521 cccgcttgtg caaaataatt tttccggatt cgtctatcga aataacccct tttttgcgga
     5581 gatctccgag catacgattg acgctttccc gtgcagccgc gcaaaacttt gccaaatcct
     5641 gatttgtcag gacaatgtta atcagaatgc cgtcgcttcg ctccactccg tagctgtttg
     5701 ataaacggat aagggtggaa tagagcgccc cctttttgcc atgaagaagc agatccctga
     5761 ttttggactg aatcttccgg aggtgcgtgc tcatccattt catgaactca aatgtcaaag
     5821 cgccgttttg gattaattct ttttccagct tattttatta atgacgagca cctcgccatc
     5881 ctctagcact tttgcactga gcatatacct cggttcttca gtgaaaagtg ttaattctcc
     5941 gacgatatca tgcttttggc agattctaag cgtcaggtct tttccgtcag atgtcagctt
     6001 gccgatttca atgagtcctg attgaatcag ataaagctct tctgcatcca ttccttctcg
     6061 aaacaaatac gtgtgttttt ccatttttct tttcgtgctg atcgattcca gcagttcatg
     6121 cagatcgctg gatataagat cactatcaga tggtcgaaca gagagaaaat tcatgagctc
     6181 acctcgaaga aagtcacgtt gtgtgtttat tgtaacgtga attgatttgt acccatcgag
     6241 aaaaaactaa caatcttgtg aatgccccag tgttagttga tgctctggct gtttctctcc
     6301 gtgtgtgttt tcattctttc ctgccaatac atccatatga caaggacaaa gctggctaac
     6361 gccacctctg aaagcgccat aaacccgatc gcgtactggc ctgttgcctg aaatacactc
     6421 gccaatatga gcggaggaaa aaagccgcct aatccgccca tggcagacac aatcccattg
     6481 gcaatccccg cttgcttcga aaaatagaaa ggcaccagtt taaaaacagt cccgtttcct
     6541 atgcctgagc agacggccac ggttaatgat ccaaacgtat aaaggccgat tgtcggcgag
     6601 aacgatagga taatgcctga taatgtaagc ccggcaaaaa caaacatcaa gatgcggagc
     6661 gggctcattt tatcagccag gaatccgcct gcaggcctga gcagcgtaga aaccgcaata
     6721 aagccagccg tccgcaagcc ggcatctgca ggattcagcc caaaatgctc caccagaaag
     6781 ttcggcagat agatagtgaa ggcgacaaag gcaccgaacg taataaaata aaacaggctc
     6841 agaaaccata gcacatgatt ccggtaaacg gctttgattt gagtcttaac agaaactttg
     6901 accttcttct catgcctgtc accgaacaaa acgtgcagta aggcaaagac agccagcaaa
     6961 accagataca tctgcacggt tgatttccac ccgacggctt gagcgataac cggcgctgca
     7021 aatgtcgtaa cggctgtccc gatatttcct gcaccgtaaa tcccattgac gacaccgtgc
     7081 tttctttcgg ataatatttc gggagggagg tcaccccaat ggaaaacacc gctcccccga
     7141 tccctaagaa aaagccgcct gcgattaaat caaacagaga atccgcgata ctgatccaaa
     7201 atacaggaaa taaaagcagg atgaagctaa ccataaacat gagccgcgcg ccaaacctgt
     7261 tcgttaaata ccctaaagga atgcggagaa gcgacccgag gatcacagga atcgccgtca
     7321 ccaaagaaat ctcacccttg cttaaatgaa tatctaatgt gatttgggaa atgagtgatg
     7381 aaatcagcac ccaaaccata aaccctgcca ccaagcttaa tgactgtaac gataattgaa
     7441 tgtgttgacg gttgatcatt tggcttgccc ctttcaatga ttcaataatc agtcttatca
     7501 tacaaaaact agccaaacag gattgtgaat tacatcacac gttttctcat aaaaaaagga
     7561 caaagcccga agactttgtc cttttgatcg tgattacatt tttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggcttttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagttagtg acacggtgcg gaattcgttt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagcc cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgtgc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ctgcacttcg cattgcaaag
     8041 aagtaacgca cggcatccaa gccgacttct tcaatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatac cccagcgctt cgattgccgc tttcatacgc
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agcaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccgaac gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccttgtcgat ttttccattt
     8461 tggtacagtg aagtttctga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tttccagctc gtatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcctctt cgttaacgaa acgatcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct caccgcggta gccatcctcc ggcatcggtt tttccaatcc gagtgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg ttcgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gccttccctt tatcaaaatg ggcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccaactgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttga tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa aatatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt attcagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg tggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagcc tggagctttt gaagacttac aagcaaaaaa
    10921 tcatcgtcgg catttctcta gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgctatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcgt tttcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattgtccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaca tgtgattgat gagtttaaag atctgattcc gattattccc tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagtccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcaa gcgccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc ggaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttactt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gttttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 taggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtc ttttatcaga aaatgcgtga gtactgtgaa gcaggcggaa ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcta ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 cgaggtgatc ggccatgaat aacataatcc ctatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat cgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctt ttgatgaaca catatatggt gtttctttcc gtgacatcac
    12721 aatggaagga atcttatatg aagctgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtatcag cgccgctttg atgccggccg ccacgattcc gctttgcgcg gttcatatcc
    13081 tgtgggcggt ggtcattgac tttcctgtct ttctgcaggc gcctccgcag cagggcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggtattcagc ggcttctttt
    13261 cgttccagat gatgaacacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtattc gattgaaaaa aatgaccgga
    13381 tgctgctcat cacgcttccg atcaagcgaa aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgttcgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagcgt
    13561 atatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 tattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatttcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacgattt atttttacgg cgccgccgca
    13921 tacctgaagg agcaaatcat tgacgctttt ggttatgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tctttttgat cagcagctga aaacctgcgg gacccgtttg attcacccat
    14041 tatataacgg gaatcttcat gttgacgccc tgatgaaaac ttttgcagac ttgtctttcc
    14101 cttcttctct ttcattcgaa gcatttgaaa aggccaggaa tgagctgctg ctgaaaatcg
    14161 aaaagaaatt cactgatccc ttctcctact cggcggctcg cttggctgag gaggtcttcg
    14221 gaaacccgat gtacggcaca ggcatgtttg gccggaaaga caggataaag gcgattcatc
    14281 ctaaacggtt tctcgacgca acggacttta tcgttgattt agtgtcccag caaaaacagc
    14341 tgaacatatt gggacaagta caagcatgtg atgttcgggg acatgccccg caaacgtccg
    14401 ctgtaacgtc cggaagaata cccgtaaacc ggcatgtttt tgaaacagag acacgcagcg
    14461 ctgcaggtcc ttccgtcttg acactcggat ttgactgcgg agagatgaaa gatgccagcg
    14521 attatatcaa aatacagcta atagacggat tactgggaaa gtacggccat tccgctttat
    14581 tcaagcactt cagagagaag gatctggcag tctatcacgt tatcacccgt tacgatgtca
    14641 tgaacaattt gctgcttgtt tcaatatgta cagatcagct tcatgagata gacattcccc
    14701 cgcgcgtttt ggaagctgtc tcagcttttc atacagatga gcgggaacta gaacaggcaa
    14761 agcagttttt acgcaatgaa ttgctgctgc aattcgattc tcccgaaggt ctattggcct
    14821 atatggggat cctgcgtcgc ttctcctgca cgaaagaagc cttgctggat ggcatctcag
    14881 cggttacatg ccgcgatgta ttgcaattca tagcgaccat caattatatc ggagctcatg
    14941 tagtaagggg atgaagagat ggaaaagaaa tccttttttc aacagctgga tgaacgaacc
    15001 gatatcagat acacagacag cggactaaaa atattcagat tgaaattccc ccgcgcccac
    15061 ctgcggctgt gcaatgtaaa aatcgatttt ggaagccggg atgtatgttt acgggcagaa
    15121 tccggtgata cactgcttcc gtatggcaca gcgcattttt tagagcatct tctcttctgg
    15181 cataacggcc gcaatctgta cagtgatttt tttgcgcatg gcgcgctttt aaacgcattc
    15241 actacctaca ccgataccaa tttcatgttt acctcattac cggatcggct cagacaaacg
    15301 atccccatcc tgcttgatgc tttatggaac cactcatttg acaagaagat tgtcgctcag
    15361 gaaaaagctg tgattacaag cgaaattcaa acagcacacc ttaaccatca gctctcatat
    15421 cattatcagc tgatcagcat gctttctccc tcctcaccag ctgccgtttt ccccgcaggc
    15481 agaatcgagg atattgaggc gctggacatc ggtgatttac aaaaagccta taaggctgcc
    15541 taccaagccc atcggatgac gctgtttttg attgggggct cagaaaatac agaaacgctt
    15601 ttgcctcctc acctccagct ggaaaagcgt ccggattatc atgctgaaag aaaaatcatc
    15661 ccggcatgcc ctccagccct ctcacaaaaa atggtgctgg gtgatgagga gcggatggaa
    15721 gatacatgga ccggattaca gatcggcgca cttcccgggc aaaacgatct gttggcgata
    15781 aagctttatt gggatatcgc ggctcgtatt ctatttcaat tagattcacc gttttttcaa
    15841 gagattcagc aaacgtaccg cctagaaatc gatcgtttgt cagccgagac ttatatctat
    15901 gaggatggcg gtttcttgat ccttcacagt caagggaccc attcttcagc ttatatcgat
    15961 gtggcttcat actatgtcac acagaagaaa gaacaggttg ccgcctggct tcaatacggc
    16021 aaggactctt tgacagacgc gatcatttat gacagcgatt atgtgcgtaa atgcttcgag
    16081 tgggcagccg agtgtgacag gtgcgattgc tcgtttcttg acatgtacca catcattcaa
    16141 gatatggatg cgcaggtttt cttgtctctc attgatgcaa tggcatcttc taacaaagcg
    16201 atcattcaca tttctcagaa agaggcgatc agacaatgaa aaaaaacact gtctttaccc
    16261 ttttattgct gcttataggt atggcggctt attccttcgg ctgggttcag gcctttgccg
    16321 aagccgccgc ccaatatgta cagatgatca acaatgatgc tgtgcggctc ggactgctgg
    16381 cttgtaccgc tgccctcctg atgctgcctg cttttctcta tcttcattat gtcacccaat
    16441 ccgtgaaaaa catgacagca gcttttcaga aactcacaca gtctcatcaa agctgctgtg
    16501 actttcagca acacaacttg tgcagccgat atgcagaaga cgtcaaatcg ctgcgtgaca
    16561 gctataaaaa cgtccgccaa acatacgtga tggctgccgt gttgtgccaa gtcatcatat
    16621 tcggctgcat gttcgaaatc gttaaagccg tccctttccg ccttcacacg cccctgccct
    16681 ttcaatagga cttgcgatgc tactgatcct gtatttattg ttttgcatgc gaacgtattt
    16741 gcggcagctt ttccggcacg gcagcctgtt cagaaaagtg tttgcgggag tgctggcagc
    16801 agccgggatt tggtggatgc tcagtttctc tataagtgaa cttctgtttc tgattatcct
    16861 ggctgccatc caacaaatcg gatcatttat ttataaacga ttctcttatc gcagcaccgc
    16921 ttctcttgat ctataaatag ctacatcaca atcgcagacg gacccgcgcc aaccggaatc
    16981 accgtcacgg ctgtataatc acttgtgcgg tacacggtca cagcattgtc gttgggctgt
    17041 gccgcataaa tatactgttt gtccggcgtt acggcgaggt caaaagcgcc ggggagagac
    17101 acgtttgcaa tgatcctctg tctggccgta ttaactacat ataagttatt aatgagaaac
    17161 ggttcactat atggctctag aaaataagct ctagtgctat cgagagaaaa tacaatcgtc
    17221 ctcagcgttt caaataaacg gctgaagtct cctcccctgc ttaatggtga caaactaatc
    17281 tccgttacac ctttcggcca cagctcacca ttcaacacgt acgcaaaatt tccagcgtaa
    17341 ggagttgcaa ttaaactggg aaattcaaat gtatctatga tactttctac caactgccca
    17401 gtatttacat catatttatc aaccgaccaa ctgcttccat tagcggtata gacatactgt
    17461 ccattcggat caagagcaaa gtctaaagcg ccgggtatcg gaatgacatc aattaccgat
    17521 tgagaggccg tgttaatcac atatatagat ccggcggcca tcacgtatgc gaactcatct
    17581 gttggatcaa attcgatctt tctcggccct cctccaacag taatggtatt tatgatcgtt
    17641 aatgttttat tatcaatcac tgagacaagg ttggtatttc catggaggat atacgtgaat
    17701 gctttatcga aagtaacgcc tagattagtt gggacagcag aaaacgggat tgtttttaca
    17761 acagtgttta aatctgcatc aataaccgaa accgtgctgt ctccagtatt ggcagtaaac
    17821 acatacgatt gagggtctgg tgatggcggt aaaacaagtg tcccggtcac cgtaagcgga
    17881 ctgccgtaga aaggcggtac aatgagcaga tcttccactg ttatttgact gaaatcagga
    17941 cagcggccag actgtgctgc ataataaaca acttgatcaa tctcttcagt atgaatcaca
    18001 gaaaccgccc cattgccttg tccatattga tttcgcacag gcgacacact gacaagaagc
    18061 gtaatggtcc cttgtactct cacagcatat cgaacaccga tatcttctgg ttccggccca
    18121 gtctggatta agcaaggctc actgatacag gacacattgt ctgtactcca tgtaacagcc
    18181 gctgacactt cggccaaatc aaccttgaag ccctcaggga tatctatcgg cacttgaaac
    18241 ggcgcttccc ggctaatttc ctcatcacaa aaacagaaac aattttcctg taaagcagaa
    18301 agatcattct ttttcatgat ttcacgtcct tttagaaatg cacaacatat agttgattaa
    18361 atcgcaatag ctcccggtga aaccccaaga gatatgacag tctccacgga gtaatcatcc
    18421 gtgttgtaaa cagtgatgct ctgttctaga acatgagttg catacagaaa ctcgccattc
    18481 ggggtaaacg caaagtctct tgccgactgc ggaacatttc ctataacgcc tgctccattt
    18541 ggactgacag aatataaatt gccagtgaag ccgtcatata aatacacctc tgctccactc
    18601 gtaaacattc gatattcccc ttcatactcc agctcttggg tgctgctgat ggtaaacgta
    18661 tttaaatcaa taaccgtcaa ataattaaaa aagaattctt gttctaatac ataggcatac
    18721 cgctccggcc aatttgtttc tatggttgat acgataagct ctcgttcaat tgttcctgtg
    18781 acttcaccgg tagttaggtc cactttttgc actattccaa aattcagaac ataggcgaat
    18841 aacccattgg gatcgattgc aacatcatat ccttccacag gaatcgacct atccacagtt
    18901 aacgtatcaa ttccaatcac ataaaccgca gtaccggtga aaacataagc aaactcatga
    18961 ttagggataa atctaatcaa tcgaggcggc tgatccagca atatagttgc tgtcactgtt
    19021 aatgtgtcat aatcgatgac agaaatcaca ttattgttgg gatgtaagac aaacacagcg
    19081 cttttatctg gcgtaatttc aatacctgcc ggattgtacg gaagagcaat cgttgtcaca
    19141 acagtatggg tgtttgtatc aatcacagaa actgattgat catttggatt cgctgtaaac
    19201 gcgtagacgg gttccggctc cggtacaagc acaatcgtcc ccgtcaccga taaaggactg
    19261 ccgtaaaacg gcggaacaac aacaaggttc tcaatcgtga tgtcactgat atccgggcaa
    19321 tcatccggtt catcggaata atagacgact tgatcgattt ctgcattgtg aatgacggaa
    19381 acagccccgt ccccttgtcc atattgattt cgcacaggtg agacactgac gagtagcgta
    19441 acggttccct gcaggcgcac tgcaaattga acaccgatct catcaggctc aggccccgtt
    19501 tgaattaagc aacggtcact gacacaagaa aggctgtctg cattccacgt cacgtttgca
    19561 acagcttcag ccggatcaac gacaaatcct tcaggtaatt caatcggcgc ttgaaacatg
    19621 gcttctcggc ttgcttctcc ctcacaaaaa cataagcact cttcttgttc tgctcctgct
    19681 ttttctttaa aggaaagctt attttttctc attccttcac ttccttttca gacatacact
    19741 gctcacgcag atataacaga atatggaagt gtaacgtgtt tgcttgtaca aattgctgag
    19801 ggtaaacgct tctttttgaa aatatatctc caaacatgcg gtgtaacgaa agaaaaaatt
    19861 gcggtttttt tgcgcttctc acaagaatgt tgatgataaa atatgacata tatagaatta
    19921 tgaagggagg gatttgcaaa cgtgacaggt gtcatatctt cttcttccat cggagaaaag
    19981 attaacgaat ggtatatgta catacgccga tttagcatac ccgatgcaga atatttgcga
    20041 cgagaaatca agcaagagct ggatcaaatg gaagaagatc aagaccttca tttgtactat
    20101 tcactgatgg agtttcggca caacctgatg cttgagtacc ttgaaccgtt agaaaaaatg
    20161 aggattgagg aacagccgag actgtctgat ctgctgcttg agattgataa aaaacaggct
    20221 cgtttaactg gtctgcttga gtactatttt aatttcttca gaggaatgta tgagctggat
    20281 cagcgggaat atctgtcggc tattaaattt ttcaaaaagg ccgaaagcaa gctgatattc
    20341 gttaaggatc ggatagagaa agctgagttt ttctttaaga tgtctgaatc ttattactat
    20401 atgaaacaaa cgtatttttc aatggactat gcacggcaag catatgaaat atacaaagaa
    20461 aatgaagctt ataatataag attgctgcag tgtcattctt tatttgccac caatttttta
    20521 gatttaaaac agtatgagga tgccgtctca cattttcaaa aagcttattc tatggcagaa
    20581 gctgaaaagc agccccaatt aatgggaaga actttgtaca atatcgggct ttgtaaaaac
    20641 agccaaagcc aatatgagga tgccataaca tatttcaaaa gagcaatagc tgtttttgaa
    20701 gaatcaaata ttcttccttc cttacctcaa gcgtattttt aattacacag atccattata
    20761 aattaggaaa aatggataaa gctcatgaat atcatagtaa gggaatggct tattcacaaa
    20821 aggccggaga tgtaatatat ttatcagagt ttgaattttt gaaatcttta tacttatcag
    20881 gcccggatga agaagcaatt caaggatttt ttgattttct cgaaagtaaa atgttgtatg
    20941 ctgatcttga agatttcgct attgatgtgg caaaatatta tcatgaacgt aaaaattttc
    21001 aaaaagcttc tgcttatttt ttgaaggtgg aacaagtaag gcaacttatt caaggaggag
    21061 tgagtttgta tgaaattgaa gtctaaacta ttactctctt gtctggctct aagcactgtg
    21121 ttcgtggcaa caactattgc aaatgcacct acacaccaaa ttgaagttgc acaacgagga
    21181 atgatttaat gaatacaacc ggttttcacc ggttgttttt ttgttaaata cacaatcggg
    21241 acaaaagttt tattttttaa tctctaaata ttattactaa ctaatttaaa ttggttacct
    21301 aacccacaaa cataggaaac aagataattt ttattatatg aaaataaaaa tatgtttact
    21361 tttccttttt tttgaactaa tatatatatg acttaagttc agtatcactt caattggagt
    21421 ttaaaaatgg aggatttatt ttgaaagttc aattcaaaaa aaggattagt ttactcatca
    21481 tcatgtttgg gatcgcagtt tcctcactgg gtgttacaca ggcggttcat gcaaaagcaa
    21541 atacgagcga ttcaagggtg cattttactt tcagatggta cagcccttac gactatacaa
    21601 ctgctcgaag aa
//
