LOCUS       c00004_gnlPro..        22992 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IKPFODNH_12.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:17:58
            Original ID  :: gnl|Prokka|IKPFODNH_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 58499
            Orig. end    :: 81491
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22992
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[68499:71491]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12992
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..22992
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22992
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(794..2002)
                     /locus_tag="ctg4_61"
                     /transl_table=11
                     /translation="METQQRSTEYNFQGIMYFFRREKIQCRYQFSLRDAVDITLLQRAL
                     TAALASAPYYTQRLVQEKREMWLEPNTEPCLVYPGSTMRNIPEQANGYLFCVSCEGDTV
                     YFDWHHFLLDGHGVSPLLTSILEQYCNLRYGTAFAVPQIVCDPPYDMEAMLAEYPPVEY
                     GSDVIQRDVVQTYEGALRRTRVCLSKQSLVEKALANNAKPVSALMGLLCMAMREYLGKE
                     KIQYSYSSDTRDVAGVPNALYNCVCSFGHTVQLQAQTRLADFVADVDADIRRDLQPQSK
                     RRRMADQMGWVYKVNQQKAPLRIKQRVFQMGEYIGGTISDFWLSYLGNPLMPATPELAQ
                     YTTDFGVWVPPDGASVGVEAASLNGKIILCIHNKAPNPGLADILRKTFENEGVAVLEAE
                     DLD"
     CDS             complement(2009..2251)
                     /locus_tag="ctg4_62"
                     /transl_table=11
                     /translation="MERAEIISQITAILEDVAEVSPEDVTESSVLMDDLDLSSMEILTI
                     VADLEETFGLRIPEKELRNFVTMGDLVDYLAANVG"
     CDS             complement(2279..3748)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 213.8; E-value:
                     1.1e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_63"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-65, bitscore:
                     213.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKVLDNVYDLVTLNMEQRFSERVALRFYDKETDEVTAVHYKDYA
                     RDIRRAVNYFQSTIPDIKGKKICLLNKNSYEYAVNTFGIILAGGVLVLLNQHKSWDELS
                     YELGLVEPAAILTDGDDYGTKEQLQAAYGSILRPMDGFRAYEPVAEMPRCIGHDDLMIL
                     MFTSGTTGRSKGVMLSERNFFSVMRAHVQIGERMMEYKHDPELVVSQYTVLPMFHLGAF
                     ICLFSWAHGGWALNISGDIRNFYKEIRRMPSQVMAVVPVIMNSLHKDVMRGRKERLGEL
                     WVPICSSAMFDPQVMLDMATNGMFVVQTYGATETCGDGIINYAQDAKHIGAVGQGNDYL
                     DYKLEPDGELCIRGDSIMLGYYKDPEATAAVIDKDGWFHTGDLARVDEDGYYYITGRKK
                     NLIILDSGENVSPEELEGMLEKCPAVQECIVKELGKKIGVVVYCEKEHQQTVRDFIAQM
                     NRTVPLYKRIGVVEFSETPLPRNGAGKLVRK"
     CDS             4124..5239
                     /locus_tag="ctg4_64"
                     /transl_table=11
                     /translation="METTKPRTVNSIGMFDMLKGAGMLAIVLGHTAELYPLQLEGGLSL
                     TAFVGFIYRETLMAAFFIASGYGFRKRSISKCIHQQLKSLLKPFCYTAVFTTVLHFIIH
                     YKTFHYLPGSMTESIKVAGGFLLGLPHTATYFGQEFFSCGPMWYLLALLMGWILLDVIL
                     NIFPERYIPWAVGGAALLGWGASLVWELPFCLIQGAVITPYLYLGYLAKRQHWLDQPLS
                     RRMSCILWAAVLLIPAAALATRRTDCVSMAEWSLGPISILLDGLAGLLFIRLFLRWSQR
                     RNPLVRFFEAIGRRSLYIFCVHTVELIAIPWYLFAAKYADRPVLGISLQYILSLGSIWL
                     ICALLQRRRDLIIKLFPARRRTPQVHYAPRH"
     CDS             5306..6100
                     /locus_tag="ctg4_65"
                     /transl_table=11
                     /translation="MNHDAPMTPAAMQAHIAELEQQLKLSDEGVSQLAQRCLELEQQLL
                     ACQTELAKHSAEAENITLTLPQLFYDTGSGFSPRECLTATEDVYNELTHEVSVTFVLPE
                     DARAIRLDPGELACCITDLAISDERISFQSVNGLLLQEDSLLFLDVDPNLSLHCTTGFG
                     AGMKFAVNYHYYPLGRFLHEQPGKSLLRALNDLKLENAAAAQEAEEVLQASRAECMRLN
                     QQLLTLQGIQHEYQVSLETMRASSSWRLTAPLRRLLNLVRGH"
     CDS             6135..7742
                     /locus_tag="ctg4_66"
                     /transl_table=11
                     /translation="MYTSYSTLQRKQLSKQVYTDTQSTYLLVYAPGRHKALQAALQNQL
                     HRKFRLVTRLEDELTPDVAGVLLVSEDVECTPTALTYFAAALREGADLAVCDASFGFDG
                     STALYLSTRHLPGSSCALVSRALLDKVRAAARGKDSVTELLRLAHAMAQHSRCIPQALL
                     HFRRELCADDVFSAKGRRALILSHELTMTGAPIVLVSAVPVLRSLGFEVVVLGPSDEGS
                     LPLFLDAGAAVVTRPDCVTSSALWGLATSADFVLANTVVEAPVVNTLNGSFVPVLWWLH
                     DAFAGYPFISHSIPKALGKNVHLCAVGSHATAAMHSVRPDFAIEQLIYGLPDYAAEQFP
                     RYDISFAGGRPLFVTVGSLEHRKGPDIFCNAIRLLPSAVREKAAFLFVGKAADKGMYNA
                     VDSLVRDYPQTVFYRKRLERPEVKSLMEQCNCVVCASRDDPMPTFVTEGLIFGKPSIVS
                     EHTGTAGLVTEGVDGFLYKDDDPQQLADKLAWAIEHPEALAAMHGSCRCLYEQQFSNES
                     YVATLTRLVKELTDGEES"
     CDS             7921..8958
                     /locus_tag="ctg4_67"
                     /transl_table=11
                     /translation="MSQAAAQQPSRKKTVISLLVLLALTCIIVFTFKDHWAEITAALAQ
                     LSVWQVLAVLAVGLSYPLLEGCVAWVIVRSRLPQFKLWQGLDVGWCGTFGNVVTLGAGA
                     VPVQLYYLHRAGLPLGPGAGLMTLEYVFHKSTVLLYATVMLLLQHRWLAANTTGVMRYL
                     PMAYAVVAVIIVALVLLCVSPLVQCLARWLLGFLPKTEKWQQRRADWLEQLEVLGTESR
                     RLLADKPRCLKIFALQALKLFGLFCLPYLCIRFMGLSPLGFWQVQLLTSLMLFVSNALP
                     NVAGMGSIETAFLLVFGSFLEQGEVMSVLMLYRIASYYVVFAASAVGFFIAQRHLAQME
                     LPKEG"
     CDS             8963..9421
                     /locus_tag="ctg4_68"
                     /transl_table=11
                     /translation="MKSFHIPRTALFFILFALAAFAVLYRPIDLKALVRASSQGTLRTE
                     EVAHFGSTNDMDYHLLSMDSEAFQQTAELLSTVSCRKKLNQNYSAYTHDTFPVQSVTVS
                     FYDDAENQKFLLTVYSDGVCILNSAFVSVKYPGGGAAQLYEQLAGMGQ"
     CDS             10001..12253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_69"
                     /sec_met_domain="Gly_radical (E-value: 3.1e-40, bitscore:
                     129.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.3e-266, bitscore:
                     878.3, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQFEQWEGFEGRIWKEEVNVRDFIQKNYTPYDGDESFLAGPTEA
                     TDKLWGALQQLQKAERAKGGVLDMETEVVSSLTSYGPGYIDENLKDLEQIVGLQTDKPL
                     KRAFMPYGGIKMAEQACTTYGYQPSAELHKIFTDYTRTHNQAVFDAYTPEMKKARHTHI
                     ITGLPDTYGRGRIVGDYRRVALYGIDALIQFKQEDLANCGDGTMTDDVIRLREEIARQI
                     SALKGMKKMAEAYGYDISQPAKDAKEACQWLYFGYLAAIKTQNGAAMSVGRISTFLDIY
                     IQRDLDRGILTESQAQELIDHMVMKFRMVKFARIPSYNQLFSGDPVWATLEVGGIGMDG
                     RSMVTKNCYRFLHTLENMGPAPEPNLTVLYSSALPEAFKKYAAKVSVNTSSVQYENDDV
                     MKPVWGDDYSICCCVSATQTGKEMQFFGARANLAKCLLYAINGGVDEKSHEQCGPNYAP
                     ITSEYLTYDEVLPKYVQMLDWLAGLYVNVLNLIQYMHDKYYYEEAEMALIDTDVRRTFA
                     TGIAGFSHVIDSLSAIKYAKVKVVRDENGLATGFETEGDFPKYGNDDDRADEIGVWLLK
                     TFLEMIKKRHTYRNSEATTSILTITSNVVYGKYTGALPDGRAAFTPFAPGATPSYGAEQ
                     NGLLASLNSVAKLPYHWALDGISNTQTINPEALGHSEGERVENLVQVLDGYFDQGAHHL
                     NVNVFGKEKLLDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVLARTCHGVL"
     CDS             12240..12992
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 62.7;
                     E-value: 1.4e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_70"
                     /sec_met_domain="Radical_SAM (E-value: 9e-29, bitscore:
                     93.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASCKALGYVHSLESFGSVDGPGVRFVVFLQGCALRCKYCHNPET
                     WAEGGEAWTAEALFQRVYRYRNYWGKKGGITVSGGEPLRQMDFLTEFFTLARAKGVHTA
                     LDTAGQPFRPDDPAYLAAFDRLMANTSLVILDLKEIDPERHRQLTGKDNANILAMARHI
                     SDLGIPLWVRHVLVPGLTDDEEGLRKTADFIRSLKTVQRVEVLPYHTLGLFKWQKLGIP
                     YPLPDAVPPTAEQVKRAEDLLEVSRYPG"
     CDS             13412..14809
                     /locus_tag="ctg4_71"
                     /transl_table=11
                     /translation="MQIFNTLTRQKEEFVPQVPGEYRIYVCGPTVYNYIHIGNARPLIV
                     FDTLRRYLEYRGNKVIYVSNITDIDDKLIKKGQEEGTSMKEVAQRFEAEYLKDAAGLNC
                     EKPTVQPRATEHIPQILDIVKDLIDSGHAYVAKNGDVYFRVKSDPGYGKLSHLNLDDLE
                     SGNRELRSRMEDDLKEDPADFAIWKAAKPGEPAWESPYGMGRPGWHIECSAMSRTHLGK
                     TIDLHCGGQDLIFPHHENEIAQSECANGCEFARYWMHNGFINVDNQKMSKSLHNFFTVR
                     DVANLYGYEPIRYFMLTAGYRMPLNYTVDLIESCKNSLERLYTCRENLDFALSKTDFGT
                     DETLKEKAAEARTKFCTAMDDDLNTPDALASVFDLVKEINTLSATSSKAALETAAAAFD
                     EITGVLGLLYNRKKDEVPAEVTALVEKRAAAKKAKDWATADAIRAQLTELGWAVKDTAQ
                     GPQLSKL"
     CDS             complement(14969..16186)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     335.1; E-value: 1.4e-102)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_72"
                     /sec_met_domain="Fe-ADH (E-value: 2.2e-102, bitscore:
                     335.1, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARFTLPRDLYHGKGALEALKSFTGKKAMICVGGGSMKRFGFLDR
                     AVEYLKEAGMEVELFEGIEPDPSVETVMRGAEAMLKFEPDWIIAMGGGSPIDAAKAMWI
                     KYEYPEITFEEMCKVFGIPPLRRKAHFCAISSTSGTATEVTAFSIITDYQKGIKYPIAD
                     FEITPDVAIVDPDLAETMPKKLVAHTGMDAMTHAVEAYVSTAHCDYTDPLAIFAIRMIQ
                     GDLVDSYNGDMSKRDSMHNAQCLAGMAFSNALLGIVHSMAHKTGAAFADYGAHIIHGAA
                     NAMYLPKVIAFNAKDPEAKKRYGVIADEMKLGGANDDEKVKLLIEYLRGMNDALNIPHC
                     IQHYGPDSYPTEQGFVPENVFLERLPEIAKNAIADACTGSNPRQPSQEEMEKLLKCCYY
                     DTEVDF"
     CDS             complement(17027..17500)
                     /locus_tag="ctg4_73"
                     /transl_table=11
                     /translation="MKFSTKSRYALRLMAELARYAPGTTVSLKEISERQNLSLKYLEQI
                     VTPLARVGLVKSERGSQGGYRLTKDPADYTAGEILRAIEGSVAPIPCLGSVTNECPMSE
                     QCFTLPFWAGLDEVINQYIDSVTLEQLASQLPAPDSAAQESCCSCGGAKNENK"
     CDS             17633..17956
                     /locus_tag="ctg4_74"
                     /transl_table=11
                     /translation="MTEKITAADAIRLLDTGKAVAVDVREPDEYAVGHIPGAKLLPLGQ
                     VIDRAAEVLPDKNALWLVYCRTGRRSADAVQKLEALGYTHLRDLGGILSWPYEIEGDFE
                     GHF"
     CDS             18009..18449
                     /locus_tag="ctg4_75"
                     /transl_table=11
                     /translation="MSFHAKEFAGSHCGCRYQQDYRPTLGRDGKKESGTLEVIKFYYDG
                     AIRFEQHCYGEAATFVFGVWASGMDEDGTLNWVLPDRRKSYYDESYLPKKLDRVDEAGN
                     LYFDGGIFPWKLADDFAEDKRWGYPKWKVALGKLTGKGKKGD"
     CDS             18583..19800
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_76"
                     /sec_met_domain="Aminotran_5 (E-value: 1.6e-82, bitscore:
                     270.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENMEKVVYLDNAATTPCAPEALEMMVKALSGACGNPSSHYSIGY
                     EAKEFVDTGRAQVAKAINASPAELFFTSCGSEADNWAVKGTAFTKARQNKKHLITSAFE
                     HHAIMHSMAALERMGFEVTYIRPTSEGYIRPEDVEAAIRPDTALVSIMMANNEIGTIQP
                     IKEIAEVAHKHGVWMHTDAVQAVGAIPVDVKELGVDMLSMSAHKFNGPKGMGALYCRKG
                     VWPQNLIDGGSQEARHRAGTENVAGIAAMGKALEIATAHLDERMAHESELRDYVIDRIL
                     KNIPEARLNGGRSPRLPNNVNISFPGLEGETILLDLDMHGICASTGSACNSDSLDPSHV
                     LLSIGLPEEIGHGSMRFTFGPQNTMEEAKYLCDVLEEVIPRRRAMSCMWLQGQNKARQF
                     SLKGEQ"
     CDS             19803..20246
                     /locus_tag="ctg4_77"
                     /transl_table=11
                     /translation="MASMYSAKVMEHFANPHNVGELPDANGVGEVGNPKCGDIMRMYLK
                     IENNVIVDVKFLTFGCGAAIATSSMATDLIKGKTVDEALKLTNKAVVEALEGLPPVKVH
                     CSVLAEQAVKAALSDYYRRQGIDPEPIVGKLEEDCEHCESCGN"
     CDS             complement(20385..21923)
                     /locus_tag="ctg4_78"
                     /transl_table=11
                     /translation="MNIKRAKEEIEHTVKAYLAKDALGEYAIPAIRQRPILLMGPPGIG
                     KTQVMEQVARECGVALVAYTITHHTRQSAVGLPFIRQRHYGDKDVSVTEYTMSEIIASI
                     YAKMEATGLSEGILFIDEINCVSETLAPTMLQFLQCKTFGNQAVPAGWVIVAAGNPPEY
                     NKSVRDFDIVTLDRVRRMDIEPDLPVWKDYARAAHIHSAILSYLELHPQNFYQINADVD
                     GTQFVTARGWEDLSNLLDTYEALGLQADEELIREYIQHPKIAEDFSAYLDLYYKYRDDY
                     GVEEILAGQAKPAVFARLLQAPFDERLSLVSLLLAGLDTRFTASLQADAVADACYAFLR
                     ETKKALAALPEDIPDGSAELFSQQIKDYEAETQQKRDAGLLGKAELTNRLQVQAALHQW
                     EGELRRANAAGTQEAFDLLRGQFGALADQREAAQKTAAAALEAAFDFMEQAFAESQEMV
                     VFVTELTVNPASHQFLTENGCERYFKYNKDLLLDHRKAALQQELAAEQRRHGGV"
ORIGIN
        1 ggcgttctgg aagaacagca gcccggtcag cagccagaag cgggcagagc gcagaaagct
       61 ccagtcgatg gcttccttct cggcgctgct tttactcttg ccgccgcgca gcggggtaaa
      121 aacgtacacc agccagagca caaggcccac ggctgccagc agaaagaccg ccagctcggt
      181 gcttacccgg gctgccgccg caatgaggaa ggggcacagc agtgcgccgc aggcgtagca
      241 gctgtgcatc aggttcatgc cccgggtgcg gtcggcggag tgatcactga ccagaatggt
      301 acaggtgttg ataacgctgc ccttagcgat gcccaccaca aaaaaggccg ctgccagcag
      361 caccactgcg ccggtcagcc ccatgacggc gtagcccacc gcatagccga tggtcagcag
      421 cagcacactg cgtttcatgc ccagcgcact gggcagcatg cccatcagca gccctgccag
      481 caggttgccc acgctcatca gggagagcag tgtaccggtc atgccgtagg caaagccgta
      541 gcgctcctgc agcagactga ccaccacacc tgcgctgatg gcacagatgc cgctgaagaa
      601 aaaggtcgca aagcccgcat tgcgcaggcg cgtgttctgt tgttccatgg tgttcctctc
      661 cttgcggaaa tatcctttct ctatttaacc attttttcgc atctttgcaa ccggattttc
      721 ttacaaaaag cagcaaaaaa actgccgcac aaaaaacgtg cagcagccct tttgctttta
      781 taataagtat ttctcagtcc agatcttcgg cttccagcac cgcaacgcct tcgttttcaa
      841 aggtcttgcg gaggatatca gccagacccg ggttgggtgc cttgttgtgg atgcacagaa
      901 tgatctttcc gttcaggctg gcagcctcca cgcccacgga tgcaccgtcc ggcggcaccc
      961 agacgccaaa atccgtggtg tactgtgcca gttccggagt ggcgggcatg agcggattgc
     1021 ccagatagct gagccagaaa tccgaaatcg tgccgccgat gtactcgccc atctggaaca
     1081 cccgctgctt gatgcgcagg ggtgcctttt gctggttcac cttgtacacc cagcccatct
     1141 ggtcggccat gcggcggcgc ttggactgcg gctgcagatc ccgcctgatg tctgcatcta
     1201 catcagccac aaaatccgca aggcgggtct gggcttgcag ctgcaccgta tgcccgaaac
     1261 tgcacacgca gttgtacagc gcgttcggca caccggccac atcgcgggta tcggaggagt
     1321 aggaatactg gatcttctcc ttgcccagat actcccgcat ggccatacac agcagaccca
     1381 tcagagcgct taccggcttt gcgttgttcg ccagcgcttt ttccacaagg ctctgcttgc
     1441 tcaggcacac ccgggtgcgg cgcagcgcac cctcgtaggt ctgcaccaca tcccgctgga
     1501 tgacatcgct cccgtactcc acaggcgggt actctgccag catggcctcc atatcatagg
     1561 gcgggtcgca cacgatctgc ggcaccgcaa aggccgtgcc gtaacgcagg ttgcagtact
     1621 gctccagaat gctggtgagc aggggcgata ccccgtggcc gtccagcagg aagtgatgcc
     1681 agtcaaagta gacggtatcc ccttcgcagc tgacgcagaa caggtagccg ttcgcctgtt
     1741 ccgggatatt gcgcatggtg ctgccggggt acacaaggca gggctccgta ttgggctcca
     1801 gccacatctc ccgcttttcc tgcaccagac gctgggtata atagggcgca cttgccaagg
     1861 ccgctgtcag tgcccgctgc aaaagggtga tatccaccgc atcccgcagc gagaactggt
     1921 accggcactg gatcttttcc cgacggaaaa agtacatgat tccctgaaag ttatattccg
     1981 tcgagcgctg ctgtgtttcc attggttttt accccacgtt tgctgccaga taatccacca
     2041 gatcacccat ggtgacaaag ttgcgcagct ccttttccgg gatgcgcagg ccaaaggtct
     2101 cttcaagatc tgccacaatg gtcaggatct ccatagagga cagatccaga tcgtccatca
     2161 ggacgctgct ttcggtcaca tcctccggcg atacctctgc gacatcctcc agaatagccg
     2221 tgatctgaga aatgatttct gcacgttcca tcgtattatg cttcctttct gttgcgtatt
     2281 acttgcgcac cagcttgcct gcgccgttgc ggggcagcgg cgtttcgctg aattccacca
     2341 cgccaatgcg cttgtacagc gggacggtgc ggttcatctg ggcaataaag tcccgcaccg
     2401 tctgctggtg ctccttttca cagtatacca caacacctat ctttttgccc agttctttta
     2461 cgatacattc ctgtacggca ggacattttt ctaacatgcc ctccagctct tcggggctga
     2521 cgttctcgcc gctgtccaga atgatcaggt tcttcttgcg gccggtaatg tagtagtagc
     2581 cgtcctcgtc cacccgggca aggtcgccgg tgtggaacca gccgtccttg tcgatgaccg
     2641 cagcggtggc ctcggggtcc ttgtagtagc ccagcatgat gctgtcgccc cggatgcaca
     2701 gttctccgtc cggctcgagc ttgtaatcca gataatcgtt gccctgtccc acagcgccga
     2761 tgtgctttgc atcctgcgcg tagttgatga tgccgtcgcc gcaggtctcg gtagcgccgt
     2821 aggtctgcac cacgaacatc ccgttggtgg ccatatccag catcacctgc gggtcaaaca
     2881 tcgcagagga gcagatgggc acccacagct cgcccaagcg ctccttgcgg ccgcgcatca
     2941 cgtccttgtg cagggagttc atgatcaccg gcaccaccgc catgacctga ctgggcatcc
     3001 gccggatctc cttatagaag ttgcggatat cgccgctgat gttcagcgcc cagcccccgt
     3061 gtgcccaaga gaacaggcag atgaatgcac ccagatggaa catgggcagc accgtgtact
     3121 ggctgaccac aagctccggg tcgtgcttat actccatcat gcgctcaccg atctgcacat
     3181 gggcgcgcat cacgctgaag aagttgcgct cgctcagcat cacgcccttg ctgcgtccgg
     3241 tggtgccgga ggtgaacatc aggatcatca ggtcatcgtg gccgatgcag cggggcatct
     3301 ctgccaccgg ctcataagcg cggaagccgt ccatggggcg caggatgctg ccgtaggcgg
     3361 cctgcagctg ctccttggtg ccgtagtcgt cgccgtcggt caggatggcg gcgggttcca
     3421 ccagccccag ctcgtaggac agctcgtccc agctcttgtg ctggttgagc agtaccagta
     3481 cgccgcccgc cagaatgatg ccgaaggtgt tcacggcata ttcgtagctg tttttattca
     3541 gcaggcagat ctttttgccc ttgatatccg ggatggtgct ctggaagtag ttgaccgcac
     3601 ggcggatgtc ccgcgcgtag tccttataat ggactgcggt cacctcgtcc gtttccttat
     3661 cataaaagcg gagcgccaca cgctccgaaa aacgctgttc catattcagg gtgaccagat
     3721 catacacgtt gtccaatacc ttgatcattg tattttcctc ctgcgttgtt atttcatcct
     3781 gcggcagtgc gctgtactgt gctcagtata caatattttc caatgcaatg caatacttct
     3841 gcaacattta atttctcact ttgacaactt tcaattgcac atcttgggat acgccccggc
     3901 caaattctac ctttcgttgc aatccgccgg ttttcgtgct acaattttta gcgcaaaata
     3961 ccagttccgg tatggtgcag actgcaaaac aaaattgaca gtctctataa aaagcattat
     4021 actagccata tatcatggca atgctgtata aaaactgatc atttgcgccg tatccggctt
     4081 ttttctcgag gggtattggc ccggcgcagg gaaggaatct ttcatggaaa caaccaagcc
     4141 ccgcactgtc aactccatcg ggatgtttga tatgctcaag ggcgctggga tgctggccat
     4201 cgtgctgggg cacactgcgg agctttaccc actccagctg gagggcggtc tgtcgctgac
     4261 ggcctttgtc ggctttatct accgcgaaac gctgatggca gcctttttta ttgccagcgg
     4321 ctacggcttc cgcaagcgct ccatcagcaa gtgcatccac cagcagctca aaagcctgct
     4381 caagcccttt tgctacactg cggtgttcac cacggtgctg cacttcatca ttcattataa
     4441 aacctttcac tatctgcccg gctccatgac tgagagcatc aaggtggcgg gcggctttct
     4501 gctgggtctg ccccatactg ccacctactt cgggcaggag ttcttttcct gtgggcccat
     4561 gtggtatctg ctggcgctgt tgatgggctg gatcttactg gacgttatcc tgaacatctt
     4621 cccggagcgg tacatccctt gggcggtggg cggtgccgcc ctgctgggct ggggtgccag
     4681 ccttgtatgg gagctgccct tctgcctgat ccagggcgcg gtgatcacgc cgtacctgta
     4741 ccttggctac cttgccaaac ggcagcattg gctggatcag cctttgtccc gccggatgtc
     4801 ctgcatcctg tgggcagccg tactgctgat cccggcagcc gcccttgcca cccgccgcac
     4861 cgactgtgta tccatggccg agtggtcgct gggccccatc agcatcctgc tggacggcct
     4921 tgccggtctg ctgtttatcc ggctgttttt gcgctggagc cagcgccgca acccgctggt
     4981 gcgctttttc gaggccatcg gccgccgttc tctgtacatc ttctgcgtac atacggtgga
     5041 gctgattgcc attccgtggt atctgttcgc cgccaaatac gctgaccgcc ctgttttggg
     5101 catcagcctg caatacatcc tttcgctggg ctccatctgg ctgatctgcg ccctgctgca
     5161 gcggcggcgg gatctgatca tcaagttgtt ccccgcccgg cggcgcaccc ctcaggtaca
     5221 ttacgccccg cggcactgat ttttctgaat gttttggctg cggcggtgca gctgttatag
     5281 gataaaggaa gaggaggatc ccgttatgaa ccacgatgcc cccatgaccc ctgctgccat
     5341 gcaggcgcac attgccgagc tggagcagca gctcaagctt tcggacgagg gtgtttccca
     5401 gctggcgcag cggtgtctgg agctggagca gcagctgctg gcttgccaga ccgagcttgc
     5461 caagcacagc gccgaggctg agaatatcac ccttaccctg ccgcagctgt tctacgacac
     5521 cggcagcggc ttttcgcccc gggaatgcct gactgccacc gaggatgtct acaacgaact
     5581 gacccacgag gtctcggtca cctttgtcct gccggaggac gcacgcgcca tccgtctgga
     5641 ccccggcgag ttggcctgct gcatcaccga ccttgccatc tcggacgagc gcatcagctt
     5701 ccagtcggtc aacggccttc tgctgcagga ggacagcctg ctgtttttgg acgtagaccc
     5761 caacctttcg ctgcactgca ccaccggctt tggtgccggc atgaagtttg cggtgaacta
     5821 tcactactac ccgctgggac gttttctgca cgagcagccc ggcaagtctc tgctgcgggc
     5881 gctgaacgac ctgaagcttg agaacgccgc tgccgcgcag gaggcagagg aagtattgca
     5941 ggccagccgc gccgagtgta tgcggctgaa ccagcagctg ctgaccttgc agggcatcca
     6001 gcacgaatat caggtttcgc tggaaacgat gcgcgccagc agcagctggc ggctgaccgc
     6061 cccgctgcgc agactgctga acctagtgcg cggtcactga gcccgcccga tattctgccc
     6121 ggaggagttg gatcatgtac accagttaca gtaccctgca gcgcaagcaa ttgtccaagc
     6181 aggtctatac cgatacccag agcacctatc ttctggtcta tgcgccgggg cgtcacaagg
     6241 cgctgcaagc ggcgctgcaa aaccagctgc accgcaagtt ccgtctggtg acccggcttg
     6301 aggacgagct gacccccgat gtagccgggg tgctgctggt aagcgaggat gtggagtgca
     6361 cccccaccgc cctgacttat tttgccgccg ccctgcggga gggcgcagac cttgcggtct
     6421 gcgacgcctc ctttggcttt gacggctcca ccgccctgta cctgagcacc cggcacctgc
     6481 ccggcagcag ctgcgcactg gtgtcccgcg cattgctgga caaggtacgc gccgccgccc
     6541 ggggcaagga cagcgttacc gaactgctgc gtctggccca cgccatggcg cagcacagcc
     6601 gctgcatccc gcaggcgctg ctgcacttcc gccgggagct gtgcgccgac gatgtattct
     6661 ctgccaaggg acgccgtgcg ctgattttga gccatgagct gaccatgacc ggtgcgccca
     6721 tcgtgctggt aagtgccgtg ccggtgctgc gcagcttagg ctttgaggtg gtggtgctgg
     6781 ggccctcgga tgaaggctcg ctgccgctgt ttctggacgc cggggccgct gtggtcaccc
     6841 gcccggactg cgttacttcc agcgccctgt gggggctggc caccagcgca gactttgtgc
     6901 tggccaacac ggtggtggaa gcgccggtgg tgaacaccct gaacggctcc tttgtgccgg
     6961 tgctgtggtg gctgcacgat gcctttgcgg gctacccctt catctcccac agcatcccca
     7021 aggcgctggg caaaaacgtg cacctctgcg ccgtaggctc ccacgccacc gccgccatgc
     7081 actccgtccg gccggatttt gccatcgagc agctgatcta cggtctgccg gactatgcag
     7141 ccgagcaatt cccccgctat gacatcagct ttgccggggg gcgtcccctc tttgtgacgg
     7201 taggctcgct ggagcaccgc aagggtccgg acatcttctg caacgccatc cggctgctgc
     7261 cctctgcagt gcgggaaaaa gctgccttcc tttttgtggg caaagccgcc gacaagggga
     7321 tgtacaacgc cgtggacagc ttggtgcggg actatcccca gaccgttttc taccgcaagc
     7381 ggctggagcg cccggaggtc aaatccttga tggagcagtg caactgcgtg gtgtgcgcct
     7441 cccgggatga ccccatgccc accttcgtca ccgagggact gatcttcggc aagccctcca
     7501 tcgtatcgga gcacaccggc accgccgggc tggtgaccga aggcgtggac ggcttcctct
     7561 acaaggacga cgacccgcag cagctggccg acaagctggc ctgggccatc gaacacccgg
     7621 aggcgctggc cgccatgcac ggcagctgcc gctgcctgta cgagcagcag ttctccaacg
     7681 aatcctatgt cgccaccctg acaaggctgg taaaagagct gacggacggg gaagaatcat
     7741 gaaaaaaaca ctgccggaca gctgcacgct gcccggcagt gctttttcac gggagaggtt
     7801 ttcccatttt atcaaatccc ccaaattgcc caacaaagtt ccgcttccgt tcacaaaggg
     7861 cggcgggaga tgtgctatac tggttccaga atttccggtt gtgaaaggag ttttgtttcc
     7921 atgagccaag ccgccgcgca gcaaccctcc cgcaaaaaga ccgtgatctc tctgctggtg
     7981 ctgctggcac ttacctgcat catcgtgttc acttttaagg accactgggc cgagatcact
     8041 gcggcgctgg cacagctgtc ggtgtggcag gtgctggcgg ttctggcggt cggcctcagc
     8101 taccccctgc tggaagggtg cgtggcgtgg gtcatcgtgc gcagccgtct gccgcagttc
     8161 aagctgtggc aggggctgga tgtgggctgg tgcggcacct ttggcaacgt ggtcacgctg
     8221 ggtgccggtg cggtgccggt gcagctgtac tacctgcacc gggccgggct gccgctgggc
     8281 cccggcgcag ggttgatgac gctggaatac gttttccaca agagcacggt gctcctgtac
     8341 gccaccgtga tgctgctgtt gcagcaccgc tggcttgctg ccaacaccac cggtgtcatg
     8401 cggtatctgc ccatggcata cgctgtggta gcggtaatta tcgtggcgct ggtgctgctg
     8461 tgcgtctcgc cgctggtgca gtgcctcgcc cgctggctgc tgggctttct gcccaagacc
     8521 gaaaagtggc agcagcgccg cgccgactgg ctggaacagc tggaggtgct gggcaccgag
     8581 agccgccgcc tgctggcaga taagccccgc tgcctgaaga tttttgccct gcaggcgctc
     8641 aagctgttcg ggctgttctg cctgccctac ctgtgcatcc gtttcatggg gctttccccg
     8701 ctgggcttct ggcaggtgca gctgctcacc agcctgatgc tcttcgtctc caatgccctg
     8761 cccaatgtag ccgggatggg ctcgatcgag accgcctttc tgctggtgtt cggcagcttt
     8821 ctggagcagg gcgaggtgat gagcgtgctg atgctctacc gcatcgccag ctattatgtg
     8881 gtatttgccg ccagcgccgt gggctttttc atcgcccagc ggcatctggc gcaaatggaa
     8941 ctgccaaagg aggggtgagc agatgaaaag cttccacatt ccccgcaccg ctttattttt
     9001 tatcctgttt gcactggcag cttttgcggt gctgtaccgt cccatcgacc tgaaggcgct
     9061 ggtgcgcgcc agctcgcagg gcacgctccg caccgaggaa gtggcgcatt ttggcagcac
     9121 aaacgacatg gactatcacc tcctctccat ggacagcgaa gcgttccaac aaacggcaga
     9181 attgctttcc accgtctcct gccgcaaaaa gctgaaccag aactattctg cctacaccca
     9241 cgataccttc ccggtgcagt cggtcaccgt cagcttttat gacgatgccg agaaccagaa
     9301 gtttctgctg acggtgtatt ctgacggcgt gtgcatcctg aacagcgcct ttgtcagcgt
     9361 aaaatacccc ggcggcggcg cagcgcagct gtatgaacag ctggcgggga tggggcagta
     9421 aaaacaaaaa acggggcgtg caggtggtca agctgcacgt cccgtttttg ttttctttgc
     9481 gtcggctgtg gtaccaaaca cagccggtgc cgcgccggaa gcagcagagc aaaccgtgct
     9541 gccgcttccc gtagaaaaga gaaaggaatg gaggaatgga gcggagcgct tgcagacgct
     9601 ccttttttct ggtgcaacgt ggttagaatt agctaaccgc cgctgcgaga acaggatacc
     9661 acagtcagtt agtcttgtca acccttaatt tgcaaatttt ttcgcaaagt tgccgtgccg
     9721 ccggggtttc tgccgttttt ctacattctg cccaaagaat agcctttccg ctggaagaaa
     9781 acccacttgt tttctattgc tttttaaaac ggttcttgct attataataa cgcaagattt
     9841 tgtgggcagg tttttatttt tgtctacacc ttgtagtaag ggctgccgca gacggcagca
     9901 caagaccgtt tcgcccccag aaaaccgccc agacagagcg gtttttcaaa ggctcattag
     9961 ttagaaagcg ctaactgcgt aatggagcaa ggaggttcca atgatccagt ttgaacagtg
    10021 ggaaggcttt gaaggccgca tctggaagga agaggtcaat gtgcgtgact tcatccagaa
    10081 gaactacacc ccctatgacg gcgacgaaag ctttctggca ggccccaccg aggctaccga
    10141 taagctttgg ggtgctttgc agcagctgca gaaggccgag cgcgccaagg gcggcgtgct
    10201 ggatatggag accgaggtgg tcagcagcct gacctcctac ggccccggct atattgacga
    10261 aaacctgaag gatctggagc agatcgttgg cttacagacc gacaagcccc tcaagcgcgc
    10321 ctttatgccc tacggcggca tcaagatggc agagcaggcc tgcaccacct acggctacca
    10381 gccctctgcc gagctgcaca agatctttac cgactacacc cgcacccaca atcaggccgt
    10441 gttcgatgcc tacaccccgg agatgaagaa ggcacgccac acccacatca tcaccggtct
    10501 gccagacacc tatggacgcg gccgcatcgt gggcgactac cgccgcgttg ccctgtacgg
    10561 cattgacgcc ctgatccagt tcaagcagga ggatcttgcc aactgcggcg acggcaccat
    10621 gaccgatgac gtcatccgcc tgcgcgagga gatcgcccgc cagatcagcg ccctgaaggg
    10681 catgaagaag atggccgagg cttacggcta cgacatctcc cagcccgcca aggacgccaa
    10741 ggaggcctgc cagtggctgt acttcggcta tctggccgcc atcaagaccc agaacggcgc
    10801 cgccatgagc gtgggccgca tctccacctt ccttgacatt tatatccagc gcgatctgga
    10861 caggggcatc ctgaccgaaa gtcaggcaca ggagctcatc gaccacatgg tcatgaagtt
    10921 ccgcatggtc aagtttgccc gcatccccag ctacaaccag ctgttctccg gcgaccccgt
    10981 gtgggcgacc ctggaggtgg gcggcatcgg catggacggc cgcagcatgg tcaccaagaa
    11041 ctgctaccgc ttcctgcaca cgctggaaaa catgggcccc gcaccggagc ccaacctgac
    11101 cgtgctgtac tcctctgccc tgcccgaggc ctttaagaag tacgccgcca aggtgtccgt
    11161 caacaccagc agcgtccagt acgagaacga cgatgtgatg aagcccgtct ggggcgacga
    11221 ttactccatc tgctgctgcg tgtctgccac ccagaccggc aaggagatgc agttcttcgg
    11281 cgcacgcgcc aaccttgcca agtgcctgct gtacgccatc aacggcggcg tggatgagaa
    11341 gagccacgag cagtgcggcc ccaactatgc tcccatcacc agcgagtacc tgacctatga
    11401 cgaggtgctg cccaagtatg tgcagatgct ggactggctg gccgggctgt acgtcaacgt
    11461 gctgaacctc atccagtata tgcacgacaa gtactactac gaggaagccg agatggcact
    11521 catcgacacc gatgtgcgcc gcacctttgc caccggcatt gcaggcttct cccatgtcat
    11581 cgactccctg agcgccatca agtacgccaa ggtgaaggtg gtgcgcgacg agaacggcct
    11641 tgccaccggc tttgagaccg agggcgactt ccccaagtac ggcaacgatg acgaccgcgc
    11701 cgacgagatc ggcgtgtggc tgctcaagac cttccttgag atgatcaaga agcgccacac
    11761 ctaccgcaac tccgaggcta ccacctccat cctgaccatc acctccaacg tggtgtacgg
    11821 caagtacacc ggcgctctgc cggatggccg cgccgccttc accccgtttg cacccggcgc
    11881 tacccccagc tacggcgcag agcagaacgg tctgctggcc tcgctgaact ccgtggcaaa
    11941 gctgccctac cactgggcgc tggacggcat ctccaacacc cagaccatca accccgaggc
    12001 actgggtcac agcgagggcg agcgcgtgga gaatctggtg caggtgctgg atggctactt
    12061 cgatcagggc gcacaccacc tgaacgtgaa tgtctttggc aaggagaagc tgctggatgc
    12121 catggagcac cctgagaagg aagagtacgc caacttcacc atccgcgttt ccggctacgc
    12181 tgtcaagttc atcgacctga cccgcgagca gcagctggac gtgctggcac gcacctgcca
    12241 tggcgtcctg taaggccctt gggtacgtcc actcgctgga atccttcggc tcggtggacg
    12301 gccccggcgt gcgctttgtg gtgtttttgc aggggtgtgc cctgcggtgc aagtactgcc
    12361 acaaccccga aacatgggca gagggcggcg aggcgtggac ggcagaagcg ctgttccagc
    12421 gggtataccg ctaccgcaac tactggggca aaaagggcgg catcacggtc agcggcggcg
    12481 agccgctgcg gcagatggac tttctgaccg agttcttcac gctggcacgc gccaagggcg
    12541 tgcacacggc gctggacacc gccgggcagc ccttccgccc ggacgacccg gcgtatctgg
    12601 cggcatttga ccgcctgatg gctaacacca gtctggtgat tttagacctc aaggagatcg
    12661 acccggagcg ccaccggcag ctcaccggca aggacaacgc caatatcctt gccatggcgc
    12721 ggcacatctc cgacctcggc atcccgctgt gggtgcggca cgtccttgtg cccgggctga
    12781 ccgatgacga ggaagggctg cgcaaaacag cagactttat ccgcagcctg aaaacggtgc
    12841 agcgggtgga ggtgctgccc taccacacct tggggctgtt caagtggcag aagctgggca
    12901 tcccctatcc cctgccggac gcagtaccgc ccacggcaga gcaggtaaag cgcgcagagg
    12961 atctgctgga agtaagccgg tatcccgggt aaagaggaaa gcatcttttt gatttgaaat
    13021 tcagccaagc cggtaggctt ggctgaattt cattttcaca ggtttgttct gccttgactt
    13081 ccctgcaccg caccgctata ataaaggggt aaaaggataa atgcgtttat ccgggcagag
    13141 tagcgccgca caccgtctgc gcagagagaa caggccactg gctggaagcc tgtttgcaga
    13201 ccgctgcgca aagtgcgccc ggacagcacg cggcgggaac cccgtgggga agtatcgccg
    13261 tgcggtgcgc cgccgttacc ggctttgagc gacaaacaga agtggaaccg cgattttgat
    13321 tttaaaaccg ccttcggagc tgtgccttgt gcaccgctcc gggggcgttt tgttttgcgg
    13381 cttctgtttg gaacaaaaag gagaattgac catgcagatc ttcaacaccc tgacccgaca
    13441 gaaggaagaa tttgtgccgc aggtgcccgg cgagtaccgc atctacgtct gcggccccac
    13501 cgtgtacaac tatatccaca ttggcaacgc acgcccgctg atcgtgttcg ataccctgcg
    13561 ccgctatctg gaataccggg gcaacaaggt gatctacgtt tccaacatca ccgatatcga
    13621 tgataagctc atcaagaagg ggcaggaaga gggcacctcc atgaaggagg tggcgcagcg
    13681 ctttgaggcc gagtacctga aggatgccgc cggtctgaac tgtgaaaagc ccaccgtgca
    13741 gccccgcgct accgagcata tcccccagat tttggatatc gtcaaggatc tgatcgactc
    13801 cggccacgcc tacgttgcca agaacggcga tgtgtacttc cgggtgaaga gcgaccccgg
    13861 ctacggcaag ctgagccacc tgaatctgga cgatctggag agcggcaacc gcgagctgcg
    13921 cagccgcatg gaggacgatt tgaaggaaga ccccgccgac tttgccatct ggaaggctgc
    13981 aaagcccggt gagcccgcat gggaaagtcc ctacggcatg ggccgcccgg gctggcacat
    14041 tgagtgcagc gccatgagcc gcacccatct gggcaagacc atcgacctgc actgcggcgg
    14101 tcaggatctg atcttccccc accacgaaaa cgagatcgcc cagagcgagt gcgccaacgg
    14161 ctgcgagttt gcccgctact ggatgcacaa cggcttcatc aacgtggaca atcagaagat
    14221 gtccaagagc ctgcacaact tctttaccgt gcgggatgtg gcaaacctct acggctacga
    14281 gcccatccgc tacttcatgc tgaccgccgg ctaccgcatg cccctgaact acaccgtgga
    14341 tctcatcgag agctgcaaga acagtctgga gcgcctgtac acctgccgcg agaatctgga
    14401 ctttgccctg agcaagaccg acttcggcac cgacgagaca ctgaaggaaa aggccgccga
    14461 ggcacgcacc aagttctgca ccgccatgga cgatgacctg aacaccccgg atgcactggc
    14521 ctccgtgttc gatctggtca aggagatcaa caccctgtct gcaacttcca gcaaggctgc
    14581 actggagacc gctgccgccg cctttgacga gatcaccggt gtgctgggtc tgctgtacaa
    14641 ccgcaagaag gacgaggtgc ccgccgaggt gaccgcgctg gtagagaagc gcgctgccgc
    14701 caaaaaggcc aaggactggg ccaccgctga tgccatccgc gcacagctga ccgaactggg
    14761 ctgggctgtc aaggacaccg cacagggtcc ccagctgagc aagctgtaac accttagtag
    14821 tataaaaggg gttcggaaac gccgtaggcg tttccgaacc ccttttttca cgggagaatg
    14881 caggcgaaaa cggcaaaagc cccgcagggc ggtatgctct gcggggcttt tgtccatagg
    14941 aaaggaggcg taataaagaa aggacggatt agaaatccac ctcagtatcg tagtagcagc
    15001 acttgagcag cttctccatc tcctcctgac tgggctggcg ggggttggag ccggtgcagg
    15061 cgtcggcgat ggcgttcttg gcaatctcgg gcagacgctc caggaacaca ttctccggca
    15121 caaagccctg ctcagtgggg taggagtccg ggccgtagtg ctggatgcag tgggggatgt
    15181 tcagcgcgtc gttcatgccg cgcaggtact cgatgagcag cttgaccttt tcgtcatcgt
    15241 ttgcgccgcc cagcttcatc tcgtctgcga tgacgccgta gcgcttcttg gcctccgggt
    15301 ccttggcgtt gaaggcgatg accttgggca ggtacatggc gttggccgca ccgtggatga
    15361 tgtgtgcgcc gtagtctgca aaggcagcgc cggtcttgtg tgccatggag tgcacgatgc
    15421 ccagcagtgc gttggagaag gccataccgg caaggcactg ggcgttatgc atggagtcgc
    15481 gcttggacat atcgccgttg tagctgtcca ccagatcgcc ctgaatcatg cggatggcga
    15541 agatggccag cgggtcggtg tagtcacagt gtgcggtgga aacgtaagcc tccacggcat
    15601 gggtcatggc gtccataccg gtgtgggcaa ccagcttttt gggcatggtc tcagccagat
    15661 cggggtccac gatggccacg tccggggtga tctcaaagtc cgcgatgggg tacttgatgc
    15721 ccttctggta gtcggtgatg atggagaagg cggtcacctc ggtagcagtg ccggaggtgg
    15781 aggaaatggc gcagaagtgt gccttgcggc gcagcggcgg gatgccgaac accttgcaca
    15841 tctcctcaaa ggtgatctcg gggtattcgt acttgatcca catggccttg gctgcatcga
    15901 tgggagagcc gccgcccatg gcaatgatcc agtcgggctc aaacttcagc atggcctcgg
    15961 caccgcgcat gactgtctcc acggaaggat cgggttcgat gccctcgaac agctccactt
    16021 ccatgccggc ttccttcagg tactccacgg cacgatccag gaagccgaaa cgcttcatgg
    16081 agccgccgcc gacacagatc attgcctttt ttccggtgaa ggacttcagc gcttccagag
    16141 cgcccttgcc atggtacaga tcacggggca gagtaaaacg agccataata caaaacctcc
    16201 aaaaatagta cggcacacgc agcgctgtac cgcagttcat cattatgtta attatataac
    16261 aatttggaga tggcttcaat tgacgtaccg ggagaaaaag tcgttctatt ttgggcggtt
    16321 tccacaagca gtaggatgca acaagccccc tgccctgaaa aaagcgcaaa aaaacacccc
    16381 gaagtcctaa gacttcgagg tgcttgcctt tggagctgct atccagattc gaactggaga
    16441 cctcatcctt accaaggatg cgctctacca actgagctat agcagcaaat ggcgacccgg
    16501 atcgggctcg aaccgacgac ccccagcgtg acaggctggt gctctaacca actgagctac
    16561 cgggccatga tcgctcaagt tcgtgcggca tcttaccgcg ggaacgtact ctattatatc
    16621 ggaaagtcgg tctgttgtca agcacaaatt tgcggaaaat gcaatttttt gcaaaagcgg
    16681 gtaaaggtgg gctgtttggg acgctgagac gattttaaat ggcttccgct tcgctctagc
    16741 catcttcagc ggaaaaaata ttttaaattt cgcgtttgtc gcgctctgcg gagcgctcca
    16801 aacgctattt tcacgggagg ggtcatagag tgaaacggca gagggagtaa aaacaaaacg
    16861 cacaagttcc gaagaacctg tgcgtcatgg caggggtagt aagtttcgaa ctcacggcac
    16921 gcggttttgg agaccgctgc tctaccagct gagctatacc cctatataca ttcgctgaat
    16981 gcttgattat tatagccgat gcaacgggga atgtcaagcc ttatttttac ttattctcat
    17041 ttttcgcgcc gccgcagctg cagcagctct cctgcgcggc ggaatccggc gcaggcagct
    17101 ggcttgccag ctgttccagc gtaacgctgt cgatatactg gttgatcacc tcgtccagcc
    17161 ccgcccagaa cggcagggtg aagcactgct cggacatggg gcattcgttg gtcacgctgc
    17221 caaggcacgg aatgggcgct acgctgccct cgatggcgcg caggatctcg ccggcggtgt
    17281 agtcggcggg gtctttcgtc agccggtagc cgccctgact gccccgctcg ctcttgacca
    17341 gccccacccg cgccagcggg gtgacgatct gttccagata tttcaggctc aggttctgcc
    17401 gctcactgat ctccttcagg ctgacggtgg tgcccggcgc atagcgcgcc agctccgcca
    17461 tcaggcgcag ggcgtagcgg ctcttggtgg aaaatttcat ggtagtcctc tccttgttgc
    17521 agtttatagt atagcacgtt actcggattt tgcaaaggag aaacctcttg tgcaaacaaa
    17581 aaaggtctgt tatcatagga tggaacagaa cctatctttg aggagtgaga gtatgacaga
    17641 aaagatcacc gccgcagacg ccatccgtct gctggatacc ggcaaggctg tcgcagtgga
    17701 tgtgcgcgag ccggacgaat acgccgtagg gcacatcccg ggggcaaagc tgctgccgct
    17761 ggggcaggtc atcgaccgcg ccgccgaggt gctgccggac aaaaacgccc tgtggctggt
    17821 gtactgccgc accggacgcc gcagcgccga cgctgtgcag aagctggaag cccttggcta
    17881 cacccacctg cgggaccttg gcggcatttt aagctggccc tacgagatcg agggcgattt
    17941 tgaggggcat ttttaaggtt atatacttta taagaagcac aaacccatac cagaaaggaa
    18001 accatgccat gtcgttccat gcaaaagagt tcgcgggcag ccactgcggc tgccgttacc
    18061 agcaggatta ccgccctact ttagggcggg acggcaaaaa ggaatccggc acgctggagg
    18121 tcatcaagtt ctactacgat ggcgccatcc gctttgagca gcactgctac ggcgaggctg
    18181 ccacctttgt gttcggcgta tgggcgtccg gcatggatga ggacggcacg ctgaactggg
    18241 tactgccgga ccgccgcaag agctattacg acgaaagcta tctgcccaaa aagctggacc
    18301 gggtggacga agccggaaac ctgtactttg acggcggcat cttcccgtgg aagctggcgg
    18361 acgactttgc cgaggataag cgctggggct accccaagtg gaaggtggcg ctgggtaagc
    18421 tgaccggaaa gggcaaaaaa ggtgactgaa tcacgaaaat ccagtattca tattgacata
    18481 ctagggaatg atatggtata acttatccgt tgaaaggatt ccgcatctgc acagggcatt
    18541 caaggctccc gcagacgcgt tcaataagaa aggatcattc ctatggaaaa catggaaaaa
    18601 gtggtttatc tggataatgc tgccaccact ccctgtgctc ccgaggcact ggaaatgatg
    18661 gtcaaagccc tgagcggtgc ctgcggcaac cccagcagcc attacagcat cggctatgag
    18721 gcaaaggaat tcgtggacac cggccgtgcg caggtggcaa aggccatcaa tgcaagtccg
    18781 gctgagctct tctttaccag ctgcggctcc gaggccgaca actgggcggt aaagggcacc
    18841 gcctttacca aggcacgcca gaacaaaaag cacctcatca ccagcgcttt tgagcatcat
    18901 gccatcatgc acagcatggc tgcactggag cgcatgggct ttgaggtgac ctatatccgt
    18961 cccacctccg agggctacat ccgccccgag gacgtggagg ctgccatccg tcccgacacc
    19021 gcactggtca gcatcatgat ggccaacaac gagatcggca ccatccagcc catcaaggag
    19081 atcgccgagg tcgctcacaa gcacggtgtc tggatgcaca ccgatgcggt gcaggctgtg
    19141 ggtgccatcc ccgtggatgt gaaggagctg ggcgtggata tgctgtccat gagcgcccac
    19201 aagttcaatg gccccaaggg catgggtgca ctgtactgcc gtaagggcgt atggccccag
    19261 aacttgatcg atggtggcag tcaggaggcc cgccaccgtg caggcaccga gaacgtggcc
    19321 ggcattgctg ccatgggcaa ggcactggag atcgccacgg cgcatctgga tgagcgcatg
    19381 gcccacgaga gcgagctgcg cgattacgtc atcgaccgca tcctcaagaa catcccggaa
    19441 gcccgcctga acggcggccg cagcccccgt ctgcccaaca atgtgaacat cagcttcccg
    19501 ggtctggagg gcgagaccat tctgctggat ctggatatgc acggcatctg cgcctctacc
    19561 ggctctgcct gcaactccga cagtctggac cccagccatg tgctgctgag catcggcctg
    19621 ccggaggaga tcggccacgg ttccatgcgg ttcacctttg gcccgcagaa caccatggaa
    19681 gaagcaaaat atctgtgtga cgtgctggag gaggtcattc cccgccgccg cgctatgagt
    19741 tgtatgtggc tgcagggtca gaacaaggcc cgccagttca gcctgaaggg agaacagtaa
    19801 ttatggcaag tatgtatagt gccaaggtca tggagcattt cgcaaatccg cacaacgtag
    19861 gtgagctgcc cgatgcaaac ggcgtgggtg aagtgggcaa tcccaagtgc ggcgacatca
    19921 tgcgcatgta cctgaagatt gagaacaatg tgatcgtgga cgtcaagttc ctcacctttg
    19981 gctgcggcgc agctattgcc accagcagca tggccaccga cctgatcaag ggcaagaccg
    20041 tggacgaggc gctgaagctg accaacaagg ccgttgtgga ggctctggag ggtctgcccc
    20101 cggtcaaggt gcactgctct gttctggccg agcaggccgt caaggctgct ctgtccgact
    20161 actaccgccg tcagggcatc gacccggagc ccatcgtggg caaactggaa gaggactgtg
    20221 agcactgcga gagctgcggc aactgatcct gacagtatca taagcaaaaa agaggacacc
    20281 gcttcgtgcg gtgtcctttt ttgcgtcccc acttgtgaga aaaggggttc agaaacgccc
    20341 gcaggcgttt ctgaacccca aaaaatcaaa tcgttttcct cgccttacac cccgccgtgg
    20401 cggcgctgct cggcggcaag ttcctgctgc aaagcggcct tgcggtgatc cagcagcaga
    20461 tccttgttgt acttgaagta ccgttcgcag ccgttctcgg tgaggaactg gtgggaggcg
    20521 gggttcaccg taagttcggt gacgaacacc accatctcct gactttccgc aaaggcctgc
    20581 tccataaagt cgaaggcggc ttccagcgca gcggcggcgg tcttttgggc ggcttcgcgc
    20641 tggtctgcca gtgcgccgaa ctgaccgcgc agcaggtcga aggcctcctg tgtaccggcg
    20701 gcgttggcgc ggcgcagctc cccttcccac tggtgcagcg cggcctgcac ctgcagacgg
    20761 ttggtcagtt ctgccttgcc cagcagcccg gcatcgcgct tttgctgggt ctcggcttcg
    20821 tagtccttga tctgctggct gaacagctct gcggagccgt ccgggatatc ctccggcagg
    20881 gcagccagcg cctttttggt ctcccgcaaa aaggcgtagc aggcatcggc cacggcatcc
    20941 gcctgcaaag aggcggtaaa acgggtgtcc agcccggcca gcagcagact gacaaggcta
    21001 agccgctcgt caaagggagc ctgcagcagc cgtgcgaaca cggcgggctt tgcctgcccg
    21061 gcaagaattt cctccacgcc gtagtcgtcc cggtacttgt agtacagatc cagataggcc
    21121 gagaagtcct cggcgatctt cgggtgctgg atatactccc ggatcagttc ctcgtccgcc
    21181 tgcaagccca gtgcttcgta ggtgtccagc aggttggaaa gatcctccca gccgcgggcg
    21241 gtgacgaact gggtgccgtc cacgtccgcg ttgatctggt agaagttctg gggatgcagt
    21301 tccagataac tcaggatggc actgtggata tgcgcagcac gggcgtagtc cttccacacc
    21361 ggcaggtcgg gctcgatatc catgcggcgc acgcggtcaa gggttacgat gtcaaaatcc
    21421 cggacggatt tattgtattc cggtgggttg cctgccgcca cgatgaccca gcccgcaggc
    21481 acggcctgat tgccaaaggt cttgcactgc aaaaattgca acatggtggg ggccaacgtc
    21541 tcggacacgc agttgatctc gtcgatgaac agaatgccct ccgaaaggcc ggtggcctcc
    21601 attttagcgt agatgctggc aatgatctcg ctcatggtgt attcggtcac cgatacgtcc
    21661 ttatcgccgt agtggcgctg ccggataaag ggcagaccca cggcgctctg gcgggtgtgg
    21721 tgggtgatgg tgtaggccac cagtgccacc ccgcactccc gggccacctg ctccatcacc
    21781 tgcgttttgc caatacccgg agggcccatc agcaggatgg ggcgctgccg gatggcggga
    21841 atggcgtatt cgcccagcgc atccttggca aggtaagctt ttacggtatg ctcgatttct
    21901 tctttggcac gtttgatatt cataatggtt ccccctcttg tcaggagttg ttcagctcgc
    21961 ggtacaggtc gtcctcctcg gccagagcgt ccgcaagggc gctggccggg cgggctgccg
    22021 caccggtaaa ttcttcttcg tccagtacca ccttcatcgc ccacggcggc acattggcat
    22081 catcgaaccg ctcccccaaa aacagaaagg cggtatcgta gccgggacgc cgcgccgggt
    22141 aggtgcccat gccgtcggtg aagtacagca ggccgcgcag gttcgaaaac ttcttttcgg
    22201 cgcaaagctg atccacatat gcaaaggccg ggcggaaatc cgttccgccg ccgccccgca
    22261 gctcaaagtg gttcatggcg tggatgagct cgtcctcgtt gcggatgagg atatcctgcc
    22321 gcacggcgtt gtcggcctga atgaggtgca gattcatgcg gtggaaaaag ttttcccgcc
    22381 ctttcagcag ggtgtaggtc tcggccagaa aggcgcgcac cagctcgccg gaggtagagt
    22441 agctggtatc aatgaccaat gccagctcct cgatcttttt gctttcccgg ctttccagcg
    22501 gctcgatcag gggcaggttg ccgtacaccg aaaggccgta ggtgtagaag ttcagatcga
    22561 actcgtccgg gtccagtttt acctcctcgc gcaggacgca gaaccggcgc agaaagtcct
    22621 tgtagctgcg gcggctgcgg ttggcggcct tcacctgctg cttcaaggca tcggtgccct
    22681 cgcccgcctc tttatcccgc agatccagct cggtctgcat ccgctccccg atcttctgcc
    22741 acgttttctg cggcagaggg gtgggcatct gctggggctg ctccggggca tccttcggcc
    22801 acaggcggtg gtcgtcggtg acaaattccc gctccagctg ccgcagcacg ccgggcgtct
    22861 gccgggtgag ccaacggtac accggcgctg ccgccaccac cttttcctca gcggtgatct
    22921 gccggtaggc attctgccgc acataggtga gcggacgcat cacgcttttg cgctgtaagc
    22981 tgtcaatgac gt
//
