LOCUS       c00022_gnlPro..        24861 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PJOAFDGM_24.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 18:57:49
            Original ID  :: gnl|Prokka|PJOAFDGM_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 45090
            Orig. end    :: 69951
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24861
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[55090:59951]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14861
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..24861
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24861
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="1"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             complement(401..1663)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_42"
                     /sec_met_domain="Aldedh (E-value: 6.7e-11, bitscore: 35.2,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQEILEAARGAKAALALADSASRAQALCSMAAQLCSPANMTAI
                     LAANADDMAAAKGHISEVMLDRLALTEERIRAMAKGIEEVAALPDPVGRVLKRVERPNG
                     LVIEKTAVPMGVIAIIYESRPNVTSDAAALAIKSGNACILRCGKEAWRSANAIVQALRQ
                     GLRENSLPENAVCLIEDTTHASANALMTAVGYVDLLIPRGGAGLIRACVENAKVPCIQT
                     GTGICHIFVDNTADQAKALDIIENAKASRPSVCNAEEVCLVHSAIAQEFLPKLAQRLGP
                     DRVAAGKLPVELRLDARAAAIIPGMPAGPADFDTEFLDYILAVKVVDSVDEAIAHIAQH
                     STGHSEAILTQTQADADRFTAAVDSAAVYVNCSTRFTDGGEFGLGCEMGISTQKLHARG
                     PMGLEELCSYKYVIHGDGQIR"
     CDS             complement(1667..2464)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_43"
                     /sec_met_domain="AA_kinase (E-value: 1e-43, bitscore:
                     143.6, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIVVKVGTSTLAYPTGRLNIRHAEELVKVLSDLKNEGHEVILVS
                     SGAIGMGVGKLSLPARPKDTTTKQACAAVGQCELMYTYDRLFSAYDHTVAQILLTGVDV
                     EHTERRVNIQNTLTRLLELGALPIINENDSVATDEITSIGDNDTLAAIVACCCKADLLV
                     LLSDIDGLYTANPHTHPDAALIPLVEEITPEVMALADGAGSALGTGGMATKLRAARMVT
                     GSGADMVIANGAHPELLYDIAAGKPIGTRFAGHKQPALSTQEV"
     CDS             complement(2472..3278)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) P5CR_dimer"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046:NADP oxidoreductase coenzyme F420-dependent
                     (Score: 64.4; E-value: 3.8e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_44"
                     /sec_met_domain="F420_oxidored (E-value: 1.5e-19, bitscore:
                     64.4, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="P5CR_dimer (E-value: 2.2e-41, bitscore:
                     134.4, seeds: 951, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKTIGFLGCGNMGGAIARAVCKATEPENVFLANRTAAKAEALAA
                     ELGCQTATNAEVAGNCDLIFLAVKPQMMEAMLEPLRFILAERTKRFVLCTMAAGLPVAR
                     IQEMAGGDYPVIRIMPNTPASVGEGMIQYCSANVTAEEEAAFCRLMAPAGRLDAVAEGM
                     IDAASCVSGCGPAWVYQFIEALADGGVACGLPRAKAQEYAAQMVLGSAKLVLESGKHPG
                     ALKDAVCSPGGSTIQGVRVLEEHGLRGAVMDAVLAAYDKTKEMGKG"
     CDS             3549..4124
                     /locus_tag="ctg22_45"
                     /transl_table=11
                     /translation="VSQTTKRALEASFKKLLLEKPLNKITINDITEDCGVNRMTFYYHF
                     KDIYDLVDWILAEDAAKAMEGRRGFGTWSEAYLDVLRQLQDNKTLVLNVYRSVGREQVE
                     QYLYRLLDPILKDFADRECHDITVQDADKQFVVDFYKYALVGMTLEWTRRDMKGDPKKM
                     VERVSTMIHGDFRRALCRLSSGSLKIEE"
     CDS             4293..5723
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_46"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-17, bitscore:
                     57.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSLDNLTHKMQRAALGKIVDVALSRAEQDREKTMNQLVDAAKQ
                     FYGSGFSDETYENAKKVLTDPDSKWTKLINCVLDQTDPHVARTTALNLGYEAFFRGTKM
                     IRENRVKYQCNIPWLILFDPTSACNMHCVGCWAGEYGHKNNLSFEDMDKIVTQGKELGV
                     YLYMLTGGEPLVRKMDVLKLAEKHNDVQFAIYTNSTLIDEPFCEEVQRLGNIAFMLSIE
                     GTPETNDARRGEGHYAAVMHAMDLLKKYGIIFGTSICYTRQNIEAVTNDAFMRLLCEKG
                     AHFGFYFHYMPVGNEAAPELMPTPEQRKYMIDRIRYLRSSACDIPFYPMDFQNDGEFVG
                     GCIAGGRNYFHINSAGDAEPCVFIHYSNANIHDQSILEILHSPLFRAYHNGQPFNKNHL
                     RPCPMLENPELLEKMVHETGAHNTDLQSPESVEHLCEKCKSYAANWQPTADEVWSHHKV
                     RESRYENYKDWKPSHPLD"
     CDS             complement(6012..6167)
                     /locus_tag="ctg22_47"
                     /transl_table=11
                     /translation="MGIKMMLLGIAVILAGIALSISNIFAFVGGAAGLLITIAGMLVRG
                     KNTTEK"
     CDS             complement(6259..7518)
                     /locus_tag="ctg22_48"
                     /transl_table=11
                     /translation="MDKKPHIKPYLYGMLAGFGAIALSIIFFFLIYRFDGFGSAISTLT
                     GILMPFIYGAVIAYLLKPVCNSIENFLRRFIPEKMNGLINALSVALTILFGLLLVYALV
                     MMIVPQLITSVTTLYYTAQANITKFMNWANHLEFIEKNEQITELLNSAYAALNTNLDTW
                     NTWLKNTLLPSMQNIVSGAAIGVLNVVTVAKNLIIGIIVAVYMLASRKRFVQQGKLVLH
                     SIVRPRWAQLITEEVKYADKMFGGFINGKIMDSAIIGVLCYIGCLIFKFPSALLVSVII
                     GVTNVIPFFGPFIGAIPATLLILIQSPIKALWFVLFVLVLQQLDGNIIGPKILGNTTGL
                     SSFWVLFAILLFGGLWGFVGMIVGVPLFAVIYDVIKKLVIHGLQRHQELTLLNSYHDQF
                     GDPADDAAAQPTAPQSAENQ"
     CDS             complement(7570..8916)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AcetylCoA_hyd_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AcetylCoA_hydro"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_49"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 1.9e-60,
                     bitscore: 197.2, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 2.2e-26,
                     bitscore: 87.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKELYAQKLMTAAQAAALVKSGDWVDYGWAVNTPVAVDAELAK
                     RLPELEGVNFRGGILMWVPEIFQIDDPAAHMTWNSWHMGGIERKAIAQGFSFYSPIRYS
                     ELPRYYRESSDPVDVAVFQVTPMDEHGYFNFGPSASHLGAVCEKAKKIIVEVNTNMPRC
                     LGGMENSVHVSQVSGIVEGTNPPIGQMAAAGAATEVDLKVANLIVPQIPNGACLQLGIG
                     GMPNAIGGLIAQSDLKDLGVHTEMYVDAFVDIAKAGKINGSRKQLDKGRQVYAFGAGTQ
                     KMYDYLNDNPECMSAPVDYTNDIRSISALDNFISINNAVDIDLFGQVNAESAGVKHISG
                     AGGQLDFVLGAYLSKGGKSFICLSSTFFNKKTGQLESRIRPTLENGSIVTDTRANVHYL
                     CTEYGCVNLKGLTSWEKAEALISVAHPDFREELIREAEKLHIWRRSNKI"
     CDS             9419..9919
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_50"
                     /sec_met_domain="CTP_transf_like (E-value: 6.1e-25,
                     bitscore: 82.0, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATAVYPGSFDPVTKGHLDIIKRAAKINDHLIVAVLINSAKHPLF
                     TVEERVAMLQECCKNIPNVTVESFDGLTVEFAKKRHASVMVRGLRAVTDFENEIQLAQT
                     NHALMPGIETMFLATSIKWSYLSSTIVKEAAYYGSDISKFVTPNVEKAVSEKYAQLRER
                     KEI"
     CDS             10001..11218
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_51"
                     /sec_met_domain="Thiolase_N (E-value: 9.2e-92, bitscore:
                     301.0, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 1.1e-47, bitscore:
                     154.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIVIASACRTAIGKFGGTLANVPAAELGSIVIKEALNRANVKP
                     EQVDHVYMGCVIQAGLGQNVARQAALKAGLPIETPAVTVNVVCGSGLNCVNMAAQMIEA
                     GDADIVVAGGMENMDMAPFALQKARYGYRMGAPMGKSEIVDTMVNDALWDACGFNKHMG
                     MTAENVCTNETYQKKYGYSPITREMLDEFSYNSQLKADKAIKDGAFKDEIVPVVIKGKK
                     GDTVFDTDEGPRLSAPEVLAKLKPAFTKDGIVTAGNSSAINDGAAALVVMSEEKAKELG
                     VKPLATWVAGALAGVEPEVMGLGPIAATKKVMAKTGMTVADMDLVEANEAFAAQSIAVG
                     EALGFDKDKLNVNGGAIALGHPVGASGARILVTLLYAMKHRGAHKGLATLCIGGGMGCA
                     TIVEMD"
     CDS             11343..12128
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_52"
                     /sec_met_domain="EC1_2-faecali (E-value: 3.1e-92, bitscore:
                     302.3, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFVKTEVQGAVEIITIDRPKALNALNPEVLADLKAAFEAVDQET
                     VRCIVLTGEGDKSFVAGADIGSMSTMTKAEGEAFGKLGNDVFLMIEHFPIPVIAAVNGF
                     ALGGGNELAMSCDIRICSDNAVFGQPEVGLGITPGFGGTQRLARLVGMGMAKQLVYSAL
                     NIKADEAYRIGLVNAVYPQAELMENVLKLAGKIAKNAPIAVRNCKKAMNDGISLPIEKA
                     VEVEEKLFGACFETHDQQEGMACFLSREKPKPKAVFTNN"
     CDS             12168..13040
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_53"
                     /sec_met_domain="HCDH (E-value: 1.9e-33, bitscore: 109.0,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 2.8e-60, bitscore: 197.2,
                     seeds: 60, tool: rule-based-clusters)"
                     /sec_met_domain="F420_oxidored (E-value: 1.2e-06, bitscore:
                     23.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGVIGAGTMGQGIAKAFAQVEGNTVALCDIKQEWAENGLAKIK
                     KGYEKLVAKGKMTQEKADAIVAAITPGLKEDLCADCDLVVEAAFEDMKVKQTTFGELDK
                     ICKPECVFASNTSSLSITEIGKGLSRPLIGMHFFNPADRMKLIEVIAGCNTPAETVEKI
                     KEIAVAIGKSPVQVNEAAGFVVNRILIPMINEAAFIKMEGVSDIAGIDTAMKLGANHPM
                     GPLELGDFIGLDICLAIMDVLYNETGDSKYRACPLIRKMVRGGNLGCKTGKGFYVYNAD
                     RTKTPVDQL"
     CDS             13147..14316
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_54"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.4e-49, bitscore:
                     159.8, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 9.1e-29, bitscore:
                     93.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.6e-39, bitscore:
                     128.4, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLSKQQQMVQKMYREFAENEVKPLAKKVDAEEYFPKETVEKM
                     GKLGMMGIYFPTEVGGAGGDVLSYVMAVEELSKVCGTTGVIVSAHTSLCAAPIYENGTP
                     EQKAKYLPKLCSGEWLGAFGLTEPGAGTDAQGQQTIAKEDGDYWVLNGSKIFITNAGFA
                     DVFIVIAVTDNVLDKRGRPTKLCSAFIVERTDPGFSVGKAEDKMGIRGSSTCELIFEDC
                     RIPKDRMLGVRGKGFQLAMATLDGGRIGIASQALGIAEGALEETIAYVKERKQFGRAIA
                     AFQNTQFELAEMKARVEAAKYLVYAAALKKQQAMDGAKVRYSVEAAQAKLIAARTASDV
                     TRRCLQLFGGYGYTRDYPIERMMRDAKITEIYEGTSEVQMMVISGALLK"
     CDS             14334..14861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_55"
                     /sec_met_domain="ETF_alpha (E-value: 3.7e-35, bitscore:
                     113.8, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIVCVKQVPDTSGKVSVKPAFSLTAEDIKTEVLSVEKAAEKLV
                     DLIGADVIVSVGRGISKDVNKGIELAEQLAAALGGGVVGASRAVTDAGWMTADHQVGQT
                     GKTVHPKIYVALGISGAIQHTAGMQDSECIIAVNKNEGAPIFGVADYGIVGDLFKVVPE
                     LIKQIEAAKAAL"
     CDS             15409..16347
                     /locus_tag="ctg22_56"
                     /transl_table=11
                     /translation="MKRAMSTVKNIAAAAMTLAVFFGFAGFKPVTANAAQAAMPATASV
                     EEENSYFEEDAYQRSFLTLINNERAQAGLAPVALGDSNHNAAAMERAEELAVSYSYVRP
                     NGQRDFTVLAENGISDVSIGENYMAGCSTPDSAMDQWMATDFTRERILNADATTVSVGY
                     YEGGVYNNYWVLIFSYPENSHTEDYRQEVLNLVNAQRAKYGLTALKMGDDALTAAAQTR
                     AEEIAVVNSHVRPDGSKCFTVLKDYGVTDTPTGENAAWGSVSPEEVVNAWMNSEGHRAN
                     ILNPEARKMSVGYYYNSNSTWGHQWIQIFTK"
     CDS             16461..17081
                     /locus_tag="ctg22_57"
                     /transl_table=11
                     /translation="VEDYRTVRGTATGEYEEKKSRFIAQLSFADSEEAAVAFLEQVRAA
                     NRTARHNVYAYRLRAGNRERYSDDGEPAKTAGTPALEVLQHSGLTDLIVVVTRYFGGVL
                     LGTGGLVRAYTTATARALENAEVVTVRSVVELQVTVDYALYERASLLIDAAGAKQAPPE
                     FTDRVTLRWQMPEHTEAPLLEQLRELTRGSAQVTVSDPFYAPF"
     CDS             17224..18222
                     /locus_tag="ctg22_58"
                     /transl_table=11
                     /translation="MDVRRRTEEIEHLTFAPWATFSDASRGRVVPEPQDPLRPVFQRDR
                     DRVLHCKAFRRLKQKTQVFLSPEGDLYRTRLTHTLEVSQIARTIARGLRLNEDLTEAIS
                     LAHDLGHTPFGHAGEKALNDLCPDGFHHYMQSLRVVDRLEKDGEGLNLTWEVRNGIVTH
                     TKGTWAATPEGRIVRLADQIAFVNHDIEDAVRAGVLDAATLPKDCTAVLGQTKSARITT
                     MINSILTHSEEDVRMGTEEYEAFLALRDFMYATVYVDKNAKREEQKVDKLIAELYEYYL
                     THVDQMSNFYVQLAYQEGRERAVTDYISGMSDEFAIRTFEELFVPQKWHVL"
     CDS             18248..20023
                     /locus_tag="ctg22_59"
                     /transl_table=11
                     /translation="MIPHEYIEELTRRTDIVELVGSYVQLKRKGRLYGGLCPFHSEKTP
                     SFYVYPDTQSFYCFGCQAAGDAISFVKKINNISSGEAIKMLASRAGMPEPQEDDKTGRL
                     RSRVLSMNKEAARFFHACLNSTVEEARQARAYWRRRGLDDKTIVRFGLGYAPNDGQALY
                     QYLRDKGYNQQELDASGLFKRSQSGRIYCLFWKRVMTPIFDLRGNIIAFGGRVMDDSKP
                     KYVNSPETLVYHKSETVFAMQIAKRSASRRFVLCEGYMDVISMQQAGIDTAVCACGTAL
                     TPGQVRIISEYADEVILSYDSDEAGQKATLRSLELFRNSPVKVGVLQIPGAKDPDEYIK
                     KYGPERFQALLDGVGNALDFRLKRLRDQYDLSQDAQRLQYVKEAVEMLAERSNPTEQEV
                     YAGRLAEETNISKTAILAQLGTAVKRAGGKYRREKNRELLRSGEMDQIKVPYSAGGSQA
                     LGIASAQQRLLAAILREPRYLELAKQQLTAEQFIQPQQKELYEAMLNCSREGVELSLTA
                     LRAFVSEEALNELSRLAAQYSDVNCTPDDIRLYLDRIARGMPVASKAAAMSGDEITQYL
                     QSMREKKQGTLPEQD"
     CDS             20072..21154
                     /locus_tag="ctg22_60"
                     /transl_table=11
                     /translation="MQKLSQTEELARSLAAKAHRHTLTTEQISRAMEEADFDIAQLDEL
                     YAALEQRGVHLAEEEPAELPVLDDAQIGRLENELSSEGVALDDPVKTYLKEIGRVPLLT
                     AGQEMALAKAARAGDADARRALSEANLRLVVSVAKRYAGRGLPFLDLIQEGNLGLMKAA
                     EKFEPERGFKFSTYATWWIRQSITRAIADQGRTIRIPVHLVESINRVKKTAGDLLHKNG
                     REPTVEEIAAALDMEPDKVRELLQLSQEPISLETPVGEEEDAHLEDFIQDEDAGVPVDE
                     AGRQLLRRELLHVLKSLTPREERVITLRFGLEDGRARTLEELGKEFNVTRERVRQIEAK
                     ALRKLRHPSRAKLLRDYLDE"
ORIGIN
        1 tgtgatgtac gaatttttga agttctgtga aacgagagtg aaatcgatat caaatcttac
       61 actataattt taccgcacaa aaaaagctct gtcaagagaa aattttgctt ttttgaccta
      121 taaaaacata aaagtactac ttttacattg tgagaaacgg cgaattcttg gatacatacc
      181 gctatccaag aacgctcgtt ttatgggaaa ggtgaaaaat ttttcagttt tcatattcat
      241 tttaaaatac agtccatccc ggtaaaacaa aaatacaggt cgaagcagct tgcatcggcc
      301 tgtacaggaa atttttttca actgtgaaaa acttgctctg ccgcgcccgc aggccggaca
      361 gaattgtaaa aaaattatga agaagccggg gcaggggaga tcagcgaatc tgcccgtcac
      421 cgtggataac gtacttgtag ctgcaaagct cctccagccc catgggtccc cgggcgtgca
      481 gcttctgggt agagatgccc atctcgcagc ccagaccaaa ctcgccgccg tcggtaaagc
      541 gggtggagca gttcacatac acagcggcgc tgtctaccgc agcggtgaac cggtcggcgt
      601 ctgcctgcgt ctgggtcagg atggcctcgc tatggccggt ggagtgctgc gcaatgtggg
      661 caatggcctc atctacactg tccaccacct tgacggcaag gatgtagtcc aaaaactcgg
      721 tgtcaaagtc cgcagggccg gcaggcatgc cgggaatgat ggcggcggcg cgtgcgtcca
      781 gccgcagttc taccggcagc ttgcccgcag ccacgcggtc ggggccaaga cgctgtgcaa
      841 gcttgggcag aaactcctgc gcaatggcag agtgcactag acacacctcc tcggcgttgc
      901 acacgctggg gcggctggcc ttggcgtttt caataatgtc cagcgccttg gcctgatcag
      961 cggtgttgtc cacaaaaatg tggcagatgc cggtaccggt ctggatgcag ggtaccttgg
     1021 cgttctccac gcaggcgcgg atcagccctg caccgccccg ggggatcagc agatccacat
     1081 agcccacggc ggtcatcagg gcgttggcag aggcgtgggt ggtgtcctcg atcaggcaga
     1141 ccgcgttttc cggcaggctg ttctcccgca gtccctgccg cagcgcctgt acaatggcgt
     1201 tggcgctgcg ccatgcctcc ttgccgcagc gcaagatgca ggcgttgccg ctcttgatgg
     1261 caagggcagc ggcatcgctg gtcacgttgg gacggctctc gtagatgata gcaatcacac
     1321 ccatgggcac ggcggtcttt tcgatcacca gcccgttggg gcgctccacc cgcttcagca
     1381 cccggcccac cgggtcgggc agggcagcga cctcttcaat gccctttgcc atggcgcgga
     1441 tgcgctcctc ggtcagggca agacgatcca gcatcacctc gctgatgtgt ccctttgcgg
     1501 cggccatatc gtcagcgttg gcggcaagga tagccgtcat gtttgccggg ctgcacagct
     1561 gcgcagccat actgcacagt gcctgtgcgc ggctggcgct atcagccagt gccagcgcag
     1621 cctttgcccc gcgggcggct tccagaattt cctgtgtggt catagctcaa acctcctgtg
     1681 tggacagcgc gggctgcttg tgcccggcaa agcgggtgcc gatgggcttg cccgcagcga
     1741 tatcatacag cagttccggg tgtgcgccgt tggcgatgac catatccgca ccgctgccgg
     1801 tcaccatgcg ggcagcccgc agcttggttg ccatgccgcc ggtgcccagt gcagagcctg
     1861 caccgtctgc cagcgccatc acctccgggg tgatctcctc caccagtggg atgagcgccg
     1921 catccgggtg ggtgtggggg ttggcagtgt acaggccgtc gatgtcgctc agcagcacca
     1981 gcaagtcggc cttgcagcag caggccacaa tagcggccag cgtgtcgttg tcgccaatgg
     2041 aagtgatctc atcggtggca acgctatcat tttcattgat gatgggcagt gcacccagtt
     2101 ccagcagacg ggtcagggta ttctggatgt tcacccggcg ctcggtgtgc tccacgtcca
     2161 cgccggtaag cagaatttgc gctaccgtgt gatcgtaggc actgaacagc cggtcgtagg
     2221 tgtacatcag ctcgcactgt cccacggcag cgcaggcctg cttggtggtg gtatcctttg
     2281 ggcgtgcagg cagcgaaagc ttgcccacgc ccatgccgat agcgccggag gacaccagaa
     2341 tgacctcgtg tccctcgttc tttaaatcgc tcaatacctt gaccagttcc tctgcatggc
     2401 ggatgttcaa ccgcccggtg gggtatgcca atgtggaggt gcccactttc acaacgatgc
     2461 gcatgattcc attaaccctt tcccatttcc tttgttttgt cgtaagcagc cagcacggca
     2521 tccatcaccg caccgcgcag cccatgttct tccagtaccc gcacgccctg aatggtgctg
     2581 ccgccggggc tgcacacagc atccttcagc gcaccggggt gcttgccgct ttccagcacc
     2641 agctttgcgc tgcccagcac catctgtgcg gcgtattcct gtgcctttgc ccggggcaga
     2701 ccgcaggcca cgccgccatc ggccagcgct tcaataaact ggtacaccca tgccgggccg
     2761 cagccggaga cgcagcttgc agcatcgatc atgccctcgg ctacggcgtc cagacgcccg
     2821 gcgggagcca tcagccggca gaatgcagcc tcttcctcgg cggtcacgtt ggcagagcaa
     2881 tactggatca tgccttcgcc taccgatgcc ggggtgttgg gcatgatgcg gatgacaggg
     2941 tagtcgccgc ccgccatctc ctgaatgcgt gccaccggca ggccggcggc catggtgcac
     3001 agcacgaacc gcttggtgcg ctcggcaagg atgaaccgca ggggctccag catggcctcc
     3061 atcatctggg gcttcaccgc cagaaagatc aggtcgcagt tcccggccac ctcggcgttg
     3121 gtggctgtct gacagcccag ctctgcagcc agcgcttcgg ccttggccgc cgtgcggttg
     3181 gccagaaata cattctcagg ctcggtagcc ttgcatacgg cgcgtgcaat agcgccgccc
     3241 atgtttccac agcctaaaaa cccaatggtt ttcatcataa taataaccct ccctcggcag
     3301 gtatgtactg cataaaattc tgcttcttat tcattctaag caaccgctgg gagaaaatca
     3361 agacttttgt cttattttgg gcggatataa tgtaaaaaca gcactttcgg ggcgggcagc
     3421 gcacacacaa acttcataaa aaggtaagaa tctctacttg aaataaggtc gtattttgcg
     3481 gtaaaataaa ctatggggta tcatttacgg aaacggcaga ggagtctgcc gggaaaggat
     3541 gggtttttgt gtcacaaacg acaaaacggg cactggaggc atctttcaag aagctgctgc
     3601 tggaaaagcc cctgaacaag atcacgatca acgatatcac cgaggactgc ggggtaaacc
     3661 gcatgacctt ttattaccat ttcaaggata tttacgatct ggtggactgg atcttagcgg
     3721 aggatgccgc caaggcgatg gaaggccgcc ggggctttgg tacatggagc gaagcctatc
     3781 tggacgttct gcgccaactg caggataaca agacccttgt gctcaacgtt taccgctcgg
     3841 tgggcaggga acaggtggag cagtaccttt ataggctgct ggaccccatc ctgaaggatt
     3901 ttgcggaccg tgaatgccac gatatcaccg tgcaggacgc agataagcag tttgttgtcg
     3961 atttttacaa gtatgcactg gtgggtatga cgctggaatg gacccgccgg gatatgaaag
     4021 gcgaccccaa gaagatggtg gagcgcgtga gcaccatgat ccacggagat ttccgccggg
     4081 cgctgtgccg cctgagcagc ggcagcttga aaatagagga atgatgtgct ttgtggctgt
     4141 gcggcttcaa taaaatttta tcaaaggata cgccgtgatg ggttttccat cacggcgtat
     4201 tttctgttta tggcacaaaa acgcgcaaag tggtaggatg tggtcaagca aaataaggat
     4261 ttccaaagga atcatttcgg gaggaaaaag ttatgaatac atctcttgat aatctgactc
     4321 acaagatgca gcgtgctgcg cttggtaaaa tagtggacgt ggcgctttcc cgcgccgagc
     4381 aagaccgtga aaagacgatg aaccagctgg tagatgctgc aaagcagttc tacggcagcg
     4441 gcttcagcga tgagacctac gagaacgcca aaaaggtgct gaccgacccc gacagcaagt
     4501 ggacgaaact tatcaactgc gtgctggatc agaccgaccc ccatgtggcg cgtaccaccg
     4561 cgctgaatct gggctacgaa gccttcttcc gcggcactaa gatgatccgt gagaaccgtg
     4621 tcaagtacca gtgcaacatc ccctggctga tcttgttcga ccccacctct gcctgcaata
     4681 tgcactgcgt gggctgctgg gcaggcgagt acggccacaa gaacaacctc agctttgagg
     4741 atatggacaa gatcgtcacg cagggcaagg agctgggcgt gtacctgtat atgctgaccg
     4801 gcggcgagcc gctggtgcgc aagatggacg tgctcaagct ggcagaaaag cacaacgatg
     4861 tgcagtttgc catctacacc aactccaccc tcatcgacga gcccttctgt gaagaagtgc
     4921 agcgtctggg caatatcgcc tttatgctgt ccatcgaggg taccccggag accaacgatg
     4981 cccgccgcgg cgaaggccac tatgccgctg tgatgcacgc catggatctg ctcaagaagt
     5041 acggcattat cttcggcacc tccatctgct acacccgcca gaacatcgag gccgtcacca
     5101 acgatgcgtt catgcggctc ctgtgcgaga agggggcaca cttcggcttc tacttccact
     5161 atatgccggt gggcaatgag gccgccccgg agctgatgcc caccccggaa cagcgcaagt
     5221 atatgattga ccgtatccgc tatctgcgct cttctgcgtg cgatatcccg ttctacccca
     5281 tggacttcca gaacgatggc gagttcgtgg gcggctgcat cgccggtggc cgcaactact
     5341 tccatatcaa ctctgccggt gatgctgagc cctgcgtgtt catccactac tccaacgcca
     5401 atatccacga ccagtctatt ctggaaattc tgcacagccc gctgttcagg gcttaccaca
     5461 acggtcagcc cttcaacaag aaccatctgc gtccctgccc gatgctggaa aaccccgagc
     5521 tgctggaaaa gatggtgcac gagaccggtg cccacaacac cgacctgcag tccccggaaa
     5581 gcgtcgagca cctgtgtgag aagtgcaaga gctacgccgc caactggcag cccaccgctg
     5641 acgaagtgtg gtcccaccac aaggtccgcg agagccggta cgaaaactat aaggactgga
     5701 agccctctca tccgctggac tgagctgaaa tctgaatcaa agcaataaac gacccccgct
     5761 ttgtgttcct tcccggaaca taaggcgggg gtcttgctgt gcatgttggc ggctatttat
     5821 ttcttatcgc tttctttaat tgcctttaga atacaaattc ccatagctaa aacaggaaac
     5881 agcactctga gagctaaaaa accttgtggg tctccaaaat cgatgtttac gtctgcaaat
     5941 agtccaacaa accatgccgc taaagtagaa atgatcgcga ttgtgtaagt catttgtcaa
     6001 accttcgtga attatttctc ggttgtgttt ttgccccgta caagcatacc ggcaattgtg
     6061 attaaaagac ctgcggctcc accaacaaaa gcaaaaatat tacttataga taaggcaatc
     6121 ccagccagaa taacggcgat acccaataac atcattttaa tacccattaa atcgttctcc
     6181 tttatatacg ttcttatgat acggcatggc taaaaaatac cccgcatcgg aagtgctctg
     6241 atgcggggca gggaaggttt actggttctc agcagattgc ggtgcagtgg gctgtgcggc
     6301 tgcatcgtct gcggggtcgc cgaactggtc gtgatagctg ttcagcaggg tcagctcctg
     6361 atggcgctgc aagccgtgga tgaccagctt tttgatgaca tcgtagataa cggcaaacag
     6421 cggcacaccc acgatcatgc ccacgaagcc ccacaggccg ccaaacagca ggatggcgaa
     6481 cagtacccag aagctggaaa ggccggtggt gttgcccaga attttaggtc cgatgatgtt
     6541 gccgtccagc tgctgcaaaa ccagcacgaa cagcacgaac cacagcgcct tgatggggct
     6601 ctggatgagg atgagcagcg tggcgggaat ggcaccgatg aagggaccga agaagggaat
     6661 cacgttggtc acaccaatga tcaccgatac cagcagcgca ctggggaact tgaaaatcag
     6721 gcagccgata tagcacagca cgccgatgat ggcagagtcc atgatcttgc cgttgatgaa
     6781 gccgccgaac attttgtctg cgtacttcac ttcctcagtg atcagctgcg cccagcgggg
     6841 gcggacgatg ctgtgcagca ccagcttgcc ttgctgcacg aaccgcttgc ggctggccag
     6901 catatacacc gccacgatga tgccgatgat caggtttttg gccaccgtca ccacgttcag
     6961 cacaccaatg gctgcaccac ttacgatatt ctgcatggag ggcagcaggg tgttcttgag
     7021 ccatgtgttc catgtgtcca gattggtatt cagggcagcg taagccgaat tgagcagctc
     7081 cgtgatctgt tcgttctttt caataaactc cagatggttt gcccagttca tgaactttgt
     7141 aatgttggcc tgcgcggtgt agtacagggt agtcacgctg gtgatcagct gcggcacgat
     7201 catcatgaca agcgcataca ccagcaaaag cccgaacagg atggtaagcg ccacggacag
     7261 cgcgttgatc agaccgttca tcttttccgg gatgaaccgg cgcagaaagt tttcgatgct
     7321 gttgcacacc ggcttgagca gataggcaat gacggcaccg tagataaagg gcatcaagat
     7381 gccggtcagg gtagagatgg ccgagccgaa gccgtcaaag cggtaaatga ggaaaaagaa
     7441 gatgatgctc agtgcaatgg caccaaaccc tgcgagcatc ccatagagat acggtttgat
     7501 gtgcggcttt ttgtccatca tgacaaactc cattcctgct gcgggcagcg ggaataccca
     7561 cagcgcttat taaattttgt tgcttctgcg ccagatgtgc agtttttcag cctcgcggat
     7621 caactcttca cggaagtccg ggtgtgccac gctgatcaga gcctcggcct tttcccaaga
     7681 ggtcaggccc ttcagattca cgcagccata ctcggtgcac agatagtgca cgttggcgcg
     7741 ggtgtcggta acgatgctgc cgttctccag cgtgggacgg atacggcttt ccagctggcc
     7801 ggtcttttta ttaaagaagg tggaggacag gcagataaag ctcttgccgc ccttggaaag
     7861 gtatgcgccc agcacgaagt ccagctgacc gcctgcgccg gaaatgtgct tcacaccggc
     7921 gctttcggca ttcacctgac caaacaggtc gatatccacg gcattgttga tggaaataaa
     7981 gttgtccagt gcggaaatgc tgcggatgtc gttggtgtag tccaccgggg cagacataca
     8041 ctccgggtta tcgttcaggt aatcgtacat cttctgggtg ccggcaccaa aggcgtagac
     8101 ctgacggccc ttgtccagct gcttgcggct gccgttgatc ttgccggcct tggcaatatc
     8161 cacaaaggca tccacataca tctcggtgtg cacgcccaga tccttcagat cgctctgcgc
     8221 gatcagcccg ccgatggcat tgggcatacc gccgatgccc agttgcaggc aggcaccgtt
     8281 aggaatctgc ggcacgatga ggttggctac cttcaggtca acctcggtag cggcaccggc
     8341 agctgccatc tggccgatgg ggggatttgt gccctccaca atgccactta cctgagaaac
     8401 gtgtacgctg ttctccatgc cgccaaggca gcgcggcata ttggtgttga cctccacaat
     8461 gatcttcttg gccttttcgc acacagcacc cagatgcgaa gcgctgggac cgaagttgaa
     8521 gtagccatgc tcgtccatgg gggtcacctg aaatactgcc acatccacgg ggtcgctgct
     8581 ctcgcggtag tagcggggca gctcagagta gcggatgggg gagtagaagg agaaaccttg
     8641 cgcaatggcc ttgcgctcaa tgccgcccat gtgccagctg ttccaggtca tgtgggcagc
     8701 agggtcgtcg atctggaaga tctccggcac ccacatcaga atgccgcccc ggaagttgac
     8761 tccttccaac tccggcaggc gttttgctag ctcggcgtcc acggccacag gggtgttcac
     8821 ggcccagccg taatccaccc agtcgccgct tttgaccaga gcggcagcct gcgcagcagt
     8881 cataagcttc tgtgcgtaca gttccttgca atccattata aaccatcctc tcttaaaata
     8941 cataaaagaa ttgtaaacaa ttctgtgcgg acaaattatg cggctgtttt acgcctgttt
     9001 tgcggaatgc acaccgtttt gccacatctg tatggtaacc ttataaacaa ggcagcagtg
     9061 tgtgctccgc tctgcgcaga acagctcaac ttagttataa cattaacaaa gtgtagaatc
     9121 aatagttttg gctaaaaaac aaccagtata gcataataaa cagttttctt ggctttatgt
     9181 ggggattgtt tggtacgcaa aaaacaaaaa agttgagaaa aagacttgat aaaattttga
     9241 cgatgtgctt tactaatagc gtgggaagca actgcggagc agtgcgagat gattcgttta
     9301 aaatttaacg ataaaacgca ccgcagcagt ttcaggttgc acccaaggct ggaaagtgct
     9361 atcatggcag aaccacatcg cgcttaataa ttgcagcgca taaggaggac actgaccgat
     9421 ggcaacagca gtttatcccg ggtcgttcga tccggtcacc aagggacacc ttgatatcat
     9481 caaacgcgca gcaaagatca acgaccacct cattgtggcg gtgctgatca acagcgccaa
     9541 gcatccgctg ttcacagtgg aggagcgggt ggctatgctg caggaatgct gcaagaacat
     9601 ccccaatgtg accgtggaaa gcttcgacgg cctgaccgtg gagttcgcaa aaaagcgcca
     9661 cgcatccgta atggtgcggg gactgcgggc agtaacggac tttgaaaacg agatccagct
     9721 tgcgcaaacc aaccacgcac tgatgcccgg catcgagacc atgttccttg ccaccagcat
     9781 caaatggagt tatctttcct ccaccatcgt aaaggaagca gcgtactacg gcagtgacat
     9841 cagcaagttc gtcacaccca atgtggaaaa ggccgtcagc gaaaaatacg cacagctccg
     9901 ggagaggaaa gagatctgat accgcaaaaa tgccgcaggg cgttttgata aatgggtaac
     9961 cgataagtaa cacacataca caattcagga ggctattcac atgaaaaaga tcgttatcgc
    10021 atctgcatgc cgcaccgcca tcggcaagtt cggtggcact ctggccaacg ttcccgctgc
    10081 tgagctgggc tccatcgtca tcaaggaggc tctgaaccgt gcaaacgtca agcccgagca
    10141 ggtcgatcat gtttacatgg gctgcgtcat tcaggctggt ctgggccaga acgtcgctcg
    10201 tcaggctgcc ctgaaggctg gtctgcccat cgagaccccc gccgtcaccg tcaacgtggt
    10261 ctgcggctct ggtctgaact gcgtgaacat ggctgctcag atgatcgagg caggcgatgc
    10321 tgatatcgtt gttgcaggcg gcatggagaa catggatatg gctcccttcg cactgcagaa
    10381 ggctcgctac ggctaccgca tgggcgctcc catgggcaag agcgagatcg tggataccat
    10441 ggtcaacgat gcactgtggg atgcctgcgg cttcaacaag cacatgggca tgaccgctga
    10501 gaacgtctgc accaacgaga cctatcagaa gaagtacggc tacagcccca tcacccgcga
    10561 gatgctggac gagttctcat acaacagcca gctgaaggct gacaaggcca tcaaggacgg
    10621 cgccttcaag gacgagatcg ttcctgttgt catcaagggc aagaagggcg acaccgtgtt
    10681 cgataccgat gagggccccc gtctgagcgc tcccgaggtt ctggcaaagc tgaagcccgc
    10741 cttcaccaaa gacggcatcg tcaccgctgg taactcttcc gccatcaacg acggcgctgc
    10801 tgctctggtc gtcatgagcg aggagaaggc taaggagctg ggcgtgaagc ctctggcaac
    10861 ttgggttgcc ggtgctctgg caggcgttga gcccgaggtc atgggtctgg gccccatcgc
    10921 tgctaccaag aaggtcatgg ccaagaccgg catgaccgtt gctgatatgg atctggtcga
    10981 ggccaacgag gcattcgcag cacagtccat cgctgtcggc gaggctctgg gcttcgataa
    11041 ggacaagctg aacgtcaacg gcggcgcaat cgctttgggt cacccggtcg gcgcttccgg
    11101 cgctcgtatt ctggtcaccc tgctgtacgc tatgaagcac cgtggtgctc acaagggtct
    11161 ggctaccctg tgcatcggcg gcggcatggg ctgcgctacc atcgttgaga tggactaagc
    11221 actctttctc tgaatcctga ctgaaccaca gacccggagc gccggaggga accggagagc
    11281 tctcctgcgt tctgggggct gttttgaaaa aaactgaact gtatgaaatg gaggttttca
    11341 caatggcatt tgtaaaaacc gaggtgcagg gcgctgttga gatcattacc atcgaccgtc
    11401 ccaaggcact gaacgccctg aaccccgagg ttctggctga cctgaaggct gcttttgagg
    11461 cagtcgatca ggagactgtc cgctgcatcg ttctgaccgg cgaaggcgac aagagcttcg
    11521 ttgctggtgc tgatatcggt tctatgagca ccatgactaa ggcagaaggc gaggccttcg
    11581 gcaagctggg caatgatgtg ttcctgatga tcgagcattt ccccatcccc gtcatcgcag
    11641 ccgtcaacgg ctttgcactg ggcggcggca acgagctggc tatgagctgc gatatccgca
    11701 tctgctctga caacgctgtg ttcggtcagc cggaagtcgg tctgggcatc accccgggct
    11761 tcggcggcac ccagcgtctg gctcgtctgg tcggcatggg catggcaaag cagctggtct
    11821 actctgcgct gaacatcaag gctgacgagg cttaccgcat cggtctggtc aacgccgtgt
    11881 atccgcaggc tgagctgatg gagaatgtcc tgaagctggc cggcaagatc gcaaagaacg
    11941 ctcccattgc tgtgcgtaac tgcaagaagg caatgaacga cggcatcagc ctgcccatcg
    12001 agaaggctgt tgaggtcgag gagaagttgt tcggcgcttg cttcgagacc cacgatcagc
    12061 aagagggcat ggcttgcttc ctgtcccgtg agaaaccgaa gcccaaggca gtgttcacca
    12121 acaactaatc cattacataa tttttgatat taaaggagag atttcctatg aagatcggtg
    12181 ttatcggcgc tggcactatg ggtcagggca tcgcaaaggc atttgcacag gttgagggca
    12241 acaccgttgc tctgtgcgac atcaagcagg agtgggccga gaatggtctg gcaaagatca
    12301 agaagggcta cgagaagctg gtcgctaagg gaaagatgac tcaggagaag gctgacgcaa
    12361 tcgtcgccgc catcaccccg ggtctgaagg aagatctgtg cgcagactgc gatctggtcg
    12421 ttgaggctgc tttcgaggat atgaaggtca agcagaccac cttcggcgag ctggataaga
    12481 tctgcaagcc cgagtgcgtt ttcgcttcca acacttcttc tctgtccatt accgagatcg
    12541 gcaagggtct gtcccgtccc ctgatcggta tgcacttctt caaccccgca gaccgtatga
    12601 agctgatcga ggtcatcgcc ggctgcaaca cccccgctga gaccgttgag aagatcaagg
    12661 agatcgccgt tgccatcggc aagagccccg ttcaggtcaa cgaggctgcc ggctttgtgg
    12721 tcaaccgcat cctgatcccc atgatcaacg aggctgcctt cattaagatg gagggcgttt
    12781 ccgatatcgc cggcatcgac accgctatga agctgggtgc taaccacccc atgggacccc
    12841 tggaactggg cgacttcatc ggtctggaca tctgcttggc catcatggac gtgctgtaca
    12901 acgagaccgg cgacagcaag taccgtgcct gcccgctgat ccgcaagatg gtgcgtggcg
    12961 gcaatctggg ctgcaagacc ggtaagggct tctacgttta caacgcagac cgcaccaaga
    13021 cccctgttga ccagctgtaa attctgataa acatttctcc cggctgcggg gaaagcggtc
    13081 gggaggaatt tgtttgcacc gggctattcc ggtaaatgaa aaaagacctg ttaggaggat
    13141 atagcgatgg attttactct gtccaagcag cagcagatgg tgcagaaaat gtaccgcgag
    13201 tttgctgaga acgaagtcaa gcctctggca aagaaggttg acgcagagga atacttcccc
    13261 aaggagaccg tcgaaaagat gggcaagctg ggcatgatgg gcatctattt cccgactgag
    13321 gtcggcggtg caggcggcga tgtgctgtcc tacgtcatgg ccgtggagga gctgagcaag
    13381 gtctgcggca ccaccggtgt catcgtctct gctcacacca gcctgtgcgc tgcccccatt
    13441 tacgagaacg gcacccccga gcagaaggct aagtacctgc cgaagctctg cagcggcgag
    13501 tggctgggtg ctttcggcct gaccgagccg ggcgctggta ccgatgcgca gggtcagcag
    13561 accattgcca aggaagatgg cgattactgg gtgctgaacg gctccaagat cttcatcact
    13621 aacgcaggct ttgctgatgt gttcatcgtc atcgccgtta ccgataacgt gctggataag
    13681 cgcggccgtc ccaccaagct ctgctccgcc ttcatcgtgg agcgcaccga cccgggcttc
    13741 tctgttggta aggcagagga caagatgggt atccgcggtt cttctacctg cgagctgatc
    13801 tttgaggatt gccgtatccc gaaggatcgt atgctgggcg tgcgcggcaa gggcttccag
    13861 ctggctatgg ctacgctgga cggcggccgt atcggcatcg cttctcaggc tctgggcatc
    13921 gccgagggcg ctctggagga gaccattgct tacgtcaagg agcgcaagca gttcggccgt
    13981 gctattgctg ctttccagaa cactcagttc gagctggctg agatgaaggc tcgtgttgag
    14041 gctgctaagt atctggttta tgctgccgct ctgaagaagc agcaggctat ggatggcgca
    14101 aaggttcgtt acagcgtcga ggctgcacag gctaagctga tcgcggcccg caccgcaagc
    14161 gatgtgactc gccgttgcct gcagctgttc ggtggttacg gctacacccg tgactacccc
    14221 atcgagcgca tgatgcgtga tgccaagatc accgagatct acgagggcac cagcgaagtg
    14281 cagatgatgg tcatttccgg cgcgctgctg aagtaaggga ggcaagagtt acaatgaaag
    14341 caattgtttg tgtaaagcag gttcctgata cctccggcaa ggtgtccgtc aagcccgcct
    14401 tcagcctgac cgctgaggac atcaagaccg aagtgctgag cgtggagaag gccgctgaga
    14461 agctggtcga cctgatcggc gcagatgtca ttgtctccgt tggtcgtggt atcagcaagg
    14521 atgtcaacaa gggcatcgag ctggccgagc agctggcagc cgctctgggc ggcggtgtcg
    14581 tgggcgcttc ccgtgccgtc accgatgcag gctggatgac cgctgaccat caggtcggtc
    14641 agaccggcaa gactgtgcac cccaagatct atgtggctct gggtatctct ggtgctatcc
    14701 agcacaccgc cggtatgcag gattctgagt gcatcatcgc cgtcaacaag aacgagggtg
    14761 ctcccatctt cggcgttgct gactacggca tcgtgggcga tctgttcaag gtcgtgcctg
    14821 agctgatcaa gcagatcgag gcagcaaagg ctgctctgtg atcgcctgtt cctgagcatt
    14881 gttcaatagc atagcctgaa ttgtgagagg ccgttgcaca tttttgtgca gcggcctctt
    14941 ttttgtgttt tttataaagg agctgttgtg ccggccactg cacagcagct ccgatttgct
    15001 ccacaggaaa ggaacgcaga agggaacaca gcgaagcgcc acaaaaacgt acacagaaac
    15061 cacgatatgc aaagcggtgc atataaatac agtgatatac aaaacgaaac gcaccgaagc
    15121 gtcccaaaaa gtgtgcggaa actgttgcac ttggcttgtt ttggcgagaa tcgcaacaca
    15181 actgtaacgt tttcggactc tttgttacgc ttgagttgcg ataaaaaggc gagaattttt
    15241 taaaaaatct gtattttttc tgcaaatcaa gctctaaacc tcttgacgtc tgtatggttt
    15301 tgtgatactc ttgttacaca agagttgcgg atgtgatacg acagagttgc aaacgagttg
    15361 caatatccaa gatcacactg cataaggcaa cagaccagag gcaatcttat gaagcgtgca
    15421 atgagtaccg tgaagaatat cgcagcagct gcaatgacgc tggctgtgtt ttttggcttt
    15481 gcaggcttca agcccgtcac cgcaaacgct gcacaggctg ccatgcctgc caccgcttct
    15541 gtggaagaag agaactccta ctttgaggaa gacgcttacc agcgcagctt cctgaccctg
    15601 atcaataacg agcgtgcaca ggctggtctg gctcctgttg ctttgggcga cagcaaccac
    15661 aacgccgctg caatggagcg tgccgaagag ctggcagttt cttactccta cgttcgtccc
    15721 aacggtcagc gcgatttcac cgttctggca gagaacggta tcagcgatgt ctccatcggc
    15781 gagaactaca tggccggctg ctccaccccc gattccgcaa tggatcagtg gatggctacc
    15841 gacttcaccc gcgagcgtat cctgaacgcc gatgctacca ccgtgagcgt tggctactat
    15901 gagggcggtg tttacaataa ctattgggtg ctgatcttct cttaccccga aaattctcac
    15961 accgaggatt accgtcagga agttctgaat ctggtcaatg cccagcgcgc aaagtatggt
    16021 ctgactgctc tgaaaatggg cgatgacgct ttgaccgccg ctgcacagac ccgcgccgag
    16081 gagatcgccg ttgtgaactc ccacgtccgt cccgatggct ctaagtgctt caccgtcctg
    16141 aaggactatg gcgtcaccga tacccccacc ggcgagaatg ccgcatgggg cagcgtctct
    16201 cctgaagaag tcgtcaatgc atggatgaac tccgaaggcc atcgtgccaa tatcctgaac
    16261 cctgaggctc gcaagatgag tgttggttac tactacaaca gcaacagcac ttggggtcat
    16321 cagtggatcc aaatctttac caagtgatta actgctttct tcttataaaa agactggcgg
    16381 ggccgcaagg cttcgtcagt ctttttattt gcgcccgttt gtgttatact tattctgagt
    16441 tattatcagg aggatctaac gtggaggatt accgcaccgt ccggggcacg gccaccggcg
    16501 aatatgaaga gaaaaaaagc cgctttatcg cacagctttc ctttgctgac agtgaggaag
    16561 ctgcggtggc ttttctggag caggtgcggg cggctaaccg caccgcgcgg cacaacgttt
    16621 acgcttaccg cctgcgggcg ggcaaccgcg agcgctattc cgatgacggc gagccggcca
    16681 agaccgccgg tacgcccgcg ctggaagtgt tgcagcacag cggcctgaca gacctgatcg
    16741 tggtggtcac ccgctacttt ggcggggtgc tgctgggcac cggcggcttg gtgcgcgctt
    16801 acactaccgc cactgcccgt gcgctggaaa acgccgaggt ggtcactgtg cgcagcgtgg
    16861 tggaattaca agtgacagtg gactacgccc tttacgagcg tgcatctctg ctcattgacg
    16921 ccgccggggc aaagcaggca ccgccggagt ttacagaccg ggtcaccctg cgctggcaga
    16981 tgccggagca taccgaagcc ccgctgctgg agcagctgcg ggaactgacc cggggcagcg
    17041 ctcaggtaac ggtgtctgac ccgttctacg caccatttta aaaaacaaag tcttttttgc
    17101 aaaccgacac ggaacttccc ccttcgacac ggccgatgtg ctacaattgc cgtagcgcag
    17161 caattgggat cggctgtgcg cagaggggag gggagaagcc cgaaaaacaa aaggaggatc
    17221 tgtatggatg tgcgccggag aaccgaggag atcgaacacc tcacctttgc accgtgggcg
    17281 accttcagcg atgcaagccg cggcagagtc gtgccggagc cgcaggaccc gctgcgcccg
    17341 gtgttccagc gggatcgcga ccgggtgctg cactgcaagg ccttccggcg tctcaagcag
    17401 aaaacgcagg tgttcctctc gccggaaggt gacctgtacc gcacccggtt gacccatacg
    17461 ctggaagttt cgcagatcgc ccgcaccatt gcccggggtc tgcgcctgaa cgaggatctg
    17521 accgaggcca tcagccttgc gcatgatctg gggcacactc cctttggcca cgcaggcgaa
    17581 aaggcactga acgacctttg cccggacggc ttccaccact atatgcaaag cctgcgtgtg
    17641 gtggatcggc tggaaaagga tggcgagggt cttaacctga catgggaggt gcgcaacggc
    17701 atcgttaccc acaccaaggg cacatgggcg gctaccccgg aagggcgcat cgtgcgtctt
    17761 gcggatcaga tcgcctttgt caaccacgat atcgaggacg ccgtgcgcgc cggtgtgctg
    17821 gacgctgcca ccctgcccaa ggactgcacg gcagtgctgg ggcagactaa gtccgcccgc
    17881 atcaccacta tgatcaacag catcctcacc cacagcgagg aagatgtccg catgggcacc
    17941 gaggaatacg aggcttttct cgctttgcgg gatttcatgt acgccaccgt gtatgtggac
    18001 aaaaacgcca agcgcgagga gcagaaggtg gacaagctta tcgcggaact gtacgagtac
    18061 tacctgaccc atgtggatca gatgtccaac ttttatgtgc agctggccta tcaggaggga
    18121 cgggaacgcg ccgtcaccga ctacatcagc ggtatgagcg acgagtttgc catccgcacc
    18181 tttgaagaac tgttcgtgcc ccagaaatgg cacgtccttt aaaactggag aggtcgttta
    18241 aaacaacatg atcccacacg aatacatcga ggagctcacc cgccgcaccg acatcgtgga
    18301 actggtgggc agctatgtgc agctcaagcg caagggacgg ctgtacggcg gtctgtgccc
    18361 ctttcacagc gaaaaaacgc cgtccttcta tgtgtaccct gacacccaaa gcttttactg
    18421 cttcggctgt caggcagccg gagatgccat cagctttgtc aaaaagatca acaatatcag
    18481 cagcggcgaa gctatcaaga tgctggcttc ccgcgccggt atgccggagc cgcaggagga
    18541 cgacaagacc ggacgtctgc gcagccgggt gctttccatg aataaggagg ccgcccgctt
    18601 cttccacgcc tgcctgaact ctaccgtgga ggaggcacgg caggcgcgcg cttactggcg
    18661 gcggcgcggg ctggacgata agaccatcgt ccggttcggg ctgggctatg cccccaacga
    18721 tgggcaggca ctgtaccagt acctgcggga taagggctac aaccagcagg aactggacgc
    18781 cagcggcttg ttcaaacgca gccagtccgg gcgcatctac tgtctgttct ggaagcgtgt
    18841 catgacccct atctttgatc tgcgcggcaa catcattgcc tttggcgggc gcgtgatgga
    18901 cgactccaag cccaaatacg tcaacagccc ggaaacgctg gtctaccaca aatccgagac
    18961 ggtgtttgcc atgcagatcg ccaagcgcag cgcctcccgg cggttcgtgc tgtgcgaggg
    19021 ctacatggat gtcatcagta tgcagcaggc gggcatcgac accgccgtct gcgcctgcgg
    19081 caccgccctg acccccgggc aagtgcgcat catcagcgag tatgccgatg aggtcattct
    19141 gagctatgac tcggacgagg ctggccagaa ggcgaccctg cgctcactgg aactgttccg
    19201 caacagcccg gtaaaggtgg gcgttttgca gattcccggc gcaaaggacc cggacgaata
    19261 catcaaaaaa tacggcccgg agcgttttca ggcacttctg gacggggtgg gcaatgcgtt
    19321 ggacttccgg ctcaagcgct tgcgagacca gtatgatctc tcgcaggatg cgcagcggct
    19381 gcaatatgta aaggaagccg tggagatgct ggccgagcgc tctaacccca ctgagcagga
    19441 ggtgtacgcc gggcggctgg cagaggagac caacatctcc aaaaccgcca ttctggcgca
    19501 gctgggcacc gcagtaaagc gggcgggcgg caagtaccgc cgggagaaaa atcgcgagct
    19561 gctgcgctcc ggtgagatgg atcagatcaa ggtgccttac agcgcaggcg gcagtcaggc
    19621 gctgggcatc gccagcgccc agcagcggct gctggcagcc atcctgcggg agccccgcta
    19681 tctggaattg gccaaacagc agctgacggc ggagcaattc atccagccgc agcagaagga
    19741 actatacgaa gcgatgctca attgcagccg ggagggcgtg gaactcagcc tgactgcact
    19801 gcgggcattt gtaagtgaag aagcattgaa tgaactgagc cggcttgcgg cacaatacag
    19861 cgatgtgaac tgcaccccgg acgatatccg tctgtatctg gacaggatcg cccggggaat
    19921 gccggttgct agcaaagctg ctgcaatgtc cggcgatgag atcacacagt atcttcagtc
    19981 gatgcgcgaa aaaaagcagg ggactctgcc cgaacaagac tgatccctgt tttccctccg
    20041 gctggagctg gagagaaaag gagcaggaat catgcagaaa ttgtcgcaaa cggaagaact
    20101 tgcccgcagc cttgccgcaa aggctcaccg tcacaccctg accacagagc agatcagccg
    20161 tgccatggaa gaagcggatt ttgatattgc acagctggac gagctttacg cggcgctgga
    20221 gcagcggggc gttcatctgg cagaggagga gcctgccgag ctgcctgtgc tggatgatgc
    20281 ccagatcggc aggctggaga atgaactatc ctcggagggt gtggcactgg atgatccggt
    20341 caagacctat ttaaaggaga tcggccgggt gccgctgctg accgccggac aggagatggc
    20401 gctggcaaag gctgcccggg ccggggatgc agatgcccgc cgcgccttga gcgaagcaaa
    20461 cctgcggctg gtggtatcgg tagccaagcg ctacgccggg cgtggactgc cttttctgga
    20521 tctcattcag gagggcaacc tcggcctgat gaaggctgct gaaaagtttg agccggagcg
    20581 gggcttcaag ttctccacct acgcaacctg gtggatccgt cagtccatca cccgcgccat
    20641 tgcggatcag ggacgcacca tccgtatccc ggtgcatctg gtggagagca tcaaccgggt
    20701 caagaaaacg gcaggcgatc tgctgcacaa aaatgggcgg gagcccaccg tggaggagat
    20761 cgccgccgca ctggatatgg agccggacaa ggtgcgggaa ctgttgcaac tgtcgcagga
    20821 acccatcagt ctggaaacgc cggtggggga ggaagaggac gcccatctgg aggactttat
    20881 tcaggacgag gacgccggtg tcccggtgga cgaagccggg cgccagctgc tgcggcggga
    20941 actgctgcac gtccttaaaa gcctgacgcc ccgggaggag agggtcatca ccctgcgctt
    21001 tggtctggag gatggccgtg cccgcaccct ggaagaactg ggcaaggagt tcaacgtgac
    21061 ccgggagcgg gtgcgtcaga tcgaagcaaa ggcgctgcgc aagctgcgcc accccagccg
    21121 cgcaaagctg ctgcgggatt atctggacga gtgagcattc tatataatag gacaaggccg
    21181 ctgcacggcg ttccgtgcgg cggcctcttc tttttgcggc agggaagcgg aaaagtaata
    21241 cctccgggcg caagagcaaa gatagacaaa ttgcacaagg gtgttatgaa caggaacgtg
    21301 caaaataaaa aaatcaagta cttgaaaagt aaacggctac acgctgccgg gcgttcgaaa
    21361 acaaaccgaa aattaaattt atttcggcaa aaaactgaaa aatggcttga caacaggggt
    21421 tttggggtgt atactgcatt agtatcacat aatggactag tgcgtcaaaa agggagctgt
    21481 gatggctgcc acttgagggg tcaccccgaa aagtttgtgc aaaatgccgg aaggttccgc
    21541 aggacgcggg tcgaattatg tgtgtctgct caaatttgac ccgcgtatac gacatcccgt
    21601 agaatataaa agtaaggagt ggttgatttt atgatgaaag tcaagcccgt aaagctcggc
    21661 aaaaccgagc gcatgagctt ctcccacatc gacgaagtca tcagtatgcc gaacctgatc
    21721 gaggtgcaga agaactcgta tcagtggttc ctggatgaag gcctgaagga ggtcttccac
    21781 gatatcggca ccattgagga ctacaccggc aatctggcac tgagctttgt ggacttccgg
    21841 ctggataagg agccgaagta cagcatcaag gagtgcaagg agcgcgacgt tacctttgca
    21901 gcccccctgc gcgtcactgc ccgtctgctg aacaaggaga ccggcgaggt gaaggatcag
    21961 gagatcttca tgggtgactt ccccctgatg accgacgcag gcacctttgt catcaacggt
    22021 gctgagcgtg caatcgtcag ccagctggtc cgctctcccg gtgtgttcta cggccatgcg
    22081 aaggataagg tcggtaacga cctgtacagc gccaccatga accccaaccg cggtgcatgg
    22141 ctggagtacg agaccgatgc cgccaacgtg ttctatgtcc gtatcgataa gaaccgtaag
    22201 ctgcccgtca ccgtgctgtg ccgtgcactg ggcctgtcct ctaacgagga tatcctgaac
    22261 tacttcggcg aggacgagcg cattctggcc acgctggaaa aggataccac caagaaccgc
    22321 gaggagggcc tgctggaggt ctaccgcaag ctgcgccccg gcgagccccc cacggtggag
    22381 tccgctacca gccagatcga tatgctgttc ttcgatccgc gccggtacga cctgtcccgc
    22441 ttcggccgct ataagatgaa taagaagctg tctctggcac gccgcatcat ggaccatgtg
    22501 gccgcagaga acgtggtgga tcccttcacc ggcgagatcc ttgtcgaggc cgacaagaag
    22561 atcgaccgca agctggccga gcggatcgat gctgccggcg tgaatctggt cgtgctgaag
    22621 atcgatgatc ccatgaagga tcagccccac aaggtcaagg tcatcaccaa cggctgcgtg
    22681 gatgcacagg ccatcatcga cagctactac cccgcattca agggtgtgga tgtcaaggag
    22741 tgcggcatca acgagcgctg ctgcctcaag gagctgcgca agatccttga taacgcctcc
    22801 agcgccgagg aggtcatgga gagcctgaag aaggatcacg acctgctcat cggccgtacc
    22861 gtcaccatcg acgatatcct gtcctccatc aactacctga acggtctggg ctacggcatc
    22921 ggcaccaccg atgatatcga ccatctgggc aaccgccgta tccgcagcgt gggcgagctg
    22981 ctgcagaacc agttccgcat cggtttctcc cgtatggagc gcgtcatccg tgagcgcatg
    23041 accctgcaga gccaggatca gagcgtcatc actccgcagg cactgatcaa catccgtcct
    23101 gtggtggcag ccatcaagga gttcttcggc tcctctccgc tgtctcagtt catggatcag
    23161 aataaccctc tggctgagct gacccacaag cgccgtctgt ctgctctggg ccccggcggt
    23221 ctgagccgtg accgcgcagg cttcgaagtc cgcgacgttc attacagcca ctatggccgt
    23281 atgtgcccca ttgagacccc tgaaggcccc aacatcggtc tgatctccta tctggcatcc
    23341 tacgccaaga tcaacgagta cggcttcgtg gaggctccct accgcaaggt caagaagatc
    23401 tacgacgaga acaacaatct catcgagcag gtcgtcaccg acgaggtgga gtatatgacc
    23461 gccgatgtgg aggacgagta cgttgtggca caggccaacg agccgctgga tgaaggcaag
    23521 cacttcatcc gtccccgtgt gtctgcccgc cgccgcgacg agatcttgga aatcgacgca
    23581 gagaaggtcg attacatgga cgtttctccg cgaatgatgg tctctgttgc taccgcttgc
    23641 atccccttcc tggagaacga tgactgtaac cgtgcactga tgggctctaa catgcagcgt
    23701 caggcagtgc ctctgatggt cacccagcag cccattgttg ctaccggtat ggagtacaag
    23761 gctgctaccg actccggcac cgctgtgctg gccaagagca acggcgttgt ggaaaaggtc
    23821 gacgccgacc atgttgtggt gcgcaacgag cagggcgctc tggaggatta ttctctgatc
    23881 aagtttgccc gctccaacgc aggcacctgc atcaaccagc gccccatcgt agaagtgggc
    23941 gagaccgtca ccgccggtca ggtgctggcc gatggccccg caatgcgcaa cggcgagatc
    24001 tctctgggta agaacgccct gatcggcttc atgacctggg agggctacaa ctacgaggac
    24061 gccgtcctgc tgaacgagaa gatcgtgcgt gaggacgtgt acacctccat ccacatcgag
    24121 gagtacgaga ccgagagccg cgataccaag ctgggacccg aagaaatcac ccgcgacatc
    24181 cccaacgttt ctgaggacgc cctgaaagat ctggacgagc gcggcatcat ccgcatcggt
    24241 gccgaggtca agagcggcga tattctggtc ggtaaggtca ccccaaaggg cgagactgag
    24301 ctgaccgctg aggagcgcct gctgcgcgcc atcttcggcg agaaggcccg cgaggtgcgc
    24361 gacacctctc tgcgtgtgcc tcacggcgca tacggcatca ttgtggatgt caaggtcttt
    24421 accccggaga acagcgacga gctgcagccc ggtgtgcgcg aggtcgtccg ttgctatatc
    24481 gcccagaagc gtaagatcag cgtcggcgat aagatggcag gccgtcacgg taacaagggt
    24541 gttgtttccc gcatcctgcc gcaggaggat atgccctacc tgcccgacgg cactccgctg
    24601 gatatcgtgc tgaacccgct gggcgtgcct tcccgtatga atatcggtca ggtgctggaa
    24661 gtcaaccttg gctacgctgc caaggcctgc ggcatcaagg tcatgacccc tgtctttgac
    24721 tctgcccgtg agaacgacat cggcgatacc tttgataccg cccgcgagat gtggcacggt
    24781 gagaatgcac ctgcataccc caccaagctc cccaagatca tgggcgagaa gggccacatc
    24841 atcgacttct ccaagatcga g
//
