LOCUS gnlProkkaHEGBPLAD_144 11584 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|HEGBPLAD_144. ACCESSION gnlProkkaHEGBPLAD_144 VERSION gnlProkkaHEGBPLAD_144 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 06:24:46 Original ID :: gnl|Prokka|HEGBPLAD_144 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 11584 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..11584 /aStool="rule-based-clusters" /category="RiPP" /contig_edge="True" /core_location="[4185:4891]" /cutoff="20000" /detection_rule="(TIGR04223 or AgrB)" /neighbourhood="10000" /product="cyclic-lactone-autoinducer" /protocluster_number="1" /tool="antismash" proto_core 4186..4891 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(TIGR04223 or AgrB)" /neighbourhood="10000" /product="cyclic-lactone-autoinducer" /protocluster_number="1" cand_cluster 1..11584 /candidate_cluster_number="1" /contig_edge="True" /detection_rules="(TIGR04223 or AgrB)" /kind="single" /product="cyclic-lactone-autoinducer" /protoclusters="1" /tool="antismash" region 1..11584 /candidate_cluster_numbers="1" /contig_edge="True" /product="cyclic-lactone-autoinducer" /region_number="1" /rules="(TIGR04223 or AgrB)" /tool="antismash" CDS 2..451 /locus_tag="ctg122_1" /transl_table=11 /translation="MICPKIRIKFAIYQYTNLPVIVKGIQSPEDALLAIGAGAQGIYVS NHGGRQLNGGPASFDVLHEIAQAVNGRVPIIFDSGVRRGSHVFKALANGADLVALARPI IYGLALGGAQGVASVVSHLNDELLIDMQLAGTKTIEDVKRAKLLR" CDS 1080..1313 /locus_tag="ctg122_2" /transl_table=11 /translation="MSVENNYCKLQQAHDQKCRVSLRFYKTNGQMAETVGYVTTIVPKA IAFMAITGHRHLIQLNRIITVSLQSQDCRYVM" CDS 1704..3818 /gene_functions="other (smcogs) SMCOG1223:ATPase (Score: 965.6; E-value: 3.7e-292)" /gene_kind="other" /locus_tag="ctg122_3" /transl_table=11 /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP DEFAQYRSTGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREK EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK LEAAKEAAVKSEDFKKAADIKKSIEETKQKIKETDQKEKITATIDDVAQSVERLTGIPV SDMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT GVGKTELAKQLALDMFGNENAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVISFKNTIIIATSNAGFGN EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL VDGEIVISAA" CDS 4186..4782 /gene_functions="biosynthetic (rule-based-clusters) cyclic-lactone-autoinducer: AgrB" /gene_kind="biosynthetic" /locus_tag="ctg122_4" /sec_met_domain="AgrB (E-value: 1.9e-35, bitscore: 111.6, seeds: 181, tool: rule-based-clusters)" /transl_table=11 /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV IGTGISEVYRLLLSLIFVIIISIFAPADTVKNPITSKSLRKKLKRRAIGLSLILSLLQI VSNNYFGTIILIAMALAALLLMPYERRENYERKNV" CDS 4763..4891 /gene_functions="biosynthetic (rule-based-clusters) cyclic-lactone-autoinducer: TIGR04223" /gene_kind="biosynthetic" /locus_tag="ctg122_5" /sec_met_domain="TIGR04223 (E-value: 8.7e-09, bitscore: 25.3, seeds: 127, tool: rule-based-clusters)" /transl_table=11 /translation="MKEKMYKVLSHLFQYVGTKQLVMCCHGILFETKIPDELKSKD" CDS 4901..6163 /locus_tag="ctg122_6" /transl_table=11 /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ VILSNLIILSVVMGLVLVIYNEYSKNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE TRVLGAVFLQRLTVKRVSQND" CDS 6156..6899 /locus_tag="ctg122_7" /transl_table=11 /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDMSICLACQDPHELL DKVNAQQPQKAIYVLDIALNSDVNGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYRCHKSYVVNLKRIKSLDKHLRRLT MTNGEKVLCSAQANRYLAKWLAKKS" CDS 7255..7692 /locus_tag="ctg122_8" /transl_table=11 /translation="MIRLYTQSSCHSSRVARQWLEAHGIEFKEKNFSVDSPTVQDLKRI LSLTEHGVDDIISARSKDYPEIAPKLPEMPLNEALKLLCDHPKLLRRPIIISDSKIQVG FNEDDIRQFIPRPVRRLKFNALLSRLDGNTGDHIINKRMVE" CDS complement(7850..9304) /locus_tag="ctg122_9" /transl_table=11 /translation="MTEKLTTETGQPWANNEHSQTAGARGPVLMQDYNLLEKLAHFDRE RIPERVVHAKGAGAKGFFELENDMGEYTKADLFNGVGKKTPVILRFSQVAGEKGYPDTV RDVRGFALKFYTQQGNYDLVGNNTPVFFVNDPLKFPDFIHSQKRDPKTNRRTQNMQWDF WAHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVNQNGEQFWVKYHFISDQGIKN MTAQAAEKAMSQDLDYLQDDLYDAIQEKNYPSWTMYVQILSYEEGLNYKWDIFDVTKVI SHKDYPLIKVGKLTLNENPTNNFTDIEEAAMSPANFVPGIEPSPDKLLQGRLFSYKDAQ RYRLGANFEDLPVNKPVVPVHNYERDGYMKINNQGAEVNYEPNALHGPEEVPDAALSPD SVRGETRAQPYRYQVDYTTQAGDLYRLMSEPEQERLINTIKDALGQVTLPGVKELEIKQ FYEADKNYGTRVANALGMNIADIISD" CDS 9650..9895 /locus_tag="ctg122_10" /transl_table=11 /translation="MHWLWVLIIGAIIGAIAGAITNKGKSMGWISNIIAGLVGSAIGEA LLGSWGPQLAGMAIVPSIIGGVIVVAITSFVLTRMD" CDS 9912..10046 /locus_tag="ctg122_11" /transl_table=11 /translation="MIKSILKFCLAAILIVSGVLIGGTVLTAKGIDNLGDKLQDKLHG" CDS 10241..10789 /locus_tag="ctg122_12" /transl_table=11 /translation="MSKLIAKNVFQLPKMNLLVLTTSAFLLALDVILYKIAIGPAYFQL SFGFLSMACIGYLYGPIWGGLLEMISDILSFTIFGSGAFQIAFLLTAFLGGFIDGLFLY RKSVNWLSVVMTQILVMIFVSLMMDSWLISVLFGTNFKVLLLGRLARVIIQIPLQVIAI FYFIKALEKRHVFDRMRLR" CDS complement(10985..11356) /locus_tag="ctg122_13" /transl_table=11 /translation="MRLWHEQLIHQLPRQQLLGQHRELAALRGNGWGKNHATVNYVFKY SPYKLYQFHVLVMDEMQLRGYHPNKIWYDPNYRGQFCPPYDHLTPIALTTPIYPEHNAS YLAECVRNLAAKGIIMPTT" ORIGIN 1 acaaatttgt ccaaaaattc ggattaaatt tgcaatctac caatatacga atttacccgt 61 tattgtgaag gggattcagt caccagaaga tgccttgtta gcaatcgggg ctggtgctca 121 aggtatctat gtttcaaacc atggcggtcg gcaattaaat ggtggtccag cttcctttga 181 tgttttacac gagattgcgc aagccgttaa tgggcgcgtc ccaataattt ttgatagcgg 241 tgttcggcgt ggctcccatg tctttaaggc gttagccaat ggtgcagatc tggtggcact 301 tgctcggccg attatctatg gattagcatt gggtggtgcg cagggtgtcg cttccgtagt 361 gagtcacctt aatgatgagc tgttgatcga tatgcaacta gcgggaacta agacgattga 421 agatgttaaa cgtgctaaat tacttaggta gtagaagtaa tgctgaatat aatgtctgaa 481 atgaatttaa aatacctgat ataataacac tttagcgttg gttttggtgg aagtaaattc 541 tgctgagatc aacgcttttt attgtaatag gaagatgttc tgaacagaaa tagctgagaa 601 actaagacac tgattgacga attgaagcta tgccggcgtt gaagttagga tattgtctta 661 aaatgcacaa aaagcgtcct aaagcaccca gctgagtttt tcaagtctta aaacggttat 721 tcagacatac ttggcaatag tatactgtac acatgcgcac ataccagttt tatttaggag 781 gctgaatgtt tcataatcta gttatgatga caaggttgta atcatgagtt ttgttgtgag 841 ttatttttct cataaattaa cttcaaagtt tcatagtaat taggatattt agagatcgat 901 ttttgattag taaccatcaa tgcatattat actgagctga acatgaatac tagttattta 961 gtttttactg aatagctgac tccttaatgt ggacttacgc cgtcaacaat gagaaaaaca 1021 aacacataga ttcactgacg aataaataaa cctgaattct ttgaacggga gactttaatt 1081 tgagtgttga aaataattat tgtaaattac aacaagcgca tgatcaaaaa tgtcgagtct 1141 cattacggtt ttataaaaca aatgggcaga tggccgagac agttggctat gtcactacga 1201 ttgtaccgaa agcaattgca tttatggcaa ttactggtca tcggcacctt atccaactca 1261 atagaatcat tactgtgagt ttacagtccc aagactgccg ttacgtcatg taatatgttt 1321 tggtttatga ttttacacgt gtgtcatgat tgctagtatt gatatttaag tggcaatatt 1381 aacgataact agttggcctt aacttgatac tgggtgtgct tgttgagtcg tagtctctta 1441 aattaaaatt ggtctggaaa gtaacttgtt aattcaagtt ctttatcaag ggctattaaa 1501 tagggaacct tgtagggaaa tcaattcatt ttatgaaatt gatttctctt ttgtttaaac 1561 aaaattattc taattatttc taattgattc tataagcact ttacttaacg atacataaaa 1621 atcgtgatac aattcagttg tagttttaaa ggatattatg gtcactaagt tacacatata 1681 aatttttatg gaggtgttgt aatatggcaa atttctacgg aaatgatcct tttttcaaca 1741 atgatatgga tgatgttttc aatcaattat ttcggcgcat ggataatcaa aattcggagc 1801 gtgcacggta tttagttaat ggacaatcgc tgacaccgga tgagtttgct caataccgat 1861 caactggtaa gctaccccaa aataataaaa caatagaagt atctaaagat ggtaaacagg 1921 ctgttaaaaa aggggggatt ttagaaaagt tagggactaa tttgacggaa caggctcgtg 1981 atggattact agatccagtg attggacgtg agaaggagat tcaagaaact gcagaaattt 2041 tgagtcgtag gacgaaaaat aatccaatct tagttggtga tgccggtgta ggtaaaactg 2101 cagtcgtcga aggtctggca caagcaattg tggctggtaa agttccagaa acgattcaag 2161 ataaagaaat ctattcgatt gatttatcgt ctttggaagc aggaactcaa tatcgcggtt 2221 cttttgaaga aaatattaaa cagctagtaa aggaagttaa agcagctggt aatattattc 2281 tattcttcga tgaaattcat cagattatcg gcacgggcgc cactggtggt gaagatggtg 2341 gcaaaggatt agctgatatc attaaacctg ctttgtcacg tggcgagctg actgtaatcg 2401 gggctacgac tcaagatgaa tatcgcaata ctattttgaa aaatgcggct ttggcacggc 2461 gattcaatga tgttgtgatt aatgaaccga cggccgctga cactttacgt atattacaag 2521 gtgttaaaaa gctgtacgaa aaacatcatc atgttgtatt accagatgat gttttgaagg 2581 cggctgtgga ttattcaatc caatatatac cacaacgcac tttgccagat aaagctatcg 2641 atttgatcga catgactgcg gctcatttag cggctaaaaa ttcgcaaact gatgttgaga 2701 cattggatca acgcgttaaa aaattagagg cagctaagga ggccgccgtt aaatcggagg 2761 actttaaaaa agccgctgat atcaagaagt cgatcgagga aaccaagcaa aaaattaaag 2821 aaacggatca aaaagaaaaa atcactgcca cgattgatga tgtggcacaa tcggttgaac 2881 gtttaactgg tataccagtt tctgatatgg gcgctaatga tattgagcat ttgaaaaatc 2941 ttgataagcg tctgaaaagt aaggtaatcg gtcaagatga agcggttgaa atggtagcaa 3001 aagcaattcg gcgtaaccgt gcgggctttt cagagggtga tcagccgatt ggaagttttc 3061 tgtttgtggg cccaactggc gtaggaaaga ctgaattagc taagcaatta gccttagata 3121 tgtttggaaa tgaaaatgcg attattcggc tagatatgag tgaatatgct gatcgtacag 3181 ctgtgtcgaa attaattggt acctcggctg gatacgtagg ctatgaagat aatgctaata 3241 ctctaactga acgggttcgg cgtaatccat attccattgt attattagat gaaattgaaa 3301 aggctgatcc acaagtatta acgttactat tacaagtgat ggatgatggg cgcttaacgg 3361 atggacaagg caatgtcatt agtttcaaaa atacgattat tatcgctact tctaatgctg 3421 gctttggtaa tgaagcatta agtggtgaca agcaacgaga tcagtcatta atggataagt 3481 tagcaccatt tttccgccca gaatttctga accgttttaa tggaatagtg gaattttcac 3541 atctgactaa gcaagactta agtcaaattg tcgatttgat gttggcggat gtacaaaaaa 3601 cgttagccaa aaaatccatc aaacttgagg taactaaagc ggccaaagat tggctgatgg 3661 aacaaggcta tgatgaagca atgggtgcgc ggccattacg gcgagtaatt gaacaacaaa 3721 ttcgtgataa ggtaacggat ttctaccttg accacttaga tgtcaaaaac ttgaaggctg 3781 atttagtgga tggtgagatt gtgatatcgg cagcttagct taaatcagtg ttcataaata 3841 actttatgta agaggagatt gcttgataga tctccttttt tcgttgattt tcaccatttg 3901 atattaatct attgagtaat gtgaattagt gaaattaagt ctagtttgac ttgtaatcta 3961 aggaaaaatt aagggggagt atcgatgaaa ctgatttata ttaacgatct ttttatatga 4021 aactttagtt tcgtatgaat aattaaactg atgtatcttt aaatttttat ttctagtctt 4081 aaaacaatat tgaataatta atctatttat gtattctttt caattaatta atactgtttt 4141 aaactgttga tacaggtatg tatttgagca ttataggagt gggatatgga aaagccagaa 4201 caaaaactat tgctttataa attaagcgat cggttattcg ctgcgattca aaagaatctt 4261 caactagaaa gacggcaggc attactagtt aaactaggca ttgatactgt attaaatgtt 4321 attcctaagc tgataattac tattatctta gcgttgctgc tacacgagtt ggtcccagtg 4381 ttagttttta tgggtagttt tttagttttg cgtggctttg cctatggacg tcacttgaaa 4441 tcggatttgt tatgtacgat attaactatc tttgtgtttg tgggtgtgcc gtatgtgatt 4501 ggaactggta tttctgaagt atacagattg ttattaagtt taatatttgt aataatcata 4561 agtatttttg ctccagctga tacggtaaag aatcctatta catcgaagtc attgagaaaa 4621 aaattaaagc gacgggcaat tggattgtca ttaattttga gtttgttaca aatagttagt 4681 aataattatt ttggcacaat cattttaatt gcgatggcat tagccgcttt attgctaatg 4741 ccctatgaaa ggagggaaaa ttatgaaaga aaaaatgtat aaagtactta gccatctttt 4801 tcaatacgta ggtactaaac agttggttat gtgctgccat gggatattat tcgaaactaa 4861 aattcctgat gaattaaaaa gcaaggatta gtgtagatat atgttaatga ttgtcttcca 4921 agaattatct atctatttga taattaaatc tttgttgaga aatatatttt ttgtgagact 4981 ttttgatgtt atattcttat ccgtctgtat gctgatgagt tatatttttt tagcaaagtt 5041 aggaattagt ttttcttttt taatgttaat gatgtttata tttttcactt ggtggtatgt 5101 acgagttcta agcggtgcac tatgtataac atttcaagtg ttcatatggt cgattatggt 5161 tgaccatatt tgtgatatat taactcgttt aatgaaagtt cctaatgggt atgtggtagt 5221 gtttgtcata ttgagtgtcg taagcttaat ttttcttaat attgtaatgg atcgcacgaa 5281 tttcagtccc acgtttagta atcagagctt aaatcgcata accgcactat tattaatgat 5341 aatatacttg tatattatgt tgagtgaagg tctggaaaat cagttccagg ttatattaag 5401 taatttaatt atattgtcag ttgtaatggg gttagtattg gtgatttata acgaatattc 5461 aaaaaatgta agagccaaat atgaagtcca aaagcaaaga atacaaatac aaaatgatac 5521 tcgttatatg aatgaaatcg aagctcacta taatgagttg cgacgtttca gacatgacta 5581 tcagaatatg ttgatttcga tagatgaata tttgaaaact gatgatttag aaggtttaca 5641 agaatattat caaaagaatc ttgcaccggt ttcaaatcgg gtgttaaaag aaaaatataa 5701 tcttgaagat ttgagtcggg tcaaagtgaa gtcgattaag agtatcctat ttagtaagtt 5761 gagctatgca caatcgcaag agattgaagt tcattttgat ttaaaggaac cattaattga 5821 cattactgtt aatgaattgg atttagacat tgcattaggg attatgttgg ataatgcaat 5881 cgaagcatcg gtaggacatg ctgatggaga gattatgagt gccattttta tcgaaaaaaa 5941 tagtacggtg ttcttgattc aaaacaatgt ttttgaacag ttaccaccct tatggaagct 6001 gaaagaggca ggttattcca ctaagggcaa gaatcggggg attggattga atagtttaag 6061 taagattgtt aatcgcaatg agaacatgat actcgaaacc agagtcttag gagcggtatt 6121 cttacaacgc ttgacggtga agcgagtatc tcagaatgat tagtgtctat atttgtgaag 6181 atgatccgaa acaattacaa caaatacggc aaatcattac taaggtaatc gtcgatcaac 6241 agctagacat gagtatctgt ttagcatgcc aagatcccca cgaattgtta gacaaggtta 6301 atgcacagca gcctcaaaag gcaatctatg tgttagatat tgcccttaat tcagatgtta 6361 atggtattca actagctagc cagattcgtg acatgggccg gcgcagcaag attattttta 6421 ttacgacaca cacggagtta tctttgatgg tgtttcaata tcaagttgag gcattagatt 6481 ttattcttaa ggattttcca gattccttgt atgagcgatt tagcaaggtt ttacacgtgg 6541 cgcaagatcg ttttcaaacc gatgaaaatg accaagacga ctatgttcaa ataaaaattg 6601 gtgagacggt cagatcaatt aatgttaaaa gcattatatt ttttgaaagt tcaaccagtc 6661 cccataaaat cgtagtccat ttggatgatg gtgaattaga atactatgga ctgttaaagg 6721 atgttcctga tttgagtcct aatttctata gatgtcataa gtcatatgtt gttaacttga 6781 aacgcattaa gtcattggac aagcacttgc gacgattaac catgacaaat ggtgaaaaag 6841 tgctttgttc tgcacaagct aatcgttatc tagctaaatg gcttgctaaa aagtcataat 6901 agttccaagg aagtcgcctg ccaaattagt aggcgacttt ttatgtgcta cgtgatgaaa 6961 attcagcgtt attcgattag aaattgcagt ggtatttgtc agcattacgt gtactgggtt 7021 cgttctttcc taaaccgttt aaaagtgtac ttaaaacgat tatcctcaga ttattcgtct 7081 taaaacggtc ggtatgtccc ttgttcagag cctataataa agatgtgttc acggggtatt 7141 ggattggtca tgacagtaac gaatgcgttt agtttaaagg atgttgtgac aggcagaagt 7201 taatgtcgat caatacgctg tgatgaattt taacgagaga ggggcagatt aggaatgatt 7261 aggttatata cacaatcaag ctgtcattct tctagagttg cacggcaatg gttggaagca 7321 catgggattg agttcaagga gaaaaatttt agtgttgatt cgcccacggt gcaagatcta 7381 aaacgtattt tgagtttaac cgaacatggt gtagacgata ttatctcagc tcgatctaaa 7441 gactatcctg aaattgcgcc taagttaccc gaaatgccat tgaatgaggc acttaaattg 7501 ttgtgtgatc atccgaagtt gttacgtcgg cctatcatca ttagtgatag taaaattcaa 7561 gttggcttta atgaagatga tattcgccaa tttattccac gaccagttcg gcgactaaag 7621 ttcaatgcat tgttgagtcg tctagatggt aacacagggg atcacattat taataaaagg 7681 atggtcgagt agtaagctat atctaagatt ttttgttaat taaggagcga caggctagac 7741 ttacacgata tgagtctaac ctgtcgctct ttagttaata accatgagac ggcatcatca 7801 ttctttataa caaaaataat atcgcgatgg ataacatccg gtcaaaatat taatcactga 7861 taatatcagc aatattcatt cccagagcat tagccacgcg tgtaccgtag tttttgtcgg 7921 cctcataaaa ttgcttgatt tcgagttctt tgacaccagg caaagtaact tggcctaacg 7981 catctttgat agtattaatt aagcgttctt gctcgggttc tgacattaag cgatataggt 8041 cgcctgcttg agttgtgtaa tcaacttgat agcgataagg ctgtgcgcgt gtttcaccac 8101 gaacagaatc aggtgaaagt gcggcatctg gcacctcttc tggcccatgc agtgcattag 8161 gctcgtagtt gacctcagca ccttgattat taattttcat gtaaccatca cgttcataat 8221 tatgaactgg aacaaccggc ttgttcacgg gtaaatcttc aaagttggca cctaaccgat 8281 atcgctgtgc atctttatag gagaataggc gaccttgtag taatttgtcg ggagatggtt 8341 cgataccagg aacaaaattt gctggcgaca tggccgcctc ttcaatatcg gtaaagttat 8401 tagtgggatt ctcatttaaa gttagtttgc cgactttaat tagtggatag tctttgtggg 8461 agatgacttt agtgacatca aaaatgtccc atttatagtt tagaccttcc tcatatgaca 8521 agatttggac atacatcgtc catgatgggt aatttttttc ttgaattgca tcatataagt 8581 catcttgtaa ataatctaaa tcttggctca ttgctttttc agctgcttga gcagtcatat 8641 ttttaatgcc ttggtctgag atgaagtgat acttaaccca aaactgttcg ccattctgat 8701 taacccattt aaaagtatgg gaaccgtaac cattcatggt tcgataggac gcaggaagtc 8761 ctcggtcgcc cattaaataa gtgacctggt gcaatgattc tggagaatga gcccaaaaat 8821 cccattgcat attttgcgta cgacggttcg ttttaggatc ccgtttttgt gaatggatga 8881 agtcaggaaa ttttaaaggg tcgtttacaa aaaagaccgg tgtgttgttt ccaacgagat 8941 cataattgcc ttgctgagta taaaatttta aggcaaaacc gcgcacgtct cgaacggtgt 9001 caggataacc tttttcaccg gcaacttgtg agaaccttaa gattacggga gttttcttac 9061 cgacaccatt aaataagtct gccttagtat attcccccat gtcgttttca agttcaaaaa 9121 aaccttttgc tccggccccc ttagcatgaa cgacccgttc tggaattcgt tcacgatcaa 9181 aatgggctag tttttccaaa agattatagt cttgcattaa tacgggacca cgagctcctg 9241 ccgtttggga atgttcattg ttagcccatg gttggccggt ttccgtcgtt aatttttccg 9301 tcattttaat cacccttttc acgtaaatta caagaaagct cttgcacaat ttaaacgcta 9361 acaccttaac agagtgactt caatcattat gcacagttaa gttaatcgtt catgtggcgt 9421 agtttaattt taatcagcta tcaagctgtt tgatattttc taggccaccc ggaatcgtca 9481 catgagaaat agtagcgacc catttattaa ataatgtgtt atatttgtct atcattatcg 9541 ataattgtaa aatgataatt ataagaagta atcatttatg aatcggctta aatattcgtg 9601 taattctatt attgtattta agcggtttaa taagtctagg agggatttta tgcattggtt 9661 atgggttttg atcattggtg ctattattgg tgcaattgca ggtgctatta ctaataaagg 9721 taaatcgatg gggtggatta gtaatattat tgccggattg gttggatctg caattgggga 9781 agctcttttg ggatcatggg gaccacaatt agccggaatg gcaattgttc cttcaattat 9841 tggtggtgtg attgttgttg cgataacctc atttgttctg acacggatgg attagtaagg 9901 agatgattgc gatgattaaa agcattttaa agttttgttt agctgcaatc ttaatcgtaa 9961 gtggtgttct tattggtggg accgtactta ctgctaaggg aattgataac ttgggtgata 10021 aattacaaga taagttacat ggataaaaat taattttaca atgagccact gatgggtgta 10081 ctagttgacc tgttagtggc ttttagtatg agtaatatca ttgagttcaa ggaactaaat 10141 caagagcgac aattttaaac taccttcaat cgaataaaag taatatttac ttttattaag 10201 aatgagggta tgattaaaat caaaaaaaga ggattggcct atgtctaaac ttattgcgaa 10261 aaatgttttt cagttgccaa aaatgaattt attagtgctg actacatcgg ctttcttatt 10321 ggccttagac gttattttat acaaaattgc tatcggacca gcgtattttc aattatcttt 10381 tggctttttg tctatggctt gtattggtta tctatatggt cccatttggg gtggtctctt 10441 ggagatgatc tccgatatat taagctttac tatttttggt tccggcgcgt ttcagattgc 10501 ctttttgtta actgcatttt tagggggatt tattgacggt ttgtttttat atcgtaaatc 10561 agtcaattgg ttatctgttg tgatgacgca aatacttgta atgatttttg ttagtttgat 10621 gatggactca tggctaattt cagtactatt tggcactaat tttaaagtgt tattgttggg 10681 aagattggca cgcgtcatca ttcagatacc attacaggtg attgctattt tttacttcat 10741 taaggcgtta gaaaaacgac acgtttttga tagaatgagg cttagataac atcgatggat 10801 gctacaaaaa gaggttgaac atggtatgaa atgcgctaca atcgttaaac aaataagtct 10861 aacttttcta ttgcacttca agtctagttc aacctttttt aatattaact ggccttatta 10921 tgactgcgga aaaacaattt gggtatcgat ggttgagttg gtacccagca aaataaaaga 10981 gcggctatgt ggtgggcatg ataattccct tagcagctaa attgcggaca cattctgcta 11041 agtagctagc gttgtgttct ggatagattg gtgttgttaa tgcaatagga gtgaggtgat 11101 cataaggcgg gcaaaactgc ccacgataat ttggatcata ccatatttta ttaggatgat 11161 agccgcgaag ttgcatttca tccatcacta atacatgaaa ttgatacaac ttgtaagggg 11221 aatatttgaa aacataatta acggttgcat gatttttacc ccaaccattg cctctcaatg 11281 cggcaagctc acggtgttga cctagtaatt gttgtcgtgg taattgatgg attaattgtt 11341 catgccatag acgcataggc cacactccct tatcgaattt taaaattaac aggtgaatat 11401 taaaaggacc aactcatcat tatgatgccg aatatactga tacttttgaa cgggtgatga 11461 ttgtaaacga cggatagtta aagtgaatat tcgcaattat tatagcatag cgaattgatc 11521 aatatggatt gaagtcaata tttgagacag attttaagag acattcagaa ccgcgtttac 11581 cttc //