LOCUS       c00044_gnlPro..        14664 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GLMKCGIP_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 06:59:06
            Original ID  :: gnl|Prokka|GLMKCGIP_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14664
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14664
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7182:10107]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7183..10107
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14664
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14664
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(3..1079)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_1"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 1.1e-84,
                     bitscore: 273.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAENNKKYRFETLQLHVGQEQADPATDSRAVPIYATTSYVFHNFD
                     HAEARFGLADPGNIYGRLTNTTQGVFEDRIAALEGGTAGLAVASGAAAVEYAVRNITQS
                     GDHIVAAKNIYGGTFNLLRHTLPRDGITTTFVSAENPQEFEDAIQENTKLVYFETFGNP
                     NADLPDFEAISEIAHKHNLPVIVDNTFATPYLFRPLEHGADVVVESATKFIGGHGTTLG
                     GVIVEGGKFDWNAVPGKFPTLTEPDPSYHGLNFYEALGGAAFVTRVRAILLRDXXXXXX
                     XXXXXXXXXXXRRHPVSVRCLPAAAGHRDPVPARRAPRSERAEGRRVPADRAGSRVRLP
                     PVHRGPSGPRPVREVLPER"
     CDS             1692..2564
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="VSDVTLYDRDPKYIPRVAAVHDMCGYGKCSLTAAIPILSAAGCDV
                     CPVPTALFSAHTKYAVFTFHDTTDILSGYLDAWQKEDVELDGVYSGFLGSPDQVAIIQR
                     LYREYPNALRLVDPVMGDAGEMYPTYTPELCEAMGALADGADVLMPNLTEASILTKRDY
                     PGQDIDEATVDELLGALLELGAKNVVLKGIDHGDGKIINYVASASTGVTGKIELAHDKL
                     PYMIHGTGDAFASALCGAVMAGRGLAESAEIAGEFVRHAMESTRNQPHFEDRGVSFELN
                     LGELTNLVK"
     CDS             complement(2664..2891)
                     /locus_tag="ctg44_3"
                     /transl_table=11
                     /translation="LRFYLELRVWALAGILISSLLLVWVRLENGNAEAMALTDTLLRVP
                     ISVVVGVLVGALVAVLSTRESHLLKYFKNR"
     CDS             3096..3362
                     /locus_tag="ctg44_4"
                     /transl_table=11
                     /translation="VARVQRERVLPPLPAETAEDGRIRRYLPKRTSLDDLTDEDLQAIV
                     QEINDTPMKVPDWETPNEAWYRKLGKVMSKTSHPQTNVALTNR"
     CDS             3580..3954
                     /locus_tag="ctg44_5"
                     /transl_table=11
                     /translation="MGDRNLSPKQFGALGERYAAVWLEKKGWTTLSHNWRTRYGELDLV
                     MLNDEHTVVFVEVKSRRTIQYGCPQEAVTPAKQQNLRKAACDWLLDCRNRISHKAVRFD
                     VITIVLRVGRPLVHHIENAF"
     CDS             3969..5504
                     /locus_tag="ctg44_6"
                     /transl_table=11
                     /translation="MAIGSALSVGLIGLKAFIVQVQAFISPGLPYFSIIGLPDTSLSEA
                     RERVKSACQASGFSWPQTRVTVNMSPASLPKRGSSHDLAIAASVLCAAGAIGHDCLEDT
                     IVLGEVNLDGSVLPIHGLLPIMLHAQERGIRKVIIPYRNLDEASMVEDMDAIGVRHVGE
                     LIELMGGNASYTIPDLQLAEDASASEQAEVSENGYADMNEVLGQEHAKWTLQVAAAGGH
                     NLIMTGPPGTGKTMLASRLPGIMCPLEDTEQLEVASIRSLCGTLSQYGITDVPPFEAPH
                     HTASTASLVGGGSGIAAPGAITRAHRGILFLDEAPEFSARALQTLREPLESGYVALSRS
                     KGSTYYPAAFQLVMAANPCPCGYYYGTGERCRCREKDRMRYFSRLSGPVLDRVDIQMTV
                     PPVPRITVQHEPLGESSATIRARVIRARNAAKDRFQQFGWTCNAQASGTWLHANTSLKA
                     MELVNRALSSQQLTLRGADRAMRLAWTLADLAGRISPTEQDVHQGIEMRTRVS"
     CDS             5501..7120
                     /locus_tag="ctg44_7"
                     /transl_table=11
                     /translation="MSTTNMIAEPASVHGSPHTIGKAEAAAQTVRSRIIAAPSLDALYR
                     AALTFCIDGADAMMYATLKGAEHAEALWQVLSQCHPDRPSDVRQKALTCIDRMFINGLT
                     RWGRKPTPSAMNAFRNALSGWHQRMDALPSQDIVSLADWFTMDGTQWIIGPGHPCWPAQ
                     LTDLSIRSDWAPPLCLWVKGDPRALTSCAKPVGIVGSRDVNEYGRYVAHTVAEQAAVDG
                     HLVVSGGAMGTDAAAHWGALNALHGRKPGCVGRTVAVFAGGLNHMGPARNRTLFERIES
                     QGGALISELCPGTIPEARRFLLRNRIIAALSSTLVVAQARLRSGALNTAGWACELMREV
                     YAVPGDINQPCNAGCNKMIGDHQATILCAATSTKDICHKRHQPIMERCPGMADNAQRDA
                     SDPAPSCTTKAVHKKSEQPTLSQAVITTPLPSRTDSKDFSSSHHMPDLRAQASLQPDAE
                     TQQTIQVSTLSEAERLMVGLIRECRTHRLAITPDTLLRAARNNNLEEIPDIATVLELLG
                     ALELRGAIHRETGTVTLSCRLI"
     CDS             7183..9084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 338.5; E-value:
                     2.2e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_8"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.6e-104,
                     bitscore: 338.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.5e-29,
                     bitscore: 92.4, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALFGGCARIESMSPKRLEDMYDAVIVGAGAAGLSAALGLLRSP
                     EIAELKEQGVDPKILVVSKLQPLRSHTGSAEGGIAASLGNVESDDWHWHYYDTIKGGDW
                     LVDQDAAKLLAEYAPQTVINLERQGVAFSRTEDGHIAQRRFGGHTREFGGAPVKRAAYA
                     ADRIGHQILHALWQQCVAAGVEFAEEWYVTDLALADDGKQAAGIVAFDTHTGKIQAIHA
                     RNVLLATGGAGRLFHTTSNSWDLTGDGMALTLAAGLQLEDIEFVQFHPTGLAHTGILLS
                     EAARAEGGILRNADGEPFMERYAPEHKDLAARDVVSRSIMAEIDAGRGVADPKDPDGPK
                     DCVWLDMTDIDPERMKEVLPQVVETIEQYANLDPAKDLVPIKPTAHYTMGGIPITTNGE
                     VYRWTDDAVQIVDGLFAAGECSCVSVHGANRLGGNSLLDACLFGTRAGQTMATRIAENP
                     VDSPMADDSADDMLTTAADHAAESRKSELDELLAGQADDVDEGSTANPYQLMAQLGSVM
                     EQALAVRCTAQTIDTALAQLNSDIKPVSDILRAHDKTAAFNQEVTAIWEVRHLIELAEA
                     MLHASESRQESRGSLQRLDFPERDDEHFLAHSLVADAGPVSFKPVHITDYPPKKREY"
     CDS             9157..10107
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 145.5; E-value: 1.8e-45)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_9"
                     /sec_met_domain="Fer2_3 (E-value: 3.8e-46, bitscore: 145.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 7.7e-13, bitscore: 38.6,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-06, bitscore: 17.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEANNTTVTLQVHRFTPRPERAERARGGSPFAKKSSPFGGGSDS
                     AARRRPRGKQWVQEYTIPARPSDTVLDCLLTIKRTIDPTLAFRYSCGHGMCGSDAAAIN
                     GTPTLLCTATVRDWAKQPSTAPEVDDEGFRRTGDETANEPDVPAENVENNITEGSLGVI
                     ELASLPGFPPQRDLIADIDPMLNQIRKLTPYLQADGVLATTAEGKVDVFEYLQNPEQLA
                     KYETLSNCIACGVCEGACPVYAGGDAFVGPAALIWASRFINDSRDTKAMDRMDAIDTAD
                     GVAGCQSVRACSRHCPRGIDVGEEMWQIVAKVRER"
     CDS             10170..10835
                     /locus_tag="ctg44_10"
                     /transl_table=11
                     /translation="MDRTQYTNLAKAWEFTEEHARELESSTLADARTAADESGQLQGPA
                     AQARLLGLLVRLTGTSSVIAVGTGSLVETLQLAYALDNKGQLTAVDSTAQGITLIRKAF
                     AELQDETATTLRAVNAPASVFLPRLNANDYDLIVVAGDAENYAATFAQASRLLRDHGAI
                     VFTDALALDTEQGGVINPADRSGKATAMRELITTVEQDEEFESTLTPDGTGLLIAYKK"
     CDS             complement(10876..11778)
                     /locus_tag="ctg44_11"
                     /transl_table=11
                     /translation="MAKKQKKSQKADGKKASGIKQPTNTGVDGNPNVGTIAEEQANIQV
                     AQIPMNPVDLEDAAPLGDTYHRGPVILRGQMIPSDNTTANLLKPDQDTDWLHMDPWRVL
                     RIQSEFVDGFGALAELGPAVSIFGSARTQRTESDYKAARRMGSQIAKRNIAVITGGGPG
                     IMEAANRGAALAGGKSVGLGIELPFEQGLNQWVNLGMSFRYFFVRKTMFVKYSSGVIVC
                     PGGFGTLDEMFELLTLVQTHKVANIPVVLYGKDYWQGLFDWLDGPVAERGMISKIDPKL
                     VTVTDDADEAVDVATSMVA"
     CDS             complement(11818..13206)
                     /locus_tag="ctg44_12"
                     /transl_table=11
                     /translation="MATTTGAKRGIWPMIRRIAASDRISGLIMLGFALAGLVLANLPLT
                     AHAFEAVAETHVFIPHTNLDLPIGHWAQDGLLTIFFLTVGLELKQELTTGSLANPKAAA
                     VPMLCAVGGMITPPILFLATTALFSQFGPGEPGSLILATTGSSIPFAEMSHGWAVPTAT
                     DIAFSLAVLALFAKALPGSIRAFLMTLATVDDLLAIILIAVFFSSVNAWYWFIGIAVCA
                     VVWAHLVRLKKVPWIAVGVVGILAWIMMFEAGIHPTLAGVLVGLLTPARVMHGEYSPRA
                     ERYADKLKPFSALLALPIFALFATGVHFESMSPLLLLSPLVIALIVALVVGKPLGIIVT
                     AWLATHVGGLKMAKGLRVRDMIPAAVACGIGFTVSFLIASLAYTNQELSAEARFGVLVA
                     SLIAAAISGVLLSRQSKRFEQAAAVAAAEADAESDVNTHSDELAEHSITLADGTESVEI
                     DFRR"
     CDS             complement(13288..14493)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_13"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.3e-34, bitscore:
                     107.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VILAQHAPYDFDTILERHGSSSAKWHEVVEQMGEDGKDVVPLSVA
                     DMEFKPAPEVVEALIQSATHDVFGYDYATEDYFTAFLNWMEHRHNFHIDPSWVSLSDGV
                     MPAVNTALRSVTRPGDKVIIQRPVYYPFTFAAEHNGLTILDNELVLDENGHYGIDFDDL
                     ESKAADPRCTAMILCNPHNPVGRVWTPEELRRIGDICIKRRVRLLCDEIHADFSYPGHK
                     VTMFSTLGAEYANIVFEFTAPTKTFNLAGLLCSNTIIPNPHLKRRYDAAADNIGGLTVN
                     HFGMVACQAAYNHAEPWLDALMEVLERNLGLIRDFTARVSGIRLIEPEGTYLAWLDCRG
                     LGFDTPEELCDFLRNEARVWFDEGSMFGESGNFFERVNLACPTRLLEQVLANIETALAD
                     RQ"
ORIGIN
        1 ctccgttcgg gaagtacttc tcgtacaggg cgtggtccgg acggccctcg atggacgggt
       61 gggagacgga ctcgacttcc ggcacggtct gcaggtactc gacgaccttc agcgcgttct
      121 gaacgtggcg ctcgacgcgc agggacaggg tctcggtgcc ctgcagcagc aggaaggcag
      181 cgaacggaga cagggtggcg ccggnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      241 nnnnnnnnnn nnntgtcgcg cagcagaatg gcgcggacgc gggtcacaaa ggcggctccg
      301 ccgagggcct cgtagaagtt caggccgtga taggagggat ccggctcggt cagagtcggg
      361 aacttgcccg gaacggcgtt ccagtcgaac ttgccgcctt cgacgatcac accgccgagg
      421 gtggtgccgt ggccgccgat gaacttggtg gcggactcga ccacgacgtc agcgccgtgc
      481 tccagcgggc ggaacaggta cggggtggcg aaggtgttgt ccacaatcac cggcaggttg
      541 tgcttgtggg cgatttcgga gatggcttcg aagtccggca ggtcggcgtt cgggttgccg
      601 aaggtctcga agtagacgag cttggtattc tcctggatgg cgtcctcgaa ctcctgcggg
      661 ttctcggcgg agacgaaggt ggtggtgatg ccgtcgcgcg gcagggtgtg gcgcagcagg
      721 ttgaaggtac cgccgtagat gttcttggcg gcgacgatgt ggtcaccgga ctgggtgatg
      781 ttgcgcacgg cgtattcgac ggcggcggcg ccggaagcga cggccagacc ggcggtgcca
      841 ccttcaaggg cggcgatgcg gtcctcgaag acgccctggg tggtgttggt cagacggccg
      901 tagatgttgc ccgggtcagc gaggccgaaa cgggcctcgg cgtggtcgaa gttgtggaag
      961 acgtagctgg tggtggcgta gatcgggacc gcgcgggagt cggtggccgg gtcggcctgc
     1021 tcctgaccca catgcagctg cagggtctca aaacggtact tcttgttgtt ctcggccatg
     1081 gtattctcct tggttgtgct aggtcgcgag gatattttcc ttgccacccg cctgccgtgt
     1141 tcgggcggtt ggcgaggtgt tggtcatgaa gttacgacgc tcaaggtgca tgtcgcaagc
     1201 tgagcgttat cggggttgcc tatagaccct tataaaccct tggaatcatt gggatatgag
     1261 gcggttacgt cgggcaaaat agtcatcaaa aatctcacga cacgccgaga cacttccacg
     1321 tctcttcgcg acagaaatct aggaaatcat cctcaatctc ctgaaatcct gtcactgagg
     1381 tgacgtcagc gacagaattt caggacgaat gggtttattt ccgaaatttc tgtcactgag
     1441 acggattcaa cgacagcaat tcaggggatc agggatgatt tccgaaattt ctgtcgctca
     1501 gatggaacca gcaacggaat tttggggtgg atggttttat ttccaagatt tctgtcgcta
     1561 ggagtttgag cgatctgttg aattcggcga cggaacctca ccagatgaat accggttagc
     1621 gtgtccgtat ccctacagac tagtgtcaac tgtgattatg tgacatccgt ctgattgatt
     1681 ggagttttct agtgtccgac gttacgttgt acgaccgcga cccgaagtac atcccgcgcg
     1741 tggccgccgt gcatgacatg tgtggctatg gcaagtgctc gctgaccgcc gcgattccga
     1801 ttctttcggc agccggctgc gatgtctgcc cggtgccgac cgccctgttc tccgcacaca
     1861 cgaagtacgc ggtgttcacc ttccatgaca ccacggatat cctctccggc tatctggatg
     1921 cctggcagaa agaagacgtt gagcttgacg gcgtgtactc gggattcctg ggctcccccg
     1981 atcaggtggc gattattcag cgtctctacc gcgaatatcc gaatgcgcta cgtttggtcg
     2041 acccggtgat gggcgacgcc ggtgaaatgt atcccacgta tacgccggaa ctgtgcgagg
     2101 cgatgggtgc gctggccgac ggcgccgatg tgctgatgcc gaacctgact gaagcgagca
     2161 ttctgaccaa gcgcgactac cccggtcagg atatcgatga agccacggtt gacgagctgt
     2221 tgggcgcgct gctggagctt ggcgcgaaga acgtggtgtt gaagggcatc gaccatggcg
     2281 acggcaagat catcaactat gtggccagcg cctccactgg tgttaccggc aagatcgaac
     2341 tggcacatga caagctgccg tacatgattc acggcacggg cgatgcattc gcttccgccc
     2401 tgtgcggtgc ggtgatggcc ggtcgcggac tggccgagtc tgctgagatt gccggcgagt
     2461 tcgtgcgtca tgcaatggaa agcacgcgca accaacctca cttcgaggat cgcggcgtca
     2521 gcttcgagct caatctcgga gaactcacca atttggtgaa gtgacccact ttggctcccg
     2581 ctggcgggag ctgtcaacga agttgactga gggtggtcta ctatctgcac gcaccaccct
     2641 cagtctagcg ggagcatccc aatctaccga ttcttgaagt acttgagcag gtggctttcc
     2701 cgcgtgctga gtacggcaac taacgcccca accagcacac caaccactac gcttatcggc
     2761 acccgaagca gcgtgtcggt aagcgccatt gcctctgcat tcccgttctc cagccgtacc
     2821 cataccagta acaggcttga tatcagtatg ccggcaagtg cccacaccct gagttctaaa
     2881 tagaagcgca acacccgctc tatggttgga agtgttcaag ttcataacca gagagaaagc
     2941 gtcgcgctcg atatgaaagc ctattcccac ctgtcggcag aggaacgcat ccggatcgac
     3001 gagttgagga accgcgaggg gctcggggtc cgccagatcg ccctgaggat cagccacggc
     3061 aagcccaccg tcagccgcga accgaggcgc ggcccgtggc tcgcgtccaa cgagaacgag
     3121 tcctaccgcc cctaccggcc gaaacggctg aagacggacg catccgccgc tacctgccca
     3181 agaggaccag tctcgacgac ctcacggacg aggacctgca ggccatcgtc caggagatca
     3241 acgacacccc catgaaggtc ccggactggg aaacgcccaa cgaggcttgg taccgcaaac
     3301 tcggcaaggt aatgtcgaag acaagccacc cacagacaaa cgttgcactt acaaataggt
     3361 aacgggatcg cgaatgtcat ccgctggatg acatagcgaa gcacatactt tctgaactaa
     3421 tggtggataa ccgcactttc atccacacgc tgtccacaac acgccaagcc gcgtcatggt
     3481 atccacattt gccggtcgcc cttgcgtccc gatatcacca acccgcacag tggaatcatg
     3541 aatgatgcag caacttccac ggaacacatc gcagccgcaa tgggcgaccg caatttgtca
     3601 cccaagcagt tcggcgctct tggcgaacga tatgcggctg tttggttgga gaagaaagga
     3661 tggaccacac tgagccataa ctggcgtact cgatacggcg aactggatct tgtgatgctc
     3721 aacgacgagc acactgtggt gttcgtcgag gtgaaatcgc gccgcaccat ccagtacggc
     3781 tgcccacagg aggccgtgac gccggccaag caacagaatc tcaggaaagc tgcttgcgat
     3841 tggctgcttg attgccgcaa ccgtatctcg cacaaagccg tcagattcga tgtcatcacc
     3901 atcgtgttgc gcgtgggtag accgctggtg catcacattg aaaacgcgtt ttagcgaaag
     3961 gatcaagcat ggccattggc agcgcccttt cggtcggtct gatcggactc aaggccttca
     4021 ttgtccaggt acaggctttc atcagtcccg gcctgccata tttcagcatc attggactgc
     4081 cagatacctc actgtccgaa gcgcgcgagc gagtgaaatc ggcatgtcaa gccagtggtt
     4141 tctcatggcc acaaacccgt gtgaccgtga atatgagccc cgcttcccta cccaaacgcg
     4201 gctcatcaca tgatttggcc attgccgcca gcgttctctg cgcagctgga gccattggcc
     4261 acgattgtct ggaagacact attgtgcttg gcgaagtgaa tcttgacggt tcggtactgc
     4321 ctatccatgg attactgcca atcatgttgc atgcgcagga acgcggcatc cgaaaagtaa
     4381 tcatacccta tcgcaatctt gacgaggctt cgatggtgga agacatggat gcaatcggcg
     4441 taagacatgt gggcgagctc atcgagctca tgggaggcaa tgcctcatat acaatccccg
     4501 atctgcagct cgcggaggat gcaagtgcct ccgagcaagc cgaagtcagt gaaaacggat
     4561 acgcagacat gaatgaggtg ttgggccagg aacatgccaa atggacgctg caggtagcgg
     4621 ccgccggagg ccataacctc atcatgaccg gacctcccgg cacgggaaaa accatgttgg
     4681 cttcacgatt acccggcatc atgtgcccat tggaagatac cgaacagctg gaagtcgctt
     4741 cgattcgctc gctgtgcggc accttatcgc aatatggcat caccgatgtg cctccgtttg
     4801 aagcgccgca tcataccgct tccacagcgt cactggtcgg cggcggcagt ggcatcgcag
     4861 caccgggcgc gataacccgc gctcaccgtg gcattctgtt tttggacgaa gcaccggagt
     4921 tcagcgcccg ggccttgcaa acgttgcgcg aaccattgga atccggctat gtggctctct
     4981 cccgctccaa aggaagcacg tattacccag ctgcattcca gctggtcatg gcggcaaatc
     5041 cttgcccatg cggatattat tacggcactg gcgagcgctg caggtgtcgg gaaaaagatc
     5101 gcatgaggta tttctcccgt ttatcgggcc cggtacttga ccgagtagat attcagatga
     5161 cagtgccgcc cgtcccccgc atcaccgtgc agcatgaacc gctcggcgaa tccagcgcca
     5221 caattcgtgc acgcgtgatt cgtgcaagaa acgccgccaa agataggttc cagcaattcg
     5281 ggtggacatg taatgctcag gcatccggca cgtggctgca tgcgaacacc tcgctcaagg
     5341 cgatggaact ggtcaatcgt gccttgtcct cgcagcagct gacgttgcgt ggagctgatc
     5401 gtgccatgcg attggcctgg accctcgccg atctggccgg ccggatttcc cctaccgaac
     5461 aggatgtcca tcaaggtatc gaaatgagaa cgagagtgtc atgagtacca ccaatatgat
     5521 tgccgagccc gcttcagttc acggctcccc tcacacaatc ggaaaagccg aagcggccgc
     5581 acagaccgtg cgctcacgta ttatcgccgc tccttcacta gatgccctat accgtgccgc
     5641 gctcacgttc tgcatcgatg gcgcggatgc gatgatgtac gccacactca aaggagccga
     5701 acatgctgag gcattatggc aggtcttgtc acagtgtcac cctgaccggc cttccgatgt
     5761 tcgccaaaaa gcactgacct gcattgatcg catgttcatc aatggtctga cccgctgggg
     5821 tcgcaaaccc acacccagcg cgatgaacgc ttttcgcaat gccctgtccg gctggcatca
     5881 gcggatggac gccctgccct cgcaagacat cgtttccttg gccgactggt tcaccatgga
     5941 tggcacacaa tggattatcg gcccgggaca cccatgctgg cctgcgcaat tgaccgacct
     6001 atccatccgc tccgactggg cacctccctt atgcctttgg gtcaaaggcg atccgcgggc
     6061 cctgaccagc tgcgcaaaac cggtgggtat tgtcggctcc cgagacgtca acgagtacgg
     6121 acggtatgtg gcccatacgg ttgccgagca agccgcggtg gatggtcatc tggtagtttc
     6181 aggaggcgcg atgggcacgg acgcggccgc tcattggggt gctctgaatg ctctgcacgg
     6241 ccgcaaacca ggatgcgtgg gcagaaccgt cgccgtattc gccggcggac tgaaccatat
     6301 ggggccagct cgcaatcgca cactgtttga acgcatcgaa tcgcagggag gcgcgctcat
     6361 cagcgaactt tgtcccggca ccattcccga ggcgcgcaga ttcctgctgc gcaaccgtat
     6421 tatcgcggca ttgtcttcca cactggttgt ggcacaggcg agattgcgct caggcgcact
     6481 gaatactgcg ggctgggcct gcgagctgat gcgcgaggtg tatgcagtgc caggagacat
     6541 caatcagcca tgcaatgccg gctgcaacaa aatgattggc gaccatcagg ccacgattct
     6601 atgcgccgcc acctccacga aagacatctg tcacaagcgc catcagccga ttatggaacg
     6661 atgcccaggc atggcggaca acgcacagcg cgatgccagt gatccagcgc cttcgtgtac
     6721 gaccaaggcg gtccacaaga aatccgagca gcctacgcta tcccaggctg tcatcacgac
     6781 tcccttgccg tctcgcacag actccaagga tttctcctca tcccaccaca tgccagattt
     6841 gcgcgcccag gcatcgttgc agcccgatgc ggaaacgcaa cagacgatac aggtcagcac
     6901 attgtcggaa gcggaacgct tgatggtcgg ccttatccgc gaatgccgta cgcatcgcct
     6961 cgccatcaca ccggacaccc tgctgcgcgc ggccaggaat aacaacctcg aggaaatacc
     7021 ggatatcgcc accgtactgg aactgctcgg agcgctggaa ctgcgaggag cgattcaccg
     7081 ggagaccgga acggtcacgc tcagttgtcg cctcatctga atcatggaga cgccagtctt
     7141 acacaccgct agaacaagaa ttgtcagcac cctcatgaca cgatgacggc gctgttcggc
     7201 gggtgtgcaa gaatcgaatc catgagtccg aaacgtttgg aagatatgta tgatgcagtg
     7261 atcgtcggtg ccggtgcggc tggtttgtcg gcggcattgg gactgctgcg atcccccgaa
     7321 atcgccgaac tcaaggaaca aggcgtggac ccgaagatcc ttgtggtctc caaactacag
     7381 ccgctgcgtt cgcacaccgg ttcggctgaa ggaggcattg ccgcaagcct gggcaatgtg
     7441 gagtccgatg actggcattg gcattactac gacaccatca agggcggcga ctggcttgtt
     7501 gatcaggacg cggccaagct gctcgccgag tatgcgccgc agaccgtgat caatctggag
     7561 cgtcagggcg tggccttctc ccgtaccgag gacgggcata tcgcacagcg ccgattcggc
     7621 ggccatacgc gcgagttcgg tggagccccg gtcaagcgcg ccgcctatgc ggccgaccgt
     7681 atcggccacc agattctgca tgccttgtgg cagcagtgtg tggccgccgg cgttgagttt
     7741 gccgaggaat ggtatgtgac cgatctggcg ctcgccgatg atggcaagca ggcggccggt
     7801 attgtggctt ttgatacgca tacgggcaag attcaggcca ttcacgcgcg taatgtgctg
     7861 ctggccaccg gaggcgcggg ccgactgttc cacaccacgt cgaactcttg ggacttgacc
     7921 ggcgacggca tggcgctgac cctagctgcc ggcctgcagc ttgaagacat cgaattcgtg
     7981 cagttccacc ccaccggtct cgcacacacc ggcatcctgc tttccgaagc ggcacgcgcc
     8041 gagggcggca tcctgcgcaa tgccgacggc gagccgttca tggaacgtta tgctccagag
     8101 cataaggatc tggccgcgcg cgacgtggtc tcccgctcca tcatggcgga gatcgacgcc
     8161 ggccgcggcg ttgccgaccc gaaggatccg gatggtccga aggactgcgt ctggctggac
     8221 atgaccgaca tcgaccctga acgtatgaag gaagtgctgc cgcaggtggt cgaaaccatc
     8281 gaacagtacg cgaacctcga tccggccaaa gacctggtgc ccatcaagcc caccgcgcac
     8341 tatacgatgg gcggcatccc catcaccacc aatggcgagg tgtaccgttg gacggacgat
     8401 gccgtgcaaa tcgtcgatgg cttgttcgcc gctggcgaat gctcctgcgt ttccgtacac
     8461 ggcgcgaatc gcttgggcgg caattcgctg cttgacgcat gtctgttcgg cacgcgcgcc
     8521 ggccaaacca tggccacgcg tatcgccgag aatccggtcg actcccccat ggccgatgat
     8581 tcggccgatg acatgttgac gacggccgcc gatcatgccg ccgaatcccg taagtccgaa
     8641 cttgacgagc tgctcgccgg ccaagccgat gatgtcgatg agggttccac ggccaatcct
     8701 tatcagctca tggcccaact tggatcagtg atggaacagg ctctggctgt acgctgcacc
     8761 gctcagacca tcgatacggc tctggcccag ctcaacagcg acatcaagcc ggtttccgat
     8821 atcttacggg cacatgacaa aaccgccgcc ttcaaccaag aggtcaccgc catctgggag
     8881 gtccggcatt tgattgagct ggccgaggcc atgttgcacg cttccgagtc tcgtcaggaa
     8941 tctcgtgggt ccctgcagcg tcttgatttc cccgaacgcg atgatgagca tttcctcgct
     9001 cactcgttgg tcgccgatgc cggcccggtg agcttcaagc cggtgcatat caccgactac
     9061 ccgcccaaga agcgtgaata ctaagccgcc cagggcttgt gacacaatag attgtcgaat
     9121 aatcggactg atatccacgg tttctggagg cagaacatgg ttgaggcgaa caacacgacg
     9181 gttaccctgc aggtgcatcg tttcacgccg cgccccgagc gcgccgaacg tgcacgcggc
     9241 ggcagcccgt tcgccaagaa aagctccccg ttcggtggcg gctcggattc agcggcacgc
     9301 cgccgcccgc gtggcaagca gtgggtgcag gaatacacca ttcccgcgcg tccatcggac
     9361 accgtgctcg actgtctgct gaccattaaa cgcaccatcg acccgacgct ggccttccgc
     9421 tattcatgcg gtcacggcat gtgcggctct gatgccgcag ccatcaacgg cacacccact
     9481 ctgctgtgta cggccaccgt ccgcgactgg gccaagcagc ctagtacagc tccggaagtc
     9541 gatgatgagg gattccgacg caccggcgac gaaaccgcta acgaacccga cgttcccgcc
     9601 gaaaacgtcg aaaacaacat cactgaaggt tctctgggtg ttatcgaact ggcttccttg
     9661 cctggattcc cgccgcaacg tgatctcatc gccgacatcg acccgatgct caaccagatt
     9721 cgtaaactca ccccgtatct tcaggctgat ggcgtgcttg ccaccaccgc cgaaggcaaa
     9781 gtggacgttt tcgaatacct gcagaacccc gaacagctcg ccaagtatga gacgctgagc
     9841 aattgcatcg cctgcggtgt gtgcgagggt gcctgcccgg tatacgccgg cggcgatgca
     9901 ttcgttggcc cggccgcatt gatctgggct tcccgcttca tcaacgattc acgtgatacc
     9961 aaggccatgg atcgcatgga tgccattgat accgctgacg gtgtggccgg atgccaatcg
    10021 gtgcgtgcct gctcccgcca ctgcccgcgc ggtatcgatg tgggcgagga aatgtggcag
    10081 atcgtggcca aagtccgcga gcgctgaatc attgccgggt agataccgga aagtcatagt
    10141 ctgagagaac gaatatcgaa ggaacggtta tggacagaac acagtacacg aatctcgcca
    10201 aggcatggga attcaccgaa gaacatgctc gcgaacttga atcgtccaca ctggctgatg
    10261 cccgtaccgc cgccgacgaa tccggacaac tgcaaggtcc agccgcacaa gcccgactcc
    10321 tgggcctgct ggtccgtttg accggaacct cctcggtaat cgccgtgggc accggctcct
    10381 tggtggagac tctgcaactc gcctatgcct tggacaacaa gggacagttg accgccgtcg
    10441 attccaccgc acagggcatc acactgattc gcaaggcgtt tgccgaactg caggacgaga
    10501 ccgctaccac gcttcgtgcg gtgaatgccc cggccagtgt gtttctgccc aggctcaatg
    10561 ccaatgatta cgatttgatt gtggtggccg gcgatgcgga gaattatgcc gccacattcg
    10621 cccaggcgtc ccgcctgcta cgtgatcatg gtgccatcgt attcacggac gcattggctt
    10681 tggatacgga gcagggcggt gtgatcaacc cggccgaccg cagcggcaag gccacggcca
    10741 tgcgcgagct catcactacc gtcgagcagg atgaggaatt tgaatccaca cttactccgg
    10801 atggtaccgg actgctcatc gcgtacaaga agtaatattt cttggcttcc ctcgacggag
    10861 gggagccaaa tgctctcagg caaccatact cgtggccacg tccacggctt cgtcggcatc
    10921 gtcagtcacg gtaaccagct tgggatctat cttcgaaatc atgccacgct cggcgaccgg
    10981 cccatccaac cagtcgaata gcccctgcca ataatccttg ccgtacaaca ccaccggaat
    11041 gttcgccacc ttgtgggtct gaaccagggt caacagctcg aacatctcat ccaacgtgcc
    11101 gaaccctccc gggcagacga tcacaccgga ggaatacttg acgaacatcg tcttcctgac
    11161 aaagaagtac cggaagctca tgccaaggtt cacccactgg ttcagcccct gttcaaacgg
    11221 aagttcgatg ccgagcccca ccgacttgcc gcccgccaat gccgctcccc tgttcgcggc
    11281 ttccataatg cccggcccgc caccagtgat gacggcgata ttgcgcttgg cgatctggct
    11341 gcccatgcga cgagccgcct tgtagtccga ttcggtgcgt tgtgtgcgcg cggagccgaa
    11401 aatcgatacc gcaggcccca gctcggcaag cgcaccgaag ccatccacga attcggattg
    11461 gatgcgcagc acacgccacg gatccatatg cagccaatcg gtatcctgat ccggcttgag
    11521 caggttcgcg gtggtgttgt ccgaaggaat catctggccg cgcagaatca ctgggcctcg
    11581 atgataggtg tcccccagcg gcgcggcgtc ctccaaatca accggattca tcggaatttg
    11641 tgcgacttga atgttggctt gttcttcggc aattgttccg acgttcggat tcccgtcaac
    11701 accggtgttt gtcggctgct ttataccgga tgcttttttg ccatcggcct tttgggattt
    11761 tttctgcttc ttcgccattt ggtacctcca tggggctcta gcagtatcct aggcagatta
    11821 acgacggaag tcgatttcaa cgctttccgt gccgtccgca agggtgatgg aatgctccgc
    11881 cagctcgtcg gaatgcgtat tgacgtcgga ctcggcgtca gcctcagcag ctgcaacggc
    11941 cgcagcctgt tcaaatcgct tggattggcg gctcaacaat acgccggaaa tcgcggcggc
    12001 gatcagcgag gccaccagca caccgaatcg ggcttcggcg gacagctcct ggttcgtata
    12061 ggccagagag gcgatgagga acgacaccgt aaaaccgatt ccacaggcga cggcagcggg
    12121 aatcatatcg cgaacgcgta gccccttggc catcttgagc cctccgacat gtgtggccag
    12181 ccaagcggtg acgatgatac ccaacggctt gccgaccacc agcgccacaa tcagggcgat
    12241 gaccagtggc gagagcagca acagcggact catggattca aaatgtacgc cggtggcgaa
    12301 caaggcgaaa atcggcaaag ccagcagagc ggaaaacggc ttgagcttgt ccgcatatcg
    12361 ttcggcgcgc ggtgagtatt caccgtgcat cacacgtgcc ggggtcagca aaccaaccaa
    12421 tacaccggcc aacgtgggat ggatgccggc ttcaaacatc atgatccagg caaggatgcc
    12481 gaccacgccc accgcgatcc atggcacttt cttaagacga accagatgtg cccataccac
    12541 ggcacacacg gcgatgccaa tgaaccagta ccaagcattg accgaggaga agaacaccgc
    12601 tatcaggatg atggccagca aatcgtcgac cgtggccaaa gtcatcagga atgcgcggat
    12661 cgaaccgggc agcgccttgg caaacagtgc gagcaccgcc aacgagaacg cgatatccgt
    12721 ggctgtgggc accgcccagc cgtgggacat ctcggcgaac gggatgctgc tgccagtggt
    12781 ggccaggatc aatgagccag gctcccccgg gccgaactgc gaaaacagtg cagtggtggc
    12841 cagaaacagg atgggcgggg tgatcatgcc cccaacggca cacagcatcg gcacagcggc
    12901 cgccttggga ttagcgagcg agccggtggt gagctcctgc ttcagttcga ggccaacagt
    12961 caggaagaag atagtgagca aaccgtcctg agcccaatgg ccgatcggca gatcaagatt
    13021 ggtatgcgga atgaacacat gcgtttccgc tacggcctca aatgcatgcg cggtgagggg
    13081 aagattcgcc agaaccagac cggcaagggc aaaaccgagc ataatcagtc cagatatgcg
    13141 atcagaggcg gctatccgcc tgatcatggg ccaaatgcct cgttttgcgc cggtggttgt
    13201 ggccatcgcg tctcctcgct cgataatgaa tgatctgctg ctatggtacg gaatatctca
    13261 ggacgttcag cccggggcgt acccccccta ctgacggtca gccagagcgg tctcgatgtt
    13321 ggcaagcacc tgttcaagca gcctggtcgg acaggcaagg ttgacacgct cgaagaagtt
    13381 tccagattcg ccgaacatcg agccttcatc aaaccacaca cgggcctcat tgcgcagaaa
    13441 atcgcaaagt tcttcaggag tatcgaagcc caggcctcgg caatcgagcc aagccaagta
    13501 agtgccttcc ggttcaatca gacgaatgcc gcttacacgt gcagtgaagt cgcggatgag
    13561 cccgagattg cgttccagca cttccatcag tgcgtccagc cacggttcgg catggttgta
    13621 ggcggcttgg catgcgacca taccgaaatg gttgacggtc aggccgccga tattatccgc
    13681 cgccgcatcg taacgacgct tgagatgcgg gttcgggatg atggtgttgg agcacaacag
    13741 accagccaga ttgaaggttt tggtaggcgc ggtgaattca aagacgatat tcgcgtactc
    13801 agcccccaac gtggagaaca tggtgacctt atgtccagga taggaaaagt cggcgtgaat
    13861 ctcgtcgcac agcagacgca cacggcgttt gatacagata tcgccaatgc gccgcagttc
    13921 ttcaggcgtc cagacacggc ccaccgggtt gtgcggattg cacagaatca tggccgtgca
    13981 gcgaggatcg gcggccttgg attcgagatc atcaaaatca atgccatagt ggccgttctc
    14041 gtccagtacc agctcgttgt cgagaatggt caaaccattg tgctcggcgg caaaggtgaa
    14101 cgggtaatag acaggccgct ggataatgac cttatctccc ggtcgggtga cggatcgcag
    14161 ggccgtgttg acggcaggca tcacgccgtc ggacaggctc acccatgaag ggtcgatatg
    14221 gaaattatga cgatgctcca tccaattgag aaaagctgtg aagtagtctt cagtggcgta
    14281 atcgtaaccg aatacgtcat gggtggcaga ttggatgaga gcctcgacta cttcaggagc
    14341 cggtttgaat tccatgtctg ccacggacaa gggcaccaca tctttgccgt cctcacccat
    14401 ctgttccacg acctcatgcc atttggcgga cgaagagcca tgacgctcaa gaatcgtatc
    14461 gaaatcgtaa ggggcatgct gtgccagaat cactgtttct ccttcttcac taccggcgaa
    14521 aacaaacctg acccatcgta aaggaggtat gtaacgagaa ttggaaaagc ctcgaaggca
    14581 tttcgcttcc gaggctttat cgtgcgccag acaggattcg aacctgcgac ctgctgatcc
    14641 gtagtcagct gctctaatcc gctg
//
