LOCUS       gnlProkkaJOKINOCI_8    28886 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JOKINOCI_8.
ACCESSION   gnlProkkaJOKINOCI_8
VERSION     gnlProkkaJOKINOCI_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 06:47:39
            Original ID  :: gnl|Prokka|JOKINOCI_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 28886
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..28886
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..28886
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     protocluster    1..22765
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:2765]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2765
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..22765
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             complement(3..2765)
                     /NRPS_PKS="Domain: AMP-binding (233-630). E-value:
                     4.7e-106. Score: 346.6. Matches aSDomain:
                     nrpspksdomains_ctg8_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (737-806). E-value: 1e-25. Score:
                     81.6. Matches aSDomain: nrpspksdomains_ctg8_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     313.2; E-value: 4.1e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="AMP-binding (E-value: 6.7e-116, bitscore:
                     378.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.5e-18, bitscore:
                     56.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.6e-16, bitscore:
                     49.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQSIKGDKDSIGELKSEEHFLKSLTYKLPQQLSDKLNIFCNGSD
                     ERLHVVFTAALTLLINQYTERQNIVIKTPVFRKNRTIDSEQEILTLENTVHSEDLLKEI
                     IHKVGLTLEQALESSEANDKITGLPFDVIIILENIQEYILNQENSTNRILFSFMNQKQY
                     IETVIHYNECLYSQNMIKDMSLRFQMILEAMITPENIKVKDISFLDEKNKQKKIIGRED
                     NYSKIGTIAEVFEQQADEYSDKTALILDSSSMCYAELNHRANQLARYLQECGVRRGDLI
                     GIALERSFDLYISILAILKSGGAYVPLDPQYPKQRLSFLIEDSGVEFLITNESIQSQLP
                     SHGGGVICLDGKKEQIEKMDGSNIGIKGSLDDLAYVMYTSGSTGLPKGVSIVNRGVIRL
                     VKETDYAEFDENQKFLQLASAAFDASTFEIWGCLLNGGCLAIMPPGIPTAEDIAEAVKK
                     YNITTLWLTAGLFSLVVDQQLESLKGLQQLLVGGDVVSVPHVQKVLTLGTVQVINGYGP
                     TEGTTFTCCFPVPHDWKGSTLPIGRPISGTEIFILDSQLKPVAPGIPGELFIGGDGLAR
                     EYWRRPDLTKERFISHPFNNDPSARLYKTGDLVRYLENGDVEFIGRRDEQVKIRGFRIE
                     LGEIEARLINHTEIKEAAVTVNHNGDDDLYICAYYTSNHKIAKNELQHFLRDFLPEYMI
                     PSYFKQMDNMPLTVNGKIDRRALPRPDISQMSETKYEAPTNETEKKLSEIWEAVLGRER
                     VGIDENFFDTGGHSLKASMLISRIRKTFGTDIKVKELFEQPTIKQLSRLIQKRDKQNYP
                     VIGQAREKAYYQASSAQKRMFALWETDKDSIVYNLPIMIELNGKLDVKKAESVLQDILG
                     RHEALRTSFDVVNGDVVQIIHDTWELEFDYQKLPSDGLRTYVKQFIRPFH"
     CDS_motif       complement(126..236)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0006"
                     /evalue="3.90E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg8_1"
                     /protein_end="880"
                     /protein_start="843"
                     /score="35.4"
                     /tool="antismash"
                     /translation="VYNLPIMIELNGKLDVKKAESVLQDILGRHEALRTSF"
     aSDomain        complement(348..554)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_1_PCP.1"
                     /evalue="1.00E-25"
                     /label="ctg8_1_PCP.1"
                     /locus_tag="ctg8_1"
                     /protein_end="806"
                     /protein_start="737"
                     /score="81.6"
                     /tool="antismash"
                     /translation="EKKLSEIWEAVLGRERVGIDENFFDTGGHSLKASMLISRIRKTFG
                     TDIKVKELFEQPTIKQLSRLIQKR"
     aSModule        complement(348..2066)
                     /complete
                     /domains="nrpspksdomains_ctg8_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg8_1_PCP.1"
                     /locus_tags="ctg8_1"
                     /monomer_pairings="Val -> Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(846..911)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0005"
                     /evalue="4.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg8_1"
                     /protein_end="640"
                     /protein_start="618"
                     /score="37.9"
                     /tool="antismash"
                     /translation="FIGRRDEQVKIRGFRIELGEIE"
     aSDomain        complement(876..2066)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_1_AMP-binding.1"
                     /evalue="4.70E-106"
                     /label="ctg8_1_AMP-binding.1"
                     /locus_tag="ctg8_1"
                     /protein_end="630"
                     /protein_start="233"
                     /score="346.6"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEQQADEYSDKTALILDSSSMCYAELNHRANQLARYLQECGVRRG
                     DLIGIALERSFDLYISILAILKSGGAYVPLDPQYPKQRLSFLIEDSGVEFLITNESIQS
                     QLPSHGGGVICLDGKKEQIEKMDGSNIGIKGSLDDLAYVMYTSGSTGLPKGVSIVNRGV
                     IRLVKETDYAEFDENQKFLQLASAAFDASTFEIWGCLLNGGCLAIMPPGIPTAEDIAEA
                     VKKYNITTLWLTAGLFSLVVDQQLESLKGLQQLLVGGDVVSVPHVQKVLTLGTVQVING
                     YGPTEGTTFTCCFPVPHDWKGSTLPIGRPISGTEIFILDSQLKPVAPGIPGELFIGGDG
                     LAREYWRRPDLTKERFISHPFNNDPSARLYKTGDLVRYLENGDVEFIGRRDEQVKIR"
     CDS_motif       complement(999..1085)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0004"
                     /evalue="4.10E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg8_1"
                     /protein_end="589"
                     /protein_start="560"
                     /score="47.8"
                     /tool="antismash"
                     /translation="PGIPGELFIGGDGLAREYWRRPDLTKERF"
     CDS_motif       complement(1452..1478)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0003"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg8_1"
                     /protein_end="438"
                     /protein_start="429"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="WGCLLNGGC"
     CDS_motif       complement(1593..1646)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0002"
                     /evalue="4.80E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg8_1"
                     /protein_end="391"
                     /protein_start="373"
                     /score="25.3"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGLPKGVSI"
     CDS_motif       complement(1839..1880)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0001"
                     /evalue="5.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg8_1"
                     /protein_end="309"
                     /protein_start="295"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LAILKSGGAYVPLD"
     CDS             complement(3136..3831)
                     /NRPS_PKS="Domain: Thioesterase (2-227). E-value: 2.4e-38.
                     Score: 124.7. Matches aSDomain:
                     nrpspksdomains_ctg8_2_Thioesterase.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 222.5; E-value: 7.2e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MKKIFCLPYAGGSSAIYYKWRKLMSNSLTIHPIELKGRGTRINED
                     FYEHIDEAVNDIYDLIKDQIRECDYALFGHSMGGRLVYKLYCKIAEMQHRKPNHIFFSG
                     CGIPRTKKAESMIHALPDNLFLQRIMDMGGTSEELLHNKELQQLYLPILRSDFKMLEED
                     TNSGNKTVMDCDITVLHGIDDKTISSDLICNWKHYTLRKCNFYSFEGNHFFIHQFSNEI
                     TDIINKTLK"
     aSDomain        complement(3151..3825)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_2_Thioesterase.1"
                     /evalue="2.40E-38"
                     /label="ctg8_2_Thioesterase.1"
                     /locus_tag="ctg8_2"
                     /protein_end="227"
                     /protein_start="2"
                     /score="124.7"
                     /tool="antismash"
                     /translation="KIFCLPYAGGSSAIYYKWRKLMSNSLTIHPIELKGRGTRINEDFY
                     EHIDEAVNDIYDLIKDQIRECDYALFGHSMGGRLVYKLYCKIAEMQHRKPNHIFFSGCG
                     IPRTKKAESMIHALPDNLFLQRIMDMGGTSEELLHNKELQQLYLPILRSDFKMLEEDTN
                     SGNKTVMDCDITVLHGIDDKTISSDLICNWKHYTLRKCNFYSFEGNHFFIHQFSNEITD
                     IIN"
     CDS_motif       complement(3583..3624)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_2_0001"
                     /evalue="3.60E-04"
                     /label="NRPS-te1"
                     /locus_tag="ctg8_2"
                     /protein_end="83"
                     /protein_start="69"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YALFGHSMGGRLVY"
     CDS             complement(3905..4084)
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="MGMEELFGMAELIIGVLMNVFIGKIGQVAFGKDNRTTRIILRVIG
                     IFLIINGVSRAFHI"
     CDS             complement(4136..5302)
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MQLIAMIKHQLKLMLRNRLAIFATISVPLILTFLFSFSQDTDSKE
                     NLYIANADKSNYSAKLIEMIKEHKNIRVIKLKENELKKKVDDQDIPFGVVIEKGFGKDL
                     ADNHKIKMKIIQNYENGSGTLLEQLVSNEAGTLEKVVKDSQYMSSQLHTDSKDIEKNVF
                     KKLKNNSGIEVNDKTLSQGEHTQDNATVRLIGFLVMFIWFVVIQGLRTLIDEKENNTFN
                     RLLSTPVNYTKYVLSKMAATYISGIIHIIVIILAGKYLLKISIGHNIFAIAVILAVYLF
                     ALTCITMIMVPFMRSQKQFTSAASIIIAVSGMIGGSFFSLEIAPKYMQVISKFTPEAWA
                     IQSLNNIIFSKSTIGTEWLPIVIFTGVGLLSIIVSFFLINREIKKKKN"
     CDS             complement(5305..6513)
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MRKLFNLFFLDFKLLTKNKSFYLKLMLFPSLLILILGSVFSNSDS
                     KIEAFDVAFYSADSGENVSLGDVLKDKVFKKGDLKDIIHLKEAESYNEGEKLVKEGKAA
                     AFIYVPEHFTKAVMHNGKTNIDLIGDNNKTIDKNIVQAVLEGFTKSVKTMSAEQQEVLK
                     HINPDGSIPKEKIEKMMNDLADNDGISADIPKTATNKNAVPVDSMQYYSIAMVVMFSIM
                     TAFVLVHSIVDERQNNTLFRIKSTPTLNIQYVLGKLTGIIFAILMQMAAVILISWVVFR
                     MNWGNLFDIFVITVVYAFAIGSIVLFWGFTAKDHVAVSSMASPVLYIFSFLGGSFISKN
                     GLPDSLRVVQEIIPNGKAINSYLKVKQNIGLSGMYIDLLELIGIGLIFVFINIMVYNRK
                     KVA"
     protocluster    6268..28886
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[16267:18886]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      16268..18886
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     cand_cluster    6268..28886
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             complement(6529..7461)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 209.3; E-value:
                     1.1e-63)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MLELKKLTKKYDDFTAVNNISLTVEDGEVFGLLGPNGAGKSTMVS
                     MISTVLAPTSGTIKVDNKSLKEKPIEIKKIMGVVPQDLALYETLSAKDNLNFFGSLYGL
                     SGKKLKERTDEVLEIIELTDKKNQNVSEFSGGMKRRVNIGVALMNNPKILILDEPTVGI
                     DPQSRNHILETVKRLNKEKGMTVIYTSHYMEEVEYLCEKVAIVDHGSLIALGTKEELKE
                     SLNACDTLTVTFKDADEEALRRINSITGIDKVTVDHKQISMLVSTKERNIIEIVDDIKN
                     LGIDLTSFKYEEVNLESIFLQITGKNLRD"
     CDS             complement(7681..8334)
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 174; E-value:
                     4e-53)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MDIIIVDDQQIVREGLKMILSLHEEINIVGEASNGEHLLDLLKHT
                     RPEIILMDIRMPIMDGIEATKLVKERYPDIKVIILTTFNDSEYIFTGLKSGADGYILKD
                     SDSQEIIDSIKTACEGNILLNPKVTLKVVKALNSVEHNKELIQENNEKEQMLQLLTPRE
                     KEVAKQIMEGKSNKAISEALFITEGTVKNYVSRILEKLQVNNRTELSLYLQKHM"
     CDS             complement(8357..9505)
                     /gene_functions="regulatory (smcogs) SMCOG1048:sensor
                     histidine kinase (Score: 148; E-value: 7.1e-45)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MKNLSSLSTRVLIEKTIICFSLYSIIISILKTSVSEFVCLLIITI
                     FLVVNDHIRLKYLSGHYSFRYYASFLLSNLLSGILLFKINCLGSQIYNIFLLIEIIVTT
                     RKLPWTVVSLHFIIFFTALKAAGNSGKDILMSYLVIMAIIYLFRNVLLEKAKIQTLNKE
                     LQSANTKLKNYSQKIQELTISKERTRIAQELHDSLGHYLIALTMNLEFADKIVSKNPSE
                     AKQVINKSHDLSKECIINLRKAVALLNDPAPQKGLLKSINEIFENFQQTNEIKFELDMD
                     NKVESADPDIKNCLYKTVQESITNGIKHGNATFFSIRIRMSFEQISISITDNGTGCSEI
                     NKSNGIKGIEKRFAALGGEVNFHSGMDSGFTVEAVIPEMADL"
     CDS             complement(9561..10265)
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MSHYRTLLFDIDNTLLDFTASETDALQKLFQGSKLDLTAEVEARY
                     KALNQGLWKAFEEGEMTRDEVVNTRFALLFKEYGLEADGVLMNQTYRQYLEEGHQMIDG
                     AYELIERLSPLFDLYIVTNGVSRSQYKRLGDSGLYPFFKDVFVSEDTGFQKPMKEYFDY
                     VFARIPGFSAEHGLIIGDSLSADIKGGQMAGIDTCWFNPGKKANESGIIPTYEIQSLDE
                     LYDVLNVEVVAL"
     CDS             complement(10358..11743)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 430.3;
                     E-value: 1.1e-130)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MANKELKRGLGARHIQMIALGGTIGVGLFMGSSSTIEWTGPSVLL
                     AYAISGIFIFFIMRAMGEMLYVEPSTGSFATFGHKYIHPLAGYMTAWSNWFQWVIVGMS
                     EIIAVGSYMKYWFPDLPAWIPGIIAMAILGAANLISVKSFGEFEFWFAMIKIVTIILMI
                     VAGIGIIFFGFGNGGHAIGLSNLWSHGGFFTNGFSGFFFALSLVIAAYQGVELIGITAG
                     EAKDPQKTLRSAIQSIIWRILIFYIGAIFVIVTVYPWNELHSLGSPFVSTFAKVGITAA
                     AGLINFVVITAAMSGCNSGIFSAGRMLYTLGVNGQAPKFFKKVSSSGVPIFGTLAVLIG
                     LVIGVVLNYIAPPKIFVYVYSASVLPGMIPWFVILISHLGFRRAKGAELDKHPFKMPFA
                     PVTNYLTIAFLLMVLVGMWFNKDTRISLVVGVIFLAIVTVSYYAFGIGKRMPDEESKIE
                     DAV"
     CDS             complement(12168..12599)
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 80.2; E-value: 1.8e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MSKQDPIELIEYELTTFIRRAVYLDNSDRKIGNLERASYLLLRQL
                     DEFGPARVKELAESFKLDISTLSRQAAALEAKELIQRLSDPSDGRVSLFAITKLGRQRL
                     KADKKMRLDRYERMLDDWSGDEKEMFGRLLLRLNEAFID"
     CDS             12796..13200
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MKVIRIILQIIILFAFSFIGGAIQQFCHLPIPGSIIGLILLIICL
                     SIKIIPVKMIEDGAGFLLSFLPLLFIPAMTGVINYPSLFSASGAALFLIVVLSTLVTMI
                     AAGYASQLLEHKANQRKEKKKCSKHVSQSL"
     CDS             13170..13862
                     /locus_tag="ctg8_13"
                     /transl_table=11
                     /translation="MQQTCIAILIILFTAAAYLAMVKLYVRFPYPFLIPVLTTTIFIIA
                     VLLVFHISYKEYMIGGQWINSLLGPAVVALAYPLYKQRRVLIKYMFPIIGGVLAGLFSG
                     MVSGLLFAELFGISRSLILSIIPKSITTPVAIQIASGIGGVPSMTVVFVMIAGFSGVIL
                     GPMLLKWIRIRSSLGKGIAFGSASHALGTSKAMEYGELTVSMSSVSMTLCAVLGSVFGP
                     VVAWMFQI"
     CDS             13976..14818
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     189.3; E-value: 1.5e-57)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_14"
                     /transl_table=11
                     /translation="MIAAIPQKKLLDGTSIPAIGFGTYALNGNNGVHAVNSAIDIGYRL
                     IDTAYNYENEGAVGEAIRRSSVPREQLYVTSKLPGRYHEYDKAVQTIQESLYRAGLDYY
                     DLYLVHWPNPKQDRYLEAWQALIDAKKWGLIRSIGVCNFLPEHIERLERETGVKPSINQ
                     IELHPAFNQQQQRQWHEEQGIVTESWSPLSRAGEVLNDQKLGQIADKYGKTISQVILRW
                     HIQLGAIPIPKSASPERQLENISVFDFSLDENDMKIIDSLTRPDGRIKGQDPAEYEEF"
     CDS             complement(15061..15903)
                     /NRPS_PKS="Domain: oMT (70-171). E-value: 4.6e-09. Score:
                     26.6. Matches aSDomain: nrpspksdomains_ctg8_15_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 72.5; E-value:
                     6.2e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_15"
                     /transl_table=11
                     /translation="MTTIKKLLELAKNPEPFEEGTQEVWLDPDRAELVLKSHFDEYIPG
                     GSKGSSFIDETVDFITKIAPVECNNKIIDLGCGPGLYSQKLALKGYNVTGVDYNKKSID
                     YAISEADKMNLQIDYKIEDITNLEIENEFDAALLIYQIYGVFSPNNRRKILNNIYRGLK
                     PGGLVLLDVLSEKSYEKFEQNLMWFLSKKDSLISDKEHLTLYAAIKYPDNVTLAKNVLV
                     FDDGKLVNYNYWNQHFSIEDLEKEVNEAGFNLEKVYADVNGEEYENNREFFAAVLKKK"
     aSDomain        complement(15391..15693)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_15_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="4.60E-09"
                     /label="ctg8_15_oMT.1"
                     /locus_tag="ctg8_15"
                     /protein_end="171"
                     /protein_start="70"
                     /score="26.6"
                     /tool="antismash"
                     /translation="KIIDLGCGPGLYSQKLALKGYNVTGVDYNKKSIDYAISEADKMNL
                     QIDYKIEDITNLEIENEFDAALLIYQIYGVFSPNNRRKILNNIYRGLKPGGLVLLD"
     CDS             complement(16067..16237)
                     /gene="allorf_16067_16237"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_16067_16237"
                     /protein_id="allorf_16067_16237"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPINTRKEVRKVNDVLELQKLEKETDGKGIAVDATITTTWTVTTT
                     SGFVSSVSNHC"
     CDS_motif       complement(16142..16237)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MPINTRKEVRKVNDVLELQKLEKETDGKGIAV"
                     /locus_tag="allorf_16067_16237_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16067..16141)
                     /prepeptide="core"
                     /locus_tag="allorf_16067_16237_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="3.30"
                     /molecular_weight="2300.5"
                     /monoisotopic_mass="2299.2"
                     /core_sequence="DATITTTWTVTTTSGFVSSVSNHC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPINTRKEVRKVNDVLELQKLEKETDGKGIAV"
                     /leader_location="[16141:16237](-)"
                     /alternative_weights="2318.5"
                     /alternative_weights="2336.5"
                     /alternative_weights="2354.5"
                     /alternative_weights="2372.5"
                     /alternative_weights="2390.6"
                     /alternative_weights="2408.6"
                     /alternative_weights="2426.6"
                     /alternative_weights="2444.6"
                     /alternative_weights="2462.6"
                     /alternative_weights="2480.7"
                     /alternative_weights="2498.7"
     CDS             complement(16268..18886)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 77.8;
                     E-value: 1.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_16"
                     /sec_met_domain="micKC (E-value: 1.3e-145, bitscore: 477.9,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 6.7e-18, bitscore: 56.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.8e-18, bitscore:
                     57.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGNMLYHQYLKANSEYFGKQEMTMNTYEVNDIPDTYTVISDSNS
                     VWKYYHVKGVSLPEQGWKIHLTSLLEDAQSVLDRAARFCMDKKIEFKHLKDRHSFINMN
                     SKNANRASSGKFITVYPANEEIFVELLQDLSEITKDFKKGPYILSDKRWKNSNVFYRYG
                     GFKLIFNEHGEHCIRDESGNLIKDQRTPFYQIPDFVKDFDDYLNTINLSEDSEQQEESH
                     LAKYDIITALSYSNAGGVYLATRKKDNLKVIIKEARPNAGLDGGSRDALERQKIEYDTL
                     KKLKNIHGVVNLLEYFQEWEHHFLVEEFIEGRDLRQWIAQEYPFLRDEDDDDDSICNHA
                     KNIKKILLQLFALTDQMHINGVAMGDLQPANVMVTEDLTVKIIDFETAMPVESEEKPSM
                     ATIGFVSQEMKAGGSRDWFGLKRLVRYLTLPVLSSDDIDGYLQDNHLYWIKMNYGESFY
                     NFILELQKKCDDKIKSYHKYVPAEINLCNKKRDFNLNSMINKLIKGLENNLTDDEKLVN
                     GDIRQFEMSGGKFNFLTGGSGAAYILTRCNSKSKNVDNWIRNFLVDNLSIGDDGLLTGK
                     TGMLALLYERGHKEAVLNELNVLRNNVNETTNISLRSGLSGIGLFLISLYFETESKEYL
                     EFAKEIEKLIELNKVKEESLKVNDWMAVDIGLIDGLSGVSLFYSALYSATNNKKYLEEA
                     ELLLKKDLEKTKKDDVTGVLQTLDDRNRLLPYLSGGSIGVAVSIWFLNHVSGQDLFKEE
                     FRAILNLSKMRCTISGGLFDGAGSFLLIPSMVNNGCIRKRILMEVMNLLNIFLIEKNDY
                     YVYPGQFSYRLSDDVYTGSSGVVLALMGIVKSNPLYWLPLVNTDKFLVETKIKNIPVTI
                     N"
     CDS             complement(18953..19606)
                     /locus_tag="ctg8_17"
                     /transl_table=11
                     /translation="MRGLLLTNYYLVYRSFFAYTGLAILISAVIFYFGDASMHRFVAML
                     IILFVVMPALEVIKYESKSGYDKYVLTLPVSRTNIVQSHYFFYLLVVVIGAVISYGIFF
                     VYSLVFGEPVDGILNIVSFGTFIVLFAGAIVYPLLYIIGPEKSDAIVIGGAMGGLFTTF
                     GLQSVVGYVTEKLPLSFLHINPSLYVPIIYIIIGFIFYIISFFIAAAIYHKKEF"
     CDS             complement(19584..20459)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 154.5; E-value:
                     6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_18"
                     /transl_table=11
                     /translation="MMSNLLEIRNISKSFGHKAVLKNVTFNVPAGSIVGFIGDNGAGKS
                     TTFKTILGLISQDRGKVKIFGKENLDKHIKFKEDIGVVFDAMNLPAHLTIKQLNNVFKK
                     LFDAWDQDDFYRLVHSFSLPMDKKVNKFSRGMSMKLSVAVALSHNAKLLLLDEATGGLD
                     PSSRDDLLNELKSFVSKSNGGILLSSHIMSDVEKVASHIIIMKDGEILLNEEKDKVLER
                     YTVIDVDESQMAKLDEDIILVKRNYGTYWSVLVSDQQKLPNGVTAKTISIEEISVFLTR
                     SEKNERSVIN"
     CDS             complement(21118..22920)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_19"
                     /sec_met_domain="GATase_7 (E-value: 2.8e-16, bitscore:
                     51.1, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGHLDAKEILLKGLEKLEYRGYDSAGIAVANEQGVHVY
                     KEKGRIADLREVVDQTVESQAGIGHTRWATHGEPSFLNAHPHQSALGRFTLVHNGVIEN
                     YVQLKREYLENVELKSDTDTEVVVQMIEQFVAGGLSTEEAFRKTLTLLKGSYAIALFDG
                     ENTDTIYVAKNKSPLLIGLGDTFNVVASDAMAMLQVTNEYVELLDKEMVIVTKDEAVIK
                     NLDGEVMTRASYIAELDASDIEKGTYPHYMLKETDEQPLVMRKIIQTYQDENGRLAVAG
                     DVADAVAEADRIYIVACGTSYHAGLVGKQYIEMWANVPVEVHVASEFSYNMPLLSKKPL
                     FIFLSQSGETADSRAVLVQVKALGHKALTITNVPGSTLSREADYTLLLHAGPEIAVAST
                     KAYTAQIAVLAILASVAAERNGVDIGFDLVKELGIAANAMEALCDQKDEMEMIAREYLT
                     VSRNAFFIGRGLDYFVCVEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVFALAT
                     QEHVNLSIRGNVKEVAARGANTCIISLKGLEDADDRFILPEVNPALAPLVSVVPLQLIA
                     YYAALHRGCDVDKPRNLAKSVTVE"
     CDS             complement(23352..24698)
                     /locus_tag="ctg8_20"
                     /transl_table=11
                     /translation="MGKYFGTDGVRGVANSELTPELAFKVGRFGGYVLTKDKQRPKVLI
                     GRDTRISGHMLEGALVAGLLSIGAEVMRLGVISTPGVSYLTKAMDAEAGVMISASHNPV
                     QDNGIKFFGGDGFKLSDEQEAEIERLMDEPEDKLPRPTGADLGLVNDYFEGVQKYLQFL
                     KQTADEDFTGIHVALDCAHGATSSIATHLFADLDADVSTMGTSPNGLNINDGVGSTHPE
                     ALSAFVKEKNADIGLAFDGDGDRLIAVDEKGNIVDGDQIMYICAKYLKSEGRLKDDTVV
                     STVMSNLGFYKALEKEEIKSIQTAVGDRYVVEAMKKDGYNVGGEQSGHLIFLDYNTTGD
                     GLLSAIMLVNTLKASGKTLSELAGEMKKFPQLLVNVKVTDKYKVEENAKVKAVISEVEK
                     EMNGDGRILVRPSGTEPLVRVMAEARTKELCDEYVTKIVDVVRTEMGAE"
     CDS             complement(24716..26152)
                     /locus_tag="ctg8_21"
                     /transl_table=11
                     /translation="MDKFLNNRWAVKIIALLFALLLYVAVNNNQAPTPKKPGESFFPTS
                     TTDEATLTDIPVKAYYDEANYVVTGVPQTVNVTIKGSTSAVKKARQTKNFEIYADMNKL
                     KTGTHKVELKAKNVSDGLTISINPSVTTVTIQEKTAESFPVEVEYYNKSKMKKGYTPQQ
                     PIISPKNVQITGSKNVIDNISLVKASVNLENANETIDKEVKVTVYDKDGNALPVDVEPS
                     VIKVTVPVASPSKKLPFKIERKGSLPDGVSVASIDSNPSEVTVYGPQDVLDSLEFIDGV
                     SLDLDKIDKDTDVDADIPLPKGVTKVSPGKITLHVKVDSEDKKDFSNVPIKTVGLGGSQ
                     RIEFLDPESRAIDITAKGSPANIKALKKSDIELYANVSGLDDGEHSVKLEVNGPQNVTW
                     SLSKDTVKIRLTSKKNTSSNKNDGGSADSGNKDGTSGDADKDKNKNQEDTDSDQNKSQN
                     QDQNQDQDEDGSSADSSSTE"
     CDS             complement(26145..26966)
                     /locus_tag="ctg8_22"
                     /transl_table=11
                     /translation="MAFEDIPFLQYLGNAVDILLVWYVIYKLIMVIRGTKAVQLLKGIV
                     VIVLVRMASSYLGLSTLQWLMDQAITWGFLAIIIIFQPELRRALEQLGRGRFFSRSGTP
                     VEEAQHKTIEAITKSISYMAKRRIGALIAIERDTGMGDYIETGIPLNAQVSSELLINIF
                     IPNTPLHDGAVIMKNNEIAAAACYLPLSESPFISKELGTRHRAAVGISEVTDSLTIIVS
                     EETGAISVAKNGDLHRELTEEALKEMLEAEFKKNARDTSSNRWYWRGKKNG"
     CDS             complement(27132..27758)
                     /locus_tag="ctg8_23"
                     /transl_table=11
                     /translation="MSCPEQIVQLMHKHLDGDILPEDENVLKQHLRSCEDCKRHFHEME
                     KSVALVRSTSHVTAPADFTAKVMANLPKEKKRASVKRWIKTHPIIAAAAVFVILMGGGF
                     FNSWHNDHNFSVSKQPNLVVQNHTVTVPEGETVKGDVTVKNGKLVIKGKVDGNVTVVNG
                     EKYMASAGQVTGQIEEINQLFDWVWYELKSAGQGVVSALDPNEDE"
     CDS             complement(27772..28335)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 138.8;
                     E-value: 2.3e-42)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_24"
                     /transl_table=11
                     /translation="MENLIKKRIKQVKKGDQNAFAEIVDLYKDKIYQLCYRMLGNDHEA
                     EDIAQEAFIRAYVNIDSFDINRKFSTWLYRIATNLTIDRIRKKKPDYYLDAEVAGAEGL
                     TMYSQIAADGVLPEDAVLSLELSDTIQKKILKLPDKYRTVIVLKYIDELSLIEIGEILN
                     IPVGTVKTRIHRGREALRKQLRDL"
ORIGIN
        1 aaatgaaagg gcctgataaa ttgtttcaca tatgttcgta acccatcaga cggcagcttc
       61 tgataatcaa attcgagctc ccatgtatcg tgaataatct gaaccacatc gccgtttaca
      121 acatcgaaac ttgtccgtaa tgcttcgtgt ctgccaagaa tatcttgtaa aactgattca
      181 gcttttttta cgtctaattt tccgtttagt tcgatcataa tcggcaggtt ataaacgata
      241 ctgtctttat ccgtctccca aagggcaaac attcttttct gggccgatga tgcttgataa
      301 taagccttct ctctcgcttg accgatgact ggataattct gtttatcccg tttttgaatg
      361 agacggctca actgtttgat ggtaggctgc tcaaaaagct ccttcacctt tatatccgtg
      421 ccgaatgttt ttctgatgcg ggaaattaac atagaagcct ttaatgaatg accgccggta
      481 tcaaagaaat tttcatctat accgacacgt tccctgccaa gtacagcttc ccaaatctcc
      541 gaaagttttt tctccgtttc atttgtcggc gcttcatatt ttgtttcgga catttgagat
      601 atatcaggtc gaggaagtgc ccgtctgtca attttcccat ttaccgtcaa aggcatgtta
      661 tccatttgtt taaagtacga tggaatcata tattccggaa gaaagtctct aagaaagtgc
      721 tgcaattcat tctttgcgat tttatgattt gaagtgtaat aagcacagat atataaatca
      781 tcatcaccat tatgatttac tgttactgcc gcttctttaa tttctgtatg attgatcaat
      841 cgggcttcta tctccccaag ctcgattcta aaaccgcgga ttttgacttg ctcgtcccgc
      901 cgtccaataa actccacatc gccattttct aaataacgca ctaagtctcc tgttttataa
      961 agacgtgctg aaggatcatt attgaaaggg tgtgatataa accgttcctt cgttaaatca
     1021 ggccgtcgcc aatactctcg cgccagccca tctccgccaa taaacagctc accaggaata
     1081 ccaggcgcta ccggttttaa ttgcgaatct aaaatgaata tttctgtacc agaaataggc
     1141 ctccctatag gaagcgtact gcctttccaa tcatgaggga ccgggaaaca acaggtaaag
     1201 gtcgttccct ctgtcggccc atatccgtta attacttgta cagttccaag cgttaatact
     1261 ttttgtacat gcggaactga aaccacatct ccgcctacca ataattgctg aagccctttt
     1321 aatgattcta actgctgatc aactactaga gaaaataaac cggccgtcag ccaaagagtc
     1381 gtaatgttat atttttttac agcttctgca atatcctcag ccgtcggtat tcccggaggc
     1441 attatagcca gacatccccc attcaataaa cagccccaga tctcgaaggt agaagcgtca
     1501 aaagcagcag aagctaattg cagaaacttt tgattctcat caaactcagc ataatcagtc
     1561 tccttcacca gccgaatcac accgcggtta acaatgctta ctcctttagg caatcccgtt
     1621 gaacctgacg tatacatgac ataagccagg tcatccaagg aaccttttat gccaatatta
     1681 gatccgtcca tcttttcaat ctgttctttc ttaccatcca aacagattac gccgcccccg
     1741 tgagacggga gttgtgactg aatgctttcg tttgtaataa ggaactctac acctgaatcc
     1801 tcgattaaga atgatagtct ttgcttcgga tattgagggt ctaacggcac ataagcaccg
     1861 ccggatttta gtattgccag aatactaata tacaaatcaa aagagcgttc taaagcaatt
     1921 ccgataaggt ctccccgtct tactccgcac tcctgaagat accgtgccaa ctggttcgca
     1981 cggtgattaa gttctgcata acacattgaa gagctgtcta gtatcaaagc agtcttatcc
     2041 gaatattcat cagcctgctg ctcaaatacc tctgcaattg taccaatttt cgaataatta
     2101 tcttcccggc caatgatttt cttttgctta tttttttcat ccagaaagct tatatctttg
     2161 accttgatat tttcaggagt tatcatagcc tcaaggatca tctgaaatcg cagtgacata
     2221 tcttttatca tattttgaga gtataggcat tcattatagt gtatgactgt ctctatatat
     2281 tgtttctggt tcataaatga aaataggata cgattagtgg aattttcttg attaagtatg
     2341 tattcttgaa tattttcaag gattattatg acatcaaaag gaaggccagt tattttatca
     2401 ttagcttcag agctttccaa tgcctgttct agggttaatc cgactttatg tatgatctct
     2461 ttcaataggt cttcactgtg aacagtattt tcaagagtca aaatttcttg ctcagaatca
     2521 attgttctgt tctttctgaa aacaggagtt ttgattacaa tgttttgtct ttctgtatat
     2581 tgatttatta ataaagtcaa tgccgctgta aatacgacat gcagacgttc atccgatcca
     2641 ttgcagaata tattaagctt atcgcttaat tgctgtggca atttatatgt aagacttttc
     2701 aaaaaatgtt cttcactttt taactcacca atactgtctt tatctccctt tatactttgt
     2761 gtcataacaa aaactccttc acttgatatc aaaaattcat tcactgaatt aaacagcaga
     2821 ggcttcacgg tggatttttc agttaaactg cgtcacaggc cataccgctc accaataatt
     2881 gttgttgtaa tctgacagtt tatttatcgg caacaaaaac cattttttaa tgatatagac
     2941 ccgtacaatc acttttttta aaaaaaggat aatgaagaag aactagccat cttaaagaaa
     3001 tattatacaa atattcaaga gttgtcaatt agcaggaaaa aacacctaag catattaacc
     3061 cgatttttat tttccttatt aacataaaaa aaaatcggga caaagtaact ctcccgattt
     3121 tttcgagccg aaaatttatt tcaaggtttt atttataata tctgttattt cattcgaaaa
     3181 ttgatgaata aaaaagtgat ttccttcaaa cgaataaaaa ttgcatttcc ttaaagtata
     3241 atgtttccaa ttacatatta aatccgagct tatggtcttg tcatcaatac catgcaacac
     3301 tgttatatca caatccataa ctgtcttatt tccagagttg gtatcctctt ctaacatttt
     3361 gaaatcactt ctcaaaatag gaagatataa ttgttgtaat tccttgttat gtaacagttc
     3421 ttccgaagtt ccgcccatat ccatgattct ttgcaaaaat aaattatccg gcaaagcatg
     3481 aatcatactc tctgcttttt tcgttctggg aatgccgcac ccggagaaaa atatgtgatt
     3541 tggtttccta tgttgcattt cagcaatttt acaatacagc ttataaacta atcggcctcc
     3601 catgctgtgt ccgaataaag cataatcaca ctctctgatt tgatccttta tcagatcata
     3661 tatatcatta acagcctcat ctatgtgttc ataaaaatct tcgttaattc ttgtacctct
     3721 tccttttaat tcaataggat gtattgttaa agagttactc attaactttc tccatttata
     3781 gtatattgca cttgatcctc ccgcatacgg aagacaaaat atttttttca taattcacct
     3841 cagaaatttt gtaataaccc gataaaaaaa cacccttaaa aggatgtttt ttactatctc
     3901 agttttatat atgaaatgct cttgaaactc cgttgatgat aaggaagatt cctattactc
     3961 ttaaaatgat ccttgttgtt ctgttatctt ttccaaaagc aacttgcccg attttaccga
     4021 taaatacgtt catgagtaca cctataatta attcagccat tccaaatagt tcttccatac
     4081 ccaattccct cacgtccttt tataagctat gaatttcttc atttattgat gatcattaat
     4141 ttttcttttt cttaatttct ctgtttatta agaagaaaga tacaataata ctcaataagc
     4201 cgacacctgt aaaaataacg attggaagcc attcagttcc tattgtactc ttactaaaga
     4261 taatgttgtt taaagactgt attgcccatg cctcgggtgt aaatttagaa atgacctgca
     4321 tatatttagg agcgatttcc aatgagaaaa aggaaccgcc tatcatcccg cttactgcaa
     4381 ttataattga tgctgcagaa gtaaactgtt tttggcttct cataaacgga accataatca
     4441 tcgtaatgca ggtcaatgca aataaataaa cggccagtat aacagcgatg gcaaagatgt
     4501 tatgacctat actgatctta agcagatatt ttcctgcaag tataataacg ataatatgaa
     4561 tgattccaga aatataagta gcagccattt tggataaaac atattttgta tagtttacag
     4621 gcgtactcag taatctgttg aaagtattat tctctttttc atcaataagt gttcttaacc
     4681 cttgaataac tacaaaccaa ataaacatta caagaaaacc aattaatctc acggtcgcat
     4741 tgtcctgagt atgctcaccc tgacttaatg ttttgtcatt cacttctatt cctgaattgt
     4801 ttttcaattt cttaaaaacg ttcttttcta tatcttttga gtccgtatgc agctgtgaag
     4861 acatatattg cgaatcttta actacctttt caagagttcc cgcctcattt gaaaccagtt
     4921 gctctaacaa tgttccgctg ccgttctcgt agttttggat gattttcatt tttatcttgt
     4981 gattgtccgc caaatccttt ccaaaacctt tttcaataac gactccaaaa ggaatatcct
     5041 gatcatcgac ttttttcttt aattcatttt cctttagctt tataactcta atatttttat
     5101 gctcttttat catttcaatg agcttcgcag aatagttgct tttatcagca ttggctatat
     5161 acaagttctc tttgctatca gtatcttgag aaaaagaaaa caaaaatgta aggattaacg
     5221 gcaccgaaat agttgcaaaa attgctaatc tatttcggag catcagcttc agctgatgtt
     5281 taatcatggc aatcaattgc actactacgc caccttcttc ctgttgtata ccataatgtt
     5341 aataaagaca aagatgagac caataccaat aagctcaagc aagtcaatat acatgccgct
     5401 aaggccgata ttctgtttaa cttttaaata agagtttatt gccttaccgt tcgggatgat
     5461 ctcctgaaca accctcagac tatcagggag cccgttctta gaaatgaaac tgcctcctaa
     5521 aaaactgaaa atataaagaa ccggagaagc catactggac accgccacgt ggtctttggc
     5581 ggtaaaaccc caaaacaata caatgctgcc tatagcaaat gcgtatacta ccgtaataac
     5641 aaaaatatca aacaggttgc cccagttcat tcggaatacg acccagctga tcagaatcac
     5701 agcagccatc tgcattaaga tcgcaaaaat aatacctgtc aattttccga gcacatactg
     5761 aatatttaaa gtcggtgtag atttaatcct gaacagcgta ttattctgcc gctcatcaac
     5821 aatgctgtga acaagcacaa aagccgtcat aatggaaaac atgacaacca ttgcaattga
     5881 ataatactgc atggaatcga caggaaccgc attcttattt gtcgctgttt ttgggatgtc
     5941 agcagagatg ccgtcattat cggccagatc gttcatcatt ttttctattt tttcttttgg
     6001 tatgctgccg tcggggttga tatgttttaa tacttcttgt tgctcagcac tcattgtttt
     6061 cacgcttttc gtaaagccct ccaaaacagc ctgaacaata tttttatcta tcgtcttgtt
     6121 attgtctcca attaaatcga tatttgtttt cccgttgtgc atgacggctt tcgtaaagtg
     6181 ttccggtaca tagataaaag ccgctgcctt tccctcttta actaattttt cgccttcatt
     6241 gtagctctca gcttctttta aatgaatgat atctttcaga tcgcctttct taaaaacttt
     6301 atcctttaag acatcaccta aagaaacatt ctccccggaa tctgctgagt aaaaagctac
     6361 atcgaatgct tcgatctttg aatctgaatt actgaacaca ctgcccaata tgaggatcag
     6421 cagagatgga aacagcatca gttttaaata aaatgactta ttctttgtta acagcttaaa
     6481 atcaagaaaa aataagttga ataattttct caagatagcc tcctcctact aatctcttag
     6541 gtttttccct gtaatttgaa ggaaaatgct ttccaaattg acttcctcgt acttaaagct
     6601 tgtgaggtcg attcctaagt ttttgatatc atctacaatt tcaatgatgt ttctttcctt
     6661 cgttgataca agcattgaaa tttgtttatg atctacagtc actttatcaa ttcctgtaat
     6721 actgtttatc cgtcggagtg cctcttcatc agcatcctta aaagtaacag ttaaagtgtc
     6781 acaagcattt aagctttcct tgagttcttc tttcgttcct aaagcaataa gagatccatg
     6841 atcaacaatt gccaccttct cgcaaagata ctctacttct tccatgtagt ggctggtgta
     6901 aataacagtc attccttttt ctttattcag cctttttact gtttcaagaa tatgatttct
     6961 tgattgcgga tcgattccta ctgtaggctc atcaagaatt aatatttttg gattattcat
     7021 taacgccacg cctatgttaa cccgacgttt cattccccca gaaaactctg atacattttg
     7081 atttttttta tctgtcagtt caattatctc aagaacctca tcagttcttt cctttagctt
     7141 tttccctgac agcccgtaaa ggcttccgaa gaagtttaag ttatctttgg cgcttaacgt
     7201 ttcatataaa gctaaatcct gtggaacaac ccccattatt ttttttatct caataggttt
     7261 ttccttaagt gatttattgt ctactttaat tgtgccgctg gtaggtgcaa gaacagtact
     7321 aatcatagaa accattgttg atttgccggc accgttagga cccaatagtc cgaatacttc
     7381 tccatcttct acagtaagcg aaatattgtt aactgccgta aagtcatcat attttttggt
     7441 aagttttttt aattcgagca taattaaaac acccctcgtg gtatttcggt tcttttattt
     7501 taacctgaat ggaatatttt tagaatttac tatagtactc atttacttta ttactttagt
     7561 tatgaattac atcgttactt tagtcatata cggaaggtgt aagtccggat acattaagaa
     7621 gaaaatgaag gaaaggaatt tgatgaaatt cctttctggt taaggagaaa aaaagttgaa
     7681 tcacatgtgc ttttgtaaat ataagctcag ctccgttcgg ttgttcactt gaagtttttc
     7741 cagtattctg gatacataat ttttgactgt gccttcagta ataaacaatg cttcgcttat
     7801 agctttgttg ctcttccctt ccataatctg ttttgcgact tctttttctc tgggtgtaag
     7861 caattgcagc atctgttcct tttcattatt ttcttgaata agctctttat tatgttctac
     7921 cgagtttaaa gcttttacaa cttttagcgt tactttagga tttaacagaa tattgccttc
     7981 acatgctgtt ttgatggaat caataatttc ttgggaatca gaatctttca gtatgtaacc
     8041 atctgcaccg cttttcagtc cagtaaaaat gtattcgcta tcgttaaagg ttgtcagtat
     8101 aatcacttta atatccggat atctctcttt aactagcttt gttgcttcaa tgccgtccat
     8161 tatgggcatt cttatatcca ttaaaatgat ttcaggcctt gtatgtttta gcaaatctaa
     8221 taaatgttca ccattagaag cttcgcctac aatattaatt tcctcgtgaa ggctcagaat
     8281 cattttcagc ccctccctga caatttgctg atcatccaca ataataatat ccatatcata
     8341 cctcctgata ttcggattaa agatctgcca tctcgggaat tacggcttcc acagtaaatc
     8401 ctgaatccat ccctgaatga aaattaacct ctcctccaag tgcagcaaat cttttctcta
     8461 ttccttttat tccatttgac ttattaattt cagaacatcc tgtaccgttg tcagttatcg
     8521 atatagagat ttgttcaaaa gacatacgta ttcttattga aaaaaacgta gcatttccat
     8581 gttttattcc gttcgttata gactcttgta ctgttttata gagacaattc ttgatatcag
     8641 gatcagctga ctctacttta ttgtccatat caagctcgaa ttttatttca tttgtttgct
     8701 gaaaattttc aaaaatctca ttgatcgatt ttagaagccc tttttgagga gcagggtcat
     8761 tgagcaaagc gacagctttt ctcaggttaa taatacactc cttcgataaa tcatgtgact
     8821 tattgatgac ttgtttagcc tcgctcggat ttttactgac tattttatcg gcgaactcaa
     8881 gattcattgt taaggcgatc aaataatgcc ccagggaatc atgaagctct tgtgcaattc
     8941 ttgtccgctc tttagaaata gttaactctt gaatcttttg agaataattc ttaagttttg
     9001 tgtttgcact ttgtaattct ttatttaatg tttgtatttt tgctttttcg agcagtacgt
     9061 ttctaaacag ataaataata gccataatca ccaaataaga catcaatata tctttcccgc
     9121 tgttccccgc tgctttaaga gctgtaaaaa aaataatgaa atgcagactt actacagtcc
     9181 acggcagctt acgagttgtt acaataatct cgatcagtaa gaaaatatta tatatttgag
     9241 aaccgagaca gttaatttta aacaataaaa tgcctgacaa aaggttactt aataaaaagg
     9301 atgcataata tctaaaagaa taatgaccgc ttaggtattt taatctgata tgatcgttta
     9361 cgactaaaaa aatggtgata atcagcaggc aaacgaattc cgaaaccgac gttttaagaa
     9421 tagaaatgat aatagaatat aatgaaaagc aaataatggt tttctctatg agcactcttg
     9481 tactaagtga agaaagattt ttcataataa tcctttccgt cacaatctga tatgaattat
     9541 attatacata ttttgagaaa tcataaagcg acaacctcca cgttcagcac atcatacagc
     9601 tcatcaagcg attgaatctc atacgtcggg atgatcccgg actcatttgc tttcttcccg
     9661 ggattaaacc agcatgtatc aattcccgcc atctgaccgc cttttatgtc cgcgctcagt
     9721 gaatcgccga taataagccc gtgttcggca gaaaaaccgg gaattctcgc aaacacataa
     9781 tcaaagtatt ccttcatcgg cttttgaaaa cccgtatcct cagaaacaaa cacatcttta
     9841 aaaaacgggt acagacccga gtcgcccagc cgcttatact gtgatctcga caccccgttc
     9901 gtcacaatgt ataaatcaaa taaaggactc agcctttcaa tcagctcata agctccgtct
     9961 atcatctggt gcccttcttc taagtattgg cggtacgtct gattcatcag cacgccgtcc
    10021 gcttcgaggc cgtattcttt aaacaaaagg gcaaaccttg tattcaccac ttcatctcgg
    10081 gtcatttcac cctcttcaaa cgccttccac agcccttgat ttaacgcttt ataacgggct
    10141 tccacctctg ccgtcaggtc cagctttgaa ccttgaaaca atttttgaag agcatcggtt
    10201 tctgaagcgg taaaatccag cagcgtattg tctatatcaa ataataacgt acggtagtga
    10261 ctcatcgatg tttcccccgg ttctgctttt tttatccagt ataccactcg ctgacaagcc
    10321 gaaaaagaca cccctttaag agaggtgtct ttttgagtta tacagcgtct tctattttcg
    10381 attcttcatc aggcatgcgc ttgccgatac cgaacgcata atagctgacc gtcacaatcg
    10441 ccagaaaaat caccccgacg accaaagata tccgcgtatc tttgttaaac cacatgccga
    10501 ccagcaccat caataagaaa gcgatcgtca aatagtttgt cactggcgca aaaggcattt
    10561 taaacgggtg cttatcaagc tcagcgccct tcgctcttct gaaaccgaga tggctgatta
    10621 aaatgacgaa ccacgggatc attcccggaa gcacactcgc gctgtagaca tagacaaaaa
    10681 ttttcggagg cgcgatgtag ttcagcacga caccgatcac aagtccgatt aatactgcaa
    10741 gcgtaccgaa tatcggcaca ccgctcgaag aaactttctt aaaaaatttc ggcgcctgac
    10801 cgttcacgcc caatgtataa agcatgcgtc ccgcgctgaa aatcccgctg ttgcagccgg
    10861 acatcgcagc ggtaatcaca acaaagttaa tcaagccggc cgccgccgta atcccgactt
    10921 tcgcaaatgt cgaaacaaac ggactgccga gtgagtgaag ctcattccac ggatatacgg
    10981 tgacgataac gaaaatcgca ccgatgtaga aaattaaaat ccgccagata atgctctgaa
    11041 tcgcgcttcg cagcgttttt tgcgggtcct tcgcttcccc agccgtaatc ccgatcagtt
    11101 cgaccccttg ataggccgca atgaccagtg acaacgcaaa gaaaaatcct gaaaacccat
    11161 ttgtaaagaa accgccgtgc gaccataaat tagatagtcc gatcgcatga ccgccgttac
    11221 cgaaaccgaa gaaaataatc ccgattccgg caacaatcat cagaataatg gttacgattt
    11281 tgatcatggc aaaccaaaat tcaaactcac cgaaagattt taccgaaatc aaattcgccg
    11341 caccgagaat ggccatggcg ataatgccgg gaatccatgc cggcagatca ggaaaccaat
    11401 atttcatata cgaaccgacg gcgataattt cagacatccc gacgatcacc cattgaaacc
    11461 agttgctcca cgccgtcata tagccggcta acggatgtat atacttatgg ccgaatgtcg
    11521 caaacgatcc tgtactcggc tctacataga gcatttcgcc cattgcacgc atgataaaaa
    11581 agataaagat accggagatc gcataagcaa gcagaacgga cggcccggtc cattcaatcg
    11641 tgctggatga ccccatgaat aaaccgacac cgatcgtgcc gcccagcgca atcatctgga
    11701 tatgacgcgc gcctaagcct ctctttaatt ctttgtttgc cacttcgctt cctcctctta
    11761 acagctcaga tatatgtgaa ataatgaagc agaaggtgca cctgtttgaa cctaactcaa
    11821 tcttcatttc ccgcaatatt agaaatattc tatcttccta ttgttatata atctctaatt
    11881 tccttatctc atcataataa attttcgtgg aaaatacaat tgtttttttc aggtaaacac
    11941 cttacaccct aaaccagaat actaaaatta aagcgctttc attttagtaa attatgaata
    12001 ttatgataac aaaaactgca atctccgaga aacagtattt cccgggataa atgttttcca
    12061 ccccccattc tataaaattt ttgctaaagc agaatggcgt aaagccttct ctcttccatt
    12121 ctccttcata tacgccataa tcctgcttaa ccgggaaaaa ttattcacta atcgataaat
    12181 gcctcattca gccgcagcaa aagcctgccg aacatttctt tttcatcgcc ggaccaatca
    12241 tcaagcatgc gttcatatcg atcaagacgc atctttttat cagcttttaa cctctgcctg
    12301 ccaagcttcg taatcgcaaa aagactgacc cgcccgtcgg aaggatcgga taaacgctgg
    12361 atcagctcct tcgcctctaa ggccgcggct tggcgcgaca atgtagaaat atcaagctta
    12421 aaagattcgg ccaattcctt cacacgcgcc ggcccgaatt catccagctg ccgtaataac
    12481 aaatacgagg ccctttctag atttccgatt ttgcggtcgg agttatcaag ataaacagcc
    12541 ctcctgataa aagtggtaag ctcatattca attaattcaa tcggatcttg ttttgacaaa
    12601 cggcttcact ccttacaatt gacatcagaa atattagttg tataatacaa acatatgcac
    12661 atttactcag aaaacatata gaaaattttt gcatacatat atttgtatag tacaaatata
    12721 tgcaccaaaa gtaaagaaac ttaccgaagc aacaagaaag ggggaagctg ctcttctcca
    12781 aagaacagca tcgtcgtgaa agtcatacgc atcatattgc aaatcattat tttattcgca
    12841 ttttccttta tcgggggagc cattcagcag ttctgtcatc tgcccattcc cggcagcatc
    12901 atcggtttga tcctgctcat catatgttta tcgattaaga tcatccctgt caaaatgatt
    12961 gaagacggag ccggattttt gctgtctttt cttccgctgt tattcattcc ggccatgacg
    13021 ggggtcatca attatccgtc actgttttcc gcaagcggag cggccctgtt tttgatcgtc
    13081 gtgctgagca ctctcgtcac aatgatcgcc gcagggtacg ccagccaact gttagagcac
    13141 aaagccaatc agagaaagga gaaaaagaag tgcagcaaac atgtatcgca atccttataa
    13201 ttttgttcac ggccgccgcc tatctggcta tggtgaaatt atatgtgcgc tttccatatc
    13261 cctttctcat acccgttctg acgactacga ttttcataat cgctgtgctg cttgtttttc
    13321 atatttcgta taaagagtat atgatcggcg gacaatggat caattcactg ctcggcccgg
    13381 ccgtggtggc tttggcatac ccgctttata agcagcgccg tgtgttaatc aagtatatgt
    13441 ttccgatcat cggcggcgtg ctggccggtt tattctctgg aatggtcagc ggcctgttat
    13501 ttgcagagct gttcggcatc agccggagtt tgattttgtc aatcattcca aaatcaatca
    13561 cgactccggt cgccattcaa atcgcgtccg gtatcggcgg tgtcccttcc atgacagtcg
    13621 tgttcgtcat gatcgcgggg ttttccggcg tcatcttagg tccgatgctt ctcaagtgga
    13681 tccgcatccg cagttcactt gggaaaggaa tcgcattcgg gagcgcttca catgcgctcg
    13741 gcacctcaaa agcaatggaa tacggagaat taacggtctc catgagttct gtttccatga
    13801 cgctctgcgc cgtgttaggg tcggtcttcg gccccgtcgt tgcatggatg tttcaaattt
    13861 aaagctggcg gttctccgcc agcttttttc atgtgcagat catctcattt ccttccatta
    13921 ttatgtttca tttgtaagag taatggtaaa gtagaaatca aggagggatt taaagatgat
    13981 tgcagcaatt ccgcaaaaga aactgctgga tgggacaagc attcccgcga tcggcttcgg
    14041 tacatatgct cttaatggga acaacggcgt tcatgccgtc aacagcgcca ttgatatcgg
    14101 ctaccgcctg attgacacag cttataacta tgaaaatgaa ggggcggtcg gagaagccat
    14161 ccgcagaagc tctgttccga gagaacagtt atacgtgacg tccaaacttc cggggcgcta
    14221 ccatgaatat gacaaagcgg tacagacaat ccaagaatct ttataccgcg ccggtctgga
    14281 ttactatgac ctgtatcttg tccattggcc gaatccgaaa caagaccgct atctggaagc
    14341 atggcaggca ctgattgatg cgaaaaaatg gggcctgatc cgttccatcg gcgtctgcaa
    14401 tttcctgcct gaacacattg aacggctcga acgtgaaacc ggcgtaaagc caagcattaa
    14461 ccaaattgaa ttacatcccg cttttaatca gcagcagcag cgtcaatggc atgaggaaca
    14521 gggcatcgtg acagaatcat ggagcccgtt atcccgcgcc ggagaagtat tgaacgatca
    14581 aaaactcgga cagattgcgg acaaatacgg caaaactatt tctcaagtca ttttacgctg
    14641 gcatatccag ctgggcgcca tccctattcc aaaatcagca tcacccgaac gccagcttga
    14701 aaacatctcc gtttttgatt tctcccttga tgaaaacgac atgaagatca tcgattcgct
    14761 tacccgcccg gacggacgca taaaaggcca agacccggcg gagtatgagg aattttaaga
    14821 agatgaataa agaaaagctg acgaaatcca ttcgtcagct tttttctaaa tctttatcta
    14881 gttctcagca aaaaaacata ctgtacatgg atttcaatat ggcataaagg catatcaatt
    14941 ttaacactca gtgttagagc cataaggagt acaccattca tctattatgg ctaacactga
    15001 atcctaaatg aaatatttat tttaatactc aactcagcaa tttttagatt cctttagtcc
    15061 ttattttttc tttaaaacgg ctgcaaaaaa ctctctgttg ttctcatatt cttcgccatt
    15121 gacatctgca tagacctttt caaggttaaa ccctgcttca ttcacttctt tttctaaatc
    15181 ttcaatgcta aaatgctggt tccaataatt ataatttact aatttcccgt catcaaaaac
    15241 caaaacattt ttcgccaaag taacattatc aggatattta attgcagcat ataaggtcag
    15301 atgttcctta tccgatatta gactgtcctt ttttgatagg aaccacatta aattctgttc
    15361 aaatttttca taactcttct ctgataagac atctaataga accaatcctc caggttttaa
    15421 accgcgatag atgttgttaa gtatttttct tctgttgttc ggactaaaaa caccataaat
    15481 ttgataaatg agcagagctg catcaaattc attttcgatt tcgagattcg taatatcttc
    15541 aatcttataa tcgatttgca aattcatttt atccgcttca ctaattgcat aatcgattga
    15601 ttttttatta taatctacac cagtcacgtt gtagcctttt aatgctaatt tttgagaata
    15661 gagccccggg ccacatccta agtcaataat tttattatta cattctactg gtgctatttt
    15721 tgtaataaaa tccacagtct catcaataaa agagctccct ttgctgccgc cgggtatata
    15781 ctcatcaaaa tgtgatttca aaacaagttc agctctatct ggatcaagcc atacctcttg
    15841 tgttccttct tcaaatggct cggggttttt cgccaattct aataattttt taattgttgt
    15901 caccttctat agttttctca tagtttgtta attataacaa agaactcttg ggtgctgatt
    15961 ctacgtacta agcacccaag aaatgataaa cttgagactt ctccgacagt ccaatacaat
    16021 gctcatcatt tatacttcat tatttattca atgaagcaag attgttttaa caatgattac
    16081 ttactgaaga aacaaaaccg ctagttgttg ttaccgtcca tgtcgttgta attgtcgcat
    16141 ctacagctat acctttgcca tctgtctctt tctctaactt ttgcaattcc aaaacatcat
    16201 tcacttttct cacctccttt cgagtgttaa taggcattca tttcttattt tatcggatat
    16261 aattttatta atttattgta actggaatat tttttatttt tgtttccact aaaaatttat
    16321 ctgtgttgac caatggcagc caataaagtg gattgctttt gacaattccc attaatgcta
    16381 acactacacc tgagctacct gtataaacat catcagataa tctataagaa aattgccccg
    16441 gataaacata ataatcattt ttctcaatta aaaagatatt aagcagattc attacttcca
    16501 taagaattct cttccggata cacccgttat taaccataga aggaattaaa aggaagctac
    16561 ctgcaccatc aaataaacct ccactgattg tgcagcgcat ctttgataga tttaaaatgg
    16621 ctctaaattc ttctttaaag agatcttgtc cacttacatg gtttaaaaac caaattgaca
    16681 cagcaactcc aatagaccct ccagaaagat atggcaatag tcggtttcta tcatctaaag
    16741 tttgtaacac accagttaca tcatcttttt ttgtcttttc caagtctttc tttaataata
    16801 actcagcttc ctctaaatac tttttattat tggttgctga ataaagcgct gaataaaaca
    16861 gagatacgcc agataatcca tcaattaaac ctatatctac ggccatccag tcattaactt
    16921 ttaatgactc ctctttaacc ttattaagct caattaactt ctctatctct ttcgcaaact
    16981 ccaagtattc tttactttcc gtctcaaaat ataaactgat taagaacagg cctatacctg
    17041 aaagacctga tcgtaaagaa atgttggttg tttcatttac attatttctt agaacattca
    17101 attcatttaa aacagcttct ttatgccccc tctcataaag cagagccaac attcctgttt
    17161 ttccagttaa taaaccatca tcaccaatcg ataggttatc caccaaaaaa tttcgaatcc
    17221 aattatctac atttttagat ttggagttac atctggtaag aatataggca gcgccacttc
    17281 ccccagtaag aaagttgaat tttcccccac tcatttcaaa ttgacgaatg tcaccgttta
    17341 caagcttttc atcatctgtt aagttatttt ctaaaccctt tatcaactta ttaatcatgg
    17401 aatttaagtt gaaatccctt ttcttgttac aaaggttaat ctctgcggga acatatttgt
    17461 gataactttt tattttatca tcacattttt tttgcaattc taaaatgaaa ttataaaatg
    17521 attctccata attcatcttt atccagtaca aatggttatc ttgcagatac ccatctatat
    17581 cgtctgaaga gagcactggc agtgttaaat atcttaccaa tctctttaat ccaaaccagt
    17641 ctcttgaacc acctgccttc atttcttgag aaacaaaccc gatagttgcc atactaggtt
    17701 tttcttcaga ttctacaggc attgcagtct caaaatctat tatcttaacg gttaagtctt
    17761 cagttaccat cacatttgct ggctgcaaat cacccatagc aactccgtta atatgcattt
    17821 gatctgtcag agcgaagagt tgtaacagta ttttttttat attcttagca tggttacata
    17881 tactatcgtc atcgtcatct tcatctctaa ggaatggata ctcttgtgca atccattgtc
    17941 tcaaatctct tccctcaatg aattcctcaa ctaaaaaatg atgttcccat tcttggaagt
    18001 actcaagtag attaaccacg ccatgtatgt tcttaagctt ttttaaagta tcatattcaa
    18061 ttttttgcct ttctaacgca tctctagacc ctccatctaa accagcattt ggtctggctt
    18121 ctttaataat aactttcaag ttatctttct ttcgagtcgc aagatatacc cctccagcgt
    18181 tactgtagct caatgcagta atgatatcat acttcgctaa gtggctttcc tcctgttgtt
    18241 ctgagtcttc agaaagattg atcgtattaa gataatcgtc aaagtctttg acaaagtcag
    18301 ggatctgata gaagggtgtt ctttgatcct taattaaatt accactttca tccctaatac
    18361 agtgctcacc atgttcatta aaaataagtt taaatccgcc atatctgtaa aatacattac
    18421 tatttttcca cctcttatca ctgagtatat aaggaccctt tttgaaatct ttagttattt
    18481 cagataagtc ttgcaacaat tcaacaaaga tttcttcatt agccgggtat accgttataa
    18541 acttgccaga agaagctcgg ttagcatttt ttgaattcat gttaataaaa ctatgcctat
    18601 cctttaggtg tttaaattca attttcttat ccatacaaaa gcgggcggcc ctatccaaaa
    18661 cactttgtgc gtcctctaac aacgaagtta aatgaatttt ccacccctgc tctggtaatg
    18721 atacaccctt aacatgataa tatttccata ctgaattact atctgagata acagtatatg
    18781 tatcagggat gtcattcact tcatatgtat tcattgtcat ctcttgtttt ccaaaatact
    18841 cagaatttgc tttcagatat tgatgatata gcatgtttcc ttccataaaa gccccccatt
    18901 tttatatgct aaatattaat tctttaacag catacaatca ataaacactc tgttaaaatt
    18961 cttttttatg atatatagct gcggcaatga aaaaagaaat gatatagaat ataaagccga
    19021 taataatata tataatcggg acatataaag aaggatttat gtgtaaaaat gacagtggta
    19081 atttttctgt tacataacca acgacacttt gcaatccaaa ggtagtaaaa agccctccca
    19141 ttgcacctcc aattacaata gcatcagatt tttcagggcc aataatgtag agaagagggt
    19201 aaacgattgc accggcaaag agaacgatga aagttccgaa agagacaata ttcaatatgc
    19261 cgtcaacagg ttcaccaaaa accaggctgt atacaaagaa aataccataa gatattacag
    19321 ccccgatcac aacaactaaa agataaaaga aatagtgact ttgaacaata tttgttctgc
    19381 tgaccggtaa agtcaggaca tacttgtcat agccagactt gctctcatac tttataacct
    19441 caagtgcagg catgacgaca aacaaaataa tcagcatagc aacaaaacga tgcatggaag
    19501 catctccaaa ataaaaaatg accgccgata tcaatatggc caaccccgtg tatgcaaaga
    19561 aacttcgata aaccaagtaa tagttagtta ataacagacc tctcattttt ttcactccta
    19621 gttaaaaaga cgctgatttc ttctattgaa atggttttgg ccgttacgcc attcggcaat
    19681 ttctgttgat ccgatacaag cacactccaa taagttccat aattcctttt tactagaatt
    19741 atatcttcgt caagcttagc catttgactt tcatcaacat ctataacagt atatctttca
    19801 agaaccttat ctttctcctc atttagtaaa atttctccat ctttcataat aatgatatgg
    19861 ctggctacct tctcgacatc agacataatg tgcgatgaaa gtaaaatacc gccgttgctt
    19921 ttactcacaa agctttttaa ttcatttaac agatcatctc ttgaagaggg atcaagccct
    19981 cccgttgctt catccagaag taataatttt gcattatgcg acaaagcaac agctacggat
    20041 aacttcattg acatgccgcg cgagaattta tttacttttt tgtccatagg tagggagaaa
    20101 gagtgaacta accgataaaa atcgtcttgg tcccaagcgt cgaatagttt cttaaaaaca
    20161 ttattcaact gctttatcgt aagatgcgca ggaagattca tcgcatcaaa tacgacccca
    20221 atatcttctt tgaactttat atgtttatcc agattctcct taccaaagat tttcaccttt
    20281 cctctatctt gagagattaa tcctaatatc gttttaaatg ttgttgattt gcctgcgccg
    20341 ttatcaccga tgaaaccgac aattgaaccg gcaggcacgt tgaatgtgac attttttaaa
    20401 acagctttat gaccaaaaga tttgctgatg tttcttattt ctaaaaggtt tgacatcatc
    20461 ccactcctat cattgttgcc aggacttttt taagaattga accggattat tgtaatttct
    20521 gcaaaaatga tgttattttc atgttttatc tagtcgacta ggtattaata atagatcagg
    20581 aagctacaaa acaaaaggga ttttaaagtc ttttttaatc atagtttgga tgtgtaatcg
    20641 attgattagg atcatataat gggatattca tgatgaaaac tgcaagaggt gacttacttg
    20701 ccggaaaaga aaatgtgtaa tttataatat atatgtattc tcatgaggta acagatttat
    20761 acatgactgt ctaattgagg agcctgttca agaatgtaat atgccctata aaggattcat
    20821 acacggaata aaacaccaaa acaaatactt attcaaaaac ctttatttga acgctaccat
    20881 tctttactaa tggttacatt tatggattct aattggaata tatttatatt ataaccatag
    20941 gtgttacttc ttttcaatat atatactgaa atttctttat aaatataaag atcttcagtt
    21001 aatcaaaaag acgtgaactt ctaattttca tactaaaaac ccctctggtt ttaaaccaga
    21061 ggggtcaaac tttccgacta tattttacat tttaagttta ctgtaaatta tttatcccta
    21121 ctccacagta acactcttcg caaggttgcg cggtttatca acgtcacagc ctcggtgcag
    21181 cgcggcgtag taagcgatca gctgcaatgg cacaacagat accagcggag caagcgcagg
    21241 gttgacttcc ggcaggatga atctgtcgtc tgcgtcttct aagcctttca gcgagatgat
    21301 gcaagtgttg gcgccgcggg ctgcgacttc cttcacgttt ccgcggatgc tcaggttgac
    21361 gtgttcttgt gtcgccagcg caaagaccgg tgttccttct tcgatcaggg cgattgttcc
    21421 gtgcttcagc tcgccgccgg cgaaaccttc cgcctggatg taagaaatct ctttcagctt
    21481 cagggcgcct tcgacacata cgaagtagtc aaggccgcgg ccgatgaaga aagcgtttct
    21541 tgaaacagtc agatattcac gcgcgatcat ttccatttcg tccttctggt cgcagagggc
    21601 ttccatggcg tttgccgcga tacccaattc tttgactaaa tcaaagccga tatccacgcc
    21661 attgcgttct gctgcaacgg acgcaaggat cgcaagtacg gcaatctgag ccgtatacgc
    21721 ttttgttgat gcaacggcga tctcagggcc tgcgtgcaga agcaatgtgt aatccgcttc
    21781 acgggacagc gtggatcccg gaacgtttgt aattgtcagc gctttgtgac ccagcgcttt
    21841 gacttgaaca agcacggcgc ggctgtccgc tgtttctccg ctttgagaaa ggaagataaa
    21901 gagcggcttc ttagacagaa gcggcatgtt gtaagagaat tcactcgcta catgcacttc
    21961 aaccgggacg tttgcccaca tttcaatata ttgtttcccg acaagaccgg catggtagct
    22021 cgttccgcaa gccacgatat aaatgcggtc cgcttccgcc acggcgtcag cgacatcgcc
    22081 ggccacagcc agtctgccgt tttcgtcctg atacgtttgg atgattttgc gcataacaag
    22141 cggctgctca tccgtttctt ttaacatgta gtgagggtat gtgccttttt cgatatcact
    22201 ggcgtcaagc tcagcgatat aagacgcacg tgtcatgact tcaccgtcaa ggtttttaat
    22261 cacggcttcg tcttttgtca cgatcaccat ttctttgtcc aaaagctcaa cgtattcatt
    22321 cgttacttga agcatagcca tcgcgtcaga tgccacgacg ttaaaagtat ctccaaggcc
    22381 gattaacaga gggcttttgt tttttgcaac gtagatggtg tctgtgtttt cgccgtcaaa
    22441 taatgcaatt gcgtaagagc cttttaacag agtcagtgtt ttgcggaacg cttcttctgt
    22501 actgagtcct cccgccacaa attgctcaat catttgaacg actacttcag tgtccgtgtc
    22561 gcttttcagt tcaacgtttt caaggtattc acgcttcagc tgaacatagt tctcgatcac
    22621 accgttatga acaagtgtaa accggccgag tgcgctttga tgcgggtgag cgttcaggaa
    22681 gcttggttcg ccgtgagtcg cccagcgtgt atggccgatt cccgcttgag attcaaccgt
    22741 ttgatccacc acttcacgaa ggtcggcgat gcggcctttt tctttgtaca catgcacgcc
    22801 ctgctcattc gccacagcga taccggcaga gtcataaccg cggtactcaa gcttctctaa
    22861 tccttttaac aaaatctctt tcgcatcaag atgaccgata taacctacaa ttccacacat
    22921 tttttcttcc tcctaaaggt gtaaaaggag acgaagaaag tcagattaca aggggacttt
    22981 caatcgtccc ctcccacatg tttttttgga agatcatgtg atttcccttt gttcggagag
    23041 tcgcccctcc ggtttgaaga aatccttacg gctgtgatct aaatgaatca gccgggaggc
    23101 atccgccgaa aattcgataa cctccatcct cgtcaactaa gccgtttttc gggcgcttag
    23161 ttcgggcgct ataattatga aagatgcaaa caatgccgcc tttcctataa atgaaaaaca
    23221 aaggctgaac aagcttgatt ttacaacatg tgccaaggac ggtcaattat ttttttgccg
    23281 ccccggcatc atgttactat cattttatgc tgatcgcact tgtcttgttc gctctctgtt
    23341 tataaacttc gctattccgc tcccatttct gtccgcacga catccacgat ttttgtgaca
    23401 tattcgtcac aaagctcttt tgttctcgct tccgccatta cgcggacgag cggctcggtg
    23461 cctgacgggc gcactaaaat ccggccgtct ccgttcattt ctttttccac ttcagaaatg
    23521 acagccttca ccttagcgtt ttcttccacc ttatatttat ccgtcacttt cacgttcact
    23581 aaaagctgcg ggaatttttt catttcacca gcaagctctg aaagggtttt ccccgatgcc
    23641 ttcagcgtat tcacaagcat gatcgccgac aagagcccgt caccggtagt gttgtaatca
    23701 aggaaaataa ggtgccctga ctgctcgccg ccgacattat agccgtcttt tttcatcgct
    23761 tctacgacat agcggtcgcc gactgccgtt tggatgcttt tgatttcttc tttttcaagc
    23821 gctttgtaga aaccgaggtt gctcatcacg gttgatacga ctgtatcatc cttcagacgg
    23881 ccttctgatt tcaaatactt cgcgcatatg tacatgatct gatcgccgtc cacgatgttt
    23941 cctttttcat caacggcaat aaggcggtcg ccgtctccgt caaacgcaag gccgatatcg
    24001 gcgttttttt ctttgacgaa agcactcagc gcttccgggt gtgtagaacc gacgccgtca
    24061 ttaatattta agccgttcgg agacgttccc attgtagaca catcagcatc aagatcggca
    24121 aaaaggtgtg tcgcaatgga agatgtcgca ccatgggcgc agtcaagcgc tacatgaatg
    24181 cccgtgaaat cctcatccgc cgtctgcttt aaaaattgca gatacttttg aacgccttca
    24241 aaataatcgt tcacaagccc gaggtccgcg cctgtcggtc tcggcagttt atcctccggt
    24301 tcatccatga gacgttcaat ctcggcctcc tgctcgtcag aaagcttaaa gccgtctcct
    24361 ccgaaaaatt taatgccgtt atcctgtacg ggattgtgag aagcggaaat catgacgccc
    24421 gcctcagcat ccatcgcttt tgttaaatag gatacccccg gcgtagaaat aacgccgagg
    24481 cgcatcactt cagctccgat cgataaaagt ccggcgacaa gggctccctc cagcatatgt
    24541 ccggagatac gtgtatcgcg gccgatcagc actttcgggc gctgtttatc tttggtcagg
    24601 acataaccgc caaaacgccc cactttaaag gccagctctg gcgtaagctc gctgttggca
    24661 acacctctta caccatctgt tccaaaatac ttgcccattt tgtatcgctc ctttttcatt
    24721 ctgttgaaga tgaatcagca cttgatccgt cttcatcctg gtcttgattt tgatcctggt
    24781 tttgactttt attctgatcg ctgtcagtgt cttcctggtt cttgttcttg tctttgtctg
    24841 cgtctccgct tgtgccgtct ttattgccgg aatcagcgga gccgccgtca tttttatttg
    24901 aacttgtgtt tttcttagaa gtcagcctga tcttaaccgt gtcttttgac aaggaccatg
    24961 tgacattttg cggcccgttt acttcaagct ttacagaatg ctctccgtca tctaagcccg
    25021 agacattggc atacagctca atgtccgact ttttcagcgc cttaatgttg gccggagagc
    25081 ctttggccgt aatatcgatc gcccgcgatt cagggtcgag aaactcaatc cgctgcgagc
    25141 ctcccagtcc gaccgtcttg attgggacat tgctaaaatc ctttttgtct tcactgtcca
    25201 ccttaacatg aagggtaatt ttccccggtg acacctttgt gacaccctta ggaagcggga
    25261 tgtcggcatc gacatccgta tctttatcaa ttttgtctaa atcaagagat acaccgtcga
    25321 taaattcaag tgaatccagc acatcctgcg ggccgtaaac cgtcacctca ctcggattcg
    25381 agtcaatgct cgcaacgctc accccatcag gaagacttcc cttcctttca attttgaaag
    25441 ggagcttttt gctcggactg gccacgggaa ccgtcacttt aatgactgac ggttcaacat
    25501 caacaggaag tgcgttgccg tctttgtcat agacggtcac cttcacttcc ttatcaatgg
    25561 tctcatttgc attttcaagg ttcacggatg ctttgacaag cgaaatgttg tcaatcacgt
    25621 ttttcgaacc cgtaatctgt acgtttttcg ggctgataat cggctgctgg ggcgtatacc
    25681 cctttttcat tttgctttta ttgtagtatt caacttcaac gggaaaactt tcagccgttt
    25741 tttcctgaat cgtaaccgtc gtgactgacg ggttaatgga tatcgtcagt ccgtccgata
    25801 catttttcgc cttcaattcg accttatggg tcccggtctt cagcttattc atatcagcgt
    25861 atatctcaaa attcttcgtc tgtctcgcct ttttcaccgc gcttgtcgag cctttaatcg
    25921 tgacatttac ggtctggggc acgccggtga ctacgtaatt cgcttcatca tagtatgctt
    25981 ttacaggaat atcagtaagc gtagcctcgt cagtcgttga tgtcggaaaa aaggattccc
    26041 ccggcttttt cggagtcggc gcctggttgt tgttaaccgc aacataaagc aggagcgcaa
    26101 agagcaatgc aatgatcttt acagcccagc ggttgtttaa gaatttatcc atttttcttg
    26161 cccctccagt accagcggtt agaagaagta tctctggcgt ttttcttaaa ctcggcttca
    26221 agcatttctt tcagtgcttc ttccgtcaat tctctgtgaa ggtctccgtt tttggccaca
    26281 ctgatggcgc ccgtctcttc ggatacgata atggttaagc tgtccgtcac ttcactgatg
    26341 ccgacagccg ctctgtgccg cgtccccagc tcctttgaaa taaacggact ttcagaaagc
    26401 ggcagataac aggcagccgc cgcaatctcg ttatttttca ttatgaccgc tccatcgtgc
    26461 agcggcgtat tcggaatgaa gatattaatc aaaagctccg agctgacctg cgcattaagc
    26521 gggatgcccg tctcaatata atcgcccatt cccgtgtcgc gctcaatggc gatgagagcg
    26581 ccgattcggc gtttcgccat gtagctgatc gattttgtaa tcgcttcaat tgtcttatgc
    26641 tgcgcttcct ccacgggggt gccgctcctt gaaaagaacc ggccccgtcc gagctgttca
    26701 agcgcccgcc tcagctcagg ctggaatata atgataatcg ctaaaaatcc ccatgttatc
    26761 gcttggtcca tcagccattg aagcgtgctg agtcccaaat atgaactggc catccggacc
    26821 aatacgatga cgacgattcc ttttaaaagc tgaaccgcct tcgttccgcg tatgaccatg
    26881 attaatttat atatcacata ccaaacaagg agaatatcaa cggcattgcc gaggtattgc
    26941 aaaaatggga tgtcctcaaa agccatttcc tcgtcctcca ggaattcagt catttcgttt
    27001 tttcgttatg aattgtgctg catgagcaat atgtacatca tatagcgtgc tcattatacc
    27061 acattttgat ttctcaagtg aaatgagcca gcgcggcaat ccataaaaaa agagtaaagc
    27121 gattatacgc tttactcatc ttcattcggg tccaaagcgc tcacaacgcc ctgccccgcc
    27181 gatttcagtt cgtaccagac ccagtcaaac aattggttaa tttcttcaat ctgcccggtg
    27241 acttgtccgg ctgaggccat gtatttttct ccgttgacga cggtcacatt gccgtcgacc
    27301 ttacctttaa tgaccagctt gccgtttttt actgtaacat cgccctttac ggtctcgcct
    27361 tcaggaacgg tgaccgtgtg attctgcacg acaaggttcg gctgtttgga cacactgaaa
    27421 ttgtggtcgt tatgccagct gttgaaaaaa ccgccgccca ttaaaatcac aaaaaccgct
    27481 gcggctgcaa tgatcggatg agttttgatc catcgtttaa cagaagcgcg ttttttctct
    27541 tttggaagat tcgccataac tttggcagta aaatcagcag gggctgtgac atgcgatgtg
    27601 cttcggacga gcgctacaga tttctccatt tcatgaaaat gccgtttgca atcctcgcat
    27661 gaccgcaaat gttgttttaa tacgttttca tcttcaggaa ggatatctcc atcaagatgc
    27721 ttatgcataa gctgaacgat ctgttcagga cagctcattt catcacccca cttaaagatc
    27781 cctcaattgt tttctaagag cctctctgcc tctgtgaatc cttgtcttga cggtgccgac
    27841 agggatattc agaatctccc cgatttcaat taaagagagt tcatcaatat actttaatac
    27901 aataaccgtt ctgtacttat caggcagctt taaaatcttt ttctgaattg tgtccgacag
    27961 ctccaacgac aatacggcgt cttcagggag aaccccgtcc gcggcgatct gcgaatacat
    28021 cgtcagccct tctgctcccg ccacttctgc gtccagatag taatcaggct ttttcttgcg
    28081 gatgcggtca atggtcaggt tggtcgcaat tctgtaaagc cacgttgaaa actttctatt
    28141 gatatcgaaa ctgtcgatat tgacatacgc tctgataaaa gcctcctgcg caatatcttc
    28201 cgcttcgtgg tcattgccga gcatgcggta gcaaagctgg taaatcttat ctttataaag
    28261 gtcaacgatt tctgcaaacg cattttgatc gccttttttg acttgcttaa ttcttttttt
    28321 aatcaggttt tccatgtttt atcttacctc tgcccttcac cggtctgtat ctatacgttg
    28381 attgttttaa aaggtttcat ttttttatta catttatttt accaaatttc aggcagggtg
    28441 tagatggaaa atacagaata tactgcctta acagcagctt aaaaatagta tatctaatga
    28501 acaatcagaa accgaactga aatgccgata aaaaaagaca ccttatgcaa aaggtgtctg
    28561 agactgggct agctggattc gaaccaacgc atgacggagt caaagtccgt tgccttaccg
    28621 cttggctata gcccaaaaat ggtggagggg gacggattcg aaccgccgaa ccctgaggga
    28681 gcggatttac agtccgccgc gtttagccac ttcgctaccc ctccgtattt ttcagaaaaa
    28741 cagtgccggc cagaggactt gaacccccaa cctactgatt acaagtcagt tgctctacca
    28801 attgagctag gccggcaaat atggtggagg atgacgggct cgaaccgccg accctctgct
    28861 tgtaaggcag atgctctccc agctga
//
