LOCUS       gnlProkkaLGKBGJBC_1    15504 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LGKBGJBC_1.
ACCESSION   gnlProkkaLGKBGJBC_1
VERSION     gnlProkkaLGKBGJBC_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 06:48:09
            Original ID  :: gnl|Prokka|LGKBGJBC_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 724802
            Orig. end    :: 740306
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15504
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:10504]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..10504
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..15504
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15504
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(1147..1962)
                     /locus_tag="ctg1_751"
                     /transl_table=11
                     /translation="MHCMFTAGVIDTLMKAGIDFDGAIGVSAGATFGCNYKSEQIGRVL
                     RYNVKYASDSRLSSLQSWLKTGDLYGADFCYHDLPVKLDIFDTVAFQKNPMDFWCVATD
                     INNGEAVYHKLISGKEADLQWIRASSSIPVFARPVEIGSRKYWDGGISDSIPIKFFEKI
                     GYDKNVVILTQSLSYRKEASKLYPALELILHKYPAVLKKLKVRAKDYNDVLNYIRKKEV
                     QGKMLVIRPPYPLEIGTMEKDPQELRHVYQIGVKEAKKNLQAIKTYLSE"
     CDS             complement(2056..2796)
                     /locus_tag="ctg1_752"
                     /transl_table=11
                     /translation="MILTDDNFASIVVAIKEGRGVYSNIRKLLIYILNSNMPEAVPSVL
                     FLLSCGAIPLALTVMEILFIDLGTDMIPALGLGREDPEKGIMDRPPRSPKDHLINKDVL
                     AKAFLWYGLIASIIATAAFFIANFYRGHIFPNLPANGWDYRQATTVTLAAIIFCQIAAV
                     LNIWYARQSMFNKYFFKNSMIFSGIIMEIVLLLCISYVPVFQPFFGTEPLIAHDWMMLV
                     CIPLPLILIDELRKWILRKESKNK"
     CDS             complement(2793..3491)
                     /locus_tag="ctg1_753"
                     /transl_table=11
                     /translation="MMTVIQSSDDTHRFNTYTKGAPNCLVDKCNSYLCDGKIQPITQQK
                     IKDKIMRANDGYAKDGLRVLGVAGRNLDQKVMDNLDLATIDTVERDLTFLGLTVMMDLP
                     RAEVYKAARECRKAGIKVTMVTGDYGLTANSIAREIGLTDPDKPLTVITEDALKTMPDE
                     ELRHYLEGEVVFARMAPEQKYRVVSMYEKMGKIVAATGDGVNEAPALKKANIGIAMGGT
                     GTDVQKKQPI"
     CDS             complement(3570..3998)
                     /locus_tag="ctg1_754"
                     /transl_table=11
                     /translation="MTVIKQKAANYDEGQIVTKHGQKWVAHIDQDDAVNLMPMIAAKKQ
                     VKIITYVPSNKVSTIKKGQKINFSVPTGDGLTSRLIGKVREIGVYPVNINKQSGYEIIS
                     TAKINDENVKYGMQGNATIVTGSSTYFEYFLDKILNKK"
     CDS             complement(3995..4162)
                     /locus_tag="ctg1_755"
                     /transl_table=11
                     /translation="MDAKDYESTEFYSYKFKNFSTMIIVPAALLVFLVFIGSFFQLDRV
                     QFLQSELLSQ"
     CDS             complement(4173..4940)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 185.8; E-value:
                     1.7e-56)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_756"
                     /transl_table=11
                     /translation="MQSEFNADTSIQNSAALEGMIEYKHVDYRYGYGTDVLKDINLKIK
                     PDEKLAIVSMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSYVNYVPQTP
                     YIFSGTVKDNLLLGCRPDISEEDVIKACQIAGIDQEIANLSLQFETKLDENTKILFGGQ
                     KQRLTIARALLSPAKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLALAERA
                     DKAVIIDQGQIVEEGSHEELMEQHGFYYDLVKV"
     CDS             complement(5001..6332)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 112.3; E-value:
                     4.3e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_757"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.4e-44, bitscore:
                     146.7, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 1.2e-191, bitscore:
                     635.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEART
                     NFEGTTALGLVKTAQKFNFKTEVVKADMSLFNEDSIQYPFIVHVLKQGELLHYYVVLKN
                     TKNYLVIADPDPSVGVIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNVWSLFPYMF
                     KQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSI
                     FSYGQNFLLNVLGQRLSIDLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALA
                     STGISLFLDLAIVIVMGLVLAAQNITLFGITLLALPVYAIVILGFTKKFKKLNDEQMES
                     NAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKAFKYSKTESLQTALKTFI
                     QLSLNVIILWVGARVVIQGQMSIGQLKTFNALLSYFIDPLQNIY"
     CDS             complement(6345..6752)
                     /locus_tag="ctg1_758"
                     /transl_table=11
                     /translation="MMERLEETITGAIQSINNLTKSGRKELVYKVGRRINKVEDTNIYY
                     LENSPTQHKVTLITETGSAEFRSNISKISDENDFLVKVSQSCVVNPNNIDSIDFSKKTI
                     TFPNCDEVIFARSFKKHVKNLLSKYPEINVK"
     CDS             complement(6829..7143)
                     /locus_tag="ctg1_759"
                     /transl_table=11
                     /translation="MKYPVIICDDDKTLANNLANNVKYAAENLVEDNTAYENVEISVEQ
                     VATTFEQVVSYVVAKDIQNAIYFLDIELSQNSEVKNGVDLAEFIKKTRSECSDYFCYCL
                     "
     CDS             complement(7289..7558)
                     /locus_tag="ctg1_760"
                     /transl_table=11
                     /translation="MYGSDILYNFECRDDITKIPNNINELDLVRIIGISCDNAIEESKA
                     LLKQKKKAHIEIMINSNENGEFEYEIQNKRRDSEISLKQIQQRG"
     CDS             complement(7628..7873)
                     /locus_tag="ctg1_761"
                     /transl_table=11
                     /translation="MVKNQKVLLKKSQQDKLIKEQKQLQDYAEYLEKSEDELRAFRHDY
                     RNMFNSLKISAQEGDTKELIQKLDEYTKTNLNAKVF"
     CDS             complement(8012..8458)
                     /locus_tag="ctg1_762"
                     /transl_table=11
                     /translation="MTWLYLLAILLSILLFYRLTHFKIIKNKFWVYLCILVVGTVCTFY
                     SYKAILIYNLITIIILNIIHRKNNNFTLITGVLIFIFSDDLIIEFFRGILLDIIGNFSV
                     SKDIVERVNLICLFCFFIATYLIGIYVGKFVIKKLIGKNFRIFF"
     CDS             complement(8464..8613)
                     /locus_tag="ctg1_763"
                     /transl_table=11
                     /translation="MKEIKKEILVKKVILTEEEMSEVVGGARVNGFIISSNFYKAFKLE
                     KFGR"
     CDS             8942..9577
                     /locus_tag="ctg1_764"
                     /transl_table=11
                     /translation="MQSKRPIIIGIAGGSGSGKTTIAHEIYDQLQQDDHILIMTQDSYY
                     KNNDNLSMADRKKINYDHPDAFDMPLLVEQLRQLMDYKAVEMPVYDFTAHTRSEKTIHT
                     EPADIIILEGILVLGEENLRDLMSIKVFVDTDDDIRFIRRLERDTQERGRSVESVINQY
                     LATVKPMYNQFIEPTKRYADIIVPEGGENDVAIDMLTTKIRSVLSTVK"
     CDS             complement(10155..10298)
                     /locus_tag="ctg1_765"
                     /transl_table=11
                     /translation="MNDKLKDILLNSLSFFLFQVVVLLAFKWNNKQNVNIDYSTLATLA
                     IR"
     CDS             complement(10295..10504)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_766"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.2e-08,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLNMNELKNVKGGTNWGQIGGACAGGAIWGLYFGNPLLGCANG
                     VAGSLITQNLKSLKFPPKKVTMNK"
     CDS             complement(10511..10678)
                     /locus_tag="ctg1_767"
                     /transl_table=11
                     /translation="MGTCARLIGGGAAWGAVKGAGKGVPIGAVGGAVLGANTGAINGAF
                     ACAGMVIGKR"
     CDS             complement(10864..11658)
                     /locus_tag="ctg1_768"
                     /transl_table=11
                     /translation="MIFEKLFSKENKKDEIVRVKISYEEFNELKIKLSSGDVTVEQGEH
                     FAVNFIGKRHYLPIVQLENGKLQLKQRINLIDNGEAHLKVLVPADVTLDRLDVQTNSGD
                     IEIVDTKAEKAYLKSTEGRVRVRRVAIAESLLESTDGNVTVRNSDLADGKLATYDGEIK
                     VSGSTLSQISLNVTDGDMNLTDVTIDGGSANLKAGNFTLDHAVFKSDYDINNIEGNNTV
                     WSANLKYARVRTANGLNNISFDPQPSGVILTMTTVDGDNVVE"
     CDS             complement(11759..12292)
                     /gene_functions="regulatory (smcogs) SMCOG1278:PadR family
                     transcriptional regulator (Score: 140; E-value: 1.2e-42)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_769"
                     /transl_table=11
                     /translation="MPKKRILPYIILGILDQNPGSTGKFITNQFKNEIGEFWKASHSQI
                     YPELKKMVENDWIKQTSDSNNEKEKYYHLTNLGKEKLNSWIDIPINALPVVEDLFSLKL
                     FFIQDPNDPRISTLVNKQLDLLEKQLDHLNDREKILFDTQEKRNKNYGHYLILERAISR
                     LDNQIKWLKTIKQR"
     CDS             complement(12357..12572)
                     /locus_tag="ctg1_770"
                     /transl_table=11
                     /translation="MHESREKYETYPKLVVPEFAKITYIGEAGVNNDEVIAEAPYEGMT
                     DDIRNGNYYDEHYQIIQKEGHNYLEK"
     CDS             complement(13050..14975)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145:Glucose-specific phosphotransferase enzyme IIA
                     (Score: 42.5; E-value: 4.7e-13)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_771"
                     /transl_table=11
                     /translation="MVQDTTNLLAPATGAVIALAKTSDPVFSQGTMGDGFGLTPTIGKV
                     GAPVSGKISMVADTKHAVGIVTEEGLEVLVHMGVDTVGLKGAPFTIKIKNGQEVKAGQE
                     IAEMNLEEIKAKGLDTTIMVLITNSADKLSGLDVTEGEAKAGEVVATAYLKAAKTEDIS
                     SKKLSYPELATFIIKNVGGKDNVNNVIHCITRLRFYLKDESKANDEALKNQRGILDVMH
                     ASGQYQVVIGNEVTNVFDEVVKQLGPLDSETAPAPEDDGKNPVSRAFGNLIGFITGSMS
                     PIIGVIAAAGIIKGILALLTLPQLGSLLSVKSTAYITTSAIADSAFFFLPILVGYCAAK
                     RLNSDSIIAAVIGGVLVYPQLVDWGKAFKTMFEVGGIKFEFLNYTYSIFPMILAAWLAK
                     KCEDWLKKWLPSYLQMIFFPLITVLVVSALTLMVTGPIIQGVANGIAVFINWLVHASGW
                     VGGFIIGGFYQVLVIFGLHWGVVPLVAQQIAGTGESALNAIICSSMIAQGAAVLAVAIK
                     SKKEDLKELGFASTISAMCGVTEPAVYGISLRYKKVFISGCIGSAFGGLVTGLMHGTMY
                     GFTGGLIGFSSFFNPKHPTDLSSFYTFLIASTVTIVVSFIVTWVWGYNDKMVQGAKVAK
                     KRPGSK"
ORIGIN
        1 aaaatttgta ccatttgcgg cgtaccacgg ataaattcaa tgtagcaaac agcaagccag
       61 tgtaaaattg gattctttga taaacgcatc aaagctaaaa tgatacctaa aacaatacca
      121 ataattactg aaaaaatagt aattacgatt gtataccaaa tacccttaaa gaaatatgga
      181 atgtacttgg caaaagtatt acttttcttt tctgttttca tatatttagc agctgctggt
      241 aaatattctt tactaatcaa gtcttttttc tgaacttggt caattgtttt gtttacttga
      301 gctactaaat catcttgtcc tttagcaatt gcaactgcat ttcccgcttg agtttctttt
      361 aagtttgaac gaactgcagc caagccacta ttattttcgg catatgcttt agcaattaat
      421 tcttctacta ctactgcaga aaccttgcct gattgcaagg ctaaaacaag attgttaatt
      481 ttcccaagac cctttaattt agaatctttc atttgagatt taactaaatt atattggtta
      541 ctccccgttt gtgctccaac cgtttgacct ttaagacttt ggatacttgt gtatttgtct
      601 ttatcctttt tatttactaa gaaatattca ccacttggct tatagtaaat ttttgaaaat
      661 gctacacttt gctttctttc aggagtgggc gtcatggcag aaataaccat atctaccttt
      721 cctgtttcga gtgcaactaa caaggagtca aaagacatat tcttaataac taacttcaca
      781 cctaagtctt tagcgatgtc tttggctagt tcaatatcta ctccaacata tttagtctta
      841 ccattttcac ttgcggtaaa ttctagtggc ggataatcag cagatgtgcc gactactaat
      901 tctccactct ttttaatctt cttcaagaca ctaccttctg ctacttgctt ttggctagtc
      961 gcttgagctg gcttgataaa agtagcaccg agtgagaaaa acatcaaaag tgcaaagaaa
     1021 aagctaaaaa gctttgtttt tttcattacg ctcattccct ctataattac tattaaaaaa
     1081 ctgaaaattt aagcttttgt taattatagc gaataaaatg taatctggac aagtcattca
     1141 agaagattat tcactcaaat aagtttttat tgcttgtaaa tttttcttag cttcttttac
     1201 accgatttgg tatacgtgcc tcaattcttg gggatctttc tccattgtgc caatttccaa
     1261 aggataaggt ggtctgataa ccaacatttt gccttgtact tctttttttc taatgtaatt
     1321 aagcacatca ttataatctt ttgctcttac ctttaatttt ttcaagacag cgggatattt
     1381 atgtaagatc aattctaaag ctggatatag tttacttgct tcttttcgat aagagaggga
     1441 ctgcgttaaa atgacaacgt tcttgtcgta gccaattttt tcaaaaaatt taatgggaat
     1501 tgaatcacta attccaccat cccaatactt acgactccca atttcaactg gccgagcaaa
     1561 aactggaatt gaagaagaag cccggatcca ctgcaaatct gcttctttac ctgaaatcaa
     1621 tttatgatat actgcttcac cattattaat gtcagttgcc acacaccaaa aatccattgg
     1681 atttttttga aaagcgactg tatcaaaaat atcaagttta actggtaagt catgataaca
     1741 aaagtcagcg ccatataaat caccggtctt tagccacgat tgcaaactag ataaacgtga
     1801 atcactagca tattttacat tatagcgcag aactcttcct atttgttcag atttataatt
     1861 acaaccaaat gtagctcctg ctgacacacc tattgcacca tcaaaatcaa tgccggcttt
     1921 catcagagta tcgattactc cagcagtaaa catgcagtgc atccataact aatccttttt
     1981 tcatcctttc gccaccttcc gtatttttac tattttagca agaaaaaact gctagttaaa
     2041 actagcagtt aaagtttatt tattttttga ctcttttctt aaaatccatt ttcttaactc
     2101 gtcgattaga attaatggta atgggataca tactagcatc atccaatcat gtgcaataag
     2161 cggctcggta ccaaaaaatg gctgaaagac tggcacataa gaaatgcata gtagcaagac
     2221 aatttccata ataatcccac taaaaatcat cgaattttta aagaaatatt tgttaaacat
     2281 tgattgtcta gcataccaaa tatttaagac tgccgcaatc tgacaaaaaa taattgccgc
     2341 taaagttaca gtagttgctt ggcgataatc ccagccattt gctggcaaat taggaaaaat
     2401 atgaccacga taaaaattag caatgaagaa ggcagctgta gcaattatcg aagcaattaa
     2461 accataccag agaaaggctt ttgccaggac atctttatta atcaaatgat cctttggtga
     2521 tcttggagga cgatccataa ttcctttttc aggatcttct cgtcctaaac ctagagctgg
     2581 aatcatgtca gtacctaggt caataaataa aatttccatt acagtcaaag caagtggaat
     2641 tgcgccacat gaaagtaaaa acaaaacaga tggaacggct tcaggcatat ttgagttcaa
     2701 aatataaatt aataacttac gaatattgct gtatacaccg cgtccttctt taatagcaac
     2761 tacaatagaa gcaaaattat cgtcagtcaa aatcatatcg gctgcttctt ttgcacatca
     2821 gtacccgttc cacccatagc gataccgata ttcgccttct ttaaagcagg tgcttcatta
     2881 acgccatctc cagtagcagc aacgatttta cccatttttt catacattga aacaacacgg
     2941 tatttttgtt caggggccat tctagcaaaa acaacttcac cttccagata atgtcttaac
     3001 tcctcatcag gcatcgtctt taaagcatcc tcagtaatga ctgtcagtgg tttatccgga
     3061 tcagtcaagc caatttcacg agcaatacta ttagcggtca aaccatagtc accagtaacc
     3121 atcgtaactt taatcccagc cttgcggcat tcacgtgccg ccttataaac ttcagctctt
     3181 ggcagatcca tcataacggt taaccctaag aaggtgagat ctctttcaac tgtatcaatt
     3241 gttgcaagat ctaaattatc cattaccttt tgatcaagat tacggccagc aactcctaag
     3301 acacgcaagc catccttagc atagccgtca tttgctcgca taatcttatc ttttattttc
     3361 tgctgggtaa taggctgaat tttaccatca cataggtacg agttacattt atcaaccaga
     3421 caatttgggg cacccttagt ataggtattg aaacgatgtg tatcatcgga gctctgaatc
     3481 actgtcatca tttttctact tgaatcaaat ggcaactctt taacgcgtgg agtcttttct
     3541 acttctgctt taacatcatt ttatcaacct tatttcttat tcaagatctt atctaaaaag
     3601 tattcaaaat aagtgctact ccccgtgaca attgtcgcat ttccctgcat cccatactta
     3661 acattctcat cattaatttt cgcagtcgaa atgatctcat agccactctg cttatttata
     3721 tttactggat aaacgccaat ttctctcact ttaccaatta atctactggt caagccatct
     3781 cctgttggga cagaaaagtt tatcttctgt ccctttttaa tagtcgaaac cttattactt
     3841 ggtacataag tgattatctt cacctgtttc ttggctgcta tcatgggcat caaattaact
     3901 gcatcatctt gatcaatatg agctacccat ttttgcccat gttttgttac aatttgcccc
     3961 tcatcataat tagcagcttt ttgtttaatc acagtcactg gctcaataac tccgactgaa
     4021 gaaactgtac tctgtctaat tgaaaaaaag aaccaataaa tacaaggaag acaagaagag
     4081 cagctggaac aataatcatt gtcgaaaaat ttttaaattt ataggaatag aattctgtac
     4141 tttcatagtc ttttgcgtcc atttatcctc acctatacct ttactaagtc ataataaaaa
     4201 ccatgttgct ccataagctc ttcatgactt ccttcttcaa caatctgtcc ctggtcaatt
     4261 ataaccgcct tatctgcacg ttccgcaagg gctagacggt gtgcaataaa aatgattgtc
     4321 ttgtctttta gtttcataag attgtcaact actctttttt ctgtaattgt atctaaacca
     4381 cttgttactt catcaaatat aaaaactttt gctggcgaga gtaatgctct agcaatagtt
     4441 aatctctgct tttgtccacc gaataaaatc ttggtattct catctaactt tgtctcaaat
     4501 tgtagggaca aattagctat ctcctgatca atgccagcaa tctgacaggc tttaattaca
     4561 tcttcttcgc taatatcggg tctacatccc agtaataaat tatccttaac tgttccagaa
     4621 aagatatatg gcgtttgagg aacatagtta acatacgaac gtaaggtatg tttattaact
     4681 tcactagttg catgaccatt taaagttact tctcccttac ttggtgaaaa gaaatcaact
     4741 agtaacttaa ccatcgtaga ttttcccgat ccactcatgc taacaattgc taatttttca
     4801 tctggcttaa tttttagatt aatatctttt aaaacatcag taccataacc atatcgataa
     4861 tcaacatgct tgtattcaat cattccttct aaagcagctg agttctggat agaagtatct
     4921 gcattaaatt cactttgcac ctgataaacc tcgttcaatc tattttgtgc aacactagct
     4981 gatgaagacg aggctgtaag ttaataaata ttttgaagtg ggtcgatgaa ataagatagt
     5041 aatgcattaa aagtctttaa ttgaccaata ctcatctgtc cttgtatcac tactcttgct
     5101 ccaacccata aaataattac attaagagat agttgaataa atgtctttaa cgccgtctgc
     5161 aaactctcag tcttactata tttaaatgcc ttctttaaat agtttacaaa ttgactatcg
     5221 attctacgat atcttgtatc ttcactattt agagctttga tagtttcaat gccttgaata
     5281 tcttctataa ctgaagaact tagcactgca ttactctcca tttgttcatc atttaatttt
     5341 ttaaatttct tagtaaatcc tagaattact atcgcataca ctggtaaagc taataatgtg
     5401 atcccaaata atgttatatt ttgagcagct aatactagtc ccatcacaat tacaattgct
     5461 aagtctaaga aaagcgaaat accagtactt gctagagcat caataattct acttgcatca
     5521 gagaagcgtg aggtaatctc accagttctt ctagttacaa agaattccat tggcaattca
     5581 aaaatatgcc ttatatattg gaggtttaaa tcaatactta atctttgacc taaaacattt
     5641 aataaaaaat tctgtccata agaaaatatt gaattaaaaa tataagcaat taataatcca
     5701 acagctaaaa ttgaaagagt ctgataagtt ccatcgggaa tataagtatc gattattcct
     5761 tgcacaaagt atgaactaca aatactaatt attgtcatta ataaagcggc taaaatgata
     5821 ttaatcatta gccgcttttg cttaaacata tatggaaaga gagaccatac gttatttttc
     5881 ttttctttaa ttggttcaaa atcttcattt ggaaccataa aaagcgcaat accagtccat
     5941 tcttgagcaa acttatcctt aggcatcttt attacgccaa ctgatggatc agggtcggca
     6001 attactaagt aattcttagt atttttaaga actacgtaat aatgaagtaa ttctccttgc
     6061 ttaagaacat gcacaataaa agggtattga atactatcct cattaaaaag agacatatca
     6121 gcttttacga cttcagtttt aaaattaaat ttctgtgcgg ttttaactag tcccagggca
     6181 gttgtacctt caaaatttgt gcgagcttcg tgacgcaaat gtgctaaaga tacacgagaa
     6241 tgatactgct ttaaaatcat tgctagacaa gcaactccgc aatccatttc atctacttga
     6301 ggtacataaa cagatttata tttaaataac ataagtctta ccttttattt aacgttaatt
     6361 tccggatatt tacttaataa attcttgaca tgttttttga agctacgagc aaatattact
     6421 tcgtcacaat tcggaaatgt tatggtcttt ttcgaaaaat caatgctatc aatattattt
     6481 ggattaacta cgcatgattg agatacttta acaagaaagt cattctcatc actaattttt
     6541 gaaatattac ttctaaattc agctgaacca gtttcagtta ttaacgtaac tttgtgttgt
     6601 gtaggactat tttcaagata atagatatta gtatcttcta ccttatttat cctgcgtccc
     6661 accttataaa caagctcttt tcttccagac tttgtaagat tgttaatact ttgaatcgcc
     6721 ccagtaattg tttcttctag acgttccatc atctcttttt ggtctagtgc tttattaata
     6781 tagtcaattg caccaattcg tcttcgataa gttaagggag cgtacttatc ataagcagta
     6841 acaaaaataa tctgagcatt cggatcttgt ttttttgatg aattctgcta aatctactcc
     6901 attcttaact tcagaatttt gacttaattc aatatctaag aagtaaattg cattctgaat
     6961 atccttagcc actacataac ttacgacttg ctcaaaggta gtggcaactt gctctacact
     7021 aatctccaca ttttcataag ctgtattgtc ttcaactaaa ttttcagctg cgtatttcac
     7081 attatttgct aaattatttg ctagtgtttt atcgtcatca caaataatta ctggatattt
     7141 caatgttttt tcactcctct ggttcaatta cgagatagaa atcaaagtat cccttcggta
     7201 tctcataaga aatcgtcata ttttcatatt tattcttaat actgttgata ttggctagac
     7261 ccatgccaga gtgacttttc ttcgttgatt aaccgcgttg ctggatttgt ttaagtgaaa
     7321 tttctgaatc tcttctttta ttctgaattt catattcaaa ttcgccattc tcatttgaat
     7381 taatcataat ttcaatatga gcttttttct tctgtttcaa taatgcttta ctttcttcaa
     7441 ttgcattatc acaactgatg ccaataattc taactaaatc caattcatta atattgttag
     7501 ggattttagt aatatcatct ctacattcaa aattatatag aatgtctgat ccatacattt
     7561 ctgttaactt agcaataata atgcttttca aagattttac tttaatgtga ttaacatctc
     7621 tatactttta aaatactttg gcatttaaat tagtcttagt atattcgtct agtttttgaa
     7681 ttagttcttt cgtatctcct tcttgtgcac tgatttttaa tgaattaaac atatttcgat
     7741 aatcatggcg aaaagcacga agttcatctt cgctcttttc aagatactcg gcatagtctt
     7801 gcaattgctt ttgttctttt attagtttgt cttgttggga cttctttaga agtacctttt
     7861 gattttttac cattaagtaa tacaaaccta tagaaaaaat aaattggatg gtcaaaaaag
     7921 atataaagaa aattgtaaca ggaggaacat ttttagtttc agcatataca atagcaataa
     7981 tcagagttac taaatataaa tatagtaata ttcaaaagaa aattctaaag tttttgccta
     8041 ttagtttttt tataacaaat tttccaacat agattcctat taaataagta gctataaaaa
     8101 aacaaaaaag acatattaaa tttacccgtt ctactatatc tttcgataca gaaaaatttc
     8161 caattatatc cagtaatatt ccccgaaaaa attctataat taagtcatca ctaaatataa
     8221 agattaatac tccggtaatt aaagtaaaat tattattttt tctgtgaata atgttcaaaa
     8281 taataatagt tataaggtta tatattaata tagccttata actataaaat gtgcacacag
     8341 ttccaacaac taaaatacat aaatataccc aaaacttatt ttttattatt ttaaaatggg
     8401 taagtctata aaataataaa atagacaaaa ggatagctaa caaatagagc caagtcattt
     8461 attttatcta ccaaattttt cgagcttaaa agctttataa aaattagatg aaataataaa
     8521 gccatttact ctagctccac caacaacttc actcatttct tcttcagtta aaataacttt
     8581 cttaacaaga atttcttttt taatttcttt cattattctt ctctccttta aagcaattaa
     8641 taacattttt acgtcttaca cattaccatt ttttattctc taaaaaatca aaaaatatca
     8701 aattggtcaa tttgattact gatttagtat tctttttcta taacgtacta ctagtaaata
     8761 tatatttttt tgaaagagaa ttaattttat aaatattagt agtgaacaag gtatttattt
     8821 ttaactagct ccaaattatc tcactataaa aaacatattt gtcaagatta ttgctcataa
     8881 agctatcata gcgcataatt ttaaggtatt attgtaatag tttaaaaaag gagattttat
     8941 tgtgcaaagt aaacgcccta ttatcattgg aattgctggt ggttctggta gtggtaaaac
     9001 aaccatcgcc catgaaattt atgaccaatt acaacaagac gaccatatct taattatgac
     9061 gcaagattct tactacaaaa acaatgacaa cttatcaatg gcagaccgta aaaaaatcaa
     9121 ctacgaccat cctgatgcct ttgatatgcc acttcttgtt gaacaattac gtcaattaat
     9181 ggactacaag gcagttgaaa tgccagttta tgactttacc gctcatacaa gaagtgaaaa
     9241 gacaattcac actgaaccgg ctgatattat tattttagaa ggtatcctag ttttaggcga
     9301 agagaattta cgtgatttaa tgagtattaa agtatttgta gatactgatg atgatattcg
     9361 ttttatcaga agattagagc gtgatacaca agaacgtgga cgttctgtag aatcagtaat
     9421 taatcaatac ttagcaacag ttaagccaat gtataatcaa ttcattgaac caactaagcg
     9481 ttatgctgat attattgttc cagaaggtgg agaaaatgat gttgctatcg atatgcttac
     9541 tacgaagatt cgttcagttt taagtacagt caaataaaaa taacctcgtg gttttccacg
     9601 gggttatttt tcaacaaaaa agaaactcat tataattcca gcaatcagac ttccacgtat
     9661 taatccaaga tattctgacg ttttcagtat taagctttga gcttcactcc aattagaaat
     9721 tcccattact atagaactta ttacaaagaa tgagactgta ttaataataa ctgctttcaa
     9781 gctactataa atttcttagg cgaaaaatat agggcctcta aattggttta attcttttat
     9841 cctacgccat aagtaatctc tttattcttc acagaattag aagagatgaa gattttttta
     9901 ctaaaaaact tgtcgataga agagatatta tatgctatcg acaagagaag ttatacagtt
     9961 ataaaatttt agagcaaaat caaagaaaca ctgctcatat caataaaata atcaaccaat
    10021 tcagtttgct agtatattgt aacttattta cttaagatgc gagagggatt tctaagtgac
    10081 acgatttgta agaactatta ttttttctag aatctctttt accaaaaaaa gattcattaa
    10141 aattccaaaa actattacct tatagcaaga gttgcaagag tagaataatc aatattaacg
    10201 ttttgcttat tattccactt aaaagcaagc aaaaccacta cttgaaaaag aaagaatgat
    10261 agactattta acagtatatc ttttagttta tcattcattt gttcatagtt acctttttgg
    10321 gagggaattt taaagatttt agattttgtg ttattaggga accggcaact ccattggcac
    10381 atcctagtaa gggatttcca aagtaaaggc cccagattgc ccctccagca cacgctccac
    10441 ctatctgacc ccaatttgtt ccacctttta cattttttag ctcattcata tttaactttt
    10501 tcattttgat tcatctcttt cctataacca tacctgcaca agcgaaagca ccattaattg
    10561 ctcccgtatt agcacctaaa acggctcctc cgacagctcc tataggaaca cccttaccgg
    10621 cacctttgac tgcaccccaa gccgcaccac ctccaattag tctagcgcac gtacccacat
    10681 tttttcggct tcctccacca cgaatttctt tcaattatat atctgtaatt cttttcatat
    10741 tttttcttct cctttatttc tttacatata ataatatccc aaatcattta tacgatttgg
    10801 gatataacga atatagctct ttttttgtat taattttgca attttgtacc aaattaatac
    10861 ttcttattcc accacattat ctccatctac tgttgtcatt gttaagatca ctccagatgg
    10921 ttgcggatca aatgaaatat tatttagtcc attagctgtt cttacacggg catactttaa
    10981 attggcactc cagacagtat tatttccttc aatattatta atatcgtaat cgctcttaaa
    11041 gacagcatga tctaaggtga aattaccagc ctttaagttt gcacttccac catcaatagt
    11101 tacgtcagtt aaattcatgt ctccatcggt aacattcaat gaaatttgag ataaggtaga
    11161 tccagatact ttaatttctc cgtcatatgt agccagcttc ccatcagcta aatcactatt
    11221 tctcacggtt acattaccat ctgttgattc aagaagagat tcagcaattg caacacgtct
    11281 tactctaact cttccctcag tcgatttaag atatgctttc tctgctttgg tatcaacgat
    11341 ttcaatatca ccactattag tttgaacatc aagccgatct aaagttacat ctgctggtac
    11401 aaggacttta agatgcgctt caccattatc aattaaatta attctctgct taagctgtaa
    11461 ctttccattt tccaattgaa caataggtaa gtagtgtcgt ttacctataa agttaactgc
    11521 aaaatgttct ccttgttcaa ctgttacatc cccgctactt agttttattt tcaattcgtt
    11581 gaattcttcg tagcttatct ttaccctaac aatctcatct tttttatttt ctttagaaaa
    11641 aagcttttca aagatcatag cctttccccc aatctacgac acaattaaat tattattaat
    11701 tatattaata cgatttaata ttttcaacta ttgaattcaa aaaaacagcg ctgaattatc
    11761 aacgctgttt tatcgttttt agccacttaa tttggttatc aagtctacta attgcacgtt
    11821 ctaagatcaa ataatggcca taatttttat ttcttttttc ttgagtatca aatagtattt
    11881 tttctctatc atttaaatga tcaagttgct tttctaatag atcaagttgc ttattaacta
    11941 aagtcgaaat tcttggatca ttcgggtcct gaataaagaa taattttaag gaaaacaagt
    12001 cttcgactac tggaagagcg ttaataggaa tatcaatcca tgaatttaat ttttcttttc
    12061 ccagattagt taaatgataa tacttttctt tttcattatt actatcacta gtttgtttaa
    12121 tccaatcatt ttcgaccatt ttctttagtt caggataaat ctgactatga gaagctttcc
    12181 aaaattcccc aatttcattt ttaaattggt tagtaataaa ttttcctgtt gaaccaggat
    12241 tctgatctaa aattcctaga ataatataag gtaaaattcg cttttttggc atctaatctt
    12301 cttttctatt ctatagctaa tagttttatt ctaacaaaaa agttattatt acctcattac
    12361 ttttcaagat agttatgacc ttctttttga ataatttggt aatgctcgtc atagtaatta
    12421 ccatttctga tatcatcagt catcccttca taaggagctt cagcaattac ttcatcatta
    12481 tttactccag cttctccaat ataagtaatc ttcgcaaatt ctgggacaac cagcttagga
    12541 taagtttcat acttttctcg agattcgtgc attaaatcga tgtggtcatt ttgatagcaa
    12601 acaataatct cgggatgatc ttgtacccac ttaggaaaga agatagttcc atttaattta
    12661 tattcattag gaacaaaatc tagggtaaca tcagtaccag ttggttcagt ctacgcaatt
    12721 ttgtaaattc catcagttaa aagattaata tgtgcttctt gatctttaac ccaacgtcct
    12781 tttaccattc caccatgaat acgataatca acagtatgat catttttgca gtaccattca
    12841 tattaccaac cattgtcata agtataaata aagtgagtgc ctacaaaatc atctaaggtc
    12901 ttaaattttt ttcattttat ttaaattagt cattttcatc atccttttat attttatgtt
    12961 tttatcgaca tatttattat atgactatat cgacaaaaaa tgcagacaaa aaaatagaga
    13021 actatttttc aataattctc tactttatgt tacttactac ctggtctctt ctttgctacc
    13081 ttagcacctt gtaccatctt gtcattgtag ccccataccc aagttacaat aaatgaaact
    13141 acaatagtta cagtactagc aattaagaag gtgtagaaac tagataaatc agttggatgt
    13201 tttggattga agaatgatga gaatccaatc aaaccaccag taaagccata cattgttccg
    13261 tgcattaagc cggtaaccaa tccaccaaag gcagaaccaa tacatccaga aataaatact
    13321 ttcttatatc ttaaactaat accataaacg gctggttctg ttacaccgca cattgcagaa
    13381 attgttgaag caaaacctaa ttcctttagg tcttctttct ttgacttaat agcaacagct
    13441 aatacagcag caccttgagc aatcattgat gaacaaataa ttgcgtttaa tgcactttca
    13501 ccagttccgg caatttgttg agcaacaagt ggcacaacac cccagtgaag gccaaagata
    13561 accaacactt ggtagaaacc accaataatg aatccaccaa cccagccaga tgcatgaact
    13621 aaccagttaa tgaagacagc aataccgtta gcaacacctt gaataattgg accagttacc
    13681 atcaaagtta aagctgatac aactaaaaca gtaattaatg gaaaaaaaat catttgtaag
    13741 tatgatggta gccacttttt aagccaatct tcacattttt tagcaagcca tgcagctaaa
    13801 atcattggga aaattgagta cgtatagttc aagaactcaa acttaattcc gccaacttca
    13861 aacatggtct tgaaagcttt accccaatca accaattgcg gataaacaag cacaccacca
    13921 ataactgcgg caatgattga atcagaattt aaccttttag ctgcacaata ccctactaaa
    13981 attggtagga agaagaatgc ggaatcagcg atcgcactag ttgtaatata agctgtactc
    14041 tttacactaa gcaaactccc taattgagga agagttagga gggctaatat ccccttaata
    14101 ataccagctg cagcaattac tccaataatt ggactcattg aaccagtaat aaagccaatt
    14161 agattaccaa aagctcttga aactggattt ttaccatcat cctctggtgc aggagctgtt
    14221 tcactatcta aaggtcctaa ttgtttaact acttcgtcaa aaacattagt aacttcatta
    14281 ccgattacca cttgatattg acccgaagca tgcattacat ccaaaattcc gcgctgattt
    14341 ttcaaagctt catcatttgc tttactttca tcctttaagt aaaaacgcaa acgtgtaata
    14401 cagtgaatca cattattaac attatcctta ccaccaacat ttttaataat aaaggtagct
    14461 aattctggat aggataactt tttgcttgaa atgtcttccg ttttagctgc ttttaaatat
    14521 gcagttgcaa ctacttcacc agcttttgct tcaccttcag ttacatctag tcctgaaagc
    14581 ttatctgctg aattagtaat taaaaccatg attgttgtat ccaatccctt agccttaatt
    14641 tcctctaagt tcatttcagc aatttcttgg ccagccttaa cttcctgacc atttttaatc
    14701 ttaatggtaa atggagctcc ctttaagcca acggtgtcca cacccatatg aactaacact
    14761 tctagtccct cttcagttac gataccaaca gcatgtttag tgtcagcaac catactgatt
    14821 ttccctgaaa caggtgctcc aacctttcca atggttggag ttaatccaaa cccatccccc
    14881 attgttccct gagaaaagac tggatcggaa gttttagcca aagcaataac cgctccagtt
    14941 gctggagcta ataaattagt agtatcttgt accataattt cattctcctc ttttaaagta
    15001 tccgctttca tttatcttga tttaaatatt atacttgtct gtacaagttg tcaatatatt
    15061 tttatgaaaa agcttacttt tctattaaat caatatttta taaataaaaa tatttttctt
    15121 tacttgtcta atcaagtgta tataattaaa gacaaaggag gattttttat ggcccaatct
    15181 aaagttggag taatcgccca agacttagtt gataaaatta aacatcaaca atatcagcct
    15241 ggcgactacc tcccaagtga acatcaatta atggatttat atagcgcttc tcgtgagaca
    15301 attcgaaaag ctcttaacag cttaactgac ctaggactaa tccaaaaaat tagaggaaaa
    15361 ggttcaattg tattgaattt agatcgttat acttttccaa tttccggaat tactagtttt
    15421 gcggaattga ataaccaatt aggattaaaa gctgagacaa aagtattact tctacaaaaa
    15481 gaagataaat taccagcgca attt
//
