LOCUS       gnlProkkaFMNCCNKH_13   13188 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FMNCCNKH_13.
ACCESSION   gnlProkkaFMNCCNKH_13
VERSION     gnlProkkaFMNCCNKH_13
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 20:54:33
            Original ID  :: gnl|Prokka|FMNCCNKH_13
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13188
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13188
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1522:3188]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1523..3188
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..13188
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13188
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(108..1526)
                     /locus_tag="ctg13_1"
                     /transl_table=11
                     /translation="MSMTTPIVDFVRSYAQSGTARLHMPGHKGQSLLGFEPLDITEICG
                     ADELYAPEGIIAESEANATRLFGTAHSYYSTEGSSQCIRAMLFLALQGAPQSGKRPVLL
                     AARNAHKALLYAAALLDFDIRWLWPSAQAEGALCSCPVTAEALTGALHAMAQQGNTPFG
                     VYVTSPDYLGGVQELPALAAVCRAQGVPLLVDNAHGAYLRFLPQNCHPIAQGAAMCCDS
                     AHKTLPVVTGGAYLHLAHDAPVQDEAAVRGALALFGSTSPSYLILQSLDACNAVLAGDY
                     PRRLVQCCAALEGLRRSLNKTAAARQCPVPLAVAGAQQEPMKLTLDAAALGCTGTALAD
                     ALRRAQLECEYADPRYVVLMFTPENPPQDYTRLQTVLEQLLAAVPAGLLRPENRAGEFA
                     ALQQQAAQRCTIRQAVLGAQVRVPVHKALGRVCAMPTVSCPPAIPVAVSGEEITPAAIV
                     LMQRYGIEELSVLR"
     CDS             complement(1523..2974)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_2"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.6e-30,
                     bitscore: 97.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.3e-15, bitscore: 49.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4e-16, bitscore: 51.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.3e-20, bitscore:
                     63.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYQLNGYNIVLDTCSGSVHVVDEVAYDVIAMYPEHTADEIVA
                     AMLAKYGSRPDVTEEDLRQCIDDVTSLKENGKLWSPDVYKDMAFDFKNRNTVVKALCLH
                     VAHSCNLSCSYCFASQGRYHGDRALMSFEVGKRAMDFLIENSGTRRNLEVDFFGGEPLM
                     NFEMVKKLVAYCREQEKIHNKNFRFTMTTNGVLIDDDVIDFCNKECHNVVLSLDGRKEV
                     NDRFRVDCAGNGSYDRIVPKFQEFVKKRGDKNYYMRGTYTHFNTDFTNDIFHMADLGFT
                     ELSMEPVVCDPSDPSALTEADLPILKEQYEILAKEMIKRDREGRGFTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDPKYLLGDIWKGVTNTAVRDEFKHCNA
                     YARKECQDCWAKLYCSGGCAANSYHATGSITGVYEYGCELFKKRMECAIMIKVAENQEL
                     AAKGIEVPIELGSTCNACADGEACE"
     CDS             complement(3042..3188)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_3"
                     /sec_met_domain="TIGR03973 (E-value: 5e-26, bitscore: 82.1,
                     seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.8e-25, bitscore: 79.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIKTIATRDLTKSVKTGGCGECQTSCQSACKTSCGVANQQCEN
                     SNK"
     CDS             complement(3485..3772)
                     /locus_tag="ctg13_4"
                     /transl_table=11
                     /translation="MPERTTQNAQTLLSPRVPRDTEHERYHPELEEELKECLFCLKRNE
                     MMFDMEVDTDLIEQRIYERQALLCRYRYLLARARELGLHTVLTRYQPMGG"
     CDS             complement(4209..5969)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283:2`,3`-cyclic-nucleotide 2`-phosphodiesterase
                     (Score: 253.4; E-value: 8.2e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg13_5"
                     /transl_table=11
                     /translation="MKQLISRRCFLKAAGVTAAAASMAIGAPAASACWYGDKSDVTILY
                     TNDVHTYIDKQSPKLTYAAIADLKQSYQNAGKDVLLVDAGDHVQGTAYGSMDEGASIIK
                     LMNAAGYDVATPGNHEFDYGMDRAKAIMKEADFPYLSCNWVDLRTTLRVLPSVKVFVRG
                     GRRIAFVGVTTPETFTKSTPAYFMDKAQRKYIYDIQGGEDGKKLYDAVQKAIDKAKLLA
                     DVVIGLGHLGVDPSSSPWTSEEVIAHTSGFDAFIDGHSHTVMENKQVQDASGKAVTLTQ
                     TGSYFANVGEMTIAADGTITTKLIPTHEGMDAGIAAMQTGWVNTVDDMLGEKIAVGDSD
                     FYVSDPATGKRRIRSAETNLGDFVADGIYTYFNEVEKLHCDVAIMNGGGIRADVPAGDW
                     TFKTCKQVSPFGNVACLMSVTGKQIQDALEFAARFAGEDGKENGGFLQVAGATYEIHTD
                     IPNTVQTDEKNVWIGSATGTPRVQNVKIYDKASGSYLPLDPGATYALAGMNYTLRNLGD
                     GFAMFDGAELIKDYVSEDYLVMSTYAMIFDGADAAGLPHLSSANSPLAAYPGYLLNYEQ
                     PYGAGRITIL"
     CDS             complement(6258..8030)
                     /locus_tag="ctg13_6"
                     /transl_table=11
                     /translation="MYYSSGNYEAFAHPKKPEGVDHKSAYIIGSGLAALTAACYLVRDG
                     QMKGEHVHVFEKNALAGGACDGYKYDIGYVMRGGREMDNHFEVMWDLLHSIPSLETEGA
                     SVLDEYYWLNKEDPNFSLCRATVNRGEDAHTDGKFGLSDKGAMEIMKLFFTPDEQLQDK
                     KITDFFDDEVLNTNFWMYWRTMFAFENWHSALEMKLYLKRYIHHIGGLPDFTALRFTRY
                     NQYESIILPMVRYLEGFGVQFHYNTKVTDVKFDIQKGRKLASSVTVEHAGETSNIDLTE
                     NDLLFITNGGCVESCTVGAQDKATGFDPTIQPGNGWDLWKKVAAQDPSFGHPEKFCSEP
                     ELSNWESATITTLDDKIPQYIRKICKRDPFSGHTVTGGIVTVKDSSWLLSWTLNRQQQF
                     KDQPKNQLCVWVYSLFSDKPGDYVKKPMRDCTGREICMEWLYHIGVPEDQIAELAEHSA
                     NTVPVMMPYIDAFFMPRAMGDRPDVVPEGAVNFAFLGQFAETARDTIFTTEYSMRTGME
                     AVYTLLNIDRGVPEVWGSTYDVRALIDATVKLRDGKKITDMDLPLIPRLALKEALKKIE
                     GTDLEKFLKEYNAI"
     CDS             complement(8395..8658)
                     /locus_tag="ctg13_7"
                     /transl_table=11
                     /translation="MSKEFSFPNKGTCSKQTNFVLNDDHTISSIEVVGGCNGNLKGICQ
                     LLTGMKAEDAIARLDGTLCGFRSTSCPDQIAKNLKKALEQMN"
     CDS             complement(8664..9524)
                     /locus_tag="ctg13_8"
                     /transl_table=11
                     /translation="MSCDLHIHSTCSDGAVPIERLASIAARTGLHAIALSDHDTLLSAQ
                     YAYAHTGQDGVELIPAVELTGYDFERQHRVHLLCYYPDVDCPALREHCAIMKERRNACA
                     LQSAKELEQLYPQFTTDLAWETTKASGVLFKSGLMQALELLGLTDGSIYGETYHKLFGW
                     NPRGIVLHSPEYLPVRQVLATAKASGGAVVFAHPTVYKSMPLLRELAAEGAVDGIEVYH
                     PSNSPEDSAECLALCKQYGLVATAGTDFHGRNHKHPHPIGTCTAPDEAAAQLRAIAEKR
                     KRERT"
     CDS             complement(9539..11815)
                     /locus_tag="ctg13_9"
                     /transl_table=11
                     /translation="MLDMIKCSTGGAYYARGEWVPADGNAPAALAAKGFDAAAVAAAKT
                     GTMAYNIMQAHNTSGDAENLKIKFDAMASHDITFVGIIQTARASGLEKFPIPYVLTNCH
                     NSLCAVGGTINEDDHRFGLSAAKKYGGIFVPPHMAVIHQYMRERFAGCGKMILGSDSHT
                     RYGALGTMAIGEGGGELAKQLLGRTYDVARPGVVAIYLTGSLPAGCGPHDVAIALVGKL
                     FKSGYVKNKVMEFVGPGIASLRQDTRNAIDAMTTETTCLSSIWETDEVTQRFLAVHGRA
                     ADYKKLTPADLAYYDGVVEVDLSAIRPMIALPMHPSNAFTIEELNANLEDILHACEQDV
                     QKLIGRKDVQLDLCSKIENGKLRVDQGVIAGCAGGLYDSIYEAASILKGHTGGCGDYAL
                     SVYPGSQPIMMELVRTGVIGELMASGATIRTAFCGPCFGAGDVPANGALSIRHTTRNFP
                     SREGSKPGSGQLAGVALMDARSIAATTANGGILTPATDIDYDPTVPEYQYDASSYDTRV
                     YQGFGKGDYDALLKFGPNIKDWPEIAPLGDNLLLKVASYITDPVTTTDELIPSGETSSY
                     RSNPLGLAEFTLSRKDPEYVSRAKAVQAEEAARRAGAGDAALLAKVNAVPGCEQLNWND
                     IQIASTIFAVKPGDGSAREQAASCQRVLGAGANIVTEYATKRYRSNLINWGMLPLQLAG
                     ATPFGLGDYVLIPNVREVLKGDLQSIKAYVLGDTVKEFELYMAPLTTDERQILADGCLI
                     NFYKH"
ORIGIN
        1 cgtttttatt ccaccagcaa agctggtggt tgtcgctcgc tcaagctacc caatatagag
       61 aacccggaag gtctgcggac tttccgggtt ctcttcttat aaaatcttta tcgcagcacc
      121 gagagttcct cgatgccata gcgctgcatc aggacgatgg ccgccggggt gatctcctcg
      181 ccgctgaccg ccacagggat ggcgggcggg caggacaccg tgggcatggc gcacacccgc
      241 cccagcgcct tgtgcaccgg gacacgcacc tgtgcgccca gcaccgcctg ccggatggta
      301 cagcgctgcg ccgcctgctg ctgcaaggcg gcaaactccc ctgcccggtt ctcggggcgg
      361 agcagcccgg caggcacagc agccaaaagc tgttccagca ccgtttgcag acgcgtgtag
      421 tcctgcggcg ggttttccgg ggtgaacatc agcaccacat agcgggggtc ggcatactcg
      481 cactccagct gtgcgcggcg caaagcatct gccagcgctg tgccggtgca gccaagggca
      541 gcggcgtcca gcgtaagctt catcggctcc tgctgtgccc cggcaactgc cagcggcacc
      601 gggcactgcc gcgccgctgc ggtcttattc aggctgcggc gcagaccttc cagcgccgcg
      661 cagcactgca ccagccgccg ggggtagtcc cctgccagca ccgcattgca ggcatccagc
      721 gactgcaaaa tgaggtaaga ggggctggta gagccgaaca gcgccagcgc cccccgcaca
      781 gccgcttcgt cctgcacagg ggcatcgtgc gccagatgca gatacgcgcc gccggtgacc
      841 accggcaggg tcttgtgggc agagtcgcag cacatggccg caccctgcgc gatggggtgg
      901 cagttctgcg gcaaaaagcg cagataggcg ccgtgggcgt tatccaccag caaaggcacg
      961 ccctgcgccc ggcagaccgc cgccagcgcc gggagttcct gcaccccgcc cagataatcc
     1021 gggctggtga cgtacacgcc aaagggggtg ttgccctgct gtgccatcgc gtgcaaagcc
     1081 ccggtcagcg cttcggctgt gacggggcag ctgcacagtg caccctctgc ctgcgcagac
     1141 ggccagagcc agcggatgtc aaaatccagc agcgccgccg catatagcag cgccttgtgg
     1201 gcgttgcggg cagccagcag caccgggcgc ttgccgcttt gcggtgcacc ctgcagcgcc
     1261 agaaacagca tggcgcggat gcactgggac gagccctcgg tactataata gctgtgcgcc
     1321 gtgccgaaca gccgggtggc gttggcttcg ctttcggcaa tgatgccctc cggcgcgtaa
     1381 agttcgtctg cgccgcagat ctcggtgata tccagcggct caaagcctaa aaggctctgc
     1441 cccttgtggc cgggcatatg cagccgggcg gtgccggact gtgcatagct gcgcacaaaa
     1501 tccacgatgg gggtggtcat gctcattcgc aggcttcgcc gtcggcgcag gcgttgcagg
     1561 tagagcccag ctcaatgggc acctcaatac ccttggcagc cagctcctga ttctcggcaa
     1621 ccttgatcat gatggcgcac tccatgcgct ttttgaacag ctcgcagccg tactcataca
     1681 cgccggtaat gctgccggtg gcatggtagg agttggcagc gcagccgccg gagcaataca
     1741 gctttgccca gcagtcctga cactccttac gggcgtaggc gttgcagtgc ttgaactcat
     1801 cccgcacggc ggtgttggta acgcccttcc agatatcgcc cagcaggtac ttggggtcgc
     1861 ccacgaactg gtggcagggg tacagatcgc cccagggggt aacagccatg tactcggtgc
     1921 cagagccgca gccggagatg cgcttataga tgcaggggcc gccggtcagg tcgatcatgt
     1981 agtggtagaa ggtaaagcct ctgccctcgc ggtcgcgctt gatcatctcc ttggcaagga
     2041 tctcgtactg ctccttcagg atgggcaggt cggcctcagt cagggcgctg gggtcgctgg
     2101 ggtcgcagac caccggttcc atgctcagct cggtaaagcc gaggtctgcc atgtggaaga
     2161 tatcgttggt aaagtcggtg ttaaagtggg tataggtgcc gcgcatatag tagttcttgt
     2221 cgccgcgctt cttgacgaac tcctggaact tgggcacgat gcggtcgtag ctgccgttgc
     2281 ctgcgcagtc cacgcggaag cggtcgttga cctccttgcg gccatccaga ctcagcacca
     2341 cgttgtggca ctccttgttg cagaagtcga taacgtcgtc atcaatgagc acaccgttgg
     2401 tggtcatggt aaagcggaag ttcttgttat ggatcttttc ctgctcacgg cagtaggcca
     2461 ccagcttttt gaccatctca aagttcatca gcggctcgcc gccaaagaag tccacttcca
     2521 gattgcggcg ggtgccgctg ttctcgatga ggaagtccat ggcgcgcttg cccacctcaa
     2581 agctcatcag ggcgcggtcg ccatggtagc gcccctgcga ggcaaagcag taagagcagc
     2641 tcaggttgca gctatgggca acgtgcaggc acagcgcctt taccacggtg ttgcggttct
     2701 tgaagtcgaa ggccatgtcc ttatagacat ccgggctcca cagcttgccg ttttccttca
     2761 ggctggtcac gtcgtcgatg cactggcgca gatcctcctc ggtcacgtcc gggcggctgc
     2821 cgtattttgc cagcatggcg gcaacgatct cgtctgcggt atgctccggg tacatggcga
     2881 tgacatcgta ggccacctcg tccacaacgt gcaccgagcc gctgcaggtg tccagcacga
     2941 tgttataacc gttcaattga tactgatgta ccattttaca ctccattcca gattacacaa
     3001 aaaaatgccg cccggcaaag gcggcatagg gtttgcaaaa attacttgtt gctgttctcg
     3061 cactgctggt tagccacgcc gcaggaggtc ttgcaggcgg actggcagga agtctggcac
     3121 tcgccgcagc caccggtctt aacgctcttg gtcaggtcac gagtagcaat agtcttaata
     3181 cgctccatga tagaaacctc tctaactctc aaaaatttat cgcgccggac atagttccgg
     3241 tacgctttta tcttgtaata ggatatcacg cagcgcgcct tttgtcaaga ttttttcgct
     3301 aaggcaatac cgcataattc taggtgccga tacggcgagt gaggtgcggc agatgctaag
     3361 ccaaaagcgc agataatact ttgtgtatta tcgagcattt tggcaacgca gatgccgtgc
     3421 cgcaaccgcc ggagtggtgc ttaagccgta aggcgggaat tgtgcggtgt tgccctaagc
     3481 cttttcaccc gcccatgggc tggtagcggg taagcaccgt gtgcagcccc agctcccggg
     3541 cgcgcgccag taagtaccgg taacgacaca gcagcgcctg ccgctcgtag atgcgctgct
     3601 cgatcaggtc cgtatccacc tccatatcaa acatcatctc gttgcgcttc aaacagaaca
     3661 ggcattcctt cagctcctcc tccagttccg gatggtagcg ctcgtgctcg gtatcccgcg
     3721 ggacgcgggg cgaaagcaag gtctgggcgt tttgtgtggt tcgttccggc ataggcatcc
     3781 tccttctggt gctttgtaag gttttgtacc ttccagtata ggcggtgcgg tgcgcagaac
     3841 ctgccgaagc gtggcagcgc tccggcatag attatccggc gctgctgcgg cattttccaa
     3901 aaaagtacaa cttttttcaa aaatatgctt gacaaccccg ggcttttccc gtataatagc
     3961 acacgttgag cggctcaccc cgcaaaacac aacagaatat tggggatttg catagtggta
     4021 gtgcggtaga ctctgactct acttgtggga gttcgattct ctcatcccca accagaacaa
     4081 agccatctga ggaaactcag gtggcttttc tgtttgtatg attccgcgcg gaaaaactat
     4141 tatagataga gcgaacccgg aaagtccaca ggactttccg ggttcgcctt ttcacgggaa
     4201 atataaattt acagaatggt aatgcggcct gcgccgtagg gctgctcgta gttgagcagg
     4261 tagccggggt atgcggccag cgggctattg gcgctggaca ggtgcggcag acccgcagca
     4321 tctgcgccgt caaaaatcat agcgtaggta gacatcacca gataatcctc ggacacatag
     4381 tccttgatca gctctgcgcc gtcaaacatg gcaaagccat cgcccagatt gcgcagggtg
     4441 tagttcatgc cggccagtgc gtaagtagca cccgggtcca gcggcagata gctgccggag
     4501 gccttatcgt agatcttcac gttctgcaca cgcggggtgc cggtggcgct gccgatccag
     4561 acgttcttct cgtcggtctg cacagtgttg gggatatcgg tgtggatctc gtaggtagca
     4621 ccggccacct gcaggaagcc gccgttctcc ttgccgtcct cgcctgcaaa gcgggctgca
     4681 aactccaatg cgtcctggat ctgcttgccg gtgaccgaca tcaggcaggc cacgttgcca
     4741 aaggggctga cctgcttgca ggtcttgaag gtccagtcgc ctgcgggcac atcggcgcgg
     4801 atgccgccgc cgttcatgat ggccacatca cagtgcagct tttccacctc gttgaagtag
     4861 gtgtagatgc cgtcagccac aaagtcgccg aggttggtct cggcagagcg gatgcggcgc
     4921 ttgccggtgg cggggtcaga gacgtagaaa tcactgtcgc ccacagcgat cttctcgccc
     4981 agcatatcgt ccacggtgtt cacccagcca gtctgcatgg cagcgatgcc tgcatccatg
     5041 ccttcgtggg tggggatgag tttggtggta atggtgccgt ccgcagcgat ggtcatctcg
     5101 ccaacgttgg caaagtaaga accggtctgg gtcagggtga cagccttgcc ggaagcatcc
     5161 tgcacctgct tgttctccat tacggtatgg gagtggccgt cgataaaggc gtcaaagccg
     5221 ctggtgtggg caatgacttc ctcactggtc cacggagagg aagaggggtc tacgcccaga
     5281 tgacccagac cgatgaccac gtctgccaga agctttgcct tatcaatggc cttctgcacg
     5341 gcatcgtaga gctttttgcc gtcctcgccg ccctgaatat cgtagatgta cttgcgctgt
     5401 gccttatcca taaagtaggc cggggtggac ttggtaaagg tctcgggggt ggtcacaccc
     5461 acaaaggcga tgcgtctgcc gccgcgcaca aacaccttga cggagggcag cacccgcagc
     5521 gtagtgcgca ggtctaccca gttgcaggac aggtacggga agtcggcttc cttcatgatg
     5581 gccttggcac ggtccatgcc gtagtcaaac tcgtggttgc cgggggtggc gacatcgtaa
     5641 ccggcagcgt tcatcagctt gatgatggaa gcaccctcgt ccatggagcc gtaggcagtg
     5701 ccctgcacat ggtcgcctgc atccaccagc agcacatcct tgccggcatt ctgatagctc
     5761 tgcttcaggt cggcaatagc ggcgtaggtc aacttggggc tctgcttgtc gatgtaggta
     5821 tggacatcgt tggtgtacag gatggtaacg tcagacttgt caccatacca gcaggccgat
     5881 gcggcaggcg caccgatggc catggatgca gcggcagcgg tcacaccagc agcctttaaa
     5941 aagcagcgac gggaaataag ttgtttcaca ggaaaacgac ctccttttat ttttggcgta
     6001 tcgcatttga ggcaggctct tccctcctgc cctttcaata gctctagcat agcacagaac
     6061 gccgccgcaa acaagccaaa atcattcttt tggcacaaat tattttcacg ttccgcttta
     6121 ttttaacata tattgtacca tttttacaca aattctatgc aaaaaagacc ttcccgtgcc
     6181 ctgtcgcaga gcagcggaga ggtctttttt aggggggtgt tgacccgttg ccggatctat
     6241 cggaggagag ggaaatatca gatagcgtta tactccttga ggaacttctc aaggtcggtg
     6301 ccctcgatct tcttcaaagc ttccttcaga gccagacgcg ggatcagcgg cagatccatg
     6361 tcggtgatct tcttgccgtc gcgcagcttc acggtggcat cgatcagggc gcgcacatca
     6421 taggtgctgc cccagacctc aggcacgccg cggtcaatgt tcagcagggt atacacagcc
     6481 tccataccgg tgcgcatgga gtactcggtg gtgaagatgg tatcgcgggc ggtctcggca
     6541 aactgaccaa ggaaggcgaa gttcacagca ccctcgggca caacatcggg acggtcgccc
     6601 atggcacggg gcatgaagaa ggcgtcgata taaggcatca tcacaggcac ggtgtttgcg
     6661 ctgtgctctg ccagttccgc gatctgatcc tcgggcacac cgatgtggta cagccactcc
     6721 atgcagatct cgcggccggt gcagtcgcgc atgggcttct tgacgtaatc gccgggctta
     6781 tcgctgaaca ggctgtacac ccagacgcac agctggttct tgggctgatc cttgaactgc
     6841 tgctgacggt tcagcgtcca gctgagcagc cagctggagt ccttgacggt gacgatgccg
     6901 ccggtgacgg tatggccgct gaaggggtcg cgcttgcaga tcttgcggat atactgaggg
     6961 atcttgtcgt ccagcgtggt gatggtggca ctctcccagt tgctcagctc cggctcggag
     7021 cagaactttt ccgggtgacc gaaggaggga tcctgtgcgg cgaccttctt ccacagatcc
     7081 cagccgttgc cgggctggat ggtggggtca aagccggtgg ccttatcctg tgcacccacg
     7141 gtgcagcttt ccacacagcc gccgttggtg atgaacagca gatcgttctc ggtcaggtcg
     7201 atgttagaag tctcgcccgc gtgctccacg gtgacagagc ttgccagctt gcggcccttc
     7261 tggatgtcga acttcacatc cgtgaccttg gtgttgtagt ggaactgcac gccaaagcct
     7321 tccagatagc gcaccatggg caggatgatg gactcgtact ggttatagcg ggtaaagcgc
     7381 agggcggtaa agtccggcag accgccgatg tggtggatat agcgcttgag gtacagcttc
     7441 atctccagag cgctgtgcca gttctcgaag gcgaacatgg tgcgccagta catccagaag
     7501 ttggtgttga gcacctcgtc atcgaagaaa tcggtgatct ttttatcctg cagctgctcg
     7561 tccggggtaa agaacagctt catgatctcc atggcaccct tatcggacag gccgaatttg
     7621 ccatcggtgt gagcatcctc gccgcggttg acggtggcac ggcacaagga aaagttggga
     7681 tcctccttgt tcagccagta gtactcgtcc agcacactgg caccctcggt ctccagagac
     7741 gggatggagt gcagcagatc ccacataact tcgaagtggt tatccatctc gcggccgccg
     7801 cgcatcacat agccgatatc gtacttgtag ccatcgcagg cgccgccggc cagtgcgttc
     7861 ttttcaaaca catggacgtg ctcgcccttc atctggccgt cgcgcaccag atagcaggca
     7921 gcggtcaggg ctgccagacc ggagccgatg atataagcgg atttatgatc cacgccctcc
     7981 ggctttttgg ggtgtgcaaa agcttcataa ttgccactgg aatagtacat aaaaaagcct
     8041 ccctgcttca aaaatatctt ttcacagcct tcatcgtgct gttctctatg gcaacagtat
     8101 accccgcaaa gtgaaccgga acaacaaaca aactttgccc ggtgtataga ttttttacat
     8161 ccgccctcat ttgctggaaa tgcgtacaaa ttgtgacata aagcgcagcg caaaatcatt
     8221 taaaacactc cctcaaaaga gcaatgccgg gcagcccgca ggctgtccgg cattgctcta
     8281 attcaaaata attttccgct attcatgccc agagcatagc ggcgggcatt caaaatcgtc
     8341 ctgcgcaaaa agagccgcca cacaaggttc tgtgcagcgg ctctccggtg gattttagtt
     8401 catctgttcc agagcctttt tcaggttctt tgcgatctgg tccgggcagc tggtgctgcg
     8461 gaagccgcac agcgtgccgt ccagacgggc aatggcgtcc tctgccttca tgccggtaag
     8521 cagctggcag atgcccttca ggttgccgtt gcagccgccg acgacctcaa tggaagaaat
     8581 agtgtggtca tcgttcagca caaagttggt ctgcttggag caggtaccct tgttcgggaa
     8641 ggaaaattcc ttgctcatag tctttacgtc ctctctcttt tacgtttttc ggcgatggcg
     8701 cgcagctgcg ctgcggcttc gtctggtgcg gtgcaggtgc cgatggggtg ggggtgcttg
     8761 tggttgcggc catggaagtc cgtgcccgca gtagccacaa ggccgtactg tttgcacagg
     8821 gcaaggcact cggcgctgtc ctccgggctg ttgctgggat ggtacacttc tatgccgtcc
     8881 actgcgccct ctgccgccag ctcccgcagc aggggcatac ttttatacac cgtggggtgg
     8941 gcaaacacca ccgcgccgcc gcttgccttg gcggtagcca gcacctgccg caccggcaga
     9001 tactccggcg agtgcagcac gatgccccgg gggttccacc cgaacagctt gtggtaggtc
     9061 tcgccgtaga tgctgccatc ggtcaggccc agcagttcca gcgcctgcat cagcccgctt
     9121 ttgaacagca ccccgcttgc ctttgtggtc tcccatgcaa ggtcggtggt aaactgcggg
     9181 tacagctgtt ccagctcctt tgcgctctgc aaagcgcagg cgttgcggcg ctccttcatg
     9241 atggcgcagt gctcccgcag cgccgggcag tccacgtccg ggtagtagca cagcagatgc
     9301 acccggtgct gccgctcaaa gtcgtagccg gtcagctcca cggcgggaat cagctctacc
     9361 ccgtcctgcc cggtgtgggc ataggcgtac tgagcgctga gcagggtgtc gtggtccgaa
     9421 agggcgatgg cgtgcagccc ggtgcgggcg gcgatggacg ccagccgctc gatgggcaca
     9481 gcaccgtcgg agcaggtgga atggatatgc aggtcacagg acatagcggg ttacttcctt
     9541 agtgcttata gaaattgatc aggcaaccgt cagccaggat ctggcgctcg tcggtggtga
     9601 gcggagccat gtacagctca aactccttga cggtatcgcc cagaacgtag gccttgatgc
     9661 tctgcaggtc gcccttgagt acttcccgca cattggggat gagcacatag tcccccagac
     9721 caaagggggt ggcacctgcc agctgcaggg gcagcatgcc ccagttgatc aggttggagc
     9781 ggtaacgctt agtagcgtac tcggtaacga tattggcacc ggcacccagc acacgctggc
     9841 agctggcggc ctgctcacgg gcagagccgt cgccgggctt gaccgcaaag atggtagaag
     9901 cgatctggat atcgttccag ttcagctgtt cgcagccggg cacggcgttc acctttgcca
     9961 gcagggcagc gtcccctgca ccggcgcggc gggcagcttc ctcggcctgc acggccttgg
    10021 cgcgactcac atactccggg tccttgcggc tgagggtgaa ctcagccaga cccagcggat
    10081 tggaacggta agaggacgtc tcgccggagg ggatcagctc atcggtggtg gtgacggggt
    10141 ctgtgatata agaagccacc ttcagcagca ggttgtcgcc cagcggtgcg atctccggcc
    10201 agtccttgat gttggggcca aatttgagca gggcatcgta atcgcccttg ccaaagccct
    10261 gatacacgcg ggtgtcgtag ctggaagcat cgtactggta ctccggcacg gtgggatcat
    10321 aatcaatgtc ggtggcgggg gtcagaatgc cgccgtttgc ggtggtggct gcaatgctgc
    10381 gggcatccat cagtgccaca ccggccagct ggccgctgcc gggcttggag ccctcgcggc
    10441 tggggaagtt gcgggtggtg tgacggatgg acagtgcgcc gttggcgggc acatcgcctg
    10501 cgccgaagca ggggccgcag aaggcggtgc ggatggtagc accgctggcc atcaactcgc
    10561 cgatgacgcc ggtgcgcacc agttccatca tgatgggctg gctgccgggg taaacgctca
    10621 gggcgtagtc gccgcagccg ccggtatgac ccttgaggat ggaagcagcc tcgtagatgc
    10681 tgtcgtacag accgcctgcg cagcctgcaa tgacgccctg atccacacgc agcttgccgt
    10741 tttcgatctt gctgcacaga tccagctgca cgtccttgcg gccgatcagc ttctgcacat
    10801 cctgttcgca ggcgtggagg atgtcctcca ggtttgcgtt cagctcctca atggtaaagg
    10861 cattggaggg gtgcatgggc agggcgatca tgggacggat ggcagaaaga tccacctcca
    10921 ccacgccatc gtagtaggca aggtcagccg gtgtcagctt tttatagtct gctgcacggc
    10981 catgcactgc cagaaaacgc tgagtgactt cgtcggtctc ccagatggag gacagacagg
    11041 tggtctcggt ggtcatggca tcaatggcgt tgcgggtatc ctgccgcagg gaggcaatgc
    11101 cggggcccac gaactccatg accttgtttt tgacgtagcc gctcttgaac agcttgccca
    11161 caagggcaat ggctacatcg tgggggccgc agcccgccgg cagactgccg gtcaggtaga
    11221 tggccaccac gcccgggcgg gcaacatcat aggtgcggcc cagcagctgc tttgccagtt
    11281 cgccgccgcc ttcaccgata gccatggtgc ccagtgcgcc gtagcgtgtg tgggagtccg
    11341 agccaaggat cattttgccg cagccggcaa agcgctcgcg catatactgg tggatgactg
    11401 ccatgtgcgg gggcacaaag ataccgccgt actttttggc agcggacagg ccaaagcggt
    11461 ggtcgtcctc gttgatggtg ccgcccacag cgcacaggct gttgtggcag ttggtaagca
    11521 cataaggaat gggaaacttt tccagcccgg aagcacgggc ggtctggatg atgcccacaa
    11581 aggtgatgtc atggcttgcc atggcatcaa acttgatctt caggttctcg gcatcgccgc
    11641 tggtgttgtg tgcctgcata atattgtagg ccatggtacc ggtcttagcc gcggcaacgg
    11701 cagcggcatc aaagcccttt gctgccagtg ctgcgggtgc attgccatct gcgggcaccc
    11761 actctccgcg cgcatagtac gcaccgccag tgctgcattt gatcatatcc aacatctcga
    11821 ttcgcctctc tttttgtatt ttcccgcccg ccgcaattgc gggcattgcc ccggcagtgc
    11881 ggctattcat cccgaaaaca gccgtcccct tagccttcac cccttggggg ggaagccatt
    11941 aagcaaacca gcttttcaaa gacttataac ccctgccctg ttacggcaaa agccgtattt
    12001 aatttttatt atagcatgaa agggcgaaaa gaaaaagcat tttttatgaa cccttactgc
    12061 acctttgcgg cggcttcctg ctgcttttcc ttttgcagtc tgcggaacac cacaaaatag
    12121 gccgggatca ggaagaagca ggcaaagagc catgccaccg ggcttgcgat gcaggcggca
    12181 aagtagcccc acagcggcac gaaccagaag cccaccatgg cgcgggcgat catttcagcc
    12241 acaccggcaa acatggcaag gccggagtgt cccagaccct gaatggtgta gcggtagatg
    12301 ataagcactg ccagcgggat gtagaacaca ctgttccaga agatgaagtc ctgcgcattg
    12361 gccataatgg cggtctcgcc tgcgtccaaa aacaggccga tcaggggctt gtccagcacg
    12421 cgcaggatga ggaaggaggc cacgctgtac acgcagccga tgcccagtgc ggtgttcacg
    12481 ccgcggttca cgcggcccag atccttcgcg cccatattct ggctggtgta ggtggtcatg
    12541 gcggtgccga tgctctccag cggcacgctg aggaactgcg cagccttgcc gccggcggtc
    12601 tgcgcggcta cgatatcgct gcccagaccg ttcaccgcgc cctgcagcac cacgctgccg
    12661 atggcagtaa tactgcactg cagacccatg gggaggccca tggcgcaaag ctttgcgcag
    12721 tgcggagcgc tgatgcgccc ttcttcctta ttccagcgca gttccgggta gtggcgcatg
    12781 atgtaaataa ggctgccgat gcctgccaca gcctgactga acacggtggc aaaagccgcg
    12841 ccgaacacgc ccatgttgaa caggatgatg caggcaaggt ccagcccgat gttcagcacg
    12901 ctggccacca gcaggaaata cagcgggcgc ttgctgtcgc ccagtgcacg catcagggcg
    12961 ctggtcacat tataaagcag cgtgaagggg atgcctgcaa aaatggtgcg gatatagata
    13021 tccgcaaggt cgatgatatc ggccggggtg ttcgtccaca ccagcaccag atgggtcatt
    13081 gccaccgtaa cgatggtaag caccgtggca aaggcgatgg acagccacac ggtattggcg
    13141 gtgtagcggc gcatctcgtg gtggtcgtgg gcgccgaagg tccatgag
//
