LOCUS       c00004_gnlPro..        24613 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GEGBNCDM_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 19:11:31
            Original ID  :: gnl|Prokka|GEGBNCDM_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 137476
            Orig. end    :: 162089
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24613
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[147476:152089]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14613
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24613
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24613
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="2"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             1711..3471
                     /locus_tag="ctg4_124"
                     /transl_table=11
                     /translation="LYSETTLQKASEQPIYNLNNLIMEWIFNQLRERPELAIFLTIFLG
                     FWLGKLRIGKFTLGTVTSVLLVGVLVGQLNIAVPGPIKSVFFLLFLFAVGYKVGPQFFR
                     GLKKDGLPQVGFAVLMCISVLLVTWLLALMMGYNAGEAAGLLAGSQTISAVIGVAEDTM
                     ANMGLDEAQRQSYVNIIPVSYAVTYIFGTAGSAWVLSSIGPKMLGGLEKVKAACKELEA
                     KMGSSLADEPGFMPAARPVTFRAYRVENEWFKNGKRVIDLEVYFRQHDKRLFVERLRKS
                     GVVVEVSMNIQIEPGDEVVLSGRREYIIGEESWIGPEVQDAQLLDFPAEKLPVTITRKT
                     VAGKTVAVIRREKFMHGVSIRSIKRAGISIPVLAQTVVDAGDVIEVVGTRQEVEAAAKR
                     LGYIDRPTNQTDMIFVGLGILVGGLFGALSVHIGGIPISLSTSGGALIAGLFFGWLRSK
                     HPTFGRIPEPSQWVLNNVGLNMFIAVVGISAGPSFVQGFHDVGISLFLVGAAATALPLI
                     IGLLLARYVFKFHPALALGVCAGARTTTAALGAVQDAVESETPALGYTVTYAVGNTLLI
                     IWGVVIVLLI"
     CDS             3748..5382
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_125"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-21, bitscore:
                     70.2, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.0015, bitscore:
                     11.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKLLEKKMESISPFELKNRLIDMADESLKKTARTMLNAGRGNP
                     NWIATAPREAFFLLGSFGLEECRRIMDLPEGIAGIPEKKGIASRFEAFLKKNNNVPGAK
                     LLEQTYNYLLMQHAADPDSLVHEWAESIVGDQYPVPDRILHFTEILVQDYLSQEMCDNR
                     PPRGAYDLFATEGGTAAMCYIFDSLQENFLLNKGDGIVLMVPAFTPYIEIPQLSRYQFR
                     VTKIHANRMNSEGMHLWQYSDEDIDRLKSPKIKALFVTNPSNPPSYTLSPDTMARIVSI
                     VRNDNPNLMIITDDVYGTFSPHFRSFMAEIPYNTLCVYSFSKYFGATGWRNAVIALHEF
                     NLFDKLIAKLPKEKREILHHRYSTLTLEPEKLKFIDRMVADSRQVALNHTAGLSLPQQM
                     QMGLFAAFALLDKENKYKQKMQEIIHRRLHALWENTGFTLTEDPLRVGYYTEIDMLVWA
                     KKFYGDDFVEYLKRTYSPLNVVFRLAKETSLVLLNGGGFDGPEWSVRASLANLDEKDYA
                     TIGRGIKKILEEYAKEFFKNGKAKGKN"
     CDS             complement(5416..6729)
                     /locus_tag="ctg4_126"
                     /transl_table=11
                     /translation="VRIKFFFFILVLFLLGLGGMLVYLLSGKPLLYLYVLEGLIGFILI
                     YLIVFYNKIVKPMNTIGSGMELLREQDFSSRLSRVGQYEADRIVNIFNRMMEQLKNERL
                     RMREQNHFLDLLIQASPMGVIILTMDDEVSQLNPMAVKMLGVRMEEAMAKRLDQMDSPL
                     AAELSSIPKDETAVVRLNDANIYKCTHSSFIDRGFKHPFFLIERMTEEVMRAEKRAYEK
                     VIRMIAHEVNNTTAGITSTLDTVEQALSTEDDMEDICDVMRVCTERCFSMSRFITRFAD
                     VVKIPEPTLVPVQLNELVSMCKRFMEGMCNDRNIELRLECDPEVGMVRMDASLFEQVLV
                     NIIKNAAESIEGDAGENGQQGEIIVRTTAPASVEVVDNGPGISKETEAKLFSPFFSTKP
                     NGQGIGLVFIREVLSRHGCTFSLRTYNDGLTRFRILFN"
     CDS             complement(6720..8081)
                     /locus_tag="ctg4_127"
                     /transl_table=11
                     /translation="MILIIDDDSAVRSSLSFMLKRAGYEVKTAPGPREAMDIVRAEAPA
                     LILMDMNFTLSTTGEEGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITK
                     PWNNAALLQRIETALELTAAPKEVPEEQTTALNRSHIIGKSKGLMEVLNTVARIARTNA
                     SVLITGESGTGKELIAEAIHINSQRVKQPFVKVNLGGISQSLFESEMFGHKKGAFTDAS
                     ADRIGRFEMANKGTIFLDEIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKVDVRVVSAT
                     NADLRKMVSERTFREDLFYRINLITVKLPSLRERREDIPLLARHFADRQAEVNGLPRTD
                     FSADALNFLSRLPYPGNIRELKNLVERTILVSGKPVLDAADFDAQYLRHDEPAKAAEGT
                     SFAGMTLDEIERQTILQALEQHKGNLSQVAVSLGISRAALYRRLEKYNIQVPCA"
     CDS             complement(8225..9712)
                     /locus_tag="ctg4_128"
                     /transl_table=11
                     /translation="MKKNILLAVCFLMPLATMAQNDTLGHERNITLSEAIVLARTQSVD
                     AAVALNELKTAYWEYRTFRADLLPEVNFTGTLPNYNKSYSTYQNSDGSYSFVRNNTLGL
                     SGQLSVDQNIWFTGGKLSLTSSLDYLKQLGSGGAKQFMSVPVSLELTQPVFGVNTLKWN
                     RRIEPVRYAEAKAEFISATEEVTMKTITYFFELLLAKESLATAMQNKTNADRLYEVAIA
                     KRKMGQISENDLLQLKLNSLQGKADVTEAESNLNAKMFQLRSFLGVSEQESLNPVLPAT
                     VPDIKMEYDRVLNKALERNSFAQNIRRRQLEADYEVATARGNLRSIDLFASVGYTGQNH
                     EFSSAYRDLLDNQIVQVGVKIPILDWGKRRGKVRVAKSNREVVLSRIRQEQMDFNQDIF
                     LLVANFNNQAQQLDIAEEADVIAEKRYKTSVETFMIGKISTLDLNDAQNSKDEARQKHI
                     SELYYYWYYFYQLRSLTLWDFERDTELEADFEEVVRG"
     CDS             10001..10417
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_129"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.5e-25, bitscore:
                     82.2, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMHHLAFAVEDGVAGALAEVEEKGIRL
                     IDKAPRKGAEGLNIAFLHPKSTLGVLTELCEKPE"
     CDS             10476..12029
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_130"
                     /sec_met_domain="CT_Btheta (E-value: 1.6e-290, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12061..12993
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_131"
                     /sec_met_domain="OAD_gamma (E-value: 1.3e-16, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             13017..13451
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_132"
                     /sec_met_domain="Biotin_lipoyl (E-value: 6.6e-21, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             13453..14613
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_133"
                     /sec_met_domain="OAD_beta (E-value: 5.8e-152, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14786..16138
                     /locus_tag="ctg4_134"
                     /transl_table=11
                     /translation="MRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALMLIDQET
                     PTVPLLYQKGKALKGLGNNLEALSVFQEVVAQDSLNPRAYIEAAECCKSLAKYSEALDY
                     YQNALHINPDNKYARIQYISLLMNMKRYRESLKESNLLAERDSSAYVLHLRAESMGQVY
                     DNTEIMHVIDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYEDAISITEKYRSIDSTNVLV
                     NRINAQAYCLNKDYPKAIERYEQLLQEKDSSFQTCFYAGISYYALEDFYPAHDLLERAL
                     KDDNTNINVLYYLGRACSKTSWKEDGVTYLETAVSLAMPSDSVMSRLYVGLADCYKMAF
                     QYTDQANTLLTQYEKYDRQKHKLLYDAAFIYYYYLKDVSKAERYLTAYLKTRPKNSKDK
                     VQEVDADGVPIIGEDNRYNAAENWLKDIREKRKKEDFFKGKVDTASVTPIK"
     CDS             16249..18099
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_135"
                     /sec_met_domain="Alpha-amylase (E-value: 4.4e-63, bitscore:
                     207.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVFLILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKE
                     YELKARNKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMAEYKIDRKDPNARHGG
                     DLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKAHARGIKIVMDMIFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPY
                     TSQYDADQMNDGWFVPSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKI
                     NTAKNEQTETWFKGLDRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGDNLPMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNE
                     CYDFYKTILNWRKGNDVIAKGNMVQFMVQNGVYAYARQYEGKTIFVMLNGTDAETTVPL
                     KFYKEILKNSKQGKDILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(18570..19580)
                     /locus_tag="ctg4_136"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINKYGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSENKLAQLD"
     CDS             complement(19863..20870)
                     /locus_tag="ctg4_137"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTVHDAG
                     KNDHEFLPDGSYQWTVKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLSTPFEGDTVHLTRGFLI
                     VDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKALKDSLMRSDKKLKLIVMGDMNDD
                     PMDESMEVLGARKYPKQVKKGEFYNPWWETLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTIIYLKN"
     CDS             21059..21310
                     /locus_tag="ctg4_138"
                     /transl_table=11
                     /translation="MKKGIHPENYRPVVFKDMSNGDVFLSRSTCNTKETIEFEGETYPL
                     VKLEISSTSHPFYTGKSKLVDTAGRVDKFMSRYGNRKK"
     CDS             21493..23019
                     /locus_tag="ctg4_139"
                     /transl_table=11
                     /translation="MKRLATLFILTILVATAGFAKPKKYKDLSGNIAVKGELTKEYRQS
                     PAGTPVIIRRVVKMKNPGESSNNICYAVEMNGIQETIPLNEMGHIAISAPQTDREFWQQ
                     IYLKNHLYEYFSDRGYKHKLRQEIDEECLEYLDKLNEIAYQEDYIVSYVQGVFSKLNAT
                     TIDSNRGESLNIRIIQSPEPDAFMLPNGSMVISTGLLCTLDSEDELAAVIACELGHFVL
                     DHQVNNIYRAERRAKRAAFWADVFATTASAALDVAYWDDNEDAYAVSLVADIGAIASLL
                     SIPATDRLGMKYKTSQEISSDRLARQLLAFKGYNPDGIASALGKIIGYYNLHQRNKDIP
                     RYGSIGNLQKRIEKAGESHSLSARPYLRTTSDVVSFNASMNYANKRYKETARLIRKNID
                     NRLATDNDYIILVKAEMALSNTEEVNNRCLAMLDKAQEMAGTSPNLDIYKQKILLLMRM
                     NKQAQAADILKEYITLLSAYEGQGIEGTEKEWTNKEIGWANQMLDRISRI"
     CDS             complement(23111..24199)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_140"
                     /sec_met_domain="GCV_T (E-value: 9.5e-96, bitscore: 313.3,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 2e-24, bitscore: 78.7,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTPFTEKHISLGAKMHEFAGYNMPIEYSGIIDEHLTVCQGVGV
                     FDVSHMGEFWVKGPHALDFLQKVTSNNVAALTPGKVQYTCFPNDNGGIVDDLLVYHYEP
                     EKYLLVVNASNIEKDWNWCVSHNTEGAELENASDHMAQLAVQGPKAIQTLQKLTSINLS
                     DLPYYTFTHGEFAGEKDVIISNTGYTGAGGFELYFYPEAAMKIWDAVFEAGAEFGIKPV
                     GLGARDTLRLEMGFCLYGNDLDDTTSPIEAGLGWITKFVEGKNFTNRPMLEKQKAEGTT
                     RKLVGFEMIDRGIPRHGYELYSTDGTAIGVVTSGTMSPTRKIGIGMGYIRPEYSKVGTE
                     ICIDMRGRKLKAVVVKPPFRKQ"
ORIGIN
        1 gaaattcatt ggcatattcc ttcttcctat gaaaagaata ttccagttcg gcgagtccct
       61 ttacacgatg gtcgcgaaaa ccgtatgcca tatagcccct gccgaacaaa tgcggattga
      121 gccatgccgt cgtcataccg ccggcacgca agcgcacccc ttccagtgta tttccgctga
      181 tagtggtatt catcataccg atatagaaca aaggttcttt ttccttcgga gcgggaatat
      241 accccgtgaa cagcaccttc aacactttct ccgtccagaa ataaacggga tagctgcgca
      301 actgggccat catcttgtcc accgaagtct ctttcttgct gacctccacc tggcggttgg
      361 catcccaata tgcttccgaa tagccggaag ccgatgtctc ttcaatcacc ttttccgctt
      421 ttcggaaagc ctgcagagcc ttgtcatccg gttcatactg ataatttctg taatacacat
      481 cccgcttggc ataaataccg tcactattgt ccaccaactt gaactccgta gtgatactct
      541 cattgagcaa ctgcctcgta ccgtcctccg cgcggtcaaa attctgttca atcttcatgt
      601 agtccacaaa gttcagattt attttctgag gaaagttcat gacggcacgc tttacaaaat
      661 aggtactgtc cagcatgacg tataaatgtc ccgtaaaacc gaacgactcg gagttgaaag
      721 ggacaaatgt caagtcaaca caaggctttc cggcaacggt aagcgtatcc atcagataat
      781 atttgtagaa agacggccca agggaggaaa gcggactgac aaacttattg gtgaacaagg
      841 tgatgttgtt ctcataaagg tctacatcgg tcatggtgac actgatagcc tgctccatac
      901 cctgctggga aagcatttcg tccactcctg cctgcctgcg ggcggtgacc cactgtttcc
      961 ggctatgcgg agacttgcgg taatagtctg tggcaagcaa ctcacggttg gagatggcca
     1021 gtaccggcct gccggtaacg gcagaggtat cgacataatc cgtcagaaac ttgaacttac
     1081 ggtaaagcca cttctgttgc ttcaagctgt cgaagttatt gatggcaaaa gtcatctttt
     1141 catagcggtc acgtttccag aagtcgcgtt cgtcgggcga gtagtcatcc cgatgctcta
     1201 tcatcttgcg tacaaactcc actgcgggat tatccttttt cttataccgt tcacgtttcg
     1261 gcttcaccac cacctcatcc agtgcataag tggctggcga aagggctata ttgaacttag
     1321 aagactttgc aggatgaatc agccggacat attcattata tcccacggcc gaaatgacca
     1381 gcgtggcctc cgggcgatag gtcttgaagg aaaaacggcc gttattgtcc gtcatccctc
     1441 cctccgtagt tcctttcaga taaactgacg tataaggcaa cggctccttc gtcaacgaat
     1501 cggtgacaac gccttgcacc atatattgtg ctctcaatgg aagagtaacc agctggataa
     1561 gcagaaatac cctaaaaaac aacttcatac cttgttttac ctaatttgga tggcaaaggt
     1621 acggaagaaa actttttctt aaagttcggt tttacggaat aaatgttcta aaaaactcct
     1681 tttgtataaa acacttcccg ttaaaagccg ttgtatagcg aaacgacgct ccagaaagca
     1741 tcggaacaac caatatataa cctaaacaac ttgattatgg aatggatttt caaccagctc
     1801 agggaacgcc ccgaacttgc cattttcctc actatattcc tgggattctg gctggggaaa
     1861 ctgcgtatcg gtaagtttac gctgggcaca gtgaccagtg tactgcttgt aggcgtactg
     1921 gtagggcaac tgaacatagc cgtaccgggt ccgataaagt cggtattttt tctgcttttc
     1981 ctttttgccg tgggctataa agtgggtccc cagttcttcc gcggactgaa aaaggacgga
     2041 ttgccccaag tgggctttgc cgtactgatg tgtatatccg tactgttagt gacctggctg
     2101 ctggccctga tgatgggcta caatgccggt gaagctgccg gactgctggc cggttcgcaa
     2161 accatctccg ccgtcatcgg agtggcagaa gacaccatgg ccaatatggg actggacgag
     2221 gcccaacgac aaagttacgt caacatcatt cccgtatcct acgccgtcac ctacattttc
     2281 ggtactgcag gctcggcatg ggtcctatca tccatcggtc ccaagatgct gggcgggctg
     2341 gaaaaggtga aagccgcctg caaggaactg gaggcgaaga tgggcagctc tctggctgac
     2401 gaaccgggat tcatgccggc ggcacgcccc gtcactttcc gtgcctaccg ggtcgaaaac
     2461 gaatggttca agaatggaaa gcgggtgatt gacctggaag tctacttccg gcagcacgac
     2521 aaacgtctat ttgtggaacg cctccgcaaa tccggagttg tggtggaagt cagcatgaac
     2581 atacagatag agccgggaga cgaagtagtg ctaagcggac gccgcgaata catcataggc
     2641 gaagaaagct ggatagggcc ggaagtacaa gatgcccagc tcctggattt tcctgccgaa
     2701 aagttaccgg ttacaatcac acgcaagacg gttgccggca agacggttgc agttatccga
     2761 agggaaaagt tcatgcacgg tgtcagtatc cggagcatca agcgcgccgg aatatccatt
     2821 cccgtgctgg cacaaacggt agtagatgcc ggcgacgtca tcgaagtggt aggtaccagg
     2881 caggaagtgg aagcagcagc caaacgtctg gggtatatag accgccctac caaccagacg
     2941 gatatgatat tcgtaggcct tggtatcctt gtcggaggtt tgttcggagc actttccgtc
     3001 catatcggcg gcatccccat cagcttgagc acaagcggcg gcgcattgat tgcgggcttg
     3061 ttcttcggct ggctccgcag taagcacccc accttcgggc gcattcccga accttcgcaa
     3121 tgggtattga acaatgtcgg tctgaacatg ttcatcgcgg tagtgggcat ttcggcaggt
     3181 cccagtttcg tgcagggctt ccacgacgta ggtatcagcc tgtttctggt gggagcagcc
     3241 gccaccgccc tgccgctgat tatcggcttg ctgctggcaa ggtatgtttt caagttccat
     3301 ccggcactgg ctttgggtgt ctgcgcgggg gcacgtacca ctacggccgc tttaggcgcg
     3361 gtgcaggatg ccgttgagag tgagacacct gctctgggat acaccgtgac ctatgccgtg
     3421 ggcaatacct tattaataat atggggggta gtcatcgttt tgctaatata agacgatttt
     3481 atgtcaatgc ttactaatcc ggagcattca aagaattatt gccggaaatg caagcgacta
     3541 tatgcccact cactaatgac tattcgtccg acagctgtcg gacgataatt caacagttgt
     3601 cggacgatga ttcaacaact gtcggacgaa aaggaaacat atatcggacg attaatttca
     3661 agcaaggaaa gaaatagtat gccacatgaa cagagattat tcaccgaatg actgaaaaca
     3721 ataaataacg aacctaaact tgagcttatg gatacaaaac ttttagaaaa gaaaatggaa
     3781 tctatcagtc ctttcgaact gaagaaccgc ctgatagaca tggcagacga aagtctgaag
     3841 aaaaccgccc gtaccatgct gaacgcagga cgcggcaacc ccaactggat tgcaaccgct
     3901 ccacgcgaag ccttcttcct gttgggaagc ttcggcctgg aagagtgccg tcgcatcatg
     3961 gatttacccg agggaattgc aggcattccc gaaaaaaaag gcattgcctc tcgcttcgaa
     4021 gccttcctga aaaagaacaa taacgtaccg ggcgccaaat tgctggaaca aacctacaac
     4081 tacctgctga tgcagcatgc cgccgacccc gacagccttg tacacgaatg ggccgaaagc
     4141 attgtaggcg accagtatcc cgtgcccgac cgcatccttc attttacgga aatccttgtg
     4201 caagattacc tttcgcaaga gatgtgcgac aaccgtcctc cccggggtgc ctatgacctg
     4261 tttgccaccg aaggtggaac agccgccatg tgctacatct tcgactccct gcaggaaaac
     4321 ttcctgctga acaaagggga cggcatcgtc ctcatggttc ctgcctttac cccctatatt
     4381 gaaatcccac aactcagccg ctaccagttt cgagtgacca aaatacatgc caaccgcatg
     4441 aatagcgaag ggatgcacct ctggcagtac agcgacgaag acatagaccg cttgaaaagc
     4501 cctaaaatca aggccctctt tgtcaccaat cccagtaatc cgcccagcta cacactcagt
     4561 ccggatacaa tggcgcgcat cgtgagcatc gtcagaaatg acaaccctaa tctgatgatt
     4621 attacagacg acgtatacgg tacattcagt ccacacttcc gttcgttcat ggcagaaatt
     4681 ccctacaata cgctttgcgt ctattcattc tccaaatact tcggtgccac cggatggcgc
     4741 aatgcggtca ttgccctgca cgaattcaac ctgttcgaca agctgatagc caaactgccg
     4801 aaagagaaac gggagattct gcaccaccgc tactccaccc tcactctgga acctgaaaaa
     4861 ctgaagttta tcgaccgtat ggttgccgac agccgtcagg tggcactgaa ccataccgcc
     4921 ggactgtcat tgccacaaca gatgcagatg ggccttttcg ccgcctttgc cctgctggac
     4981 aaggaaaaca aatacaagca aaagatgcag gagattatcc accgccgatt gcatgccctt
     5041 tgggagaata ccggtttcac gctgacggaa gacccgttgc gcgtaggtta ttatacagaa
     5101 atcgacatgc tggtttgggc aaagaagttc tatggggacg actttgtaga atatctgaaa
     5161 cgcacctaca gcccgctgaa cgtagtcttc cgccttgcca aagaaacctc tctggtgctg
     5221 ctgaacggcg gtggttttga cggccccgaa tggagcgtgc gcgcctcact cgccaatctg
     5281 gacgagaaag actatgcgac catcggccga ggcattaaaa agatactgga ggagtatgca
     5341 aaagaattct ttaaaaatgg aaaggcgaaa ggtaaaaatt gaaaattgaa aggtgaaagg
     5401 taaaactttc aaatttcaat taaatagtat acggaaacgg gtcaatccat cgttgtaggt
     5461 acgtagggag aacgtgcaac catgacggct caaaacttcc cggataaaca ccaggccaat
     5521 tccctgcccg ttcggcttgg tggaaaagaa gggactgaag agtttagctt cggtctcttt
     5581 acttatcccc ggaccattgt caacgacttc cacagaagcg ggggcagtgg tccttactat
     5641 tatctcacct tgctgtccgt tttctccggc atccccctct atactttcgg cagcattctt
     5701 gatgatattc acaagcacct gctcaaaaag agaagcatcc atacgcacca ttcccacctc
     5761 cgggtcgcat tccagacgta gctctatatt gcggtcattg cacattcctt ccatgaaacg
     5821 cttgcacatg gacaccaact cattcagttg gacgggcacc agggtaggtt cgggtatctt
     5881 taccacatct gcaaaacggg taatgaaacg gctcatcgag aaacaacgct ccgtacagac
     5941 gcgcatcacg tcgcagatgt cctccatatc atcttctgta gaaagtgcct gctccactgt
     6001 atcgagtgtg gaagtgatgc ccgcagtggt attgttcact tcatgagcta tcatgcggat
     6061 taccttttca taggcacgct tctcggcacg catcacttct tctgtcatac gctctatcaa
     6121 gaaaaaagga tgtttgaacc ctctgtcaat aaaagaagaa tgggtgcatt tataaatatt
     6181 cgcgtcattg agacggacca ctgccgtctc gtctttggga atggacgaaa gttcggcagc
     6241 caacggagag tccatctggt ccagccgctt tgccatcgcc tcctccatac ggacaccgag
     6301 catctttacc gccatcggat tcagttgcga cacttcatcg tccattgtca ggataataac
     6361 ccccattgga gatgcctgaa tcagcaaatc caagaagtga ttctgctcgc gcatgcgcaa
     6421 ccgttcattc ttgagctgct ccatcattcg gttaaagata ttcacaatgc ggtctgcttc
     6481 gtactgccct acccggctga gacgactact gaaatcctgc tcgcgcagca actccatacc
     6541 gctgcctatg gtgttcatcg gcttcactat cttattatag aatactatca gatagataag
     6601 gataaacccg atgagcccct ccaatacgta cagatacaaa agcggcttcc cactcagcaa
     6661 atataccagc attccaccca gaccgagcag aaaaaggaca agtatgaaga aaaagaattt
     6721 tatgcgcacg ggacttgaat attatatttt tctaaacgtc tgtaaagcgc agcgcggctg
     6781 atgcctaatg acactgccac ctgactgaga ttccctttat gctgttccaa cgcctgcaag
     6841 atagtctgcc gctctatttc atccaaggtc atacctgcaa aagaagtacc ttcggcagct
     6901 ttggccggtt cgtcgtgacg cagatattgg gcatcgaaat ccgcggcatc cagcaccggc
     6961 ttgccgctga ccagaatggt acgctccacc agattcttca actcacgaat gttgcccgga
     7021 taaggcaggc gggaaaggaa attcagagcg tcggccgaga aatccgtacg cggcaagccg
     7081 ttcacctctg cctgacggtc ggcaaagtga cgtgccagca aaggaatatc ttcacggcgc
     7141 tcccgcaagg agggcagttt tacggtaatc aggttgatac ggtaaaaaag gtcttcacgg
     7201 aaagtacgtt cggacaccat cttgcggagg tctgcattag tggcggacac aacgcgcaca
     7261 tcgactttgc ggggacggct atcgcccagc acttcgaatg tctggtcttg aagcacgcgc
     7321 agcagtttca cctggcagga agggtcgagg tcaccaatct cgtcgaggaa gatagtacct
     7381 ttatttgcca tttcaaaacg ccctatacgg tcggcgctgg catcggtaaa cgcccctttc
     7441 ttatggccga acatctcgct ctcgaacaag ctctgcgaga tgccgccgag attcaccttg
     7501 acaaaaggct gcttcacacg ttggctgttg atatggatgg cttcggcaat cagctccttg
     7561 cccgttccgc tttcgcccgt aatcagcacc gaagcattgg tacgggctat gcgggccact
     7621 gtgttcaaca cttccatcaa ccctttggac ttacctataa tatggctgcg attcaatgcg
     7681 gtagtctgtt cttccggcac ctctttcggg gcggccgtaa gctcaagggc cgtctcgatg
     7741 cgctgcaaaa gagcagcatt gttccaaggc ttggttatga aatcgaatgc gccggcctgc
     7801 ataccctgca cggcaagctg gatacttccc catgccgtca tcaaaataac gggcacatcg
     7861 ggacggaaca cctttacctg cttcaataag gtaagtccct cttctccggt agtggaaaga
     7921 gtgaagttca tatccatcaa aatcaaggcg ggagcttcgg ccctcactat gtccatagct
     7981 tcgcgagggc ccggagccgt tttcacctca tatccggcac gcttcagcat aaagctgagg
     8041 gaagagcgca cagcactatc gtcgtctatt atcagtatca taaaaattgt agtttgtttc
     8101 ccgcaaaaat aagtaaaaaa gcagagttat gaatgataag ttataagtta tttacctata
     8161 atatcgcata tacggtactt ttaccggcaa ataactcata acttatcact tgcaacccgt
     8221 cgacttatcc tcttaccacc tcttcaaaat cagcttccaa ttccgtatcg cgttcaaaat
     8281 cccaaagggt caagctgcgg agctgataga agtaatacca atagtagtac agctctgaaa
     8341 tatgcttttg acgggcttcg tctttagagt tctgtgcatc gttcaggtcc agggtgctga
     8401 ttttacctat cataaaggtc tctacactag tcttgtaacg cttctcagca atgacatccg
     8461 cctcttcggc tatgtccagc tgttgcgcct ggttgttgaa gttagccacc agcaaaaaga
     8521 tgtcctgatt aaagtccatc tgttcctgac ggattctgga caagaccact tcacggttgc
     8581 tctttgccac ccttaccttg ccgcggcgct tgccccagtc aaggatagga atcttgacgc
     8641 ctacctgcac aatctgattg tcaagcaagt cccggtaggc tgaagagaat tcatggttct
     8701 gccccgtata gcccacactg gcaaagaggt cgatgctgcg caagtttccg cgtgccgttg
     8761 ccacttcata atcagcttcg agctggcggc ggcgaatgtt ctgtgcaaag gagttgcgtt
     8821 ccagtgcctt gttcagcaca cggtcatact ccatctttat atcgggaaca gtggcgggca
     8881 acaccggatt caggctttcc tgctcggaca ccccgaggaa agaacggagc tggaacattt
     8941 ttgcattcag gttgctctct gcctcagtca cgtcggcctt gccctgcaat gaattcagtt
     9001 taagctgcaa caaatcattc tcggatatct gtcccatttt acgtttggct atggccactt
     9061 cataaaggcg gtcggcattc gtcttgttct gcatggcggt agcgagcgat tctttggcca
     9121 gcagcaactc aaagaaataa gtgatggttt tcatcgtcac ctcttccgta gctgaaatga
     9181 actcggcctt tgcctcggca tagcgtacgg gctctatacg gcggttccac ttcaaggtat
     9241 tcactccgaa gaccggttgc gtcaactcca gactcacggg gactgacatg aactgcttcg
     9301 ctcctccgga acccagttgt ttgagataat ccagcgaaga agtcagtgac agcttacccc
     9361 ccgtaaacca aatgttctgg tctaccgaaa gctgtccgga cagccccagt gtattgttgc
     9421 gaacaaagct ataggagccg tcggaattct ggtaggtact gtaggacttg ttatagttgg
     9481 gtagtgtacc ggtgaaattc acttccggca acaagtccgc acggaatgta cggtattccc
     9541 aatacgcggt tttcaattca ttcaatgcca cagcagcatc cacagactgc gtacgggcca
     9601 gtacaatggc ctccgacagc gtaatattgc gttcatgtcc caaagtatca ttctgcgcca
     9661 tggttgccaa cggcatcaaa aaacaaactg caagtaaaat attctttttc atgttcaatc
     9721 tttaaaattg tcgcaaacag aaaagcaaag agtgtgccaa gtggccggaa aggtttcata
     9781 gaggggtaag tgttcatttt cggacagtgg ggatgtccgt tagcggacga tatcaagaaa
     9841 acaaccggtc tctatctaaa gtctgaaaaa atccttctaa agttcaatta accattaatt
     9901 aattgatgaa aaatttcttt attaaggaag aattctcttt ctttgtgctg ctttatacct
     9961 ttattaaaag gatacaatac taacattaat ttatatagtt atgaagattt cacacattga
    10021 gcatctgggc attgccgtta agagcattga agaagccctt ccgtactacg aaaacgtttt
    10081 aggtttgaaa tgctacaaca tcgaaaccgt ggaagatcag aaagttagaa ccgctttcct
    10141 gaaagtgggc gatgtaaaga tcgaattgtt ggaacctact tctcccgaaa gcacaattgc
    10201 caagttcatc gaaaagaaca acggtaacgg tggcatgcat catctcgcat tcgccgttga
    10261 agacggagtg gccggtgcgc ttgccgaagt cgaagaaaaa ggtatccgcc ttatagacaa
    10321 agctccccgc aaaggtgcag aaggtctgaa cattgcattc ctgcatccga agtcaactct
    10381 cggtgtcctg accgagcttt gcgagaaacc ggaataagca agactgtaaa atcatcaaat
    10441 cataaattgt ataaacactt aaagaatata aattcatgag taatcaactt gaaaagatta
    10501 aagagcttat agaccgccgc gctgcagcac gtctcggtgg tggtgaaaaa gcgattgcaa
    10561 agcaacacga gaagggtaaa tatacagctc gtgagcgtat agccatgctt cttgacgaag
    10621 gcagtttcga agaaatggac atgttcgtag aacatagatg caccaacttc ggcatggaaa
    10681 agaaacacta ccccggtgac ggtgtagtaa ccggttgcgg tacaatcgaa ggccgtctgg
    10741 tttatatctt cgcacaggac ttcacagttt ctgccggttc actgtccgaa accatgtctc
    10801 tgaaaatctg taagattatg gaccaagcca tgaaaatggg tgctccgtgt atcggtatca
    10861 acgactcggg cggtgcacgt attcaggaag gtatcaatgc cttggctggc tacgctgaaa
    10921 tcttccaacg taacatcctt gcttccggtg tcatcccgca gatttccggt attttcggtc
    10981 cttgtgccgg tggtgccgtt tactctcctg cattgacaga ctttactttg atgatggaag
    11041 gtacatccta catgttcctt accggtccga aggtagtaaa gactgtaacc ggagaagacg
    11101 taagccagga aaacctgggt ggcgcgagcg ttcactccac caaatctggt gttactcatt
    11161 ttactgcaca gacagaagaa gaaggtttgg cccttatccg caaactgttg agctacattc
    11221 cccagaacaa cctggaagaa gctccttatg tagactgcac agaccctatc gaccgtctgg
    11281 aagattccct gaacgacatc attcctgata acccgaacaa accgtacgat atgtacgagg
    11341 taattggcgc tatcatagat aatggtgagt tcctcgaaat ccaaaaagat tattcaaaga
    11401 atatcattat cggtttcgca cgtttcaacg gacagtccgt aggtatcgtt gccaaccagc
    11461 cgaagtatct ggcaggtgtg ctcgacagca acgcatcccg caagggcgca cgcttcgtcc
    11521 gtttctgcga cgccttcaat attcctatcg tatcattggt agacgtaccg ggattccttc
    11581 cgggaaccgg ccaggagtac aacggcgtca tcctgcacgg tgccaaactg ctgtatgcat
    11641 acggtgaagc tactgtaccc aaggttacca ttacactgcg taagtcctac ggtggttcgc
    11701 acatcgtgat gagctgtaag cagctgcgtg gcgacatgaa ttatgcttgg cctactgctg
    11761 aaatcgctgt aatgggtggt gcaggtgctg tagaagtatt atatgcccgc gaagccaaag
    11821 agcaggaaaa tccggctcaa ttcctggctg aaaaagaggc tgaatacacc aagttgtttg
    11881 ccaatcctta taatgcagct aaatatggct acattgatga tgttatcgaa ccgcgtaaca
    11941 cacgtttccg catcattcgt gccctgcaac agttgcaaac caagaaattg actaacccgg
    12001 ctaagaagca tggtaatatt cccttgtaat caagcttttc acactaaaac aagaacgatt
    12061 atgaataaaa caaaaatcgg aatattcctt tcattgatgc tggtgttggg cttttgctct
    12121 tcttgcaaag aacagaaatc gaacaacaaa ctgctgctga atgaagtgct ggtcaacaac
    12181 gagagcaact atcaggatga ctacggtgtg cacagcgcat ggattgaaat attcaacaga
    12241 tcatacggca gcgccgacct tgcaggttgc tatctgaaat tcagcagcca gccgggtgat
    12301 actgccagtt atttcattcc caaaggtgac gttctgacac tcataaaacc acgtcagcat
    12361 gcacttttct gggctgatgg agaaccaaga cgcggtacat ttcatacgaa cttcaaactg
    12421 gatgccacaa atgccaactg gattgggttg tatgattccg gcaagaaatt gcttgatcaa
    12481 gtcatagtgc ctgccggtac tttaaaagcc aaccaatcct atgcccgtgt cagtgatgca
    12541 gccgaccaat gggaagtaaa gggtggaagc gaagataaat atgtcactcc gagtaccaac
    12601 aacaagacta tcgacagcaa tgccaaaatg gaaaaattcg aagagcatga cagcgtaggt
    12661 atcggtatgg ctatttctgc catgagcgtt gtattctgcg ggctgatatt actctacatc
    12721 tccttcaaga ttataggtaa aatatcagtt aacctcagca aacgcaatgc catgaaagct
    12781 aaaggtatta ctgataaaca agaagcaaaa gagaaacaac tggggcaggc tccgggagaa
    12841 gtttttgctg ccatttcaat ggccatgcac gaattccaaa gcgatgtaca cgatgtggaa
    12901 gacacgatac ttaccattac ccgtgtaaaa cgcagttact caccgtggag ttcaaagatt
    12961 tatacgttgc gtgagactcc tcacaaaaag taagtcaccc ataataaaat aaaacgatga
    13021 aagaatataa atataaaatt aacggtaacg tatataaagt tgccattgga gatattgaag
    13081 acaacatcgc tcatgtagaa gtgaacggta ctccctacaa agttgaaatg gaaaaagcac
    13141 cgaaggtagt tgttaaaccg gtagcacgtc cggcagccac atccgctcct gctgctcctg
    13201 ctactccggt agtaaaaccg gccgctgctt ctaccggcaa gtcaggtgta aaatctccgc
    13261 ttcccggtgt aatcctcgat atcaaagtaa atgtcggcga tacagtaaag aagggacaag
    13321 ttatcatcat tttggaagcc atgaagatgg aaaacaatat caatgctgat aaagacggta
    13381 agattacagc catcaatgta aacaaagggg actctgttct cgaaggtact gacctcgtaa
    13441 ttattgaata atatgggaga atttatcaca tttttaggaa acaaccttgc cgacttctgg
    13501 acttatacag gttttgccaa tgcaacggta ggacatgtgg taatgcttct ggtaggtttg
    13561 tttttcatat acttggctgt agccaaggaa tttgagccga tgctattaat tcctatcggt
    13621 ttcggtatgc tgattggtaa tatacctttc aatatggagg ctggattgaa agtcggtatc
    13681 tatgaagaag gttccgtact taatattctg taccagggag taacctccgg ttggtacccg
    13741 ccactcatat tcctgggtat cggtgccatg acggatttct ccgctttgat atcgaacccc
    13801 aaattaatgt tggttggtgc agcagcccaa ttcggtatat tcggtgctta tatgattgcc
    13861 cttgccatag gatttgaccc gatgcaggct ggtgcaatcg gtatcattgg tggtgccgat
    13921 ggtccgactg ccatcttcct ctcttccaaa ctggctccta acttaatggg tgccattgcg
    13981 gtatcagcct attcatatat ggcattagta ccggtgatac agccgcctat tatgcgttgg
    14041 ctgaccagta aaaatgaacg tcttatccgt atgaaacctc cccgtgtggt ttcacatacg
    14101 gaaaaagtaa tgttcccgat tatcggtttg ttactgacca cattccttgt accatccggt
    14161 ctgcctttgc tgggtatgct gttcttcggt aatttactga aagaaagtgg agttacacgt
    14221 cgtctggcaa acacagccag tggtccgctg attgatacca ttactattct gcttggtttg
    14281 acagtaggtg cttctacgca agcatccgag ttcttaaccc ttgattcaat caagatattc
    14341 ggtctgggcg ccttatcatt tgtcattgcc acagcatccg gcgtcatctt cgtgaagatt
    14401 ttcaacctct tcctgaagaa gggcaacaag attaatccgt tgatcggtaa tgccggtgta
    14461 tctgccgtac ccgactctgc acgtatctcc caagtagtag gtctggaata cgatcctacc
    14521 aactatctgc tgatgcatgc catgggcccg aacgttgccg gtgtaatcgg ttccgctgta
    14581 gcagcaggta tcctgctggg attcttaatg taatacattt attcattccg ttatccggat
    14641 tgaattccga actattttaa agcccctcca tcatttttgg aggggctttt tcgttaatct
    14701 atctaaaaca gattacgatt atttcgtaaa tacattcttt ttagtaactt gcagtcagtt
    14761 taacctcata taaatgatat actgtatgcg aaagcttttt atctccttat gtttcagtgc
    14821 atgctgttca cttctggcgg cacagaccac aaaccccatt caagaggcga tggccaacta
    14881 cgattatgaa acagccttga tgctgatcga tcaagaaacc ccgaccgtcc ccctactcta
    14941 ccaaaaaggg aaagcgctga aagggctggg caataacctt gaagctctga gcgtatttca
    15001 ggaagtcgta gctcaggatt ctctcaatcc ccgggcatac attgaagctg ccgaatgctg
    15061 caaatcactt gccaaatata gcgaggcact ggattactac cagaatgcgc tccacataaa
    15121 tccggacaat aaatacgcac gcattcagta tatcagtctg ctgatgaaca tgaagagata
    15181 ccgtgagtct ctaaaggaaa gtaacctgct ggcagaaagg gacagttccg cctatgtact
    15241 acaccttaga gccgaaagta tggggcaagt ctatgacaac acagaaatca tgcatgtgat
    15301 agatgcctac ctggacatac agaaaaggta tcccaatgat tacctgtctg ctgccaaact
    15361 cggcaacatc tatgtagcag gccaccagta tgaagacgcc ataagcataa cggagaaata
    15421 ccgttccata gactccacca acgtccttgt gaaccgcatc aatgcccaag cctattgcct
    15481 gaacaaagat taccccaaag caatagaaag atatgaacaa ctgttacagg aaaaagacag
    15541 ttctttccaa acctgcttct acgccggaat cagctattat gccctcgaag acttctaccc
    15601 agcacacgac ctgctggaaa gggctcttaa agatgacaat accaacatca acgttctcta
    15661 ttatctggga cgcgcctgct ccaagacatc atggaaagag gatggagtga cttatctgga
    15721 aactgccgta agcctcgcca tgcccagcga cagtgtcatg tcccgcctat atgtggggct
    15781 tgcggactgc tacaagatgg catttcaata caccgaccag gcgaataccc ttctgacgca
    15841 atacgaaaaa tacgaccggc agaaacacaa actgctctac gacgcagcct ttatctatta
    15901 ttactatctg aaagatgtgt ccaaagcaga gagatatctg acggcatacc tgaaaacccg
    15961 tccgaaaaac agcaaggaca aagtgcagga agtagatgcg gacggagttc ccatcatcgg
    16021 agaagacaac cgatacaatg ccgccgaaaa ctggctgaag gacatcagag aaaagcgcaa
    16081 gaaagaggac ttcttcaagg gaaaggtcga taccgccagc gtaaccccca tcaaatagcc
    16141 ccaatgaaaa cgtttgcata atataataag gtacagtaac ggagaaagat taactttctc
    16201 cgttatttgt tttaaattag cgcaaaaatt aaccgtaaag ttactatcat gaaaaaagta
    16261 ttcttaatct tgggaacact cttactctcc ctcagtacgt atgcagctat gaatgtgaac
    16321 aaaatcgacc ctccgttttg gtacaccggc atgcagaacc cggaactcca gctgatggtc
    16381 tatggcgaag gcatcggcaa cgcggcagta tccgtcaatt atcccggcgt ctcattgagc
    16441 agcaccgtca agctggaaag caacaactac ctcctggtct atctgaaact ggacaaggat
    16501 gtaaaacccg gcaaattcaa cctcaccttc actgaaggaa aaaagaaact cgtaaaggaa
    16561 tatgaactga aggcacgcaa caagaaaggt tgcgaacata aaggtttcga cgcctccgac
    16621 gcactgtacc tgctgatgcc cgaccgcttt gccaatggca acccggacaa tgaccagatt
    16681 gcgggcatgg ccgagtacaa gatagaccgc aaagacccca atgcacgcca cggcggtgac
    16741 cttgccggca tcgaacaaca cctggactac ttctccgacc tcggcgtcac agccctctgg
    16801 tttactccgg tactggaaaa caacatgacc ggcggttcct atcacggcta tgccaccaca
    16861 gactactaca aggtagaccc gcgcttcggt accaacgaag aatacaagca actgattgaa
    16921 aaagcccatg cacgcggcat caaaatcgta atggacatga ttttcaacca ctgcggcgta
    16981 gagcatgtat ggattaagga catgccctcc aaagattggt tcaacaaccc cgaccacgaa
    17041 aacaacttcg tgcagacctc cttcaaactg accccgcacg tagaccctta tacttcccag
    17101 tacgatgccg accagatgaa cgacggctgg ttcgtacctt ccatgcccga cctcaaccag
    17161 aagaaccctc acgtttaccg ctacctggta cagaacagtt tctggtggat tgaattcgcc
    17221 aacatcgacg gcatccgcat ggacacttac ccgtatgccg actatgatgc catgagcaac
    17281 tggatgaaag agctaaacga agaatatccc aactacaaca ccgtgggcga gacctgggtt
    17341 accgaacccg cctacaccgc ctggtggcag aaggattcca agctatcagc ccccaagaac
    17401 agtaacctca agaccgtcat ggacttcagc ttctttgaca agataaacac cgccaagaat
    17461 gaacagaccg agacttggtt caagggactg gaccgcatat acaataactt cgtatacgac
    17521 ttcctctacc ccaaccccgc ttccgtactg gcattcatcg aaaaccacga caccgaccgc
    17581 ttcctgggcg aaggcgacaa ccttccgatg ctgaagcaag cctctaccct gctgcttacc
    17641 acccgccgca ttccgcaact ctactacgga acggaagtca tgatgaatgg cgtgaagagc
    17701 aagagcgacg gctatgtccg caaggacttc cccggcggat ggaccggtga cgcaacaaac
    17761 gcactgaccc cagccggacg taccaagata cagaacgagt gctacgactt ctacaagacc
    17821 atcctaaact ggcgtaaagg aaacgatgtg attgccaaag gcaacatggt gcagttcatg
    17881 gtacagaatg gtgtttatgc ctacgcacgc cagtacgaag gcaagacgat attcgtgatg
    17941 ctgaacggta cagatgcaga gaccaccgtt cctttgaaat tctacaagga aatcctgaaa
    18001 aacagcaagc agggaaaaga tattcttagc ggcaaggcca tcaccttcgg tgaagagctg
    18061 aagatgggcc ccagagaatc attagtgata gaattataac gcgtactcca cacagagagc
    18121 tcattcttgc aaatctccct tgcagatagc tggcagacac ttctcctgcc agccatctgc
    18181 aagggatttt tagtatggaa taggtgtcac ggggatatgc ttttcaccgg tctcaaatat
    18241 agctaatctg ttagttcata acggtgaaca ctttgttcca gtatagagaa acaaagtgtt
    18301 cagatatgta gaaacaaagt gttcttacgt attggaacga agtgtttttg catattggaa
    18361 caaagtgttc tctttattga aacaaactgt tcagttaagg gaaacagact gttttgttaa
    18421 aggaaacaga ctgttgtaca cgttgaaaca tccgcttctg aaataagcgg cgaacttaac
    18481 catcccacaa caccggccta tatacaacaa gtcagccctt gcaacatcaa tattgcaagg
    18541 gctgacgcta tattcggatt atctttcgat tagtccagtt gagccaattt gttctctgaa
    18601 ccaagcacgt tgatgatttt atgcttgtac agtttttcca tattatcacg agccgggccc
    18661 agatacttac gcgggtcgaa ttctgccggt ttttcagcaa atgtcttgcg gatagcagct
    18721 gtcatagcca gacgtgagtc agagtcgatg ttgattttgc aaacagcaga cttggcagcc
    18781 ttacgcaact gctcttcggg gataccgata gcagcttcca gcttaccacc atacttgttg
    18841 atagtatcaa cttcttcctg aggaactgaa gaagaaccgt gaagaacgat ggggaatccc
    18901 ggaagtttct ccattacagc atccagaacg gcaaattcca aaggaggagg aaccagacga
    18961 ccggtagcag ggtcaacgtg gcattgttcg ggtttgaact tgtatgcacc atgagaagta
    19021 ccgattgaga tagccagtga atcgcaacct gtacgggtag cgaagtcaat aacttcttca
    19081 ggattagtat atgtatggtg ttctgcagaa acttcatctt ctacaccggc caatacaccg
    19141 agttcgcctt ctacagttac gtcgaactga tgggcatagt caactacctt cttagtcagt
    19201 gcaacgtttt cttcgtacgg aaggtgtgaa ccgtcaatca ttactgaaga gaaaccggag
    19261 tcgatacagc tcttgcaagt ttcgaatgta tctccgtggt caaggtgaag aacaatttca
    19321 ggatgtttgc aacccaattc cttagcgtac tcaacagcac cctgagccat gtaacgcaac
    19381 agcgtagcgt tggcatactg acgggcaccc ttagatacct gaagaataac cggagacttt
    19441 gtttcaactg cagccttgat gatagcctgc atctgttcca tattgttgaa gttgaatgcc
    19501 ggaatagcat atccaccttt gatagcctta gcaaacatct ctcttgtgtt taccagtcct
    19561 aaatctttgt aattaaccat tttgtttaaa ttttattgtt agtgaattaa aattctacgc
    19621 aaaagtaatc attatccttt aaagtaaaga acttgagagg aataaaatat ccggctcatc
    19681 ctaccaaatc cattctattt taaagctatt ggcttcattt aacagattat tgtaatctct
    19741 atattacaaa ctctttgcat ttatctctgc cagccatact tttgccatct atacttctat
    19801 caacaaaaaa gccggagaac atgtttgctc tccggcatct gtttacacat tattatgtaa
    19861 tactaatttt tcagatagat gatggtcggc aaatggtcac tgtaaccgtt cagccaagtc
    19921 ctgcctccat gcgtacgcaa gggggaacct ttgtatttgc catcctgctg aatcagataa
    19981 tcgcggatga aaacttcatt gtgatcatag cgcaaccctt tcttagcctt cagcaacggt
    20041 ttcgaaatga caatctggtc aaacaagttc cacttgcccc gatagagcaa tgtccccact
    20101 cccttgtctt ccagtgtctc ccaccaggga ttgtagaatt cgcctttctt cacctgcttc
    20161 ggatatttgc gtgcacccag cacctccatg ctttcatcca tcgggtcgtc attcatatcc
    20221 cccatcacga tgagcttcag cttcttgtcg ctacgcatca gagagtcctt caaggccttt
    20281 acttgcctgg ctgcatgcac acgcaccggt gacttcgccc cacgggaggg ccagtggttc
    20341 actatcacgc agacacgctc tcccgccagt tgtccgtcca caatcaggaa gccgcgcgtc
    20401 aagtgcaccg tatccccctc aaaaggagtg gaaagcacca acttcgagtg ggtaacgctg
    20461 aactgcttcg ggtcgtacag caaggcacag tctatacccc gtctgtccgg tccttcataa
    20521 tgcacgaact cataattgga aatggccggc tgcttcacga ggtcttccag cacccggctg
    20581 ttctccgcct ctgccacacc gatgaatgcc ggaccttccg gcactaaatc acgcgaaagg
    20641 gaacccaaca ctttggaaag gttctgcagc ttggactcat acttctttac cgtccattgg
    20701 taactgccgt cgggcaggaa ctcatggtcg ttcttaccgg catcatgaac cgtatcgaac
    20761 aggttttcaa gattatagaa cgcaacacta tacagtttcc gttccgcatt ttgtgccccc
    20821 agcgttgcca cgcacagcca gaaagagcat aagacaagta gtttcctcat aaattcacaa
    20881 gattaagtcc tgcaaaaatc agaaataaaa tgcgataaac ctactaaata aaaataaatc
    20941 tgaatttatt ttgtagagtc tccaacttgc actatctttg cgctctgaaa agaagaccat
    21001 tacactattt attaccaaaa tagtaacaga atataaattt ttaaaagaaa atatcaaaat
    21061 gaaaaaaggt attcatcccg aaaattaccg tccggtagta tttaaagata tgtcaaatgg
    21121 tgatgtattc ttgtctcgtt ccacttgcaa cacgaaagag actatcgaat tcgaaggtga
    21181 aacttatccg ctggtaaagc tggaaatctc cagcacttct cacccgttct acacaggtaa
    21241 gtctaagctg gttgacactg ccggtcgtgt tgataagttc atgagccgtt acggtaaccg
    21301 taagaaataa tcagttttca agcaaactga aaaaagggag tctttcactg aaaggttccc
    21361 ttttttgttt ccgcctccca ctgcaggacc gataaatagg gaatctccta tcacagaata
    21421 gggaaaaaaa cgagaaagga gaaaaacact tccctatttt tgtatcatca aaaccgaaaa
    21481 catatactaa tcatgaaacg actcgccacc ctattcatcc tgacaatcct tgtcgcaacg
    21541 gcaggatttg ccaagcccaa aaagtacaaa gatttaagcg gaaacatcgc tgtcaaagga
    21601 gaattgacaa aagagtaccg gcaatctccc gccggtacac cggtcattat ccgccgggtt
    21661 gtcaaaatga agaatcccgg tgaaagcagc aacaacattt gctatgctgt cgaaatgaac
    21721 ggcatacaag agaccattcc tttgaatgag atggggcaca ttgccatatc cgctccgcaa
    21781 accgaccggg aattctggca gcagatatac ttgaaaaacc atctttacga atatttcagc
    21841 gaccgcggct acaagcacaa actgcgccag gaaatcgacg aagagtgcct ggagtatctc
    21901 gacaaactga atgagatagc ctatcaggaa gattacatcg tttcgtacgt gcagggagtg
    21961 ttctccaagt tgaacgccac caccattgac agcaatcgcg gggagagtct gaacatacgt
    22021 atcatccagt cgcccgaacc agatgccttc atgcttccca acggctccat ggttatcagt
    22081 acgggcctcc tctgcactct tgattccgaa gacgaactgg ccgccgtcat cgcatgtgag
    22141 ctgggacatt tcgtcctcga ccatcaggta aacaacattt accgtgccga gcggcgtgcc
    22201 aagcgtgcag ctttttgggc agatgtcttt gccactaccg ccagtgcagc cctcgatgtg
    22261 gcctactggg acgataatga agatgcttat gccgtcagtc tggtggcaga tatcggagcc
    22321 atcgcttccc ttttgagcat tccggcaacg gaccggttgg ggatgaaata caaaacttcc
    22381 caggaaatct cttcagaccg ccttgcgcgc caacttctgg cattcaaggg atataatccc
    22441 gacggaatcg catcggccct cggtaaaatt atagggtatt acaacctgca ccaacgcaac
    22501 aaggacattc ctcgctacgg cagcatcggc aacctgcaaa agcgtataga aaaggccggt
    22561 gaatcccata gcctgagtgc ccgcccctac ctacggacca ccagcgatgt cgtttctttc
    22621 aacgcaagta tgaactacgc caacaagcgc tataaggaaa ctgcccggct gatacgcaag
    22681 aacattgaca acagactagc cacagacaat gactacatca tcctggtaaa agcggaaatg
    22741 gcactgtcta atacggaaga agtgaacaac cgctgcctcg ccatgcttga taaagcccag
    22801 gagatggcag gaacaagccc caatctggac atatataaac aaaaaatact attattgatg
    22861 cgcatgaaca aacaagccca agccgccgat atactgaaag aatatatcac cttgctttcg
    22921 gcctacgaag gccagggcat agaaggaacc gaaaaggaat ggaccaataa agagataggt
    22981 tgggcaaacc aaatgctgga caggataagc agaatataga gaaaggaata actaagaatg
    23041 aagaatttga ctgcgcgatg atgccgcatg acaaattctt cattcttctt attttagtta
    23101 ttcattcaaa ttactgtttg cggaacggcg gtttcacaac cacagctttc agcttacgtc
    23161 cccgcatgtc aatgcagatt tccgtaccga ctttgctgta ctcgggtctg atatacccca
    23221 ttccgatacc aatcttgcgg gtaggcgaca tagttccgga ggtaaccaca ccgatggcag
    23281 taccgtctgt actatacagc tcgtaaccat gacgggggat accgcggtct atcatttcaa
    23341 atcccaccaa cttacgggta gtgccttccg ctttctgttt ttccagcatc gggcgattgg
    23401 tgaagttctt tccctccaca aacttggtaa tccatcctaa acccgcttca atgggcgaag
    23461 tggtgtcatc caaatcattg ccatacaaac agaagcccat ttccagacga agcgtatcgc
    23521 gcgcacccag accaaccggc ttaatgccga actccgcgcc tgcctcgaac acggcatccc
    23581 aaatcttcat ggcagcctcc ggatagaagt aaagctcaaa accacccgca ccggtatatc
    23641 cggtattgga gataatgaca tccttttctc cggcaaactc accgtgggta aaagtatagt
    23701 aaggaaggtc ggaaagattg atggaagtca gtttctgcaa cgtctgaata gccttcggtc
    23761 cttgcacagc aagctgtgcc atgtggtcgg aagcattttc caattcagcg ccttccgtgt
    23821 tatgagacac acaccagttc cagtctttct caatgttcga cgcattcacg acaagcaggt
    23881 atttctccgg ctcataatga tagaccagaa ggtcgtctac aatgcctccg ttgtcattgg
    23941 ggaagcaggt atactgtact ttcccaggtg tgagggcagc tacgttattg gaagtcactt
    24001 tctgcagaaa gtccaaagca tggggacctt tcacccagaa ttctcccatg tgtgagacgt
    24061 cgaatacacc gacaccctga catactgtaa gatgttcgtc aatgatgccg gaatactcga
    24121 taggcatatt atatcccgca aactcgtgca tcttggcacc cagcgagatg tgtttttcgg
    24181 taaacggagt ggttttcatg gaactattag agttatgagt tatgaattat ctatttgctt
    24241 gctacgagct cggcaatctt gacgatgacg ttcatggctt tctccatgtt ctggataggc
    24301 acgaactcat agcggccgtg gaagttcaag ccaccggcaa agatattggg acaaggcagg
    24361 cccttgaaag agagctgggc accgtccgta cctccgcgaa tggcttttac acgaggctct
    24421 acacctaccg ccttcatggc ggcaaaagcg gtgtcgatga tatgcatcac cggttcaatc
    24481 tgctcgcgca tattatagta ttggtcgcga agttccagag tagcggtacc cggaccgtat
    24541 tcttcattga tttttgccac aagacgttcc atctccttct tgcgctcttc gaagcgggtg
    24601 cggtcgtggt cac
//
