LOCUS       gnlProkkaNKJFOKIJ_65   10835 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKJFOKIJ_65.
ACCESSION   gnlProkkaNKJFOKIJ_65
VERSION     gnlProkkaNKJFOKIJ_65
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 01:27:47
            Original ID  :: gnl|Prokka|NKJFOKIJ_65
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10835
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10835
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1936:6250]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1937..6250
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10835
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10835
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(48..389)
                     /locus_tag="ctg65_1"
                     /transl_table=11
                     /translation="MKLTTYVLNLLKDKERKEYMQYVLSDYPNLDIQYVNAINGKNLSL
                     DEILNQFDNNKAYKRYGRECDLGEIGCSLSHRLAFDLLMNSESNYALILEDDIVIGDGF
                     SSVLENYCH"
     CDS             complement(494..859)
                     /locus_tag="ctg65_2"
                     /transl_table=11
                     /translation="MLGFRRTAKLTDKIAKIDKGKTNKRVGVFVESIGEHNIFATEYFA
                     SKTNKRVGVFVESIGEHNIFATEYFASTIQLKFEGIYFNAPKEYRKCLTQLYGDYMQLP
                     PENRRISGHSFKACYRL"
     CDS             complement(904..1395)
                     /locus_tag="ctg65_3"
                     /transl_table=11
                     /translation="MKDKTCHIITDDNIKEIELSILKYIDLQCKKYNLRYYLGYGTLLG
                     AVRHQGFIPWDDDIDIWMPREDYDKFISLENSLENSKFKILSPLNNSDYYYGFAKLVSR
                     NTELQEIGFLPIKDYGVYVDIFPLDNIATEHPFLHFIAKYIIMARIASCNIKPLVKSDA
                     "
     CDS             complement(1464..1940)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 70.3;
                     E-value: 2.9e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_4"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYSNIY
                     LGKNAEIRSGCYLIARDKIIIGENSTLAYGTTILTTADPNGPYNALAILYPYKKAPVVI
                     GDNVWIGANVTILPGITIGDYVVVAAGSVVTKDVPSGVLVAGVPAVVKKQLLME"
     CDS             complement(1937..3058)
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg65_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_5"
                     /sec_met_domain="Aminotran_5 (E-value: 1.7e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        complement(1961..2968)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg65_5_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg65_5_Aminotran_5.1"
                     /locus_tag="ctg65_5"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             complement(3068..4192)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_6"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.2e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             complement(4209..5510)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_7"
                     /sec_met_domain="CTP_transf_like (E-value: 2.1e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9e-122, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.1e-63, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(5531..6250)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.3e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_8"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.4e-17, bitscore:
                     52.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(6314..7249)
                     /locus_tag="ctg65_9"
                     /transl_table=11
                     /translation="MGNAKGSNGLAGLAASFLGDGALIGESTDALNASLSADIVSSTPF
                     LLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVKSLFGEDTVPASG
                     GRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITAVIADSVVHKLQE
                     YIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVLQSVRAEQERLQN
                     DMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGLKIYILLFVFLSV
                     SGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(7219..7461)
                     /locus_tag="ctg65_10"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLLLKWVMRREVMV"
     CDS             complement(7472..7654)
                     /locus_tag="ctg65_11"
                     /transl_table=11
                     /translation="MNGQVTKVKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFS
                     SLGMMIASIANLIKK"
     CDS             complement(7651..9882)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 21.3;
                     E-value: 1.6e-06)"
                     /gene_kind="transport"
                     /locus_tag="ctg65_12"
                     /sec_met_domain="Poly_export (E-value: 2.6e-18, bitscore:
                     55.8, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCSMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSQSTGTDINESRLREETKENTSDMLED
                     HPTTEDLAREDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKGALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDMDYSIYTMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAQPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQPVAVLIMQGRVRSSLFT"
     CDS             complement(9898..10266)
                     /locus_tag="ctg65_13"
                     /transl_table=11
                     /translation="MDAVILQENIEGLLNLVRMLLPGGGSAGCVYLDDLSALQRSIHKQ
                     INDLYSQRGKTPEQDATLCLAILQGYNVSMYANPEDEDRKRSVLQRSLTLLDVLPPSLL
                     KQQLSAVCHGMQELCETN"
     CDS             complement(10277..10834)
                     /locus_tag="ctg65_14"
                     /transl_table=11
                     /translation="MLNAGPINGTGEGVAHSKRWYVALVRMHHEKKVSEHLDKMGIENF
                     VPVQQEFHQWSDRRKLVTSVLLPMMVFVHVDPRERMEVLSFSTVSRYMVMRGESSPAVI
                     PDEQMARFRFMLDYSEESISMNSAPLARGEKVRVIKGPLTGLVGELVHVDGKSKIAVRL
                     NMLGCACVDMPVGYVEPIMAAV"
ORIGIN
        1 agagacacca cctgacaata aaataacaca aggagcatcg atatcaatca atggcaataa
       61 ttttccaata cgctactaaa tccatcccca ataacaatat catcttctaa aattaaagca
      121 tagttactct ccgaattcat taataaatca aacgccaatc gatgactcaa actgcaccca
      181 atttctccta aatcacattc tcttccatag cgtttgtatg ctttattatt atcaaattga
      241 ttcaatatct catccagact aagatttttt ccatttattg cattaacata ttgaatatct
      301 agattaggat aatcgctcaa tacatattgc atatattctt ttcgttcttt atctttcaat
      361 aaattaagaa catatgttgt tagtttcata atctgtaaca tgctttaaat gaatgaccag
      421 aaatgcgtct attttcgggt atattctttt cgttctttat ctttcaataa attaagaaca
      481 tatgttgtta gtttcataat ctgtaacatg ctttaaatga atgaccagaa atgcgtctat
      541 tttcgggagg tagttgcata taatctccat aaagctgagt caaacatttt cgatattcct
      601 ttggagcatt aaaatatatt ccctcaaatt tcaactgtat tgtagaagca aaatattctg
      661 ttgcaaatat attatgctct cctatgcttt caacaaagac ccccaccctt ttattcgttt
      721 tagaagcaaa atattctgtt gcaaatatat tatgctctcc tatgctttca acaaagaccc
      781 ccaccctttt attcgtttta cccttatcta ttttagctat cttatccgtt aattttgctg
      841 ttcttcgaaa tcctaacaat gtcccaatta ttcctataaa gcgaaataaa atagcttttt
      901 ttcttatgcg tcagatttaa ccaaaggttt tatattacaa gacgcaatcc ttgccattat
      961 tatatattta gctatgaaat gtaaaaacgg atgctccgtt gcaatattat ccaaaggaaa
     1021 aatatccaca tatacaccat aatccttaat aggaagaaat cctatttcct gaagttctgt
     1081 atttcttgat actagtttag caaatccata ataataatct gaattgttca aaggagataa
     1141 aatcttaaac tttgagtttt ccaatgaatt ttctaaactt ataaatttgt cataatcctc
     1201 ccgtggcatc cagatatcaa tgtcgtcatc ccaaggaatg aaaccttgat gacgcactgc
     1261 tcccaataaa gtaccatatc ccaaataata ccttagattg tactttttac attgtaaatc
     1321 aatatatttc aatatagata attctatttc ttttatatta tcatctgtta ttatatgaca
     1381 agttttatct ttcattattg aggcattaaa ttatacttct tatgtaatga tattgtctga
     1441 caataagaat aaaacaatta ttcttattcc atcaaaagct gttttttcac aacagctggt
     1501 acaccagcaa ccaatacccc tgaaggtaca tcttttgtta caacagatcc agctgctact
     1561 acaacgtaat caccaatagt tattccagga aggatggtaa cattagcccc aatccaaaca
     1621 ttatctccta taactaccgg tgccttttta taaggataaa gaattgctaa tgcattatac
     1681 ggtccattag gatcagcagt tgtcaatata gtcgttccat aggcgagtgt tgagttttct
     1741 ccaataatga ttttatcacg agcaatcaga taacagcctg aacgtatttc agcattttta
     1801 cccaaataga tattgctata tttgcctact aagcgaaagc tacgaatagg cactccagaa
     1861 ataacacttt ccggatggaa gtgtatacca cgaagggaaa aataaaaatg acgaatcttc
     1921 aataatattt ctgcaatcat gacatcggta atgtgacgtt ataatgattt aatgcagctt
     1981 ttagtacttt aaagaagttc tcaatatcat ctacttctat ctctcctaaa gcacagattc
     2041 taaaagtatc ctcagttgat atcttacctg gataaatcgt aaatccacgc tcataacaat
     2101 aatcatgtat tttctcaaaa tcccagttgg gatcttctgg gtattgaact gagacaacca
     2161 gtcctgactg ccattcacgc tttattacac ttttaagacc aatttcattt atacctgaat
     2221 gaatagcctc aaaaactctt ttgtgacggg caaacttagc ttcttcgccc acttcaaaat
     2281 attcatttaa tgcctgacga gtggcgtaaa tagtttgtac cggtggagta aaatgcattt
     2341 cacctgttct ctcaaaattc tcatactgca aataaagatt acaatagtaa gaacgcttgg
     2401 gatatttttt tgaaaactta atctgttcct cattgcctat aataaaagaa agacctgtca
     2461 tcgcttgaag tcctttttga gcagatgcca tacaaaaatc cacattatct ttctctatat
     2521 caaaaggaat catgcccaaa gaagaagtag tatcgacgac aaatttagcc tgatatttat
     2581 gagctatagc gcccatctcg cgaatagggt tcagaattcc tgtacccgtc tcgtgatgag
     2641 tagtataaac catagctata tcaggatttt cttgcaacac attttccacc accgataaat
     2701 caggacgttc ataaacggaa aattccaaat taatatgagg caaaccataa tattgacaca
     2761 cttctacagc acgggtacta tatgccccat tattcactat aagcaccctt ttgtcttcag
     2821 gaagaagaga atttagacat atatcaatat tgatggttcc tgagccacaa aataatacag
     2881 cggtatgttt ttccaaattc ccatgagcaa ctctgaccaa atcgtcccga agttgtttca
     2941 tcatacctgc gaattctttc tcgcgaggac aaatatccgg aacaacttgt gccattttta
     3001 cactgtcagt agtagtggca ggcccaggat ttaataatat ttttctttct attttcatcg
     3061 aatatattta ttttaaaaaa tccataaaat gctccttatt ctctatagga gtagtcgtgg
     3121 gacgtcccaa attctcccga gaatctattt taacctttat ttccaacaaa acaggaccac
     3181 ataactttgg aagctgcttc attgcttctt caatttcaac ttttgtacaa acagtataag
     3241 tatgcttata tccgctcccc cggacaatag ccggaatatc taaactaaat cctaaagtag
     3301 gctgtcctcc tacagactcg tgagcaccat tgttaaacaa aatatgataa tagtttttag
     3361 gagataaatc gccaatgtta ctaattgccc ctaaatgcat aataaatgct ccatcaccat
     3421 ccaagcaata aacaggtcta tcttgctttg ctatagcaat acccaaagag attgatgaac
     3481 tatgtcccat agagcctacc gtgagaaaat catgttcatg accttgctct ttcatttctc
     3541 gatattcaaa taactcacga gaaagcttgc cagtagtaga aacgaccact gaattttcag
     3601 gcagataatc cacaactatt tgcaaagcat cctcacgaga taaaggataa ttacatccaa
     3661 actctttttg aagtttatat ttgccaaaaa catctttccg aataattatt gcatgaggaa
     3721 tattcttagt ttttgctgat tgtatgatat catggagctg aataaatgca tcattctcat
     3781 ttgaatcaag aattatataa ggaatccgca ttgctttcaa caaatctaaa gttacctcac
     3841 cctgtttttt atgctgaggt tcatcttttg ttcccggttc accacgccag ccaatcatca
     3901 aaagcattgg aaaactgtat acttgttcat ctgcaagaga cagcagagga ttaacagtat
     3961 tacccaagcc ggaattttgc atataaacca caggaacctt acctgatgcc atataataac
     4021 ctgaagcaat tcctacagcc gcaccttcat tagcagctat gatatgtttc tcacgtgaag
     4081 tatggtctgt gatataggca caaatatttt ttagtaatga gtctggaact cctgtaaaaa
     4141 aatcaacgtc atgactcaga aacgtttcat aaactttttc tacgcttaac ataatgatat
     4201 tcctcttttt atttagtacc tggaatcagt tccaatattt cttttatggg catacacagt
     4261 tcgcgcacct ctaaagcacg ttcattctct aatattgtct ttgcgacatt catcatagca
     4321 ggataagcgg cacgaagcat atgattagca taaataatta tattcacacc ccaatcacac
     4381 aattcagact cataaatatg atcatatgta gtaggcacaa ccacgatagg tacatgagca
     4441 tactgttttc gaaacgccaa acaaaattct tttatatctt cacccgactt atttttgcta
     4501 tgtatcataa taccgtccgc tcccgcttgg acatatgcaa aagctctctc taaagcatca
     4561 cttaccggct ttcccgctat aaggctctca atacgagcga taatcataaa atcatcagta
     4621 atctgagatg cctttcctgc tttgatctta ttacagaaac cttcgattgt atcttgagtt
     4681 tgaataacat ctgtaccaaa caatgaattc ttttttaatc caactttatc ttcaattatt
     4741 atagctgaaa ttccatgacg ttctaaagtg cgtactgtaa atacgaaatg ttcaatttta
     4801 ccacctgtat ctccatcaaa aataataggt ttagtagtac actccagaat attattcaaa
     4861 tcttgcaatc gggtagttaa atcaaccgcc tcaatatcag gtttaccttt actggttgaa
     4921 tccgtaaggc tactagacca cattccgtca aatacttccc tcttatcccc ttttaatatt
     4981 tcctgatttt caattatcaa gccacatagt ccatcatgag cttccaaaat acgaactacg
     5041 ggtttggcat ttatcaaacg acgaagtgat tttaaacgta catcaggggt tgtacctata
     5101 gccttaatat ctttatccaa agaagatgaa ttaattccca aagtatatgg aatttcgata
     5161 acctttcctc cctgttcatt catcacttca aatacgcgca cacgttcttc acgtaaaggc
     5221 ccggttttcc agtcgtcacc atgaattata tagtcaggtt taatgcgttt gagattctca
     5281 acatagctcc attcttcttg aggaacaact ttacatacgc ctttaatatt ctgaactacc
     5341 tcttttcgtt gttcataggt cagataagga aggcgtttat gctccgcaat agctttatct
     5401 gtaagaagac caattataac atcaccgtat ttagtagcct cattaataat gcggataagt
     5461 cctggatgca taatatccgc agtcatccca atataaactg tcttactcat aatttgatat
     5521 attattttaa ttaacaatac ggaacaatat atttctctgc atattccaaa tctgatatgt
     5581 catcgatttc ataccatttc agcccttcta ctttatgcac ataaacagga gattgagaac
     5641 aagatattcg tagtaattca tactcatatc ccaaattggg ttgttcatca acaatactcg
     5701 cataatcagc acacattatt ttgtaaaagg aaccggatag tttatggatg ccgaccaatt
     5761 cgcctttagc gtttagttta ttcttattga cagaacatga agaaaggcga aaattatcat
     5821 catgttccac ataatactga tcttgaaact ttgtcactgg agttattagc attgcatctg
     5881 ccgcaggaca ctccaataag ctcattattg cttgtttctc aaaaatcaaa tctgactcta
     5941 acaataaaaa atcatcattg cccagaatct cccgcgtatt atataaagta tacatactat
     6001 ttgtttcagc ataacgagga ctaaaacagg tttcaagcat aggatagtct gtcttcaatt
     6061 cttcataaac ttcttgttta tatcctgtac cgattacaat tcgctcaatg ccacatgata
     6121 acaaagtatc aatagaacga actatcattg gaatacctcc cactttgacg aaccctttag
     6181 gtatcaattc tgtatattgg ccaaaacggg ttcccatgcc cgcagccatt atcatagctg
     6241 tacgtatcat tcgtttaata atatagtaag tgaatttaat tgatgtaaga atgttgtaaa
     6301 cgacgtttta gcatcattta tcctgttcta tctccttatt tttcagttct tttctcaagc
     6361 tagccagcag acttttgcca aaaagcaccc acacgagagt accagatacg gacaggaaca
     6421 caaataataa aatataaatt ttgagtccca tacctgaagg tttcaaaggt acaacggcag
     6481 gctcaactac tgcaaagact ggcttttcct cctgtacttt ggctctggat acctgcaact
     6541 gattagcaac ctgactatat atctgataag ccaaactcat gtcgttctgt aaacgctcct
     6601 gctcagcacg tacactttga agaaccacat tatcatgggc gtctacataa tccgcatatt
     6661 ttctttgagc agcataatat tcctgctgac gttctttaaa caaccgttcc aaatacgcac
     6721 agtcttcttt tacttttgaa gttcgatacc caataatata ttcctgtaat ttatgaacga
     6781 cagaatctgc tataaccgca gtgatctgcg gattttgtaa ggtgaccgta atgctcgtta
     6841 tggcggtttt cttatcaatg gatgcactaa tcttcttttt aagaaaatta atcttctcat
     6901 ttacttcttt cgtcaattcg atagttcctt gccgccctcc actggcagga accgtatctt
     6961 ctccgaataa tgatttaact cctcctatta ctatgcccgg aaaacctata agataatccc
     7021 accaaggaga tgactcttca tcgagataag accccaaagt cattttatca tcctttttag
     7081 aaacggagac ttccatttct aaaagttcca ataaaaaagg agttgaagaa acaatatctg
     7141 ctgaaagaga agcgttcaag gcatctgtgc tttcccctat tagagcccca tctcccaaaa
     7201 acgaggcagc aagtccggct aaaccattac ttcccttcgc attacccatt tcaggagaag
     7261 ggtaaccttt actgtatatt gcttgggaat gctcaatgcc accactatag caattattac
     7321 tcccactcca gcagctttgc atagtactcc acgaacagta ataatcttat aaaaaatagc
     7381 catcaagtct atttccattt catcatcttt ccttttatcc acttcagaaa acggttcttg
     7441 ataagattgc ttttcaatca taataggtca tttatttctt tatcaaatta gcaatagaag
     7501 caatcatcat tcccaaagaa ctgaaggaag tagcataacc taaaatatta gctatgttcc
     7561 ctttcttctt agccttacca ggcacaataa tctcacaccc cggctcaatc tgtttcttac
     7621 cactaccctt aaccttcgtc acctgaccat tcatgtaaac aatgaacttc ttactcttcc
     7681 ttgcattatc agaacagcca ccggctgatt caggtaataa tccacattct ttcccttcat
     7741 ataagaaacc gtattcggaa ccatgacagc accattgata gttacagtat tagtattctt
     7801 aggtatggag atcacatcac cttcacgtaa gacaagatcg gcattacttt taggattgct
     7861 caaggctttt tccaaatcta ttccaaccgt aaaagtatct tcaacacgaa tacccaaaga
     7921 gtcaatcatg gcctcaccca attgcctgct catcaagcga atcacatcac ccatacgttt
     7981 cttttcacta gcgttagcca cacgggtcag tttcgcacca cgcagatagg cataattggt
     8041 cggaccgccg gctttattca ctaaatcgga aagacgttcc tcacggctgg tcatggcgta
     8101 atttcctccg aaaaggattt caccttcaat ggctacattc tgttgtgcct gatagcccgg
     8161 actgcgacgg acataaacct gatcataagg ctcaaggata aaaccgggct gaccatctat
     8221 tacaaaacca tcctttaaag agaaggtata catctgacca atcgtatcat tatccgcagt
     8281 actacgagga ttcttgattc gtctcgatat atcaatacgg acagtagagg cggcttcttt
     8341 caagccaccg gcctgaatga tcagatcctc aagtgtcatg ttatccgcat aaggatagga
     8401 atcaggttgg gcaacctcac cgtgaactgt gacattaccc cggtcttcca ggtcatggat
     8461 acttggaatg tagaggatgt cattcttcat tagggcaagg tttggggaag tgccgtccat
     8521 gatagactta atgtctatct gaacaacttc actggtcagg tcttcacgct ggcgatagag
     8581 gacggcacga ttcaggaaag cgtcaccggt cagaccctga gcttcatgga caagttcgcg
     8641 gatcgtgttc agtttaccgc tgagctggta gataccggga cgatagacag cgccacggat
     8701 ttccagtttg tttgtgaagc ggttaaggat ggcttcggct gttacaacgt caccgttacg
     8761 cattgtgtag atgctgtagt ccatatcctt gaccgtgttg acctcatatt cctcaccatt
     8821 ctgacggaca acacgcaatg aacgggtgta ggcatcggct tcaaagccgc cggcatattt
     8881 gattaaagtg gcaaggttct cgtctttctt catttcgaaa cgcatagggc gttttacctt
     8941 gccgctgatc tttaccaaga catcataggc ggggacgata accacgtcac cttcctgaag
     9001 gcggatgtca tcctgtgtgt tgcctttcat gataaattcg taaacatcga tggtggcgat
     9061 attctttccg ttgcgtacca actgaacgtt tcggaggctg ccgatatcac tcacgccgcc
     9121 tgcacggtaa agcgcatgga agacggtaga gaaggaagaa agggcgtagg tacccggctg
     9181 cacgacctct cccatcacat tgatctggat agtacggata ttacctaaag tcagacggat
     9241 gtcggaagta gggtcggtag tattgttcag gccgttatag atcttattca gggcgccctt
     9301 cagatagtcg ttggcggcgg agactgtcat accgctaagg ttgacaggcc cgatcttctg
     9361 aatattgatg gtgccttcag gagagatctg ctggcggatc gtattctggc tagcacccca
     9421 gatatcgatg atgacttcat caccgggacc cagacggtaa ttggcaggag tggcaaggtt
     9481 gacactaggc tcgaacgtca ggttgcgggt attgaagata ttgcgcccga aaacctggtc
     9541 ctcacgggcc aaatcttccg tagtcggatg atcttccagc atgtcggaag tattttcctt
     9601 agtctcttca cgaaggcggg actcgttgat atccgtaccc gtggattggg aggtgtttac
     9661 attgttctgc tgctcataga gctgcttcac acgcatagcc tgttccttgg tcacaccttt
     9721 acgcgcaagt tcggaagcaa gctgtttctg ttccttgcct tgccggatgc cgtcctttac
     9781 atattccagt acctgtgagt cactcatgga ctgggccata agcgagccac ttcccagcat
     9841 agaacaaaaa agtagaatgc taaaaagtcg ttgtattttc attgacaaat aaaaaagtta
     9901 gttggtttca cacagttcct gcataccatg acagaccgca gacaactgtt gtttaagaag
     9961 agaaggggga agaacatcaa ggagggtcag agaacgctgc aagacagacc gttttctatc
    10021 ctcgtcttcc ggattggcgt acatcgacac attatatccc tgaaggatgg ccaaacacag
    10081 ggtagcatcc tgctccggtg tcttcccccg ttgtgaatat aaatcgttta tctgtttgtg
    10141 gatggatcgt tgtaaggcgg aaaggtcatc cagatacacg cagcctgcac tccccccacc
    10201 aggaagcagc atgcgtacca aatttaataa accctctatg ttttcctgta aaataacagc
    10261 atccatatcc ctcgccttaa acagccgcca taataggctc tacataaccg acaggcatat
    10321 ccacacaggc acatcccagc atattcaggc gaacggcgat cttactcttg ccatccacat
    10381 gaaccagttc gccaacaaga cccgtcaggg ggcctttaat cacgcggacc ttttcgccac
    10441 gggccaaagg ggcactgttc atgctgatcg attcttcaga ataatcaagc atgaaacgga
    10501 aacgggccat ctgctcgtca ggaattacgg caggactact ctcgccgcgc atcaccatgt
    10561 aacggctcac agtagaaaaa ctcaggactt ccatgcgttc cctagggtca acgtgtacga
    10621 agaccatcat aggaagcaag acggaggtga ccagcttgcg acggtcgctc cattggtgga
    10681 attcctgttg aacgggaacg aaattctcga tacccatctt gtccagatgc tcggaaacct
    10741 tcttttcatg gtgcatccga accaaagcaa cataccagcg ttttgagtgt gctacgcctt
    10801 cccctgtccc attaataggc ccagcattga gtgat
//
