LOCUS       c00035_gnlPro..        16304 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AEKECBJJ_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 19:17:16
            Original ID  :: gnl|Prokka|AEKECBJJ_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16304
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16304
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2752:6304](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2753..6304
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16304
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16304
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(180..1307)
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MAPASARQMASELALLPMWYAEEGSVVLAPSAYNLDYVKKIQELL
                     GLSVDLMTEPELASERNLDIRPWGWDIAIRKRLLDLGVEESELPSIEQLDKLRFCSHRS
                     CAVGLLPQLQLGACFCGESFYLTFPEEWKSFVESHDTCLLKAPLSGSGKGLNWCKGVYT
                     PSISGWCSRIGNQQGGVIGEPLYNKVEDFAMEFRSSGNGRFGFAGYSQFRTGGSGAYEG
                     NLLISDAAIERNLSEYIPVEEIYKLRDRLEQELSLRFGTIYNGYLGVDMMICRFPESPV
                     YRIHPCVEINLRMNMGVVARHIYDHYIYPTSTGAFQISYYPTEGTAWRAHKEMEEAYPL
                     EIEQGRIKSGYLSLVPAHKKSSYRAWVFISKSVFL"
     CDS             1542..2720
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNLNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             2753..6304
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_3"
                     /sec_met_domain="PFOR_II (E-value: 1.3e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.5e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.5e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-12, bitscore:
                     38.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 5.1e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 8.2e-09, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.1e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.5e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNQILEGDNAPAEAKEVLKAWIENMYDADKTKE
                     LAPQIEAIIEQGIAAGCPVSKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPTEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(6457..7323)
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWMVITGWTPHWMFDLFYLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVDSW
                     IPKSENK"
     CDS             complement(7344..8168)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.9; E-value: 6.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.5e-29, bitscore:
                     92.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMIHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSSRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(8165..9391)
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(9690..10028)
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             10112..11407
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKKMTDLEVPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANTSKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNLYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQENQRWWNKPKTNKLIMN"
     CDS             complement(11549..14431)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 62.8; E-value: 1.2e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_9"
                     /sec_met_domain="Peripla_BP_1 (E-value: 4.4e-20, bitscore:
                     62.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYMKWITVLFCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKEMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDILEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQR
                     RMLLLVQRNVNILLRLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAAARKKH
                     IHFSFDYMPDTDYRTLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIR
                     FTVANTGSMISAEHIRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQG
                     TIFTVDLPVQTCETVVSENSPAFSVPATSVTSTDAATSAVAGAPVTPATSGYSGSSSLN
                     DALTYEEEELEKSYDSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAAYGSEGIRKAMK
                     YVPDLIISDVMMPGMDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYI
                     SKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGD
                     SNLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGY
                     EVGFSSPSYFTKCYREQFGESPTDLLKRKG"
ORIGIN
        1 tgagtaaact aacttaggta taacaagcga agttgtcaac taaatccagt acagtacaca
       61 catggcatgt gattacttgt ttcatgcaat aaaacttttt gtttctcggt gtggaaccaa
      121 tggtttcact acatgaaact atcagtttca caccgagaaa ccataacttc gatataatat
      181 cacaaaaaca cgctttttga gataaacacc cacgcccgat aactactctt tttatgagcc
      241 ggcaccaatg acaaatagcc tgattttatt cttccttgtt ctatttccaa aggataagcc
      301 tcctccattt ctttgtgtgc tctccaggct gttccttccg tagggtaata gcttatttga
      361 aaagctcctg ttgaagtagg atagatataa tggtcataaa tatgacgcgc tactactccc
      421 atattcatcc tcaagttgat ttccacgcaa ggatgaatcc gataaacagg agattctgga
      481 aagcgacaga tcatcatatc cactcccaaa taaccattat aaatggttcc gaaacggagg
      541 gataattctt gttcaaggcg gtcgcgcaat ttataaattt cttcgacagg gatatattcc
      601 gaaagattcc gttcgatggc tgcatctgaa atcagcagat taccttcgta cgccccactt
      661 ccacccgtac ggaattgaga gtatccggca aaaccaaatc gaccattacc cgaagaacga
      721 aattccatag caaaatcttc caccttatta tatagaggtt cgccaataac acctccttgc
      781 tggttgccaa tgcgtgagca ccaaccggaa atggaaggag tatatacacc tttgcaccaa
      841 ttcaaccctt ttccgctacc ggataaagga gctttcagta aacaagtatc atgtgattct
      901 acaaatgact tccattcttc gggaaacgtc aggtaaaaag actctccaca aaaacaggct
      961 cccagttgta gctgtggtaa taatcccaca gcacaggaac gatgggaaca gaaacgcagt
     1021 ttatccaatt gctcaataga aggaagctcg ctttcttcca ctcccaaatc caacagtcgt
     1081 tttcttattg ctatatccca gccccaagga cgaatatcca aattccgctc cgaagcaagt
     1141 tcaggttctg tcatcaaatc aaccgaaagt cctaataatt cctgtatctt cttcacatag
     1201 tcgagattat aagcggaagg agccaataca acacttccct cttctgcata ccacatcggc
     1261 aacaaagcca attcggatgc catctgccgg gcggaagccg gtgccatata gtttgtttca
     1321 ccgctggcta acgccaaatc atgttccgga ttgaatatat aaagagcctt ttttgtcatt
     1381 ttaaacgaat tcaaaacttt attctgcaaa tatatacagg aaatagtcag gaatggctac
     1441 aataaacaga aagttctaat taaactcaca attttgccat ctctactttg caaatcctaa
     1501 aaaaagcagt atatttgcca cccgaaaaac aaagaactga aatggaatca ttctatcgca
     1561 cacacgccta cctcgttgag cacaccaatg cccccgttcg ccgcgatctt atggacgaga
     1621 tcgactggag cgaccgcctg attggtatca aagggacacg tggcgtagga aaaaccactt
     1681 tccttctcca atacgccaaa gaaaaatttg ggaacgaccg ctcctgcctg ttcatcaaca
     1741 tgaacaactt ctacttctct ggccacagca ttgtagactt tgctaacgaa ttccagaaac
     1801 gtggtggaaa agtattgttg atcgaccaag tgttcaaaca cccggaatgg agcagagagt
     1861 tgcgcatgtg ttacgaccgt tttcctaatt tgaaaattgt ctttaccggc tcatctgtaa
     1921 tgcgactgaa agaggaaaat cttgaattgc gtgatattgc aaaaagctat aacctgcgcg
     1981 gattttcttt ccgcgaatac ctgaacttac aaacaggcat gaaattcagg gcctacagtc
     2041 tcgaagaaat tcttagcact cacgaacaga ttgccaaagg agtactctct aaagttcgtc
     2101 cgctggatta cttccaggat tacctgcatc atgggttcta tccattcttc ctcgagaagc
     2161 gtaacttttc ggagaatttg ctgaaaacga tgaacatgat ggtggaagta gatatcctgc
     2221 tcatcaaaca aattgaactg aaatatcttt caaagataaa aaaattacta tatttgctcg
     2281 ctgtcgacgg accgaaggct cccaatgtga gtcaactggc aagcgacata cagacatctc
     2341 gcgccacggt gatgaactat atcaagtatc tggcagatgc gcgactcatt aatctggttt
     2401 atccgaaagg agaagaattt cctaaaaaac cttccaagat aatgatgcac aactccaacc
     2461 tgatgtattc catctatcct gtgaaagtgg aggagcagga tgtactcgac acattctttg
     2521 caaattcttt atggaaagac cataaggtac ataaaggaga taaaaacgtc tcttttatgg
     2581 tggacgaagt aatgccgttc aaaatttgcc aggaaggagc aaagatcaag aacaatctga
     2641 atgtgacgta cgcgttgcat aaggctgaaa taggtcgggg caaccagata cctctctgga
     2701 tgttcggctt tttatattaa aagatttatt tacttaaata tttaatttag ttatgactaa
     2761 acagaagaaa ttcatcactt gtgatggtaa ccaggctgca gcgcatatct cgtatatgtt
     2821 ctctgaagta gctgctatct accccatcac tccttcttcg actatggctg agtacgtaga
     2881 cgaatgggct gccgcaggac gtaagaacat cttcggcgaa acagtattgg tacaggaaat
     2941 gcaatctgaa ggtggtgctg ccggtgcagt tcacggttct cttcaggctg gtgcgttgac
     3001 tactacttac actgcttctc aggggcttct cctgatgatc cctaatatgt acaaaattgc
     3061 cggtgagttc ttgccttgcg tattccatgt atctgctcgt acattggctt ctcacgcatt
     3121 gtgtatcttc ggtgaccacc aagacgtaat gtcagctcgt cagactggct ttgcgatgtt
     3181 ggctgaaggc tctgtacagg aagttatgga tttggctggt gttgctcact tggctaccat
     3241 caaatctcgc gttccgttca tgaacttctt cgatggtttc cgtacatctc acgaaatcca
     3301 gaagattgaa atgttggaaa atgatgatct tgctccgctg atcgatcagg aagctttggc
     3361 tgaattccgt gcccgcgcac tgaatccgat gaatccggtt gctcgtggta tggctgaaaa
     3421 ccccgaccac ttcttccaac atcgtgaatc atgtaacaac tactatgaag cagttcctgc
     3481 tatcgtagaa gaatacatga atgaaatttc taagattaca ggtcgtaaat acggtttgtt
     3541 cgattattat ggtgcagaag atgcagaacg cgtaattatc gctatgggtt ctgtaacaga
     3601 agctgcccgc gaagctatcg accacttggt agcaaatggc gaaaaagtgg gtatggttgc
     3661 cgtacacctg tatcgtccgt tctctgctaa acacttcctg gctgctgtac ctaagactgc
     3721 caagactatc gcagttcttg accgtactaa agaaccgggc gctaacggcg aacctcttta
     3781 ccttgacgtt aaagactgct tctacggcgc agaaaatgct ccggttatcg ttggcggtcg
     3841 ctacggtttg ggttcaaaag atactactcc tgctcaaatt ctttcagtat tcgaaaactt
     3901 ggccatgcca atgccgaaga atcacttcac tatcggtatc gtagacgacg ttactttcac
     3961 ttctcttcct caaaaagaag aaatcgcttt aggcggtgaa ggaatgttcg aagctaaatt
     4021 ctacggtttg ggtgctgacg gtacagtagg tgctaacaag aactctgtaa agattatcgg
     4081 tgacaacact gacaaacact gccaggctta cttctcttat gactctaaga agtcaggtgg
     4141 tttcacttgt tctcacttgc gtttcggtga tactccgatc cgttccactt atttggtaaa
     4201 tactccgaac ttcgttgctt gtcacgttca ggcttacctg cacatgtacg atgtaactcg
     4261 tggtttgcgt aagaacggtt ctttcttgct gaacactatc tgggaaggtg aagaactggc
     4321 taagaacctg cctaacaagg ttaagaaata ttttgcacag aacaacattt ccgtatacta
     4381 tatcaacgca acacagattg cattggaaat tggtttgggt aatcgtacca acactatcct
     4441 tcaatctgca ttcttccgta tcacaggtgt tattcctgta gaccaggctg ttgaacagat
     4501 gaagaaattc atcgttaagt cttacggtaa gaagggtgaa gacgttgtta acaagaacta
     4561 tgctgccgtt gaccgtggtg gtgaatacaa gactttagct gttgatcctg cttgggctaa
     4621 cctgccggat gatgcaaaag ctgaaaacaa cgatcctgca ttcatcaacg aagtagttcg
     4681 tccgatcaat gcacaagatg gtgacttgct gcctgtatct gcattcaagg gtatcgaaga
     4741 cggtacttgg tatcaaggta cttctaaata cgaaaaacgt ggtgtagccg cattcgttcc
     4801 tgaatggaat ccagaaaact gtatccagtg taacaagtgt gcatacgttt gtcctcacgc
     4861 ttctatccgt ccgttcgtac tcgatgctga agagcagaag ggtgctaagt tcgaacaatt
     4921 gaaagcagta ggtaaagtat tcgacggtat gacattccgt atccaggttg acgttctcga
     4981 ctgtctgggt tgcggtaact gtgctgacat ctgtccgggt aatccgaaga agggtggcaa
     5041 agcattgaca atgaaacacc tcgaaagcca attggctgaa gctgacaact ggacttactg
     5101 tgctgaaaac gtgaagacta aacaacatct tgttgatatc aagtctaacg tgaagaactc
     5161 acagttcgct actccgttgt ttgagttctc tggtgcttgc tctggttgtg gtgaaactcc
     5221 gtatgtgaaa ttgatttctc aattgttcgg tgaccgtgaa atggttgcta acgctaccgg
     5281 atgttcttct atctactctg gttcagttcc ttctactccg tatactacga acgaaaacgg
     5341 tcacggtcct gcttgggcta actcactgtt cgaagacttc tgtgaattcg gtctgggtat
     5401 ggaattggct aacgaaaaga tgcgtgctcg tatcgtgaag ttattcaacc agattttgga
     5461 aggcgataac gctcctgctg aagctaaaga agtattgaag gcatggattg aaaacatgta
     5521 cgatgctgac aagacaaaag aattggctcc tcaaatcgaa gctatcatcg aacaaggtat
     5581 cgctgccgga tgtcctgtta gcaaagaact gaaaggtctg actcaatatc ttgtaaaacg
     5641 cagccagtgg atcattggtg gtgacggtgc ttcttacgat atcggttacg gtggtcttga
     5701 ccatgtaatc gcttccggta aggacgttaa cattctcgtt ctggatactg aagtttactc
     5761 taacacaggt ggtcagtctt ctaaagctac tccggtaggt gctatcgcta agttcgctgc
     5821 tgctggtaag cgcgtacgta agaaagacct cggtctgatg gctactactt acggttatgt
     5881 atatgttgca cagatcgcta tgggtgctga ccaagctcaa actctgaaag ctatccgtga
     5941 agctgaagca tatccgggac catctttgat tatcgcttac gctccatgta tcaaccacgg
     6001 tctgaaagca ggtatgggta agagccagga agaagaagaa aaagctgtta agtgcggtta
     6061 ctggcacttg tggcgttaca acccagcttt ggaagaagaa ggcaagaacc cattccaatt
     6121 ggatagcaaa gaaccgaact gggaagattt ccaaggtttc ttgaagggtg aagttcgtta
     6181 cgcttctgta atgaaacaat atcctactga agctgaagaa ctgtttaaag ctgctgaaga
     6241 aaacgctaaa tggcgttaca acagctacaa acgtttggct agagaaaact ggggtgctga
     6301 ataatagtaa taccctataa atataaagcg gtaatctttg ataagattac cgctttttta
     6361 ttgtatgaac tctgtccaac ataaacagta ctcccttttt cccactagag ttcatgtcta
     6421 ttttatattt aaaattaaaa ataacaatgc tccaatctat ttattctctg acttcggaat
     6481 ccaactatcc accaacagcc gatgctcatc cctccatttg cgggctattt cttcttcatc
     6541 catccgggca tccttcatag ctgtcataaa agagctaagt tcttctgtcg ttagtttgat
     6601 gttgccaaag aattcggcag caaacggatc tttctcactg aatcctttcc atgcaatagc
     6661 atgtatttct tccaagtctc catatacttt cttcggatca tccaagaatt tcaaataaaa
     6721 caggtcaaac atccaatgtg gtgtccaccc cgtgatgacc atccattctc ctttatccat
     6781 cgcttttttc aaagaagcca gcatggtgga actacttgaa gtcatgaggg tatacccatc
     6841 aagtccgtaa gcagcaatgg ccttatcggt cgtcttcatt atccctgctc ccgcatcaat
     6901 tcctactatt tcagaagaga aacggtcttt attagcttcc agctcactaa tagactggat
     6961 cgtaacatat tgaggaacaa ctagtcctac acgggcctct ccatatacct cacccagaaa
     7021 ttcgatactg tctccatact gatccatata atctttcatc gttattggta accatgcatc
     7081 cagaaacaca tctgatttct ttcctgacat agatacaaaa ataggggcaa gatcagcatt
     7141 ttgcaattca acctcatatc catgctcttc caataccacc ttagccaaat gactcatggc
     7201 aataccttcc agccaattgg cataggctat ttttactttc tttttctcta agtctgaatt
     7261 agtacaggaa gctagcaaaa gcatagctga caatactatt cctactattt tatatattct
     7321 catacgtatt ttatcctttc cgtttagttc ttattttttc gtcctgccat tccttgcgtg
     7381 atacggtcta agatgatagc taaaataaca actgctatac caccttcaaa cccaagtccg
     7441 attttcattt gggtaatacc tttcaataca atttctccca gaccaccggc agcaatcatg
     7501 gcagcaatta caaccataga aagcgacatc attattgtct ggttgacacc agtcagaatg
     7561 gtgggcaacg ccaaaggaag ctgcacttta tacaataact gccaacgggt agctccgaac
     7621 gaacgggaag cttccactac atttttagga acttgccgga ttcccaatcc ggtaaggcgg
     7681 accacaggag gcatagcaaa gataatggtg gcaaacactc ctggcactgc tcccaatccg
     7741 aaaaacaaaa cagcaggaat cagataaaca aaagcaggca tcgtctgcat caagtcgaga
     7801 acaggacgga gtattttctc tgcacgcgaa ctgtttgccg tccatactcc taaaggtaca
     7861 ccaacaatca gggccagaca ggtagatgaa aaaacgagag ctagagtttg catggtagcc
     7921 tcccagaatc ccattccata gatcagtaat aatcccaatg cggtgaaaat tgccgtaccg
     7981 cgtcctgctt tcatccatgc gagtgcagca agtaccaaaa tggttatata aaaaggtatt
     8041 ccgaaaagta tgtgttggaa tcctataata aaactaccga tgcccgcatt cacggcatca
     8101 aagaaagtgg aaaaatgtat catcatccaa ttgatggcca tctctatata ttgtcctata
     8161 tttatcataa atctattgcg ttttgaatta tttcgtttat ttcttcttta tctttcccgg
     8221 tcacttcgat gattaaggat gaaagcggga ttgttcctaa aaactcgcgc gtctcatcaa
     8281 tcacccatac cggcgaattg ctctttgtca ttagaggaag tatatcctcc aacaccgtat
     8341 cctccaacac agaatgtact tctgtacgca caatcgtttc aatggatttt tcctgtttgc
     8401 tacgtaactt aagcaagtcg ttcagacgta cttctccgac cagtttatca tcggcgtcta
     8461 tgacaggtaa tacggtgata ttcttcgcac gcatcttacg aatcaatact tcgggacctt
     8521 ctttcttcag acgggccacc aacggtttgt caatcattaa agaagaggcg gtaataattt
     8581 tgctcctatc cacgttttca acaaaacggg ctacataatc gttagccggt tcagtcagga
     8641 tttcctccga agtacctacc tgcaccactt ctccgtcttt catgatggca atacggtcac
     8701 ctagcttaat tgcttcactc aagtcgtggg taataaaaac aatcgtcttt ttcatctttg
     8761 attgcaaggc cagtagttca tcctgcatct gtacgcgaat cagaggatcg agagcagaga
     8821 aagcctcatc cattaaaagc acttcaggat tattagccag agcgcgagcc agtccgacac
     8881 gctgttgcat tccaccggaa agctcgccta ccatctgatt ttcatatcct ttcaatccga
     8941 caagcttcat gctttccatc gctttcttct cacgttcctc tttcttcact ccctgaagtt
     9001 cgaggccgaa cgcgatattg ctcaatacgg aacggtgagg taacagaccg aaattctgga
     9061 aaaccatcgc cagctctttc cgacgaacct gcaataattc tttttcggaa attttagata
     9121 tatctactcc gtttacaagc acttgcccgg tagtaggacg tatcagacga ttgatacaac
     9181 gcagtaatgt cgattttcca cttcccgaga gtcccattat cacgaaaaac tctccttcat
     9241 taattgaaag attggcatct ttcactccta ccgtacaacc ggtatctttc agaatttcct
     9301 ctttactctt atcttttttc aacatcttga gggctttctg cttctcgtta ccaaagataa
     9361 ggtacaaatc ctttatttct attttactca tataatatat tggtttagat tataatattt
     9421 gttttgtttt caactgccgc attccttatt ctcacttacg ataaacaagt tgaatgttcg
     9481 catggttcag tcatgtcaca tgataacatg acggtccgac gttttttaaa tggttaaaaa
     9541 aaacagacag agtagtttaa aaggaataga atttgataag attatcctct taatgaacag
     9601 tagaaaacag tattttcata aataaataac agtctgttct tgcatattgt tggcacaaag
     9661 gtaaggaaaa tagattaaat atgcaaattt cattcaggta cggagtaatt ccaaagatgc
     9721 tttttcaagt ctacgcatcc attttgtttg aaagagatcc cttcttccaa caagagttgt
     9781 ttctgctctg tccaacccgg aacaagccgt cccgacgcat tgacaacccg atgacaaggc
     9841 gcagataaat catccggaat ctgtttcaaa gcacgcccca ccatacggga acattgagac
     9901 attcccaata atgcggcaat tcccccatag gtagaaactt tacctaccgg aatttctcgg
     9961 acaacctgat acacctcttg acaaaaggat gcggaaaggc tcgccttatc tactttataa
    10021 tctttcatca ctcaaacatt actttatttc agttccaaaa ctagataaaa agaaaagaat
    10081 ttgcaaataa taaaagcatt tcaaataaaa tatgcaactt tatttgcttt atttacaaat
    10141 aatcccgacc tttgtaccca ttaaaagcaa ccctattatt aacaaaacaa gcactgctgt
    10201 tatgaaaaag aaaactatcc tgttcgcttc ttgtttattg ggagcactgg ctttcagctc
    10261 ctgtgagaag aacctttatg atgaaagtaa acaacccgag aaagaaaaga agatgactga
    10321 cttggaagta cctgccgatt tcgactggaa aggttctcaa aatgccaaag tgaaaattgc
    10381 cagtcaatca actgctacta tttctgtatt tctagaagaa aattgcaatg aagaggcttt
    10441 gatgcttcga atggatgtcg atgccaacac atcaaaattg gaactcccaa ttgaaattcc
    10501 tgcatatata aaaaatgtgt atgtaaaata tggtaatggc tctgaaatac aaactgttcc
    10561 tgttgaaagt aatggtacta tttctatagt agtacctgct aacgctacgg cattatccag
    10621 agttaccaca agagctaata aagaagttga aacgaacaac atcttcaatt atccgggata
    10681 tggcaacgga actattatgt tcgaagatat gtatccagct ttaggcgatt atgattttaa
    10741 tgattttgtt gcatggtata atttccaaat tgacggtttt tattggagtc acaatcaatg
    10801 ttatgcagaa tacttaatga taggattcca aatcagagct ataggaggta tatatgacta
    10861 caatctttat atccgcttgg cagaagtaca atataatgaa cttgatttag aagaaactca
    10921 aatgtatctt gagcgtaaca atcctgaaga ggctgaaaat atcaaaatcc taaaaggccc
    10981 aaaaggggaa ttgattattt cactaaagaa accggccatt cctaacggat acaagtatta
    11041 taatacggag gtaaatgaaa aaacaaagcc taaaaaaatg atggccattt acttggtgtt
    11101 caactcacct gttaacgtta aaagcctaca agacagtaaa atggactttt atattgcaaa
    11161 aactaataaa ggacaagaaa tccacttaaa aggttatagc ccggtttatt ataacagcaa
    11221 cgaaagttat gtaaatgaag acaactttat atggggatta aaagtacctg catctttaca
    11281 tcatgccaga gaagaagtaa acttcttgga agcatatcca gactttgaac aatgggtaac
    11341 atcgggaggt caagagaacc aaagatggtg gaataagcca aaaacgaata agttgattat
    11401 gaattaataa atatacagta aatcatatac tgaattaaat aagaggtaag gtatgtcaat
    11461 agatttcctt acctcttatt tttatcatat gaattccata gaagtataaa cagataaatg
    11521 ctcaccacca aattttgcag attctatcct atcctttcct cttcaacaaa tctgtcggac
    11581 tctctccaaa ctgttctcta taacatttag taaaataaga aggagaacta aaaccaactt
    11641 cataaccgat ctctgccact gtcatatccg acgaggcaag cagagaggca gctttcttca
    11701 aacgagctat acgaagcagt tcattcggag aataattagt cagagattta atcttgcggt
    11761 aaagttgcac acgacttaat cccatatcct tacccaaatc ttctacattc aaatttgaat
    11821 ctcccatctt tgcctcaatc agagctttga atttttccac aaagtcttta tccatatcac
    11881 agacatcctc tttcgccaac gtttgtccgt caccaaaaaa ctgtttcagg cggcggtgtg
    11941 aatctatcag attacgaacg cgtgccaata gtaattgcga actgaaaggc ttggagatat
    12001 aagaatctgc accaccatca tacccttgaa ttcgttgttc atccaaagaa caagctgtca
    12061 ataggataac aggaatatga caggtttgta attcgctttt caagcgacga caacattcaa
    12121 ttccatccat tccgggcatc attacatcgg agataatcaa gtccgggaca tatttcatag
    12181 ctttacgaat accttccgag ccgtatgcag cttctataac agtataatca gtgtgaagca
    12241 atccatgcac atataagcga atatcagcgt tatcatcaat aatcagaacg caaggtttgg
    12301 aagagtcgta acttttttcc aattcctctt cttcgtaagt taaagcatca ttcaagctcg
    12361 aagaaccgga ataaccagaa gttgcaggag ttacgggagc cccagcaacg gcagaggttg
    12421 cagcatcggt agaggttaca gaagtagcag gcacagagaa tgccggagag ttttctgaaa
    12481 caacagtctc gcaagtctgt acaggcaaat caacggtaaa gatagttcct tgcttttcat
    12541 cactttccac cgtgatggta cctttatgca attccacaaa agcctttacc aatgccagtc
    12601 caatacccga accggcatgg tgcatatcta tcttatagaa acggtcgaaa atattccgga
    12661 tatgctccgc agaaatcatt gagccggtat tggcaacagt aaagcgaatc caacaatgat
    12721 cgtctttagt cagggaagat aagcgtacag ttacttttcc attctctgga gtaaatttga
    12781 aagcgttgga aaggaggttg aaatagatgc gttccaactt ttctacatct gccaatgtgc
    12841 ggtaatccgt atccggcata taatcgaatg agaaatgaat atgtttcttc cgggctgctg
    12901 ccatgaaaga ctcgttccat ccctcaaaag aagaaagaat gtctaacgaa ataggagtat
    12961 attccatttt tccattctcg tatttacgaa aatccagaat ctgattgaca agacgcaaga
    13021 ggatattcac gtttcgctga actaacaata acattcggcg ctgatcttca ctcaaagacg
    13081 aatcagccag taaatgctct accgggtcgg caactaatgt cagtggagta cgaaaatcgt
    13141 gagatatatt tgtgaagaaa accagcttgg catgagtcgc ttcttccagt tgatgagaaa
    13201 gctggataag ctgatcccgc tgttcttcga gtttgtcacg ctgttcttca agaatatccc
    13261 gttgctcttc gagtttatcg cgctgttgct ctacttgttt cttctgttcg gacaactctt
    13321 tattcaggcg attcttggaa cggagggatt tatagactac caacaacaat cccgctacta
    13381 ataaaagaat aaccaagccg ccatacatca cgacctgctg cgtagctaca cgcgacagat
    13441 acccaccgat acgtccgttc aatgtttcaa tcttctgatc cagttccgag atatgggtag
    13501 tctgaagttg cataacgtgc gcgttcgtgc ggtctacaac ggcagtattc atgaccgttt
    13561 cgcgaggata agacttcttc tcaagaatat tcatggccag ttgcatcact ttgtccccat
    13621 tagtcggata aataaaagtt gcatccagca cattgtcaag caccaattca agcccgtttc
    13681 ctttgccggg cagggcatca atgccaacaa aaatcatttc cttttcacgt ccggctttct
    13741 tcgcagcttg ataggctccc ggagcgatac ggtcgttatg tgcatatacc gcatcaatct
    13801 tcggatgacg gcgaagcata ctatccattt ccacttctgc cggttcacgt tcccaggcag
    13861 catccgcttt atcaatcagt ttgatatccg gataattgct gatagcagcc ataaatccct
    13921 gatggcgttc catggcaggg gtggaaccac ccagtccggt aagctccact acattccctt
    13981 tccctttcag acttgatgcg atataatttc ctaccgcacg acctatttca taattatcgg
    14041 caccgatata ggcagtatat ttatcagaaa gtatcttccg gtctacaaga atgacaggta
    14101 ttcctttctg ataggcctcc tccacaattg gagtcatggg agccgcttca ttggcggaaa
    14161 ttatcagtaa atcaactcct ttatctataa aataatgaac atcttccgcc tgcttacggt
    14221 tatcatccgc cgccgagcgg atttcaaccg acactccatc ataaaacatc gcttcgcgaa
    14281 gaatctcatc attcatcttg tgccgccaag agtcatcact acattgggcc accccaatac
    14341 ggaaacgagg cgcatcctga cgacaggccg ccaagcccaa aagacaaaac aagactgtta
    14401 tccacttcat atatttcatc gcttcaatca ttccctttct ttcgtatatc ttttgtattt
    14461 ctttctgtaa tccaaatttc tctccccgca ttatttgcat tcaccaccgg gaaatacatc
    14521 agttccactt tcacagggtt cagcgtgtat tttccagtaa agcgtgaaag caaaggaacc
    14581 gtaaactgat aagtacctac cggtaatttt tcgctaaaga taacagtttt ctctttaaaa
    14641 tactcacgat atacttcaga acgggagaaa ttaacaggtt ttgaggcata actacaacct
    14701 gccggaacag gaacttcgag catcacatat tgcgcaccct cctgtttcac ctgcaaggta
    14761 actgtcaatg taacaggtac acccgccacc aaagagtctt tttccaaagt cgcctccacc
    14821 ttgaaagcat cactctgacg agcattcatc acacgcttca ttgaatagac actatacaat
    14881 aaaggctctt ttcccgtttt tgaaataagc agactgtcgc ctgctatcag ccgggcatga
    14941 taaggaaatt ccgtaattcg ttgatgatcc ttaccgctca cagacaccga cgttcctgac
    15001 atccctccgg aacctgccag caaatcggtc agaacagttg ccacagccga agaagcctga
    15061 tacgtattcc atccgcgctc cttagtccgc aaaatataca attgcatatt ttctttcaac
    15121 ttacacaggg aagggtcatt tttaataatc cggtaggcta tcaatgtatt tatcatctga
    15181 tttccctccc aataataagt acgccgtccg tcgtcacagt aaacaccttc cagcatatcc
    15241 tttttcagat aaggacgtac gctatcaccc acattcaccg aatccacctg ttgcttgatt
    15301 tcccagagaa gcagcttctc tttcaagtat gaaagaggac gataatactt gtttctattt
    15361 gccaacgagt cttctttctg ttccaattgc cggacgaaag gttccaataa tctgactgcc
    15421 gaagaataat ccgcctctac tttccactca tgcagagcat gaagtatttc tatatcttcc
    15481 agtttcattc ctcgataagg acgcgtatga gcatactcca ctttcaaacc attcagattc
    15541 aactccacag gataacctgc atcttgcgcc atcttcaaag cccgcagaat atgcgcagac
    15601 atccagaaag aagtattttc agagttcccc caccacgacc ataactgatg tttgttctga
    15661 tgattcgtca gtcgatggat gataggtcga attgctttat ctactttcac cttttcaccc
    15721 ttactctgca tatactgttg gtaagccaac aaaccgatta acttggatgc cagctgctca
    15781 ttgcacaaat atttgtatcc tgtcaagtaa ttcactgatt ctttatagat gtccaactga
    15841 ttgtcagtga tactcaccat cacttcttca tcctcgccgg attgcacttt gaccgtcttt
    15901 gcatcggaca gaatacccaa tgtgccctcc gccaattcag ttccctgtgg cagtatcgga
    15961 atcgtatatt cctctccatc ctgatagcca tcgtcgcgag tgaaaagata gctgatggtc
    16021 acgctatcgg catgaactgc ctgcatcggc actgtttcat gaaatccctc catgaaactc
    16081 acttcctgcc gtttcaacgt atccgttccg acgcagaact gtgtctttcc ggctatgtgc
    16141 tgcccatcca gataattgcg gatagtccca accaccgtac tctgatcccc ctccaccagg
    16201 aagcggggag ttttcaactc cgccatcaac ggtttgtaag agcggatgga acgtcggaaa
    16261 gtacccgtct gcaaacgacg gttcatgcca taaacgacag tttc
//
