LOCUS       c00167_gnlPro..        11641 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LBCIKNEF_167.
ACCESSION   c00167_gnlPro..
VERSION     c00167_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 19:12:11
            Original ID  :: gnl|Prokka|LBCIKNEF_167
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11641
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11641
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[625:1641]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      626..1641
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11641
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11641
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             251..469
                     /locus_tag="ctg167_1"
                     /transl_table=11
                     /translation="MNKSEIGLNAGKVWQLLSDYTRWSYGSLKRKSGLKDKELGAALGW
                     LAREDKIEIHQEEDELYVSLGVNVYIG"
     CDS             626..1162
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg167_2"
                     /sec_met_domain="Beta_elim_lyase (E-value: 6.6e-35,
                     bitscore: 110.3, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSFASDNNSGVHPLVMEALNRANSDHAVGYGDDPWTEEAVRKIR
                     EAFTPDCEPLFVFNGTGSNAVALQLCTRPYNSIICAETAHIYVDECGAPARMTGCQIRP
                     IATPDGKLTPDLVRPYLCHFGEQHHSQPGAIYISQCSELGTVYKPDELRALTDLAHRHG
                     MYIWTEHVWQMLVQP"
     CDS             1123..1641
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg167_3"
                     /sec_met_domain="Beta_elim_lyase (E-value: 8.2e-17,
                     bitscore: 50.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGARLANACAALNLGFRELTVDCGIDILSFGGTKNGLMLGESVV
                     VFNPALKKEAYFVRKQSAQLASKLRYLSCQFTAYLTDSLWLKNAAHANRMAKILYDGLK
                     ELPGAHFTQKVESNQLFLTMPRPVIDELLKDYFFYFWDEAIHEIRFVTSFDTTEEDIEQ
                     LLQSVKRLL"
     CDS             complement(1813..4323)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_deac_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg167_4"
                     /sec_met_domain="Polysacc_deac_1 (E-value: 2.4e-18,
                     bitscore: 55.9, seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSNYWLLTVIFALVALPGKAGEWIRINQLGYLPQSVKVAVFMSE
                     EGTNVENYSLIDAFTGKVVRTFNTTKATGKMGGMKSTYRLNFSDFTEPGTYYLKAGKAV
                     SPRFPINAQVYNGTADYLLHYMRQQRCGYNPFLKDSCHVHDGYIVYHPTKTGQHIDVRG
                     GWHDATDYLQYTTTSANAIYQMMFAYQENPESFGDAYDAAGHPGANGIPDIVDEIKWGL
                     DWLNRMNPAPGELYNQIADDRDHAGMRLPNKDLVDYGYGPGKGRPVYFCSGEPQVRGEF
                     KNATTGVASTAGKFASCFALGAKILKDYYPEFAAEIEAKADAAYQEGVKKPGACQTASV
                     LSPYIYEEDNWVDDMELGAMELYKATGDNKYLAQALEYGRREPVTPWMGADSARHYQWY
                     PFMNMGHYHLAKVDNSRISKEFIRNMRTGIERTYEKAVESPFLHGIPYIWCSNNLTTAM
                     LTQCRLYRETTGDDTYAEMEASLRDWLFGCNPWGTSMIVELPLYGDYPSQPHSSLLNAG
                     VGNTTGGLVDGPVYRTIFESLRGVNMTGIPGTPGQDYERFQPDLMVYHDAIHDYSTNEP
                     TMDGTACLTYYLSAMQKDGMKQAGIPNDKNVYVDGGIIRTDPSKKQITLVFTAADKADG
                     ADAIISTLKKHGIKGGFFFTGEFYELYPDVVKRLLDEGHFVGSHSYGHLLYMPWEDRDS
                     LLVTREEFENDMMKSYETLRKAGIEYKDAPVYIPPYEYYNKEISAWAKNMGIQVINYTP
                     GTMSNADYTTPDMGQKYRSSKFIYDKIMEVEKKEGLNGHLMLIHFGTDDRRTDKFYNGY
                     LDKMIKTLKRKGYTFVPVREAVGI"
     CDS             4632..5600
                     /locus_tag="ctg167_5"
                     /transl_table=11
                     /translation="MAYIDYYQVLGVDKKASQDDIKRAFRKLARKYHPDLNPNDATAKD
                     KFQAINEANEVLSDPEKRKKYDEYGEHWKHADEFEAQKRAQQQAGGFGGFGGAGFGGSG
                     AGFGTDGGGTYWYSSDGQEFSGSNAGGFSDFFEQMFGHRTRGGGGANAGFRGQDYHADL
                     NLSLREAAKTHKQILTVNGKQVRITIPAGVANGQVIKLKGYGGEGINGGPAGDLYITFV
                     IPDDSVFKRLGDDLYVDVTVDLYTALLGGDQLVDTLDGQVKLKVKPETQNGTKVRLKGK
                     GFPVYKKEGQFGDLIVTYSVKLPTNLTEQQKEMFRKIQSMN"
     CDS             5600..5911
                     /locus_tag="ctg167_6"
                     /transl_table=11
                     /translation="MKGERIMQNEWIVISEYCDKCHIEPTFIDMLCESGLIDVEQEGGE
                     RYLPFSELPDVERYSRMYYDLSINMEGIDAIHHLLARMEEMQREIHSLRGRLRLHGEY"
     CDS             complement(6049..7755)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg167_7"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.5e-33, bitscore:
                     105.0, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.7e-29, bitscore:
                     90.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 7.7e-16, bitscore:
                     48.4, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANFYTEVPELKYHLNNSMMERICELKERGYQDKDKYDYAPQDYA
                     DAMDSFDKVLEITGEITGEIIAPNAEGVDEEGPHCANGRVEYASGTKQNLDAMVKAGLN
                     GMTMPRRFGGLNFPITPYTMCAEIVAAADAGFGNIWSLQDCIETLYEFGNEDQHSRFIP
                     RVCAGETMSMDLTEPDAGSDLQSVMLKATYDEANNCWRLNGVKRFITNGDANLHLVLAR
                     SEEGTKDGRGLSMFIYDKNEGGVDVRRIENKLGIHGSPTCELVYKNAKAELCGDRKLGL
                     IKYVMALMNGARLGIAAQSVGLSQAAYNEGLAYAKDRKQFGKAIIEFPAVYDMLAIMKA
                     KLDAGRSLLYQTSRYVDIYKALDDIARERKLTPEERQEQKKYAKLADAFTPLAKGMNSE
                     YANQNAYDSIQIHGGSGFMLEYACQRIYRDARITSIYEGTTQLQTVAAIRYVTNGSYSA
                     TLRDYEQVPCSEEMQPLMDRIKEMTNKFEACTNAVKEAQNQELLDFVARRLYEMAAVCI
                     MSHLIIQDATKAPELFGKSALVYVNYAEAEVEKHFNFIRKFKAEELESYRK"
     CDS             complement(7766..8836)
                     /locus_tag="ctg167_8"
                     /transl_table=11
                     /translation="MKGLILIFVLLSGISSAIAQEKLWLDKNYQWTDDSIQAVKYALVS
                     KINKKCIKVEEYALEGQKKDVWHFSEYKSNPRKRIREGLHTSFYANGKDSLTEVYRDNR
                     LEGQTMVYYPDGAIHLARSYSDGKLDGTLLQYYPDGKLRREEHYSENQCTGGKMFDEHG
                     TEMEHQPYFVFPSFPGGIENLMKLVANVTKYPEDAWKQKAEGRVILXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYDIDKEAIRAFEAIADVYRWSPGYQDGE
                     AKRVKFTIPLYFRIPK"
     CDS             complement(8851..9870)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 137.3;
                     E-value: 1.8e-42)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg167_9"
                     /sec_met_domain="ETF (E-value: 3.2e-43, bitscore: 137.3,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 1.3e-38, bitscore:
                     120.6, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNVFVYLEIEGTTVADVSLELLTKGRKLANQLGCQLEAVAAGNN
                     LAGIEKQVLPFGVDKLHVFDAPGLFPYTSLPHSSVLINLFKEEKPQICLMGATVIGRDL
                     GPRVSSALTSGLTADCTSLEIGNHEDKKEGKVYENLLYQIRPAFGGNIVATIVNPEHRP
                     QMATVREGVMKKEILDADYKGEVINHDVAKYVPETDYVVKVIDRHVEKAKHNLKGAPIV
                     IAGGYGMGSKEGFDMLFELAKELHAEVGASRAAVDAGYADHDRQIGQTGVTVRPKLYIA
                     CGISGQIQHIAGMQESGIIISINNDENAPINTIADYVINGTVEEVIPKMIKYYKSHSK"
     CDS             complement(9875..10942)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 100.7;
                     E-value: 3.1e-31)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg167_10"
                     /sec_met_domain="ETF (E-value: 5.5e-32, bitscore: 100.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLKIVVLAKQVPDTRNVGKDAMKADGTINRAALPAIFNPEDLNA
                     LEQALRLKDEHPGSTVTILTMGPGRAAEVIREGLYRGADNGYLLTDRAFAGADTLATSY
                     ALATAIKKIGDYDVIIGGRQAIDGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXGVETVEAPLPIVITVNGSAAPCRPRNAKLVQKYKRALGAQEKAAITKEGAELA
                     YAGLYEKYPYLNITEWSVADVNGDLAQCGLSGSPTKVKTIQNISFQAKESKTLTGSDKD
                     VEDLIVELLANHTIG"
ORIGIN
        1 gttttccctg attgcttaat caaataggag aaccgcagtg tctttttgat agatactgcg
       61 gtttttttgt tctatttacc ttcttgatta ttaataaaaa gcgtgtaata ttacaaaagt
      121 gttacaaaaa tgattagttt tcatatcttt tgttcgtttt tgttgttagc aaaataaaaa
      181 atcatatctt tacccttcgt aaagataacc taatcaacaa gaactattaa cctttttaat
      241 tgaagagaaa atgaacaaaa gcgaaattgg actaaatgct gggaaagttt ggcagttgct
      301 tagcgattat accagatgga gctacggttc tttaaagagg aagtccggac tgaaggacaa
      361 ggagttggga gccgcattgg ggtggcttgc ccgtgaggac aagattgaaa ttcatcagga
      421 agaagatgaa ctttatgttt cactaggggt aaatgtttat atcggataaa gggaaccgag
      481 tgaatggatt gattgagggg cacagatttc atagtgcgga agcattttct gccgggggga
      541 tgaaatctgt gctcctttgt tttttcatgt tgcagaatat tctttccttt gcacattctt
      601 ttcaatgaac aaaaacagaa agattatgag aagttttgct tcagacaata attcaggcgt
      661 acatccgttg gtaatggagg cactgaaccg ggccaacagt gaccatgctg tcggttatgg
      721 ggatgaccct tggacagaag aggctgtccg taaaataagg gaagcgttta cgccggattg
      781 cgaaccgttg ttcgtattca atggtacggg cagtaatgcg gtggctttgc agctgtgtac
      841 ccgcccttat aattccatta tttgtgcgga gaccgcacat atctatgtcg atgagtgcgg
      901 tgcgcctgcc cgtatgacag gttgtcagat tcgtcctata gctacccctg acggcaagct
      961 gacgcccgat ttagtccgtc cttatttgtg ccatttcggc gaacagcatc attcgcagcc
     1021 cggagccatc tatatttcgc aatgttcgga gctgggcact gtctataagc cggacgagtt
     1081 gcgggctttg acggatttgg cccatcggca tggcatgtat atatggacgg agcacgtctg
     1141 gcaaatgctt gtgcagcctt gaatcttggc tttagggaac tgacagtgga ttgcgggata
     1201 gatatcctca gcttcggtgg tacgaaaaat ggactgatgt tgggagaaag cgtggttgtc
     1261 tttaacccag ctttgaagaa ggaagcttat tttgtgcgca agcagtcggc acagctcgca
     1321 tccaagctcc gctatctgtc ctgccagttt actgcctatc tgacggacag cctttggttg
     1381 aaaaatgccg cgcatgccaa tcgtatggca aagattcttt acgacggatt gaaggaattg
     1441 ccaggtgcgc attttacgca gaaggtggaa agtaaccagc ttttccttac gatgccccgt
     1501 ccggtgattg acgagctgtt gaaggactat ttcttctact tctgggatga ggccatccac
     1561 gaaatccgtt ttgtaacctc ttttgatact acggaagaag atatcgagca attgctgcaa
     1621 tcggtaaaaa ggcttctctg aaatatataa aagctcctaa ccttcacagg ctgggagctt
     1681 acttcgaaac tttcccctct tgggggtagg ggaaggttta ctgaaaacaa accgattgaa
     1741 tatttacctt aaataccttt gcacgataac ctttttaact aaccttttca ataaatcttt
     1801 gttagagtat gcttatatac cgacagcctc gcggaccggt acaaaagtgt agccttttcg
     1861 tttcagcgtc ttaatcatct tgtccagata gccattatag aacttgtctg tgcggcggtc
     1921 gtccgttccg aagtgtatca gcattaggtg tccgttcaga ccttctttct tttccacctc
     1981 cataatcttg tcgtagatga atttgctgct ccggtacttc tgtcccatgt ccggagtggt
     2041 gtagtcggca ttgctcatgg taccaggggt atagttgatg acttgaatac ccatattctt
     2101 tgcccaggca gatatttcct tgttatagta ttcgtaagga ggaatataga cgggagcgtc
     2161 cttgtattcg atacctgcct tgcggagggt ctcgtagctt ttcatcatat cgttctcaaa
     2221 ctcttcgcgg gtgaccagca gagaatcacg gtcttcccaa ggcatgtaca acagatgtcc
     2281 gtaactgtgg ctgcctacaa aatgcccttc gtcgagcagg cgtttcacta catcgggata
     2341 gagttcatag aactctccgg taaagaagaa gccacctttg atgccatgct tcttcaaggt
     2401 actgatgatg gcatcggcac cgtctgcttt gtcggcggca gtgaatacga gggtgatttg
     2461 cttttttgag ggatcggtgc ggataatgcc tccgtccaca tatacattct tgtcatttgg
     2521 gataccggct tgcttcattc catccttctg catggcagag aggtagtacg tgaggcaggc
     2581 ggttccatcc atggtaggct cattggtgga atagtcgtgg atggcgtcgt gatataccat
     2641 caggtctggc tggaagcgtt cgtagtcttg tccgggagtt ccgggaattc ccgtcatatt
     2701 gacaccgcgc aggctttcga agatggtacg atagacagga ccgtccacca gtccgccggt
     2761 agtattgccc acgcctgcat tcagcagtga ggagtggggt tgcgagggat agtctccgta
     2821 aaggggaagt tccacaatca tgctggttcc ccaagggtta cagccgaaca gccagtcgcg
     2881 cagggaggct tccatttcgg cgtatgtgtc atcgccggtg gtttcacggt acagccggca
     2941 ttgggttagc atggcggtag tcagattgtt ggaacaccag atgtagggta taccgtgcag
     3001 gaaggggctt tctaccgctt tctcgtacgt gcgttcaatg cccgtacgca tgttgcggat
     3061 gaattccttg ctgatgcggc tgttgtccac tttggcaaga tggtagtgcc ccatgttcat
     3121 gaacggatac cattggtagt ggcgtgcact gtcggcgccc atccaaggag tcaccggttc
     3181 gcgacgtccg tattcaaggg cttgggccag gtatttgttg tcgccggtgg ctttgtacag
     3241 ttccatggct cccagttcca tatcgtccac ccagttgtcc tcttcgtaaa tgtagggaga
     3301 caagacagag gcagtctggc atgctcccgg tttctttacg ccttcctgat aggcggcatc
     3361 ggccttggct tcgatttctg ctgcaaattc aggatagtag tctttcagta tcttggcgcc
     3421 taaagcgaag caggaggcaa acttgccggc agtgcttgcc actccggtcg ttgcattctt
     3481 gaactctcca cgtacttgcg gttcgccact gcaaaagtaa acggggcgtc ctttacccgg
     3541 tccgtagccg taatccacca ggtctttgtt aggtaggcgc attccggcat ggtcacggtc
     3601 gtcggctatc tggttgtaca gctcgcccgg agcaggattc atccggttca gccagtccag
     3661 tccccacttg atttcgtcca cgatgtcggg aatgccgttg gctcccggat gtccggctgc
     3721 atcataggcg tcaccgaatg attccggatt ttcctgatag gcaaacatca tctggtagat
     3781 ggcattggcg gaggtggtgg tgtattgcag atagtccgta gcatcgtgcc agcctccgcg
     3841 gacgtctata tgttgtccgg ttttggtggg atgatagacg atgtagccgt cgtgcacgtg
     3901 gcagctgtct ttcaggaacg gattatagcc gcagcgttgc tgccgcatgt agtgcagcag
     3961 gtagtctgcg gtaccgttgt agacttgtgc attgatgggg aaacgggggg agaccgcttt
     4021 gcctgctttc agataatacg tgcccggttc tgtgaaatca ctgaagttca accggtaggt
     4081 actcttcatg cctcccatct tgccggtggc cttggttgtg ttgaaggtac gcaccacctt
     4141 tccggtgaaa gcgtcaatca atgaataatt ttctacgttt gttccttcct cgctcatgaa
     4201 tacagcgact ttgacggatt gcggcaaata gccgagttgg ttgattctga tccattcgcc
     4261 tgctttgccc ggcagggcta cgagagcgaa tattaccgtt aggagccaat aattactttt
     4321 cataatgggg gtttttaatc taaggttggg gattatatat aaaacaaatt ttccttatta
     4381 caaataaagc attttctgtc aattttagga agatttagga tgaataatta gacgatatta
     4441 ggtgtcgttt acactatttt ggtattttat agacgtgaaa taagtgtttg gttgaaacta
     4501 aatgtttgtt tatcacgtaa ttattatgct tgatgatgct ttttaatttt cgtttaccta
     4561 ttttagtaat gcgtaaaaca aattggcgtg ttatttgttt tatggtattt agacaataaa
     4621 actaatagac tatggcttat attgattact atcaggtcct tggagtggac aaaaaggcat
     4681 ctcaggatga catcaagaga gcgttccgca agctggcgcg caagtaccat cctgacttga
     4741 atccgaacga tgctacggcc aaggataagt ttcaggctat caacgaggcg aatgaggtgc
     4801 tgagtgatcc tgaaaaaaga aagaaatatg atgaatatgg tgaacactgg aaacatgccg
     4861 acgagtttga agcgcagaag cgggcacagc agcaagccgg gggcttcggg ggatttggcg
     4921 gtgccggttt tggaggttcc ggtgcgggat ttggtacgga cggaggcggt acgtattggt
     4981 attcttccga cggccaggaa ttttcgggca gtaatgccgg tggtttctca gacttcttcg
     5041 aacagatgtt cggtcatcgt acgcgcggcg gaggtggtgc caatgccggt ttccgcgggc
     5101 aggattatca tgcggatttg aacctctcgc ttcgtgaggc tgcgaagacc cataaacaga
     5161 tattgacggt gaatggcaag caagtgcgta ttaccattcc ggccggtgtg gccaacggac
     5221 aggtcatcaa actgaaaggc tatggtggcg agggcatcaa cggaggtcct gcaggtgact
     5281 tatacatcac gtttgtgatt ccggacgact cggtattcaa gcgtttggga gatgatttgt
     5341 atgtggatgt gaccgtcgac ctttatacag ccctgctggg tggcgaccag ttggtggata
     5401 ctttggatgg tcaggtgaag ctgaaggtga aacccgaaac tcagaacggg actaaggtac
     5461 gtctgaaggg taagggcttc cccgtatata agaaggaggg acagtttggc gatctcatcg
     5521 tgacttattc cgtgaagttg ccgacaaacc tgacggaaca gcagaaagag atgttccgta
     5581 aaattcagag tatgaactaa tgaaaggaga acggattatg cagaacgaat ggattgtcat
     5641 cagcgaatat tgtgacaagt gtcatataga gcccactttt attgatatgc tgtgcgaaag
     5701 tggactgata gatgtggagc aggaaggtgg agagcgttat ctgcctttct ccgagttgcc
     5761 ggatgtggaa cggtacagcc gtatgtacta cgacctttcc atcaatatgg aagggattga
     5821 tgccatccac catctgctgg caaggatgga agagatgcag cgggagatac actcgctgcg
     5881 cggcaggctg aggctgcacg gagagtatta attttccttt cgtctctttg agaacttttg
     5941 tccttttaag aaggggcaag caggaggaag tatttcagaa aaaacaagcg ggcaccggag
     6001 tagctaaact ccggtgcccg ctatatttgc cttgtccaag caatgcgttt atttgcggta
     6061 gctttccagc tcttctgcct tgaacttacg gatgaagtta aagtgttttt ccacttcagc
     6121 ttctgcgtag ttcacataca ccagagccga cttgccgaac agttcgggag cctttgtcgc
     6181 gtcctggatg atgaggtgcg acatgataca taccgcagcc atctcataga ggcgacgtgc
     6241 cacgaagtcc agcaattctt gattctgtgc ctctttcacc gcattggtgc aggcttcgaa
     6301 cttgttggtc atctctttga tgcggtccat caacggttgc atttcttcgc tgcacggcac
     6361 ttgctcgtag tcgcgcaagg tggcagagta tgagccgttt gttacatagc ggatagcagc
     6421 tacggtctgc aactgagtag taccttcgta gatagaagtg atacgtgcat cacgatagat
     6481 acgttggcaa gcatactcca gcatgaagcc cgaaccgccg tgaatctgga tgctgtcgta
     6541 agcattctga ttggcatatt cagagttcat accttttgcc agcggagtga aggcgtcggc
     6601 aagtttggca tacttctttt gttcctggcg ttcttccgga gtcagtttgc gttcgcgagc
     6661 aatgtcgtcc agcgctttgt agatgtccac gtagcgggaa gtctggtaca gcaaggagcg
     6721 tcctgcatcc aacttggctt tcataatagc cagcatgtca tatacagccg ggaattcgat
     6781 gatagccttg ccgaactgct tgcggtcttt ggcataagcc agaccttcgt tgtaggcagc
     6841 ttgtgaaagg cctaccgact gtgcggcaat acccagacgg gcaccgttca tcaaagccat
     6901 aacgtattta atcaaaccaa gcttgcggtc gccgcaaagt tctgcctttg cattcttgta
     6961 aaccagctcg caggtgggag agccgtggat acccagcttg ttctcgatgc ggcgcacgtc
     7021 tacaccgcct tcattcttat cgtagatgaa catggacaag ccacgtccgt ctttggtacc
     7081 ctcttctgaa cgtgccagta cgaggtggag attggcgtca ccgttagtaa taaaacgctt
     7141 cacgccgttc aggcgccagc agttgttggc ctcgtcatag gtcgctttca gcattacgct
     7201 ctgcaagtcg gaaccggcat ccggttctgt caggtccata gacatggtct ctccggcgca
     7261 gacacgcggt ataaaacggc tgtgctggtc ttcgttaccg aattcgtaga gcgtttcgat
     7321 acagtcttgc agtgaccaga tgttaccgaa accggcatcg gcggcggcaa cgatttcggc
     7381 acacatggtg tacggagtaa tcgggaagtt caagccaccg aaacggcgcg gcatggtcat
     7441 accgttcaat ccggctttta ccatggcgtc gaggttctgc ttggtgccgc tggcatattc
     7501 cacacggccg ttggcacagt ggggaccttc ttcgtccacg ccctcggcat tgggagcgat
     7561 aatctctccg gtaatctctc cggtgatttc aagtaccttg tcaaaagagt ccatagcatc
     7621 cgcatagtcc tgcggggcat agtcatactt gtctttgtct tggtaaccgc gttctttcag
     7681 ttcgcagata cgttccatca tcgagttgtt cagatgatac ttcaattcgg gaacttcggt
     7741 ataaaaattt gccataattt cttggttatt taggtattct gaagtatagg ggtatggtga
     7801 atttcactcg cttggcctct ccgtcctgat agccgggcga ccagcggtag acgtcggcaa
     7861 tggcctcgaa agcgcgtatg gcttctttgt cgatgtcata nnnnnnnnnn nnnnnnnnnn
     7921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngc aggattaccc
     8221 ttccttctgc cttttgcttc caggcgtctt ccggatattt ggtaacattg gccaccagtt
     8281 tcatgaggtt ctctattcca ccggggaagg atggaaacac gaaatacggc tgatgttcca
     8341 tttcagttcc gtgctcgtcg aacatctttc caccggtaca ctgattctct gaatagtgtt
     8401 cctctctacg gagtttcccg tcgggatagt actgcaggag tgttccgtca agtttaccat
     8461 cgctgtagct ccgggccaga tgtatggcac cgtcgggata atacaccatg gtctgcccct
     8521 ccaggcggtt gtctctatat acttctgtca ggctgtcctt gccatttgca tagaatgatg
     8581 tatgcaggcc ttcccttatc cttttgcggg gattgctttt gtattcggag aaatgccaga
     8641 catccttctt ttgtccttcc aaagcatact cttccacctt gatgcacttc ttgtttatct
     8701 tggaaacaag agcatacttg actgcctgga tggagtcgtc cgtccattgg taattcttgt
     8761 ccaaccagag cttttcttga gcgatagcgg aagatatacc tgaaagaaga acaaatataa
     8821 gaatcagccc tttcatgatt acctttattg ttatttactg tgtgatttat aatattttat
     8881 catcttcggg ataacctctt ccaccgtacc gttgatgaca tagtcggcaa tcgtattgat
     8941 gggagcgttc tcgtcattgt tgatggagat gataatacca ctttcctgca taccggcaat
     9001 gtgctggatt tgtccgctga tgccgcaagc aatatacagt ttggggcgga cagtgacacc
     9061 ggtctggcca atctggcggt catggtcggc ataaccggca tcgacggcag cacggctggc
     9121 gcctacctct gcatggagtt ctttggcaag ctcgaacaac atgtcaaaac cttccttgct
     9181 tcccatgccg tagccgccgg caatcacgat gggagcgcct ttcaggttgt gttttgcctt
     9241 ttctacgtgg cggtcgatga cttttaccac ataatccgtc tcgggcacgt acttggcaac
     9301 gtcgtggttg atgacttcgc ccttatagtc agcgtccagt atctctttct tcatcacgcc
     9361 ttcgcgaacg gttgccatct gcggacggtg ctcgggattc acaatcgtgg caacgatgtt
     9421 accgccgaat gcgggacgga tttgatacag caggttctcg taaaccttgc cttccttctt
     9481 gtcttcgtgg ttgccgattt ccagtgaggt acagtcggca gtcagtccgc tggtcaaagc
     9541 ggaagaaacg cgcgggccga ggtcgcgacc gataacggtg gcgcccatca ggcagatttg
     9601 cggcttttct tctttgaaca aattgatgag gacagaggag tggggaaggg aagtataggg
     9661 gaacaagccc ggagcgtcga atacgtggag tttgtctact ccgaagggca atacttgttt
     9721 ttcaatgcct gccagattgt tgccggcagc aactgcctcc agttgacagc ccaactgatt
     9781 ggctaattta cgacctttgg tcaagagttc gagactgacg tcggcaactg ttgtgccttc
     9841 tatctctaaa tatacaaata cattattcat aatcttatcc tatcgtatgg ttagctaaca
     9901 gttcaacaat caaatcttcc acatccttgt cgctgcccgt cagcgttttg ctttctttgg
     9961 cctggaatga gatgttctga atggtcttca ccttggtagg cgaaccgctc agaccgcatt
    10021 gtgcaaggtc gccgttcacg tcggcaacac tccattccgt gatgttcaga tagggatatt
    10081 tctcgtagag gccggcgtag gcaagctcag cgccttcctt ggtgatggca gctttttcct
    10141 gggcaccgag ggcgcgtttg tacttctgca ccagtttggc attgcgcggg cggcagggag
    10201 cggcacttcc gtttacggtg atgactatgg gcaggggagc ctcaacggtt tccacaccnn
    10261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc
    10561 cgtcgatggc ctggcgtccg ccaatgatga cgtcatagtc gcctatcttc ttgatggctg
    10621 tggcaagggc atacgaagtg gcaagcgtat cggcacctgc aaaggcgcgg tcggtcagca
    10681 gatagccgtt gtcggcacca cggtaaagtc cttcacgaat aacttcggct gcacgtcccg
    10741 gtcccatggt caggatggta acggtggagc ccggatgttc atctttcagt cggagagcct
    10801 gttcaagagc gttcaggtcc tcggggttga agatggcagg gagtgccgcg cggttgatag
    10861 ttccgtcggc tttcatggca tctttcccaa cgttgcgtgt gtcgggaact tgttttgcca
    10921 atacaacaat tttcaaactc atgctattaa ttattagtat tagtatttct ttgtatgtca
    10981 gtaccgggaa taggagtagt agaatcctgc tactgaaatt ggccggttaa ctcattatca
    11041 gcctgcaaat ttacggaaag agttgggttt gacaagaaaa tggggtgaaa aatgcacaag
    11101 ttgagggatt ttgcgcaaat atcagttggc tctatatctg taaaaaaggt aataaaaccg
    11161 gtaatttatc tacctttccg ttcccgtttc ctctgtactt ttgcagcgtc cggatgaggc
    11221 ctgcacgacg ggcggcatcg gataaacaag catcgctact taaatgttat tatagaatat
    11281 gtatattgaa aaagtaaatt cccctgctga cgtgaaaaag ttatcagtca gcgagatgaa
    11341 cggattaggt ggagaaatcc gccaggtgtt gttaaacaag ttaagctctc acggaggaca
    11401 cgtaggtccc aacctgggaa tggtagaagc caccatagcc ctgcattacg tgttcgattc
    11461 accaacggac aagatagtct atgacgtgtc tcaccaaagt tatacccata agatattgac
    11521 aggccgccgg gcagcgttta tgaatgcgga cgagtatgac gaagtctccg gatattccga
    11581 accgtcggaa agtgagcatg actttttcgt cattgggcat acctctacct ccgtcagtct
    11641 g
//
