LOCUS       c00050_gnlPro..        22414 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDIBMNHB_50.
ACCESSION   c00050_gnlPro..
VERSION     c00050_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:47:12
            Original ID  :: gnl|Prokka|HDIBMNHB_50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22414
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..420
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ILVD_EDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_1"
                     /sec_met_domain="ILVD_EDD (E-value: 1.3e-43, bitscore:
                     140.5, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVIRYEGPKGSGMPEMFYTTEAIASDPELVETIALITDGRFSGAT
                     RGPAIGHVSPEASEGGPIALVENDDLIRIDIPARTLDIIGTDSIERSVEEIEKILSERR
                     AHWIKPESQYKKGILDIYTHNSVSPMKGAYMEFFM"
     protocluster    1..22414
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6981:12414]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6982..12414
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..22414
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22414
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             446..1474
                     /locus_tag="ctg50_2"
                     /transl_table=11
                     /translation="MRKNISILVSLLILSHTACSDKGQYFEESGSVFHTSYHIKYKAKQ
                     ILTDKIDSELQRFNLSLNPFNPNSTIAKVNNNEDVEVDEWFTEVFNKAEEISQKSGGAF
                     DITCAPLINLWGFGFSKMDSVTPQMIDSIKAFVGYQKVRLEGKKIIKEDPRILLNCSSI
                     AKGYACDVIARLLEKEGVKNYMVEIGGEVTMKGVNQQGDCWRVGINKPEIGTSGVTNDV
                     EEIVQLCQKGGVATSGDYRNFYIKDGKKYAHTINPATGYPAGQNILSATIVAEDCMTAD
                     AYATTFMVLGVEKAKLLAQSIPQIEYFIIYADNNGQQKVTYSKGMLEYLPNRKTLAILE
                     NP"
     CDS             1483..1860
                     /locus_tag="ctg50_3"
                     /transl_table=11
                     /translation="MKRYLNQLECKILRAGDSLFNTTTTDNLLIFVFSGKLIIYSQEGT
                     HIAEVAKDHFMLLAQNTNHKVIASAPTRLILIHAGSLSDMIINDPEWNVEKPVVLPIPP
                     ALAHTLNQIEYYMKDKYFTLN"
     CDS             complement(1863..2444)
                     /locus_tag="ctg50_4"
                     /transl_table=11
                     /translation="MLENLKKYKIVLASNSPRRRNLLSGLDIDFEVRVIPDIDESYPDS
                     IDSMEIPLYIARSKAEAYKSTMADDELLITADTIVWTFDGVMGKPANREEAYAMLHALS
                     DHVHQVITGVCIMTKDKNVGFSVESAVCFAKLGDEEINYYLDKYKPYDKAGGYGIQEWI
                     GYIGVEAINGSFYNVMGLPVQKLYQELKHF"
     CDS             complement(2482..3003)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_5"
                     /sec_met_domain="HAD_2 (E-value: 2.5e-08, bitscore: 25.4,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSINYDLRKIKAFVFDVDGVLSCDVIPLHPNGDPMRTVNIKDGY
                     ALQLAVKKGYEVAIITGGYTEAVQIRFSRLGIQHIYMRSAVKVHDFKDFMEKTGLSPEH
                     IMYAGDDIPDYEVMTRVGLPVAPADAAPEIKEIAKYISSRRGGEGVARDVIEQTMRAQG
                     HWFGEEAFGW"
     CDS             complement(2996..3763)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_6"
                     /sec_met_domain="F420_oxidored (E-value: 3.1e-09, bitscore:
                     28.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVFVGAGNLATRLSLEMRKSGMSIGQVYSHTSEHAKILADELG
                     CGWTVIPEEIVEDADLYVFSLKDAVLQDVIARVKPNNGLWVHTAGSMPISVFEGLTARY
                     GVVYPLQTFSKSREVDFKKIPFFLEANSSEDETVLGEVARALSSDVRFLSSEKRKNLHL
                     AAVFACNFTNHMYALAEKILEEQQIPGEVLLPLIDETAAKVHVMSPAQAQTGPAIRYDE
                     NVINKHMAMLKDPGMRNLYELISRSIHKEARHE"
     CDS             complement(3760..4230)
                     /locus_tag="ctg50_7"
                     /transl_table=11
                     /translation="LKAALMAPASKRSNPWQFVVVEDKEMLKKLAGCKKNGSAFLEGCA
                     LAVVVLANVMESDVWIEDASVASIYMQLQAEDLGLGSCWCQIRNRVTEDEVDSNNYVRS
                     LLDIPYQLDVLSIIGIGYKDQVRKPFDESHLQWEKIHIGKFSLPEENKETGE"
     CDS             4442..6853
                     /locus_tag="ctg50_8"
                     /transl_table=11
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVRV
                     KNTLIGSMTNEKGYYSFSISPGDSISVIYSCLGYNKAERIIPSAQADMRLNVQMNNTSF
                     DLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQYSVR
                     GGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSV
                     LDITYKKPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTDAEYDP
                     KFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVYFDGRER
                     DRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAENPDDDASA
                     AMSVGRYHEHARNRLNSTVMNVGHYGMARLLNNTLKWGATVQMEKINDKISEWEKRDSS
                     GYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVAGVRGSYWTYN
                     KEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRRVDKDKNGNNITVLNKDLK
                     SQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRYYGENCAKGYAM
                     GLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISLFFQDYFPGYKRV
                     KLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGTDAIMDRGFFRHLK
                     NIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVRLIVDF"
     CDS             6982..7392
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_9"
                     /sec_met_domain="Glyoxalase_4 (E-value: 8.3e-27, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             7429..7803
                     /locus_tag="ctg50_10"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXYRHVA"
     CDS             8373..9887
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_11"
                     /sec_met_domain="CT_Btheta (E-value: 3.5e-85, bitscore:
                     277.6, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLFLRFPVSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTTKSGVAHFAVDTEEDGLQL
                     IRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNANQSYDMYEVIGTIVDNNEF
                     LEVHADYAKNIIVGFARFNGQSVGIVANQPXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITVTLRKSYGGAYCVM
                     SSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAAEKEAEYKKAFANP
                     YNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL"
     CDS             9903..10796
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_12"
                     /sec_met_domain="OAD_gamma (E-value: 8.8e-13, bitscore:
                     40.1, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMINKKIGVLLLFALLISFGAKAQRATSMRINEVLVINEDNFVD
                     DYGKRHGWIELFNTSAGTVNIAGCYLTDDKNNPMKYPIPKGDVLTQIQPRQHTLFWADG
                     QPGRGTFHVNFVLDPSKENYIALYDADGKTLIDEVTIPAGQMADISYGRVIDGKDEWAQ
                     LKKVTPSTNNLTLDSNEKIDNFKQNDSLGIGMTITAMAVVFLGLFLLYIIFKQIGRLSI
                     SASKRNAQKAAGTTSVSVDAGQESGEIFAAIATALYEMSDDNHDIEHTVLTIHKVQRTY
                     SPWSSKLYGLRQTPHK"
     CDS             10818..11249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 64.8; E-value:
                     1.6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_13"
                     /sec_met_domain="Biotin_lipoyl (E-value: 9.5e-21, bitscore:
                     64.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIADVEVNGTPYQVKLEKPAKKQ
                     MVTLKRPAQAPTTASGDPVVTRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTLII
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             11254..12414
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_14"
                     /sec_met_domain="OAD_beta (E-value: 2.8e-153, bitscore:
                     501.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLTFLGENLQLFLTYTGVYNATPGHLIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYTIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKLFNLILKDGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(12481..12627)
                     /locus_tag="ctg50_15"
                     /transl_table=11
                     /translation="MRKKSVNTLLVFGVVVAIILLMIWLFLGTTLVEDTSTEITPVSIE
                     QTN"
     CDS             complement(12696..13412)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_16"
                     /sec_met_domain="Peptidase_M22 (E-value: 6.6e-28, bitscore:
                     89.4, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLILNIETSTSVCSVALSEGEEVVFEKASFEGPSHAALLGVYME
                     EALEAAKSKGMKLDAVAVSSGPGSYTGLRIGVSVAKGLCFGYGIPLIGIHTLDILASAA
                     IRKNKEEADCLYCAMLDARRMEVYSSIYDSHLNTIRATTADIVDADSYASFLENGKVCF
                     FGDGAAKCETVITSPNACFIAGIYPLAVNMASLSQKAYDDGRFENVAYFEPFYLKEFQA
                     TIAKNKVLNEALGKNK"
     CDS             13614..14474
                     /locus_tag="ctg50_17"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKDKEMEL
                     RSLLLQSLERGKVEFNIFIEYIGKDTPTQINLAAVENYYNQIKEIAEKLNISVPNDWFQ
                     TLLRMPDAIKSETVEPDESEWGVVLETVKDAIKHLCDFRIQEGAMLQKLFEQKIANIAT
                     LLKEVEKYEGERIEKIKARIMDNLQKIAEKDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYFISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMKDELEQIKEQ
                     VLNVL"
     CDS             14489..15055
                     /locus_tag="ctg50_18"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINYLLKQDLHLRFSISATSRAPRGTE
                     KNGVEYYFLTPEEFRSRIANGDFLEYEEVYTDKYYGTLKSEVERILNEGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPCIDDLRKRLEGRGTDSPEVIESRIAKAEYELGFTGQFD
                     KVVVNDDLETAQKDALKIIREFLNK"
     CDS             15059..15238
                     /locus_tag="ctg50_19"
                     /transl_table=11
                     /translation="MSNIFKNTRFMMGLSIVCGIASLVLGGISLYYKEYIIGGALIFNI
                     FICFINYKGWQKKG"
     CDS             15250..15825
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_20"
                     /sec_met_domain="CTP_transf_like (E-value: 2.9e-24,
                     bitscore: 77.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLKTGIYSGSFNPIHIGHLALANWLCEFEGLDEVWFVVTPHNPL
                     KKKDDLLDDSLRLEMAQAAIDGYPKFRVCDIEFYLPKPSYSIDTLRTLSRNYPNRDFYF
                     IMGADNWQLFPRWKEHEKILQDYKLLIYPRLGFDISIPAIYPNVKKVDAPLMEISSTFI
                     RNAYQTGKDIRFFLPEGVRPYFGSVANQ"
     CDS             16744..17859
                     /locus_tag="ctg50_21"
                     /transl_table=11
                     /translation="MIYLLFLVTLLLISCNPDQAKDNGKDETIEYFIPLSHRVEKDVDE
                     MFEEYRYVPLETRDDALIDVLYNVKNIAIFQEDIYIGSGEQLIVWDKYGKFKRVLSKKG
                     NDPQSYLHFNHFMIWPNGDLSIASPIEIVTYSNSHQFINKKRCENVGYIEAITLLNDSL
                     YIIKCMPTPEQLRYRIINHHTGAIINSYDSIINCNRYISSFTNSFERYEGHIISHGYQS
                     NDILECTLDSSKIRYKINVDNRIPPAGFYTQEGKEGMQLIQEEAEKGYIGHIPDYVESK
                     ETILLSFKGKREDLNGIALIDKKDGNARVLENIKFDDNFRWLPKQFFSLDEGWCAMLMY
                     PEDVLKKEEFARRFPGLDEESNPVLFIGKLR"
     CDS             18359..19426
                     /locus_tag="ctg50_22"
                     /transl_table=11
                     /translation="MEIGIWGLWGVNVIGASFCGILLSREILGSDKYVNKICSLFLKSS
                     DCNGTLDSQASHFLGISWSVFGLGYFLSAILFIALLPQYVIYAETLNIIALPYTAWSVW
                     YQKFRVKQWCALCLSVQATVWITFLISLFAIGMDFNQWDLFDFTTIGCVYGLVILSLHF
                     TVTLYVKEKQIQRSNNKLSSIKLNASVFKSLLNEQPQYDIDKNTGILLGNRDAKEWITI
                     ISNPHCAPCAKLHLQIEKLLKEYKEEICIQIILTSFSKELEPSAMLLTSMYLLNNESDY
                     LRFLSDWYAKGRHKKEDCYKRYRLNPNDKDMLANFQAQNEWVRRNTISSTPTVLTNGYL
                     LPEEYELKDMSYLIN"
     CDS             19510..20475
                     /locus_tag="ctg50_23"
                     /transl_table=11
                     /translation="LAHGKMGLLIYLYHLYDYTQEAIYKEKAERLLDDLLENDLSKNAE
                     LTVEEGLCGVALGLDYIVKKQFVDGDINDLLSGIDDLLFKKLVFGNMESRYSLSQLIHF
                     LYYIYKRLEIQTNDNERFPFEGLAIKLVNQLADLIDASFFEESYTFSIYQYHVPILMKT
                     LSCLIQYDFYKDRIQKVLEQLSLYMFSHLPHLHLNRLYLLWGILPLRNCSPDWQRYVNE
                     LRKSINLDIIYNREIKGKDIYISNGYASLYFLLEGLKRDFPEYTIPFNPHLIYDRIISS
                     DAWDALMENEYYYNIHRGLLNGFPGTVLALLNIKQRYLCE"
     CDS             20466..21155
                     /locus_tag="ctg50_24"
                     /transl_table=11
                     /translation="MRIDLTDTTFIIPVRIDSMIRLENLLMSVDSIVRYFRTRILIMEA
                     SSYQNEIIPSLIKDDTVKYTFLVDKDPVFYKTKYLNILAKQVDTPLVCIWDADVILDHL
                     QILDAVKQLRTRTSDVAYPYDGNFLDTSDILREHYWLHRDLDFLKKHQAKMNSLYTVEG
                     VIGAVGGAVFAQTEKYLQAGMENEDFYGWGLEDGERHYRWLSFGYRIYRSEGCLFHLSH
                     PRDQNGM"
ORIGIN
        1 gttgttatcc gttatgaagg accgaaagga agtggaatgc cagaaatgtt ttatacgaca
       61 gaagcgatcg cctccgatcc tgagttggta gagaccatcg cattgatcac cgacggtcgt
      121 ttctccggag cgacccgagg cccggcgatc ggacatgtat ccccggaggc ttccgagggg
      181 ggaccaatcg ccttggtcga aaacgatgac ttgatccgta tcgatattcc agcgagaaca
      241 ttggatataa tcggtaccga cagtattgag agaagcgtgg aagagataga aaagatccta
      301 tccgaaaggc gtgcacattg gataaaacca gagtcacaat ataaaaaagg aatccttgat
      361 atttatacac acaatagcgt ctcccccatg aaaggggcat atatggaatt ttttatgtaa
      421 gttcgcgaca taaaatttca taatgatgcg caagaatatt tccatattag tcagcctgtt
      481 gatcttatcg catacggctt gctcggacaa gggccaatat ttcgaagaga gtggttctgt
      541 ttttcataca agttaccaca tcaaatacaa ggccaagcaa atcctaaccg ataagatcga
      601 cagcgagctg caacgtttta acctctcctt aaatcctttc aaccccaact ccacgatcgc
      661 gaaagtcaat aataacgagg atgtggaggt agacgaatgg tttaccgaag tattcaataa
      721 ggcggaagaa atctcccaaa aatcaggagg agcttttgat attacttgtg ctccattaat
      781 taatctatgg ggattcggat tcagtaagat ggatagcgta accccgcaga tgatcgatag
      841 cataaaggct ttcgtcggtt atcaaaaagt gagattggaa ggaaagaaaa tcatcaaaga
      901 agatccccgg attctattga attgttcgtc catcgcaaaa ggttatgctt gcgatgtcat
      961 cgcccgcctg ctggaaaagg aaggcgtaaa gaactacatg gtagaaatag gtggtgaggt
     1021 caccatgaaa ggcgtaaatc aacaaggaga ctgttggcga gtcggcatca acaagccgga
     1081 aatagggaca agcggcgtaa caaatgatgt tgaagagatc gtacaattat gccaaaaagg
     1141 aggtgtggct acttctggtg actaccgaaa cttctacatc aaggatggta agaaatatgc
     1201 ccatacgatc aatccggcga ccggttatcc cgctggacaa aatattctta gcgcgacaat
     1261 cgtggcggaa gattgtatga cagcagacgc ttacgctacg actttcatgg ttttgggagt
     1321 cgagaaagcg aagctactgg cacaatccat cccccaaata gagtatttca ttatttatgc
     1381 ggacaacaac ggacaacaga aagtcaccta ctcaaaaggt atgttggaat accttcctaa
     1441 cagaaaaaca ttggctatcc tcgaaaatcc ttaagttcct acatgaagcg ttatctaaat
     1501 caacttgaat gcaaaatact gagagccgga gattccctgt ttaataccac aaccacggat
     1561 aacctattaa tcttcgtatt ttcgggaaaa cttattattt acagccaaga agggacacat
     1621 atagcggaag tggcaaaaga tcatttcatg ctacttgcgc aaaacaccaa tcataaggtt
     1681 atagcctcag cccctacccg ccttatctta atacatgcgg gcagtctatc cgacatgatc
     1741 ataaatgacc cggaatggaa tgtggagaaa ccggtcgtct taccgattcc cccagcctta
     1801 gcgcacacat taaatcagat agaatattat atgaaggata aatactttac cttgaattga
     1861 gattaaaaat gtttcaattc ctgataaagc ttttgcacag gtaatcccat cacgttataa
     1921 aagctaccat tgatagcctc taccccgata taaccgatcc actcctgaat gccataccct
     1981 cccgctttat cataaggttt atatttatcc aaataataat taatctcttc atcacccaat
     2041 tttgcgaaac aaaccgcaga ttcgacggaa aagcctacat ttttgtcctt cgtcatgata
     2101 caaacgccag ttattacctg atgtacatga tccgacaaag catgaagcat agcataagct
     2161 tcctcccggt tcgcaggctt ccccataacc ccgtcaaacg tccagacgat cgtgtccgcc
     2221 gtgatcagca attcatcatc tgccatagtc gatttatagg cctccgcttt cgaacgggca
     2281 atatataaag ggatctccat ggagtcaata gaatccgggt aagactcgtc aatatccgga
     2341 attaccctca cctcgaagtc gatatccaga ccagataaca aattccgtcg tctcggagaa
     2401 ttagaggcta agacgatctt gtactttttt aaattctcta acataaccta ttcgattaag
     2461 cgttacacat tcaccaaaat tttaccaccc aaaagcctcc tcgccgaacc agtgtccttg
     2521 agcccgcatc gtttgctcga tcacgtccct agctacgcct tcgccacctc gccgggagga
     2581 tatatatttc gctatctcct tgatctccgg agccgcatcc gcaggtgcca ccggcaatcc
     2641 gactcgcgtc attacctcat aatcaggaat atcatcaccc gcatacatga tgtgctcagg
     2701 agacaagccc gttttttcca tgaaatcctt aaagtcatgc acctttacag cgctacgcat
     2761 ataaatatgt tgtattccta aacgagaaaa gcgaatctgt acggcttccg tatatccgcc
     2821 cgtaattata gcgacctcat aacctttctt cacggccaat tgcaaggcat agccatcctt
     2881 gatattgaca gtacgcatcg gatcgccatt cgggtgaagc ggaatcacat cgcaggatag
     2941 caccccgtct acatcaaaga caaaagcctt tatttttctc aaatcatagt ttatactact
     3001 catgtcgagc ctccttatgt atacttcggc taatcagctc atatagattt cgcatacccg
     3061 gatctttaag catagccata tgtttgttta tcacattttc gtcatatcgt atagctggtc
     3121 ccgtttgggc ttgcgccggc gacattacat gtaccttagc ggctgtctcg tctatcaaag
     3181 gtagcaagac ctctcccggt atttgctgtt cttccaagat cttttcagct agcgcataca
     3241 tatgattcgt aaaattacaa gcgaaaaccg ccgctaaatg taagttcttt cgcttctcgg
     3301 aggagaggaa acggacatca ctggagagcg ccctagccac ctctcccagc accgtctcat
     3361 cttcagacga gttcgcctct aaaaagaacg gtattttctt gaaatccacc tccctactct
     3421 tactaaacgt ttgtaacgga taaaccaccc catatctagc cgtaagacct tcaaatacag
     3481 agattggcat actccctgcc gtatgcaccc acaaaccgtt attcggtttt acacgggcga
     3541 taacatcttg gagcacggca tctttcaaag agaaaacata caagtcggca tcttccacaa
     3601 tctcttccgg gatcacggtc cacccacatc ccaattcatc agctaaaatc ttagcatgct
     3661 cacttgtgtg actatatact tgcccgatac tcattccgga cttacgcatt tccaacgaaa
     3721 gccgggtagc taagtttccg gcaccaacaa atacgactct cattctcccg tctctttatt
     3781 ttcttccgga agagagaact ttcctatatg tatcttctcc cattgtaaat gggattcatc
     3841 aaaaggctta cgaacctgat ccttataacc gataccaatg atagacaaga catccaattg
     3901 ataagggata tccagcaacg aacgaacata attattcgaa tccacctcgt cctctgttac
     3961 ccggttccgg atctgacacc agcaactgcc cagtcccaaa tcctccgctt gcaattgcat
     4021 ataaatagaa gcgaccgaag cgtcctcgat ccaaacatcg ctttccatca cattcgccaa
     4081 gacaaccacg gccaaggcac aaccctccag aaaagcggaa ccatttttct tacacccggc
     4141 aagtttcttc aacatttcct tatcttccac gaccacgaac tgccaaggat tactacgttt
     4201 tgaggccgga gccatcaacg ccgccttcaa gatcagttct acctgctcgg gtgaaagtag
     4261 ttgttcggta aacttacgtg tacttcttct attttgtata agtgttgcaa aactctccat
     4321 ttttttcgtt ctttgtactc ttttaatatt aagattcgca aatataaata taattttttg
     4381 cacccatata tacgtatcgt tcttttttct cgttagtatt tttataattg aacaatagat
     4441 tatgaagatt cgtgcgatag ctgcgctgct atttatactt atttccgtga gtgcctttgg
     4501 cgagggccgc ataaaaatca ctggttatgt ccgtgacgcc gacggtaacc ctctggaatt
     4561 agtgaatgtc cgggttaaga acacgttgat cggctccatg accaacgaga agggatatta
     4621 ttccttttcc atatcgccgg gggattctat ctccgttatt tactcttgtc tgggatataa
     4681 taaggctgag cgtatcattc cctcggcaca agcggatatg cgcctgaacg tacagatgaa
     4741 caatacctca tttgatttag gggaagtatc cgttactgcc atccgcaagc agaccacgac
     4801 catggagtcc ctaaatgcgg acaaaattaa gttattgccc gatccctccg gaggtagtat
     4861 agagagcttg gtcgttacgt ttgccggagt atcgtccaat aacgagttaa gttcccagta
     4921 ttccgtacgt ggaggtagtt atgatgaaaa tatcgtttat gtgaatggga tcgaggtatt
     4981 ccgtccgctt ctgattcgct cgggacaaca agagggcctt agttttatca atccggacct
     5041 gacggaggcg gtcaatttcg ccgccggtgg cttcgaggct cgttacggag acaagatgag
     5101 ttccgtgctg gatattacct ataaaaagcc taagatattc gaaggctcgg cttccgcgag
     5161 cttgttggga gcgaatgctt atgtaggcag ttctatcggt aaatttaccc aagtaacggg
     5221 tttccgcttt aaaagcggtc ggtctatttt gggtaccatg gatacagacg ctgaatacga
     5281 ccctaaattt atcgatctgc aaacttacat cacgtaccaa ttggccccta aatgggaaat
     5341 caatttctta ggaaacctcg ctaacaataa ttataaattc accccttata gccgggaaac
     5401 ctctttcggt acagccgagc atcccaagaa cttcaaagtc tatttcgacg gaagggaaag
     5461 agaccgtttc caaaccttat tcggtgcgct tacattgaaa cacaacccca atgagaacac
     5521 agagttggga cttcaagcct ccgctttcaa aagcaaggaa gaagagggat acgatatcgc
     5581 cggagaatat tggctgagcg agaacggagc ggaaaatccg gatgacgacg cgtcagccgc
     5641 catgtccgta ggccgttatc acgagcacgc acgaaaccgt ttgaactcca ccgtcatgaa
     5701 tgtcgggcac tatgggatgg cccgcctttt aaacaatacg ttgaaatggg gagccacggt
     5761 acaaatggag aaaatcaatg ataagatcag tgaatgggaa aaaagggatt cctcaggtta
     5821 ttctttgccc caaaccggta ataacgtaag tgtatattcg aacctctttt ctgataatca
     5881 gatagaaagc acacgctttt ccgcttatgc gcaagacgca ttcaaattca ggaccaagca
     5941 aggtctgttc acgttagtcg caggggttag aggtagttat tggacttata ataaggagtt
     6001 ccttttcagt ccccgtgcct cattgggctt tatcccgaac ttcgaccaag acttgacgct
     6061 ccgtttcgcc accggactgt attatcaatc gcccttctac aaggaattac gtagagtaga
     6121 caaagataag aacggcaata atatcacggt attgaacaaa gatctaaagt cacaacgctc
     6181 catccatttc atattgggag gagattatac gttccgtgcc gtagaccgga atttcaaggt
     6241 gaccgccgag atgtactata aaaagctgga caatctgaat ccctacaccg tagataacgt
     6301 caagatccgc tattacggtg agaactgcgc caaaggttac gccatgggac tcgatgtcaa
     6361 attcttcgga gaattcgtac cgggtaccga ctcatggatc agcttctcct tgatgaaagc
     6421 ccagcaaacc atccgggaaa caacgaccgt tcctatggcc aatagccaag gctacaacat
     6481 ctcactcttc ttccaagatt atttcccggg ctataaacga gtcaagctaa atctgaaagg
     6541 agttctatcc ggaggacttc cccagacaat cccgggcaaa ggatacgaag ccggctattt
     6601 ccgtacgccc gcctacaaac gtgtagatat cggcctctcc tatcaattgg caggaggcac
     6661 ggacgctatc atggacaggg gcttcttccg ccatttgaaa aacatttggc taggtctgga
     6721 tgtatttaac atattagaca tcaaaaacgt tagttcctac tattggataa cagatgtata
     6781 taatgtccaa tacgcagttc caaactatct gaccggacgt caattgaacg ttcgtctgat
     6841 tgtcgatttt taataaaatg tatctttaaa cacatttact gggagataaa aacaaaaaat
     6901 tatttcctca ttcataaaaa gtagtgtaca tttgcacaca atagaaacaa acatttacta
     6961 aatctttaaa ttattattga catggaactt acacatatcg aacatttagg tatcgcagtg
     7021 aagagtatcg aggcttgttt accctattat gaaggcgttc ttggattaaa atgctacaat
     7081 atcgaagtag tagcagacca aaaagtaaaa accgcatttt tcaaggtagg acagactaag
     7141 attgaattac tagagccgac cagcgaagat agcacgatcg caaaatttat cgagaaaaaa
     7201 ggtgaaggta tccaccatat cgcattcgcg gtacctgatg tacaggcagc tttgaacgag
     7261 gctgaggaaa aaggcgttaa attaatcgat aaagctcccc gtggtggcgc ggaaggcttg
     7321 aacatcgctt tccttcaccc gaaatcaact tgcagcgtat tgacagagct ttgcatgccg
     7381 ggcaacaaat aattaatccg ttcatttcta acaacaaatc aaaatacaat gagtaaccag
     7441 cttgaaaaag taaaagagct catcgcactt cgtgagcaag ctcgcttggg tggaggagag
     7501 aaaagaatcg aatcacagca caaaaaaggc aaatataccg ctcgtgagcg tatcgccatg
     7561 ttgcttgacg annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnncgtatcg ccatgttgct
     7801 tgacgaaggt agtttcgagg aattcgacat gtttgttcaa caccgttgta caaacttcgg
     7861 tatcgagaaa actaaatatt taggcgatgg tatcgtaaca ggttatggta cgatcgacgg
     7921 acgtttggta tatatcttcg ctcaagattt caccgtattc ggtggagcct tgtctgaggc
     7981 tttggctatg aagatctgta aagtaatgga nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8221 nnnnnnnaag atctgtaaag taatggatca agccatgaag atgggcgctc ccgttatcgg
     8281 tttgaacgac tctggtggag ctcgtatcca agaaggtgta aacgccttgg caggatacgc
     8341 agagattttc caacgtaaca tcttggcttc cggtgttgtt cctcagattt ccggtatctt
     8401 cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnatcatga
     8701 cacgtggtac cagctatatg ttcttgactg gtccgaaagt cgtaaaaacc gtaacaggtg
     8761 aggatgtaac ccaagagcag ttgggtggag ccagcgtaca cactaccaaa tcgggtgtag
     8821 cccatttcgc tgtcgataca gaagaagatg gtttgcaatt gattcgtaaa ttgctcagtt
     8881 tcttacctca gaacaactta gaggaaacgc cgttagttga gtgcaaagac ccgatcgatc
     8941 gtctggatga tgtattgaac gatatcattc ccgataacgc caaccaatct tacgatatgt
     9001 atgaggttat cggtacgatc gtcgataaca acgagttcct agaggtccat gcggactacg
     9061 ctaagaatat catcgtaggt ttcgctcgtt tcaacggaca atccgtcggt atcgtagcta
     9121 accagccgaa nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9421 nngttccggg attccttccg ggtacaggtc aggaatacaa cggtgtaatc cttcacggcg
     9481 ctaaattgct ttacgcttat ggtgaggcta ccgttcctaa gattaccgtt acattgcgta
     9541 agtcttacgg tggagcttat tgcgtgatga gttctaaaca tttacgtggt gatatgaatt
     9601 acgcatggcc gacagccgag atcgccgtta tgggcccgag cggtgccgta gaggttatct
     9661 tcgccaagga agtagcagcc gctgaagatc cgaaagcatg cgcagcagag aaagaagctg
     9721 aatataagaa agcattcgct aatccttata acgcagctca atacggttat atcgacgatg
     9781 ttatcgaacc gcgtaacact cgtttccgta taattcgtgc tttgcagcaa ttgcagacta
     9841 agaagctaag caatcctgct aagaaacatg ataacctgcc tctataatcc gtaaaacagg
     9901 agatgaatat gataaataag aaaatagggg tattgctact gttcgctttg ctcatttcat
     9961 tcggggcaaa ggcacagcgc gcaacctcca tgcgtattaa tgaagtattg gttatcaacg
    10021 aggataactt cgttgatgac tatggcaaac gtcatggctg gattgagttg ttcaacactt
    10081 cggccggaac ggtaaatatc gcgggatgtt atttgacaga cgacaaaaac aatccgatga
    10141 aatatccgat cccgaaggga gacgtattga ctcagatcca accccgccag cacacactat
    10201 tttgggctga cggacagccg ggcagaggta cattccacgt taacttcgta ttagatccct
    10261 ctaaggagaa ttatatagct ctgtatgatg cagatggtaa aacattgatc gacgaagtta
    10321 cgatccctgc cggacaaatg gctgatatca gttacggtag agtgatcgat ggtaaagatg
    10381 aatgggcaca gctgaagaaa gttactccca gtacgaataa cctaacattg gattctaatg
    10441 agaaaatcga taatttcaaa cagaatgact ctttaggtat cggtatgacc attaccgcta
    10501 tggctgtagt gttcttggga ttatttttgt tatacatcat ctttaagcag atcggtagat
    10561 tgtctatatc cgcgagcaaa cgtaacgctc aaaaagctgc gggaacaaca agtgtatcgg
    10621 ttgacgccgg acaagagtct ggtgagatct ttgccgctat cgctaccgct ttgtacgaga
    10681 tgagtgatga caatcatgac atcgagcaca cggttcttac gatccacaag gtacaaagga
    10741 cttattctcc ttggagttca aaactctacg gtttgcgtca aaccccacat aagtaattat
    10801 ctaaaaacga acaaagaatg aaaagtttta aatataccat taacggtaac gtatataaag
    10861 tacacatcaa ttctgtagtg gatgacatcg cagatgttga agtaaatggt acaccttatc
    10921 aagtaaaatt agagaaaccg gcgaagaaac aaatggttac attgaaacgt ccggctcaag
    10981 caccgacaac agcaagtggc gaccctgtag ttactcgtcc ggcagcctct actacacaag
    11041 gtgctgttaa gactccgctg ccaggtgtta tcttgcaggt taagtgcaac gtaggtgata
    11101 ccgtgaagag aggtcaaaca ttgattatcc ttgaggctat gaagatggag aacaacatca
    11161 acgcagaccg tgacggtaag attatagaaa ttaaagtaca caagggagac tctgtgctag
    11221 aaggtgctga tctcgtagta atcggataag actatgcaag agagcttttt aacattctta
    11281 ggtgagaact tacaactgtt ccttacctat acaggtgtat acaacgctac tccgggacat
    11341 ctcatcatga ttctggtagg tctgttgttt atattcctgg cgattaaata tgagtttgaa
    11401 ccgatgcttt tgatccctat cggatttggt atcttgatcg gtaatatccc tttcaaggac
    11461 gcaggtcttc aggtaggtat ttatgagcaa gggtctgtac tgaacatcct ctatcagggt
    11521 gtgacttctg gatggtatcc gccattgatc ttcctcggta tcggggccat gaccgacttc
    11581 tccgcattga tctccaatcc taagttgatg ttgatcggtg cagcggctca gttcggtatc
    11641 tttggtgctt atacgattgc tcttcaaatg ggatttgagc cgaaccaagc aggtgctatc
    11701 ggtattatcg gtggtgctga cggtccgacg gctatcttcc tttcttctaa gttagcgcca
    11761 aacttaatgg gtgcgatcgc ggtatccgct tactcataca tggcgttggt tcctattatc
    11821 caaccgccgt tcatgagatt gcttacgact aagaaagagc gtttgatccg tatgaaaccg
    11881 ccgagagccg tttcttccac ggaaaaaatt atcttcccga tcgttggttt gttgcttact
    11941 tgcttcttgg ttccgtccgg tttaccattg ttaggtatgc tattcttcgg aaacttattg
    12001 aaagaaagtg gcgtgactcg tcgtttggca gagactgctc gtggtccgct gatcgataca
    12061 atcacgatct tattgggtat cacggtaggt gcttctaccc aagctactca attcttaaca
    12121 ttgaactcta tcaagatctt cggtttagga gcattgtctt tcgtgatcgc gacttgtgcc
    12181 ggtgtattgt tcgttaaatt gttcaattta atattgaaag acggtaacaa gattaacccg
    12241 cttatcggta acgctggtgt atctgctgtt ccagactcag ctcgtatctc tcaagtcgta
    12301 ggtttggaat atgacccgac caactacttg ttgatgcatg ctatgggtcc gaacgtagca
    12361 ggtgtaatcg gttccgctgt agctgccggt atcttgctag gattccttgg ttaataaaac
    12421 aactatctat attaaaaaag gcgaggtccg aaaggatccc gcctttttat gttattgttc
    12481 tcagttagtt tgctctatag aaaccggagt aatctccgta ctcgtatcct ccaccaacgt
    12541 tgtcccgagg aacaaccaga tcatcaaaag gattatagcg acaaccacac caaataccaa
    12601 tagcgtattc acacttttct ttctcatgtc tttaactgat ttattcattt tagaataaac
    12661 agccggaaca tgaatttggt tgtgtaccct tactcttatt tgtttttccc taacgcctcg
    12721 ttcagcactt tgttcttagc gatcgttgct tggaattctt tcaaatagaa aggctcaaaa
    12781 taagccacat tctcaaaacg gccatcatca tatgctttct gcgacaagga tgccatattt
    12841 acagccaatg gatagatacc agcaataaaa caggcgttcg gagaagtgat taccgtctca
    12901 catttagcgg caccgtctcc aaagaaacaa accttaccgt tctctaaaaa agaagcatac
    12961 gaatcagcat ctacgatatc agcagtcgtg gcacgtatcg tgttgagatg ggaatcataa
    13021 atcgaagagt agacttccat acggcgggca tccaacatag cgcaatacaa gcaatcggcc
    13081 tcctccttat ttttccggat agcggcagac gctaaaatat ccagcgtatg aataccgatc
    13141 aaaggaatac catacccaaa gcataatcct ttagccacag acaccccgat gcgtaatccc
    13201 gtataagatc cgggtccgct acttaccgcc acggcatcca gtttcatccc tttcgacttc
    13261 gcggcctcta atgcctcttc catataaacg cccaataacg ccgcatgaga cggcccctca
    13321 aaggaagcct tctcaaagac cacctcctcc ccttccgaca gggctactga acatacggaa
    13381 gtggatgtct cgatatttaa gatcaatgac ataataatta actattaaca attgataatt
    13441 gaacgaacaa acaatctcaa tccttcaatc tgattaggtt gcgaaggtat acaaaaattc
    13501 attatactat caaggcagcc ctatgagaaa catctattta tgagaaaata aacatcaaat
    13561 ctaaaaggaa accactatct ttgcgcaaac ttttgagaaa aatgatacaa tcaatgactg
    13621 ggttcggtaa ggttactgcc gagctccctt caaaaaaagt aaccgtagag ataaaggctt
    13681 taaacagtaa gcaattggat ttgtccaccc gtatcccttc catatacaag gataaggaaa
    13741 tggagcttcg gagcctgtta cttcaatctt tggagcgggg aaaagttgag ttcaatatct
    13801 ttatagaata tataggcaaa gatactccta cacagatcaa tcttgccgcc gtagagaatt
    13861 attacaacca aatcaaggag atcgcagaga aactgaatat cagcgttccg aacgattggt
    13921 tccagacctt gctccggatg ccggacgcaa tcaagtccga gaccgtagaa ccggacgaat
    13981 ccgaatgggg ggtggtttta gaaacggtaa aggacgctat caagcacctg tgtgatttcc
    14041 gtatccaaga aggagccatg cttcaaaagc tttttgagca aaagatagcc aatatcgcca
    14101 ctctgttgaa agaagtggag aaatacgagg gggaacgtat cgagaaaatc aaagctcgta
    14161 tcatggataa cctgcaaaag atagccgaga aggactatga caagaatcgt ttcgaacaag
    14221 aaatgatcta ttacatcgag aagctggatg tcaacgagga aaagaaccgt ttggacaacc
    14281 acttgaaata ttttatctca accatggaat ccggtcacgg ccaaggcaag aagctcggtt
    14341 ttatcgctca ggaaatgggg cgtgagatca atacgctcgg atcaaagagc aaccacgccg
    14401 agatgcagaa gatcgtggtc cagatgaaag acgagttgga acaaatcaag gaacaggtac
    14461 taaacgtatt ataataagat taacgagaat ggctggcaaa ttaattatct tctccgcacc
    14521 ctcgggttcc ggaaaatcaa ccattattaa ttatcttttg aaacaagatt tacaccttcg
    14581 tttctccatc tcggctacca gccgggctcc gcggggaacc gagaagaatg gtgtggaata
    14641 ttatttcctt acgccggaag agttccgcag tcgtatcgct aatggagact tcttggaata
    14701 tgaggaggtg tataccgata aatattacgg tacgttaaag agcgaggtag agcgtatctt
    14761 gaacgaaggg gataacgtga ttttcgatgt ggatgtggta ggcggatgca atatcaagaa
    14821 attctatgga gaccgtgccc tgtctgtctt tatccaacct ccttgcatcg atgacctacg
    14881 gaagcgattg gaaggacggg gaacagacag cccggaagtt atcgaaagcc gtatcgccaa
    14941 ggctgagtat gaattagggt tcacgggaca gtttgataag gttgtcgtaa acgatgatct
    15001 ggagactgcc caaaaagacg cgttgaagat cattcgtgag ttcttaaaca aatagtctat
    15061 gtctaatata ttcaagaata cccgttttat gatggggctt tctatcgttt gtgggatagc
    15121 gagcctcgta ttaggtggta ttagcctgta ttataaggag tatatcatcg ggggtgccct
    15181 gatatttaat atattcattt gtttcatcaa ctataagggt tggcaaaaga agggctaagt
    15241 aaaaatcgta tgggactcaa gaccgggatt tacagtggat cattcaatcc cattcacata
    15301 ggccatctcg ccttggcgaa ctggctatgt gagttcgagg gattggatga ggtgtggttc
    15361 gtagtcacgc ctcacaatcc gctgaagaaa aaggatgacc tgctcgatga ctcactacgg
    15421 ctggaaatgg cccaagccgc tattgacgga tatcctaaat tcagggtctg cgatattgag
    15481 ttctacctac cgaaaccttc ttattccatt gataccctac gaaccttatc ccgtaactat
    15541 ccaaatcggg acttttattt tatcatggga gccgataact ggcagctttt tccccgatgg
    15601 aaagaacacg aaaaaatact ccaagactac aaactgctga tttatccccg cctaggattc
    15661 gacatctcga tccctgccat ttatccgaac gtgaaaaagg tagacgctcc cttgatggaa
    15721 atctcctcca catttatccg taacgcttac caaaccggca aggatatccg tttcttcctg
    15781 ccggaaggag tgcggcctta tttcgggtca gtagcaaatc agtgacatac ctgcgataga
    15841 agatatactt acttgggcta tgaagtatat atcctatgcc acttgaagta tatattcttc
    15901 gagaagggaa gttataccgt gattatttac tgctttgcca tcttagggca atctgccaaa
    15961 attcccatta aaacatgttt tacagcacag ccgttaaaga tgatccccgt aacatcaaaa
    16021 caggctcacc cgataatctt tttggagtat ccaaatatat aatttgagcc ttgtcaagtg
    16081 aataactaat ggctagtcaa gtgaataact aacggttagg ggtagccgtt agttattcac
    16141 ttgggaagtg attagttatt catttgggag gctttgtacc tatagcttac gctattacat
    16201 aaaacactat tacataacaa attacatcaa tacaataagt catttctcga acaaattaaa
    16261 cgtgggacag aacaatcgaa ttcgcatagc taacttatat gcatatctcc actaattttc
    16321 tactgtagca atagaaagac aatatacatt aaacaacaat aaaaaagaca taatataccc
    16381 catgtttgat attttttaat tttctttgta atatcaaagt attacacatc tattaacttt
    16441 ttaaatcttt caaattatgg acaaactcaa aaaaactgac aaaagtcgta ctaaaccaac
    16501 aaggtaaagt tcttccaaaa gaacaaatga tgaaaatctt agggggagga agtgcgtatt
    16561 gtcattgtca taatctttct tcctcaattg aagtaacaag ctgctctgaa tgcagtaata
    16621 aatgctcaaa ttatggtggc gtacaaaact gtaacactac aggaggttag caacaaaaga
    16681 aagggctggt tttagctggt gatatctgct aaaaccagct tttttcttaa aacaaaaatg
    16741 accatgatct atcttctatt tttagtcact cttttgctta tcagttgtaa tccggatcaa
    16801 gccaaggata atggcaagga cgaaacaatc gagtatttta ttccactctc acatcgggta
    16861 gaaaaagacg tggatgaaat gtttgaggaa tatcggtatg tccccttgga aacaagggat
    16921 gacgcattga tagatgtgct ttacaatgtt aaaaacatcg ctatctttca agaggatatt
    16981 tacataggct ccggagagca attaatcgtt tgggataaat atggaaaatt caaacgagtc
    17041 ttatccaaaa agggaaatga tccgcaatca tacctccact ttaaccattt catgatatgg
    17101 cccaatggag atctatcgat cgcttctccc attgaaatcg taacctattc aaattcacac
    17161 caattcatca acaaaaagcg ttgcgagaat gtcggctata tagaggcgat cactcttttg
    17221 aacgatagtc tatacatcat aaaatgtatg cctacccccg aacagctacg ataccgtatc
    17281 atcaaccatc atacgggagc cattataaac tcgtatgatt ccatcatcaa ctgcaatcga
    17341 tatatcagtt cattcacaaa ctcatttgaa cggtatgaag gacatattat ctctcatggt
    17401 tatcaaagca acgacatcct tgaatgcact ttggatagtt caaaaatacg atacaaaata
    17461 aacgtagata acaggatacc gcccgccggc ttttacacgc aagagggaaa agaaggcatg
    17521 caactcatac aggaagaagc ggagaaagga tacatcggcc atatcccgga ctacgtggag
    17581 tccaaggaaa cgatattgct ctcctttaag gggaaaagag aagacctaaa cggaatagcc
    17641 ttaatcgaca aaaaagacgg aaacgcaaga gttttagaga acatcaagtt cgatgacaac
    17701 ttccggtggt tgcccaaaca gttcttctcg ttagatgagg gctggtgcgc catgctgatg
    17761 tatccggaag acgttttgaa gaaggaagag ttcgcaaggc gtttccccgg actggacgag
    17821 gagagtaacc cggtgttgtt cattggtaaa ctaaggtaat cattaaagac ctaaagcaat
    17881 ggaacatgac aatctattca tccaaatttt agaaatctta tcgataaagc acacggaaga
    17941 ttttaccata agatactacg agaggcatcc acacaaaaac aatctgtttg gactgtccga
    18001 gatgctacgt tattataata tagagaatgt agcggccgaa attcaaaaaa cacaagaaaa
    18061 cttatcctca ttggatgtac cctttgtggc ttacgtagat catgagtttg tattggtgcg
    18121 acatgtttct accgaggcaa tcatctattc atggcgaggt aaaaacatca cattatctat
    18181 cccggtattc ttggaacgat ggtcaggaat cgtccttctt ttcgaatcca ccgatgaatc
    18241 tattgaaccg gattataaag agcatagaaa ggaatactta cgacagcgga tagtaatcgc
    18301 atgtttcgtt tcattacttc tatcattaat agggtgtgcc cttatcacca acagaggaat
    18361 ggagatagga atctgggggt tatggggtgt taatgtgatc ggagcatctt tctgcggtat
    18421 cctgctttct cgagagatct taggctcgga taaatatgtc aacaaaattt gttccctgtt
    18481 tttgaaatcc agtgattgca acgggacatt ggattcccaa gcatctcatt tcttggggat
    18541 cagttggagt gtcttcggct taggatattt tctttccgca atattgttta tcgccttgtt
    18601 gccccaatat gttatatatg cagagactct gaatataatc gcattacctt atacagcgtg
    18661 gagcgtatgg taccaaaaat ttagggtaaa acaatggtgc gctttatgtt tatctgtaca
    18721 agctaccgta tggatcacct ttcttatctc tctattcgcg ataggcatgg atttcaatca
    18781 atgggattta tttgatttca ctaccattgg atgcgtgtat gggctcgtca ttctatcgct
    18841 ccattttact gttacattat acgtaaaaga aaagcaaatc caacgaagca acaataaact
    18901 tagcagcata aaactgaatg cctctgtatt taagagctta ttaaacgaac agcctcaata
    18961 tgacattgac aaaaatacag gaatattatt gggcaatagg gatgccaaag agtggattac
    19021 cattatctct aatccacatt gtgctccttg cgcaaaatta catctccaaa tagaaaagtt
    19081 actcaaagaa tataaagaag agatttgcat acaaatcatc ttgacctctt ttagcaagga
    19141 attagaacct agcgccatgc tactgacctc catgtatcta ctaaataatg aatcggatta
    19201 tttacgattc ctatctgact ggtatgcaaa agggcgtcat aaaaaagagg attgctataa
    19261 aagatacaga ttaaatccta atgacaaaga tatgttagcc aattttcaag cacaaaacga
    19321 atgggttagg cgcaatacaa taagttccac tccaacagtt ttgacaaatg gttatttatt
    19381 gccggaagaa tatgagttaa aggatatgtc gtatttaata aattaagtac tatgaataaa
    19441 ttagcatcac aaatagattc gctaaataag catttgatag gctcattaca tacaagctac
    19501 cctttcgggt tggctcatgg caaaatggga ttactcatct atttatacca tttgtatgat
    19561 tatacgcaag aagctattta taaagagaag gctgagcgat tgctggacga tctcttggaa
    19621 aacgatctct ctaaaaacgc agaactcacc gtggaggaag gtttatgcgg agttgcgtta
    19681 ggattggatt atattgtaaa aaagcaattt gtagacggtg atattaatga tttgctaagt
    19741 ggtatcgatg atttgctatt caagaagctg gttttcggaa atatggaatc taggtattcc
    19801 ctgtctcaac tcatccattt cttatattac atttataaaa ggctggaaat ccagacaaac
    19861 gataatgagc gtttcccttt cgagggctta gcaatcaagt tagttaatca attggccgat
    19921 ttgatagacg cctccttttt cgaggaatcc tatacgtttt ccatttacca atatcacgta
    19981 ccgatattga tgaaaaccct gtcctgtctt atacaatatg atttttacaa ggatcggata
    20041 caaaaggttt tggaacaact atctctgtat atgttctccc atttgcctca tctgcatttg
    20101 aaccgactat atctgttatg gggcatacta cctttacgga attgttcgcc ggattggcaa
    20161 agatatgtga acgaactaag aaaatcaatc aatctagaca taatatataa tagagagatc
    20221 aaaggcaagg atatctatat cagtaatgga tacgcttctc tatatttctt gttggaggga
    20281 ttaaaaaggg acttccccga atacaccatc cctttcaatc cgcacctaat ttacgatcgg
    20341 atcatctcgt ctgacgcttg ggatgcccta atggagaacg aatactacta taatatacac
    20401 agaggattgc tgaatggttt ccccggtacg gtgttggcat tgttaaacat taagcaaaga
    20461 tatttatgcg aatagacttg acagatacaa catttattat tcctgtacgg atcgattcca
    20521 tgatccgttt ggagaacctg ttgatgtccg tggactcaat agtacgttat ttccggacac
    20581 gcatcttaat tatggaggcc tcatcatacc aaaatgagat tatcccctcg ttaataaaag
    20641 atgatacggt gaagtacact ttcctcgtgg ataaagatcc tgtattctac aagaccaaat
    20701 acttgaatat cctcgcaaag caggttgata ctccacttgt ttgtatttgg gacgcagatg
    20761 tgatactgga ccaccttcaa atattggatg cggtgaaaca gcttagaact aggacttctg
    20821 atgtcgctta tccatatgat ggtaattttt tagatacgtc agatatattg agggaacatt
    20881 attggctcca tcgtgactta gatttcctaa aaaaacatca agcaaagatg aactctttgt
    20941 acacagtaga gggagtgata ggcgcagtcg ggggagcggt cttcgcccaa acggaaaaat
    21001 acctgcaagc gggtatggag aatgaggatt tctatggctg gggcttggag gacggagaaa
    21061 gacattaccg ttggttgagt tttggctacc ggatttatcg gagtgagggc tgtttattcc
    21121 atttgtctca tccccgggat caaaacggga tgtaaagata aaattattgg gtcttaagtt
    21181 cattggccta caaacctaag atacttcacc aaggatccta agatacttta ccgatgaacc
    21241 taagatactt tatccatgaa ctaacaagat cggtgacctc aaccttttac cacataagtc
    21301 agcataaatc agaaatattt tgtacttttg cgccgtatta tacaaaataa tagcataatg
    21361 aatctattag aactgagtga acaggaaata ataagacgta atagcatgga gcagttgcgt
    21421 cagatgggga tagagcctta tcccgcagct gagtatgtaa cgaacgcatt ttccaaagag
    21481 ataaaagaga cattcaaaga tgacgctgag ccacgcccgg tacgtatcgc cggccgtatc
    21541 atgagccgtc gtatcatggg aaaagcctct ttcatggagt tgcaggattc cgagggcaga
    21601 atacaggtct atatctcccg tgacgatatt tgtccggacg agaataaaga cacatacaat
    21661 gtcgttttca agaaattact ggatatcggt gatttcgtcg ggatcaaggg attcgttttc
    21721 cgtactcaga tgggagagat ttccgttcat gcgcaagaat tgacagttct gtctaaatca
    21781 cttcgtcctc taccggtcgt taaatataag gatggtgtcg cttacgacgg ttttaatgac
    21841 ccggagcttc gttatcgcca gcgttacgtg gatttggtag taaacgaggg tgtaaaagat
    21901 attttcatga aacgtgcggc tatcatcaag accatgcgta ccgccttgga tgaggccgga
    21961 tacacggagg tagagactcc gatcctgcaa tctatcgcag gaggagccag cgcacgtcca
    22021 ttcatcacgc atcacaactc tttggatatc gatctgtatt tgcgtatcgc taccgagttg
    22081 tatttgaaac gattgatcgt cggtggattc gagggtgtat atgagatcgg taagaatttc
    22141 cgtaacgagg gtatggaccg tacgcacaac ccggagttca cttgtatgga actttatgtc
    22201 caatacaagg actataactg gatgatgagc ttcactgaga agctgttgga gcgtatctgt
    22261 atcgccgtga acggtacgag cgagagcacg atcgacggta agacaatcag cttcaaggct
    22321 cctttccgcc gcttgccgat cttggaggcg atcaaggaaa agacgggtta cgacttggaa
    22381 ggtaagaccg aggacgagat tcgtgcgatc tgca
//
