GCA_003458215.1 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaEMCNGKPK_45 (original name was: gnl|Prokka|EMCNGKPK_45)

Region	Type	From	To	Most similar known cluster		Similarity
Region 45.1	NRPS-like	88,407	130,836

gnlProkkaEMCNGKPK_56 (original name was: gnl|Prokka|EMCNGKPK_56)

Region	Type	From	To	Most similar known cluster		Similarity
Region 56.1	RRE-containing	88,382	108,735	polysaccharide C	Saccharide	16%

gnlProkkaEMCNGKPK_78 (original name was: gnl|Prokka|EMCNGKPK_78)

Region	Type	From	To	Most similar known cluster		Similarity
Region 76.1	lanthipeptide-class-i	81,990	112,141
Region 76.2	phosphonate	146,373	170,235	polysaccharide B	Saccharide	30%

Region	Type	From	To	Most similar known cluster	Similarity
Region 45.1	NRPS-like	88,407	130,836
Region 56.1	RRE-containing	88,382	108,735	polysaccharide C	Saccharide	16%
Region 76.1	lanthipeptide-class-i	81,990	112,141
Region 76.2	phosphonate	146,373	170,235	polysaccharide B	Saccharide	30%

No secondary metabolite regions were found in these records:: gnlProkkaEMCNGKPK_1 (original name was: gnl|Prokka|EMCNGKPK_1); gnlProkkaEMCNGKPK_2 (original name was: gnl|Prokka|EMCNGKPK_2); gnlProkkaEMCNGKPK_3 (original name was: gnl|Prokka|EMCNGKPK_3); gnlProkkaEMCNGKPK_4 (original name was: gnl|Prokka|EMCNGKPK_4); gnlProkkaEMCNGKPK_5 (original name was: gnl|Prokka|EMCNGKPK_5); gnlProkkaEMCNGKPK_6 (original name was: gnl|Prokka|EMCNGKPK_6); gnlProkkaEMCNGKPK_7 (original name was: gnl|Prokka|EMCNGKPK_7); gnlProkkaEMCNGKPK_8 (original name was: gnl|Prokka|EMCNGKPK_8); gnlProkkaEMCNGKPK_9 (original name was: gnl|Prokka|EMCNGKPK_9); gnlProkkaEMCNGKPK_10 (original name was: gnl|Prokka|EMCNGKPK_10); gnlProkkaEMCNGKPK_11 (original name was: gnl|Prokka|EMCNGKPK_11); gnlProkkaEMCNGKPK_12 (original name was: gnl|Prokka|EMCNGKPK_12); gnlProkkaEMCNGKPK_13 (original name was: gnl|Prokka|EMCNGKPK_13); gnlProkkaEMCNGKPK_14 (original name was: gnl|Prokka|EMCNGKPK_14); gnlProkkaEMCNGKPK_15 (original name was: gnl|Prokka|EMCNGKPK_15); gnlProkkaEMCNGKPK_16 (original name was: gnl|Prokka|EMCNGKPK_16); gnlProkkaEMCNGKPK_17 (original name was: gnl|Prokka|EMCNGKPK_17); gnlProkkaEMCNGKPK_18 (original name was: gnl|Prokka|EMCNGKPK_18); gnlProkkaEMCNGKPK_19 (original name was: gnl|Prokka|EMCNGKPK_19); gnlProkkaEMCNGKPK_20 (original name was: gnl|Prokka|EMCNGKPK_20); gnlProkkaEMCNGKPK_21 (original name was: gnl|Prokka|EMCNGKPK_21); gnlProkkaEMCNGKPK_22 (original name was: gnl|Prokka|EMCNGKPK_22); gnlProkkaEMCNGKPK_23 (original name was: gnl|Prokka|EMCNGKPK_23); gnlProkkaEMCNGKPK_24 (original name was: gnl|Prokka|EMCNGKPK_24); gnlProkkaEMCNGKPK_25 (original name was: gnl|Prokka|EMCNGKPK_25); gnlProkkaEMCNGKPK_26 (original name was: gnl|Prokka|EMCNGKPK_26); gnlProkkaEMCNGKPK_27 (original name was: gnl|Prokka|EMCNGKPK_27); gnlProkkaEMCNGKPK_28 (original name was: gnl|Prokka|EMCNGKPK_28); gnlProkkaEMCNGKPK_29 (original name was: gnl|Prokka|EMCNGKPK_29); gnlProkkaEMCNGKPK_30 (original name was: gnl|Prokka|EMCNGKPK_30); gnlProkkaEMCNGKPK_31 (original name was: gnl|Prokka|EMCNGKPK_31); gnlProkkaEMCNGKPK_32 (original name was: gnl|Prokka|EMCNGKPK_32); gnlProkkaEMCNGKPK_33 (original name was: gnl|Prokka|EMCNGKPK_33); gnlProkkaEMCNGKPK_34 (original name was: gnl|Prokka|EMCNGKPK_34); gnlProkkaEMCNGKPK_35 (original name was: gnl|Prokka|EMCNGKPK_35); gnlProkkaEMCNGKPK_36 (original name was: gnl|Prokka|EMCNGKPK_36); gnlProkkaEMCNGKPK_37 (original name was: gnl|Prokka|EMCNGKPK_37); gnlProkkaEMCNGKPK_38 (original name was: gnl|Prokka|EMCNGKPK_38); gnlProkkaEMCNGKPK_39 (original name was: gnl|Prokka|EMCNGKPK_39); gnlProkkaEMCNGKPK_40 (original name was: gnl|Prokka|EMCNGKPK_40); gnlProkkaEMCNGKPK_41 (original name was: gnl|Prokka|EMCNGKPK_41); gnlProkkaEMCNGKPK_42 (original name was: gnl|Prokka|EMCNGKPK_42); gnlProkkaEMCNGKPK_43 (original name was: gnl|Prokka|EMCNGKPK_43); gnlProkkaEMCNGKPK_44 (original name was: gnl|Prokka|EMCNGKPK_44); gnlProkkaEMCNGKPK_46 (original name was: gnl|Prokka|EMCNGKPK_46); gnlProkkaEMCNGKPK_47 (original name was: gnl|Prokka|EMCNGKPK_47); gnlProkkaEMCNGKPK_48 (original name was: gnl|Prokka|EMCNGKPK_48); gnlProkkaEMCNGKPK_49 (original name was: gnl|Prokka|EMCNGKPK_49); gnlProkkaEMCNGKPK_50 (original name was: gnl|Prokka|EMCNGKPK_50); gnlProkkaEMCNGKPK_51 (original name was: gnl|Prokka|EMCNGKPK_51); gnlProkkaEMCNGKPK_52 (original name was: gnl|Prokka|EMCNGKPK_52); gnlProkkaEMCNGKPK_53 (original name was: gnl|Prokka|EMCNGKPK_53); gnlProkkaEMCNGKPK_54 (original name was: gnl|Prokka|EMCNGKPK_54); gnlProkkaEMCNGKPK_55 (original name was: gnl|Prokka|EMCNGKPK_55); gnlProkkaEMCNGKPK_57 (original name was: gnl|Prokka|EMCNGKPK_57); gnlProkkaEMCNGKPK_58 (original name was: gnl|Prokka|EMCNGKPK_58); gnlProkkaEMCNGKPK_59 (original name was: gnl|Prokka|EMCNGKPK_59); gnlProkkaEMCNGKPK_60 (original name was: gnl|Prokka|EMCNGKPK_60); gnlProkkaEMCNGKPK_61 (original name was: gnl|Prokka|EMCNGKPK_61); gnlProkkaEMCNGKPK_62 (original name was: gnl|Prokka|EMCNGKPK_62); gnlProkkaEMCNGKPK_63 (original name was: gnl|Prokka|EMCNGKPK_63); gnlProkkaEMCNGKPK_64 (original name was: gnl|Prokka|EMCNGKPK_64); gnlProkkaEMCNGKPK_65 (original name was: gnl|Prokka|EMCNGKPK_65); gnlProkkaEMCNGKPK_66 (original name was: gnl|Prokka|EMCNGKPK_66); gnlProkkaEMCNGKPK_67 (original name was: gnl|Prokka|EMCNGKPK_67); gnlProkkaEMCNGKPK_68 (original name was: gnl|Prokka|EMCNGKPK_68); gnlProkkaEMCNGKPK_69 (original name was: gnl|Prokka|EMCNGKPK_69); gnlProkkaEMCNGKPK_70 (original name was: gnl|Prokka|EMCNGKPK_70); gnlProkkaEMCNGKPK_71 (original name was: gnl|Prokka|EMCNGKPK_71); gnlProkkaEMCNGKPK_72 (original name was: gnl|Prokka|EMCNGKPK_72); gnlProkkaEMCNGKPK_73 (original name was: gnl|Prokka|EMCNGKPK_73); gnlProkkaEMCNGKPK_74 (original name was: gnl|Prokka|EMCNGKPK_74); gnlProkkaEMCNGKPK_75 (original name was: gnl|Prokka|EMCNGKPK_75); gnlProkkaEMCNGKPK_89 (original name was: gnl|Prokka|EMCNGKPK_89)

Compact view

gnlProkkaEMCNGKPK_45 - Region 1 - NRPS-like

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Location: 88,407 - 130,836 nt. (total: 42,430 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 88406 - 130836:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg45_94

AMP-binding (12..401): X

nrpys: Leu, Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALFLGVVLK
Nearest Stachelhaus code(s):: Leu or Ile DAIYLGVVLK (59% 8Å match); aIle DALVFGVVLK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaEMCNGKPK_56 - Region 1 - RRE-containing

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Location: 88,382 - 108,735 nt. (total: 20,354 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaEMCNGKPK_78 - Region 1 - lanthipeptide-class-i

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Location: 81,990 - 112,141 nt. (total: 30,152 nt) Show pHMM detection rules used

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

gnlProkkaEMCNGKPK_78 - Region 2 - phosphonate

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Location: 146,373 - 170,235 nt. (total: 23,863 nt) Show pHMM detection rules used

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1