LOCUS       gnlProkkaHJNELPPN_17   13057 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HJNELPPN_17.
ACCESSION   gnlProkkaHJNELPPN_17
VERSION     gnlProkkaHJNELPPN_17
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 20:49:13
            Original ID  :: gnl|Prokka|HJNELPPN_17
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13057
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13057
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[3743:8057]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3744..8057
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13057
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13057
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             110..2521
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 7e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg17_1"
                     /sec_met_domain="Poly_export (E-value: 6e-18, bitscore:
                     56.9, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCLMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLED
                     HPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKG
                     SGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             2532..3680
                     /locus_tag="ctg17_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             3744..4463
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.9e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             4484..5785
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.3e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             5802..6926
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.9e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             6936..8057
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg17_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.5e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        7026..8033
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg17_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg17_6_Aminotran_5.1"
                     /locus_tag="ctg17_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             8054..8197
                     /locus_tag="ctg17_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             8400..9884
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.5e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             9838..11097
                     /locus_tag="ctg17_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             11106..11855
                     /locus_tag="ctg17_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             11855..12895
                     /locus_tag="ctg17_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 tgtctcttct cgatgttctt cccccttctc ttcttaagca acagttatct gccgtctgtc
       61 atgggatgca ggaactgtgt gaaatcaact gaaacttttt tatttgtcaa tgaaaataca
      121 acgacttttt agcattctac tattttgttt gatgctggga agtggctcgc ttatggctca
      181 gtccatgagt gactcacagg tactggaata tgtaaaagac ggcatccgcc aaggcaagga
      241 acagaagcag cttgcttccg aactagcccg taagggtgta accaaagaac aggcaatgcg
      301 tgtgaagcag ctatacgagc agcagaacaa tgtaaatacc tcgaaatcaa cgggcacgga
      361 catcaacgaa tcccgcctgc gtgaagagac taagaagaat acttccgata tgctggagga
      421 tcatccgact actcaggacc ttgcccgtgg tgatcaggtc ttcggacgta acatcttcaa
      481 tacccgcaac ctgacgttcg agcctagtgt caaccttgcc actcctgcca attaccgtct
      541 tggtcccggt gatgaagtca tcattgatat ctggggtgcg agccagaaca cgatccgcca
      601 gcaaatctct cctgaaggta ctatcaacat tcagaagatc ggccctgtca accttagcgg
      661 tatgacagtc tctgccgcca atgactatct gaagaacgcc ctgaataaaa tatataacgg
      721 tctgaataat actaccgatc ctacttccga catccgtctg acgttaggta atatccgtac
      781 tattcagatt aatgtgatgg gagaagtcgt acagcccggt acctacgccc tttcttcctt
      841 ctctaccgtc ttccatgcgc tttatcgtgc aggcggtgtg agtgatatcg gtagcctccg
      901 aaacgttcag ttggtacgca acggaaagaa tattgccacc atcgacgtct acgaattcat
      961 tatgaaaggc aacacacagg atgacatccg cctacaggaa ggtgacgttg tgattgttcc
     1021 tgcctatgat gtattggtaa agattagcgg caaggtaaaa cgtcctatgc gttttgaaat
     1081 gaagaaagac gagaaccttg ctactctcat caaatatgcc ggcggctttg aagctgacgc
     1141 ctacacccgt tcattacgtg ttgtccgtca gaatggtgag gaatacgaag tcaacacagt
     1201 caaagatata gattacaaca tttataaaat gcgtaacggt gacgtagtaa ccgccgaagc
     1261 catccttaac cgcttcacaa acaaactgga aatccgtggc gctgtctatc gtcccggtat
     1321 ctaccagctc agcggtaaac tgaacacgat ccgcgaactt gtccatgaag ctcagggtct
     1381 gaccggtgac gctttcctga atcgtgccgt cctctatcgc cagcgtgaag acctgaccag
     1441 tgaagttgtt cagatagaca ttaagtctat catggacggc acttccccaa accttgccct
     1501 aatgaagaat gacatcctct acattccaag tatccatgac ctggaagacc ggggtaatgt
     1561 cacagttcac ggtgaggttg cccaccctga ttcctatcct tatgcggata acatgacact
     1621 tgaggatctg atcattcagg ccggtggctt gaaagaagcc gcctctactg tccgtattga
     1681 tatatcgaga cgaatcaaga atcctcgtag tactgcggat aatgatacga ttggtcagat
     1741 gtataccttc tctttaaagg atggttttgt aatagatggt cagcccggtt ttatccttga
     1801 gccttatgat caggtttatg tccgtcgcag tccgggctat caggcacaac agaatgtagc
     1861 cattgaaggt gaaatccttt tcggaggaaa ttacgccatg accagccgtg aggaacgtct
     1921 ttccgattta gtgaataaag ccggcggtcc gaccaattat gcctatctgc gtggtgcgaa
     1981 actgacccgt gtggctaacg ctagtgaaaa gaaacgtatg ggtgatgtaa ttcgccttat
     2041 gagcaggcaa ttgggcgaag ccatgattga ctctttgggt attcgtgttg aagatacttt
     2101 tacggttgga atagatttgg aaaaagcctt gagcaatcct aaaagtaatg ccgatcttgt
     2161 cttacgtgaa ggtgatgtga tctccatacc taagaatact aatactgtaa ctatcaatgg
     2221 tgctgtcatg gttccgaata cggtttctta tatgaaggga aagaatgtgg attattacct
     2281 gaatcaggcc ggtggctgtt ctgataatgc aaggaagagt aagaagttca ttgtttacat
     2341 gaatggtcag gtgacgaagg ttaagggtag tggtaagaaa cagattgagc cggggtgtga
     2401 gattattgtg cctggtaagg ctaagaagaa agggaacata gctaatattt taggttatgc
     2461 tacttccttc agttctttgg gaatgatgat tgcttctatt gctaatttga taaagaaata
     2521 aatgacctat tatgattgaa aagcaatctt atcaagaacc gttttctgaa gtggataaaa
     2581 ggaaagatga tgaaatggaa atagacttga tggctatttt ttataagatt attactgttc
     2641 gtggagtact atgcaaagct gctggagtgg gagtaataat tgctatagtg gtggcattga
     2701 gcattcccaa gcaatataca gtaaaggtta ccctttctcc tgaaatgggt aatgcgaagg
     2761 gaagtaatgg tttagccgga cttgctgcct cgtttttggg agatggggct ctaatagggg
     2821 aaagcacaga tgccttgaac gcttctcttt cagcagatat tgtttcttca actccttttt
     2881 tattggaact tttagaaatg gaagtctccg tttctaaaaa ggatgataaa atgactttgg
     2941 ggtcttatct cgatgaagag tcatctcctt ggtgggatta tcttataggt tttccgggca
     3001 tagtaatagg aggagttaaa tcattattcg gagaagatac ggttcctgcc agtggagggc
     3061 ggcaaggaac tatcgaattg acgaaagaag taaatgagaa gattaatttt cttaaaaaga
     3121 agattagtgc atccattgat aagaaaaccg ccataacgag cattacggtc accttacaaa
     3181 atccgcagat cactgcggtt atagcagatt ctgtcgttca taaattacag gaatatatta
     3241 ttgggtatcg aacttcaaaa gtaaaagaag actgtgcgta tttggaacgg ttgtttaaag
     3301 aacgtcagca ggaatattat gctgctcaaa gaaaatatgc ggattatgta gacgcccatg
     3361 ataatgtggt tcttcaaagt gtacgtgctg agcaggagcg tttacagaac gacatgagtt
     3421 tggcttatca gatatatagt caggttgcta atcagttgca ggtatccaga gccaaagtac
     3481 aggaggaaaa gccagtcttt gcagtagttg agcctgccgt tgtacctttg aaaccttcag
     3541 gtatgggact caaaatttat attttattat ttgtgttcct gtccgtatct ggtactctcg
     3601 tgtgggtgtt ttttggcaaa agtctgctgg ctagcttgag aaaagaactg aaaaataagg
     3661 agatagaaca ggataaatga tgctaaaacg tcgtttacaa cattcttaca tcaattaaat
     3721 tcacttacta tattattaaa cgaatgatac gtacagctat gataatggct gcgggcatgg
     3781 gaacccgttt tggccaatat acagaattga tacctaaagg gttcgtcaaa gtgggaggta
     3841 ttccaatgat agttcgttct attgatactt tgttatcatg tgacattgag cgaattgtaa
     3901 tcggtacagg atataaacaa gaagtttatg aagaattgaa gacagactat cctatgcttg
     3961 aaacctgttt tagtcctcgt tatgctgaaa caaatagtat gtatacttta tataatacgc
     4021 gggagattct gggcaatgat gattttttat tgttagagtc agatttgatt tttgagaaac
     4081 aagcaataat gagcttattg gagtgtcctg cggcagatgc aatgctaata actccagtga
     4141 caaagtttca agatcagtat tatgtggaac atgatgataa ttttcgcctt tcttcatgtt
     4201 ctgtcaataa gaataaacta aacgctaaag gcgaattggt cggcatccat aaactatccg
     4261 gttcctttta caaaataatg tgtgctgatt atgcgagtat tgttgatgaa caacccaatt
     4321 tgggatatga gtatgaatta ctacgaatat cttgttctca atctcctgtt tatgtgcata
     4381 aagtagaagg gctgaaatgg tatgaaatcg atgacatatc agatttggaa tatgcagaga
     4441 aatatattgt tccgtattgt taattaaaat aatatatcaa attatgagta agacagttta
     4501 tattgggatg actgcggata ttatgcatcc aggacttatc cgcattatta atgaggctac
     4561 taaatacggt gatgttataa ttggtcttct tacagataaa gctattgcgg agcataaacg
     4621 ccttccttat ctgacctatg aacaacgaaa agaggtagtt cagaatatta aaggcgtatg
     4681 taaagttgtt cctcaagaag aatggagcta tgttgagaat ctcaaacgca ttaaacctga
     4741 ctatataatt catggtgacg actggaaaac cgggccttta cgtgaagaac gtgtgcgcgt
     4801 atttgaagtg atgaatgaac agggaggaaa ggttatcgaa attccatata ctttgggaat
     4861 taattcatct tctttggata aagatattaa ggctataggt acaacccctg atgtacgttt
     4921 aaaatcactt cgtcgtttga taaatgccaa acccgtagtt cgtattttgg aagctcatga
     4981 tggactatgt ggcttgataa ttgaaaatca ggaaatatta aaaggggata agagggaagt
     5041 atttgacgga atgtggtcta gtagccttac ggattcaacc agtaaaggta aacctgatat
     5101 tgaggcggtt gatttaacta cccgattgca agatttgaat aatattctgg agtgtactac
     5161 taaacctatt atttttgatg gagatacagg tggtaaaatt gaacatttcg tatttacagt
     5221 acgcacttta gaacgtcatg gaatttcagc tataataatt gaagataaag ttggattaaa
     5281 aaagaattca ttgtttggta cagatgttat tcaaactcaa gatacaatcg aaggtttctg
     5341 taataagatc aaagcaggaa aggcatctca gattactgat gattttatga ttatcgctcg
     5401 tattgagagc cttatagcgg gaaagccggt aagtgatgct ttagagagag cttttgcata
     5461 tgtccaagcg ggagcggacg gtattatgat acatagcaaa aataagtcgg gtgaagatat
     5521 aaaagaattt tgtttggcgt ttcgaaaaca gtatgctcat gtacctatcg tggttgtgcc
     5581 tactacatat gatcatattt atgagtctga attgtgtgat tggggtgtga atataattat
     5641 ttatgctaat catatgcttc gtgccgctta tcctgctatg atgaatgtcg caaagataat
     5701 attagagaat gaacgtgctt tagaggtgcg cgaactgtgt atgcccataa aagaaatatt
     5761 ggaactgatt ccaggtacta aataaaaaga ggaatatcat tatgttaagc gtagaaaaag
     5821 tttatgaaac gtttctgagt catgacgttg atttttttac aggagttcca gactcattac
     5881 taaaaaatat ttgtgcctat atcacagacc atacttcacg tgagaaacat atcatagctg
     5941 ctaatgaagg tgcggctgta ggaattgctt caggttatta tatggcatca ggtaaggttc
     6001 ctgtggttta tatgcaaaat tccggcttgg gtaatactgt taatcctctg ctgtctcttg
     6061 cagatgaaca agtatacagt tttccaatgc ttttgatgat tggctggcgt ggtgaaccgg
     6121 gaacaaaaga tgaacctcag cataaaaaac agggtgaggt aactttagat ttgttgaaag
     6181 caatgcggat tccttatata attcttgatt caaatgagaa tgatgcattt attcagctcc
     6241 atgatatcat acaatcagca aaaactaaga atattcctca tgcaataatt attcggaaag
     6301 atgtttttgg caaatataaa cttcaaaaag agttcggatg taattatcct ttatctcgtg
     6361 aggatgcttt gcaaatagtt gtggattatc tgcctgaaaa ttcagtggtc gtttctacta
     6421 ctggcaagct ttctcgtgag ttatttgaat atcgagaaat gaaagagcaa ggtcatgaac
     6481 atgattttct cacggtaggc tctatgggac atagttcatc aatctctttg ggtattgcta
     6541 tagcaaagca agatagacct gtttattgct tggatggtga tggagcattt attatgcatt
     6601 taggggcaat tagtaacatt ggcgatttat ctcctaaaaa ctattatcat attttgttta
     6661 acaatggtgc tcacgagtct gtaggaggac agcctacttt aggatttagt ttagatattc
     6721 cggctattgt ccgggggagc ggatataagc atacttatac tgtttgtaca aaagttgaaa
     6781 ttgaagaagc aatgaagcag cttccaaagt tatgtggtcc tgttttgttg gaaataaagg
     6841 ttaaaataga ttctcgggag aatttgggac gtcccacgac tactcctata gagaataagg
     6901 agcattttat ggatttttta aaataaatat attcgatgaa aatagaaaga aaaatattat
     6961 taaatcctgg gcctgccact actactgaca gtgtaaaaat ggcacaagtt gttccggata
     7021 tttgtcctcg cgagaaagaa ttcgcaggta tgatgaaaca acttcgggac gatttggtca
     7081 gagttgctca tgggaatttg gaaaaacata ccgctgtatt attttgtggc tcaggaacca
     7141 tcaatattga tatatgtcta aattctcttc ttcctgaaga caaaagggtg cttatagtga
     7201 ataatggggc atatagtacc cgtgctgtag aagtgtgtca atattatggt ttgcctcata
     7261 ttaatttgga attttccgtt tacgaacgtc ctgatttatc ggtggtggaa aatgtgttgc
     7321 aagaaaatcc tgatatagct atggtttata ctactcatca cgagacgggt acaggaattc
     7381 tgaaccctat tcgcgagatg ggcgctatag ctcataaata tcaggctaaa tttgtcgtcg
     7441 atactacttc ttctttgggc atgattcctt ttgatataga gaaagataat gtggattttt
     7501 gtatggcatc tgctcaaaaa ggacttcaag cgatgacagg tctttctttt attataggca
     7561 atgaggaaca gattaagttt tcaaaaaaat atcccaagcg ttcttactat tgtaatcttt
     7621 atttgcagta tgagaatttt gagagaacag gtgaaatgca ttttactcca ccggtacaaa
     7681 ctatttacgc cactcgtcag gcattaaatg aatattttga agtgggtgaa gaagctaagt
     7741 ttgcccgtca caaaagagtt tttgaggcta ttcattcagg tataaatgaa attggtctta
     7801 aaagtgtaat aaagcgtgaa tggcagtcag gactggttgt ctcagttcaa tacccagaag
     7861 atcccaactg ggattttgag aaaatacatg attattgtta tgagcgtgga tttacgattt
     7921 atccaggtaa gatatcaact gaggatactt ttagaatctg tgctttagga gagatagaag
     7981 tagatgatat tgagaacttc tttaaagtac taaaagctgc attaaatcat tataacgtca
     8041 cattaccgat gtcatgattg cagaaatatt attgaagatt cgtcattttt atttttccct
     8101 tcgtggtata cacttccatc cggaaagtgt tatttctgga gtgcctattc gtagctttcg
     8161 cttagtaggc aaatatggca atattaattt gaggtgatgc attaggagtt ctttattctt
     8221 ataaaaaggc atcggtagtt ataggagata atgtttgtgt agggtaattt gcttttagtg
     8281 ggagagacca tattagaatt gcggtaaggg gcgaagaaga taataaccaa ttagtgagaa
     8341 tattggaaaa atataattga tatcggtaaa tgtagttgtt tttatactgt atttaagtaa
     8401 tggaaaatct aaagcagaaa actgtatcag gaataatgtg gagcgctata gaacgtttct
     8461 ctttacaagg agtacagttt ataattcaaa taatattagc tcgtttgtta ctaccatcgg
     8521 attatggtat gatcgggatg ttagctattt ttcttcaagt cgctcaagta tttatagata
     8581 gcggttttac aaatgcttta atccagaaaa aagatagaac tgaagaggat tttgccactg
     8641 tcttttattt taatattctt gtcgcagtat tattctatgg tatattgttt ttttcggctt
     8701 ctttgattgc agacttttat aatatgccga ctttagttct tgtaattcgt tttatagcat
     8761 tgtcgttgat aataaatgct ttatcggcta ttcacagaac gaaattaatt atttctgtaa
     8821 actttaaaac tcaatctaaa atttcattag gtgcagcttt tatatcaggc gtgattggaa
     8881 tatggatggc ttatgtcggt tgcggggttt gggctttagt ttggcaaact ctcttaaata
     8941 gtataatttt gacaattttg ttttactgtt tagttcattg gaaaccttta catactttct
     9001 ccaaaagttc ttttgaaaga ttattcaatt tcggatctaa attattgatc tcaagtctta
     9061 tcaatacagt atatcgtaat ctgtatacca ttgtaatagg aaaaaagttt tctgttgtag
     9121 agcttggtta ctatacaaga gcagaacaat ttgctatttt tccttccaat aatttaaatg
     9181 ctttagtttc tagagtagcg tatcctattt taagttccat tcaagatgat gataaatgtt
     9241 taacaaacgc atatcgaaat tatatcagat tatcctcata tataattttt cctttaatgg
     9301 taggtttact tgttttggct aatcctatta ttagtctatt gttaacagat aaatggtctg
     9361 gggttgttat tcttttacag atattatgtt tggattggat gtttgatcat ttgagccaaa
     9421 ttaatttgaa tttattatgg gttaaaggaa gatctgatct gtcgttacgt cttgaaataa
     9481 taaaaaagac gattgctata ttcattcttt ttgtgtcaat tccatttggg cttgaggtga
     9541 tgtgttgggg tagagttatt tactctctga tagcgacata tttgaataca tattatacta
     9601 attctcttat tgatttgacc ttaaagttgc aagttaaaga tgtatttcca agtttaatac
     9661 tctctttcat aatggggggg atcgttttta tatgtatttc tttctttgaa actgatatag
     9721 taaaaattgt gattggatgt attactggga tgtccttcta tattttactt tcttttcttt
     9781 ttaagctaga ttcttttttt tgtattttaa cattgatcat taaaactaaa aacatagatg
     9841 aaaatattaa aaaagatttt tcaagtaata gtaaagataa ttaaccattg tgtgccagtt
     9901 gatagtagat cattgtattt tattcctcat cctaattgta gaacagataa atatgatatt
     9961 ataaattatt cgtcagataa tgttctcgtt ctgttaaatt atttgctaaa aaaagatagt
    10021 gctgaatatt ataaaatata tgttgaaatt tatgattctt ctcgtatttc agaatatcaa
    10081 gaatatattt atggcataaa tcctaatatt aggtgtactt ttttatgtgc atgtgttgga
    10141 cgttttttct ttaataaagt atcttttaag gatatgttgt atgccttttt ttgtttttgt
    10201 agagcaagta aatgttttac agctactttt tattatgatt tttcatttaa aaaacgctct
    10261 caacagatta tttgtttggg gtattatact ccattcaaag atgattatca tatgggagat
    10321 cattcttatg ataaatttcg taatacaaca tgtaactcat ttgattactc tattgctact
    10381 tcttgtttaa gtgctagaat aatttcaata gattgtggaa tctcatatga taaattcaaa
    10441 gtcttaggat ttcccagaaa tgatttgttg atatcgaaaa ataattgcaa tgttattaaa
    10501 agagaaattt cgaaatttgc gggatatgat gtaactaaat atatagttta tactccaact
    10561 tttcgtgatt atgagactgt tactgaaggt aatttgcgtt caatactcgg atatgttgat
    10621 tgtgatttgt tgaagttatc gaaaatacta ttgaagttta atgcggcttt aattcttaaa
    10681 ttacatcctt tgcagaataa aacagtctta aaaaaagatt tacccaaagg tatacttgtt
    10741 tttgaacaaa catataaata tggattgtat gatcttttgt cattttcaga tggaatgatt
    10801 actgattata cttctaccta ttttgatttt ttattggtaa ataagccagt catatttaat
    10861 ttctacgata ttgaagaata tcgtagagta agaggtttct catttgagcc aatagaattt
    10921 ttttgtgcag gtgatattgt ttacaattat aatgaattga tagatgctgt gatgggactt
    10981 ctggctggga aagatattca tgctgaacat cgacgtcata tttctttatt gatgaatcaa
    11041 tttcaagatg ataattcaac aaagagaata tgtgacatat ttttaaatga aatataataa
    11101 ataaaatgaa ttatgcattt gtggtgcagg cacgtttagg ttctacacgt ttgcctggaa
    11161 aaatattgaa acctttctat ggtaatcaat cgattcttga cttaatggtt cataagcttt
    11221 ctgctatatc gaatattcca gtaattattg ctacaacaaa ttctgttatc aatgaaccta
    11281 ttgaaaagaa ggcacttgca ttaggggtaa agtgcttcag aggtgaggag aatgatgttt
    11341 taaaacgatt cattgatgtt gctgaatatt ttgatataca gggtatattc cgaatatgtt
    11401 ctgataatcc atttttagat gtacatgcgg caaggcaatt ggtcgaaata gcaatgaaat
    11461 cttgtaacga ttatataagt tttgatattg atggtactcc atcaattaaa actcatttcg
    11521 gtttttgggg agaatttgta acgcttgatg cgctgaagcg agttatagga tttactgatg
    11581 atttattgta tcgtgaacat gttactaatt atatatatag tcatcctgaa ctttttaata
    11641 ttcaatggat ttcaggatct ccagtcgtgt caaaacatca taatattcga ctcacgattg
    11701 atacgttaga agatttttct gtagcacaga gaatatatag ggatttacaa gaaaaaagag
    11761 tggaaatatc gatagaagtg attgtagact atgttcgaag acatgcagaa tacattcaac
    11821 tgatgaaaca acaaataaaa aaaaattcta aataatgaag aatacttata ttattggtga
    11881 aatagggcag aatcataatg gttctgttga cttggctaag ttgattattg aattaatctc
    11941 acgacctgta catgaggatg tttttggtat ggatttcatg ccaatgaatg ctgttaaaat
    12001 gactaaaaga gatttatcag aagaattggc tgtttctcaa atgaatcaaa tatatgacaa
    12061 tcctaattct tttgggcgta cttatggtga acatcgtgct tttcttgagc ttgatgatca
    12121 agcgcatttt gagatttata aatatgctaa gtcattagga ttagatttta tcgagacgtt
    12181 atgtgccaaa ggatgtctgt ctttgcttaa actgttcaca ccggataggc taaaagttgc
    12241 tagtcgtgat ttgactaact taccattgct tgaagcatta gcagaaactc atattcctat
    12301 tatattatcg acaggaatgg ctggtcaaag agaacttgac aatgcattag atgtgataac
    12361 gagatatcat agtaatatag ctattctaca ttgtgtatct cagtatccaa ctcatccaaa
    12421 taatttgaat ctacgtacaa taacatattt gaagaagcat tacaataagt ttgagatagg
    12481 tttttctgat catacaatag gtatttctgc tgctacagct gctgtagcga tgggagcgga
    12541 aattatagaa aagcatgtaa caattgatcg gcatatgaaa ggaacagacc agcttggctc
    12601 tttaggtcca gatggggtta atcgtatgat tcgagatatt cgcatagcag agtgttggct
    12661 tggtactgaa gatctttata tagaaaaagg ggtggagaag tctaagataa aacttgaacg
    12721 ttctattgcc actcgaaaat atattccagc aggtagtatt attcaagagt cggacattca
    12781 tttactgagt cctggtgatg gttataaatg gatagataaa aaaaatgtaa ttggtcattt
    12841 tgctaaacaa gatatatcag cgaatgaaat aatatatcct gattttattg aatagatata
    12901 ttcctactgc aacttgtatt acggtataga gtactgcctg ctataagcta agtagtgatt
    12961 aataaataag ggtaaaatac taaaaaaatg aaagagataa agcttatact tacagatatt
    13021 gatggcgttt ggactgatgg cggaatgttt tatgatc
//
