## Fri May  2 00:27:02 2025
## emapper-2.1.12
## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_003458645.1/GCA_003458645.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_003458645.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_003458645.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
IGHDCBEA_00001	1046629.Ssal_01480	2.75e-170	477.0	COG0596@1|root,COG0596@2|Bacteria,1UMWY@1239|Firmicutes	1239|Firmicutes	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
IGHDCBEA_00002	1046629.Ssal_01490	6.47e-76	226.0	2DVV7@1|root,33XC5@2|Bacteria	2|Bacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
IGHDCBEA_00003	1046629.Ssal_01491	3.78e-58	180.0	2FAP6@1|root,342WU@2|Bacteria,1VX2X@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00004	638301.HMPREF0444_1312	3.91e-124	354.0	2DBDH@1|root,2Z8KQ@2|Bacteria,1V2YZ@1239|Firmicutes,4HK4W@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00005	411489.CLOL250_02700	1.13e-85	254.0	COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,24HK5@186801|Clostridia,36JMS@31979|Clostridiaceae	186801|Clostridia	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
IGHDCBEA_00006	936596.HMPREF1495_1854	2.75e-10	58.5	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
IGHDCBEA_00007	1354300.AUQY01000005_gene87	1.85e-69	209.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,22IPD@1570339|Peptoniphilaceae	186801|Clostridia	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
IGHDCBEA_00008	1095727.HMPREF1117_0770	5.82e-165	462.0	COG1266@1|root,COG1266@2|Bacteria,1V416@1239|Firmicutes,4HRGM@91061|Bacilli	91061|Bacilli	S	CAAX amino terminal protease family protein	lyrA	-	-	-	-	-	-	-	-	-	-	-	Abi
IGHDCBEA_00009	1316408.HSISM1_1085	4.31e-134	381.0	COG4335@1|root,COG4335@2|Bacteria,1TPRQ@1239|Firmicutes	1239|Firmicutes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
IGHDCBEA_00010	888833.HMPREF9421_1199	4.14e-198	550.0	COG3173@1|root,COG3173@2|Bacteria,1U4B2@1239|Firmicutes,4HG90@91061|Bacilli	91061|Bacilli	KLT	Aminoglycoside phosphotransferase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	APH
IGHDCBEA_00011	1035189.HMPREF9954_1212	4.4e-69	209.0	COG1725@1|root,COG1725@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
IGHDCBEA_00012	1035189.HMPREF9954_1211	6.65e-39	130.0	2E06M@1|root,32VUK@2|Bacteria,1VAMX@1239|Firmicutes,4HYCN@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
IGHDCBEA_00013	1095727.HMPREF1117_0768	0.0	877.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,4HDGF@91061|Bacilli	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
IGHDCBEA_00014	1035189.HMPREF9954_1207	1.56e-165	463.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,43F8M@68892|Streptococcus infantis	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_00015	1035189.HMPREF9954_1206	9.85e-140	395.0	COG1309@1|root,COG1309@2|Bacteria,1TPXF@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IGHDCBEA_00016	585204.SMSK597_1866	5.96e-119	344.0	COG2801@1|root,COG2801@2|Bacteria,1UVZW@1239|Firmicutes,4I47Y@91061|Bacilli,2TQDQ@28037|Streptococcus mitis	91061|Bacilli	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
IGHDCBEA_00017	585204.SMSK597_1867	1.49e-59	184.0	COG2963@1|root,COG2963@2|Bacteria,1U4Y6@1239|Firmicutes,4IEPQ@91061|Bacilli,2TQEJ@28037|Streptococcus mitis	91061|Bacilli	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00018	1111134.HMPREF1253_0849	1.32e-126	362.0	COG0500@1|root,COG2226@2|Bacteria,1TR4Y@1239|Firmicutes,24DHJ@186801|Clostridia,22G9T@1570339|Peptoniphilaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
IGHDCBEA_00019	1046629.Ssal_01495	0.0	870.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
IGHDCBEA_00020	1046629.Ssal_01496	1.28e-126	360.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	mip	-	-	-	-	-	-	-	-	-	-	-	CMD
IGHDCBEA_00021	1046629.Ssal_01497	3.83e-257	704.0	COG1960@1|root,COG1960@2|Bacteria,1UYHK@1239|Firmicutes,4HCT5@91061|Bacilli	91061|Bacilli	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_N
IGHDCBEA_00022	904306.HMPREF9192_1383	9.15e-196	546.0	COG1275@1|root,COG1275@2|Bacteria,1UYTE@1239|Firmicutes,4HGBI@91061|Bacilli	91061|Bacilli	P	C4-dicarboxylate transporter malic acid transport	ydiA	-	-	ko:K11041	ko05150,map05150	-	-	-	ko00000,ko00001,ko02042	2.A.16	-	-	SLAC1
IGHDCBEA_00023	904306.HMPREF9192_1382	0.0	870.0	COG1316@1|root,COG1316@2|Bacteria,1TSWQ@1239|Firmicutes,4HE66@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	msrR	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IGHDCBEA_00024	1046629.Ssal_01508	2.42e-197	546.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli	91061|Bacilli	E	Prephenate dehydratase	pheA	GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU27900	ACT,PDT
IGHDCBEA_00025	904306.HMPREF9192_1380	4.42e-111	319.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli	91061|Bacilli	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
IGHDCBEA_00026	1046629.Ssal_01510	1.77e-299	818.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
IGHDCBEA_00027	1046629.Ssal_01511	3.48e-218	603.0	COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli	91061|Bacilli	C	Belongs to the LDH MDH superfamily	hicD2	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
IGHDCBEA_00028	1046629.Ssal_01512	2.99e-71	214.0	COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HPJM@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0342 family	XK26_04240	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
IGHDCBEA_00029	1046629.Ssal_01513	6.41e-264	723.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli	91061|Bacilli	E	prephenate dehydrogenase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22610	ACT,PDH
IGHDCBEA_00030	904306.HMPREF9192_1375	1.83e-279	764.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli	91061|Bacilli	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
IGHDCBEA_00031	1046629.Ssal_01515	7.17e-258	706.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli	91061|Bacilli	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
IGHDCBEA_00032	904306.HMPREF9192_1373	3.19e-203	562.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
IGHDCBEA_00033	1046629.Ssal_01517	2.48e-152	429.0	COG0710@1|root,COG0710@2|Bacteria,1VHVX@1239|Firmicutes,4IPJP@91061|Bacilli	91061|Bacilli	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
IGHDCBEA_00034	1046629.Ssal_01518	1.89e-276	756.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli	91061|Bacilli	J	Methyltransferase	ywbD	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
IGHDCBEA_00035	1046629.Ssal_01519	0.0	1388.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli	91061|Bacilli	M	Belongs to the LTA synthase family	ltaS	GO:0005575,GO:0005576	2.7.8.20	ko:K19005	ko00561,ko01100,map00561,map01100	-	R05081,R10849	RC00017	ko00000,ko00001,ko01000	-	-	-	Sulfatase
IGHDCBEA_00036	1046629.Ssal_01520	1.1e-34	118.0	2FKS5@1|root,34CCP@2|Bacteria,1W67C@1239|Firmicutes	1239|Firmicutes	-	-	WQ51_00785	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00037	1046629.Ssal_01521	6.13e-315	857.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli	91061|Bacilli	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
IGHDCBEA_00038	1046629.Ssal_01522	1.2e-100	292.0	COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1694)	XK27_05190	-	-	-	-	-	-	-	-	-	-	-	DUF1694
IGHDCBEA_00039	1046629.Ssal_01524	6.56e-253	695.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes	1239|Firmicutes	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
IGHDCBEA_00040	1046629.Ssal_01525	1.27e-239	661.0	COG2315@1|root,COG2315@2|Bacteria,1V4K7@1239|Firmicutes,4HP2K@91061|Bacilli	91061|Bacilli	S	YjbR	XK27_07735	-	-	-	-	-	-	-	-	-	-	-	EVE,YjbR
IGHDCBEA_00041	1046629.Ssal_01526	4.5e-234	644.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli	91061|Bacilli	K	Catabolite control protein A	ccpA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IGHDCBEA_00042	1046629.Ssal_01528	4.73e-266	728.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli	91061|Bacilli	E	Belongs to the peptidase M24B family	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
IGHDCBEA_00043	1046629.Ssal_01529	1.6e-82	244.0	COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli	91061|Bacilli	J	RNA binding protein, contains ribosomal protein S1 domain	yugI	-	-	ko:K07570	-	-	-	-	ko00000	-	-	-	S1
IGHDCBEA_00044	322159.STER_0676	0.0	924.0	COG0561@1|root,COG0652@1|root,COG0561@2|Bacteria,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli	91061|Bacilli	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Hydrolase_3,Pro_isomerase
IGHDCBEA_00045	264199.stu0626	5.69e-105	303.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli	91061|Bacilli	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
IGHDCBEA_00046	1046629.Ssal_01532	0.0	1569.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli	91061|Bacilli	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
IGHDCBEA_00047	904306.HMPREF9192_1354	1.06e-44	145.0	COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli	91061|Bacilli	U	Preprotein translocase subunit SecG	secG	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
IGHDCBEA_00048	1046629.Ssal_01534	8.43e-281	769.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli	91061|Bacilli	EGP	Major Facilitator	pmrA	-	-	ko:K08161	-	-	-	-	ko00000,ko02000	2.A.1.2.20	-	-	MFS_1,MFS_1_like,Sugar_tr
IGHDCBEA_00049	1046629.Ssal_01535	4.67e-125	357.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli	91061|Bacilli	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08510	CoaE
IGHDCBEA_00050	1046629.Ssal_01536	3.41e-192	533.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
IGHDCBEA_00051	1046629.Ssal_01539	6.73e-212	585.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli	91061|Bacilli	M	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
IGHDCBEA_00052	1046629.Ssal_01540	7.01e-85	251.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli	91061|Bacilli	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07900	DAGK_prokar
IGHDCBEA_00053	1046629.Ssal_01541	1.31e-113	326.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
IGHDCBEA_00054	1046629.Ssal_01542	5.63e-192	533.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli	91061|Bacilli	K	antiterminator	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
IGHDCBEA_00055	1046629.Ssal_01543	1.85e-136	386.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
IGHDCBEA_00056	1046629.Ssal_01544	0.0	1322.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli	91061|Bacilli	M	penicillin-binding protein	pbp2b	-	-	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
IGHDCBEA_00057	1046629.Ssal_01545	1.61e-188	525.0	COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli	91061|Bacilli	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
IGHDCBEA_00058	1046629.Ssal_01546	9.93e-201	556.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli	91061|Bacilli	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
IGHDCBEA_00059	1046629.Ssal_01547	1.3e-193	536.0	COG2267@1|root,COG2267@2|Bacteria,1V37Y@1239|Firmicutes,4ITDD@91061|Bacilli	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
IGHDCBEA_00060	759913.SDSE_1600	2.42e-12	61.2	2DJ8A@1|root,304YV@2|Bacteria,1TXF8@1239|Firmicutes,4I6DK@91061|Bacilli,1MA5P@119603|Streptococcus dysgalactiae group	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00061	1046629.Ssal_01549	0.0	1366.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli	91061|Bacilli	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	iSB619.SA_RS13395	FeoB_C,FeoB_N,Gate
IGHDCBEA_00062	1046629.Ssal_01550	1.49e-102	297.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4HPFS@91061|Bacilli	91061|Bacilli	P	FeoA domain protein	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
IGHDCBEA_00063	1046629.Ssal_01552	1.09e-169	474.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IGHDCBEA_00064	1046629.Ssal_01553	2.2e-151	426.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4IQKK@91061|Bacilli	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IGHDCBEA_00065	1046629.Ssal_01554	3.31e-47	151.0	COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	ykuJ	-	-	-	-	-	-	-	-	-	-	-	DUF1797
IGHDCBEA_00066	1046629.Ssal_01556	1.51e-233	642.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli	91061|Bacilli	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
IGHDCBEA_00067	904306.HMPREF9192_1333	0.0	1399.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03697	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,UVR
IGHDCBEA_00068	1046629.Ssal_01558	3.73e-109	313.0	COG0494@1|root,COG0494@2|Bacteria,1VH6Q@1239|Firmicutes,4HQVJ@91061|Bacilli	91061|Bacilli	L	Belongs to the Nudix hydrolase family	XK27_09440	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IGHDCBEA_00069	1046629.Ssal_01559	2.23e-65	199.0	2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF1827)	XK27_09445	-	-	-	-	-	-	-	-	-	-	-	DUF1827
IGHDCBEA_00070	1046629.Ssal_01560	1.38e-226	624.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HDXF@91061|Bacilli	91061|Bacilli	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
IGHDCBEA_00071	1046629.Ssal_01562	2.37e-151	426.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
IGHDCBEA_00072	1046629.Ssal_01563	5.27e-140	396.0	2DMIQ@1|root,32RV1@2|Bacteria,1VGN9@1239|Firmicutes,4I0DZ@91061|Bacilli	91061|Bacilli	S	Domain of Unknown Function with PDB structure (DUF3862)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3862
IGHDCBEA_00075	1046629.Ssal_01564	9.51e-268	736.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli	91061|Bacilli	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
IGHDCBEA_00078	1035187.HMPREF9959_0525	3.44e-22	88.2	29N96@1|root,30971@2|Bacteria,1U4J6@1239|Firmicutes,4IEAX@91061|Bacilli,2TPZ6@28037|Streptococcus mitis	91061|Bacilli	S	Protein of unknown function (DUF2969)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2969
IGHDCBEA_00079	1046629.Ssal_01567	7.12e-255	697.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli	91061|Bacilli	E	Aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU38550	Aminotran_4
IGHDCBEA_00080	904306.HMPREF9192_1319	0.0	1581.0	COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli	91061|Bacilli	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
IGHDCBEA_00083	1046629.Ssal_01572	0.0	1248.0	COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli	91061|Bacilli	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
IGHDCBEA_00084	1046629.Ssal_01573	3.01e-138	392.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli	91061|Bacilli	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
IGHDCBEA_00085	759913.SDSE_1678	2.18e-19	84.7	2DJ7H@1|root,304X7@2|Bacteria,1TXCP@1239|Firmicutes,4I6AH@91061|Bacilli,1M9TG@119603|Streptococcus dysgalactiae group	91061|Bacilli	L	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5
IGHDCBEA_00086	1035184.HMPREF1042_0385	3.14e-42	139.0	2BXCI@1|root,346RD@2|Bacteria,1VYRT@1239|Firmicutes,4HYPP@91061|Bacilli,42DR8@671232|Streptococcus anginosus group	91061|Bacilli	S	Domain of unknown function (DUF1912)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1912
IGHDCBEA_00087	1046629.Ssal_01576	1.21e-218	604.0	COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli	91061|Bacilli	H	Homocysteine	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
IGHDCBEA_00088	1046629.Ssal_01577	0.0	875.0	COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes	1239|Firmicutes	E	amino acid	lysP	-	-	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.10	-	iHN637.CLJU_RS13850	AA_permease
IGHDCBEA_00089	435842.HMPREF0848_00217	7.88e-143	402.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
IGHDCBEA_00090	1046629.Ssal_01579	8.89e-288	786.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
IGHDCBEA_00091	435842.HMPREF0848_00215	2.97e-30	107.0	2DFKW@1|root,2ZS8U@2|Bacteria,1W5G0@1239|Firmicutes,4HZFD@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00092	904306.HMPREF9192_1309	7.88e-116	332.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli	91061|Bacilli	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
IGHDCBEA_00093	1046629.Ssal_01582	9.98e-212	584.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4HI1C@91061|Bacilli	91061|Bacilli	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
IGHDCBEA_00094	1046629.Ssal_01584	2.45e-268	736.0	COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli	91061|Bacilli	I	synthase	mvaS	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
IGHDCBEA_00095	1046629.Ssal_01585	8.17e-285	780.0	COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli	91061|Bacilli	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88,2.3.1.9	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177,R02081	RC00004,RC00326,RC00644	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	HMG-CoA_red
IGHDCBEA_00096	1046629.Ssal_01586	1.08e-102	297.0	COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes	1239|Firmicutes	K	hmm pf08876	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
IGHDCBEA_00097	435842.HMPREF0848_00209	8.29e-151	425.0	COG1272@1|root,COG1272@2|Bacteria,1TTA5@1239|Firmicutes,4HDYT@91061|Bacilli	91061|Bacilli	K	protein, Hemolysin III	hly-III	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
IGHDCBEA_00098	1046629.Ssal_01589	1.64e-39	130.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli	91061|Bacilli	KT	PspC domain protein	pspC	-	-	-	-	-	-	-	-	-	-	-	PspC
IGHDCBEA_00099	904306.HMPREF9192_1302	1.87e-247	680.0	2DQ82@1|root,3357U@2|Bacteria,1VFZ3@1239|Firmicutes,4HNXV@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3114
IGHDCBEA_00100	1046629.Ssal_01591	3.7e-178	501.0	COG0596@1|root,COG0596@2|Bacteria,1V202@1239|Firmicutes,4HJ0U@91061|Bacilli	91061|Bacilli	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	GO:0003674,GO:0003824,GO:0016787	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
IGHDCBEA_00101	1046629.Ssal_01592	0.0	1299.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
IGHDCBEA_00102	1046629.Ssal_01594	0.0	865.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase, group 1 family protein	pimB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
IGHDCBEA_00103	1046629.Ssal_01595	2.44e-242	665.0	COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HBKA@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase, group 1 family protein	dgs	-	2.4.1.208	ko:K13677	ko00561,ko01100,map00561,map01100	-	R05164	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
IGHDCBEA_00104	1046629.Ssal_01596	0.0	1754.0	COG3156@1|root,COG4932@1|root,COG3156@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cna_B,Collagen_bind,FctA,Gram_pos_anchor,MucBP,SdrD_B,T2SSK,YSIRK_signal
IGHDCBEA_00105	1046629.Ssal_01597	6.02e-151	426.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli	91061|Bacilli	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
IGHDCBEA_00106	1046629.Ssal_01598	1.26e-42	140.0	2DC3Q@1|root,2ZCSA@2|Bacteria,1W5SW@1239|Firmicutes,4I23E@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00107	1046629.Ssal_01599	2.48e-124	354.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli	91061|Bacilli	L	AdP-ribose pyrophosphatase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
IGHDCBEA_00108	1046629.Ssal_01601	0.0	890.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
IGHDCBEA_00109	1046629.Ssal_01602	0.0	1665.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli	91061|Bacilli	P	COG0474 Cation transport ATPase	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
IGHDCBEA_00110	1046629.Ssal_01605	6.17e-237	652.0	COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli	91061|Bacilli	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
IGHDCBEA_00111	1046629.Ssal_01606	7.64e-225	621.0	COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HWXG@91061|Bacilli	91061|Bacilli	I	phosphomevalonate kinase	mvaK2	-	2.7.4.2	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R03245	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
IGHDCBEA_00112	1046629.Ssal_01607	3.78e-221	610.0	COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli	91061|Bacilli	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
IGHDCBEA_00113	1046629.Ssal_01608	6.85e-197	547.0	COG1577@1|root,COG1577@2|Bacteria,1TPVW@1239|Firmicutes,4IRCB@91061|Bacilli	91061|Bacilli	I	mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
IGHDCBEA_00114	904306.HMPREF9192_1284	2.66e-126	360.0	COG3575@1|root,COG3575@2|Bacteria,1V1YD@1239|Firmicutes,4HGK6@91061|Bacilli	91061|Bacilli	J	protein conserved in bacteria	-	-	-	ko:K09962	-	-	-	-	ko00000	-	-	-	NTP_transf_6
IGHDCBEA_00115	1316408.HSISM1_1405	1.41e-114	344.0	2BZD2@1|root,2Z88S@2|Bacteria,1UZZH@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00116	1316408.HSISM1_1406	3.07e-107	315.0	COG1131@1|root,COG1131@2|Bacteria,1TRG3@1239|Firmicutes,4HUWJ@91061|Bacilli	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_00117	1123318.KB904614_gene1135	7.57e-106	316.0	COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HC2C@91061|Bacilli	91061|Bacilli	K	Transcriptional activator, Rgg GadR MutR family	rgg	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IGHDCBEA_00118	435842.HMPREF0848_00188	2.8e-313	853.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli	91061|Bacilli	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
IGHDCBEA_00119	1046629.Ssal_01611	7.39e-155	438.0	COG2021@1|root,COG2021@2|Bacteria,1UUC7@1239|Firmicutes	1239|Firmicutes	E	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
IGHDCBEA_00122	1046629.Ssal_01614	3.36e-250	688.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli	91061|Bacilli	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
IGHDCBEA_00123	1046629.Ssal_01616	2.99e-270	740.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli	91061|Bacilli	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	hipO2	-	-	ko:K01436,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
IGHDCBEA_00124	264199.stu0553	3.96e-165	462.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IGHDCBEA_00125	904306.HMPREF9192_1280	5.13e-146	413.0	COG1814@1|root,COG1814@2|Bacteria,1V6KW@1239|Firmicutes,4IPIC@91061|Bacilli	91061|Bacilli	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
IGHDCBEA_00126	264199.stu0551	1e-171	480.0	COG2820@1|root,COG2820@2|Bacteria,1V6T2@1239|Firmicutes,4HCSE@91061|Bacilli	91061|Bacilli	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
IGHDCBEA_00127	888049.HMPREF8578_1766	2.12e-25	102.0	29QF9@1|root,30BEN@2|Bacteria,1TWW2@1239|Firmicutes,4I5QM@91061|Bacilli,1WPHP@1303|Streptococcus oralis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00128	264199.stu0549	3.55e-39	131.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli	91061|Bacilli	K	Transcriptional	XK27_00085	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
IGHDCBEA_00129	1046629.Ssal_01622	3.36e-251	687.0	COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0176 family	ybfQ	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
IGHDCBEA_00130	1046629.Ssal_01623	2.22e-55	173.0	COG4898@1|root,COG4898@2|Bacteria,1V6U6@1239|Firmicutes,4HH1D@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
IGHDCBEA_00131	1046629.Ssal_01624	1e-155	438.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli	91061|Bacilli	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
IGHDCBEA_00132	435842.HMPREF0848_00175	1.38e-251	690.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli	91061|Bacilli	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
IGHDCBEA_00133	1046629.Ssal_01626	0.0	1115.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	lmrA	-	-	ko:K06147,ko:K18888	ko02010,map02010	M00706	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_00134	435842.HMPREF0848_00173	0.0	1085.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	msbA_1	-	-	ko:K18887	ko02010,map02010	M00706	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
IGHDCBEA_00135	1122149.BACN01000009_gene1237	7.37e-73	231.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HDPG@91061|Bacilli,3FC6P@33958|Lactobacillaceae	91061|Bacilli	K	LysR substrate binding domain protein	rlrB	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IGHDCBEA_00136	1046629.Ssal_01630	0.0	973.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli	91061|Bacilli	M	Belongs to the BCCT transporter (TC 2.A.15) family	opuD	GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0008150,GO:0008324,GO:0008519,GO:0009266,GO:0009409,GO:0009628,GO:0015075,GO:0015101,GO:0015199,GO:0015651,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0022857,GO:0031460,GO:0034220,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072337,GO:0072349,GO:0072488,GO:0098655	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
IGHDCBEA_00137	1123318.KB904587_gene642	5.72e-118	339.0	COG5340@1|root,COG5340@2|Bacteria,1V3JU@1239|Firmicutes,4HMVW@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
IGHDCBEA_00138	1123315.AUIP01000021_gene2248	3.44e-122	379.0	COG3942@1|root,COG3942@2|Bacteria,1VPFZ@1239|Firmicutes,4HFGV@91061|Bacilli	91061|Bacilli	M	CHAP domain protein	XK27_00530	-	-	-	-	-	-	-	-	-	-	-	CHAP,Peptidase_M23
IGHDCBEA_00140	1095726.HMPREF1116_0592	6.97e-242	669.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
IGHDCBEA_00142	699248.SRA_07801	1.07e-107	313.0	2D82H@1|root,32TQ8@2|Bacteria,1VDSV@1239|Firmicutes,4HSS8@91061|Bacilli	91061|Bacilli	S	Plasmid replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_2
IGHDCBEA_00143	1095738.HMPREF1047_1589	1.41e-59	192.0	2ERR9@1|root,304NZ@2|Bacteria,1TWYQ@1239|Firmicutes,4I5TN@91061|Bacilli,1WPXP@1303|Streptococcus oralis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00144	1123300.AUIN01000021_gene767	9.54e-228	630.0	COG1674@1|root,COG1674@2|Bacteria,1UZV0@1239|Firmicutes,4HCE6@91061|Bacilli	91061|Bacilli	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,FtsK_SpoIIIE
IGHDCBEA_00145	1095738.HMPREF1047_1591	7.34e-57	177.0	29QR3@1|root,30BQX@2|Bacteria,1TWYS@1239|Firmicutes,4I5TQ@91061|Bacilli,1WPXV@1303|Streptococcus oralis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00146	1227360.C176_17521	1.39e-35	143.0	2DWE2@1|root,33ZW2@2|Bacteria,1VY1Y@1239|Firmicutes,4HX5Y@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00148	211110.gbs1324	0.0	2027.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1UHWQ@1239|Firmicutes,4HCBT@91061|Bacilli	91061|Bacilli	LV	TaqI-like C-terminal specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
IGHDCBEA_00149	264199.stu0537	6.49e-65	199.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
IGHDCBEA_00150	1046629.Ssal_01633	8.41e-102	296.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli	91061|Bacilli	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
IGHDCBEA_00151	1046629.Ssal_01635	1.79e-268	737.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HF9U@91061|Bacilli	91061|Bacilli	V	permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IGHDCBEA_00152	1046629.Ssal_01636	6.54e-157	441.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli	91061|Bacilli	V	ABC transporter, ATP-binding protein	salX	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_00153	435842.HMPREF0848_00161	4.41e-249	689.0	COG0845@1|root,COG0845@2|Bacteria,1VBR9@1239|Firmicutes,4HG5X@91061|Bacilli	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
IGHDCBEA_00154	1046629.Ssal_01638	1.72e-165	464.0	COG4123@1|root,COG4123@2|Bacteria,1UJ4P@1239|Firmicutes,4IT17@91061|Bacilli	91061|Bacilli	S	Putative SAM-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	SAM_MT
IGHDCBEA_00155	1046629.Ssal_01639	0.0	2053.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli	91061|Bacilli	F	carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
IGHDCBEA_00156	1046629.Ssal_01640	7.9e-270	737.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli	91061|Bacilli	F	carbamoyl-phosphate synthetase glutamine chain	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
IGHDCBEA_00157	1046629.Ssal_01641	5.83e-222	612.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli	91061|Bacilli	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
IGHDCBEA_00158	1046629.Ssal_01642	4.94e-282	773.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli	91061|Bacilli	F	uracil Permease	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
IGHDCBEA_00159	1046629.Ssal_01644	1.45e-114	329.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli	91061|Bacilli	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
IGHDCBEA_00160	435842.HMPREF0848_00153	5.94e-207	573.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IGHDCBEA_00161	1046629.Ssal_01646	8.08e-100	290.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
IGHDCBEA_00162	1046629.Ssal_01647	2.35e-213	589.0	COG0583@1|root,COG0583@2|Bacteria,1V53I@1239|Firmicutes,4HIEU@91061|Bacilli	91061|Bacilli	K	transcriptional regulator (lysR family)	lysR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IGHDCBEA_00164	999425.HMPREF9186_00432	7.9e-57	178.0	290G9@1|root,2ZN5B@2|Bacteria,1W48Q@1239|Firmicutes,4I1UG@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00165	1046629.Ssal_01649	1.09e-89	265.0	COG1476@1|root,COG1476@2|Bacteria,1VPVM@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IGHDCBEA_00167	1046629.Ssal_01652	1.68e-177	494.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
IGHDCBEA_00168	1046629.Ssal_01653	0.0	1168.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli	91061|Bacilli	G	pts system	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
IGHDCBEA_00170	1046629.Ssal_01655	0.0	878.0	COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli	91061|Bacilli	E	permease	cycA	-	-	ko:K03293,ko:K11737	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.7	-	-	AA_permease
IGHDCBEA_00171	999425.HMPREF9186_01697	2.02e-52	165.0	COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli	91061|Bacilli	S	UPF0291 protein	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
IGHDCBEA_00172	1046629.Ssal_01657	0.0	1274.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli	91061|Bacilli	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
IGHDCBEA_00173	1046629.Ssal_01658	4.12e-225	619.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli	91061|Bacilli	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
IGHDCBEA_00174	1046629.Ssal_01659	1.07e-282	774.0	COG3949@1|root,COG3949@2|Bacteria,1U601@1239|Firmicutes,4HBYW@91061|Bacilli	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00175	1046629.Ssal_01660	1.65e-269	738.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
IGHDCBEA_00176	1046629.Ssal_01661	0.0	1021.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli	91061|Bacilli	P	COG1283 Na phosphate symporter	yjbB	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
IGHDCBEA_00177	1046629.Ssal_01662	4.02e-164	469.0	COG1705@1|root,COG1705@2|Bacteria	2|Bacteria	NU	amidase activity	-	-	3.4.17.14,3.5.1.28	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	-	-	-	Amidase_3,CHAP,CW_binding_1,GBS_Bsp-like,Glucosaminidase,SH3_5
IGHDCBEA_00178	1046629.Ssal_01663	2.46e-106	308.0	2E80M@1|root,332EU@2|Bacteria,1VJ8N@1239|Firmicutes,4HZSS@91061|Bacilli	91061|Bacilli	S	Bacterial inner membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV
IGHDCBEA_00179	1046629.Ssal_01664	2.45e-186	519.0	COG0561@1|root,COG0561@2|Bacteria,1VAFW@1239|Firmicutes,4HIFQ@91061|Bacilli	91061|Bacilli	S	Sucrose-6F-phosphate phosphohydrolase	XK27_04800	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IGHDCBEA_00180	1046629.Ssal_01666	3.77e-139	395.0	COG1705@1|root,COG1705@2|Bacteria	2|Bacteria	NU	amidase activity	mur1	-	3.4.17.14,3.5.1.28	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	-	-	-	GBS_Bsp-like,Glucosaminidase,Rod-binding
IGHDCBEA_00181	1046629.Ssal_01667	1.86e-70	213.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4HJ6Z@91061|Bacilli	91061|Bacilli	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
IGHDCBEA_00182	365659.smi_0683	4.12e-234	648.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli	91061|Bacilli	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
IGHDCBEA_00183	365659.smi_0683	2.1e-42	149.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli	91061|Bacilli	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
IGHDCBEA_00184	1046629.Ssal_01669	1.57e-200	556.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli	91061|Bacilli	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
IGHDCBEA_00185	1046629.Ssal_01670	2e-73	219.0	COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli	91061|Bacilli	L	Involved in initiation control of chromosome replication	yabA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	YabB
IGHDCBEA_00186	904306.HMPREF9192_0407	7.86e-175	489.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli	91061|Bacilli	S	stage 0 sporulation protein	yaaT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	PSP1
IGHDCBEA_00187	904306.HMPREF9192_0406	5.92e-202	560.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli	91061|Bacilli	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
IGHDCBEA_00188	1046629.Ssal_01673	3.28e-140	397.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
IGHDCBEA_00190	435842.HMPREF0848_00124	0.0	1280.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli	91061|Bacilli	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
IGHDCBEA_00191	1046629.Ssal_01675	7.68e-174	485.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli	91061|Bacilli	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
IGHDCBEA_00192	1046629.Ssal_01677	3.2e-285	779.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli	91061|Bacilli	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484	-	ko:K02358,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	3.A.1.1.16,3.A.1.1.2	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
IGHDCBEA_00193	435842.HMPREF0848_00121	1.6e-274	754.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli	91061|Bacilli	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
IGHDCBEA_00194	1046629.Ssal_01679	1.24e-89	263.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
IGHDCBEA_00195	1046629.Ssal_01680	0.0	909.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10965	ATP-synt_ab,ATP-synt_ab_N
IGHDCBEA_00196	1046629.Ssal_01681	6.4e-202	560.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSB619.SA_RS10970,iYO844.BSU36820	ATP-synt
IGHDCBEA_00197	904306.HMPREF9192_0397	0.0	963.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
IGHDCBEA_00198	1046629.Ssal_01683	1.23e-113	327.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKW1@91061|Bacilli	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
IGHDCBEA_00199	1046629.Ssal_01684	1.78e-102	298.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli	91061|Bacilli	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iYO844.BSU36850	ATP-synt_B
IGHDCBEA_00200	904306.HMPREF9192_0394	5.56e-154	434.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli	91061|Bacilli	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
IGHDCBEA_00201	1123298.KB904069_gene1213	5.88e-23	89.4	COG0636@1|root,2ZI0B@2|Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
IGHDCBEA_00202	1046629.Ssal_01687	2.75e-254	699.0	COG2348@1|root,COG2348@2|Bacteria,1V181@1239|Firmicutes,4HEVU@91061|Bacilli	91061|Bacilli	V	FemAB family	-	-	-	ko:K12554	ko00550,ko01100,map00550,map01100	-	R08780	RC00055,RC00064	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
IGHDCBEA_00204	1046629.Ssal_01688	5.68e-76	227.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli	91061|Bacilli	P	Belongs to the ArsC family	yusI	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
IGHDCBEA_00205	904306.HMPREF9192_0874	2.69e-92	272.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63,3.2.2.20	ko:K00567,ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
IGHDCBEA_00206	1046629.Ssal_00539	1.84e-281	769.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli	91061|Bacilli	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT_4
IGHDCBEA_00207	1046629.Ssal_00538	1.62e-135	383.0	COG1247@1|root,COG1247@2|Bacteria,1UIW7@1239|Firmicutes,4ISU9@91061|Bacilli	91061|Bacilli	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
IGHDCBEA_00208	1046629.Ssal_00537	1.47e-266	729.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli	91061|Bacilli	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
IGHDCBEA_00209	1046629.Ssal_00536	1.34e-206	572.0	COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli	91061|Bacilli	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
IGHDCBEA_00210	904306.HMPREF9192_0869	4.77e-93	271.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,4HJ7X@91061|Bacilli	91061|Bacilli	E	Lactoylglutathione lyase	gloA	-	4.4.1.5	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	M00491	R02530	RC00004,RC00740	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	Glyoxalase
IGHDCBEA_00211	1046629.Ssal_00531	4.79e-196	545.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli	91061|Bacilli	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
IGHDCBEA_00212	1046629.Ssal_00530	2.23e-261	715.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli	91061|Bacilli	P	spermidine putrescine ABC transporter	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iSB619.SA_RS05395	SBP_bac_8
IGHDCBEA_00213	1046629.Ssal_00529	3.07e-167	469.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli	91061|Bacilli	P	ABC-type spermidine putrescine transport system, permease component II	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
IGHDCBEA_00214	435842.HMPREF0848_01147	4.03e-179	500.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli	91061|Bacilli	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
IGHDCBEA_00215	904306.HMPREF9192_0862	9.28e-271	741.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli	91061|Bacilli	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K11072	ko02010,map02010	M00190,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.1	-	iSB619.SA_RS05380	ABC_tran,TOBE_2
IGHDCBEA_00216	1046629.Ssal_00526	3.23e-215	595.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
IGHDCBEA_00217	1046629.Ssal_00525	1.33e-105	305.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
IGHDCBEA_00218	1046629.Ssal_00524	3.53e-80	238.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli	91061|Bacilli	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
IGHDCBEA_00219	1046629.Ssal_00523	0.0	995.0	COG0366@1|root,COG0366@2|Bacteria,1TRKZ@1239|Firmicutes,4HC8C@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 13 family	amy	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF1939
IGHDCBEA_00220	1046629.Ssal_00522	8.69e-187	519.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli	91061|Bacilli	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
IGHDCBEA_00221	1046629.Ssal_00521	4.02e-129	367.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli	91061|Bacilli	F	gtp cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
IGHDCBEA_00222	1046629.Ssal_00520	0.0	1177.0	COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli	91061|Bacilli	E	amino acid	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
IGHDCBEA_00223	1046629.Ssal_00519	2.25e-303	827.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli	91061|Bacilli	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08370	Mur_ligase_C,Mur_ligase_M
IGHDCBEA_00224	1046629.Ssal_00518	3.17e-50	159.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
IGHDCBEA_00225	1046629.Ssal_00517	1.87e-57	178.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
IGHDCBEA_00227	1046629.Ssal_00515	5.9e-255	703.0	COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4IQEW@91061|Bacilli	91061|Bacilli	T	GHKL domain	-	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5
IGHDCBEA_00228	1046629.Ssal_00514	2.67e-166	466.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	agrA	-	-	ko:K07707	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
IGHDCBEA_00229	1046629.Ssal_00513	1.55e-247	686.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
IGHDCBEA_00230	904306.HMPREF9192_0841	2.02e-214	591.0	COG0500@1|root,COG3615@1|root,COG0500@2|Bacteria,COG3615@2|Bacteria,1TSZK@1239|Firmicutes,4HJT1@91061|Bacilli	91061|Bacilli	PQ	tellurite resistance protein tehb	tehB	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	DUF1971,TehB
IGHDCBEA_00231	888833.HMPREF9421_1657	3.71e-15	82.0	2DMBI@1|root,32H42@2|Bacteria,1VFT3@1239|Firmicutes,4HK1A@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4767)	yjdB	-	-	-	-	-	-	-	-	-	-	-	DUF4767
IGHDCBEA_00232	1046629.Ssal_00510	8.32e-254	696.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	XK27_00915	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
IGHDCBEA_00234	1046629.Ssal_00508	2.43e-202	559.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli	91061|Bacilli	L	exodeoxyribonuclease III	xth	GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
IGHDCBEA_00235	1046629.Ssal_00507	1.36e-94	277.0	COG4708@1|root,COG4708@2|Bacteria,1V99E@1239|Firmicutes,4HXAN@91061|Bacilli	91061|Bacilli	S	QueT transporter	-	-	-	-	-	-	-	-	-	-	-	-	QueT
IGHDCBEA_00237	1046629.Ssal_00505	4.81e-227	626.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	yfjR	GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_DeoR,WYL
IGHDCBEA_00238	1046629.Ssal_00504	1.91e-237	653.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli	91061|Bacilli	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
IGHDCBEA_00239	1046629.Ssal_00503	0.0	1243.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
IGHDCBEA_00240	1046629.Ssal_00502	1.71e-111	321.0	COG4708@1|root,COG4708@2|Bacteria,1V22G@1239|Firmicutes,4HGG2@91061|Bacilli	91061|Bacilli	S	cog cog4708	ccl	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	QueT
IGHDCBEA_00241	1046629.Ssal_00501	3.3e-210	582.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli	91061|Bacilli	E	Belongs to the UPF0761 family	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
IGHDCBEA_00242	1046629.Ssal_00500	2.01e-211	583.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli	91061|Bacilli	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
IGHDCBEA_00243	1046629.Ssal_00499	4.6e-290	794.0	COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli	91061|Bacilli	K	transcriptional regulator containing CBS domains	ytoI	-	-	-	-	-	-	-	-	-	-	-	4HBT,CBS,DRTGG,GntR,HTH_24
IGHDCBEA_00244	1046629.Ssal_00498	2.79e-125	357.0	COG1670@1|root,COG1670@2|Bacteria,1V576@1239|Firmicutes,4HH6U@91061|Bacilli	91061|Bacilli	J	Acetyltransferase GNAT Family	XK27_07830	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
IGHDCBEA_00245	1046629.Ssal_00497	1.34e-295	807.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli	91061|Bacilli	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU37100	EPSP_synthase
IGHDCBEA_00246	1046629.Ssal_00495	0.0	1389.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
IGHDCBEA_00247	1046629.Ssal_00493	5.32e-132	378.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli	91061|Bacilli	L	COG1555 DNA uptake protein and related DNA-binding proteins	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
IGHDCBEA_00248	1046629.Ssal_00492	5.9e-182	506.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli	91061|Bacilli	I	Acyltransferase	plsC	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
IGHDCBEA_00249	1046629.Ssal_00491	8.5e-218	602.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli	91061|Bacilli	G	deacetylase	nodB3	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
IGHDCBEA_00250	1046629.Ssal_00490	2.49e-180	502.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli	91061|Bacilli	L	Methyltransferase	yabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.223	ko:K07461,ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GIY-YIG,MTS
IGHDCBEA_00251	264199.stu1567	3.97e-54	169.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli	91061|Bacilli	L	endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
IGHDCBEA_00252	1046629.Ssal_00488	0.0	959.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli	91061|Bacilli	JKL	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity	cshA	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
IGHDCBEA_00253	1046629.Ssal_00487	3.84e-203	563.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HCQ6@91061|Bacilli	91061|Bacilli	P	CorA-like protein	corA	-	-	-	-	-	-	-	-	-	-	-	CorA
IGHDCBEA_00254	1046629.Ssal_00486	1.07e-82	244.0	arCOG12631@1|root,3172B@2|Bacteria,1V77G@1239|Firmicutes,4HJ0W@91061|Bacilli	91061|Bacilli	S	Bacterial PH domain	yjqA	-	-	-	-	-	-	-	-	-	-	-	bPH_1
IGHDCBEA_00255	1046629.Ssal_00485	2.54e-126	360.0	COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli	91061|Bacilli	S	Thiamine transporter	thiT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
IGHDCBEA_00256	1046629.Ssal_00484	1.28e-194	541.0	COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HC2C@91061|Bacilli	91061|Bacilli	K	Transcriptional activator, Rgg GadR MutR family	rgg	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IGHDCBEA_00257	322159.STER_1531	3.25e-243	672.0	COG2211@1|root,COG2211@2|Bacteria,1TR4D@1239|Firmicutes,4HDCY@91061|Bacilli	91061|Bacilli	G	Permeases of the major facilitator superfamily	yjbB	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
IGHDCBEA_00258	1046629.Ssal_00481	0.0	1034.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli	91061|Bacilli	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
IGHDCBEA_00259	1046629.Ssal_00479	7.12e-150	422.0	COG5522@1|root,COG5522@2|Bacteria	2|Bacteria	S	Integral membrane protein (intg_mem_TP0381)	ywaF	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
IGHDCBEA_00260	1046629.Ssal_00478	0.0	877.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli	91061|Bacilli	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IGHDCBEA_00263	1046629.Ssal_00476	1.1e-198	551.0	COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HFBQ@91061|Bacilli	91061|Bacilli	ET	ABC transporter substrate-binding protein	cjaA	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IGHDCBEA_00264	1046629.Ssal_00475	3.8e-174	486.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HDK7@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IGHDCBEA_00265	1046629.Ssal_00474	1.13e-148	419.0	COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,4HGVA@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	glnP7	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IGHDCBEA_00266	1046629.Ssal_00473	2.02e-147	416.0	COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,4HGE1@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	glnP9	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IGHDCBEA_00267	1046629.Ssal_00472	1.94e-247	679.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli	91061|Bacilli	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
IGHDCBEA_00268	1046629.Ssal_00471	5.6e-42	138.0	COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,4HR1Z@91061|Bacilli	91061|Bacilli	P	Heavy metal-associated domain protein	copZ	-	-	-	-	-	-	-	-	-	-	-	HMA
IGHDCBEA_00269	904306.HMPREF9192_0801	0.0	1325.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli	91061|Bacilli	P	P-type ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
IGHDCBEA_00270	435842.HMPREF0848_01207	1.68e-94	276.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	copY	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
IGHDCBEA_00271	1046629.Ssal_00467	1.37e-223	621.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
IGHDCBEA_00272	1046629.Ssal_00465	3.54e-183	509.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli	91061|Bacilli	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
IGHDCBEA_00273	1046629.Ssal_00464	3.5e-291	795.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli	91061|Bacilli	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22640	PALP
IGHDCBEA_00274	904306.HMPREF9192_0790	2.17e-128	365.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HK18@91061|Bacilli	91061|Bacilli	E	belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
IGHDCBEA_00275	1046629.Ssal_00461	6.26e-170	476.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HG9K@91061|Bacilli	91061|Bacilli	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
IGHDCBEA_00276	904306.HMPREF9192_0788	8.62e-228	629.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli	91061|Bacilli	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
IGHDCBEA_00277	1046629.Ssal_00458	7.09e-136	384.0	COG0512@1|root,COG0512@2|Bacteria,1V4RM@1239|Firmicutes,4HHD8@91061|Bacilli	91061|Bacilli	EH	anthranilate	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
IGHDCBEA_00278	1046629.Ssal_00457	0.0	887.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli	91061|Bacilli	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
IGHDCBEA_00279	1046629.Ssal_00456	2.51e-55	173.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	MA20_20425	-	2.5.1.19,4.2.1.10,4.2.99.21,5.4.99.5	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R03084,R03460,R06602	RC00350,RC00848,RC01549,RC02148,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
IGHDCBEA_00280	1046629.Ssal_00455	4.32e-155	435.0	COG1136@1|root,COG1136@2|Bacteria,1V3D1@1239|Firmicutes	1239|Firmicutes	V	ABC transporter	XK27_10210	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_00281	435842.HMPREF0848_01217	0.0	1240.0	COG4652@1|root,COG4652@2|Bacteria,1V0A8@1239|Firmicutes,4HI0H@91061|Bacilli	91061|Bacilli	S	bacteriocin-associated integral membrane protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DUF1430
IGHDCBEA_00282	585202.SMSK321_1211	7.36e-27	101.0	29UVG@1|root,30G7Y@2|Bacteria,1UFEG@1239|Firmicutes,4IEP3@91061|Bacilli,2TQDX@28037|Streptococcus mitis	91061|Bacilli	S	Bacteriocin (Lactococcin_972)	-	-	-	-	-	-	-	-	-	-	-	-	Lactococcin_972
IGHDCBEA_00283	1046629.Ssal_00451	1.32e-76	229.0	2C4MC@1|root,32RSW@2|Bacteria,1VCIA@1239|Firmicutes,4HKKA@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00284	1046629.Ssal_00450	0.0	1473.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli	91061|Bacilli	P	E1-E2 ATPase	ctpE	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
IGHDCBEA_00285	563038.HMPREF0851_01447	6.86e-56	180.0	2DEIC@1|root,2ZN3X@2|Bacteria,1W3A8@1239|Firmicutes,4HZMP@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00286	264199.stu1598	5.31e-59	182.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
IGHDCBEA_00288	1046629.Ssal_00444	4.76e-162	454.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_00289	1046629.Ssal_00443	0.0	1655.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli	91061|Bacilli	V	ABC transporter (Permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IGHDCBEA_00290	1046629.Ssal_00442	1.04e-169	474.0	COG0789@1|root,COG0789@2|Bacteria,1UZ0H@1239|Firmicutes,4HGGU@91061|Bacilli	91061|Bacilli	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
IGHDCBEA_00291	1046629.Ssal_00440	1.59e-136	386.0	COG0847@1|root,COG0847@2|Bacteria,1V8EQ@1239|Firmicutes,4HJYT@91061|Bacilli	91061|Bacilli	L	DNA polymerase III	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
IGHDCBEA_00292	1046629.Ssal_00439	5.18e-76	232.0	2EHT6@1|root,33BIW@2|Bacteria,1VNC1@1239|Firmicutes,4HRJ5@91061|Bacilli	91061|Bacilli	S	Protein of unknown function, DUF536	WQ51_02910	-	-	-	-	-	-	-	-	-	-	-	DUF536,HTH_11,HTH_24
IGHDCBEA_00293	904306.HMPREF9192_0775	1.81e-82	243.0	COG2151@1|root,COG2151@2|Bacteria,1VX9Z@1239|Firmicutes,4HXCM@91061|Bacilli	91061|Bacilli	S	cog cog2151	XK27_02560	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
IGHDCBEA_00294	1046629.Ssal_00436	0.0	1127.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli	91061|Bacilli	E	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
IGHDCBEA_00295	1046629.Ssal_00435	1.52e-285	780.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli	91061|Bacilli	S	Flavoprotein	ytfP	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
IGHDCBEA_00297	1046629.Ssal_00434	7.53e-157	439.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli	91061|Bacilli	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
IGHDCBEA_00298	1046629.Ssal_00433	2.95e-197	545.0	COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli	91061|Bacilli	M	Phosphotransferase	ytmP	-	-	-	-	-	-	-	-	-	-	-	APH
IGHDCBEA_00299	1046629.Ssal_00432	4.73e-220	610.0	COG4473@1|root,COG4473@2|Bacteria,1V9K7@1239|Firmicutes	1239|Firmicutes	U	Bacterial ABC transporter protein EcsB	XK27_05910	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	EcsB
IGHDCBEA_00300	1046629.Ssal_00431	4.12e-169	473.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_00301	435842.HMPREF0848_01246	1.45e-93	273.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli	91061|Bacilli	FG	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
IGHDCBEA_00305	1046629.Ssal_00427	1.98e-133	379.0	2AIHW@1|root,318ZT@2|Bacteria,1V92M@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
IGHDCBEA_00307	1046629.Ssal_00425	0.0	1340.0	COG0542@1|root,COG0542@2|Bacteria,1TRHP@1239|Firmicutes,4HAHZ@91061|Bacilli	91061|Bacilli	O	ATP-dependent Clp protease ATP-binding subunit	clpL	-	-	ko:K04086	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,UVR
IGHDCBEA_00308	1046629.Ssal_00423	6.01e-58	179.0	COG4115@1|root,COG4115@2|Bacteria,1VEN0@1239|Firmicutes,4HRVW@91061|Bacilli	91061|Bacilli	S	Addiction module toxin, Txe YoeB family	yoeB	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
IGHDCBEA_00309	1046629.Ssal_00422	6.54e-53	166.0	COG2161@1|root,COG2161@2|Bacteria,1VM12@1239|Firmicutes,4HRMU@91061|Bacilli	91061|Bacilli	D	Antitoxin component of a toxin-antitoxin (TA) module	yefM	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
IGHDCBEA_00310	435842.HMPREF0848_01254	9.67e-251	689.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0348 family	ylbM	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
IGHDCBEA_00311	435842.HMPREF0848_01255	5.04e-176	490.0	COG0500@1|root,COG2226@2|Bacteria,1V24K@1239|Firmicutes,4HDFY@91061|Bacilli	91061|Bacilli	Q	Methyltransferase domain protein	XK27_06665	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
IGHDCBEA_00312	904306.HMPREF9192_0760	5.28e-76	227.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
IGHDCBEA_00313	435842.HMPREF0848_01257	2.35e-112	323.0	COG1335@1|root,COG1335@2|Bacteria,1VF7P@1239|Firmicutes,4HQSB@91061|Bacilli	91061|Bacilli	Q	Isochorismatase family	yveA	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
IGHDCBEA_00314	904306.HMPREF9192_0758	4.92e-136	385.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli	91061|Bacilli	H	HD superfamily hydrolase involved in NAD metabolism	yqeK	-	-	-	-	-	-	-	-	-	-	-	HD
IGHDCBEA_00315	1046629.Ssal_00417	2.16e-150	422.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
IGHDCBEA_00316	1046629.Ssal_00416	4.57e-65	198.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli	91061|Bacilli	J	RNA-binding protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
IGHDCBEA_00317	1046629.Ssal_00415	2.67e-273	747.0	COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli	91061|Bacilli	S	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis	yqeH	GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113	-	ko:K06948	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
IGHDCBEA_00318	264199.stu1622	3.57e-125	356.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli	91061|Bacilli	S	hydrolase of the HAD superfamily	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
IGHDCBEA_00319	1046629.Ssal_00413	4.56e-181	508.0	COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IGHDCBEA_00320	435842.HMPREF0848_01264	3.29e-82	243.0	2B9ZC@1|root,323D0@2|Bacteria,1VBNR@1239|Firmicutes,4HNA3@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00321	176090.SSIN_0689	5.8e-279	768.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HDVN@91061|Bacilli	91061|Bacilli	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	celD	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
IGHDCBEA_00322	171101.spr0281	7.19e-76	231.0	2E5MG@1|root,303YF@2|Bacteria,1TVHS@1239|Firmicutes,4I4RK@91061|Bacilli,1WUBA@1313|Streptococcus pneumoniae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00323	1054460.SPPN_09960	1.66e-53	169.0	COG1447@1|root,COG1447@2|Bacteria,1VAWR@1239|Firmicutes,4HM7W@91061|Bacilli	91061|Bacilli	G	Phosphotransferase system cellobiose-specific component IIA	celC	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIA
IGHDCBEA_00324	373153.SPD_0280	0.0	951.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli,1WUWZ@1313|Streptococcus pneumoniae	91061|Bacilli	GKT	Mga helix-turn-helix domain	celR	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
IGHDCBEA_00325	862967.SIR_1124	5.81e-63	193.0	COG1440@1|root,COG1440@2|Bacteria,1VAE8@1239|Firmicutes,4HKQ2@91061|Bacilli,42ED8@671232|Streptococcus anginosus group	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	celB	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
IGHDCBEA_00326	1054460.SPPN_09975	1.09e-42	140.0	COG4095@1|root,COG4095@2|Bacteria,1VF4D@1239|Firmicutes,4I0UK@91061|Bacilli	91061|Bacilli	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
IGHDCBEA_00327	1054460.SPPN_09980	0.0	972.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	celA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
IGHDCBEA_00329	1046629.Ssal_00411	0.0	944.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
IGHDCBEA_00330	904306.HMPREF9192_0732	0.0	932.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
IGHDCBEA_00331	1046629.Ssal_00409	7.49e-64	195.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
IGHDCBEA_00332	904306.HMPREF9192_0730	6.68e-57	177.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.52	ko:K00712	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_A_1,Glyco_transf_4,Glycos_transf_1,Glyphos_transf
IGHDCBEA_00333	1046629.Ssal_00406	0.0	1002.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	ascB	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
IGHDCBEA_00334	1046629.Ssal_00405	2.9e-128	364.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli	91061|Bacilli	Q	isochorismatase	pncA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	Isochorismatase
IGHDCBEA_00335	904306.HMPREF9192_0726	8.63e-180	501.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli	91061|Bacilli	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
IGHDCBEA_00336	1046629.Ssal_00403	1.76e-301	821.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HD83@91061|Bacilli	91061|Bacilli	E	Aminotransferase	aspC	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IGHDCBEA_00337	1046629.Ssal_00402	6.2e-98	285.0	COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli	91061|Bacilli	T	universal stress protein	XK27_03180	-	-	-	-	-	-	-	-	-	-	-	Usp
IGHDCBEA_00339	1046629.Ssal_00399	1.21e-202	559.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli	91061|Bacilli	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
IGHDCBEA_00341	1046629.Ssal_00397	9.57e-303	827.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli	91061|Bacilli	S	COG1253 Hemolysins and related proteins containing CBS domains	hlyX	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
IGHDCBEA_00342	1046629.Ssal_00395	3.03e-184	512.0	COG1119@1|root,COG1119@2|Bacteria,1TRR4@1239|Firmicutes,4HB4U@91061|Bacilli	91061|Bacilli	P	abc transporter atp-binding protein	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
IGHDCBEA_00343	1046629.Ssal_00394	0.0	1250.0	COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli	91061|Bacilli	P	NhaP-type Na H and K H antiporters	nhaP1	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
IGHDCBEA_00345	1046629.Ssal_00392	1.23e-124	355.0	COG0144@1|root,COG0144@2|Bacteria,1UHQD@1239|Firmicutes,4HIMC@91061|Bacilli	91061|Bacilli	J	(SAM)-dependent	mraW1	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
IGHDCBEA_00346	1046629.Ssal_00391	3.57e-235	645.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli	91061|Bacilli	S	radical SAM protein	ytqA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
IGHDCBEA_00347	435842.HMPREF0848_01289	3.41e-237	654.0	COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli	91061|Bacilli	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
IGHDCBEA_00348	1046629.Ssal_00388	6.51e-114	327.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli	91061|Bacilli	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
IGHDCBEA_00349	1046629.Ssal_00387	7.69e-120	343.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli	91061|Bacilli	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
IGHDCBEA_00350	1046629.Ssal_00386	4.59e-218	602.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
IGHDCBEA_00351	40041.SZO_03890	3.64e-14	67.8	29I01@1|root,304X3@2|Bacteria,1TXCH@1239|Firmicutes,4I6AC@91061|Bacilli,1M9T3@119603|Streptococcus dysgalactiae group	91061|Bacilli	S	Protein of unknown function (DUF4059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4059
IGHDCBEA_00352	1046629.Ssal_00383	1.32e-167	469.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	tcyN	-	3.6.3.21	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	M00234,M00236,M00585	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14	-	-	ABC_tran
IGHDCBEA_00353	1046629.Ssal_00382	4.19e-210	582.0	COG0765@1|root,COG0765@2|Bacteria,1UZ2C@1239|Firmicutes,4HF77@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	yxeN	-	-	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	M00236,M00585,M00586	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.13	-	-	BPD_transp_1
IGHDCBEA_00354	1046629.Ssal_00380	3.16e-194	539.0	COG0834@1|root,COG0834@2|Bacteria,1V7WQ@1239|Firmicutes,4HK1Z@91061|Bacilli	91061|Bacilli	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IGHDCBEA_00356	904306.HMPREF9192_0701	3.58e-260	713.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IGHDCBEA_00357	1046629.Ssal_00375	0.0	1565.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli	91061|Bacilli	C	formate acetyltransferase'	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
IGHDCBEA_00359	1046629.Ssal_00373	0.0	1136.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli	91061|Bacilli	S	Myosin-crossreactive antigen	l1n	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
IGHDCBEA_00360	1046629.Ssal_00372	1.06e-184	513.0	COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli	91061|Bacilli	P	carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
IGHDCBEA_00361	435842.HMPREF0848_01310	1.71e-95	279.0	COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli	91061|Bacilli	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yjcF	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
IGHDCBEA_00363	1046629.Ssal_00368	3.22e-218	603.0	COG1680@1|root,COG1680@2|Bacteria,1TNZX@1239|Firmicutes,4IPJT@91061|Bacilli	91061|Bacilli	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
IGHDCBEA_00364	1046629.Ssal_00367	5.62e-181	503.0	COG0346@1|root,COG0346@2|Bacteria,1VMPM@1239|Firmicutes,4HSVM@91061|Bacilli	91061|Bacilli	E	CppA N-terminal	cppA	-	-	-	-	-	-	-	-	-	-	-	CppA_C,CppA_N
IGHDCBEA_00365	1046629.Ssal_00366	2.86e-127	364.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IGHDCBEA_00366	1046629.Ssal_00365	7.88e-210	579.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HE39@91061|Bacilli	91061|Bacilli	U	Belongs to the MIP aquaporin (TC 1.A.8) family	gla	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
IGHDCBEA_00367	1046629.Ssal_00364	0.0	1513.0	COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli	91061|Bacilli	E	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline	pepX	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,PepX_N,Peptidase_S15
IGHDCBEA_00377	435842.HMPREF0848_01339	0.0	1080.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	mdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_00378	1046629.Ssal_00350	0.0	1112.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	mdlA	-	-	ko:K06148,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
IGHDCBEA_00380	1046629.Ssal_00348	9.07e-119	340.0	COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HQZW@91061|Bacilli	91061|Bacilli	V	Glycopeptide antibiotics resistance protein	XK27_09885	-	-	-	-	-	-	-	-	-	-	-	VanZ
IGHDCBEA_00381	1046629.Ssal_00347	7.84e-286	780.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli	91061|Bacilli	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
IGHDCBEA_00382	264199.stu1697	3.22e-107	316.0	COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli	91061|Bacilli	J	protein conserved in bacteria	yutD	-	-	-	-	-	-	-	-	-	-	-	DUF1027
IGHDCBEA_00383	1046629.Ssal_00344	0.0	884.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	yunD	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
IGHDCBEA_00385	1046629.Ssal_00342	1.86e-302	827.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli	91061|Bacilli	JKL	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures	cshB	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592,ko:K18692	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
IGHDCBEA_00386	1046629.Ssal_00341	8.08e-236	649.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli	91061|Bacilli	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
IGHDCBEA_00387	435842.HMPREF0848_01353	0.0	1391.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli	91061|Bacilli	M	penicillin-binding protein	pbpX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
IGHDCBEA_00388	435842.HMPREF0848_01354	5.32e-60	186.0	COG4839@1|root,COG4839@2|Bacteria,1VCE5@1239|Firmicutes,4HM4W@91061|Bacilli	91061|Bacilli	D	cell division protein FtsL	ftsL	-	-	-	-	-	-	-	-	-	-	-	DivIC
IGHDCBEA_00389	322159.STER_1668	5.38e-222	612.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli	91061|Bacilli	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
IGHDCBEA_00390	264199.stu1704	2.09e-148	428.0	2DDKD@1|root,2ZIF1@2|Bacteria,1W5UA@1239|Firmicutes,4HZND@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00392	1046629.Ssal_00333	9.53e-57	179.0	COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli	91061|Bacilli	J	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
IGHDCBEA_00393	1046629.Ssal_00333	2.34e-73	221.0	COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli	91061|Bacilli	J	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
IGHDCBEA_00394	585204.SMSK597_1064	4.02e-112	338.0	COG1403@1|root,COG1403@2|Bacteria,1V4V2@1239|Firmicutes,4HI4X@91061|Bacilli	91061|Bacilli	L	Endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
IGHDCBEA_00395	904306.HMPREF9192_0661	5.94e-28	107.0	COG3152@1|root,COG3152@2|Bacteria,1VG9E@1239|Firmicutes,4HQYQ@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
IGHDCBEA_00396	904306.HMPREF9192_0660	1.12e-285	782.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli	91061|Bacilli	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU13130	Aldedh
IGHDCBEA_00397	904306.HMPREF9192_0659	2.37e-180	503.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli	91061|Bacilli	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
IGHDCBEA_00398	1046629.Ssal_00329	0.0	983.0	28MBB@1|root,2ZAPV@2|Bacteria,1TSZA@1239|Firmicutes,4HDKH@91061|Bacilli	91061|Bacilli	-	-	XK27_00765	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
IGHDCBEA_00399	1046629.Ssal_00328	2.59e-172	481.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCEU@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	ecsA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_00400	1046629.Ssal_00327	1.73e-161	453.0	COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,4HEYY@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
IGHDCBEA_00401	1046629.Ssal_00325	0.0	2288.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	addA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
IGHDCBEA_00402	1046629.Ssal_00322	0.0	2096.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli	91061|Bacilli	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination	rexB	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
IGHDCBEA_00403	1046629.Ssal_00321	1.72e-303	830.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5,PAS_9
IGHDCBEA_00404	1046629.Ssal_00320	5.79e-289	792.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	dcuS	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0035556,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141	2.7.13.3	ko:K02476,ko:K07701,ko:K07706,ko:K11614	ko02020,ko02024,map02020,map02024	M00488,M00490,M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,SPOB_a,sCache_3_2
IGHDCBEA_00405	365659.smi_1723	2.64e-14	84.3	2DKFM@1|root,309CC@2|Bacteria,1U4TK@1239|Firmicutes,4IEJ2@91061|Bacilli,2TQA8@28037|Streptococcus mitis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00408	1046629.Ssal_00316	8.38e-187	519.0	COG1131@1|root,COG1131@2|Bacteria,1V0ED@1239|Firmicutes	1239|Firmicutes	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
IGHDCBEA_00410	1046629.Ssal_00314	0.0	1029.0	COG0443@1|root,COG0443@2|Bacteria,1TSUC@1239|Firmicutes	1239|Firmicutes	O	MreB/Mbl protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
IGHDCBEA_00411	322159.STER_1683	5.48e-143	405.0	COG4758@1|root,COG4758@2|Bacteria,1VGSF@1239|Firmicutes,4IRBC@91061|Bacilli	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00412	1046629.Ssal_00312	1.34e-98	287.0	COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,4HHGZ@91061|Bacilli	91061|Bacilli	K	LytTr DNA-binding domain protein	XK27_02470	-	-	-	-	-	-	-	-	-	-	-	LytTR
IGHDCBEA_00413	1046629.Ssal_00311	0.0	1086.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00414	1046629.Ssal_00310	8.29e-185	526.0	COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli	91061|Bacilli	M	Membrane	yebC	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3,zinc_ribbon_2
IGHDCBEA_00415	1046629.Ssal_00309	0.0	903.0	COG0561@1|root,COG4696@1|root,COG0561@2|Bacteria,COG4696@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli	91061|Bacilli	S	hydrolases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,PRA-PH
IGHDCBEA_00416	1046629.Ssal_00308	2.03e-228	629.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli	91061|Bacilli	EJ	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
IGHDCBEA_00418	1046629.Ssal_00306	4.07e-43	140.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	yozG	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
IGHDCBEA_00422	1046629.Ssal_00303	3.15e-157	443.0	2CSEJ@1|root,32SR2@2|Bacteria,1VA63@1239|Firmicutes,4HMDZ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
IGHDCBEA_00423	1046629.Ssal_00301	1.2e-203	564.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HEPD@91061|Bacilli	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_00425	435842.HMPREF0848_01388	0.0	1291.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli	91061|Bacilli	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
IGHDCBEA_00426	1046629.Ssal_00297	5.24e-257	705.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli	91061|Bacilli	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,5.1.1.5	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
IGHDCBEA_00427	1046629.Ssal_00296	2.5e-79	235.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli	91061|Bacilli	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iYO844.BSU04620	ACPS
IGHDCBEA_00428	1046629.Ssal_00295	9.04e-250	686.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes	1239|Firmicutes	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
IGHDCBEA_00429	1046629.Ssal_00294	1.67e-250	687.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes	1239|Firmicutes	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
IGHDCBEA_00430	1046629.Ssal_00292	0.0	1657.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
IGHDCBEA_00432	1046629.Ssal_00290	8.8e-241	660.0	COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli	91061|Bacilli	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU12020	PMI_typeI
IGHDCBEA_00433	1046629.Ssal_00289	1.13e-218	602.0	COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli	91061|Bacilli	GK	Fructokinase	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
IGHDCBEA_00434	1046629.Ssal_00287	0.0	1204.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli	91061|Bacilli	G	pts system	scrA	-	2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
IGHDCBEA_00435	904306.HMPREF9192_0628	0.0	984.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli	91061|Bacilli	G	invertase	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
IGHDCBEA_00436	1046629.Ssal_00285	5.83e-224	618.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IGHDCBEA_00437	1046629.Ssal_00284	1.09e-95	279.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli	91061|Bacilli	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
IGHDCBEA_00438	1046629.Ssal_00283	7.41e-80	238.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	WQ51_04310	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	Asp23
IGHDCBEA_00439	1046629.Ssal_00282	1.22e-126	360.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli	91061|Bacilli	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
IGHDCBEA_00440	1046629.Ssal_00281	3.59e-111	318.0	COG2131@1|root,COG2131@2|Bacteria,1V8V0@1239|Firmicutes,4IQZA@91061|Bacilli	91061|Bacilli	F	ComE operon protein 2	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
IGHDCBEA_00441	1046629.Ssal_00280	5.88e-256	701.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli	91061|Bacilli	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
IGHDCBEA_00442	1123298.KB904096_gene254	2.65e-38	145.0	2DWQH@1|root,341F6@2|Bacteria,1W6SH@1239|Firmicutes,4HX74@91061|Bacilli	91061|Bacilli	-	-	blpT	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
IGHDCBEA_00446	1046629.Ssal_00276	0.0	1867.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
IGHDCBEA_00447	1046629.Ssal_00275	6.27e-217	599.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli	91061|Bacilli	P	COG0598 Mg2 and Co2 transporters	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
IGHDCBEA_00448	1046629.Ssal_00273	8.39e-159	445.0	COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HMVT@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1129)	XK27_01040	-	-	-	-	-	-	-	-	-	-	-	DUF1129
IGHDCBEA_00450	1046629.Ssal_00271	4.1e-47	151.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli	91061|Bacilli	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
IGHDCBEA_00451	904306.HMPREF9192_0609	4.18e-118	338.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
IGHDCBEA_00452	1046629.Ssal_00269	6.54e-63	192.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli	91061|Bacilli	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
IGHDCBEA_00453	1214166.ALLG01000021_gene137	3.64e-54	185.0	2BJFN@1|root,32DS8@2|Bacteria,1U8WY@1239|Firmicutes,4IIVI@91061|Bacilli,1WSBS@1307|Streptococcus suis	91061|Bacilli	-	-	XK27_05745	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00454	1046629.Ssal_00266	5.55e-292	795.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli	91061|Bacilli	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
IGHDCBEA_00456	365659.smi_1282	2.62e-09	58.9	2DKAS@1|root,30920@2|Bacteria,1U4B0@1239|Firmicutes,4IE2N@91061|Bacilli,2TP5R@28037|Streptococcus mitis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00457	397288.C806_03616	4.59e-49	160.0	2DZDF@1|root,32V7U@2|Bacteria,1VB8V@1239|Firmicutes,24KMP@186801|Clostridia,27ME7@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00458	904306.HMPREF9192_0604	0.0	1687.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
IGHDCBEA_00459	1046629.Ssal_00253	0.0	1479.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
IGHDCBEA_00460	1046629.Ssal_00251	4.82e-121	346.0	COG1286@1|root,COG1286@2|Bacteria	2|Bacteria	S	toxin biosynthetic process	cvpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V,Trypsin_2
IGHDCBEA_00461	1302863.I872_01550	1.18e-20	85.1	COG3027@1|root,COG3027@2|Bacteria,1VFZS@1239|Firmicutes,4HP4T@91061|Bacilli	91061|Bacilli	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
IGHDCBEA_00462	1046629.Ssal_00249	7.52e-199	552.0	COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF3378,RNase_HII
IGHDCBEA_00463	1046629.Ssal_00248	3.7e-148	417.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HMGQ@91061|Bacilli	91061|Bacilli	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
IGHDCBEA_00464	1046629.Ssal_00246	0.0	1581.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli	91061|Bacilli	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
IGHDCBEA_00465	435842.HMPREF0848_01433	1.33e-61	190.0	COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,4HRBI@91061|Bacilli	91061|Bacilli	S	branched-chain amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
IGHDCBEA_00466	435842.HMPREF0848_01434	3.29e-144	409.0	COG1296@1|root,COG1296@2|Bacteria,1V64T@1239|Firmicutes,4HH44@91061|Bacilli	91061|Bacilli	E	AzlC protein	XK27_12120	-	-	-	-	-	-	-	-	-	-	-	AzlC
IGHDCBEA_00467	1046629.Ssal_00242	3.86e-237	652.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli	91061|Bacilli	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
IGHDCBEA_00468	322159.STER_1746	2.98e-94	275.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HP50@91061|Bacilli	91061|Bacilli	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
IGHDCBEA_00469	435842.HMPREF0848_01437	4.74e-146	414.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli	91061|Bacilli	O	COG1214, inactive homolog of metal-dependent proteases	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
IGHDCBEA_00470	1046629.Ssal_00239	5.31e-44	143.0	COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0356 family	ykzG	-	-	-	-	-	-	-	-	-	-	-	DUF1447
IGHDCBEA_00471	435842.HMPREF0848_01439	0.0	1108.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnjA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
IGHDCBEA_00472	1046629.Ssal_00236	4.35e-150	422.0	COG3942@1|root,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4HIMT@91061|Bacilli	91061|Bacilli	M	CHAP domain protein	sle1	-	3.5.1.28	ko:K22409	-	-	-	-	ko00000,ko01000	-	CBM50	-	CHAP,LysM
IGHDCBEA_00473	1046629.Ssal_00235	0.0	907.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli	91061|Bacilli	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
IGHDCBEA_00474	1046629.Ssal_00234	4e-82	243.0	COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	glnR	GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141	-	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	MerR_1
IGHDCBEA_00475	1046629.Ssal_00233	3.08e-113	325.0	COG4129@1|root,COG4129@2|Bacteria,1VAJG@1239|Firmicutes,4HKDZ@91061|Bacilli	91061|Bacilli	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	ArAE_1,FUSC_2
IGHDCBEA_00476	1046629.Ssal_00232	3.32e-283	774.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli	91061|Bacilli	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145	PGK
IGHDCBEA_00478	1046629.Ssal_00230	1.41e-239	659.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
IGHDCBEA_00479	1046629.Ssal_00229	0.0	1358.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli	91061|Bacilli	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
IGHDCBEA_00480	1046629.Ssal_00227	4.66e-105	303.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
IGHDCBEA_00481	1046629.Ssal_00226	4.89e-91	266.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli	91061|Bacilli	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
IGHDCBEA_00482	904306.HMPREF9192_0573	7.91e-184	512.0	COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli	91061|Bacilli	F	operon repressor	purR	-	-	ko:K09685	-	-	-	-	ko00000,ko03000	-	-	-	Pribosyltran,PuR_N
IGHDCBEA_00483	1046629.Ssal_00224	1.69e-228	629.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli	91061|Bacilli	S	3'-5' exoribonuclease yhaM	yhaM	GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
IGHDCBEA_00484	1046629.Ssal_00223	2.42e-231	645.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,4HE2N@91061|Bacilli	91061|Bacilli	S	RmuC domain protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
IGHDCBEA_00485	1046629.Ssal_00222	1.35e-153	431.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli	91061|Bacilli	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
IGHDCBEA_00486	1046629.Ssal_00221	2.31e-154	433.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
IGHDCBEA_00487	1046629.Ssal_00220	1.36e-211	584.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli	91061|Bacilli	G	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
IGHDCBEA_00489	1046629.Ssal_00219	1.24e-198	551.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
IGHDCBEA_00490	1046629.Ssal_00218	2.57e-128	365.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli	91061|Bacilli	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step	rnmV	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
IGHDCBEA_00491	1046629.Ssal_00217	2.25e-183	510.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli	91061|Bacilli	L	Hydrolase, tatd	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
IGHDCBEA_00492	1046629.Ssal_00216	2.12e-97	283.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli	91061|Bacilli	S	CoA-binding protein	yneT	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
IGHDCBEA_00493	904306.HMPREF9192_0562	3.11e-67	204.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli	91061|Bacilli	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IGHDCBEA_00494	1046629.Ssal_00214	4.31e-184	512.0	COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,4HCXD@91061|Bacilli	91061|Bacilli	S	Macro domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
IGHDCBEA_00495	435842.HMPREF0848_01462	3.68e-77	231.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli	91061|Bacilli	L	thioesterase	yneP	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
IGHDCBEA_00496	1046629.Ssal_00210	4.62e-70	211.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	bta	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin,TraF
IGHDCBEA_00498	1046629.Ssal_00931	0.0	1134.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HBKC@91061|Bacilli	91061|Bacilli	EH	component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
IGHDCBEA_00499	1046629.Ssal_00930	0.0	1646.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli	91061|Bacilli	P	cation transport ATPase	-	-	3.6.3.2,3.6.3.6,3.6.3.8	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3,3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
IGHDCBEA_00500	1046629.Ssal_00929	5.4e-312	849.0	COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli	91061|Bacilli	M	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)	dltD	-	-	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	DltD
IGHDCBEA_00501	1046629.Ssal_00928	7.07e-48	153.0	COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli	91061|Bacilli	IQ	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	dltC	GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	PP-binding
IGHDCBEA_00502	1046629.Ssal_00927	5.31e-304	828.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli	91061|Bacilli	M	Membrane protein involved in D-alanine export	dltB	-	-	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
IGHDCBEA_00503	1046629.Ssal_00926	0.0	1028.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli	91061|Bacilli	Q	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall	dltA	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	AMP-binding,AMP-binding_C
IGHDCBEA_00504	1046629.Ssal_00924	0.0	1100.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HCVN@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	XK27_10035	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_00505	904306.HMPREF9192_1216	0.0	998.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	yfiB1	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_00506	264199.stu0757	5.07e-127	363.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	pvaA	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Lysozyme_like,SLT_2
IGHDCBEA_00507	904306.HMPREF9192_1214	3.67e-229	631.0	COG3081@1|root,COG3081@2|Bacteria,1V437@1239|Firmicutes,4IQXJ@91061|Bacilli	91061|Bacilli	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
IGHDCBEA_00508	904306.HMPREF9192_1213	5.41e-293	800.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
IGHDCBEA_00509	1005704.HMPREF9968_1649	4.76e-81	242.0	COG0454@1|root,COG0456@2|Bacteria,1V5YQ@1239|Firmicutes,4HMFB@91061|Bacilli,1WPIA@1303|Streptococcus oralis	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IGHDCBEA_00510	1046629.Ssal_00919	4.32e-130	370.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli	91061|Bacilli	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
IGHDCBEA_00511	1046629.Ssal_00918	2.37e-185	516.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli	91061|Bacilli	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
IGHDCBEA_00512	1046629.Ssal_00917	1.6e-247	681.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli	91061|Bacilli	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
IGHDCBEA_00513	904306.HMPREF9192_1209	2.86e-140	396.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli	91061|Bacilli	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
IGHDCBEA_00514	1046629.Ssal_00915	6.91e-235	647.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli	91061|Bacilli	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	M00236	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	A_deaminase
IGHDCBEA_00515	1046629.Ssal_00914	3.57e-193	535.0	COG0625@1|root,COG0625@2|Bacteria,1TPZ7@1239|Firmicutes,4HD0K@91061|Bacilli	91061|Bacilli	O	Glutathione S-transferase	gst	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_2
IGHDCBEA_00516	1046629.Ssal_00913	2.04e-225	621.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli	91061|Bacilli	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
IGHDCBEA_00517	1046629.Ssal_00912	2.58e-226	623.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HDFE@91061|Bacilli	91061|Bacilli	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
IGHDCBEA_00518	1046629.Ssal_00910	3.52e-61	187.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli	91061|Bacilli	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
IGHDCBEA_00519	1046629.Ssal_00908	4.28e-292	798.0	COG1914@1|root,COG1914@2|Bacteria,1V04N@1239|Firmicutes,4HBF6@91061|Bacilli	91061|Bacilli	P	Mn2 and Fe2 transporters of the NRAMP family	mntH_2	-	-	-	-	-	-	-	-	-	-	-	Nramp
IGHDCBEA_00520	1046629.Ssal_00907	1.62e-210	584.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli	91061|Bacilli	S	secreted protein	ypuA	-	-	-	-	-	-	-	-	-	-	-	DUF1002
IGHDCBEA_00521	1046629.Ssal_00906	3.04e-93	272.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli	91061|Bacilli	E	COG0346 Lactoylglutathione lyase and related lyases	ywkD	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
IGHDCBEA_00522	1046629.Ssal_00905	3.1e-169	474.0	COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HIA0@91061|Bacilli	91061|Bacilli	M	Sortase (surface protein transpeptidase)	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IGHDCBEA_00523	1046629.Ssal_00904	0.0	1462.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
IGHDCBEA_00524	1046629.Ssal_00903	7.17e-233	641.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli	91061|Bacilli	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
IGHDCBEA_00525	1046629.Ssal_00902	0.0	888.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli	91061|Bacilli	P	NADH oxidase	noxE	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
IGHDCBEA_00526	1046629.Ssal_00901	0.0	1006.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	yheS_1	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
IGHDCBEA_00527	1046629.Ssal_00900	4.61e-108	313.0	COG4720@1|root,COG4720@2|Bacteria,1VC0F@1239|Firmicutes,4HMJM@91061|Bacilli	91061|Bacilli	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
IGHDCBEA_00528	1046629.Ssal_00899	3.6e-184	514.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli	91061|Bacilli	H	Belongs to the pyridoxine kinase family	pdxK	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
IGHDCBEA_00529	904306.HMPREF9192_1484	2.5e-104	303.0	COG4720@1|root,COG4720@2|Bacteria,1V6QK@1239|Firmicutes	1239|Firmicutes	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
IGHDCBEA_00531	1046629.Ssal_00896	8.14e-302	823.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HBNK@91061|Bacilli	91061|Bacilli	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	ycxD	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
IGHDCBEA_00532	1046629.Ssal_00894	6.52e-75	224.0	COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes	1239|Firmicutes	F	Ribonucleoside-triphosphate reductase	nrdD_1	-	1.1.98.6,1.17.4.1	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC
IGHDCBEA_00534	1046629.Ssal_00892	0.0	1544.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
IGHDCBEA_00535	1046629.Ssal_00891	3.73e-121	345.0	COG0454@1|root,COG0456@2|Bacteria,1VDFK@1239|Firmicutes,4HMHW@91061|Bacilli	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	XK27_03150	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
IGHDCBEA_00536	1046629.Ssal_00890	1.38e-251	690.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
IGHDCBEA_00537	1000570.HMPREF9966_0177	7.46e-32	111.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNKW@91061|Bacilli,42DRV@671232|Streptococcus anginosus group	91061|Bacilli	K	Helix-turn-helix domain	WQ51_00220	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
IGHDCBEA_00538	1046629.Ssal_00888	1.81e-121	347.0	2EQR3@1|root,33IAY@2|Bacteria,1VK6G@1239|Firmicutes,4HRX8@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3278)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3278
IGHDCBEA_00539	1046629.Ssal_00887	0.0	1790.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
IGHDCBEA_00540	1046629.Ssal_00886	2.63e-160	449.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli	91061|Bacilli	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
IGHDCBEA_00541	1046629.Ssal_00884	8.96e-223	614.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli	91061|Bacilli	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
IGHDCBEA_00542	1046629.Ssal_00883	5.02e-255	699.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli	91061|Bacilli	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
IGHDCBEA_00544	1046629.Ssal_00880	0.0	994.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA_1	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
IGHDCBEA_00545	904306.HMPREF9192_1469	4.03e-115	330.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli	91061|Bacilli	M	acetyltransferase	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
IGHDCBEA_00546	904306.HMPREF9192_1468	0.0	942.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
IGHDCBEA_00547	1046629.Ssal_00877	0.0	1177.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
IGHDCBEA_00548	1046629.Ssal_00875	3.04e-165	462.0	COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,4HEXU@91061|Bacilli	91061|Bacilli	E	hydrolase	yfnB	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
IGHDCBEA_00549	1046629.Ssal_00874	1.14e-156	439.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli	91061|Bacilli	E	L-serine dehydratase	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
IGHDCBEA_00550	1046629.Ssal_00873	5.58e-190	529.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli	91061|Bacilli	E	L-serine dehydratase	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
IGHDCBEA_00551	1046629.Ssal_00871	0.0	2464.0	COG1621@1|root,COG3583@1|root,COG5492@1|root,COG1621@2|Bacteria,COG3583@2|Bacteria,COG5492@2|Bacteria,1TS4M@1239|Firmicutes	1239|Firmicutes	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Big_2,CW_binding_1,Cadherin-like,DUF1080,G5,Glyco_hydro_32C,Glyco_hydro_32N,Gram_pos_anchor,Laminin_G_2
IGHDCBEA_00552	1046629.Ssal_00868	1.89e-128	370.0	COG0697@1|root,COG0697@2|Bacteria,1TP9B@1239|Firmicutes,4H9TT@91061|Bacilli	91061|Bacilli	EG	membrane	yjlA	-	-	-	-	-	-	-	-	-	-	-	EmrE
IGHDCBEA_00553	904306.HMPREF9192_2004	3.88e-303	826.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
IGHDCBEA_00554	1046629.Ssal_00136	0.0	1545.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli	91061|Bacilli	M	penicillin-binding protein	pbp1B	-	2.4.1.129	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
IGHDCBEA_00555	1046629.Ssal_00138	0.0	2332.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli	91061|Bacilli	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
IGHDCBEA_00556	904306.HMPREF9192_2007	0.0	2380.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli	91061|Bacilli	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
IGHDCBEA_00557	1046629.Ssal_00141	1.37e-91	266.0	COG4699@1|root,COG4699@2|Bacteria,1VHC7@1239|Firmicutes,4HS15@91061|Bacilli	91061|Bacilli	S	cog cog4699	-	-	-	-	-	-	-	-	-	-	-	-	DUF1033
IGHDCBEA_00558	1046629.Ssal_00142	3.65e-223	615.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli	91061|Bacilli	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	comGA	-	-	ko:K02243	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.14.1	-	-	T2SSE
IGHDCBEA_00559	1046629.Ssal_00143	3.79e-185	516.0	COG1459@1|root,COG1459@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	cglB	-	-	ko:K02244	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.14.1	-	-	T2SSF
IGHDCBEA_00560	1046629.Ssal_00144	1.83e-61	189.0	COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli	91061|Bacilli	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	N_methyl
IGHDCBEA_00561	1046629.Ssal_00145	9.78e-92	269.0	COG2165@1|root,33A38@2|Bacteria,1VPGT@1239|Firmicutes,4HRZ0@91061|Bacilli	91061|Bacilli	NU	Competence protein	cglD	-	-	ko:K02246	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	-
IGHDCBEA_00562	873449.STRCR_0577	3.03e-22	89.0	COG2165@1|root,2ZS6J@2|Bacteria,1W385@1239|Firmicutes	1239|Firmicutes	NU	Type II secretory pathway pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	PulG
IGHDCBEA_00563	1046629.Ssal_00147	3.23e-93	273.0	COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli	91061|Bacilli	U	Competence protein ComGF	comGF	-	-	ko:K02248	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComGF,N_methyl
IGHDCBEA_00564	1198676.SMUGS5_08910	7.17e-17	80.5	COG4940@1|root,COG4940@2|Bacteria,1VJKM@1239|Firmicutes,4HQDT@91061|Bacilli	91061|Bacilli	U	Putative Competence protein ComGF	-	-	-	ko:K02248	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComGF,N_methyl
IGHDCBEA_00565	1046629.Ssal_00149	1.13e-224	619.0	COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli	91061|Bacilli	L	DNA methylase	ytxK	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
IGHDCBEA_00566	904306.HMPREF9192_2018	7.15e-277	758.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli	91061|Bacilli	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
IGHDCBEA_00567	1046629.Ssal_00151	1.05e-36	124.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	lanR	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
IGHDCBEA_00568	1046629.Ssal_00152	1.13e-124	358.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IGHDCBEA_00570	264199.stu1853	1.53e-123	355.0	COG1266@1|root,COG1266@2|Bacteria,1VEE2@1239|Firmicutes,4HP4A@91061|Bacilli	91061|Bacilli	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IGHDCBEA_00571	1046629.Ssal_00155	5.55e-169	473.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4HCBY@91061|Bacilli	91061|Bacilli	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
IGHDCBEA_00572	1046629.Ssal_00156	8.37e-257	704.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli	91061|Bacilli	G	COG1363 Cellulase M and related proteins	pepA	-	3.4.11.7	ko:K01261,ko:K01269	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M42
IGHDCBEA_00574	1046629.Ssal_00158	2.86e-72	216.0	COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli	91061|Bacilli	CO	Thioredoxin	ytpP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Thioredoxin
IGHDCBEA_00576	1046629.Ssal_00160	4.53e-146	411.0	COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	XK27_10290	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	DUF4479,tRNA_bind
IGHDCBEA_00577	322159.STER_1823	9.13e-239	657.0	COG2391@1|root,COG2391@2|Bacteria,1TSNG@1239|Firmicutes,4HDN0@91061|Bacilli	91061|Bacilli	S	Sulphur transport	yeeE	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
IGHDCBEA_00578	322159.STER_1822	3.2e-49	156.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	yeeD	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp,TusA
IGHDCBEA_00579	322159.STER_1821	1.28e-85	252.0	COG0629@1|root,COG0629@2|Bacteria,1VXMZ@1239|Firmicutes,4HXCW@91061|Bacilli	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
IGHDCBEA_00580	1046629.Ssal_00164	8.11e-116	332.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli	91061|Bacilli	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
IGHDCBEA_00584	904306.HMPREF9192_2035	6.42e-200	553.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	rrmA	-	2.1.1.187	ko:K00563,ko:K10947	-	-	R07233	RC00003	ko00000,ko01000,ko03000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
IGHDCBEA_00585	1046629.Ssal_00169	1.97e-175	489.0	COG0546@1|root,COG0546@2|Bacteria,1V73N@1239|Firmicutes,4IU82@91061|Bacilli	91061|Bacilli	S	HAD hydrolase, family IA, variant	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
IGHDCBEA_00586	1046629.Ssal_00170	5.89e-107	315.0	COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli	91061|Bacilli	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate	dapH	-	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU14180	DapH_N,Hexapep
IGHDCBEA_00587	1046629.Ssal_00172	1.9e-280	765.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli	91061|Bacilli	E	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate	hipO	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.47	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
IGHDCBEA_00588	1046629.Ssal_00173	4.68e-121	345.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
IGHDCBEA_00589	1046629.Ssal_00174	2.2e-150	424.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli	91061|Bacilli	O	membrane protein (homolog of Drosophila rhomboid)	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
IGHDCBEA_00590	1046629.Ssal_00175	1.6e-217	600.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
IGHDCBEA_00591	1046629.Ssal_00176	4.89e-235	648.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli	91061|Bacilli	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
IGHDCBEA_00592	904306.HMPREF9192_2043	1.08e-120	345.0	2BY0N@1|root,321KG@2|Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	XK27_08585	-	-	ko:K16926	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.31	-	-	Trep_Strep
IGHDCBEA_00593	1046629.Ssal_00179	1.49e-181	506.0	COG2116@1|root,COG2116@2|Bacteria,1V164@1239|Firmicutes,4HFJC@91061|Bacilli	91061|Bacilli	P	Formate nitrite transporter	nirC_1	-	-	-	-	-	-	-	-	-	-	-	Form_Nir_trans
IGHDCBEA_00594	1046629.Ssal_00180	1.04e-306	835.0	COG0431@1|root,COG2461@1|root,COG0431@2|Bacteria,COG2461@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli	91061|Bacilli	C	reductase	XK27_09615	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red,PAS_10
IGHDCBEA_00595	1046629.Ssal_00181	3.33e-140	396.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	XK27_09620	-	-	-	-	-	-	-	-	-	-	-	FMN_red
IGHDCBEA_00596	435842.HMPREF0848_01842	7.02e-103	297.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli	91061|Bacilli	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
IGHDCBEA_00597	1095738.HMPREF1047_1312	2.88e-88	261.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
IGHDCBEA_00598	1046629.Ssal_00184	3.1e-287	786.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
IGHDCBEA_00599	1046629.Ssal_00185	1.02e-163	458.0	COG2013@1|root,COG2013@2|Bacteria,1V6BD@1239|Firmicutes,4HIAR@91061|Bacilli	91061|Bacilli	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
IGHDCBEA_00600	1046629.Ssal_00186	4.77e-116	332.0	COG0288@1|root,COG0288@2|Bacteria,1V0TA@1239|Firmicutes,4HB9V@91061|Bacilli	91061|Bacilli	P	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
IGHDCBEA_00601	1046629.Ssal_00187	4.66e-66	202.0	2DSU9@1|root,33HF9@2|Bacteria,1VNK9@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3397
IGHDCBEA_00602	1046629.Ssal_00188	1.69e-93	273.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
IGHDCBEA_00603	1046629.Ssal_00189	1.37e-155	438.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
IGHDCBEA_00604	1046629.Ssal_00190	0.0	1263.0	COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli	91061|Bacilli	E	ABC transporter, substrate-binding protein, family 5	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
IGHDCBEA_00605	1046629.Ssal_00191	0.0	946.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065	6.1.1.24	ko:K09698	ko00970,ko01100,map00970,map01100	M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSB619.SA_RS02860	tRNA-synt_1c
IGHDCBEA_00606	1046629.Ssal_00192	3.53e-294	805.0	COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4IPJ9@91061|Bacilli	91061|Bacilli	T	signal transduction protein with a C-terminal ATPase domain	-	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5
IGHDCBEA_00607	1046629.Ssal_00193	3.4e-199	553.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	hpk9	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5,PAS_9
IGHDCBEA_00608	1046629.Ssal_00194	6.48e-262	721.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	hpk9	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5,PAS_9
IGHDCBEA_00609	1046629.Ssal_00195	6.06e-308	840.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	fasC	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5,PAS_9
IGHDCBEA_00610	1046629.Ssal_00196	5.22e-174	485.0	COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli	91061|Bacilli	KT	Response regulator of the LytR AlgR family	fasA	-	-	ko:K07707	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
IGHDCBEA_00611	322159.STER_1474	1.85e-135	385.0	298VG@1|root,2ZVZK@2|Bacteria,1V1IF@1239|Firmicutes,4HGGM@91061|Bacilli	91061|Bacilli	S	CRISPR-associated protein (Cas_Csn2)	csn2	-	-	ko:K19137	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csn2
IGHDCBEA_00612	322159.STER_1475	9.45e-70	211.0	COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,4HNYR@91061|Bacilli	91061|Bacilli	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
IGHDCBEA_00613	322159.STER_1476	1.84e-204	566.0	COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,4HC5E@91061|Bacilli	91061|Bacilli	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
IGHDCBEA_00614	322159.STER_1477	0.0	2583.0	COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli	91061|Bacilli	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas9-BH,Cas9_PI,Cas9_REC,HNH_4
IGHDCBEA_00615	1046629.Ssal_00560	1.33e-142	403.0	COG0560@1|root,COG0560@2|Bacteria,1V9R7@1239|Firmicutes,4HTNE@91061|Bacilli	91061|Bacilli	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
IGHDCBEA_00616	1046629.Ssal_00559	0.0	1060.0	COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli	91061|Bacilli	D	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization	ezrA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	-	ko:K06286	-	-	-	-	ko00000,ko03036	-	-	-	EzrA
IGHDCBEA_00617	1046629.Ssal_00558	0.0	1271.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
IGHDCBEA_00618	1046629.Ssal_00557	2.83e-124	355.0	COG0546@1|root,COG0546@2|Bacteria,1V421@1239|Firmicutes,4HHYH@91061|Bacilli	91061|Bacilli	S	IA, variant 1	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
IGHDCBEA_00619	904306.HMPREF9192_0878	5.34e-150	423.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes	1239|Firmicutes	M	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
IGHDCBEA_00620	435842.HMPREF0848_01131	5.9e-74	223.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes	1239|Firmicutes	S	Effector of murein hydrolase LrgA	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
IGHDCBEA_00623	515620.EUBELI_20304	1.74e-56	197.0	2BVUB@1|root,346F5@2|Bacteria,1W0DE@1239|Firmicutes,254CG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00624	1046629.Ssal_00550	0.0	1758.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
IGHDCBEA_00625	1114965.Spaf_0545	3.7e-132	375.0	COG4088@1|root,COG4088@2|Bacteria,1UHQN@1239|Firmicutes,4IS6C@91061|Bacilli	91061|Bacilli	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
IGHDCBEA_00626	1046629.Ssal_00548	1.53e-132	375.0	COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	rimL	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
IGHDCBEA_00627	1046629.Ssal_00547	2.11e-139	393.0	COG1853@1|root,COG1853@2|Bacteria,1VENC@1239|Firmicutes,4HQ31@91061|Bacilli	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
IGHDCBEA_00628	1123314.AUIO01000005_gene141	7.23e-18	82.8	COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli	91061|Bacilli	S	Competence protein	coiA	-	-	ko:K06198	-	-	-	-	ko00000	-	-	-	CoiA
IGHDCBEA_00630	322159.STER_0508	9.55e-189	526.0	COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli	91061|Bacilli	S	Transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
IGHDCBEA_00631	1046629.Ssal_01693	3.39e-194	540.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli	91061|Bacilli	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06620	GHMP_kinases_C,GHMP_kinases_N
IGHDCBEA_00632	1046629.Ssal_01694	8.5e-303	826.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli	91061|Bacilli	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06610	ACT,Homoserine_dh,NAD_binding_3
IGHDCBEA_00633	1046629.Ssal_01695	5.39e-194	540.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,4HHC9@91061|Bacilli	91061|Bacilli	G	deacetylase	icaB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
IGHDCBEA_00634	1046629.Ssal_01696	1.4e-261	717.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli	91061|Bacilli	E	acetylornithine aminotransferase	argD	GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
IGHDCBEA_00635	435842.HMPREF0848_00098	7.85e-159	447.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli	91061|Bacilli	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
IGHDCBEA_00636	435842.HMPREF0848_00097	2.23e-280	767.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
IGHDCBEA_00637	1046629.Ssal_01699	8.43e-238	654.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli	91061|Bacilli	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU11190	Semialdhyde_dh,Semialdhyde_dhC
IGHDCBEA_00638	1046629.Ssal_01700	8.22e-290	790.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli	91061|Bacilli	E	mutations do not affect methionine salvage in vivo however	mtnE	-	-	ko:K08969	ko00270,ko01100,map00270,map01100	M00034	R07396	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IGHDCBEA_00639	1046629.Ssal_01701	4.73e-184	511.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli	91061|Bacilli	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	mtnU	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
IGHDCBEA_00640	1046629.Ssal_01703	0.0	2179.0	COG0860@1|root,COG1705@1|root,COG1876@1|root,COG3757@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,COG1876@2|Bacteria,COG3757@2|Bacteria,1V1F7@1239|Firmicutes,4ISN5@91061|Bacilli	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	GBS_Bsp-like,SH3_5,VanY,YSIRK_signal
IGHDCBEA_00642	1046629.Ssal_01705	2.39e-294	806.0	COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4HKY4@91061|Bacilli	91061|Bacilli	T	GHKL domain	-	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5
IGHDCBEA_00643	1046629.Ssal_01706	3.97e-172	480.0	COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes	1239|Firmicutes	KT	response regulator	-	-	-	ko:K07707	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
IGHDCBEA_00645	1046629.Ssal_01708	2.05e-177	494.0	COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes	1239|Firmicutes	KT	response regulator	-	-	-	ko:K07707	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
IGHDCBEA_00646	1046629.Ssal_01709	0.0	1509.0	COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1W25V@1239|Firmicutes,4HGXW@91061|Bacilli	91061|Bacilli	M	GBS Bsp-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	GBS_Bsp-like,Peptidase_C70,SH3_5,YSIRK_signal
IGHDCBEA_00648	889201.HMPREF9422_1357	2.98e-12	71.2	2DFHB@1|root,2ZRUI@2|Bacteria,1W1N9@1239|Firmicutes,4I1TG@91061|Bacilli	889201.HMPREF9422_1357|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00649	1046629.Ssal_01713	9.05e-85	250.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K20342,ko:K20480	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3,TPR_8
IGHDCBEA_00650	1046629.Ssal_00735	0.0	2114.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,NLPC_P60,PG_binding_1
IGHDCBEA_00651	1046629.Ssal_00734	4.8e-103	353.0	COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat	tcdB	-	-	ko:K11063	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
IGHDCBEA_00652	1046629.Ssal_00733	0.0	952.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	tcdB	-	-	ko:K11063	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	CW_binding_1,NLPC_P60,PG_binding_1,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
IGHDCBEA_00653	1046629.Ssal_00732	0.0	1531.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,NLPC_P60,PG_binding_1
IGHDCBEA_00654	1046629.Ssal_00731	2.73e-133	378.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli	91061|Bacilli	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
IGHDCBEA_00655	1046629.Ssal_00730	2.91e-200	555.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,4H9RA@91061|Bacilli	91061|Bacilli	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0005488,GO:0005515,GO:0042802	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
IGHDCBEA_00656	1046629.Ssal_00729	0.0	1476.0	COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat	tcdB	-	-	ko:K11063	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
IGHDCBEA_00657	1046629.Ssal_00728	0.0	1098.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,NLPC_P60,PG_binding_1
IGHDCBEA_00658	1046629.Ssal_00726	0.0	1365.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,NLPC_P60,PG_binding_1
IGHDCBEA_00659	1046629.Ssal_00725	0.0	1823.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,NLPC_P60,PG_binding_1
IGHDCBEA_00661	1046629.Ssal_00722	1.05e-171	480.0	28MHE@1|root,2ZAUA@2|Bacteria,1V3A5@1239|Firmicutes,4HZB2@91061|Bacilli	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
IGHDCBEA_00662	1046629.Ssal_00721	5.04e-298	817.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K18926	-	M00715	-	-	ko00000,ko00002,ko02000	2.A.1.3.30	-	-	MFS_1
IGHDCBEA_00663	1046629.Ssal_00720	5.1e-88	259.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
IGHDCBEA_00664	1046629.Ssal_00719	1.32e-126	360.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli	91061|Bacilli	GK	Maltose O-acetyltransferase	maa	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	CM_2,Hexapep,Hexapep_2,Mac
IGHDCBEA_00665	904306.HMPREF9192_1436	2.14e-78	251.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K10681,ko:K20487	ko02020,ko02024,map02020,map02024	M00468,M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
IGHDCBEA_00666	1095726.HMPREF1116_1842	4.48e-92	276.0	COG0745@1|root,COG0745@2|Bacteria,1V5S4@1239|Firmicutes,4IQ3S@91061|Bacilli	91061|Bacilli	K	Transcriptional regulatory protein, C terminal	nisR	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IGHDCBEA_00668	158787.BSCA_2266	9.05e-17	85.5	2B6YP@1|root,31ZYT@2|Bacteria,2H32T@201174|Actinobacteria,4D1XQ@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00669	1114965.Spaf_1095	1.31e-113	332.0	COG1131@1|root,COG1131@2|Bacteria,1TSUA@1239|Firmicutes,4HEHW@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	AAA_21,ABC_tran
IGHDCBEA_00670	1046629.Ssal_00717	0.0	2608.0	COG3266@1|root,COG4932@1|root,COG3266@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.5.1.28	ko:K01448,ko:K13733,ko:K20276	ko01503,ko02024,ko05100,map01503,map02024,map05100	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	CHU_C,Gram_pos_anchor,MucBP,SLH
IGHDCBEA_00671	1046629.Ssal_00714	0.0	2754.0	COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli	91061|Bacilli	M	KxYKxGKxW signal domain protein	-	GO:0005575,GO:0005576	2.4.1.5	ko:K00689	ko00500,ko02020,map00500,map02020	-	R02120,R06066	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Big_2,CW_binding_1,Glyco_hydro_70
IGHDCBEA_00672	1046629.Ssal_00711	2.92e-153	431.0	COG1737@1|root,COG1737@2|Bacteria,1TX2U@1239|Firmicutes,4HF5T@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
IGHDCBEA_00673	1046629.Ssal_00710	5.02e-29	116.0	COG3210@1|root,COG3210@2|Bacteria,1VJJV@1239|Firmicutes,4HT7X@91061|Bacilli	1239|Firmicutes	U	LPXTG cell wall anchor motif	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,Cohesin,FIVAR,Gram_pos_anchor,SLH
IGHDCBEA_00675	1000588.HMPREF9965_0695	8.14e-123	351.0	2EG6Z@1|root,339YV@2|Bacteria,1VKQ1@1239|Firmicutes,4HSCJ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00676	1114965.Spaf_igr0640	4.78e-68	206.0	2DNH3@1|root,32XGR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
IGHDCBEA_00677	1046629.Ssal_01405	6.51e-248	682.0	COG3093@1|root,COG3093@2|Bacteria,1V0AU@1239|Firmicutes,4HJU0@91061|Bacilli	91061|Bacilli	K	Pfam:DUF955	higA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
IGHDCBEA_00678	1046629.Ssal_01404	9.41e-201	557.0	COG5464@1|root,COG5464@2|Bacteria	2|Bacteria	S	double-stranded DNA endodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IGHDCBEA_00679	1046629.Ssal_01403	0.0	1445.0	COG5373@1|root,COG5434@1|root,COG5373@2|Bacteria,COG5434@2|Bacteria,1W0JP@1239|Firmicutes	1239|Firmicutes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
IGHDCBEA_00680	1046629.Ssal_01401	8.4e-235	646.0	COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK9Z@91061|Bacilli	91061|Bacilli	F	DNA RNA non-specific endonuclease	spd	-	-	ko:K15051	-	-	-	-	ko00000	-	-	-	Endonuclea_NS_2
IGHDCBEA_00681	904306.HMPREF9192_1175	8.87e-120	343.0	COG1704@1|root,COG1704@2|Bacteria,1V1G7@1239|Firmicutes,4IR1J@91061|Bacilli	91061|Bacilli	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
IGHDCBEA_00682	1046629.Ssal_01399	5.7e-188	525.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli	91061|Bacilli	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
IGHDCBEA_00683	435842.HMPREF0848_00373	1.83e-149	421.0	COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HHV4@91061|Bacilli	91061|Bacilli	K	iron dependent repressor	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
IGHDCBEA_00684	435842.HMPREF0848_00374	2.55e-213	590.0	COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli	91061|Bacilli	P	Belongs to the bacterial solute-binding protein 9 family	psaA	-	-	ko:K11704,ko:K19971,ko:K19975,ko:K19976	ko02010,map02010	M00318,M00791,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6	-	-	ZnuA
IGHDCBEA_00685	435842.HMPREF0848_00375	3.33e-170	479.0	COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli	91061|Bacilli	P	ABC-type Mn2 Zn2 transport systems, permease components	mtsC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944	-	ko:K11705,ko:K19972,ko:K19976	ko02010,map02010	M00318,M00791,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6	-	-	ABC-3
IGHDCBEA_00686	1046629.Ssal_01395	9.25e-161	451.0	COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli	91061|Bacilli	P	ABC transporter, ATP-binding protein	sitB	-	3.6.3.35	ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973	ko02010,map02010	M00243,M00244,M00318,M00791,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6	-	-	ABC_tran
IGHDCBEA_00687	1046629.Ssal_01394	9.64e-94	275.0	COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
IGHDCBEA_00688	1046629.Ssal_01392	3.79e-83	246.0	2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
IGHDCBEA_00689	1046629.Ssal_01391	0.0	1823.0	COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli	91061|Bacilli	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
IGHDCBEA_00690	1046629.Ssal_01390	5.47e-236	650.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli	91061|Bacilli	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
IGHDCBEA_00691	1046629.Ssal_01389	1.59e-143	404.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli	91061|Bacilli	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0005575,GO:0005576	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
IGHDCBEA_00692	1046629.Ssal_01388	5.23e-240	669.0	COG2367@1|root,COG2367@2|Bacteria,1VHF8@1239|Firmicutes,4HU1N@91061|Bacilli	91061|Bacilli	V	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
IGHDCBEA_00693	1046629.Ssal_01387	3.14e-147	415.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,4HCC3@91061|Bacilli	91061|Bacilli	NOU	Type II secretory pathway prepilin signal peptidase PulO and related peptidases	comC	-	3.4.23.43	ko:K02236,ko:K02654	-	M00331,M00429	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
IGHDCBEA_00694	1046629.Ssal_01386	1.35e-119	342.0	COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli	91061|Bacilli	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
IGHDCBEA_00695	1046629.Ssal_01385	1.15e-102	297.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli	91061|Bacilli	P	Belongs to the Fur family	perR	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IGHDCBEA_00696	435842.HMPREF0848_00386	7.59e-37	124.0	COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	yqgQ	-	-	-	-	-	-	-	-	-	-	-	DUF910
IGHDCBEA_00697	1046629.Ssal_01383	7.66e-225	620.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli	91061|Bacilli	G	Glucokinase	glcK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07790	ROK
IGHDCBEA_00698	1046629.Ssal_01382	0.0	1191.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli	91061|Bacilli	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
IGHDCBEA_00699	663952.SDD27957_07710	3.66e-12	63.5	2DJ77@1|root,304WT@2|Bacteria,1TXC0@1239|Firmicutes,4I69V@91061|Bacilli,1M9RX@119603|Streptococcus dysgalactiae group	91061|Bacilli	S	Protein of unknown function (DUF3165)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3165
IGHDCBEA_00700	1046629.Ssal_01380	0.0	865.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli	91061|Bacilli	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
IGHDCBEA_00701	1046629.Ssal_01379	6.83e-252	691.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
IGHDCBEA_00702	904306.HMPREF9192_1192	2.57e-186	527.0	COG1589@1|root,COG1589@2|Bacteria,1VHEY@1239|Firmicutes	1239|Firmicutes	D	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex	divIB	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
IGHDCBEA_00703	904306.HMPREF9192_1193	3.51e-308	842.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli	91061|Bacilli	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	DUF3484,FtsA,SHS2_FTSA
IGHDCBEA_00704	1046629.Ssal_01376	1.31e-303	829.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli	91061|Bacilli	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
IGHDCBEA_00705	1046629.Ssal_01375	3.98e-159	446.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli	91061|Bacilli	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
IGHDCBEA_00706	1046629.Ssal_01374	1.21e-130	371.0	COG1799@1|root,COG1799@2|Bacteria	2|Bacteria	D	cell septum assembly	sepF	GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
IGHDCBEA_00707	435842.HMPREF0848_00397	9.29e-40	133.0	COG0762@1|root,COG0762@2|Bacteria	2|Bacteria	D	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
IGHDCBEA_00708	1046629.Ssal_01373	1.89e-186	518.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli	91061|Bacilli	S	conserved protein, contains S4-like domain	ylmH	-	-	-	-	-	-	-	-	-	-	-	S4
IGHDCBEA_00709	1046629.Ssal_01372	2.89e-193	538.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli	91061|Bacilli	D	Cell division initiation protein	divIVA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
IGHDCBEA_00710	1046629.Ssal_01371	0.0	1862.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli	91061|Bacilli	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
IGHDCBEA_00711	904306.HMPREF9192_1446	5.18e-255	702.0	COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli	91061|Bacilli	P	transporter	yycB	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
IGHDCBEA_00712	904306.HMPREF9192_1447	3.39e-191	531.0	COG1307@1|root,COG1307@2|Bacteria,1V229@1239|Firmicutes,4IPK5@91061|Bacilli	91061|Bacilli	S	EDD domain protein, DegV family	ChZ00x2	-	-	-	-	-	-	-	-	-	-	-	DegV
IGHDCBEA_00713	1046629.Ssal_01477	1.91e-123	353.0	COG1309@1|root,COG1309@2|Bacteria,1VGCX@1239|Firmicutes,4HRBM@91061|Bacilli	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IGHDCBEA_00714	888048.HMPREF8577_0787	6.5e-124	354.0	COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli	91061|Bacilli	F	HD superfamily hydrolase	yagB	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
IGHDCBEA_00715	888833.HMPREF9421_1585	5.25e-164	462.0	COG1266@1|root,COG1266@2|Bacteria,1V1I8@1239|Firmicutes	1239|Firmicutes	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IGHDCBEA_00716	1046629.Ssal_01475	5.06e-145	409.0	COG3142@1|root,COG3142@2|Bacteria,1V3V5@1239|Firmicutes,4HCVQ@91061|Bacilli	91061|Bacilli	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
IGHDCBEA_00717	1046629.Ssal_01473	0.0	1157.0	COG1216@1|root,COG1442@1|root,COG1216@2|Bacteria,COG1442@2|Bacteria,1VATJ@1239|Firmicutes,4HG1M@91061|Bacilli	91061|Bacilli	M	family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8,Glycos_transf_2
IGHDCBEA_00718	1046629.Ssal_01523	0.0	892.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4H9V9@91061|Bacilli	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
IGHDCBEA_00719	1046629.Ssal_01470	0.0	1078.0	COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli	91061|Bacilli	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IGHDCBEA_00720	1046629.Ssal_01469	3.02e-124	354.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	tetR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
IGHDCBEA_00721	1046629.Ssal_01468	5.91e-196	543.0	28KEH@1|root,2ZA0R@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4300
IGHDCBEA_00722	1046629.Ssal_01467	1.15e-160	452.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
IGHDCBEA_00723	435842.HMPREF0848_00309	5.66e-208	580.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli	91061|Bacilli	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fecD	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
IGHDCBEA_00724	435842.HMPREF0848_00310	1.6e-170	477.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HETN@91061|Bacilli	91061|Bacilli	HP	ABC transporter	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
IGHDCBEA_00725	435842.HMPREF0848_00311	1.05e-230	636.0	COG0614@1|root,COG0614@2|Bacteria,1TSDG@1239|Firmicutes,4HDG3@91061|Bacilli	91061|Bacilli	P	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component	fatB	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
IGHDCBEA_00726	1046629.Ssal_01463	3.7e-160	449.0	COG2819@1|root,COG2819@2|Bacteria,1V2YF@1239|Firmicutes,4IQ46@91061|Bacilli	91061|Bacilli	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
IGHDCBEA_00727	1316408.HSISM1_1770	9.82e-106	308.0	COG0500@1|root,COG0500@2|Bacteria,1UI83@1239|Firmicutes,4HHCN@91061|Bacilli	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
IGHDCBEA_00728	1123300.AUIN01000009_gene228	7.93e-99	291.0	COG1309@1|root,COG1309@2|Bacteria,1VCGN@1239|Firmicutes,4HMEM@91061|Bacilli	91061|Bacilli	K	TetR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IGHDCBEA_00729	1046629.Ssal_01462	5.4e-63	193.0	2CUT8@1|root,32SW2@2|Bacteria,1VAQK@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00730	1046629.Ssal_01461	1.39e-154	436.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
IGHDCBEA_00732	1005705.HMPREF9967_0252	2.89e-28	108.0	2DIXF@1|root,304BM@2|Bacteria,1TWG1@1239|Firmicutes,4I59C@91061|Bacilli,43G59@68892|Streptococcus infantis	91061|Bacilli	M	Bacterial lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3642
IGHDCBEA_00733	435842.HMPREF0848_00317	1.88e-78	234.0	COG3272@1|root,COG3272@2|Bacteria,1VGGK@1239|Firmicutes,4HP7S@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722
IGHDCBEA_00734	1046629.Ssal_01457	2.89e-84	248.0	2AK1X@1|root,31ARI@2|Bacteria,1V717@1239|Firmicutes,4HIQ9@91061|Bacilli	91061|Bacilli	S	Pyrimidine dimer DNA glycosylase	yqeB	-	-	-	-	-	-	-	-	-	-	-	Pyr_excise
IGHDCBEA_00736	1046629.Ssal_01455	1.07e-67	206.0	2FBVV@1|root,3440F@2|Bacteria,1VZAT@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00737	1046629.Ssal_01454	8.22e-122	350.0	COG1266@1|root,COG1266@2|Bacteria,1VBYM@1239|Firmicutes,4HM2K@91061|Bacilli	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
IGHDCBEA_00738	1046629.Ssal_01453	1.2e-153	431.0	COG2755@1|root,COG2755@2|Bacteria,1V1CQ@1239|Firmicutes,4HGVZ@91061|Bacilli	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IGHDCBEA_00739	1046629.Ssal_01451	2.81e-134	381.0	2F636@1|root,33YMH@2|Bacteria,1VYAW@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00740	1046629.Ssal_01450	0.0	1000.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli	91061|Bacilli	P	Sulfate permease and related transporters (MFS superfamily)	yvdB	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
IGHDCBEA_00741	904306.HMPREF9192_1125	9.79e-191	530.0	COG3689@1|root,COG3689@2|Bacteria,1V3EX@1239|Firmicutes,4HGMG@91061|Bacilli	91061|Bacilli	S	TIGR03943 family	XK27_03010	-	-	ko:K08986	-	-	-	-	ko00000	-	-	-	DUF1980
IGHDCBEA_00742	1046629.Ssal_01448	3.97e-200	556.0	COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli	91061|Bacilli	S	permease	XK27_03015	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
IGHDCBEA_00744	1046629.Ssal_01446	0.0	1324.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli	91061|Bacilli	K	Transcriptional accessory protein	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
IGHDCBEA_00745	1046629.Ssal_01444	1.02e-55	173.0	COG1983@1|root,COG1983@2|Bacteria,1VF0M@1239|Firmicutes,4IRAN@91061|Bacilli	91061|Bacilli	KT	PspC domain	WQ51_05770	-	-	-	-	-	-	-	-	-	-	-	PspC
IGHDCBEA_00746	1046629.Ssal_01443	1.4e-209	580.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli	91061|Bacilli	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
IGHDCBEA_00747	1046629.Ssal_01442	1.69e-187	521.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli	91061|Bacilli	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
IGHDCBEA_00748	904306.HMPREF9192_1133	9.98e-28	106.0	COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli	91061|Bacilli	S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain	ytxG	-	-	-	-	-	-	-	-	-	-	-	DUF948
IGHDCBEA_00749	1046629.Ssal_01439	6.48e-89	262.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli	91061|Bacilli	S	General stress protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
IGHDCBEA_00751	1046629.Ssal_00697	1.92e-78	263.0	COG5295@1|root,COG5295@2|Bacteria,1VIS5@1239|Firmicutes	1239|Firmicutes	UW	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,Gram_pos_anchor,Rib
IGHDCBEA_00752	1046629.Ssal_00703	3.79e-45	162.0	COG2373@1|root,COG3203@1|root,COG2373@2|Bacteria,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,FG-GAP_2,OprB,Porin_4,SLH
IGHDCBEA_00753	585203.SMSK564_1819	1.59e-17	76.3	2DKDD@1|root,3097M@2|Bacteria,1U4K0@1239|Firmicutes,4IEBR@91061|Bacilli,2TQ0I@28037|Streptococcus mitis	91061|Bacilli	S	Accessory secretory protein Sec, Asp5	-	-	-	-	-	-	-	-	-	-	-	-	Asp5
IGHDCBEA_00754	888049.HMPREF8578_0919	8.08e-16	70.9	2DJ42@1|root,304Q9@2|Bacteria,1TX0H@1239|Firmicutes,4I5VE@91061|Bacilli,1WPZZ@1303|Streptococcus oralis	91061|Bacilli	S	Accessory secretory protein Sec Asp4	-	-	-	-	-	-	-	-	-	-	-	-	Asp4
IGHDCBEA_00755	1046629.Ssal_00696	0.0	1540.0	COG0653@1|root,COG0653@2|Bacteria,1TRJA@1239|Firmicutes,4HCH0@91061|Bacilli	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA2	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
IGHDCBEA_00756	1046629.Ssal_00695	3.8e-90	265.0	2AFSZ@1|root,315V3@2|Bacteria,1V6D1@1239|Firmicutes,4HS4W@91061|Bacilli	91061|Bacilli	S	Accessory Sec system protein Asp3	asp3	-	-	ko:K12270	-	-	-	-	ko00000,ko02044	3.A.5.10	-	-	Sec-ASP3
IGHDCBEA_00757	1046629.Ssal_00694	0.0	1032.0	COG1073@1|root,COG1073@2|Bacteria,1TSWW@1239|Firmicutes,4HB1I@91061|Bacilli	91061|Bacilli	S	Accessory Sec system protein Asp2	asp2	-	-	ko:K12269	-	-	-	-	ko00000,ko02044	3.A.5.10	-	-	Asp2
IGHDCBEA_00758	1046629.Ssal_00693	0.0	1063.0	2CI7G@1|root,2ZBRM@2|Bacteria,1V1BC@1239|Firmicutes,4HKRQ@91061|Bacilli	91061|Bacilli	S	Accessory Sec system protein Asp1	asp1	-	-	ko:K12268	-	-	-	-	ko00000,ko02044	3.A.5.10	-	-	Asp1
IGHDCBEA_00759	888833.HMPREF9421_0584	8.5e-208	583.0	COG0201@1|root,COG0201@2|Bacteria,1V59T@1239|Firmicutes,4HH1U@91061|Bacilli	91061|Bacilli	U	Part of the accessory SecA2 SecY2 system specifically required for export of	secY2	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
IGHDCBEA_00760	1046629.Ssal_00690	4.94e-308	838.0	COG1442@1|root,COG1442@2|Bacteria,1UY89@1239|Firmicutes	1239|Firmicutes	M	family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
IGHDCBEA_00761	888833.HMPREF9421_0582	0.0	1551.0	COG1442@1|root,COG1442@2|Bacteria,1V3ET@1239|Firmicutes,4ITEW@91061|Bacilli	91061|Bacilli	M	cog cog1442	-	-	-	-	-	-	-	-	-	-	-	-	GT-D,Glyco_transf_8
IGHDCBEA_00762	1046629.Ssal_00687	3.89e-214	591.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase group 2 family protein	cpsJ	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IGHDCBEA_00763	1046629.Ssal_00686	4.56e-299	815.0	COG1442@1|root,COG1442@2|Bacteria,1VJHX@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase, family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
IGHDCBEA_00764	1046629.Ssal_00685	4.78e-237	652.0	COG0438@1|root,COG0438@2|Bacteria,1V6NM@1239|Firmicutes,4HISP@91061|Bacilli	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00765	888833.HMPREF9421_0579	1.24e-242	672.0	COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes	1239|Firmicutes	M	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00766	1046629.Ssal_00683	0.0	1003.0	COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli	91061|Bacilli	M	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon	gtf1	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
IGHDCBEA_00767	1046629.Ssal_00682	5.04e-54	179.0	COG1442@1|root,COG1442@2|Bacteria,1VJHX@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase, family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
IGHDCBEA_00768	1046629.Ssal_00682	8.14e-204	570.0	COG1442@1|root,COG1442@2|Bacteria,1VJHX@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase, family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
IGHDCBEA_00769	1046629.Ssal_00681	3.57e-203	563.0	COG0110@1|root,COG1216@1|root,COG0110@2|Bacteria,COG1216@2|Bacteria,1V1SM@1239|Firmicutes,4HFTP@91061|Bacilli	91061|Bacilli	S	acetyltransferase'	yvoF	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
IGHDCBEA_00770	1046629.Ssal_00680	0.0	1394.0	COG1216@1|root,COG1442@1|root,COG1216@2|Bacteria,COG1442@2|Bacteria,1VATJ@1239|Firmicutes,4HG1M@91061|Bacilli	91061|Bacilli	M	family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8,Glycos_transf_2
IGHDCBEA_00771	1046629.Ssal_00679	6.08e-202	560.0	COG0110@1|root,COG0110@2|Bacteria,1TPKX@1239|Firmicutes,4HEHH@91061|Bacilli	91061|Bacilli	S	acetyltransferase'	vatD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008374,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044444,GO:0044464	2.3.1.28,2.3.1.79	ko:K00638,ko:K00661,ko:K18234	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Hexapep
IGHDCBEA_00775	1046629.Ssal_01135	0.0	1103.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli	91061|Bacilli	C	Dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
IGHDCBEA_00776	1046629.Ssal_01136	5.38e-273	753.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	acoC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
IGHDCBEA_00777	1046629.Ssal_01137	1.14e-231	638.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli	91061|Bacilli	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	acoB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
IGHDCBEA_00778	1046629.Ssal_01138	4.34e-236	649.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli	91061|Bacilli	C	Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
IGHDCBEA_00779	1046629.Ssal_01139	2.55e-275	755.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	hpk9	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5,PAS_9
IGHDCBEA_00780	1046629.Ssal_01140	3.75e-286	784.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HATPase_c_5,HD,HD_5,HisKA_3,MASE3,PAS,PAS_3,PAS_4,PAS_9,dCache_3
IGHDCBEA_00781	1046629.Ssal_01151	0.0	1201.0	COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,4HF7D@91061|Bacilli	91061|Bacilli	S	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
IGHDCBEA_00782	1046629.Ssal_01152	5.94e-300	818.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli	91061|Bacilli	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
IGHDCBEA_00783	904306.HMPREF9192_1707	6.38e-151	424.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli	91061|Bacilli	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
IGHDCBEA_00784	1046629.Ssal_01154	6.63e-278	761.0	COG0053@1|root,COG4994@1|root,COG0053@2|Bacteria,COG4994@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli	91061|Bacilli	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	yeaB	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
IGHDCBEA_00785	1046629.Ssal_01155	2.78e-316	862.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HD0P@91061|Bacilli	91061|Bacilli	M	Belongs to the peptidase S11 family	dacA1	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	DUF1958,Peptidase_S11
IGHDCBEA_00786	1046629.Ssal_01155	5.6e-152	441.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HD0P@91061|Bacilli	91061|Bacilli	M	Belongs to the peptidase S11 family	dacA1	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	DUF1958,Peptidase_S11
IGHDCBEA_00787	1046629.Ssal_01156	8.75e-200	553.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli	91061|Bacilli	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
IGHDCBEA_00788	1046629.Ssal_01157	1.32e-131	374.0	COG2755@1|root,COG2755@2|Bacteria,1VHUN@1239|Firmicutes,4IPN1@91061|Bacilli	91061|Bacilli	E	Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
IGHDCBEA_00789	1046629.Ssal_01158	0.0	984.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli	91061|Bacilli	S	unusual protein kinase	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
IGHDCBEA_00790	1046629.Ssal_01159	2.35e-52	165.0	COG3937@1|root,COG3937@2|Bacteria,1VK6K@1239|Firmicutes,4HRS5@91061|Bacilli	91061|Bacilli	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00791	1046629.Ssal_01160	0.0	972.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	bglA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
IGHDCBEA_00792	1046629.Ssal_01161	2.66e-251	692.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,4HGFS@91061|Bacilli	91061|Bacilli	S	hmm pf01594	XK27_12525	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
IGHDCBEA_00793	1046629.Ssal_01162	4.47e-138	390.0	COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli	91061|Bacilli	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IGHDCBEA_00794	904306.HMPREF9192_1693	2.62e-138	391.0	COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli	91061|Bacilli	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IGHDCBEA_00795	1046629.Ssal_01164	9.32e-139	392.0	COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli	91061|Bacilli	G	Belongs to the phosphoglycerate mutase family	XK27_06100	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IGHDCBEA_00796	1046629.Ssal_01165	1.06e-190	530.0	COG0561@1|root,COG0561@2|Bacteria,1V1SQ@1239|Firmicutes,4IPTG@91061|Bacilli	91061|Bacilli	S	Sucrose-6F-phosphate phosphohydrolase	supH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IGHDCBEA_00797	1046629.Ssal_00134	2.99e-247	678.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli	91061|Bacilli	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
IGHDCBEA_00798	904306.HMPREF9192_2002	7.09e-101	293.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,4HDY5@91061|Bacilli	91061|Bacilli	E	Acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ACT,ACT_5,ALS_ss_C
IGHDCBEA_00799	1046629.Ssal_00132	0.0	1100.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli	91061|Bacilli	EH	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	iYO844.BSU28310	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
IGHDCBEA_00800	1046629.Ssal_00131	0.0	1133.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli	91061|Bacilli	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ILVD_EDD
IGHDCBEA_00801	1046629.Ssal_00130	0.0	1051.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli	91061|Bacilli	S	kinase related to dihydroxyacetone kinase	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
IGHDCBEA_00802	1046629.Ssal_00129	1.87e-76	228.0	COG1302@1|root,COG1302@2|Bacteria,1V3Q6@1239|Firmicutes,4HHYJ@91061|Bacilli	91061|Bacilli	S	cog cog1302	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
IGHDCBEA_00803	1046629.Ssal_00128	5.74e-285	781.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli	91061|Bacilli	V	Mate efflux family protein	norN	-	-	-	-	-	-	-	-	-	-	-	MatE
IGHDCBEA_00804	1046629.Ssal_00127	0.0	961.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli	91061|Bacilli	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
IGHDCBEA_00805	435842.HMPREF0848_01381	6.92e-05	52.8	COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli	91061|Bacilli	M	Membrane	yebC	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3,zinc_ribbon_2
IGHDCBEA_00807	1046629.Ssal_00122	0.0	1693.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli	91061|Bacilli	C	belongs to the iron- containing alcohol dehydrogenase family	adh	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00885	Aldedh,Fe-ADH
IGHDCBEA_00808	435842.HMPREF0848_01786	0.0	1247.0	COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli	91061|Bacilli	O	Peptidase family M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
IGHDCBEA_00809	1046629.Ssal_00120	0.0	1125.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli	91061|Bacilli	G	COG0366 Glycosidases	treC	-	3.2.1.93	ko:K01226	ko00500,map00500	-	R00837,R06113	RC00049	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
IGHDCBEA_00810	1046629.Ssal_00119	0.0	1255.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli	91061|Bacilli	G	pts system	treP	-	2.7.1.201	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	M00270	R02780	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.13,4.A.1.2.4,4.A.1.2.8	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
IGHDCBEA_00811	904306.HMPREF9192_1990	3.52e-162	454.0	COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli	91061|Bacilli	K	trehalose operon	treR	-	-	ko:K03486	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
IGHDCBEA_00812	904306.HMPREF9192_1989	9.24e-122	348.0	COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0340 family	ywlG	-	-	-	-	-	-	-	-	-	-	-	DUF436
IGHDCBEA_00815	1046629.Ssal_00114	4.93e-211	583.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli	91061|Bacilli	G	aldolase	fba	-	4.1.2.13,4.1.2.29	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568,R05378	RC00438,RC00439,RC00603,RC00604,RC00721	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
IGHDCBEA_00817	1046629.Ssal_00112	7.24e-301	822.0	COG3572@1|root,COG3572@2|Bacteria,1TW3D@1239|Firmicutes,4HTV4@91061|Bacilli	91061|Bacilli	H	gamma-glutamylcysteine synthetase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
IGHDCBEA_00818	1046629.Ssal_02145	3.84e-278	761.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli	91061|Bacilli	E	Aminotransferase	araT	-	-	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R04467	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IGHDCBEA_00819	1046629.Ssal_02144	9.74e-182	506.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli	91061|Bacilli	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
IGHDCBEA_00820	1046629.Ssal_02143	1.97e-233	644.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli	91061|Bacilli	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
IGHDCBEA_00821	1046629.Ssal_02142	6.59e-41	135.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP_1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
IGHDCBEA_00822	1046629.Ssal_02141	5.24e-168	469.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli	91061|Bacilli	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
IGHDCBEA_00823	1046629.Ssal_02140	0.0	2413.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
IGHDCBEA_00824	1282664.H354_08670	6.37e-223	618.0	28Q4T@1|root,2ZCMX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00825	1046629.Ssal_02139	0.0	952.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli	91061|Bacilli	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
IGHDCBEA_00826	435842.HMPREF0848_01955	3.74e-241	663.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli	91061|Bacilli	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
IGHDCBEA_00827	1046629.Ssal_02137	5.7e-129	366.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli	91061|Bacilli	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
IGHDCBEA_00828	35841.BT1A1_0854	4.22e-46	155.0	2E4E5@1|root,32Z9D@2|Bacteria,1VUIW@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00829	1046629.Ssal_02136	0.0	1015.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli	91061|Bacilli	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
IGHDCBEA_00830	435842.HMPREF0848_01948	3.89e-304	829.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli	91061|Bacilli	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
IGHDCBEA_00831	1005705.HMPREF9967_0320	6.76e-106	306.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,43FX6@68892|Streptococcus infantis	91061|Bacilli	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
IGHDCBEA_00832	904306.HMPREF9192_0016	5.45e-257	705.0	COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli	91061|Bacilli	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
IGHDCBEA_00833	1316408.HSISM1_690	4.81e-225	620.0	COG1893@1|root,COG1893@2|Bacteria,1UD8U@1239|Firmicutes	1239|Firmicutes	H	Ketopantoate reductase	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA
IGHDCBEA_00834	904306.HMPREF9192_0018	1.81e-45	147.0	2DZH9@1|root,32VAR@2|Bacteria,1VIUY@1239|Firmicutes,4HZSZ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00835	1203590.HMPREF1481_01503	1.31e-184	526.0	COG0172@1|root,COG0172@2|Bacteria,1TPSA@1239|Firmicutes,4H9M2@91061|Bacilli	91061|Bacilli	J	Domain of unknown function (DUF4041)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4041,MUG113,T5orf172
IGHDCBEA_00837	264199.stu0045	3.03e-314	855.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli	91061|Bacilli	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09895	ADSL_C,Lyase_1
IGHDCBEA_00838	1046629.Ssal_02030	0.0	1571.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	cpdB	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Gram_pos_anchor,Metallophos,SLH
IGHDCBEA_00840	563038.HMPREF0851_01097	8.54e-134	381.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,HTH_7,Resolvase,Sigma70_r4_2
IGHDCBEA_00844	1214184.ALKY01000022_gene689	2.41e-27	102.0	2B43I@1|root,31WU1@2|Bacteria,1U9AC@1239|Firmicutes,4IJD0@91061|Bacilli,1WU42@1307|Streptococcus suis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00847	563038.HMPREF0851_02089	0.0	1357.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87,TraG-D_C,TrwB_AAD_bind
IGHDCBEA_00848	563038.HMPREF0851_02088	3.23e-178	498.0	2DM9G@1|root,328GS@2|Bacteria,1VWN6@1239|Firmicutes	1239|Firmicutes	S	Replication-relaxation	-	-	-	-	-	-	-	-	-	-	-	-	Replic_Relax
IGHDCBEA_00850	1302863.I872_06440	0.0	1033.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HCQ7@91061|Bacilli	91061|Bacilli	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
IGHDCBEA_00851	1046629.Ssal_02029	6.05e-109	313.0	COG1780@1|root,COG1780@2|Bacteria,1V71V@1239|Firmicutes,4HIW7@91061|Bacilli	91061|Bacilli	F	Belongs to the NrdI family	nrdI	-	-	ko:K03647	-	-	-	-	ko00000	-	-	-	Flavodoxin_NdrI
IGHDCBEA_00852	1046629.Ssal_02028	0.0	1444.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
IGHDCBEA_00853	1046629.Ssal_02026	5.78e-97	282.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
IGHDCBEA_00854	1046629.Ssal_02025	0.0	1920.0	COG5297@1|root,COG5297@2|Bacteria,1TS2G@1239|Firmicutes,4HF5J@91061|Bacilli	91061|Bacilli	G	Glycosyl hydrolase family 66	dex	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	CBM_35,Glyco_hydro_66,Gram_pos_anchor,SLH
IGHDCBEA_00855	1046629.Ssal_02023	3.18e-301	821.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli	91061|Bacilli	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
IGHDCBEA_00856	904306.HMPREF9192_0243	5.97e-145	408.0	COG0242@1|root,COG0242@2|Bacteria,1V5C6@1239|Firmicutes,4HGUI@91061|Bacilli	91061|Bacilli	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IGHDCBEA_00857	1046629.Ssal_02021	6.64e-146	411.0	COG0664@1|root,COG0664@2|Bacteria,1V2AH@1239|Firmicutes,4HFNC@91061|Bacilli	91061|Bacilli	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
IGHDCBEA_00858	1046629.Ssal_02020	1.4e-245	678.0	COG2807@1|root,COG2807@2|Bacteria,1TSM5@1239|Firmicutes,4HF98@91061|Bacilli	91061|Bacilli	P	Major Facilitator	XK27_00055	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IGHDCBEA_00859	1046629.Ssal_02019	3.52e-57	177.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli	91061|Bacilli	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
IGHDCBEA_00860	1046629.Ssal_02018	6.41e-127	362.0	COG4767@1|root,COG4767@2|Bacteria,1VM0K@1239|Firmicutes,4HVBZ@91061|Bacilli	91061|Bacilli	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
IGHDCBEA_00861	1046629.Ssal_02017	0.0	941.0	COG1196@1|root,COG1196@2|Bacteria,1VXI0@1239|Firmicutes,4HMHC@91061|Bacilli	91061|Bacilli	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
IGHDCBEA_00862	904306.HMPREF9192_0239	4.26e-168	470.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	glnQ	-	-	ko:K17076	ko02010,map02010	M00589	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.20	-	-	ABC_tran
IGHDCBEA_00863	1046629.Ssal_02015	0.0	968.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli	91061|Bacilli	P	ABC transporter	XK27_05795	-	-	ko:K17073,ko:K17074	ko02010,map02010	M00589	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.20	-	-	BPD_transp_1,SBP_bac_3
IGHDCBEA_00864	1046629.Ssal_02014	1.75e-195	543.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli	91061|Bacilli	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
IGHDCBEA_00866	1046629.Ssal_02012	2.1e-165	464.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli	91061|Bacilli	NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis	mecA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
IGHDCBEA_00867	1046629.Ssal_02011	2.21e-242	670.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli	91061|Bacilli	M	transferase	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
IGHDCBEA_00868	1046629.Ssal_02010	1.65e-176	493.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli	91061|Bacilli	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
IGHDCBEA_00869	1046629.Ssal_02009	5.93e-299	816.0	COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli	91061|Bacilli	O	assembly protein SufD	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
IGHDCBEA_00870	1046629.Ssal_02008	6.11e-296	807.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli	91061|Bacilli	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
IGHDCBEA_00871	904306.HMPREF9192_0231	2.48e-96	280.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli	91061|Bacilli	C	SUF system FeS assembly protein, NifU family	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
IGHDCBEA_00872	904306.HMPREF9192_0230	0.0	945.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli	91061|Bacilli	O	assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
IGHDCBEA_00873	1046629.Ssal_02004	0.0	1080.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli	91061|Bacilli	E	ABC transporter substrate-binding protein	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
IGHDCBEA_00874	435842.HMPREF0848_01502	2.5e-205	569.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli	91061|Bacilli	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
IGHDCBEA_00875	1046629.Ssal_02002	1.36e-224	621.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli	91061|Bacilli	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
IGHDCBEA_00876	1046629.Ssal_02001	1.55e-252	692.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
IGHDCBEA_00877	1046629.Ssal_01999	1.36e-219	606.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
IGHDCBEA_00878	1123311.KB904471_gene1168	3.52e-34	121.0	2DCPN@1|root,2ZEV1@2|Bacteria,1W24H@1239|Firmicutes,4HZKX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00879	1046629.Ssal_01995	1.57e-200	556.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli	91061|Bacilli	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
IGHDCBEA_00880	435842.HMPREF0848_01508	5.66e-232	639.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
IGHDCBEA_00881	1046629.Ssal_01993	5.02e-92	270.0	COG1846@1|root,COG1846@2|Bacteria,1VXZT@1239|Firmicutes,4HXMU@91061|Bacilli	91061|Bacilli	K	transcriptional	adcR	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
IGHDCBEA_00882	1046629.Ssal_01992	9.82e-173	481.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli	91061|Bacilli	P	ABC transporter, ATP-binding protein	adcC	-	-	ko:K02074,ko:K09817	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	iYO844.BSU02860	ABC_tran
IGHDCBEA_00883	904306.HMPREF9192_0223	8.57e-164	461.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	adcB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
IGHDCBEA_00884	435842.HMPREF0848_01512	1.22e-200	558.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli	91061|Bacilli	S	Transporter, auxin efflux carrier (AEC) family protein	mleP2	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
IGHDCBEA_00885	1046629.Ssal_01989	0.0	1355.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli	91061|Bacilli	G	pts system	ptsG	-	2.7.1.208	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.11,4.A.1.1.12	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
IGHDCBEA_00886	1046629.Ssal_01988	1.95e-200	555.0	COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,4HGS5@91061|Bacilli	91061|Bacilli	L	Endonuclease/Exonuclease/phosphatase family	rgfB	-	3.1.3.90	ko:K06896	ko00500,map00500	-	R10486	RC00017	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
IGHDCBEA_00887	1046629.Ssal_01987	0.0	885.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli	91061|Bacilli	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
IGHDCBEA_00888	1046629.Ssal_01986	5.16e-191	532.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	Z012_04635	-	-	ko:K20373	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_3,HTH_31
IGHDCBEA_00889	1046629.Ssal_01985	0.0	930.0	COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli	91061|Bacilli	V	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_00890	1046629.Ssal_01984	2.37e-161	452.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli	91061|Bacilli	K	transcriptional regulatory protein	yeeN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
IGHDCBEA_00891	1046629.Ssal_01983	4.14e-63	194.0	COG1862@1|root,COG1862@2|Bacteria	2|Bacteria	U	protein transport	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
IGHDCBEA_00892	1046629.Ssal_01982	3.56e-182	506.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli	91061|Bacilli	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
IGHDCBEA_00893	1046629.Ssal_01981	5.02e-185	514.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli	91061|Bacilli	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
IGHDCBEA_00894	1046629.Ssal_01980	2.88e-290	794.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli	91061|Bacilli	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
IGHDCBEA_00895	1046629.Ssal_01979	0.0	1189.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
IGHDCBEA_00896	1046629.Ssal_01978	0.0	1155.0	COG2984@1|root,COG4120@1|root,COG2984@2|Bacteria,COG4120@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli	91061|Bacilli	S	ABC transporter	XK27_00665	-	-	ko:K01989,ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
IGHDCBEA_00897	1046629.Ssal_01977	6.07e-183	509.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	cmpC	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
IGHDCBEA_00898	1046629.Ssal_01975	7.72e-57	177.0	COG0234@1|root,COG0234@2|Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
IGHDCBEA_00899	1046629.Ssal_01974	0.0	990.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli	91061|Bacilli	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
IGHDCBEA_00901	435842.HMPREF0848_01529	4.19e-60	186.0	2C0H5@1|root,2ZRTJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
IGHDCBEA_00902	1046629.Ssal_01971	5.41e-73	219.0	COG2314@1|root,COG2314@2|Bacteria,1VKEZ@1239|Firmicutes,4HS74@91061|Bacilli	91061|Bacilli	S	TM2 domain	WQ51_06355	-	-	-	-	-	-	-	-	-	-	-	TM2
IGHDCBEA_00903	1046629.Ssal_01970	1.84e-204	566.0	COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
IGHDCBEA_00904	1046629.Ssal_01969	0.0	1488.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli	91061|Bacilli	M	penicillin-binding protein	pbp2A	-	2.4.1.129,3.4.16.4	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
IGHDCBEA_00905	936154.STP_1748	2.73e-28	101.0	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
IGHDCBEA_00906	904306.HMPREF9192_0204	1.05e-33	115.0	COG0690@1|root,COG0690@2|Bacteria,1W4QH@1239|Firmicutes	1239|Firmicutes	U	Belongs to the SecE SEC61-gamma family	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
IGHDCBEA_00907	1046629.Ssal_01967	2.8e-124	354.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli	91061|Bacilli	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
IGHDCBEA_00908	904306.HMPREF9192_0202	3.06e-88	260.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
IGHDCBEA_00909	1046629.Ssal_01964	2.3e-188	523.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HK1G@91061|Bacilli	91061|Bacilli	S	Sucrose-6F-phosphate phosphohydrolase	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IGHDCBEA_00910	1046629.Ssal_01963	2.04e-175	489.0	COG1349@1|root,COG1349@2|Bacteria,1V6VV@1239|Firmicutes,4HK1E@91061|Bacilli	91061|Bacilli	K	transcriptional regulator (DeoR family)	-	-	-	ko:K22103	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
IGHDCBEA_00911	1046629.Ssal_01962	0.0	1692.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
IGHDCBEA_00912	1046629.Ssal_01960	7.8e-97	282.0	COG1846@1|root,COG1846@2|Bacteria,1V1U2@1239|Firmicutes,4HI88@91061|Bacilli	91061|Bacilli	K	transcriptional	napB	-	-	-	-	-	-	-	-	-	-	-	MarR
IGHDCBEA_00913	1046629.Ssal_01959	9.45e-300	817.0	COG1073@1|root,COG1073@2|Bacteria,1V38K@1239|Firmicutes,4HE7V@91061|Bacilli	91061|Bacilli	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Bile_Hydr_Trans
IGHDCBEA_00914	1046629.Ssal_01958	9.06e-62	192.0	28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,4HMY0@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF2992)	yjdF3	-	-	-	-	-	-	-	-	-	-	-	DUF2992
IGHDCBEA_00915	435842.HMPREF0848_01541	2.06e-21	85.9	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	YCII
IGHDCBEA_00916	1046629.Ssal_01957	4.43e-191	532.0	COG1131@1|root,COG1131@2|Bacteria,1V0AH@1239|Firmicutes,4HD15@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	cylA	-	-	ko:K11050	ko02010,map02010	M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.130	-	-	ABC_tran
IGHDCBEA_00917	1046629.Ssal_01956	5.95e-173	484.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,4HFNX@91061|Bacilli	91061|Bacilli	V	ABC-2 type transporter	cylB	-	-	ko:K11051	ko02010,map02010	M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
IGHDCBEA_00918	1046629.Ssal_01955	2.83e-99	288.0	COG3279@1|root,COG3279@2|Bacteria,1VFKH@1239|Firmicutes,4HQ50@91061|Bacilli	91061|Bacilli	K	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR
IGHDCBEA_00919	585203.SMSK564_0811	4.74e-42	143.0	2DKBP@1|root,30949@2|Bacteria,1U4EH@1239|Firmicutes,4IE74@91061|Bacilli,2TPSA@28037|Streptococcus mitis	91061|Bacilli	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
IGHDCBEA_00920	435842.HMPREF0848_01547	1.08e-156	441.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli	91061|Bacilli	K	Transcriptional	mta	-	-	ko:K21743	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TipAS
IGHDCBEA_00921	1046629.Ssal_01952	1.82e-155	437.0	COG1136@1|root,COG1136@2|Bacteria,1V50G@1239|Firmicutes,4HIB8@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
IGHDCBEA_00922	1046629.Ssal_01951	6.52e-270	743.0	COG0577@1|root,COG0577@2|Bacteria,1VU6Y@1239|Firmicutes,4HT9M@91061|Bacilli	91061|Bacilli	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
IGHDCBEA_00923	1046629.Ssal_01950	0.0	940.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli	91061|Bacilli	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
IGHDCBEA_00924	904306.HMPREF9192_0172	1.97e-191	531.0	COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli	91061|Bacilli	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
IGHDCBEA_00925	264199.stu0228	4.07e-92	270.0	COG3152@1|root,COG3152@2|Bacteria	2|Bacteria	L	Membrane	yhaI	-	-	-	-	-	-	-	-	-	-	-	DUF805
IGHDCBEA_00926	904306.HMPREF9192_0170	0.0	876.0	COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli	91061|Bacilli	E	aminopeptidase	pepC	GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1_2
IGHDCBEA_00927	1046629.Ssal_01944	0.0	1442.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli	91061|Bacilli	M	penicillin-binding protein	ponA	GO:0005575,GO:0005576	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,fn3
IGHDCBEA_00928	1046629.Ssal_01943	1.41e-140	397.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli	91061|Bacilli	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
IGHDCBEA_00929	1046629.Ssal_01942	2.95e-122	348.0	COG4474@1|root,COG4474@2|Bacteria,1V5Q7@1239|Firmicutes,4HECZ@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0398 family	ypsA	-	-	-	-	-	-	-	-	-	-	-	DUF1273
IGHDCBEA_00930	1046629.Ssal_01941	3.97e-66	201.0	COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli	91061|Bacilli	D	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation	gpsB	-	-	-	-	-	-	-	-	-	-	-	DivIVA
IGHDCBEA_00931	1046629.Ssal_01940	2.62e-284	776.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli	91061|Bacilli	L	Belongs to the methyltransferase superfamily	ypsC	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
IGHDCBEA_00932	1046629.Ssal_01939	0.0	1048.0	2DB6P@1|root,32TWV@2|Bacteria,1VDPS@1239|Firmicutes,4HK8Y@91061|Bacilli	91061|Bacilli	D	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning	mapZ	-	-	ko:K20073	-	-	-	-	ko00000	-	-	-	-
IGHDCBEA_00933	1046629.Ssal_01938	0.0	2033.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli	91061|Bacilli	L	Superfamily II DNA RNA helicases, SNF2 family'	snf	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
IGHDCBEA_00934	1214166.ALLG01000002_gene1746	4.8e-28	113.0	2BTGZ@1|root,32NPB@2|Bacteria,1U91J@1239|Firmicutes,4IJ1N@91061|Bacilli,1WTEE@1307|Streptococcus suis	91061|Bacilli	-	-	XK27_11680	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00935	1046629.Ssal_01936	0.0	887.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli	91061|Bacilli	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IGHDCBEA_00936	1046629.Ssal_01935	2.19e-116	333.0	COG0454@1|root,COG0454@2|Bacteria,1VB76@1239|Firmicutes,4HM71@91061|Bacilli	91061|Bacilli	K	histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IGHDCBEA_00937	1046629.Ssal_01934	0.0	1154.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli	91061|Bacilli	ADL	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
IGHDCBEA_00938	1046629.Ssal_01933	1.17e-100	293.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
IGHDCBEA_00939	1046629.Ssal_01931	9.19e-213	588.0	COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli	91061|Bacilli	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
IGHDCBEA_00940	1046629.Ssal_01930	1.35e-60	186.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli	91061|Bacilli	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07020	Acylphosphatase
IGHDCBEA_00941	1046629.Ssal_01929	2.67e-166	466.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
IGHDCBEA_00942	1046629.Ssal_01928	6.25e-122	347.0	COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli	91061|Bacilli	S	HD superfamily hydrolase	XK27_09705	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
IGHDCBEA_00943	1046629.Ssal_01927	4.03e-144	408.0	COG0670@1|root,COG0670@2|Bacteria,1V779@1239|Firmicutes,4HIX1@91061|Bacilli	91061|Bacilli	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
IGHDCBEA_00945	1046629.Ssal_01925	4.07e-310	844.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli	91061|Bacilli	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
IGHDCBEA_00946	1046629.Ssal_01924	3.12e-117	336.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IGHDCBEA_00947	1046629.Ssal_01923	2.31e-48	154.0	COG3763@1|root,COG3763@2|Bacteria,1VDSU@1239|Firmicutes,4HM8G@91061|Bacilli	91061|Bacilli	S	UPF0154 protein	-	-	-	ko:K09976	-	-	-	-	ko00000	-	-	-	UPF0154
IGHDCBEA_00948	1046629.Ssal_01922	2.92e-192	533.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli	91061|Bacilli	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	3.6.1.66,5.1.1.3	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	-	R00260,R00426,R00720,R01855,R02100,R02720,R03531	RC00002,RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU28390	Asp_Glu_race
IGHDCBEA_00949	1046629.Ssal_01921	6.39e-234	643.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli	91061|Bacilli	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
IGHDCBEA_00950	904306.HMPREF9192_0139	6.43e-127	360.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli	91061|Bacilli	S	Phosphoesterase	ysnB	GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
IGHDCBEA_00951	1046629.Ssal_01919	1.81e-113	325.0	COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli	91061|Bacilli	S	CBS domain	ykuL	-	-	-	-	-	-	-	-	-	-	-	CBS
IGHDCBEA_00952	1046629.Ssal_01918	2.57e-169	474.0	COG4974@1|root,COG4974@2|Bacteria,1VY7C@1239|Firmicutes,4IT0W@91061|Bacilli	91061|Bacilli	L	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site	xerD	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
IGHDCBEA_00953	904306.HMPREF9192_0136	8.23e-157	441.0	COG1354@1|root,COG1354@2|Bacteria,1V8JV@1239|Firmicutes,4IQZ5@91061|Bacilli	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
IGHDCBEA_00954	904306.HMPREF9192_0135	1.15e-123	353.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
IGHDCBEA_00955	1046629.Ssal_01915	1.01e-168	471.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IGHDCBEA_00956	1046629.Ssal_01914	9.94e-20	79.3	COG0759@1|root,COG0759@2|Bacteria	2|Bacteria	M	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
IGHDCBEA_00957	1046629.Ssal_01912	0.0	903.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,4HCWN@91061|Bacilli	91061|Bacilli	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
IGHDCBEA_00958	1046629.Ssal_01911	2.31e-313	855.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,4HCRM@91061|Bacilli	91061|Bacilli	P	Potassium transporter peripheral membrane component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
IGHDCBEA_00959	1046629.Ssal_01910	1.53e-123	351.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	cspR	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
IGHDCBEA_00960	1046629.Ssal_01909	1.94e-118	340.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli	91061|Bacilli	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
IGHDCBEA_00961	264199.stu0269	1.67e-141	400.0	COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli	91061|Bacilli	I	Membrane-associated phospholipid phosphatase	yodM	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
IGHDCBEA_00962	264199.stu0270	4.1e-197	548.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K20342,ko:K20480	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3
IGHDCBEA_00963	1046629.Ssal_01906	0.0	1303.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli	91061|Bacilli	V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	comA	-	-	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
IGHDCBEA_00964	1046629.Ssal_01905	2.58e-71	214.0	COG3152@1|root,COG3152@2|Bacteria	2|Bacteria	L	Membrane	yhaI	-	-	-	-	-	-	-	-	-	-	-	DUF805
IGHDCBEA_00965	1046629.Ssal_01904	1.07e-47	166.0	2E26M@1|root,32XD2@2|Bacteria,1VCM1@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
IGHDCBEA_00966	1046629.Ssal_01903	8.82e-124	352.0	2DC0F@1|root,2ZC7C@2|Bacteria,1UPV2@1239|Firmicutes,4IVBC@91061|Bacilli	91061|Bacilli	S	AmiS/UreI family transporter	ureI	-	-	ko:K03191	ko05120,map05120	-	-	-	ko00000,ko00001,ko02000	1.A.29.1.3,1.A.29.1.4,1.A.29.1.5	-	-	AmiS_UreI
IGHDCBEA_00967	264199.stu0281	1.02e-61	189.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,4HIJS@91061|Bacilli	91061|Bacilli	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11965,iYO844.BSU36660	Urease_gamma
IGHDCBEA_00968	1046629.Ssal_01901	3.78e-72	216.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,4HM0I@91061|Bacilli	91061|Bacilli	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
IGHDCBEA_00969	904306.HMPREF9192_0116	0.0	1155.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,4HBTS@91061|Bacilli	91061|Bacilli	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
IGHDCBEA_00970	1046629.Ssal_01898	1.58e-100	291.0	COG2371@1|root,COG2371@2|Bacteria	2|Bacteria	O	enzyme active site formation	ureE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
IGHDCBEA_00971	1046629.Ssal_01897	1.5e-168	471.0	COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,4HHW3@91061|Bacilli	91061|Bacilli	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
IGHDCBEA_00972	1046629.Ssal_01896	3.87e-141	399.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,4HC5C@91061|Bacilli	91061|Bacilli	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
IGHDCBEA_00973	435842.HMPREF0848_01602	3.46e-204	564.0	COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,4HCED@91061|Bacilli	91061|Bacilli	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
IGHDCBEA_00974	904306.HMPREF9192_0111	1.43e-226	625.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,4HN6C@91061|Bacilli	91061|Bacilli	P	biosynthesis protein CbiM	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
IGHDCBEA_00975	1046629.Ssal_01892	1.13e-174	488.0	COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes	1239|Firmicutes	P	cobalt transport protein	nikQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
IGHDCBEA_00976	1046629.Ssal_01891	5.43e-167	467.0	COG1122@1|root,COG1122@2|Bacteria,1V16T@1239|Firmicutes,4HI15@91061|Bacilli	91061|Bacilli	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
IGHDCBEA_00977	1046629.Ssal_01890	9.97e-185	515.0	COG0834@1|root,COG0834@2|Bacteria,1VWFY@1239|Firmicutes,4HW2H@91061|Bacilli	91061|Bacilli	ET	ABC transporter substrate-binding protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IGHDCBEA_00978	1046629.Ssal_01889	4.21e-211	583.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli	91061|Bacilli	M	Belongs to the NlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
IGHDCBEA_00979	1046629.Ssal_01888	0.0	906.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli	91061|Bacilli	E	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
IGHDCBEA_00980	1046629.Ssal_01887	7.24e-242	666.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli	91061|Bacilli	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
IGHDCBEA_00981	1046629.Ssal_01886	1.27e-152	430.0	COG2011@1|root,COG2011@2|Bacteria,1V0GE@1239|Firmicutes,4HFMB@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
IGHDCBEA_00982	1046629.Ssal_01885	2.08e-267	734.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli	91061|Bacilli	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
IGHDCBEA_00983	1046629.Ssal_01880	1.98e-157	441.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli	91061|Bacilli	P	COG0569 K transport systems, NAD-binding component	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
IGHDCBEA_00984	1046629.Ssal_01879	2.11e-302	827.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli	91061|Bacilli	P	COG0168 Trk-type K transport systems, membrane components	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
IGHDCBEA_00985	1046629.Ssal_01878	3.54e-167	467.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli	91061|Bacilli	J	Ribosomal RNA small subunit methyltransferase G	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
IGHDCBEA_00986	1046629.Ssal_01877	1.33e-117	337.0	COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli	91061|Bacilli	K	metal-binding, possibly nucleic acid-binding protein	ylbN	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
IGHDCBEA_00987	1046629.Ssal_01876	2.3e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli	91061|Bacilli	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	csrR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IGHDCBEA_00988	1046629.Ssal_01875	0.0	968.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,4HWKS@91061|Bacilli	91061|Bacilli	T	Histidine kinase	covS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IGHDCBEA_00989	1046629.Ssal_01874	1.01e-105	305.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli	91061|Bacilli	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
IGHDCBEA_00990	1046629.Ssal_01873	3.02e-275	753.0	COG3611@1|root,COG3611@2|Bacteria	2|Bacteria	L	Replication initiation and membrane attachment	dnaB	-	-	ko:K03346	-	-	-	-	ko00000,ko03032	-	-	-	DnaB_2
IGHDCBEA_00991	1046629.Ssal_01872	6.23e-213	588.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli	91061|Bacilli	L	Primosomal protein DnaI	dnaI	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K11144	-	-	-	-	ko00000,ko03032	-	-	-	DnaI_N,IstB_IS21
IGHDCBEA_00992	1046629.Ssal_01871	5.05e-315	858.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
IGHDCBEA_00993	1046629.Ssal_01870	2.28e-131	374.0	2CH4S@1|root,32S58@2|Bacteria,1VC9V@1239|Firmicutes,4HNHW@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_00994	435842.HMPREF0848_01627	2.4e-296	810.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
IGHDCBEA_00995	904306.HMPREF9192_0083	7.55e-82	242.0	COG4687@1|root,COG4687@2|Bacteria,1VF36@1239|Firmicutes,4HPYI@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	manO	-	-	-	-	-	-	-	-	-	-	-	DUF956
IGHDCBEA_00996	1046629.Ssal_01867	1.22e-216	598.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli	91061|Bacilli	G	PTS system mannose fructose sorbose family IID component	manN	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
IGHDCBEA_00997	1046629.Ssal_01866	5.59e-165	464.0	COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli	91061|Bacilli	G	pts system	manM	-	-	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	M00276,M00277	R02630,R08366	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1,4.A.6.1.4	-	-	EII-Sor
IGHDCBEA_00998	1046629.Ssal_01865	1.39e-231	638.0	COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli	91061|Bacilli	G	pts system	manL	-	2.7.1.191,2.7.1.202	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	M00273,M00276	R02630,R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,4.A.6.1	-	-	EIIA-man,PTSIIB_sorb
IGHDCBEA_00999	1046629.Ssal_01864	1.62e-87	257.0	COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes	1239|Firmicutes	S	Protein conserved in bacteria	manO	-	-	-	-	-	-	-	-	-	-	-	DUF956
IGHDCBEA_01000	1046629.Ssal_01863	1.69e-203	565.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli	91061|Bacilli	G	PTS system mannose fructose sorbose family IID component	manN	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
IGHDCBEA_01001	1046629.Ssal_01862	6.45e-173	484.0	COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli	91061|Bacilli	G	pts system	manM	-	-	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	M00276,M00277	R02630,R08366	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1,4.A.6.1.4	-	-	EII-Sor
IGHDCBEA_01002	1046629.Ssal_01861	7.02e-223	616.0	COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli	91061|Bacilli	G	pts system	manX	-	2.7.1.191,2.7.1.202	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	M00273,M00276	R02630,R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,4.A.6.1	-	-	EIIA-man,PTSIIB_sorb
IGHDCBEA_01003	264199.stu0334	1.19e-177	494.0	COG1878@1|root,COG1878@2|Bacteria,1TRBQ@1239|Firmicutes,4HCAB@91061|Bacilli	91061|Bacilli	S	Metal-dependent hydrolase	XK27_00940	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
IGHDCBEA_01004	1046629.Ssal_01859	7.22e-197	545.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli	91061|Bacilli	S	hydrolases of the HAD superfamily	yitU	-	3.1.3.104	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase_3
IGHDCBEA_01005	1046629.Ssal_01858	7.03e-316	863.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli	91061|Bacilli	S	permease	XK27_07275	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
IGHDCBEA_01006	1046629.Ssal_01857	3.62e-100	290.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli	91061|Bacilli	M	ATPase or kinase	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
IGHDCBEA_01007	1046629.Ssal_01856	2.15e-116	333.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	XK27_05885	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
IGHDCBEA_01008	1046629.Ssal_01855	7.62e-273	749.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli	91061|Bacilli	K	Transcriptional	brpA	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IGHDCBEA_01009	1046629.Ssal_01854	1.75e-105	305.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli	91061|Bacilli	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
IGHDCBEA_01010	1046629.Ssal_01853	1.37e-258	712.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli	91061|Bacilli	K	Participates in both transcription termination and antitermination	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
IGHDCBEA_01011	904306.HMPREF9192_0067	9.2e-64	194.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli	91061|Bacilli	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
IGHDCBEA_01012	1046629.Ssal_01850	1.66e-56	176.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes	1239|Firmicutes	J	ribosomal protein	ylxQ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
IGHDCBEA_01013	1046629.Ssal_01848	0.0	1377.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
IGHDCBEA_01014	1046629.Ssal_01846	5.68e-76	227.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
IGHDCBEA_01015	1046629.Ssal_01845	4.79e-129	367.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HGSU@91061|Bacilli	91061|Bacilli	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
IGHDCBEA_01016	1046629.Ssal_01844	0.0	943.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli	91061|Bacilli	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13,6.3.2.7	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	-	R02786,R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
IGHDCBEA_01017	1046629.Ssal_01843	0.0	976.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli	91061|Bacilli	S	Membrane protein involved in the export of O-antigen and teichoic acid	ytgP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
IGHDCBEA_01018	1046629.Ssal_01842	0.0	1729.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli	91061|Bacilli	P	cation transport ATPase	pacL	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
IGHDCBEA_01019	1046629.Ssal_01840	1.39e-255	701.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli	91061|Bacilli	E	cystathionine	metB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
IGHDCBEA_01020	1046629.Ssal_01839	1.07e-282	772.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli	91061|Bacilli	E	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	malY	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IGHDCBEA_01021	1046629.Ssal_01838	0.0	1085.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26,3.2.1.65	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311	RC00028,RC00077,RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N,Glyco_hydro_43
IGHDCBEA_01022	1046629.Ssal_01837	0.0	1635.0	COG1621@1|root,COG1621@2|Bacteria,1TR8C@1239|Firmicutes,4HBYU@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 68 family	sacB	GO:0005575,GO:0005576	2.4.1.10,2.4.1.9	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R04194,R05140	RC00077,RC00247	ko00000,ko00001,ko01000,ko01003	-	GH68	-	Glyco_hydro_68,Gram_pos_anchor,SH3_8
IGHDCBEA_01023	1046629.Ssal_01836	1.06e-145	410.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli	91061|Bacilli	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
IGHDCBEA_01024	1046629.Ssal_01835	1.86e-135	384.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli	91061|Bacilli	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
IGHDCBEA_01025	1046629.Ssal_01834	5.21e-94	275.0	COG3679@1|root,COG3679@2|Bacteria,1V3R6@1239|Firmicutes,4HGYS@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0342 family	ylbF	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
IGHDCBEA_01026	1046629.Ssal_01833	6.15e-62	189.0	COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli	91061|Bacilli	S	UPF0298 protein	ylbG	-	-	-	-	-	-	-	-	-	-	-	DUF2129
IGHDCBEA_01027	1046629.Ssal_01208	1.05e-169	474.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli	91061|Bacilli	C	nitroreductase	nfrA	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
IGHDCBEA_01028	1046629.Ssal_01207	4.14e-202	559.0	COG1409@1|root,COG1409@2|Bacteria,1V9B5@1239|Firmicutes,4HJX0@91061|Bacilli	91061|Bacilli	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
IGHDCBEA_01029	1046629.Ssal_01206	5.78e-268	733.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli	91061|Bacilli	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
IGHDCBEA_01030	1046629.Ssal_01205	1.08e-231	638.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
IGHDCBEA_01031	1046629.Ssal_01204	8.67e-160	448.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli	91061|Bacilli	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
IGHDCBEA_01032	904306.HMPREF9192_1646	1.2e-210	583.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli	91061|Bacilli	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
IGHDCBEA_01033	1046629.Ssal_01202	1.68e-118	338.0	COG1051@1|root,COG1051@2|Bacteria,1V66I@1239|Firmicutes,4HHRE@91061|Bacilli	91061|Bacilli	F	NTP pyrophosphohydrolases including oxidative damage repair enzymes	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IGHDCBEA_01034	1046629.Ssal_01201	3.84e-235	652.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli	91061|Bacilli	S	permease	XK27_05220	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
IGHDCBEA_01035	1046629.Ssal_01200	1.07e-284	779.0	COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli	91061|Bacilli	G	COG0457 FOG TPR repeat	XK27_05225	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
IGHDCBEA_01036	1046629.Ssal_01199	3.24e-126	359.0	COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli	91061|Bacilli	U	Belongs to the peptidase S26 family	sipC	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
IGHDCBEA_01037	1046629.Ssal_01197	0.0	1064.0	COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	lytC_1	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3,SLH
IGHDCBEA_01038	1046629.Ssal_01197	2.5e-83	265.0	COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	lytC_1	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3,SLH
IGHDCBEA_01039	1046629.Ssal_01196	8.35e-297	809.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli	91061|Bacilli	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
IGHDCBEA_01040	904306.HMPREF9192_1653	4.23e-115	330.0	2FI04@1|root,349T2@2|Bacteria,1VQ5S@1239|Firmicutes,4HYC5@91061|Bacilli	91061|Bacilli	S	Family of unknown function (DUF5322)	ebsA	-	-	-	-	-	-	-	-	-	-	-	DUF5322
IGHDCBEA_01041	904306.HMPREF9192_1655	6.59e-27	109.0	COG1388@1|root,COG1388@2|Bacteria,1VD79@1239|Firmicutes,4HT02@91061|Bacilli	91061|Bacilli	M	LysM domain	XK27_09115	-	-	-	-	-	-	-	-	-	-	-	LysM
IGHDCBEA_01042	1046629.Ssal_01193	3.39e-155	436.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli	91061|Bacilli	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
IGHDCBEA_01043	1046629.Ssal_01192	1.1e-115	332.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HI4P@91061|Bacilli	91061|Bacilli	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
IGHDCBEA_01044	1046629.Ssal_01191	2.36e-38	128.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
IGHDCBEA_01045	1046629.Ssal_01190	1.82e-73	221.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
IGHDCBEA_01046	1046629.Ssal_01189	5.14e-108	311.0	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,4HKYX@91061|Bacilli	91061|Bacilli	K	Gnat family	XK27_03610	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
IGHDCBEA_01047	1046629.Ssal_01188	6.67e-120	342.0	2BWFV@1|root,32QWV@2|Bacteria,1V8UN@1239|Firmicutes,4HK47@91061|Bacilli	91061|Bacilli	-	-	yybC	-	-	-	-	-	-	-	-	-	-	-	DUF2798
IGHDCBEA_01048	1046629.Ssal_01187	1.38e-37	125.0	COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli	91061|Bacilli	G	Belongs to the 4-oxalocrotonate tautomerase family	dmpI	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
IGHDCBEA_01049	1046629.Ssal_01186	0.0	935.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli	91061|Bacilli	E	Dipeptidase	pepV	-	3.5.1.18	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	M00016	R00899,R02734,R04951	RC00064,RC00090,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
IGHDCBEA_01050	1046629.Ssal_01185	2.28e-144	406.0	COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli	91061|Bacilli	L	Uracil-DNA glycosylase	ung2	-	-	-	-	-	-	-	-	-	-	-	UDG
IGHDCBEA_01052	1046629.Ssal_00677	0.0	1608.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli	91061|Bacilli	L	ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
IGHDCBEA_01053	264199.stu1395	6.56e-277	759.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli	91061|Bacilli	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
IGHDCBEA_01054	1046629.Ssal_00675	0.0	1783.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,Laminin_G_3,YSIRK_signal
IGHDCBEA_01055	1046629.Ssal_00673	0.0	3332.0	COG3064@1|root,COG3583@1|root,COG3064@2|Bacteria,COG3583@2|Bacteria,1TRAR@1239|Firmicutes,4HEH7@91061|Bacilli	91061|Bacilli	M	signal peptide protein, YSIRK family	-	-	-	ko:K08643	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FIVAR,G5,Gram_pos_anchor,Peptidase_M26_C,Peptidase_M26_N,Trypsin_2,YSIRK_signal
IGHDCBEA_01056	1046629.Ssal_00672	0.0	3177.0	COG4932@1|root,COG4932@2|Bacteria,1UXB4@1239|Firmicutes,4HCTD@91061|Bacilli	91061|Bacilli	M	Pilin isopeptide linkage domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cna_B,Collagen_bind,FctA,Gram_pos_anchor,YSIRK_signal
IGHDCBEA_01058	1046629.Ssal_01437	1.75e-228	628.0	COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli	91061|Bacilli	O	Peptidase U32	yrrN	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
IGHDCBEA_01059	904306.HMPREF9192_1140	0.0	874.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli	91061|Bacilli	O	Peptidase U32	yrrO	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
IGHDCBEA_01060	435842.HMPREF0848_00340	2.44e-69	209.0	COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,4HMGX@91061|Bacilli	91061|Bacilli	S	CHY zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHY
IGHDCBEA_01061	1046629.Ssal_01434	1.8e-111	322.0	COG1268@1|root,COG1268@2|Bacteria,1VA1G@1239|Firmicutes,4HNE8@91061|Bacilli	91061|Bacilli	S	biotin synthase	bioY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
IGHDCBEA_01063	264199.stu0676	2.97e-45	145.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	XK27_12190	-	-	-	-	-	-	-	-	-	-	-	PC4
IGHDCBEA_01064	1046629.Ssal_01431	4.64e-295	808.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli	91061|Bacilli	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
IGHDCBEA_01066	904306.HMPREF9192_1147	0.0	986.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
IGHDCBEA_01067	1046629.Ssal_01428	1.82e-214	602.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Transglycosylas
IGHDCBEA_01068	904293.HMPREF9176_0571	1.22e-36	130.0	2BXK6@1|root,33WGZ@2|Bacteria,1VVCA@1239|Firmicutes,4HWEI@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01069	1046629.Ssal_01424	1.88e-223	615.0	COG1011@1|root,COG1011@2|Bacteria,1V5P7@1239|Firmicutes,4HHGY@91061|Bacilli	91061|Bacilli	S	hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
IGHDCBEA_01070	1046629.Ssal_01423	2.41e-148	417.0	COG0406@1|root,COG0406@2|Bacteria,1V7EZ@1239|Firmicutes,4HJCK@91061|Bacilli	91061|Bacilli	G	Phosphoglycerate mutase	pgm	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IGHDCBEA_01071	1046629.Ssal_01422	1.23e-105	305.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HIH1@91061|Bacilli	91061|Bacilli	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
IGHDCBEA_01072	1046629.Ssal_01421	1.51e-193	539.0	COG3757@1|root,COG3757@2|Bacteria,1V2YH@1239|Firmicutes,4HI8U@91061|Bacilli	91061|Bacilli	M	Glycosyl hydrolase, family 25	-	-	3.5.1.28	ko:K01447,ko:K07273	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Glyco_hydro_25
IGHDCBEA_01074	1046629.Ssal_01419	6.65e-198	548.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,4HDIH@91061|Bacilli	91061|Bacilli	G	hydrolase	hmpP2	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IGHDCBEA_01075	1046629.Ssal_01418	2.42e-146	412.0	COG2141@1|root,COG2141@2|Bacteria,1VJRB@1239|Firmicutes,4ISN7@91061|Bacilli	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01076	1046629.Ssal_01417	1.22e-269	739.0	COG1073@1|root,COG1073@2|Bacteria,1VEWD@1239|Firmicutes,4IQU0@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF2974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
IGHDCBEA_01077	322159.STER_1071	8.45e-305	836.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HDRS@91061|Bacilli	91061|Bacilli	K	Cell envelope-like function transcriptional attenuator common domain protein	cps4A	-	-	-	-	-	-	-	-	-	-	-	DNA_PPF,LytR_cpsA_psr
IGHDCBEA_01078	1046629.Ssal_01181	1.28e-172	481.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli	91061|Bacilli	GM	Capsular polysaccharide biosynthesis protein	cpsB	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
IGHDCBEA_01079	1046629.Ssal_01180	2.45e-150	424.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli	91061|Bacilli	M	biosynthesis protein	capA	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
IGHDCBEA_01080	1046629.Ssal_01179	1.34e-156	441.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli	91061|Bacilli	D	COG0489 ATPases involved in chromosome partitioning	cpsD	-	-	-	-	-	-	-	-	-	-	-	AAA_31
IGHDCBEA_01081	1046629.Ssal_01178	0.0	891.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB3Z@91061|Bacilli	91061|Bacilli	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	cpsE	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
IGHDCBEA_01082	999425.HMPREF9186_01146	3.64e-271	743.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,4IPU2@91061|Bacilli	91061|Bacilli	M	group 1 family protein	rgpAc	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	DUF1972,Glycos_transf_1
IGHDCBEA_01083	176090.SSIN_1891	1.76e-202	561.0	COG3475@1|root,COG3475@2|Bacteria,1V48Q@1239|Firmicutes	1239|Firmicutes	M	LPS biosynthesis protein	licD1	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
IGHDCBEA_01084	176090.SSIN_1890	2.52e-152	430.0	COG1211@1|root,COG1211@2|Bacteria,1TS1B@1239|Firmicutes,4HHZZ@91061|Bacilli	91061|Bacilli	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
IGHDCBEA_01085	176090.SSIN_1889	4.78e-188	530.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,4HC1B@91061|Bacilli	91061|Bacilli	GM	Dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
IGHDCBEA_01086	176090.SSIN_1888	2.07e-171	486.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IGHDCBEA_01087	904294.HMPREF9182_1125	1.36e-101	307.0	COG3774@1|root,COG3774@2|Bacteria,1TPTB@1239|Firmicutes	1239|Firmicutes	M	Capsular polysaccharide synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caps_synth
IGHDCBEA_01088	693979.Bache_2163	1.43e-37	140.0	COG1215@1|root,COG1215@2|Bacteria,4PNTB@976|Bacteroidetes,2G0XV@200643|Bacteroidia,4AVER@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IGHDCBEA_01089	373153.SPD_0323	1.47e-48	177.0	2C0FW@1|root,3048C@2|Bacteria,1TW9F@1239|Firmicutes,4I50U@91061|Bacilli,1WVP6@1313|Streptococcus pneumoniae	91061|Bacilli	S	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01090	1095738.HMPREF1047_0074	1.09e-119	357.0	COG0438@1|root,COG0438@2|Bacteria,1V4TS@1239|Firmicutes,4HC19@91061|Bacilli	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
IGHDCBEA_01091	888833.HMPREF9421_0507	4.12e-298	818.0	COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HC84@91061|Bacilli	91061|Bacilli	S	Polysaccharide biosynthesis protein	wzx	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
IGHDCBEA_01092	1035189.HMPREF9954_0534	1.54e-273	747.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,43FP1@68892|Streptococcus infantis	91061|Bacilli	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
IGHDCBEA_01093	888048.HMPREF8577_1409	3.03e-220	611.0	COG0438@1|root,COG0438@2|Bacteria,1UZFG@1239|Firmicutes,4ISTK@91061|Bacilli	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01094	1046629.Ssal_00081	2.95e-239	657.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
IGHDCBEA_01095	1046629.Ssal_00083	4.29e-64	196.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli	91061|Bacilli	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
IGHDCBEA_01096	1046629.Ssal_00084	3.17e-142	402.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
IGHDCBEA_01097	1046629.Ssal_00085	2.13e-135	384.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
IGHDCBEA_01098	264199.stu1932	6e-60	185.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli	91061|Bacilli	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
IGHDCBEA_01099	1046629.Ssal_00087	5.06e-196	543.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli	91061|Bacilli	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
IGHDCBEA_01100	1000570.HMPREF9966_1567	8.13e-62	189.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,42DQ5@671232|Streptococcus anginosus group	91061|Bacilli	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
IGHDCBEA_01101	1046629.Ssal_00089	1.21e-71	216.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli	91061|Bacilli	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
IGHDCBEA_01102	1046629.Ssal_00090	9.44e-153	429.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli	91061|Bacilli	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
IGHDCBEA_01103	1046629.Ssal_00091	4.35e-94	274.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli	91061|Bacilli	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
IGHDCBEA_01104	1046629.Ssal_00092	6.2e-35	119.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
IGHDCBEA_01105	1046629.Ssal_00093	3.08e-52	164.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
IGHDCBEA_01106	1046629.Ssal_00094	2.55e-79	236.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli	91061|Bacilli	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
IGHDCBEA_01107	1046629.Ssal_00095	5.67e-64	195.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
IGHDCBEA_01108	1046629.Ssal_00096	5.86e-122	348.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli	91061|Bacilli	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
IGHDCBEA_01109	1000570.HMPREF9966_1576	2.03e-39	130.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,42EG0@671232|Streptococcus anginosus group	91061|Bacilli	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
IGHDCBEA_01110	1046629.Ssal_00098	3.78e-88	259.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
IGHDCBEA_01111	1046629.Ssal_00099	5.88e-121	345.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
IGHDCBEA_01112	1046629.Ssal_00100	7.15e-75	224.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
IGHDCBEA_01113	1046629.Ssal_00101	7e-104	301.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli	91061|Bacilli	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
IGHDCBEA_01114	1046629.Ssal_00102	9.89e-33	113.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli	91061|Bacilli	J	ribosomal protein l30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
IGHDCBEA_01115	1046629.Ssal_00103	8.47e-85	251.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
IGHDCBEA_01116	1046629.Ssal_00104	1.37e-289	793.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli	91061|Bacilli	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
IGHDCBEA_01117	264199.stu1913	1.39e-150	424.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
IGHDCBEA_01118	1046629.Ssal_00106	6.91e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
IGHDCBEA_01119	1123301.KB904201_gene1724	3.26e-22	85.5	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
IGHDCBEA_01120	1046629.Ssal_00108	4.42e-75	225.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli	91061|Bacilli	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
IGHDCBEA_01121	1046629.Ssal_00109	1.63e-82	244.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli	91061|Bacilli	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
IGHDCBEA_01122	1046629.Ssal_00110	2.19e-219	605.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli	91061|Bacilli	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
IGHDCBEA_01123	1046629.Ssal_00111	3.03e-83	246.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli	91061|Bacilli	J	ribosomal protein l17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
IGHDCBEA_01124	435842.HMPREF0848_01943	0.0	1102.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
IGHDCBEA_01125	1046629.Ssal_02122	5.43e-90	264.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli	91061|Bacilli	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
IGHDCBEA_01126	1046629.Ssal_02121	6.33e-74	222.0	COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0342 family	ymcA	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	Com_YlbF
IGHDCBEA_01127	1046629.Ssal_02120	0.0	1622.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli	91061|Bacilli	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
IGHDCBEA_01128	1046629.Ssal_02119	1.78e-102	296.0	2E0UI@1|root,32WBZ@2|Bacteria,1VHBQ@1239|Firmicutes,4HRYH@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
IGHDCBEA_01129	904306.HMPREF9192_0027	1.54e-91	268.0	COG3279@1|root,COG3279@2|Bacteria,1VE2H@1239|Firmicutes,4IPMG@91061|Bacilli	91061|Bacilli	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
IGHDCBEA_01131	1046629.Ssal_02116	0.0	1244.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli	91061|Bacilli	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
IGHDCBEA_01133	1046629.Ssal_02114	2.17e-134	381.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
IGHDCBEA_01134	1046629.Ssal_02113	1.62e-139	393.0	COG2818@1|root,COG2818@2|Bacteria,1V9B8@1239|Firmicutes,4HJ4I@91061|Bacilli	91061|Bacilli	L	3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
IGHDCBEA_01135	1046629.Ssal_02112	8.37e-296	808.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli	91061|Bacilli	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
IGHDCBEA_01136	1046629.Ssal_02111	1.77e-261	717.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli	91061|Bacilli	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
IGHDCBEA_01137	1046629.Ssal_00669	0.0	2451.0	COG0508@1|root,COG2304@1|root,COG3468@1|root,COG4932@1|root,COG0508@2|Bacteria,COG2304@2|Bacteria,COG3468@2|Bacteria,COG4932@2|Bacteria,1UXB4@1239|Firmicutes,4HCTD@91061|Bacilli	91061|Bacilli	M	Pilin isopeptide linkage domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cna_B,Collagen_bind,FctA,Gram_pos_anchor,YSIRK_signal
IGHDCBEA_01139	904306.HMPREF9192_1631	1.44e-165	463.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli	91061|Bacilli	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IGHDCBEA_01140	1046629.Ssal_01220	5.5e-315	858.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli	91061|Bacilli	T	Histidine kinase	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
IGHDCBEA_01141	1046629.Ssal_01219	2.07e-196	544.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli	91061|Bacilli	S	Metal-dependent hydrolases of the beta-lactamase superfamily I	vicX	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
IGHDCBEA_01142	435842.HMPREF0848_00563	3.68e-53	169.0	COG2832@1|root,COG2832@2|Bacteria,1VC3R@1239|Firmicutes,4HMWE@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
IGHDCBEA_01143	1046629.Ssal_01216	5.85e-275	754.0	COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,4HGRE@91061|Bacilli	91061|Bacilli	V	protein involved in methicillin resistance	murM	-	2.3.2.10	ko:K05363	ko00550,ko01100,map00550,map01100	-	R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
IGHDCBEA_01144	1046629.Ssal_01215	3.03e-188	523.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli	91061|Bacilli	S	hydrolases of the HAD superfamily	XK27_00835	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IGHDCBEA_01145	1046629.Ssal_01213	1.2e-204	566.0	COG0454@1|root,COG0456@2|Bacteria,1VD7Z@1239|Firmicutes,4HGYD@91061|Bacilli	91061|Bacilli	K	Acetyltransferase GNAT family	XK27_00115	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IGHDCBEA_01146	1046629.Ssal_01212	2.22e-183	509.0	COG2820@1|root,COG2820@2|Bacteria,1U92J@1239|Firmicutes,4HX7F@91061|Bacilli	91061|Bacilli	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
IGHDCBEA_01147	1046629.Ssal_01211	2.05e-90	264.0	COG4506@1|root,COG4506@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1934)	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
IGHDCBEA_01148	1046629.Ssal_01209	0.0	1623.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli	91061|Bacilli	P	cation transport ATPase	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
IGHDCBEA_01149	435842.HMPREF0848_00548	2.57e-272	745.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli	91061|Bacilli	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iSB619.SA_RS11005	Epimerase_2
IGHDCBEA_01150	1046629.Ssal_01234	2.99e-176	492.0	2DSSB@1|root,33H90@2|Bacteria,1W0IB@1239|Firmicutes,4HYWM@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01152	1046629.Ssal_01232	0.0	865.0	COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,4HAAK@91061|Bacilli	91061|Bacilli	M	Glycosyltransferases, probably involved in cell wall biogenesis	ydaM	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
IGHDCBEA_01153	1046629.Ssal_01231	3.91e-268	733.0	COG3405@1|root,COG3405@2|Bacteria,1VCBY@1239|Firmicutes,4IPTW@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_8
IGHDCBEA_01155	1046629.Ssal_01229	2.5e-297	812.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli	91061|Bacilli	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
IGHDCBEA_01156	1046629.Ssal_01228	1.43e-35	120.0	2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4HRG1@91061|Bacilli	91061|Bacilli	S	DNA-directed RNA polymerase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	EpuA
IGHDCBEA_01157	904306.HMPREF9192_1622	2.58e-197	548.0	COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli	91061|Bacilli	F	DNA RNA non-specific endonuclease	endA	-	-	ko:K15051	-	-	-	-	ko00000	-	-	-	Endonuclea_NS_2,Endonuclease_NS
IGHDCBEA_01158	1046629.Ssal_01821	4.11e-123	351.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli	91061|Bacilli	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
IGHDCBEA_01159	904306.HMPREF9192_0040	1.91e-110	322.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	comFC	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
IGHDCBEA_01160	1046629.Ssal_01823	0.0	864.0	COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli	91061|Bacilli	L	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)	comFA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K02240	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1	-	-	DEAD,Helicase_C,ResIII
IGHDCBEA_01161	1046629.Ssal_01824	9.09e-142	400.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli	91061|Bacilli	S	YigZ family	yvyE	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF1949,UPF0029
IGHDCBEA_01162	1046629.Ssal_01825	1.41e-213	590.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
IGHDCBEA_01163	1046629.Ssal_01826	2.67e-144	408.0	COG0517@1|root,COG0517@2|Bacteria,1V4CD@1239|Firmicutes,4HGX4@91061|Bacilli	91061|Bacilli	S	CBS domain	XK27_04065	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
IGHDCBEA_01164	1046629.Ssal_01828	1.87e-157	442.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
IGHDCBEA_01165	1046629.Ssal_01829	5.4e-175	488.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli	91061|Bacilli	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
IGHDCBEA_01166	1046629.Ssal_01830	1.64e-184	518.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HDIU@91061|Bacilli	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
IGHDCBEA_01167	1046629.Ssal_01831	1.65e-189	528.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
IGHDCBEA_01168	1046629.Ssal_01832	1.77e-270	742.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli	91061|Bacilli	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
IGHDCBEA_01169	1046629.Ssal_00944	4.36e-40	133.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli	91061|Bacilli	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
IGHDCBEA_01170	1046629.Ssal_00945	9.34e-221	608.0	COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli	91061|Bacilli	F	Pantothenic acid kinase	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
IGHDCBEA_01171	1046629.Ssal_00946	5.33e-135	382.0	COG2813@1|root,COG2813@2|Bacteria,1V3JX@1239|Firmicutes,4IR00@91061|Bacilli	91061|Bacilli	J	Methyltransferase small domain protein	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
IGHDCBEA_01172	1046629.Ssal_00947	5.64e-296	809.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
IGHDCBEA_01173	1046629.Ssal_00948	2.88e-144	408.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835	DeoC
IGHDCBEA_01174	1046629.Ssal_00949	8.58e-85	250.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli	91061|Bacilli	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
IGHDCBEA_01175	1046629.Ssal_00950	4.93e-245	674.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HF7R@91061|Bacilli	91061|Bacilli	S	membrane	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
IGHDCBEA_01176	435842.HMPREF0848_00802	0.0	969.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli	91061|Bacilli	S	ABC transporter, ATP-binding protein	mglA	-	3.6.3.17	ko:K02056,ko:K06400	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
IGHDCBEA_01177	1046629.Ssal_00952	7.41e-235	648.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli	91061|Bacilli	S	Belongs to the binding-protein-dependent transport system permease family	mglC	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
IGHDCBEA_01178	1046629.Ssal_00953	8.2e-218	602.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli	91061|Bacilli	S	Belongs to the binding-protein-dependent transport system permease family	yufQ	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
IGHDCBEA_01179	1046629.Ssal_00954	5.09e-154	432.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	yqgX	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
IGHDCBEA_01180	1046629.Ssal_00957	0.0	1601.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
IGHDCBEA_01181	1046629.Ssal_00958	1.55e-105	305.0	COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	ypmB	-	-	-	-	-	-	-	-	-	-	-	PepSY
IGHDCBEA_01182	264199.stu0817	6.82e-273	748.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli	91061|Bacilli	E	Aminotransferase	aspB	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297	2.6.1.1,2.6.1.14	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IGHDCBEA_01183	904306.HMPREF9192_1250	0.0	907.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
IGHDCBEA_01185	999425.HMPREF9186_00395	4.22e-254	701.0	COG0477@1|root,COG2814@2|Bacteria,1V6VB@1239|Firmicutes,4IT0A@91061|Bacilli	91061|Bacilli	EGP	Major Facilitator Superfamily	pmrB	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IGHDCBEA_01186	1046629.Ssal_00962	5.28e-83	245.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli	91061|Bacilli	J	endoribonuclease L-PSP	aldR	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
IGHDCBEA_01187	1046629.Ssal_00963	1.3e-159	446.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli	91061|Bacilli	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
IGHDCBEA_01188	1046629.Ssal_00964	7.04e-107	307.0	COG0720@1|root,COG0720@2|Bacteria,1V9HU@1239|Firmicutes,4HJEX@91061|Bacilli	91061|Bacilli	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
IGHDCBEA_01189	904306.HMPREF9192_1255	3.04e-173	483.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli	91061|Bacilli	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
IGHDCBEA_01190	904306.HMPREF9192_1256	5.6e-123	349.0	COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli	91061|Bacilli	S	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
IGHDCBEA_01191	1046629.Ssal_00969	8.07e-286	804.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4297,PhageMin_Tail
IGHDCBEA_01192	1046629.Ssal_00970	3.8e-176	491.0	COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli	91061|Bacilli	S	cyclic nucleotide-binding protein	yejC	-	-	-	-	-	-	-	-	-	-	-	DUF1003
IGHDCBEA_01193	1046629.Ssal_00971	1.78e-210	582.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli	91061|Bacilli	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
IGHDCBEA_01194	1046629.Ssal_00972	1.57e-234	645.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli	91061|Bacilli	S	Required for morphogenesis under gluconeogenic growth conditions	yvcK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
IGHDCBEA_01195	1046629.Ssal_00973	6.93e-207	573.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli	91061|Bacilli	K	May be required for sporulation	whiA	GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
IGHDCBEA_01196	1046629.Ssal_00974	0.0	948.0	COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli	91061|Bacilli	E	Dipeptidase	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
IGHDCBEA_01197	1046629.Ssal_00975	3.51e-185	516.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	XK27_10720	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
IGHDCBEA_01198	1046629.Ssal_00976	0.0	1018.0	COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli	91061|Bacilli	P	Belongs to the bacterial solute-binding protein 9 family	adcA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZinT,ZnuA
IGHDCBEA_01201	1046629.Ssal_00979	3.33e-221	612.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes	1239|Firmicutes	S	Membrane	yeiH	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
IGHDCBEA_01202	1046629.Ssal_00980	3.54e-167	467.0	COG1705@1|root,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli	91061|Bacilli	NU	muramidase	-	-	-	ko:K02395,ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02035	-	CBM50	-	Glucosaminidase,LysM
IGHDCBEA_01203	435842.HMPREF0848_00777	5.13e-213	588.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,4HC5J@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	cpsY	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IGHDCBEA_01204	1046629.Ssal_00983	0.0	1160.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli	91061|Bacilli	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iSB619.SA_RS11245,iYO844.BSU01780	GATase_6,SIS
IGHDCBEA_01205	1046629.Ssal_00985	7.1e-78	231.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli	91061|Bacilli	P	Alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
IGHDCBEA_01206	1046629.Ssal_00986	3.36e-135	384.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	yecS_2	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IGHDCBEA_01207	1046629.Ssal_00987	7.5e-146	411.0	COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HE6M@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IGHDCBEA_01208	1046629.Ssal_00988	5.28e-201	556.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes	1239|Firmicutes	ET	ABC transporter substrate-binding protein	aatB	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IGHDCBEA_01209	1046629.Ssal_00989	0.0	930.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	polYB	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IGHDCBEA_01210	435842.HMPREF0848_00770	1.19e-65	201.0	2E59Z@1|root,33028@2|Bacteria,1VFMU@1239|Firmicutes,4HQG9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01211	1046629.Ssal_00990	3.57e-61	187.0	2E660@1|root,330UP@2|Bacteria,1VFJD@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01212	904306.HMPREF9192_1827	1.41e-240	661.0	COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli	91061|Bacilli	C	alcohol dehydrogenase	adhP	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
IGHDCBEA_01213	1046629.Ssal_00994	9.52e-128	364.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
IGHDCBEA_01214	1046629.Ssal_01003	0.0	1040.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli	91061|Bacilli	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
IGHDCBEA_01215	1046629.Ssal_01004	1.5e-161	452.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli	91061|Bacilli	K	transcriptional	yvoA_2	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
IGHDCBEA_01216	435842.HMPREF0848_00765	3.35e-73	219.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli	91061|Bacilli	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	ylxM	GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
IGHDCBEA_01217	1046629.Ssal_01006	0.0	952.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
IGHDCBEA_01218	435842.HMPREF0848_00763	1.33e-111	322.0	2A1RE@1|root,32VI2@2|Bacteria,1VDRR@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	ECF-ribofla_trS
IGHDCBEA_01219	1046629.Ssal_01008	1.11e-117	337.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli	91061|Bacilli	S	small molecule binding protein (contains 3H domain)	yrxA	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
IGHDCBEA_01220	1046629.Ssal_01009	2.14e-164	459.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1V758@1239|Firmicutes,4HIKZ@91061|Bacilli	91061|Bacilli	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
IGHDCBEA_01221	1046629.Ssal_01010	3.44e-202	560.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli	91061|Bacilli	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	rbgA	GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
IGHDCBEA_01222	1046629.Ssal_01011	3.64e-174	486.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
IGHDCBEA_01223	1046629.Ssal_01013	1.65e-211	585.0	COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes	1239|Firmicutes	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
IGHDCBEA_01224	1046629.Ssal_01014	1.11e-200	555.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli	91061|Bacilli	LU	DNA protecting protein DprA	dprA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
IGHDCBEA_01225	1046629.Ssal_01017	0.0	1368.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
IGHDCBEA_01226	1069533.Sinf_0951	6.29e-108	317.0	COG1131@1|root,COG1131@2|Bacteria,1VVRQ@1239|Firmicutes,4HWA2@91061|Bacilli	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
IGHDCBEA_01227	862967.SIR_0964	4.66e-69	219.0	COG4200@1|root,COG4200@2|Bacteria	2|Bacteria	V	ABC-2 family transporter protein	-	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
IGHDCBEA_01229	904306.HMPREF9192_1814	2.05e-189	526.0	2DC01@1|root,2ZC51@2|Bacteria,1V2FW@1239|Firmicutes,4HG69@91061|Bacilli	91061|Bacilli	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
IGHDCBEA_01230	904306.HMPREF9192_1813	4.67e-154	432.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,4HDA9@91061|Bacilli	91061|Bacilli	KT	Transcriptional regulatory protein, C terminal	spaR	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IGHDCBEA_01231	264199.stu0902	9.47e-294	806.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,4HEWT@91061|Bacilli	91061|Bacilli	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
IGHDCBEA_01232	1046629.Ssal_01021	0.0	892.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
IGHDCBEA_01233	1046629.Ssal_01022	2.33e-286	781.0	COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli	91061|Bacilli	E	Methionine synthase	XK27_05470	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
IGHDCBEA_01234	904306.HMPREF9192_1809	2.02e-91	268.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli	91061|Bacilli	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
IGHDCBEA_01235	1046629.Ssal_01025	0.0	1210.0	COG3266@1|root,COG3266@2|Bacteria,1VU2V@1239|Firmicutes,4HU5W@91061|Bacilli	91061|Bacilli	V	Glucan-binding protein C	-	-	-	ko:K13732	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	GbpC,Gram_pos_anchor,YSIRK_signal
IGHDCBEA_01236	1046629.Ssal_01026	5.87e-156	438.0	COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli	91061|Bacilli	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
IGHDCBEA_01237	1046629.Ssal_01027	3.66e-295	804.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli	91061|Bacilli	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
IGHDCBEA_01238	435842.HMPREF0848_00597	3.93e-116	334.0	COG3797@1|root,COG3797@2|Bacteria,1V426@1239|Firmicutes,4HI2S@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
IGHDCBEA_01239	1046629.Ssal_01029	1.51e-193	536.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
IGHDCBEA_01240	1046629.Ssal_01030	2.91e-229	636.0	COG0038@1|root,COG0038@2|Bacteria,1V07H@1239|Firmicutes,4IQYS@91061|Bacilli	91061|Bacilli	P	Chloride transporter, ClC family	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
IGHDCBEA_01241	1046629.Ssal_01031	1.24e-176	491.0	COG0518@1|root,COG0518@2|Bacteria,1V97T@1239|Firmicutes,4HIKV@91061|Bacilli	91061|Bacilli	F	glutamine amidotransferase	gat	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
IGHDCBEA_01242	1046629.Ssal_01032	3.27e-167	467.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli	91061|Bacilli	F	purine nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
IGHDCBEA_01243	904306.HMPREF9192_0472	2.48e-25	103.0	COG3464@1|root,COG3464@2|Bacteria,1VQIX@1239|Firmicutes	1239|Firmicutes	L	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IGHDCBEA_01245	1046629.Ssal_01034	0.0	1178.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
IGHDCBEA_01248	1046629.Ssal_01037	0.0	1100.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli	91061|Bacilli	EH	Belongs to the TPP enzyme family	alsS	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
IGHDCBEA_01249	1046629.Ssal_01038	1.9e-172	481.0	COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli	91061|Bacilli	H	Belongs to the alpha-acetolactate decarboxylase family	budA	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
IGHDCBEA_01250	1123298.KB904062_gene947	1.26e-53	172.0	COG5015@1|root,COG5015@2|Bacteria,1TR2Q@1239|Firmicutes,4HHXT@91061|Bacilli	91061|Bacilli	C	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
IGHDCBEA_01251	1123298.KB904062_gene948	6.03e-121	353.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,4HAQT@91061|Bacilli	91061|Bacilli	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	SIR2
IGHDCBEA_01252	658088.HMPREF0987_00818	1.03e-99	298.0	COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,24935@186801|Clostridia,27TKJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
IGHDCBEA_01253	904306.HMPREF9192_1799	1.4e-89	264.0	COG1846@1|root,COG1846@2|Bacteria,1VDJQ@1239|Firmicutes,4HN0M@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
IGHDCBEA_01254	1005705.HMPREF9967_0601	4.04e-170	478.0	COG0702@1|root,COG0702@2|Bacteria,1TWJX@1239|Firmicutes,4I5DF@91061|Bacilli,43GGB@68892|Streptococcus infantis	91061|Bacilli	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
IGHDCBEA_01255	435842.HMPREF0848_00741	3.58e-215	595.0	COG0604@1|root,COG0604@2|Bacteria,1V55H@1239|Firmicutes,4HD0S@91061|Bacilli	91061|Bacilli	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
IGHDCBEA_01256	1095726.HMPREF1116_1096	1.22e-165	464.0	COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	proV	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
IGHDCBEA_01257	888048.HMPREF8577_1786	0.0	909.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli	91061|Bacilli	P	ABC transporter	proWX	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
IGHDCBEA_01258	1114965.Spaf_0370	1.57e-139	395.0	COG2231@1|root,COG2231@2|Bacteria,1V4SG@1239|Firmicutes,4HI5U@91061|Bacilli	91061|Bacilli	L	Base excision DNA repair protein, HhH-GPD family	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
IGHDCBEA_01259	904306.HMPREF9192_1795	1.73e-177	496.0	COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,4HDAC@91061|Bacilli	91061|Bacilli	S	Phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
IGHDCBEA_01260	904306.HMPREF9192_1794	1.23e-126	362.0	COG3275@1|root,COG3275@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.7.65	ko:K16923,ko:K18967	-	M00582	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.28,9.B.34.1.1	-	-	5TM-5TMR_LYT,ECF_trnsprt,GGDEF,HATPase_c,PAS_4,PAS_7
IGHDCBEA_01261	1035189.HMPREF9954_0585	3.45e-169	474.0	COG0619@1|root,COG0619@2|Bacteria,1UYQQ@1239|Firmicutes,4HFDP@91061|Bacilli,43GHU@68892|Streptococcus infantis	91061|Bacilli	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
IGHDCBEA_01262	1046629.Ssal_01043	5.3e-203	561.0	COG1122@1|root,COG1122@2|Bacteria,1VTBJ@1239|Firmicutes,4HVE5@91061|Bacilli	91061|Bacilli	P	abc transporter atp-binding protein	-	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IGHDCBEA_01263	1046629.Ssal_01045	1.4e-192	534.0	COG1122@1|root,COG1122@2|Bacteria,1TQAV@1239|Firmicutes	1239|Firmicutes	P	'abc transporter, ATP-binding protein	-	-	-	ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IGHDCBEA_01264	28115.HR11_10180	8.4e-145	408.0	COG3316@1|root,COG3316@2|Bacteria,4NKNK@976|Bacteroidetes	976|Bacteroidetes	L	DDE domain	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
IGHDCBEA_01265	888049.HMPREF8578_1989	1.75e-10	60.8	2DJ5A@1|root,304S3@2|Bacteria,1TX35@1239|Firmicutes,4I5Z7@91061|Bacilli,1WQ6Z@1303|Streptococcus oralis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01266	888048.HMPREF8577_1220	4.48e-72	219.0	2BS9S@1|root,32XMN@2|Bacteria,1VA8B@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function with HXXEE motif	-	-	-	-	-	-	-	-	-	-	-	-	HXXEE
IGHDCBEA_01267	1046629.Ssal_01052	1.54e-136	386.0	COG1309@1|root,COG1309@2|Bacteria,1TSUJ@1239|Firmicutes,4IPZN@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
IGHDCBEA_01268	435842.HMPREF0848_00730	4.43e-196	545.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli	91061|Bacilli	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
IGHDCBEA_01269	1114965.Spaf_1748	4.07e-248	682.0	COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
IGHDCBEA_01270	1095738.HMPREF1047_0980	1.24e-237	654.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,1WQ4Q@1303|Streptococcus oralis	91061|Bacilli	E	Zinc-binding dehydrogenase	adhB	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
IGHDCBEA_01271	322159.STER_0955	4.05e-54	175.0	COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,4HUI7@91061|Bacilli	91061|Bacilli	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
IGHDCBEA_01272	1046629.Ssal_01067	1.62e-141	400.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4IPIP@91061|Bacilli	91061|Bacilli	S	HAD hydrolase, family IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
IGHDCBEA_01273	1046629.Ssal_01069	4.93e-202	568.0	COG2304@1|root,COG2304@2|Bacteria,1V09B@1239|Firmicutes,4HSNZ@91061|Bacilli	91061|Bacilli	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,VWA,YSIRK_signal
IGHDCBEA_01274	1046629.Ssal_01070	7.66e-225	620.0	COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,4HAMP@91061|Bacilli	91061|Bacilli	P	ABC-type enterochelin transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
IGHDCBEA_01275	1046629.Ssal_01071	1.18e-293	805.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli	91061|Bacilli	V	Mate efflux family protein	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
IGHDCBEA_01276	1046629.Ssal_01073	0.0	966.0	2DM53@1|root,31R8Y@2|Bacteria,1UK4X@1239|Firmicutes,4IU8I@91061|Bacilli	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01277	1046629.Ssal_01074	0.0	1063.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli	91061|Bacilli	K	RNA-binding protein homologous to eukaryotic snRNP	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
IGHDCBEA_01278	904306.HMPREF9192_1767	1.77e-170	478.0	2B4EH@1|root,31X62@2|Bacteria,1V7WE@1239|Firmicutes,4HJ8G@91061|Bacilli	91061|Bacilli	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
IGHDCBEA_01279	1046629.Ssal_01076	2.28e-120	344.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,4HM36@91061|Bacilli	91061|Bacilli	S	DJ-1 family	thiJ	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
IGHDCBEA_01280	435842.HMPREF0848_00695	2.21e-185	516.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli	91061|Bacilli	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	iYO844.BSU15530	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
IGHDCBEA_01281	435842.HMPREF0848_00694	6.84e-226	622.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli	91061|Bacilli	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
IGHDCBEA_01282	435842.HMPREF0848_00693	5.04e-164	459.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli	91061|Bacilli	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
IGHDCBEA_01283	1046629.Ssal_01081	3.05e-145	409.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli	91061|Bacilli	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15560	Pribosyltran
IGHDCBEA_01284	435842.HMPREF0848_00691	1.92e-304	835.0	COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli	91061|Bacilli	J	Belongs to the amidase family	nylA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
IGHDCBEA_01285	435842.HMPREF0848_00690	9.97e-161	454.0	COG0834@1|root,COG0834@2|Bacteria,1UHHG@1239|Firmicutes,4H9NX@91061|Bacilli	91061|Bacilli	ET	Belongs to the bacterial solute-binding protein 3 family	yckB	-	-	ko:K02030,ko:K02424	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
IGHDCBEA_01286	699248.SRA_05851	7.65e-104	305.0	COG0765@1|root,COG0765@2|Bacteria,1TQ43@1239|Firmicutes,4HCZV@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	yckA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K10009	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
IGHDCBEA_01287	1046629.Ssal_01083	0.0	1298.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	sasH	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Gram_pos_anchor,Metallophos
IGHDCBEA_01288	1046629.Ssal_01085	1.19e-216	598.0	COG2207@1|root,COG2207@2|Bacteria,1UZG6@1239|Firmicutes,4HCQS@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	bglC	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
IGHDCBEA_01289	1046629.Ssal_01086	1.19e-314	858.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
IGHDCBEA_01290	1046629.Ssal_01087	2.36e-305	834.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli	91061|Bacilli	E	(Alanine) symporter	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
IGHDCBEA_01291	1046629.Ssal_01088	0.0	1491.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
IGHDCBEA_01292	322159.STER_0995	2.71e-303	828.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli	91061|Bacilli	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IGHDCBEA_01293	1046629.Ssal_01090	4.47e-177	493.0	COG0561@1|root,COG0561@2|Bacteria,1TQTU@1239|Firmicutes,4HEHK@91061|Bacilli	91061|Bacilli	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IGHDCBEA_01294	1046629.Ssal_01091	6.77e-111	319.0	COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli	91061|Bacilli	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
IGHDCBEA_01295	1046629.Ssal_01092	1.91e-142	402.0	COG0732@1|root,COG0732@2|Bacteria,1VQES@1239|Firmicutes,4HE4K@91061|Bacilli	91061|Bacilli	V	Type I restriction modification DNA specificity domain	hsdS2	-	-	-	-	-	-	-	-	-	-	-	Methylase_S
IGHDCBEA_01296	435842.HMPREF0848_00681	1.76e-47	152.0	COG2461@1|root,COG2461@2|Bacteria	2|Bacteria	P	Hemerythrin HHE cation binding domain protein	M1-755	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
IGHDCBEA_01297	1046629.Ssal_01094	3.15e-315	859.0	COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli	91061|Bacilli	S	hemerythrin HHE cation binding domain	XK27_04775	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF438,Hemerythrin,PAS_10
IGHDCBEA_01298	1046629.Ssal_01095	4.6e-183	511.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177,ko:K03483	-	-	-	-	ko00000,ko01000,ko03000,ko03016	-	-	iSB619.SA_RS06305	TruB-C_2,TruB_C_2,TruB_N
IGHDCBEA_01299	1046629.Ssal_01096	1.42e-215	595.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli	91061|Bacilli	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06310	FAD_syn,Flavokinase
IGHDCBEA_01300	904306.HMPREF9192_1744	1.03e-92	271.0	COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli	91061|Bacilli	K	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress	spxA	-	-	ko:K16509	-	-	-	-	ko00000	-	-	-	ArsC
IGHDCBEA_01301	1046629.Ssal_01098	4.17e-60	185.0	COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0223 family	yktA	-	-	-	-	-	-	-	-	-	-	-	UPF0223
IGHDCBEA_01302	1046629.Ssal_01099	5.41e-183	509.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli	91061|Bacilli	G	Belongs to the inositol monophosphatase superfamily	suhB	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
IGHDCBEA_01303	1046629.Ssal_01100	1.91e-316	862.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli	91061|Bacilli	J	NOL1 NOP2 sun family protein	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
IGHDCBEA_01304	904306.HMPREF9192_1740	5.44e-198	550.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli	91061|Bacilli	P	phosphate	pstS	GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
IGHDCBEA_01305	904306.HMPREF9192_1739	6.58e-201	558.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli	91061|Bacilli	P	probably responsible for the translocation of the substrate across the membrane	pstC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
IGHDCBEA_01306	904306.HMPREF9192_1738	1.24e-200	556.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli	91061|Bacilli	P	phosphate transport system permease	pstA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
IGHDCBEA_01307	1046629.Ssal_01104	7.48e-193	535.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB2	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
IGHDCBEA_01308	1046629.Ssal_01105	2.13e-180	502.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB1	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
IGHDCBEA_01309	904306.HMPREF9192_1735	1.33e-148	419.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli	91061|Bacilli	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
IGHDCBEA_01310	1046629.Ssal_01107	0.0	1660.0	COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli	91061|Bacilli	E	aminopeptidase	pepN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
IGHDCBEA_01311	1046629.Ssal_01108	1.7e-244	673.0	COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli	91061|Bacilli	D	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division	xerS	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
IGHDCBEA_01312	1046629.Ssal_01112	8.8e-239	656.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli	91061|Bacilli	H	Lipoate-protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
IGHDCBEA_01314	322159.STER_0151	1.06e-244	676.0	COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes	1239|Firmicutes	L	Transposase	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IGHDCBEA_01315	1046629.Ssal_01114	0.0	1486.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli	91061|Bacilli	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
IGHDCBEA_01316	1046629.Ssal_01115	0.0	1028.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,4HCHB@91061|Bacilli	91061|Bacilli	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
IGHDCBEA_01317	1046629.Ssal_01116	9.35e-200	558.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	malR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IGHDCBEA_01318	1046629.Ssal_01117	7.11e-293	800.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4H9TU@91061|Bacilli	91061|Bacilli	G	ABC transporter	malX	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
IGHDCBEA_01319	904306.HMPREF9192_1726	0.0	866.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	malF	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
IGHDCBEA_01320	1046629.Ssal_01119	2.6e-194	539.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	malG	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
IGHDCBEA_01321	1046629.Ssal_01120	3.36e-270	739.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	msmX	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
IGHDCBEA_01322	435842.HMPREF0848_00653	5.62e-33	114.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
IGHDCBEA_01323	1046629.Ssal_01122	7.89e-154	433.0	COG0805@1|root,COG0805@2|Bacteria,1TTBA@1239|Firmicutes,4HAE9@91061|Bacilli	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
IGHDCBEA_01324	1046629.Ssal_01123	0.0	997.0	COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli	91061|Bacilli	P	COG0672 High-affinity Fe2 Pb2 permease	ywbL	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
IGHDCBEA_01325	904306.HMPREF9192_1720	1.01e-294	803.0	COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli	91061|Bacilli	P	peroxidase	ywbN	GO:0005575,GO:0005576	-	ko:K07223,ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	iYO844.BSU38260	Dyp_perox,TAT_signal
IGHDCBEA_01326	1046629.Ssal_01125	1.32e-193	538.0	COG2822@1|root,COG2822@2|Bacteria,1TS89@1239|Firmicutes,4HB0W@91061|Bacilli	91061|Bacilli	P	periplasmic lipoprotein involved in iron transport	ycdO	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511	-	ko:K07224	-	-	-	-	ko00000,ko02000	2.A.108.2.3	-	-	Peptidase_M75
IGHDCBEA_01327	1046629.Ssal_01131	0.0	2396.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli	91061|Bacilli	G	belongs to the glycosyl hydrolase 13 family	pulA2	-	3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	-	R02108,R02111,R02112,R11262	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal
IGHDCBEA_01328	1046629.Ssal_01132	1.68e-88	261.0	COG0860@1|root,COG0860@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	lytC_1	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3,SLH
IGHDCBEA_01329	1046629.Ssal_00206	9.91e-289	786.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli	91061|Bacilli	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
IGHDCBEA_01330	1046629.Ssal_00205	4.62e-20	80.5	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
IGHDCBEA_01331	1046629.Ssal_00204	1.09e-134	381.0	COG2249@1|root,COG2249@2|Bacteria,1V59U@1239|Firmicutes,4HHZC@91061|Bacilli	91061|Bacilli	S	NADPH-quinone reductase (modulator of drug activity B)	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
IGHDCBEA_01332	1046629.Ssal_00203	1.62e-136	387.0	COG1309@1|root,COG1309@2|Bacteria,1V0VT@1239|Firmicutes,4HPD3@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
IGHDCBEA_01333	1046629.Ssal_00202	1.02e-237	655.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli	91061|Bacilli	S	RNA-binding protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
IGHDCBEA_01334	1046629.Ssal_00201	1.09e-181	506.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli	91061|Bacilli	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins	yidC	GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
IGHDCBEA_01335	264199.stu1811	9.69e-72	216.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
IGHDCBEA_01336	1046629.Ssal_00199	0.0	909.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli	91061|Bacilli	E	Argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
IGHDCBEA_01337	1046629.Ssal_00198	8.63e-295	803.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli	91061|Bacilli	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
IGHDCBEA_01338	1046629.Ssal_02031	3.95e-169	473.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli	91061|Bacilli	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
IGHDCBEA_01339	1046629.Ssal_02032	7.38e-225	620.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli	91061|Bacilli	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
IGHDCBEA_01340	1046629.Ssal_02033	6.59e-108	311.0	COG0454@1|root,COG0456@2|Bacteria,1VCQJ@1239|Firmicutes,4HN13@91061|Bacilli	91061|Bacilli	K	Acetyltransferase GNAT Family	XK27_02675	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IGHDCBEA_01341	1046629.Ssal_02034	1.43e-100	291.0	COG0494@1|root,COG0494@2|Bacteria,1V8D5@1239|Firmicutes,4HJKW@91061|Bacilli	91061|Bacilli	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IGHDCBEA_01342	1046629.Ssal_02035	1.76e-109	315.0	2E0MY@1|root,32W75@2|Bacteria,1VFZQ@1239|Firmicutes,4HKWR@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3013)	XK27_03960	-	-	-	-	-	-	-	-	-	-	-	DUF3013
IGHDCBEA_01343	1046629.Ssal_02036	0.0	1060.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
IGHDCBEA_01344	1046629.Ssal_02039	1.24e-101	298.0	COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli	91061|Bacilli	K	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling	rpoE	-	-	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	-	-	-	HARE-HTH
IGHDCBEA_01345	1046629.Ssal_02041	2.12e-291	797.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
IGHDCBEA_01346	1046629.Ssal_02043	7.93e-177	494.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli	91061|Bacilli	M	mechanosensitive ion channel	ykuT	GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004	-	ko:K16052,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3,1.A.23.4	-	-	MS_channel
IGHDCBEA_01347	1046629.Ssal_02044	5.57e-115	329.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigH	-	-	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IGHDCBEA_01348	1046629.Ssal_00935	0.0	1119.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli	91061|Bacilli	G	Phosphoglucomutase	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IGHDCBEA_01349	1046629.Ssal_00936	1.72e-117	337.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
IGHDCBEA_01350	1046629.Ssal_00938	1.45e-118	340.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,4HFPD@91061|Bacilli	91061|Bacilli	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
IGHDCBEA_01351	1046629.Ssal_00939	2.12e-120	344.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
IGHDCBEA_01352	1046629.Ssal_00940	1.6e-149	422.0	COG0452@1|root,COG0452@2|Bacteria,1V7YG@1239|Firmicutes,4HMIF@91061|Bacilli	91061|Bacilli	H	Phosphopantothenate-cysteine ligase	coaB	-	6.3.2.5	ko:K21977	ko00770,map00770	M00120	R04231	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP
IGHDCBEA_01353	1046629.Ssal_00941	0.0	1088.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli	91061|Bacilli	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
IGHDCBEA_01354	1046629.Ssal_00942	2.39e-154	434.0	COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli	91061|Bacilli	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ciaR	-	-	ko:K14983	ko02020,ko02024,map02020,map02024	M00521	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IGHDCBEA_01355	904306.HMPREF9192_1234	2.37e-308	844.0	COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli	91061|Bacilli	T	Histidine kinase	ciaH	-	2.7.13.3	ko:K14982	ko02020,ko02024,map02020,map02024	M00521	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
IGHDCBEA_01358	1046629.Ssal_01720	8.24e-149	419.0	COG1131@1|root,COG1131@2|Bacteria,1VSY6@1239|Firmicutes	1239|Firmicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_01359	1046629.Ssal_01719	5.95e-153	431.0	2E0PZ@1|root,32W8Q@2|Bacteria,1VRGN@1239|Firmicutes,4HWS3@91061|Bacilli	91061|Bacilli	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
IGHDCBEA_01360	1046629.Ssal_01717	2.13e-295	808.0	COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4HKY4@91061|Bacilli	91061|Bacilli	T	GHKL domain	-	-	2.7.13.3	ko:K07706	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5
IGHDCBEA_01361	1046629.Ssal_01716	3.53e-172	481.0	COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli	91061|Bacilli	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K07707	ko02020,ko02024,map02020,map02024	M00495	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
IGHDCBEA_01364	1046629.Ssal_02148	1.36e-223	617.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli	91061|Bacilli	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
IGHDCBEA_01365	1046629.Ssal_02149	2.19e-149	441.0	COG3883@1|root,COG3942@1|root,COG3883@2|Bacteria,COG3942@2|Bacteria,1VCXB@1239|Firmicutes,4IS6H@91061|Bacilli	91061|Bacilli	S	CHAP domain	pcsB	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CHAP
IGHDCBEA_01366	1046629.Ssal_02150	2.05e-110	318.0	COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNAD@91061|Bacilli	91061|Bacilli	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
IGHDCBEA_01367	435842.HMPREF0848_01966	1.68e-157	446.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli	91061|Bacilli	M	Involved in formation and maintenance of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
IGHDCBEA_01369	1046629.Ssal_00933	0.0	1485.0	COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli	91061|Bacilli	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
IGHDCBEA_01370	1046629.Ssal_00934	8.88e-213	587.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes	1239|Firmicutes	E	reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
IGHDCBEA_01371	904306.HMPREF9192_1626	6.34e-179	498.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	glnQ	-	-	ko:K10041	ko02010,map02010	M00228	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IGHDCBEA_01372	1046629.Ssal_01223	9e-190	528.0	COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli	91061|Bacilli	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	peb1A	-	-	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	M00228,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
IGHDCBEA_01374	888048.HMPREF8577_0354	1.63e-103	301.0	COG1714@1|root,COG1714@2|Bacteria,1V7WG@1239|Firmicutes,4HK3X@91061|Bacilli	91061|Bacilli	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
IGHDCBEA_01375	1046629.Ssal_00866	2.86e-196	546.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K20342,ko:K20480	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3,TPR_8
IGHDCBEA_01376	1046629.Ssal_00865	6.38e-195	541.0	COG1131@1|root,COG1131@2|Bacteria,1TRNT@1239|Firmicutes,4HB3P@91061|Bacilli	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_01377	1046629.Ssal_00863	1.82e-131	377.0	2DN7R@1|root,32W08@2|Bacteria,1VBHE@1239|Firmicutes,4HMWG@91061|Bacilli	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
IGHDCBEA_01378	1046629.Ssal_00862	9.5e-209	578.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K20342,ko:K20480	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_19,HTH_3,TPR_8
IGHDCBEA_01379	1121865.OMW_02221	7.34e-60	199.0	2DK2Q@1|root,3089C@2|Bacteria,1U31N@1239|Firmicutes,4ICRQ@91061|Bacilli,4B5FA@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01380	768726.HMPREF9178_0412	2.14e-05	54.3	2DKFJ@1|root,309C7@2|Bacteria,1U4TF@1239|Firmicutes,4IEIT@91061|Bacilli,2TQ9W@28037|Streptococcus mitis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01382	1046629.Ssal_00857	7.22e-114	327.0	28I5N@1|root,2Z88Y@2|Bacteria,1UQGQ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
IGHDCBEA_01383	1046629.Ssal_00854	7.12e-150	422.0	28VMD@1|root,2ZHPJ@2|Bacteria,1W54J@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01384	322159.STER_1290	2.32e-131	374.0	COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli	91061|Bacilli	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	desR	-	-	ko:K02479,ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
IGHDCBEA_01385	1046629.Ssal_00851	2.3e-236	652.0	COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli	91061|Bacilli	T	Histidine kinase	desK	GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
IGHDCBEA_01386	435842.HMPREF0848_00890	1.96e-168	471.0	COG0842@1|root,COG0842@2|Bacteria,1V1AU@1239|Firmicutes	1239|Firmicutes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
IGHDCBEA_01387	322159.STER_1293	2.22e-200	556.0	COG1131@1|root,COG1131@2|Bacteria,1UZ04@1239|Firmicutes	1239|Firmicutes	V	'abc transporter, ATP-binding protein	XK27_09825	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_01390	1046629.Ssal_00845	3.06e-212	587.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli	91061|Bacilli	S	Transporter	yocS	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	iYO844.BSU19350	SBF
IGHDCBEA_01391	264199.stu1331	4.74e-106	305.0	COG0295@1|root,COG0295@2|Bacteria,1V58S@1239|Firmicutes,4HHTM@91061|Bacilli	91061|Bacilli	F	cytidine deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
IGHDCBEA_01392	1046629.Ssal_00843	5.18e-148	419.0	COG0842@1|root,COG0842@2|Bacteria,1V1AU@1239|Firmicutes,4HHQW@91061|Bacilli	91061|Bacilli	V	Transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
IGHDCBEA_01393	1046629.Ssal_00842	1.05e-196	546.0	COG1131@1|root,COG1131@2|Bacteria,1UZ04@1239|Firmicutes,4HDGQ@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	XK27_09825	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_01396	435842.HMPREF0848_00907	4.78e-120	342.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	XK27_05000	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
IGHDCBEA_01397	264199.stu1333	0.0	1152.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli	91061|Bacilli	V	ABC transporter (permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IGHDCBEA_01398	435842.HMPREF0848_00909	4.97e-170	476.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli	91061|Bacilli	V	ABC transporter, ATP-binding protein	yxdL	-	-	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	M00258,M00731,M00737	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.134	-	-	ABC_tran
IGHDCBEA_01399	264199.stu1335	2.52e-215	596.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,4HG2J@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
IGHDCBEA_01400	1046629.Ssal_00835	3.03e-158	444.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli	91061|Bacilli	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	graR	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IGHDCBEA_01401	1046629.Ssal_00834	1.25e-127	363.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli	91061|Bacilli	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	iYO844.BSU22070	Pribosyltran
IGHDCBEA_01402	1046629.Ssal_00833	3.45e-283	776.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli	91061|Bacilli	F	xanthine permease	pbuX	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823	-	ko:K16169	-	-	-	-	ko00000,ko02000	2.A.40.3.1	-	iSB619.SA_RS02140	Xan_ur_permease
IGHDCBEA_01403	904306.HMPREF9192_1087	2.54e-80	239.0	2A1PZ@1|root,30PYD@2|Bacteria,1V4ZW@1239|Firmicutes	1239|Firmicutes	S	pyridoxamine 5'-phosphate oxidase	pdxH	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
IGHDCBEA_01404	435842.HMPREF0848_00914	0.0	946.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
IGHDCBEA_01405	1046629.Ssal_00830	2.93e-195	541.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K20373	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_3,HTH_31
IGHDCBEA_01406	1046629.Ssal_00829	5.45e-312	851.0	COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli	91061|Bacilli	V	Multidrug efflux pump	norM	GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
IGHDCBEA_01408	1046629.Ssal_00827	4.67e-232	638.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli	91061|Bacilli	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
IGHDCBEA_01409	1046629.Ssal_00826	7.42e-295	807.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli	91061|Bacilli	E	Component of the transport system for branched-chain amino acids	brnQ	GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
IGHDCBEA_01410	904306.HMPREF9192_1083	7.15e-230	632.0	COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli	91061|Bacilli	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU12020	PMI_typeI
IGHDCBEA_01411	1046629.Ssal_00824	1.03e-87	260.0	2C9NT@1|root,32V8Q@2|Bacteria,1VGVI@1239|Firmicutes,4IRUI@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3290
IGHDCBEA_01412	1046629.Ssal_00823	9.74e-138	390.0	COG2323@1|root,COG2323@2|Bacteria,1UYR2@1239|Firmicutes,4HGVG@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
IGHDCBEA_01413	1046629.Ssal_00822	9.97e-28	101.0	COG3237@1|root,COG3237@2|Bacteria,1VN9B@1239|Firmicutes,4I22P@91061|Bacilli	91061|Bacilli	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
IGHDCBEA_01414	1046629.Ssal_00820	9.9e-261	756.0	arCOG08054@1|root,2Z8AD@2|Bacteria,1TQ1J@1239|Firmicutes,4HDNN@91061|Bacilli	91061|Bacilli	S	Carbohydrate-binding domain-containing protein Cthe_2159	-	-	-	-	-	-	-	-	-	-	-	-	Cthe_2159
IGHDCBEA_01415	889204.HMPREF9423_1077	4.18e-67	207.0	COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,43G5A@68892|Streptococcus infantis	91061|Bacilli	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
IGHDCBEA_01416	1046629.Ssal_00818	9.72e-296	811.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli	91061|Bacilli	E	amino acid	yfnA	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
IGHDCBEA_01417	435842.HMPREF0848_00928	0.0	1750.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glyco_hydro_25,NLPC_P60,PG_binding_1
IGHDCBEA_01418	1046629.Ssal_00811	9.36e-106	305.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli	91061|Bacilli	O	Belongs to the glutathione peroxidase family	gpo	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
IGHDCBEA_01419	1046629.Ssal_00809	5.54e-54	171.0	COG4269@1|root,COG4269@2|Bacteria,1VA3P@1239|Firmicutes,4HKWF@91061|Bacilli	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
IGHDCBEA_01420	1046629.Ssal_00807	1.39e-56	176.0	COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HN2M@91061|Bacilli	91061|Bacilli	S	Sugar efflux transporter for intercellular exchange	-	-	-	-	-	-	-	-	-	-	-	-	MtN3_slv
IGHDCBEA_01421	888833.HMPREF9421_1062	7.71e-257	706.0	28K0P@1|root,2Z9QJ@2|Bacteria,1TSN2@1239|Firmicutes,4HU6K@91061|Bacilli	91061|Bacilli	P	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IGHDCBEA_01422	888048.HMPREF8577_0879	5.03e-157	441.0	COG1136@1|root,COG1136@2|Bacteria,1U3WD@1239|Firmicutes,4HV7M@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_01423	889204.HMPREF9423_0305	3.79e-125	357.0	COG1309@1|root,COG1309@2|Bacteria,1V2BY@1239|Firmicutes,4HPW3@91061|Bacilli	91061|Bacilli	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
IGHDCBEA_01424	435842.HMPREF0848_00939	2.56e-220	607.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli	91061|Bacilli	S	Aldo keto reductase	ydhF	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IGHDCBEA_01425	1114965.Spaf_1395	8.88e-270	741.0	COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli	91061|Bacilli	CP	ABC-type Na efflux pump, permease component	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
IGHDCBEA_01426	1046629.Ssal_00800	2.52e-206	571.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
IGHDCBEA_01428	1046629.Ssal_00798	1.19e-37	126.0	COG1476@1|root,COG1476@2|Bacteria,1VEZ1@1239|Firmicutes,4HNNM@91061|Bacilli	91061|Bacilli	K	transcriptional	XK27_07105	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
IGHDCBEA_01429	999425.HMPREF9186_00606	3.65e-47	153.0	2DU7U@1|root,33P99@2|Bacteria,1VQQU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01430	264199.stu1363	3.33e-140	396.0	COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli	91061|Bacilli	S	nitroreductase	XK27_02070	-	-	ko:K07078	-	-	-	-	ko00000	-	-	-	Nitroreductase
IGHDCBEA_01431	435842.HMPREF0848_00947	3.81e-189	527.0	COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli	91061|Bacilli	S	glyoxalase	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
IGHDCBEA_01432	904306.HMPREF9192_1076	2.25e-95	278.0	COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	ywnA_2	-	-	-	-	-	-	-	-	-	-	-	Rrf2
IGHDCBEA_01433	904306.HMPREF9192_1075	9.4e-197	546.0	COG4814@1|root,COG4814@2|Bacteria,1V13S@1239|Firmicutes,4HENM@91061|Bacilli	91061|Bacilli	E	Alpha/beta hydrolase of unknown function (DUF915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF915
IGHDCBEA_01434	904306.HMPREF9192_1074	3.12e-290	795.0	COG1455@1|root,COG1455@2|Bacteria,1V5SI@1239|Firmicutes,4HJTK@91061|Bacilli	91061|Bacilli	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	celB	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
IGHDCBEA_01435	1046629.Ssal_00789	7.61e-217	598.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	bcrA	-	-	ko:K01990,ko:K19309	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC_tran
IGHDCBEA_01436	904306.HMPREF9192_1072	1.06e-159	449.0	2EGU7@1|root,33AKD@2|Bacteria,1VMES@1239|Firmicutes,4HQPP@91061|Bacilli	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
IGHDCBEA_01437	1046629.Ssal_00787	5.75e-119	340.0	2DDQQ@1|root,2ZIXD@2|Bacteria,1V3FF@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01438	1046629.Ssal_00786	1.28e-180	506.0	COG0642@1|root,COG2205@2|Bacteria,1UYK9@1239|Firmicutes,4IPWV@91061|Bacilli	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,HisKA
IGHDCBEA_01439	1046629.Ssal_00785	2.47e-153	431.0	COG0745@1|root,COG0745@2|Bacteria,1TT2Z@1239|Firmicutes,4HDGH@91061|Bacilli	91061|Bacilli	T	Xre family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IGHDCBEA_01440	1046629.Ssal_00784	3.04e-141	399.0	COG0778@1|root,COG0778@2|Bacteria,1UXYI@1239|Firmicutes,4HBMN@91061|Bacilli	91061|Bacilli	C	nitroreductase	yodC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
IGHDCBEA_01441	1046629.Ssal_00783	3.88e-143	405.0	COG3619@1|root,COG3619@2|Bacteria,1V9ME@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
IGHDCBEA_01442	1046629.Ssal_00782	4.6e-53	166.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
IGHDCBEA_01443	1046629.Ssal_00781	2.97e-41	135.0	2DQ9B@1|root,335EQ@2|Bacteria,1VIWV@1239|Firmicutes,4HQTB@91061|Bacilli	91061|Bacilli	-	-	XK27_10490	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01444	1046629.Ssal_00780	9.86e-200	553.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli	91061|Bacilli	C	reductase	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IGHDCBEA_01445	904306.HMPREF9192_1063	4.75e-245	672.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
IGHDCBEA_01446	435842.HMPREF0848_00970	2.79e-302	830.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli	91061|Bacilli	G	UDPglucose--hexose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
IGHDCBEA_01447	435842.HMPREF0848_00971	7.78e-281	767.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli	91061|Bacilli	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
IGHDCBEA_01448	888833.HMPREF9421_1662	6.03e-186	523.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	galR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IGHDCBEA_01449	904306.HMPREF9192_1062	0.0	1043.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli	91061|Bacilli	G	COG0366 Glycosidases	dexB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.70	ko:K01215	-	-	-	-	ko00000,ko01000	-	-	-	Alpha-amylase,DUF3459,Malt_amylase_C
IGHDCBEA_01450	1034769.KB910518_gene3613	3.09e-245	686.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,4HEKC@91061|Bacilli,26TSJ@186822|Paenibacillaceae	91061|Bacilli	G	Alpha amylase, catalytic domain	-	-	2.4.1.329	ko:K21350	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase
IGHDCBEA_01451	1274374.CBLK010000070_gene1363	5.47e-121	357.0	COG0524@1|root,COG0524@2|Bacteria,1TQU6@1239|Firmicutes,4HTE0@91061|Bacilli,26V0D@186822|Paenibacillaceae	91061|Bacilli	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
IGHDCBEA_01452	1123311.KB904476_gene1298	3.35e-239	661.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	msmK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
IGHDCBEA_01453	1282665.H353_03773	6.5e-183	510.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,4HCEH@91061|Bacilli	91061|Bacilli	P	ABC-type sugar transport system, permease component	msmG	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IGHDCBEA_01454	888049.HMPREF8578_2007	2.53e-186	520.0	COG1175@1|root,COG1175@2|Bacteria,1TQB1@1239|Firmicutes,4HDV6@91061|Bacilli,1WPP8@1303|Streptococcus oralis	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	msmF	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IGHDCBEA_01455	864567.HMPREF8571_1568	6.75e-248	686.0	COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,4HCBS@91061|Bacilli,2TPMQ@28037|Streptococcus mitis	91061|Bacilli	G	Bacterial extracellular solute-binding protein	msmE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
IGHDCBEA_01456	435842.HMPREF0848_00973	0.0	1376.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli	91061|Bacilli	G	alpha-galactosidase	aga	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
IGHDCBEA_01457	435842.HMPREF0848_00974	1.13e-184	514.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,4ISD2@91061|Bacilli	91061|Bacilli	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
IGHDCBEA_01458	1046629.Ssal_00770	1.55e-21	93.6	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli	91061|Bacilli	G	COG0366 Glycosidases	dexB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.70	ko:K01215	-	-	-	-	ko00000,ko01000	-	-	-	Alpha-amylase,DUF3459,Malt_amylase_C
IGHDCBEA_01459	1046629.Ssal_00764	0.0	975.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,4HDNX@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0371 family	XK27_07020	-	-	-	-	-	-	-	-	-	-	-	DUF1846
IGHDCBEA_01460	1511.CLOST_2006	2.14e-06	50.8	2BYV2@1|root,33ICM@2|Bacteria,1VMF3@1239|Firmicutes,256VA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01461	1005705.HMPREF9967_1375	8.33e-296	806.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,4HCFN@91061|Bacilli,43GGC@68892|Streptococcus infantis	91061|Bacilli	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase,Rep_3
IGHDCBEA_01462	1005704.HMPREF9968_0101	3.87e-42	137.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,4HN2U@91061|Bacilli,1WQ85@1303|Streptococcus oralis	91061|Bacilli	S	Excisionase from transposon Tn916	xis	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
IGHDCBEA_01463	1033744.CAEL01000008_gene973	1.4e-48	154.0	2AJW5@1|root,31AIZ@2|Bacteria,1VKDU@1239|Firmicutes,25CSP@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
IGHDCBEA_01464	1005704.HMPREF9968_0102	3.84e-94	275.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,4HEE5@91061|Bacilli,1WQ18@1303|Streptococcus oralis	91061|Bacilli	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
IGHDCBEA_01465	1054460.SPPN_01500	2.99e-49	156.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,4HHCM@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IGHDCBEA_01466	1054460.SPPN_01495	0.0	1898.0	COG4644@1|root,COG4644@2|Bacteria,1TRGX@1239|Firmicutes,4HAJF@91061|Bacilli	91061|Bacilli	L	Transposase and inactivated derivatives, TnpA family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
IGHDCBEA_01467	1121864.OMO_00467	1.67e-123	352.0	COG1961@1|root,COG1961@2|Bacteria,1UZT3@1239|Firmicutes,4HEGY@91061|Bacilli,4B6EF@81852|Enterococcaceae	91061|Bacilli	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
IGHDCBEA_01468	1158604.I591_02847	4.63e-24	90.5	2A8RU@1|root,30XUI@2|Bacteria,1VHZC@1239|Firmicutes,4IBX8@91061|Bacilli,4B49K@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01469	562982.HMPREF0432_00430	1.28e-173	484.0	COG0030@1|root,COG0030@2|Bacteria,1UY9S@1239|Firmicutes,4HC16@91061|Bacilli	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	ermA	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
IGHDCBEA_01470	1123318.KB904586_gene441	0.0	1272.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4HAS9@91061|Bacilli	91061|Bacilli	J	elongation factor G	XK27_03330	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
IGHDCBEA_01471	391295.SSU05_0923	8.14e-217	598.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,4HA00@91061|Bacilli	91061|Bacilli	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
IGHDCBEA_01472	1033744.CAEL01000008_gene978	3.21e-243	667.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,22IG3@1570339|Peptoniphilaceae	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
IGHDCBEA_01473	1033744.CAEL01000008_gene979	0.0	1278.0	COG4980@1|root,COG4980@2|Bacteria,1TQCQ@1239|Firmicutes,25EX1@186801|Clostridia	186801|Clostridia	S	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01474	1005704.HMPREF9968_0186	0.0	1587.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,4HBZY@91061|Bacilli,1WQ19@1303|Streptococcus oralis	91061|Bacilli	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
IGHDCBEA_01475	1005704.HMPREF9968_0187	5.98e-116	332.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,4HF9Q@91061|Bacilli,1WQ0M@1303|Streptococcus oralis	91061|Bacilli	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
IGHDCBEA_01476	1005704.HMPREF9968_0188	1.42e-117	336.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,4HDCV@91061|Bacilli,1WQ5N@1303|Streptococcus oralis	91061|Bacilli	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
IGHDCBEA_01477	1005704.HMPREF9968_0189	3.41e-41	135.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,4HM05@91061|Bacilli,1WQ8B@1303|Streptococcus oralis	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01478	1005704.HMPREF9968_0190	1.82e-297	810.0	COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,4HCHD@91061|Bacilli,1WQ1T@1303|Streptococcus oralis	91061|Bacilli	K	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Omega_Repress,Rep_trans
IGHDCBEA_01479	1005704.HMPREF9968_0191	0.0	916.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,4HB44@91061|Bacilli,1WQ22@1303|Streptococcus oralis	91061|Bacilli	D	Domain of unknown function DUF87	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
IGHDCBEA_01480	1005704.HMPREF9968_0192	1.39e-83	247.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,4HG1A@91061|Bacilli,1WQ64@1303|Streptococcus oralis	91061|Bacilli	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
IGHDCBEA_01481	1005704.HMPREF9968_0193	1.6e-69	209.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,4HH9J@91061|Bacilli,1WQ6F@1303|Streptococcus oralis	91061|Bacilli	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
IGHDCBEA_01482	904306.HMPREF9192_1054	6.28e-203	567.0	COG4097@1|root,COG4097@2|Bacteria,1V0GF@1239|Firmicutes	1239|Firmicutes	P	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
IGHDCBEA_01483	904306.HMPREF9192_1054	9.96e-41	144.0	COG4097@1|root,COG4097@2|Bacteria,1V0GF@1239|Firmicutes	1239|Firmicutes	P	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
IGHDCBEA_01484	1046629.Ssal_00760	1.34e-232	640.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli	91061|Bacilli	S	oxidoreductase	XK27_10475	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
IGHDCBEA_01485	1046629.Ssal_00759	2e-77	231.0	COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes	1239|Firmicutes	S	dihydroxyacetone kinase, phosphotransfer subunit	dhaM	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
IGHDCBEA_01486	1046629.Ssal_00758	6.69e-122	349.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli	91061|Bacilli	S	Dihydroxyacetone kinase	dhaL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
IGHDCBEA_01487	1046629.Ssal_00757	1.01e-228	630.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4H9VS@91061|Bacilli	91061|Bacilli	G	Dihydroxyacetone kinase	dhaK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
IGHDCBEA_01488	1046629.Ssal_00756	1.27e-289	792.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TSE8@1239|Firmicutes	1239|Firmicutes	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,ThrE,ThrE_2
IGHDCBEA_01489	1046629.Ssal_00755	0.0	2209.0	COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat	tcdB	-	-	ko:K11063	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
IGHDCBEA_01490	927666.SOR_0713	8.83e-47	152.0	2DKHV@1|root,309HT@2|Bacteria,1U54E@1239|Firmicutes,4I1BW@91061|Bacilli	91061|Bacilli	S	Immunity protein 41	-	-	-	-	-	-	-	-	-	-	-	-	Imm41
IGHDCBEA_01491	1069533.Sinf_1729	9.81e-13	66.2	2EGBF@1|root,33A3A@2|Bacteria,1VP2X@1239|Firmicutes,4HS3U@91061|Bacilli	91061|Bacilli	S	Enterocin A Immunity	-	-	-	-	-	-	-	-	-	-	-	-	EntA_Immun
IGHDCBEA_01492	1316408.HSISM1_120	8.26e-247	677.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HDUZ@91061|Bacilli	91061|Bacilli	V	LD-carboxypeptidase	mccF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
IGHDCBEA_01493	469609.HMPREF0847_01534	1.07e-14	75.9	COG5658@1|root,COG5658@2|Bacteria	2|Bacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
IGHDCBEA_01494	1046629.Ssal_00745	1.21e-58	181.0	COG0640@1|root,COG0640@2|Bacteria,1UKJV@1239|Firmicutes,4ITJ6@91061|Bacilli	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
IGHDCBEA_01495	1046629.Ssal_00744	1.22e-146	416.0	COG4377@1|root,COG4377@2|Bacteria	2|Bacteria	S	Putative membrane peptidase family (DUF2324)	yhfC	-	-	-	-	-	-	-	-	-	-	-	DUF2324
IGHDCBEA_01496	1046629.Ssal_00742	0.0	2857.0	COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli	91061|Bacilli	M	KxYKxGKxW signal domain protein	-	GO:0005575,GO:0005576	2.4.1.5	ko:K00689	ko00500,ko02020,map00500,map02020	-	R02120,R06066	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Big_2,CW_binding_1,Glyco_hydro_70
IGHDCBEA_01498	1046629.Ssal_00740	0.0	1031.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,NLPC_P60,PG_binding_1
IGHDCBEA_01499	1046629.Ssal_00738	0.0	2745.0	COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli	91061|Bacilli	M	KxYKxGKxW signal domain protein	-	GO:0005575,GO:0005576	2.4.1.5	ko:K00689	ko00500,ko02020,map00500,map02020	-	R02120,R06066	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Big_2,CW_binding_1,Glyco_hydro_70
IGHDCBEA_01500	1046629.Ssal_00737	0.0	1695.0	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,NLPC_P60,PG_binding_1
IGHDCBEA_01501	1046629.Ssal_00734	2.38e-38	144.0	COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat	tcdB	-	-	ko:K11063	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
IGHDCBEA_01504	1046629.Ssal_01816	7.67e-139	393.0	2F8BM@1|root,340QP@2|Bacteria,1W4V4@1239|Firmicutes,4HR72@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF1803)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1803
IGHDCBEA_01505	1046629.Ssal_01817	1.65e-213	590.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli	91061|Bacilli	C	inorganic pyrophosphatase	ppaC	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DHH,DHHA2
IGHDCBEA_01506	1046629.Ssal_01222	2.44e-82	248.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	glnQ	-	-	ko:K10041	ko02010,map02010	M00228	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IGHDCBEA_01507	435842.HMPREF0848_00558	2.27e-183	511.0	COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli	91061|Bacilli	ET	ABC-type amino acid transport signal transduction systems, periplasmic component domain	peb1A	-	-	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	M00228,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
IGHDCBEA_01508	1046629.Ssal_02147	2.85e-68	208.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
IGHDCBEA_01509	1046629.Ssal_00534	3.99e-181	504.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,4HDSE@91061|Bacilli	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
IGHDCBEA_01510	1046629.Ssal_01224	4.06e-60	190.0	COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HE9C@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	XK27_07620	-	-	ko:K10040	ko02010,map02010	M00228	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
IGHDCBEA_01511	322159.STER_0763	1.6e-148	423.0	COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes	1239|Firmicutes	L	Transposase	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IGHDCBEA_01521	1046629.Ssal_00123	6.68e-85	253.0	COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,4HBWU@91061|Bacilli	91061|Bacilli	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
IGHDCBEA_01522	435842.HMPREF0848_01930	8.92e-87	255.0	COG1393@1|root,COG1393@2|Bacteria,1VYBB@1239|Firmicutes,4HWYC@91061|Bacilli	91061|Bacilli	P	Belongs to the ArsC family	spxA_2	-	1.20.4.1	ko:K00537,ko:K16509	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
IGHDCBEA_01523	1046629.Ssal_00039	3.45e-86	265.0	COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes	1239|Firmicutes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IGHDCBEA_01524	1046629.Ssal_00208	1.33e-101	304.0	COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes	1239|Firmicutes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
IGHDCBEA_01525	1046629.Ssal_01369	1.29e-235	647.0	COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli	91061|Bacilli	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdF	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iSB619.SA_RS03915,iYO844.BSU17390	Ribonuc_red_sm
IGHDCBEA_01526	1046629.Ssal_01368	0.0	1430.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli	91061|Bacilli	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdE	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iYO844.BSU17380	RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN
IGHDCBEA_01527	264199.stu1269	3.36e-46	148.0	COG0695@1|root,COG0695@2|Bacteria,1VEFX@1239|Firmicutes,4HNUX@91061|Bacilli	91061|Bacilli	O	Glutaredoxin	nrdH	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
IGHDCBEA_01528	1046629.Ssal_01366	0.0	1752.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli	91061|Bacilli	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
IGHDCBEA_01529	1046629.Ssal_01365	1e-269	738.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli	91061|Bacilli	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
IGHDCBEA_01530	1046629.Ssal_01364	2.42e-281	769.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli	91061|Bacilli	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
IGHDCBEA_01531	1046629.Ssal_01363	2.72e-51	162.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli	91061|Bacilli	G	phosphocarrier protein Hpr	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IGHDCBEA_01532	1046629.Ssal_01362	0.0	1100.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli	91061|Bacilli	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
IGHDCBEA_01533	1046629.Ssal_01360	0.0	917.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	gapN	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
IGHDCBEA_01534	1046629.Ssal_01359	6.48e-207	571.0	COG2819@1|root,COG2819@2|Bacteria,1UZZZ@1239|Firmicutes,4HCWE@91061|Bacilli	91061|Bacilli	S	Putative esterase	XK27_05670	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
IGHDCBEA_01535	1046629.Ssal_01358	1.52e-195	540.0	COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,4HB4B@91061|Bacilli	91061|Bacilli	S	Esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
IGHDCBEA_01536	1046629.Ssal_01357	3.46e-288	786.0	COG1181@1|root,COG1181@2|Bacteria,1UIK5@1239|Firmicutes,4HBFS@91061|Bacilli	91061|Bacilli	M	carbamoylphosphate synthase large subunit	XK27_05680	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,CPSase_L_D2
IGHDCBEA_01537	1046629.Ssal_01356	2.3e-236	652.0	COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli	91061|Bacilli	L	DEAD DEAH box helicase	yfmL	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
IGHDCBEA_01538	1046629.Ssal_01355	5.27e-147	414.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli	91061|Bacilli	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
IGHDCBEA_01539	435842.HMPREF0848_00416	0.0	1166.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IGHDCBEA_01540	435842.HMPREF0848_00417	7.55e-53	166.0	COG4298@1|root,COG4298@2|Bacteria,1VCHF@1239|Firmicutes,4HMAW@91061|Bacilli	91061|Bacilli	S	yiaA/B two helix domain	-	-	-	-	-	-	-	-	-	-	-	-	YiaAB
IGHDCBEA_01541	1046629.Ssal_01352	1.28e-170	476.0	COG0596@1|root,COG0596@2|Bacteria,1V02M@1239|Firmicutes,4HN2K@91061|Bacilli	91061|Bacilli	S	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
IGHDCBEA_01542	1046629.Ssal_01351	0.0	1619.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli	91061|Bacilli	J	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	iYO844.BG12900	DUF2156,LPG_synthase_TM
IGHDCBEA_01543	1046629.Ssal_01350	3.57e-193	535.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli	91061|Bacilli	S	glutamine amidotransferase	cobQ	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
IGHDCBEA_01544	1046629.Ssal_01349	0.0	883.0	COG0771@1|root,COG0771@2|Bacteria,1UHPI@1239|Firmicutes,4HVP0@91061|Bacilli	91061|Bacilli	M	Mur ligase, middle domain protein	murE2	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF1727,Mur_ligase_M
IGHDCBEA_01545	904306.HMPREF9192_1521	4.57e-189	526.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli	91061|Bacilli	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
IGHDCBEA_01546	1046629.Ssal_01347	1.75e-209	581.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
IGHDCBEA_01547	1046629.Ssal_01346	3.69e-316	862.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli	91061|Bacilli	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11275	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IGHDCBEA_01548	1046629.Ssal_01345	2.6e-86	255.0	COG2246@1|root,COG2246@2|Bacteria,1VMS6@1239|Firmicutes,4HNB7@91061|Bacilli	91061|Bacilli	S	GtrA-like protein	mesH	-	-	-	-	-	-	-	-	-	-	-	GtrA
IGHDCBEA_01551	759913.SDSE_2235	3.77e-16	74.3	29I0Q@1|root,304XU@2|Bacteria,1TXE0@1239|Firmicutes,4I6C6@91061|Bacilli,1MA25@119603|Streptococcus dysgalactiae group	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01553	1123314.AUIO01000005_gene82	1.56e-132	396.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,4HCHZ@91061|Bacilli	91061|Bacilli	T	Virulence-associated protein E	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	VirE
IGHDCBEA_01554	322159.STER_0820	5.06e-180	504.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
IGHDCBEA_01555	1214217.ALNF01000036_gene1690	1.35e-28	105.0	2ARDV@1|root,31GPY@2|Bacteria,1U98K@1239|Firmicutes,4IJB7@91061|Bacilli,1WU20@1307|Streptococcus suis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01560	1123299.AUKZ01000002_gene644	1.13e-27	101.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
IGHDCBEA_01561	563038.HMPREF0851_01053	1.7e-11	67.8	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli	91061|Bacilli	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IGHDCBEA_01562	322159.STER_0829	1.87e-240	665.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
IGHDCBEA_01563	904306.HMPREF9192_1525	1.38e-155	437.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli	91061|Bacilli	S	SAM-dependent methyltransferase	trmK	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TrmK
IGHDCBEA_01564	1046629.Ssal_01343	4.3e-185	514.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli	91061|Bacilli	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
IGHDCBEA_01565	1046629.Ssal_01342	1.41e-97	290.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli	91061|Bacilli	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
IGHDCBEA_01566	1046629.Ssal_01342	6.43e-67	209.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli	91061|Bacilli	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
IGHDCBEA_01567	1046629.Ssal_01341	3.8e-252	692.0	COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli	91061|Bacilli	E	oxidoreductase	yurR	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
IGHDCBEA_01568	1046629.Ssal_01340	0.0	896.0	COG4099@1|root,COG4099@2|Bacteria,1TRER@1239|Firmicutes,4IQ64@91061|Bacilli	91061|Bacilli	S	phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd,Peptidase_S9
IGHDCBEA_01569	1046629.Ssal_01339	7.83e-206	569.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli	91061|Bacilli	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
IGHDCBEA_01570	1046629.Ssal_01338	3.91e-142	400.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli	91061|Bacilli	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rmlC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
IGHDCBEA_01571	435842.HMPREF0848_00434	3.17e-262	717.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
IGHDCBEA_01575	1046629.Ssal_01332	1.62e-277	758.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli	91061|Bacilli	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
IGHDCBEA_01576	1046629.Ssal_01331	1.69e-179	499.0	COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli	91061|Bacilli	I	Acyl-ACP thioesterase	fat	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
IGHDCBEA_01577	1046629.Ssal_01330	1.23e-177	495.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli	91061|Bacilli	G	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro	nagD	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
IGHDCBEA_01578	435842.HMPREF0848_00440	1.3e-153	431.0	COG4478@1|root,COG4478@2|Bacteria,1VGZ1@1239|Firmicutes,4HNTM@91061|Bacilli	91061|Bacilli	S	tigr01906	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
IGHDCBEA_01579	1046629.Ssal_01328	3.69e-178	496.0	COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HGYX@91061|Bacilli	91061|Bacilli	E	Histidinol phosphatase and related hydrolases of the PHP family	hisJ	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
IGHDCBEA_01580	1046629.Ssal_01327	4.59e-198	551.0	COG4632@1|root,COG4632@2|Bacteria,1TR6Z@1239|Firmicutes,4HGB0@91061|Bacilli	91061|Bacilli	G	Exopolysaccharide biosynthesis protein	XK27_08080	-	-	-	-	-	-	-	-	-	-	-	NAGPA
IGHDCBEA_01581	435842.HMPREF0848_00449	1.82e-80	239.0	2EJUK@1|root,33DJ8@2|Bacteria,1VM50@1239|Firmicutes	1239|Firmicutes	-	-	XK27_08085	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01582	1046629.Ssal_01325	3.77e-246	676.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli	91061|Bacilli	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IGHDCBEA_01583	435842.HMPREF0848_00451	2.68e-227	627.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli	91061|Bacilli	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
IGHDCBEA_01584	1046629.Ssal_01323	2.93e-151	425.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli	91061|Bacilli	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,tRNA-synt_His
IGHDCBEA_01585	1046629.Ssal_01322	5.08e-299	816.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli	91061|Bacilli	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU34910	Histidinol_dh
IGHDCBEA_01586	1046629.Ssal_01321	1.66e-137	389.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli	91061|Bacilli	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14130	IGPD
IGHDCBEA_01587	1046629.Ssal_01320	8.15e-142	400.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
IGHDCBEA_01588	1046629.Ssal_01319	1.68e-166	466.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli	91061|Bacilli	E	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
IGHDCBEA_01589	1046629.Ssal_01318	1.33e-174	487.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli	91061|Bacilli	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14115	His_biosynth
IGHDCBEA_01590	435842.HMPREF0848_00458	8.55e-80	236.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli	91061|Bacilli	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
IGHDCBEA_01591	1046629.Ssal_01315	1.27e-66	202.0	COG0140@1|root,COG0140@2|Bacteria	2|Bacteria	E	phosphoribosyl-ATP diphosphatase activity	hisE	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31,5.3.1.16	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037,R04640	RC00002,RC00945,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
IGHDCBEA_01593	1046629.Ssal_01313	5.62e-134	382.0	COG1285@1|root,COG1285@2|Bacteria,1V1GI@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	XK27_05505	-	-	-	-	-	-	-	-	-	-	-	DUF4956
IGHDCBEA_01594	435842.HMPREF0848_00461	3.98e-184	512.0	COG5036@1|root,COG5036@2|Bacteria,1V1FZ@1239|Firmicutes,4HJFI@91061|Bacilli	91061|Bacilli	P	molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	VTC
IGHDCBEA_01595	1046629.Ssal_01311	3.4e-164	475.0	arCOG08054@1|root,2Z8AD@2|Bacteria,1TZ8N@1239|Firmicutes,4HV65@91061|Bacilli	91061|Bacilli	S	Carbohydrate-binding domain-containing protein Cthe_2159	-	-	-	-	-	-	-	-	-	-	-	-	Cthe_2159
IGHDCBEA_01596	1046629.Ssal_01310	4.79e-228	630.0	COG1216@1|root,COG2246@1|root,COG1216@2|Bacteria,COG2246@2|Bacteria,1UIHV@1239|Firmicutes,4ISID@91061|Bacilli	91061|Bacilli	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
IGHDCBEA_01597	1046629.Ssal_01309	0.0	2643.0	COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli	91061|Bacilli	M	KxYKxGKxW signal domain protein	-	-	2.4.1.5	ko:K00689	ko00500,ko02020,map00500,map02020	-	R02120,R06066	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Big_2,CW_binding_1,Glyco_hydro_70
IGHDCBEA_01598	1046629.Ssal_01308	0.0	2808.0	COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli	91061|Bacilli	M	KxYKxGKxW signal domain protein	-	-	2.4.1.5	ko:K00689	ko00500,ko02020,map00500,map02020	-	R02120,R06066	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Big_2,CW_binding_1,Glyco_hydro_70
IGHDCBEA_01599	1046629.Ssal_01307	0.0	3015.0	COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli	91061|Bacilli	M	KxYKxGKxW signal domain protein	-	-	2.4.1.5	ko:K00689	ko00500,ko02020,map00500,map02020	-	R02120,R06066	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Big_2,CW_binding_1,Glyco_hydro_70
IGHDCBEA_01600	904306.HMPREF9192_1554	1.18e-310	850.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli	91061|Bacilli	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
IGHDCBEA_01601	1046629.Ssal_01305	1.06e-283	778.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli	91061|Bacilli	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
IGHDCBEA_01602	904306.HMPREF9192_1556	1.39e-143	405.0	COG4468@1|root,COG4468@2|Bacteria,1VY8D@1239|Firmicutes,4HXPD@91061|Bacilli	91061|Bacilli	G	UDPglucose--hexose-1-phosphate uridylyltransferase	XK27_05445	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01603	904306.HMPREF9192_1557	2.99e-220	607.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli	91061|Bacilli	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
IGHDCBEA_01604	904306.HMPREF9192_1558	8.29e-175	488.0	COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
IGHDCBEA_01605	904306.HMPREF9192_1559	1.26e-87	258.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	GnaT	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
IGHDCBEA_01606	1046629.Ssal_01299	0.0	1441.0	COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
IGHDCBEA_01607	904306.HMPREF9192_1561	7.52e-121	345.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli	91061|Bacilli	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
IGHDCBEA_01608	1046629.Ssal_01297	2.7e-230	633.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli	91061|Bacilli	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metA	GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
IGHDCBEA_01609	1046629.Ssal_01296	6.09e-161	451.0	COG3935@1|root,COG3935@2|Bacteria	2|Bacteria	-	-	dnaD	-	-	ko:K02086	-	-	-	-	ko00000	-	-	-	DnaB_2
IGHDCBEA_01610	1046629.Ssal_01295	9.12e-154	431.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli	91061|Bacilli	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
IGHDCBEA_01612	1046629.Ssal_01292	2.33e-292	800.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
IGHDCBEA_01613	435842.HMPREF0848_00499	2.44e-40	133.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes	1239|Firmicutes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
IGHDCBEA_01614	1046629.Ssal_01290	2.23e-201	558.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli	91061|Bacilli	H	Belongs to the FPP GGPP synthase family	ispA	GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
IGHDCBEA_01615	1046629.Ssal_01289	4.65e-191	531.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli	91061|Bacilli	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
IGHDCBEA_01616	1046629.Ssal_01288	1.26e-96	281.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli	91061|Bacilli	K	Regulates arginine biosynthesis genes	argR2	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
IGHDCBEA_01617	1046629.Ssal_01287	0.0	1043.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli	91061|Bacilli	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
IGHDCBEA_01618	1046629.Ssal_01286	7.89e-185	515.0	COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli	91061|Bacilli	S	DegV family	WQ51_01275	-	-	-	-	-	-	-	-	-	-	-	DegV
IGHDCBEA_01619	1046629.Ssal_01285	5.29e-205	567.0	COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli	91061|Bacilli	E	COG2755 Lysophospholipase L1 and related esterases	XK27_03630	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IGHDCBEA_01620	1046629.Ssal_01284	2.35e-126	360.0	COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	ypmS	-	-	-	-	-	-	-	-	-	-	-	DUF2140
IGHDCBEA_01621	1046629.Ssal_01283	3.1e-52	165.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
IGHDCBEA_01623	1046629.Ssal_01281	1.44e-228	629.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HBFE@91061|Bacilli	91061|Bacilli	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
IGHDCBEA_01624	904306.HMPREF9192_1578	1.24e-168	470.0	COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli	91061|Bacilli	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
IGHDCBEA_01625	1046629.Ssal_01276	0.0	1000.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli	91061|Bacilli	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10690,iYO844.BSU28280	HMGL-like,LeuA_dimer
IGHDCBEA_01626	1046629.Ssal_01275	1.36e-241	664.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli	91061|Bacilli	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU28270	Iso_dh
IGHDCBEA_01627	322159.STER_1169	1.41e-49	158.0	COG3326@1|root,COG3326@2|Bacteria	2|Bacteria	L	Membrane	ysdA	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
IGHDCBEA_01628	1046629.Ssal_01273	0.0	951.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10700	Aconitase
IGHDCBEA_01629	1046629.Ssal_01272	5.58e-146	410.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
IGHDCBEA_01630	1046629.Ssal_01271	0.0	1998.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
IGHDCBEA_01631	1046629.Ssal_01270	6.69e-239	657.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli	91061|Bacilli	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	iYO844.BSU29190	PFK
IGHDCBEA_01632	1046629.Ssal_01268	0.0	957.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli	91061|Bacilli	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
IGHDCBEA_01633	1046629.Ssal_00984	4.06e-40	137.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,4HDZ0@91061|Bacilli	91061|Bacilli	L	COG1943 Transposase and inactivated derivatives	isplu5A	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
IGHDCBEA_01635	1046629.Ssal_01265	2.78e-228	630.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HE7G@91061|Bacilli	91061|Bacilli	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
IGHDCBEA_01636	1046629.Ssal_01264	1.37e-190	531.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli	91061|Bacilli	S	Belongs to the binding-protein-dependent transport system permease family	XK27_08840	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
IGHDCBEA_01637	1046629.Ssal_01263	1.09e-173	485.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	XK27_08845	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
IGHDCBEA_01638	1046629.Ssal_01262	0.0	1066.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnjB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
IGHDCBEA_01639	1046629.Ssal_01260	3.57e-192	532.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli	91061|Bacilli	S	Esterase	estA	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
IGHDCBEA_01640	1046629.Ssal_01259	3.8e-163	457.0	COG5549@1|root,COG5549@2|Bacteria,1VW9X@1239|Firmicutes,4HWF8@91061|Bacilli	91061|Bacilli	O	Zinc-dependent metalloprotease	XK27_08875	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
IGHDCBEA_01641	996306.SSUR61_0275	4.1e-25	99.0	29R1H@1|root,30C2M@2|Bacteria,1U92D@1239|Firmicutes,4IJ2X@91061|Bacilli,1WTJN@1307|Streptococcus suis	91061|Bacilli	-	-	XK27_08880	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01642	1046629.Ssal_01256	2.45e-98	286.0	COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli	91061|Bacilli	C	Flavodoxin	ykuP	-	-	ko:K03839	-	-	-	-	ko00000	-	-	-	Flavodoxin_1
IGHDCBEA_01643	1046629.Ssal_01255	0.0	966.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli	91061|Bacilli	P	Chloride transporter, ClC family	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
IGHDCBEA_01644	264199.stu1181	1.05e-54	171.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	pheA	GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715,R01728	RC00125,RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_2667	ACT,CM_2,PDT
IGHDCBEA_01645	1046629.Ssal_01253	3.91e-270	742.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes	1239|Firmicutes	P	Chloride transporter ClC family	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
IGHDCBEA_01646	1046629.Ssal_01252	2.33e-74	223.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
IGHDCBEA_01648	64186.O21990_9CAUD	1.93e-91	276.0	4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses  no RNA stage,4QPDM@28883|Caudovirales,4QKN9@10699|Siphoviridae	10699|Siphoviridae	S	Phage integrase family	-	GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01649	1046629.Ssal_01249	3.78e-129	378.0	COG2369@1|root,COG2369@2|Bacteria	2|Bacteria	K	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,Ntox50,Phage_Mu_F
IGHDCBEA_01650	1118055.CAGU01000029_gene13	2.99e-25	98.6	2E5Y5@1|root,330MW@2|Bacteria,1VEY6@1239|Firmicutes,24VDE@186801|Clostridia	186801|Clostridia	S	YjcQ protein	-	-	-	-	-	-	-	-	-	-	-	-	YjcQ
IGHDCBEA_01651	585203.SMSK564_1007	2.62e-21	85.1	2BGC4@1|root,3099Z@2|Bacteria,1U4P5@1239|Firmicutes,4IEEW@91061|Bacilli,2TQ3T@28037|Streptococcus mitis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01653	1046629.Ssal_01245	5.66e-29	103.0	2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3042)	WQ51_02665	-	-	-	-	-	-	-	-	-	-	-	DUF3042
IGHDCBEA_01654	1046629.Ssal_01244	9.43e-205	568.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli	91061|Bacilli	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
IGHDCBEA_01655	1046629.Ssal_01243	6.2e-114	327.0	COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli	91061|Bacilli	T	GAF domain-containing protein	ytsP	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
IGHDCBEA_01656	1046629.Ssal_01242	0.0	1051.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli	91061|Bacilli	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
IGHDCBEA_01657	1046629.Ssal_01240	8.3e-224	617.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli	91061|Bacilli	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
IGHDCBEA_01658	1046629.Ssal_01239	7.32e-270	740.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli	91061|Bacilli	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
IGHDCBEA_01665	1046629.Ssal_00666	2.29e-237	661.0	COG0488@1|root,COG0488@2|Bacteria,1TU6J@1239|Firmicutes,4HDY2@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	XK27_10075	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
IGHDCBEA_01666	435842.HMPREF0848_01041	0.0	1156.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	ndvA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_01667	435842.HMPREF0848_01042	0.0	1042.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_01668	1046629.Ssal_00663	0.0	1470.0	COG1181@1|root,COG2918@1|root,COG1181@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli	91061|Bacilli	H	Belongs to the glutamate--cysteine ligase type 1 family	gshF	-	6.3.2.2	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	M00118,M00582	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ATP-grasp_3,Dala_Dala_lig_C,GARS_A,Glu_cys_ligase
IGHDCBEA_01670	1046629.Ssal_00660	0.0	982.0	2DI63@1|root,32UAI@2|Bacteria,1VBKU@1239|Firmicutes,4HUJH@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1310,DUF3114
IGHDCBEA_01671	1046629.Ssal_00659	3.65e-128	364.0	COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,4HPE4@91061|Bacilli	91061|Bacilli	K	Acetyltransferase GNAT Family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
IGHDCBEA_01672	1046629.Ssal_00658	0.0	1593.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli	91061|Bacilli	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	iYO844.BSU30940	Phosphorylase
IGHDCBEA_01673	1046629.Ssal_00657	0.0	968.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli	91061|Bacilli	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
IGHDCBEA_01674	1046629.Ssal_00656	1.39e-230	639.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli	91061|Bacilli	G	glucose-1-phosphate adenylyltransferase	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
IGHDCBEA_01675	1046629.Ssal_00655	3.1e-251	692.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli	91061|Bacilli	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
IGHDCBEA_01676	1046629.Ssal_00654	0.0	1319.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli	91061|Bacilli	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
IGHDCBEA_01677	1046629.Ssal_00653	0.0	1459.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli	91061|Bacilli	G	belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,PUD
IGHDCBEA_01678	1046629.Ssal_00651	0.0	1466.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
IGHDCBEA_01679	1046629.Ssal_00650	6.99e-242	664.0	COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli	91061|Bacilli	C	Ferredoxin--NADP reductase	yumC	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	iYO844.BSU32110	Pyr_redox_2
IGHDCBEA_01680	1046629.Ssal_00649	1.98e-174	486.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
IGHDCBEA_01681	1046629.Ssal_00648	9.14e-122	347.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
IGHDCBEA_01684	904306.HMPREF9192_0962	1.9e-146	413.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli	91061|Bacilli	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
IGHDCBEA_01685	904306.HMPREF9192_0961	2.53e-221	612.0	COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli	91061|Bacilli	T	Histidine kinase	vraS	-	2.7.13.3	ko:K07681,ko:K11617	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
IGHDCBEA_01686	435842.HMPREF0848_01061	4.94e-151	426.0	COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli	91061|Bacilli	S	Membrane	yvqF	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
IGHDCBEA_01687	1046629.Ssal_00644	1.27e-107	315.0	COG1226@1|root,COG1226@2|Bacteria,1V285@1239|Firmicutes,4I17E@91061|Bacilli	91061|Bacilli	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
IGHDCBEA_01688	1046629.Ssal_00644	1.96e-22	92.8	COG1226@1|root,COG1226@2|Bacteria,1V285@1239|Firmicutes,4I17E@91061|Bacilli	91061|Bacilli	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
IGHDCBEA_01689	1046629.Ssal_00643	0.0	1078.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
IGHDCBEA_01690	1046629.Ssal_00642	1.14e-176	493.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli	91061|Bacilli	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
IGHDCBEA_01691	1046629.Ssal_00641	4.1e-308	841.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli	91061|Bacilli	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
IGHDCBEA_01692	904306.HMPREF9192_0955	8.23e-219	604.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
IGHDCBEA_01693	1046629.Ssal_00638	0.0	1529.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
IGHDCBEA_01694	1046629.Ssal_00637	1.37e-61	189.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
IGHDCBEA_01695	1046629.Ssal_00636	3.57e-144	407.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli	91061|Bacilli	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15680	Guanylate_kin
IGHDCBEA_01696	1046629.Ssal_00633	1.6e-273	755.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
IGHDCBEA_01697	1046629.Ssal_00632	4.13e-188	523.0	COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HGA9@91061|Bacilli	91061|Bacilli	S	overlaps another CDS with the same product name	XK27_02985	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IGHDCBEA_01698	1046629.Ssal_00631	6.37e-188	522.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,4IPK2@91061|Bacilli	91061|Bacilli	S	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IGHDCBEA_01699	1046629.Ssal_00630	1.16e-81	242.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli	91061|Bacilli	K	Transcriptional	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
IGHDCBEA_01700	1046629.Ssal_00629	3.38e-158	444.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HGHM@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	skfE	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_01701	1046629.Ssal_00628	4.51e-166	466.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes	1239|Firmicutes	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01702	1046629.Ssal_00627	2.87e-218	602.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HCM4@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	amiF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
IGHDCBEA_01703	904306.HMPREF9192_0944	1.98e-258	708.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4H9MR@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	amiE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
IGHDCBEA_01704	1046629.Ssal_00625	7.82e-211	583.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HE8S@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	amiD	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
IGHDCBEA_01705	1046629.Ssal_00624	0.0	957.0	COG0601@1|root,COG0601@2|Bacteria,1UY5U@1239|Firmicutes,4HEZK@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	amiC	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
IGHDCBEA_01706	1046629.Ssal_00622	0.0	1053.0	COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli	91061|Bacilli	E	ABC transporter, substrate-binding protein, family 5	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
IGHDCBEA_01707	1046629.Ssal_00622	0.0	1299.0	COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli	91061|Bacilli	E	ABC transporter, substrate-binding protein, family 5	amiA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
IGHDCBEA_01708	1046629.Ssal_00621	2.22e-231	637.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli	91061|Bacilli	C	phosphate acetyltransferase	pta	-	2.3.1.8,3.6.3.21	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00236,M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	iSB619.SA_RS03155	PTA_PTB
IGHDCBEA_01709	904306.HMPREF9192_0939	3.5e-218	601.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	yjbO	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
IGHDCBEA_01710	264199.stu1457	5.67e-196	543.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli	91061|Bacilli	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS04895	NAD_kinase
IGHDCBEA_01711	1046629.Ssal_00618	2.5e-155	436.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli	91061|Bacilli	S	Gtp pyrophosphokinase	yjbM	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
IGHDCBEA_01712	904306.HMPREF9192_0936	9.61e-131	371.0	COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli	91061|Bacilli	S	Adenylate cyclase	yjbK	-	-	-	-	-	-	-	-	-	-	-	CYTH
IGHDCBEA_01713	1046629.Ssal_00616	3.37e-224	619.0	COG0462@1|root,COG0462@2|Bacteria,1TQ4I@1239|Firmicutes,4HDRN@91061|Bacilli	91061|Bacilli	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs2	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
IGHDCBEA_01714	1046629.Ssal_00615	8.41e-260	712.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli	91061|Bacilli	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IGHDCBEA_01715	1046629.Ssal_00614	1.52e-79	236.0	2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli	91061|Bacilli	S	Putative amino acid metabolism	XK27_04120	-	-	-	-	-	-	-	-	-	-	-	DUF1831
IGHDCBEA_01716	1046629.Ssal_00613	9.05e-152	427.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli	91061|Bacilli	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
IGHDCBEA_01717	1046629.Ssal_00612	5.88e-163	456.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli	91061|Bacilli	T	peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
IGHDCBEA_01718	322159.STER_1430	2.67e-153	431.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
IGHDCBEA_01719	1046629.Ssal_00610	0.0	1025.0	COG3754@1|root,COG3754@2|Bacteria	2|Bacteria	M	Rhamnan synthesis protein F	rgpF	-	-	ko:K07272	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	RgpF
IGHDCBEA_01720	904306.HMPREF9192_0927	1.07e-284	778.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli	91061|Bacilli	P	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system	rgpD	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
IGHDCBEA_01721	1046629.Ssal_00608	1.09e-181	506.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes	1239|Firmicutes	GM	Transport permease protein	-	-	-	ko:K01992,ko:K09690,ko:K09692	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC2_membrane
IGHDCBEA_01722	1046629.Ssal_00607	2.12e-226	623.0	COG0463@1|root,COG0463@2|Bacteria,1V7IQ@1239|Firmicutes,4HK7R@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase, group 2 family protein	rgpB	-	-	ko:K12997	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
IGHDCBEA_01723	904306.HMPREF9192_0924	2.24e-286	781.0	COG0438@1|root,COG0438@2|Bacteria,1V7K7@1239|Firmicutes,4HA9A@91061|Bacilli	91061|Bacilli	M	Domain of unknown function (DUF1972)	rgpA	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	DUF1972,Glycos_transf_1
IGHDCBEA_01724	1046629.Ssal_00604	0.0	907.0	2AJ90@1|root,319TX@2|Bacteria,1VFA5@1239|Firmicutes,4HS62@91061|Bacilli	91061|Bacilli	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
IGHDCBEA_01725	1046629.Ssal_00603	1.4e-299	817.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
IGHDCBEA_01726	1046629.Ssal_00602	8.46e-283	774.0	COG4713@1|root,COG4713@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
IGHDCBEA_01727	1046629.Ssal_00601	0.0	1914.0	COG0438@1|root,COG1215@1|root,COG3754@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,COG3754@2|Bacteria,1UJI4@1239|Firmicutes,4HNC8@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IGHDCBEA_01728	1046629.Ssal_00600	4.03e-197	545.0	COG1216@1|root,COG1216@2|Bacteria,1UI19@1239|Firmicutes	1239|Firmicutes	S	Glycosyltransferase group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IGHDCBEA_01729	1046629.Ssal_00599	1.83e-62	192.0	2EVMS@1|root,33P1S@2|Bacteria,1VPQZ@1239|Firmicutes	1239|Firmicutes	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
IGHDCBEA_01730	322159.STER_1440	2.46e-162	455.0	COG1215@1|root,COG1215@2|Bacteria,1UHQZ@1239|Firmicutes,4IS6R@91061|Bacilli	91061|Bacilli	M	group 2 family protein	arnC	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
IGHDCBEA_01731	1046629.Ssal_00597	1.33e-228	630.0	COG0463@1|root,COG0463@2|Bacteria,1V8FV@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IGHDCBEA_01732	1046629.Ssal_00596	3.32e-284	779.0	COG2244@1|root,COG2244@2|Bacteria,1V1RP@1239|Firmicutes,4IR8D@91061|Bacilli	91061|Bacilli	S	membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
IGHDCBEA_01733	1046629.Ssal_00595	5.74e-205	566.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
IGHDCBEA_01734	1046629.Ssal_00594	0.0	900.0	2EPWD@1|root,33HGX@2|Bacteria,1VQBK@1239|Firmicutes,4HUQ1@91061|Bacilli	91061|Bacilli	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
IGHDCBEA_01735	1046629.Ssal_00592	9.27e-219	603.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli	91061|Bacilli	M	COG0463, glycosyltransferases involved in cell wall biogenesis	yfdH	-	-	ko:K12999,ko:K20534	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
IGHDCBEA_01736	1046629.Ssal_00591	1.01e-73	221.0	COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli	91061|Bacilli	K	metal-sulfur cluster biosynthetic enzyme	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
IGHDCBEA_01737	1046629.Ssal_00589	2.49e-256	704.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
IGHDCBEA_01738	1046629.Ssal_00588	0.0	1176.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli	91061|Bacilli	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
IGHDCBEA_01739	1046629.Ssal_00587	2.94e-75	226.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli	91061|Bacilli	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
IGHDCBEA_01740	1046629.Ssal_00586	8.61e-28	101.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
IGHDCBEA_01741	1046629.Ssal_00585	2.45e-176	493.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli	91061|Bacilli	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IGHDCBEA_01742	1046629.Ssal_00584	6.77e-270	738.0	COG0436@1|root,COG0436@2|Bacteria,1TQPD@1239|Firmicutes,4HE7P@91061|Bacilli	91061|Bacilli	E	Aminotransferase	arcT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
IGHDCBEA_01743	1046629.Ssal_00583	6.55e-179	499.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes	1239|Firmicutes	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IGHDCBEA_01744	1046629.Ssal_00582	4.43e-182	508.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HJ2R@91061|Bacilli	91061|Bacilli	ET	ABC transporter	XK27_04395	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
IGHDCBEA_01745	1046629.Ssal_00581	1.24e-108	312.0	COG1051@1|root,COG1051@2|Bacteria,1V3MM@1239|Firmicutes	1239|Firmicutes	F	Nudix family	XK27_04400	-	3.6.1.55	ko:K03574,ko:K12944	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IGHDCBEA_01747	435842.HMPREF0848_01113	2.47e-24	101.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli	91061|Bacilli	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
IGHDCBEA_01748	999425.HMPREF9186_00382	2.73e-147	414.0	COG2249@1|root,COG2249@2|Bacteria,1VC9F@1239|Firmicutes,4HKPT@91061|Bacilli	91061|Bacilli	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
IGHDCBEA_01749	1046629.Ssal_00578	4.77e-116	332.0	COG0454@1|root,COG0456@2|Bacteria,1VEEJ@1239|Firmicutes,4HP6M@91061|Bacilli	91061|Bacilli	K	Gnat family	yfbM	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IGHDCBEA_01750	1046629.Ssal_00577	0.0	1282.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli	91061|Bacilli	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
IGHDCBEA_01752	1046629.Ssal_00575	9.21e-216	596.0	COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4IQWI@91061|Bacilli	91061|Bacilli	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IGHDCBEA_01753	1046629.Ssal_00574	0.0	1385.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli	91061|Bacilli	P	ABC-type amino acid transport signal transduction systems periplasmic component domain	glnP	-	-	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.2	-	-	BPD_transp_1,SBP_bac_3
IGHDCBEA_01754	1046629.Ssal_00573	3.54e-176	491.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IGHDCBEA_01755	1321372.AQQB01000060_gene15	5.23e-25	94.4	29R2M@1|root,30C3R@2|Bacteria,1U94Q@1239|Firmicutes,4IJ5T@91061|Bacilli,1WTRS@1307|Streptococcus suis	91061|Bacilli	-	-	XK27_00735	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01756	904306.HMPREF9192_0893	3.8e-315	858.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli	91061|Bacilli	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
IGHDCBEA_01757	388919.SSA_0806	9.86e-10	54.3	29RNI@1|root,30CRU@2|Bacteria,1UA9S@1239|Firmicutes,4IKMB@91061|Bacilli,1WS04@1305|Streptococcus sanguinis	91061|Bacilli	S	Protein of unknown function (DUF4044)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4044
IGHDCBEA_01758	1046629.Ssal_00568	8.31e-169	472.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IGHDCBEA_01759	883156.HMPREF9282_01673	4.89e-09	65.5	COG1397@1|root,COG1397@2|Bacteria,1V7HC@1239|Firmicutes,4H7XK@909932|Negativicutes	909932|Negativicutes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01760	264199.stu1516	8.12e-82	243.0	COG2050@1|root,COG2050@2|Bacteria,1VN0K@1239|Firmicutes,4HM66@91061|Bacilli	91061|Bacilli	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
IGHDCBEA_01761	1046629.Ssal_00565	1.73e-81	241.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K06889,ko:K07397,ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	Hydrolase_4,OsmC,YcaO
IGHDCBEA_01763	1046629.Ssal_00562	2.99e-193	538.0	COG0697@1|root,COG0697@2|Bacteria,1TYSF@1239|Firmicutes	1239|Firmicutes	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IGHDCBEA_01765	1046629.Ssal_02154	0.0	1251.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli	91061|Bacilli	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
IGHDCBEA_01766	1046629.Ssal_02155	3.15e-126	359.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli	91061|Bacilli	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
IGHDCBEA_01767	1046629.Ssal_02156	3.61e-305	832.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
IGHDCBEA_01768	1046629.Ssal_02157	2.34e-301	823.0	COG2367@1|root,COG2367@2|Bacteria,1VGXR@1239|Firmicutes,4IPWW@91061|Bacilli	91061|Bacilli	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase2,SH3_8
IGHDCBEA_01769	388919.SSA_0011	1.36e-05	43.9	29RP0@1|root,30CSA@2|Bacteria,1UAAD@1239|Firmicutes,4IKMY@91061|Bacilli,1WS12@1305|Streptococcus sanguinis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01770	322159.STER_0009	3.9e-79	235.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli	91061|Bacilli	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
IGHDCBEA_01771	1046629.Ssal_02160	1.87e-53	168.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli	91061|Bacilli	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	yabO	-	-	-	-	-	-	-	-	-	-	-	S4
IGHDCBEA_01772	1046629.Ssal_02161	0.0	2237.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli	91061|Bacilli	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
IGHDCBEA_01773	1046629.Ssal_02162	2.11e-133	378.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
IGHDCBEA_01774	1046629.Ssal_02163	7.47e-259	710.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
IGHDCBEA_01775	1046629.Ssal_02164	1.4e-40	133.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	yyzM	-	-	-	-	-	-	-	-	-	-	-	DUF951
IGHDCBEA_01776	904306.HMPREF9192_1861	3.94e-253	696.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli	91061|Bacilli	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
IGHDCBEA_01777	1046629.Ssal_00001	0.0	888.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
IGHDCBEA_01778	1046629.Ssal_00002	9.67e-174	485.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
IGHDCBEA_01779	1046629.Ssal_00003	1.01e-274	754.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli	91061|Bacilli	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'	htrA	GO:0008150,GO:0009266,GO:0009628,GO:0050896	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
IGHDCBEA_01780	1046629.Ssal_00004	2.89e-105	304.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli	91061|Bacilli	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
IGHDCBEA_01781	1046629.Ssal_00005	4.48e-153	431.0	COG3619@1|root,COG3619@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1275)	yoaK	-	-	-	-	-	-	-	-	-	-	-	DUF1275
IGHDCBEA_01785	1046629.Ssal_00006	0.0	1646.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli	91061|Bacilli	S	Bacterial membrane protein YfhO	XK27_10405	-	-	-	-	-	-	-	-	-	-	-	YfhO
IGHDCBEA_01786	1046629.Ssal_00007	0.0	1053.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
IGHDCBEA_01787	1046629.Ssal_00008	3.96e-195	542.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli	91061|Bacilli	S	membrane	XK27_10395	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IGHDCBEA_01788	1046629.Ssal_00009	9.58e-244	669.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli	91061|Bacilli	J	Tryptophanyl-tRNA synthetase	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
IGHDCBEA_01789	1046629.Ssal_00010	0.0	948.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli	91061|Bacilli	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
IGHDCBEA_01790	1046629.Ssal_00011	2.62e-261	716.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
IGHDCBEA_01791	1046629.Ssal_00012	1.07e-77	232.0	COG2501@1|root,COG2501@2|Bacteria,1VKF4@1239|Firmicutes,4HRX5@91061|Bacilli	91061|Bacilli	S	S4 domain protein YaaA	yaaA	-	-	-	-	-	-	-	-	-	-	-	S4_2
IGHDCBEA_01792	1046629.Ssal_00013	3.18e-301	821.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli	91061|Bacilli	S	Peptidase M16	albE	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
IGHDCBEA_01793	1046629.Ssal_00014	1.54e-308	840.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli	91061|Bacilli	S	Peptidase M16	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
IGHDCBEA_01794	1046629.Ssal_00015	4.45e-171	480.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25,HTH_3
IGHDCBEA_01795	1046629.Ssal_00016	2.68e-118	339.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli	91061|Bacilli	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06365	CDP-OH_P_transf
IGHDCBEA_01796	1046629.Ssal_00017	1.57e-194	540.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli	91061|Bacilli	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IGHDCBEA_01797	1046629.Ssal_00018	2.71e-197	547.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli	91061|Bacilli	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656	-	ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IGHDCBEA_01798	264199.stu2007	1.25e-169	476.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli	91061|Bacilli	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
IGHDCBEA_01799	435842.HMPREF0848_01703	1.25e-108	315.0	COG1388@1|root,COG1388@2|Bacteria,1VA10@1239|Firmicutes,4HMUH@91061|Bacilli	91061|Bacilli	M	LysM domain protein	lytE	-	-	-	-	-	-	-	-	-	-	-	LysM
IGHDCBEA_01800	1046629.Ssal_00021	1.18e-126	364.0	COG0741@1|root,COG0741@2|Bacteria,1VGPA@1239|Firmicutes,4HP1I@91061|Bacilli	91061|Bacilli	M	Immunodominant staphylococcal antigen A	isaA	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5,LysM,SLT,Transglycosylas
IGHDCBEA_01801	1046629.Ssal_00022	0.0	1077.0	COG4485@1|root,COG4485@2|Bacteria,1V0XZ@1239|Firmicutes,4HEBN@91061|Bacilli	91061|Bacilli	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01802	1046629.Ssal_00023	3.82e-278	759.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
IGHDCBEA_01803	467705.SGO_0023	6.35e-131	373.0	COG2095@1|root,COG2095@2|Bacteria,1V81W@1239|Firmicutes,4HIUV@91061|Bacilli	91061|Bacilli	U	UPF0056 membrane protein	yvbG	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
IGHDCBEA_01804	1046629.Ssal_00025	0.0	1239.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli	91061|Bacilli	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
IGHDCBEA_01805	904306.HMPREF9192_1894	0.0	1218.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli	91061|Bacilli	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
IGHDCBEA_01806	1046629.Ssal_00027	1.77e-98	286.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli	91061|Bacilli	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
IGHDCBEA_01807	1046629.Ssal_00028	1.35e-314	858.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaC	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
IGHDCBEA_01808	1046629.Ssal_00029	6.16e-63	192.0	COG4466@1|root,COG4466@2|Bacteria,1VPZY@1239|Firmicutes,4HSFF@91061|Bacilli	91061|Bacilli	S	Biofilm formation stimulator VEG	WQ51_01655	-	-	-	-	-	-	-	-	-	-	-	VEG
IGHDCBEA_01809	1046629.Ssal_00030	1.25e-141	400.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
IGHDCBEA_01810	1260356.D920_01191	5.32e-13	63.9	2914P@1|root,2ZNS1@2|Bacteria,1W3FT@1239|Firmicutes,4I23Q@91061|Bacilli,4B40K@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01811	1046629.Ssal_00032	6.55e-72	217.0	COG3759@1|root,COG3759@2|Bacteria,1VAEU@1239|Firmicutes	1239|Firmicutes	M	Membrane	XK27_04840	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
IGHDCBEA_01812	1046629.Ssal_00033	1.69e-125	357.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	XK27_06935	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
IGHDCBEA_01813	904306.HMPREF9192_1903	4.31e-261	750.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli	91061|Bacilli	V	domain protein	XK27_06930	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
IGHDCBEA_01814	1046629.Ssal_00035	1.46e-144	414.0	COG3595@1|root,COG3595@2|Bacteria,1VGGF@1239|Firmicutes	1239|Firmicutes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
IGHDCBEA_01815	904306.HMPREF9192_1905	2.33e-96	285.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,4HSRQ@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1700)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
IGHDCBEA_01816	1046629.Ssal_00037	4.5e-71	214.0	COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,4IR4R@91061|Bacilli	91061|Bacilli	K	transcriptional regulator, PadR family	XK27_06915	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
IGHDCBEA_01817	1046629.Ssal_00038	7.02e-152	426.0	COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli	91061|Bacilli	L	hydrolase	XK27_06885	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IGHDCBEA_01822	1046629.Ssal_00040	0.0	985.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,4HEX0@91061|Bacilli	91061|Bacilli	K	transcriptional regulator containing an HTH domain and an	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,Penicillinase_R
IGHDCBEA_01823	1449338.JQLU01000004_gene433	2.94e-81	254.0	2DE1M@1|root,2ZK4S@2|Bacteria,1W5TM@1239|Firmicutes,4I0Y4@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01826	1000588.HMPREF9965_1537	4.6e-82	244.0	2DKDH@1|root,3097S@2|Bacteria,1U4K6@1239|Firmicutes,4IEBY@91061|Bacilli,2TQ0T@28037|Streptococcus mitis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01827	1046629.Ssal_00046	1.44e-255	699.0	COG2946@1|root,COG2946@2|Bacteria,1V0X4@1239|Firmicutes,4HF5X@91061|Bacilli	91061|Bacilli	L	Replication initiation factor	-	-	-	-	-	-	-	-	-	-	-	-	Rep_trans
IGHDCBEA_01829	1046629.Ssal_00048	0.0	957.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IGHDCBEA_01830	1046629.Ssal_00049	2.9e-293	803.0	2C4MM@1|root,340I6@2|Bacteria,1VX2D@1239|Firmicutes,4HWVM@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
IGHDCBEA_01831	1046629.Ssal_00050	2.37e-165	463.0	COG1136@1|root,COG1136@2|Bacteria,1VUXT@1239|Firmicutes,4HVWM@91061|Bacilli	91061|Bacilli	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IGHDCBEA_01832	1046629.Ssal_00051	1.22e-26	97.4	COG0267@1|root,COG0267@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
IGHDCBEA_01833	1046629.Ssal_00052	8.74e-36	121.0	COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
IGHDCBEA_01834	1046629.Ssal_00053	1.5e-278	760.0	COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli	91061|Bacilli	E	Methionine synthase	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
IGHDCBEA_01835	1046629.Ssal_00054	1.29e-312	853.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli	91061|Bacilli	G	pts system	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
IGHDCBEA_01836	1046629.Ssal_00055	8.85e-304	828.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli	91061|Bacilli	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
IGHDCBEA_01838	1046629.Ssal_00058	0.0	1137.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
IGHDCBEA_01839	1046629.Ssal_00059	2.53e-214	593.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli	91061|Bacilli	S	cog cog1284	XK27_01785	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IGHDCBEA_01840	1046629.Ssal_00060	4.12e-159	446.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0246 family	XK27_08125	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
IGHDCBEA_01841	1046629.Ssal_00061	8.87e-150	420.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli	91061|Bacilli	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
IGHDCBEA_01842	1046629.Ssal_00062	9.97e-114	326.0	COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,4HG6C@91061|Bacilli	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
IGHDCBEA_01843	435842.HMPREF0848_01736	7.68e-20	80.1	2DEKJ@1|root,2ZNBP@2|Bacteria,1TXD1@1239|Firmicutes,4HZYT@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01844	1046629.Ssal_00064	0.0	1491.0	COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli	91061|Bacilli	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
IGHDCBEA_01845	1046629.Ssal_00065	0.0	1040.0	2F2IJ@1|root,33VFI@2|Bacteria,1V9D8@1239|Firmicutes,4HS77@91061|Bacilli	91061|Bacilli	S	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01846	1046629.Ssal_00066	1.34e-62	192.0	COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0473 family	yrzB	-	-	-	-	-	-	-	-	-	-	-	DUF1292
IGHDCBEA_01847	435842.HMPREF0848_01740	1.39e-91	268.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
IGHDCBEA_01848	1046629.Ssal_00068	9.75e-59	181.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
IGHDCBEA_01849	1046629.Ssal_00069	1.73e-36	123.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
IGHDCBEA_01850	1046629.Ssal_00070	5.94e-300	818.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli	91061|Bacilli	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
IGHDCBEA_01852	264199.stu1955	5.75e-235	650.0	COG0582@1|root,COG0582@2|Bacteria,1VTS1@1239|Firmicutes,4HU1E@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IGHDCBEA_01853	585204.SMSK597_1426	2.78e-26	97.4	28YJG@1|root,2ZKDA@2|Bacteria,1W5B5@1239|Firmicutes,4I02K@91061|Bacilli,2TQ3X@28037|Streptococcus mitis	91061|Bacilli	S	Domain of unknown function (DUF3173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3173
IGHDCBEA_01854	1403946.Q615_SPAC00126G0051	1.55e-184	518.0	COG2946@1|root,COG2946@2|Bacteria,1VMP1@1239|Firmicutes,4HSQH@91061|Bacilli,42EH0@671232|Streptococcus anginosus group	91061|Bacilli	L	Replication initiation factor	-	-	-	-	-	-	-	-	-	-	-	-	Rep_trans
IGHDCBEA_01855	889204.HMPREF9423_1756	8.59e-96	281.0	COG1476@1|root,COG1476@2|Bacteria,1TWG7@1239|Firmicutes,4I59F@91061|Bacilli,43G5U@68892|Streptococcus infantis	91061|Bacilli	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01857	626523.GCWU000342_02015	9.32e-156	440.0	COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,24HPX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
IGHDCBEA_01858	626523.GCWU000342_02014	2.03e-172	486.0	COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,25B0Q@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
IGHDCBEA_01859	626523.GCWU000342_02013	5.59e-37	124.0	2E3AZ@1|root,32YAF@2|Bacteria,1VF37@1239|Firmicutes,24R3T@186801|Clostridia	186801|Clostridia	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
IGHDCBEA_01861	1046629.Ssal_00076	4.54e-118	337.0	COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,4HH8A@91061|Bacilli	91061|Bacilli	F	topology modulation protein	flaR	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01862	1046629.Ssal_00077	6.38e-315	857.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli	91061|Bacilli	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
IGHDCBEA_01863	1046629.Ssal_00078	5.19e-103	297.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli	91061|Bacilli	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
IGHDCBEA_01864	1046629.Ssal_00079	3.45e-47	155.0	COG4642@1|root,COG4642@2|Bacteria,1TRNW@1239|Firmicutes	1239|Firmicutes	S	MORN repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN
IGHDCBEA_01865	1046629.Ssal_00080	0.0	1149.0	COG1835@1|root,COG1835@2|Bacteria,1U6DU@1239|Firmicutes,4H9XT@91061|Bacilli	91061|Bacilli	I	Acyltransferase	XK27_09800	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IGHDCBEA_01870	1046629.Ssal_01730	0.0	1707.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli	91061|Bacilli	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
IGHDCBEA_01871	435842.HMPREF0848_00077	1.09e-110	318.0	COG4894@1|root,COG4894@2|Bacteria,1VBT3@1239|Firmicutes,4HH8W@91061|Bacilli	91061|Bacilli	S	LURP-one-related	XK27_03390	-	-	-	-	-	-	-	-	-	-	-	LOR
IGHDCBEA_01872	1046629.Ssal_01733	3.93e-238	659.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	prsA	-	3.1.3.16,5.2.1.8	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
IGHDCBEA_01873	1046629.Ssal_01734	5.91e-155	436.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli	91061|Bacilli	S	O-Methyltransferase	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
IGHDCBEA_01874	1046629.Ssal_01735	2.91e-276	757.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli	91061|Bacilli	P	COG0477 Permeases of the major facilitator superfamily	oxlT	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
IGHDCBEA_01875	1046629.Ssal_01736	0.0	1200.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli	91061|Bacilli	E	oligoendopeptidase F	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
IGHDCBEA_01876	1046629.Ssal_01737	8.04e-230	632.0	COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli	91061|Bacilli	S	Competence protein	coiA	-	-	ko:K06198	-	-	-	-	ko00000	-	-	-	CoiA
IGHDCBEA_01877	1046629.Ssal_01738	1.34e-43	145.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
IGHDCBEA_01878	1046629.Ssal_01739	6.21e-31	110.0	COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes	1239|Firmicutes	L	Integrase core domain protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_28,rve,rve_2
IGHDCBEA_01879	1008453.HMPREF9957_1401	1.88e-28	110.0	COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,4HAJS@91061|Bacilli,2TP00@28037|Streptococcus mitis	91061|Bacilli	L	overlaps another CDS with the same product name	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
IGHDCBEA_01880	1046629.Ssal_01740	2.42e-205	567.0	COG3942@1|root,COG3942@2|Bacteria,1VUNU@1239|Firmicutes,4HVY0@91061|Bacilli	91061|Bacilli	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,SH3_5
IGHDCBEA_01881	1046629.Ssal_01741	0.0	1159.0	2DGEP@1|root,2ZVNT@2|Bacteria	2|Bacteria	S	Glucan-binding protein C	-	-	-	-	-	-	-	-	-	-	-	-	GbpC,Gram_pos_anchor
IGHDCBEA_01882	435842.HMPREF0848_00071	8.29e-135	387.0	COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes	1239|Firmicutes	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IGHDCBEA_01883	1046629.Ssal_01743	4.31e-215	594.0	COG0583@1|root,COG0583@2|Bacteria,1V53I@1239|Firmicutes,4HIEU@91061|Bacilli	91061|Bacilli	K	transcriptional regulator (lysR family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IGHDCBEA_01884	1046629.Ssal_01744	6.98e-205	566.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli	91061|Bacilli	S	reductase	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
IGHDCBEA_01885	1046629.Ssal_01745	0.0	1328.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
IGHDCBEA_01889	322159.STER_0480	6.93e-239	658.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli	91061|Bacilli	T	phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
IGHDCBEA_01890	1046629.Ssal_01753	2.07e-209	589.0	COG1388@1|root,COG1388@2|Bacteria,1V61Q@1239|Firmicutes,4HHT0@91061|Bacilli	91061|Bacilli	M	LysM domain protein	sip	-	-	-	-	-	-	-	-	-	-	-	LysM
IGHDCBEA_01891	904306.HMPREF9192_0353	2.72e-46	148.0	COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0346 family	yozE	-	-	-	-	-	-	-	-	-	-	-	YozE_SAM_like
IGHDCBEA_01892	1046629.Ssal_01755	2.34e-205	568.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	yitL	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
IGHDCBEA_01893	1046629.Ssal_01756	1.94e-118	340.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
IGHDCBEA_01894	1046629.Ssal_01757	2.78e-168	471.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli	91061|Bacilli	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
IGHDCBEA_01895	1046629.Ssal_01758	1.2e-280	768.0	COG0642@1|root,COG0642@2|Bacteria,1UHQH@1239|Firmicutes,4HAHG@91061|Bacilli	91061|Bacilli	T	Histidine kinase	sptS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
IGHDCBEA_01896	1046629.Ssal_01760	7.4e-154	432.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HG2E@91061|Bacilli	91061|Bacilli	T	response regulator	dltr	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IGHDCBEA_01897	1046629.Ssal_01761	2.51e-143	404.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HTR5@91061|Bacilli	91061|Bacilli	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
IGHDCBEA_01898	1046629.Ssal_01762	9.47e-146	410.0	COG0454@1|root,COG0456@2|Bacteria,1VF01@1239|Firmicutes,4HPKN@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
IGHDCBEA_01899	1046629.Ssal_01763	0.0	1117.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	lmrA2	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_01900	1046629.Ssal_01764	0.0	1092.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	lmrA1	-	-	ko:K02021,ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
IGHDCBEA_01901	264199.stu0432	9.59e-96	279.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
IGHDCBEA_01902	1046629.Ssal_01766	7.84e-92	268.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,4HGYC@91061|Bacilli	91061|Bacilli	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def_1	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IGHDCBEA_01903	1046629.Ssal_01767	0.0	981.0	COG5617@1|root,COG5617@2|Bacteria,1VS0Z@1239|Firmicutes,4HJQE@91061|Bacilli	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01904	1046629.Ssal_01768	0.0	880.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
IGHDCBEA_01905	1046629.Ssal_01769	4.13e-258	708.0	COG1057@1|root,COG3172@1|root,COG1057@2|Bacteria,COG3172@2|Bacteria,1TQ29@1239|Firmicutes,4HBZT@91061|Bacilli	91061|Bacilli	H	adenylyltransferase	nadR	-	-	-	-	-	-	-	-	-	-	-	AAA_28,CTP_transf_like
IGHDCBEA_01906	904306.HMPREF9192_0338	2.97e-167	469.0	COG1051@1|root,COG1051@2|Bacteria,1TST7@1239|Firmicutes,4HEFP@91061|Bacilli	91061|Bacilli	F	AdP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IGHDCBEA_01907	764298.STRMA_0561	7.78e-31	116.0	COG3247@1|root,COG3247@2|Bacteria,1VK2X@1239|Firmicutes	1239|Firmicutes	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
IGHDCBEA_01908	1046629.Ssal_01772	0.0	1190.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IGHDCBEA_01909	1046629.Ssal_01773	2.34e-280	767.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli	91061|Bacilli	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
IGHDCBEA_01910	1046629.Ssal_01774	1.49e-177	495.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli	91061|Bacilli	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU22490	DapB_C,DapB_N
IGHDCBEA_01911	1046629.Ssal_01775	6.12e-194	538.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HVKJ@91061|Bacilli	91061|Bacilli	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
IGHDCBEA_01912	1046629.Ssal_01776	2.63e-82	243.0	COG4835@1|root,COG4835@2|Bacteria,1VHA6@1239|Firmicutes,4HPTC@91061|Bacilli	91061|Bacilli	S	cog cog4835	WQ51_03320	-	-	-	-	-	-	-	-	-	-	-	DUF1149
IGHDCBEA_01913	1046629.Ssal_01777	3.57e-173	482.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	ydaF_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
IGHDCBEA_01914	1046629.Ssal_01778	1.55e-61	189.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
IGHDCBEA_01915	264199.stu0417	1.99e-64	198.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
IGHDCBEA_01916	1046629.Ssal_01780	6.12e-123	350.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_7
IGHDCBEA_01917	1046629.Ssal_01781	0.0	884.0	COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes	1239|Firmicutes	M	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1	gtf2	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01918	1046629.Ssal_01782	0.0	1001.0	COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli	91061|Bacilli	M	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon	gtf1	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
IGHDCBEA_01919	435842.HMPREF0848_00031	2.63e-284	778.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli	91061|Bacilli	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
IGHDCBEA_01920	1046629.Ssal_01786	3.49e-269	737.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli	91061|Bacilli	E	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	iscS2	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IGHDCBEA_01921	1005705.HMPREF9967_0802	1.4e-07	55.5	2DIXV@1|root,304C8@2|Bacteria,1TWH5@1239|Firmicutes,4I5AH@91061|Bacilli,43G9W@68892|Streptococcus infantis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01922	1046629.Ssal_01788	3.49e-288	788.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli	91061|Bacilli	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08370	Mur_ligase_C,Mur_ligase_M
IGHDCBEA_01923	1046629.Ssal_01790	0.0	898.0	COG1249@1|root,COG1249@2|Bacteria,1TQFH@1239|Firmicutes,4HCT8@91061|Bacilli	91061|Bacilli	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
IGHDCBEA_01924	1046629.Ssal_01791	0.0	1199.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli	91061|Bacilli	G	phosphotransferase system	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
IGHDCBEA_01925	1046629.Ssal_01792	1.12e-212	588.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli	91061|Bacilli	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iYO844.BSU14390	PfkB
IGHDCBEA_01926	1046629.Ssal_01793	5.33e-163	457.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli	91061|Bacilli	K	transcriptional	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
IGHDCBEA_01927	904306.HMPREF9192_0315	6.36e-290	803.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli	91061|Bacilli	D	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
IGHDCBEA_01928	1046629.Ssal_01795	6.58e-116	331.0	COG1854@1|root,COG1854@2|Bacteria,1V1V3@1239|Firmicutes,4HFR0@91061|Bacilli	91061|Bacilli	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
IGHDCBEA_01929	1046629.Ssal_01796	3.8e-176	491.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
IGHDCBEA_01930	1046629.Ssal_01797	1.99e-203	563.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli	91061|Bacilli	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
IGHDCBEA_01931	1046629.Ssal_01798	0.0	887.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
IGHDCBEA_01932	1046629.Ssal_01800	1.19e-93	273.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli	91061|Bacilli	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
IGHDCBEA_01933	1046629.Ssal_01801	1.85e-83	249.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli	91061|Bacilli	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
IGHDCBEA_01934	1046629.Ssal_01802	3.69e-297	810.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
IGHDCBEA_01935	904306.HMPREF9192_0291	5.57e-163	457.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
IGHDCBEA_01936	1046629.Ssal_01804	1.06e-207	575.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli	91061|Bacilli	I	Malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Acyl_transf_1
IGHDCBEA_01937	1046629.Ssal_01805	3.23e-221	611.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli	91061|Bacilli	S	2-Nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
IGHDCBEA_01938	1046629.Ssal_01806	2.12e-40	134.0	COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli	91061|Bacilli	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
IGHDCBEA_01939	1046629.Ssal_01807	5.53e-217	600.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
IGHDCBEA_01940	1046629.Ssal_01808	2.67e-96	280.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4HIMR@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator, MarR family	XK27_02735	-	-	-	-	-	-	-	-	-	-	-	MarR
IGHDCBEA_01941	1046629.Ssal_01809	9.63e-181	504.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	phaB	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576	5.3.3.14,5.3.3.18	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	-	R07639,R09837,R09839	RC00004,RC00326,RC01078,RC02689,RC03003	ko00000,ko00001,ko01000,ko01004	-	-	-	ECH_1
IGHDCBEA_01942	1046629.Ssal_01810	3.43e-148	417.0	COG0637@1|root,COG0637@2|Bacteria,1VA1U@1239|Firmicutes,4HMKX@91061|Bacilli	91061|Bacilli	S	HAD hydrolase, family IA, variant 3	yhfA	-	-	-	-	-	-	-	-	-	-	-	HAD_2
IGHDCBEA_01943	1046629.Ssal_01811	0.0	890.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli	91061|Bacilli	E	Belongs to the aspartokinase family	lysC	GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU03790	AA_kinase,ACT,ACT_7
IGHDCBEA_01944	1046629.Ssal_01812	1.53e-244	671.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,4HAEC@91061|Bacilli	91061|Bacilli	E	aspartate--ammonia ligase	asnA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
IGHDCBEA_01945	1046629.Ssal_01813	7.59e-314	855.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA_1	-	2.1.1.190,2.1.1.35	ko:K00557,ko:K03215	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	TRAM,tRNA_U5-meth_tr
IGHDCBEA_01946	1046629.Ssal_01814	1.14e-178	498.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HKE3@91061|Bacilli	91061|Bacilli	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
IGHDCBEA_01947	1046629.Ssal_01815	1.99e-132	374.0	COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli	91061|Bacilli	J	Belongs to the UPF0374 family	ygaC	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
IGHDCBEA_01952	999425.HMPREF9186_01381	2.3e-256	704.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HE6X@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_5,Phage_integrase
IGHDCBEA_01953	1095726.HMPREF1116_1621	1.45e-38	128.0	28YJG@1|root,2ZKDA@2|Bacteria,1W5B5@1239|Firmicutes,4I02K@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3173
IGHDCBEA_01954	1114965.Spaf_0244	1.97e-88	259.0	2DAFF@1|root,32TVB@2|Bacteria,1VD11@1239|Firmicutes,4HMK7@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01955	435842.HMPREF0848_01871	1.04e-290	793.0	COG2946@1|root,COG2946@2|Bacteria,1UYFS@1239|Firmicutes,4HPK6@91061|Bacilli	91061|Bacilli	L	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	Rep_trans
IGHDCBEA_01956	997830.HMPREF1124_0514	2.11e-97	284.0	2DIZ4@1|root,304E2@2|Bacteria,1TWJP@1239|Firmicutes,4I5D7@91061|Bacilli,43GFM@68892|Streptococcus infantis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01957	1114965.Spaf_0247	1.11e-100	292.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli	91061|Bacilli	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IGHDCBEA_01959	888049.HMPREF8578_0301	1.06e-191	532.0	28IWY@1|root,2Z8V1@2|Bacteria,1VA13@1239|Firmicutes,4HZ1G@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01961	1046629.Ssal_02107	0.0	2887.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli	91061|Bacilli	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
IGHDCBEA_01962	1046629.Ssal_02106	3.57e-301	821.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli	91061|Bacilli	E	COG2309 Leucyl aminopeptidase (aminopeptidase T)	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
IGHDCBEA_01963	904306.HMPREF9192_0535	1.4e-48	154.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	XK27_02060	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
IGHDCBEA_01964	1046629.Ssal_02104	1.89e-95	278.0	COG1846@1|root,COG1846@2|Bacteria,1VB3Q@1239|Firmicutes,4HP7J@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator, marr family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
IGHDCBEA_01965	1046629.Ssal_02103	3.26e-124	354.0	COG0431@1|root,COG0431@2|Bacteria,1VAI8@1239|Firmicutes	1239|Firmicutes	S	reductase	XK27_03570	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
IGHDCBEA_01967	1046629.Ssal_02102	0.0	989.0	COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli	91061|Bacilli	O	alkyl hydroperoxide reductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
IGHDCBEA_01968	1046629.Ssal_02101	1.73e-136	386.0	COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli	91061|Bacilli	O	alkyl hydroperoxide reductase	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
IGHDCBEA_01969	1046629.Ssal_02100	2.48e-176	492.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
IGHDCBEA_01970	1046629.Ssal_02098	1.23e-233	644.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli	91061|Bacilli	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
IGHDCBEA_01971	1046629.Ssal_02096	3.41e-107	309.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,4HPN6@91061|Bacilli	91061|Bacilli	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
IGHDCBEA_01972	1046629.Ssal_02095	5.72e-99	288.0	COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli	91061|Bacilli	K	Belongs to the CtsR family	ctsR	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03708	-	-	-	-	ko00000,ko03000	-	-	-	CtsR
IGHDCBEA_01973	904306.HMPREF9192_0525	0.0	1548.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
IGHDCBEA_01974	1046629.Ssal_02093	2.47e-298	815.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli	91061|Bacilli	M	Belongs to the peptidase S11 family	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
IGHDCBEA_01975	1046629.Ssal_02092	5.36e-292	798.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli	91061|Bacilli	M	Belongs to the peptidase S11 family	dacA	GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
IGHDCBEA_01976	1046629.Ssal_02091	0.0	1366.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
IGHDCBEA_01977	1046629.Ssal_02090	3.4e-179	499.0	2F67I@1|root,33YRI@2|Bacteria,1VY65@1239|Firmicutes,4HXHY@91061|Bacilli	91061|Bacilli	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
IGHDCBEA_01978	435842.HMPREF0848_01892	6.37e-144	406.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli	91061|Bacilli	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
IGHDCBEA_01980	1046629.Ssal_02087	0.0	892.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
IGHDCBEA_01981	1046629.Ssal_02085	1.22e-89	263.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli	91061|Bacilli	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
IGHDCBEA_01983	1046629.Ssal_02082	1.75e-172	481.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
IGHDCBEA_01984	1046629.Ssal_02081	2e-120	343.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli	91061|Bacilli	S	RNA-binding protein containing a PIN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
IGHDCBEA_01985	1046629.Ssal_02080	3.03e-197	547.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli	91061|Bacilli	S	DegV family	yitS	-	-	-	-	-	-	-	-	-	-	-	DegV
IGHDCBEA_01987	1046629.Ssal_02078	1.21e-40	134.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli	91061|Bacilli	K	Transcriptional	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
IGHDCBEA_01988	1046629.Ssal_02077	7.02e-103	297.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli	91061|Bacilli	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
IGHDCBEA_01989	435842.HMPREF0848_01903	2.12e-84	249.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli	91061|Bacilli	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
IGHDCBEA_01990	862967.SIR_1575	4.35e-282	772.0	COG0582@1|root,COG0582@2|Bacteria,1TRCD@1239|Firmicutes,4HDUS@91061|Bacilli,42DYV@671232|Streptococcus anginosus group	91061|Bacilli	L	Phage integrase family	int2	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IGHDCBEA_01991	1123302.KB904164_gene698	3.22e-45	147.0	2DQ86@1|root,33582@2|Bacteria,1VJ5D@1239|Firmicutes,4HP0T@91061|Bacilli	91061|Bacilli	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IGHDCBEA_01992	861455.HMPREF9184_01752	2.83e-180	504.0	2DNGW@1|root,32XFG@2|Bacteria,1VMS1@1239|Firmicutes,4HVF1@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01994	1123302.KB904164_gene695	5.03e-62	192.0	28WP5@1|root,2ZINV@2|Bacteria,1W3K9@1239|Firmicutes,4I187@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_01996	938288.HG326225_gene1012	9.1e-22	92.8	COG0732@1|root,COG0732@2|Bacteria	2|Bacteria	V	type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
IGHDCBEA_01997	889204.HMPREF9423_1819	1.11e-126	371.0	COG0582@1|root,COG0582@2|Bacteria,1TRCD@1239|Firmicutes,4HDUS@91061|Bacilli,43GBB@68892|Streptococcus infantis	91061|Bacilli	L	Phage integrase family	int2	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IGHDCBEA_01998	469609.HMPREF0847_00371	3.34e-72	227.0	COG0582@1|root,COG0582@2|Bacteria,1TRCD@1239|Firmicutes,4HDUS@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	int2	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IGHDCBEA_02000	1123306.KB904357_gene656	0.0	1048.0	COG0286@1|root,COG0286@2|Bacteria,1UXWD@1239|Firmicutes,4HZE8@91061|Bacilli	91061|Bacilli	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_02001	1121864.OMO_01684	1.47e-226	627.0	COG0582@1|root,COG0582@2|Bacteria,1UH9G@1239|Firmicutes,4HCAS@91061|Bacilli,4AZPY@81852|Enterococcaceae	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
IGHDCBEA_02002	563038.HMPREF0851_00914	1.31e-32	113.0	28SUC@1|root,2ZF42@2|Bacteria,1W27Y@1239|Firmicutes,4HZNS@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
IGHDCBEA_02003	864570.HMPREF9189_0075	3.59e-231	648.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	repB	-	-	ko:K02031,ko:K02032,ko:K15269	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	2.A.7.3.3,3.A.1.5	-	-	ABC_tran,RNA_helicase,Rep_2,Zeta_toxin,oligo_HPY
IGHDCBEA_02004	1095737.HMPREF1110_1887	5.55e-75	235.0	COG1674@1|root,COG1674@2|Bacteria	2|Bacteria	D	ftsk spoiiie	-	-	-	-	-	-	-	-	-	-	-	-	AAA,FtsK_SpoIIIE
IGHDCBEA_02009	862971.SANR_1920	5.66e-42	142.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HN0W@91061|Bacilli,42DSD@671232|Streptococcus anginosus group	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IGHDCBEA_02010	1123315.AUIP01000018_gene2130	0.000342	42.7	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005,ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
IGHDCBEA_02012	768726.HMPREF9178_1579	8.64e-49	166.0	COG0582@1|root,COG0582@2|Bacteria,1TRCD@1239|Firmicutes,4HDUS@91061|Bacilli,2TPBN@28037|Streptococcus mitis	91061|Bacilli	L	Phage integrase family	int2	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
IGHDCBEA_02013	1123312.KB904579_gene623	2.86e-126	362.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1V2NW@1239|Firmicutes,4HGAA@91061|Bacilli	91061|Bacilli	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
IGHDCBEA_02014	1123312.KB904579_gene622	7.69e-61	187.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HNVX@91061|Bacilli	91061|Bacilli	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IGHDCBEA_02015	1123312.KB904579_gene621	4.44e-200	556.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB1	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
IGHDCBEA_02017	936140.AEOT01000001_gene2436	3.66e-68	215.0	COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,3F5IF@33958|Lactobacillaceae	91061|Bacilli	Q	DSBA-like thioredoxin domain	frnE	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	DSBA
IGHDCBEA_02018	1329250.WOSG25_090820	6.87e-18	84.7	COG3548@1|root,COG3548@2|Bacteria,1VFW9@1239|Firmicutes,4HR1J@91061|Bacilli,4AZ3E@81850|Leuconostocaceae	91061|Bacilli	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
IGHDCBEA_02020	1046629.Ssal_02065	3.02e-40	133.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4IPKE@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
IGHDCBEA_02021	1046629.Ssal_02064	6.89e-123	353.0	2DVQ0@1|root,33WQM@2|Bacteria,1VVHE@1239|Firmicutes,4HW4J@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IGHDCBEA_02022	1046629.Ssal_02063	5.05e-179	499.0	COG4509@1|root,COG4509@2|Bacteria,1TRWN@1239|Firmicutes,4HFQW@91061|Bacilli	91061|Bacilli	S	sortase, SrtB family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
IGHDCBEA_02023	1046629.Ssal_02062	2.57e-296	808.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,4HBC3@91061|Bacilli	91061|Bacilli	M	Bacterial capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
IGHDCBEA_02024	1046629.Ssal_02061	5.91e-51	161.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli	91061|Bacilli	T	UPF0237 protein	XK27_08630	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
IGHDCBEA_02025	904306.HMPREF9192_0489	1.27e-308	842.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli	91061|Bacilli	S	UPF0210 protein	XK27_08635	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
IGHDCBEA_02026	904306.HMPREF9192_0488	3.28e-166	464.0	COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HJ9X@91061|Bacilli	91061|Bacilli	G	Phosphoglycerate mutase	gpmB	-	-	ko:K15640	-	-	-	-	ko00000	-	-	-	His_Phos_1
IGHDCBEA_02027	1046629.Ssal_02058	1.13e-177	496.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	yodJ	-	3.4.16.4,3.4.17.14	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
IGHDCBEA_02028	1046629.Ssal_02057	4.75e-132	375.0	COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli	91061|Bacilli	NU	Muramidase (Flagellum-specific)	acmA	-	3.2.1.17,3.2.1.96	ko:K01185,ko:K01227	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,SH3_8,YceG
IGHDCBEA_02029	904306.HMPREF9192_0485	2.32e-237	654.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli	91061|Bacilli	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
IGHDCBEA_02030	1046629.Ssal_02055	6.99e-105	305.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
IGHDCBEA_02031	1046629.Ssal_02054	0.0	1128.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli	91061|Bacilli	O	Heat shock 70 kDa protein	dnaK	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
IGHDCBEA_02032	1095726.HMPREF1116_0195	3.12e-134	382.0	COG0693@1|root,COG0693@2|Bacteria,1UYRW@1239|Firmicutes,4HHW4@91061|Bacilli	91061|Bacilli	S	DJ-1/PfpI family	thiJ-2	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
IGHDCBEA_02033	1046629.Ssal_02052	6.04e-252	693.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
IGHDCBEA_02034	1046629.Ssal_02051	1.76e-177	494.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli	91061|Bacilli	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
IGHDCBEA_02035	1046629.Ssal_02050	7.1e-175	488.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4H9PP@91061|Bacilli	91061|Bacilli	H	phosphomethylpyrimidine kinase	thiD	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
IGHDCBEA_02036	1046629.Ssal_02049	1.23e-105	305.0	COG4720@1|root,COG4720@2|Bacteria,1VBBN@1239|Firmicutes,4HNM0@91061|Bacilli	91061|Bacilli	S	cog cog4720	hmpT	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
## 1820 queries scanned
## Total time (seconds): 1.8876159191131592
## Rate: 964.18 q/s
