LOCUS       c00244_gnlPro..        15005 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IDLKEEIB_264.
ACCESSION   c00244_gnlPro..
VERSION     c00244_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:12:43
            Original ID  :: gnl|Prokka|IDLKEEIB_264
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7834
            Orig. end    :: 22839
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15005
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[17834:21348]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15005
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15005
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             758..2365
                     /locus_tag="ctg244_9"
                     /transl_table=11
                     /translation="MRKNRIRILSMVVFSLCLPFSLFAQIDKDMKEFDDFVKQQQKEFD
                     DFVKQQQKEFDDFVSEQNKEFAEFLKETWKEYDLQKPVVRPQRPEPVKPVSFDHKKPAT
                     KPQEVKVGEVTRLPIPTVTPSATFSPSKGKTPVPVIPGGKDVAVEPEKDSAVLPEIKPE
                     VKPEETVPAKRSLSGVEFSFYSKDCVVNASLKNRLTLKGIAEKDISAGWETLSRSNYQP
                     LIDDCLAFKKDNALNDYGYLLLTRKVATELCGSTHSDEIALMQMFLLSQSGYRVKVARM
                     DNRLTLFYASSNMIYATCFITLNGVNYYRFDTTPDKTNSIYTYNRDFANAKNPVNMNIT
                     TPQSFSGTYVEKTLQAKAYPSVKVCSKVNSGLISFYKDYPQCDFSVYVGAPVSQEVQQT
                     VLPSLQAAIQGKKQSEAANILINFVQTAFDYKTDGDQFGYEKPFFVDELFYYPYSDCED
                     RAVLYSYLVRTLMGLDVVLLEYPNHMATAVCFDENIDGDYITVSGKKYIICDPTYIGAS
                     IGLAMSQFKNVAAKVLKY"
     CDS             2378..3664
                     /locus_tag="ctg244_10"
                     /transl_table=11
                     /translation="MKNIKKYLCAIVMMVISMTAFAQEDVFSGDWLGANKEGDLKVAFT
                     LNCDGNWQLNPYNENARCNGFMEVNMLEPGGRESLMATYEFYVESMNGNELTLSFVGGR
                     PEVDAGISGQCKVVYKDDKLSFSGLDKGGKDAAFNGLTLVKSGSGADAIADAAADDGVP
                     LGVKILAVLQLILYIAVVLFIVGHMFFVWYKGARYKEVFTVEGMLNKRLAAGMPEKMTD
                     EEITEAWKLMDEAFATWTVIEKTDDDEFRKPTKMKQIKKSVLLIDQVIGMCPTDADVIE
                     RLNSLTDVINSGEERHFDGSKKLIWLGVIVGILMYWMMGVGMMFSTLIATGLYVVASRT
                     PQFLIDKRALRGGGNIHNGIFAGVFGLLAGAQTVRTIYKFNDGHKEYSDDHSQHWIALA
                     IGLVILFVLAMMMAFWALLNYLRNYVLYF"
     CDS             3880..4173
                     /locus_tag="ctg244_11"
                     /transl_table=11
                     /translation="LKTKDEIIAILRNFKEEFGERYGIEKLGLFGSVARGEQKEDSDID
                     ICVKLQDPDYFTRMEIKESLEERFNAKVDVVSLTAIMRSLFRNHIEKDVIYI"
     CDS             4190..4543
                     /locus_tag="ctg244_12"
                     /transl_table=11
                     /translation="MLFFVEERINTTIERCGSVISVNDFLASPDKMDIFDATCMRLQTI
                     GETVKNIDNLTNHELLINYAGTPWRSIIGLRNIISHEYLSIDPEEIFKIVKVHLPGLLL
                     AIQQIRNDIAASI"
     CDS             4917..6236
                     /locus_tag="ctg244_13"
                     /transl_table=11
                     /translation="LFSNFYICYQKRTTMKHGIYILTILMALLSLPESGYASIPFFAVA
                     NDTIRRAVIYFDANEAKVDLSYKNNNQVIIILDSLLLGNLNTKYITALNVETFVSPDGD
                     ESYNRSLAARRNDSIKEFLQRYNSDVSVDKIHFFSGGEDWSEFRKLVASDSNLPDREEV
                     LILIDYHKNDVNKRKQLLRKLNRGIAYRYIVHNIFPELRRSVITIVGETSKLGKEAFEP
                     VSSVSGLFVSKQEEALPKDQPDKPVGESEKKQACEVDISEAEGPVKSQTVLAVKNNLLY
                     DLALAPNIEVEIPIGKRWSLNTEYKCPWWLNSKHDFCYQLLSGGMEGRCWLGNRQKRDR
                     LTGHFIGLYAEGGIYDFQLRGDGYQGKYYGAAGVTYGYARQLARHFSLEFSLGIGYLTT
                     EYKKYTPYEGDIVWTNSGRYNFIGPTKAKVSLVWLITTKR"
     CDS             6374..7252
                     /locus_tag="ctg244_14"
                     /transl_table=11
                     /translation="VTDQLPEGVRVIFYPRNGDGRKVDKYLSVRGGEMKVPPGWYSVVT
                     MGYNFNSDRIRIRGEESYESIEAYTEYCNDLGIAGMEKMVWSPDSLYVLNIDELKIEKS
                     EEVLHLDWKMESVVKKYSFAVEAKGLEYVATVVGSIDGLSDCYCIGKGRGVCSSQPIYF
                     EVKKGDNKVTASFTAFKQVKEMTMPTRMSISERETSSEKDAIILILKFIKTDNTVQEAT
                     IDVTEIIGTLENAGTGEDGKPTPPPEIELPPDDKIEVDKPETPPNPDGGGGMGGNVDGW
                     GPEDNVELPVK"
     CDS             7307..8272
                     /locus_tag="ctg244_15"
                     /transl_table=11
                     /translation="MKKILLAVTAALAITGCSQNEEFEAPSQKAEINFNTAVTRATELD
                     TGGLESSGFQVYAYNTKAEEMSAAVTLSTPWINGSATYSDFKWTVSGGPYYWPLAEKLQ
                     FFAYSPKDGVTYTAPNGTTDKGYPKFTYTVGNTAALQKDLVIASVANAQKKTNEAATDV
                     SLTFKHALTQVNIEVTKEAGYTYTISKVELTGIKGSGTFTYAGVNAGTWTAGTETSVSY
                     AYELGDFSDDKTAVKAGNALMLIPQALTDAKISIEYTVEKDGSKIAENSKEVSLTSTAA
                     WAFGKKILYKLTLPIGAQEVGITATVTSWDAEDPVTPTVD"
     CDS             8537..9376
                     /locus_tag="ctg244_16"
                     /transl_table=11
                     /translation="MPSICQGTWDCQICPKAVSNAITHVIYRRGFHKPAQKCEENLILF
                     LMKGEILVNSKEYAGTMLKEGEFILQAIGSMFEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKEVSPPLIYTPLKIIPELQYFLNGSITYLKGDKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYVNSFQYFIIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGIWDDLNNSECSISEICYKYGFESLPHFSNFCKKSFGASPRNLRRQDIS"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg244_17"
                     /sec_met_domain="Fer4_7 (E-value: 1.5e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.5e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(10793..12772)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.3; E-value:
                     4.6e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg244_18"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.5e-62, bitscore:
                     202.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.7e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             complement(12810..13514)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg244_19"
                     /sec_met_domain="SucD_FumR (E-value: 1.2e-131, bitscore:
                     426.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             complement(13726..14595)
                     /locus_tag="ctg244_20"
                     /transl_table=11
                     /translation="MPRDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVVYWFNELPLLCEDR
                     YKEMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLGSFFYPISTYTESFHYFVMQNYSNVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
ORIGIN
        1 ttgctttgca aagagcggct tatctgtatt cattgcagca aggggtacaa ttgagacttc
       61 tctcggatgt tttttccacc atggagactg ccagtaatac atacgaagac caaagaaaca
      121 aaatgcttgt actgggagtg atcgaacatc ccgttcaaca tgtttcctac cggattgagc
      181 atgaatatac ttctatattt ggagagaaat ttctggaggt atcttttact ccatcgaatg
      241 atagttgcga tttttcttat cattccgtta gtgagttgat gcttttgttt acgaaagaaa
      301 gggttgagga agaagaggtg aaattcaatt tattgttgga atcggatagt tgtagggagc
      361 aatcagacca gtcatggttt cagcttaagg gaacacagtc atctcctcaa ataatttcat
      421 atttgaacgg agttgaaatt tgttcttcac aagaaggctg ttggtatgaa gatgccggtt
      481 ccggaggtca ggacggattg gagaagatgg atatgaggaa tgccttttgg aatgcctata
      541 tgtcttcttt agtgaaggcg ctgttgttat atccgttttc tgatgtaaat gtcaagcagg
      601 tggacgatcg ttttaatggt ggcactgatt ccggttgtgg tttgtatcgg gagaaggttg
      661 tcgccgtctt gtccattttc ccctttatca aagatatacg gaataataag ctgtgtgtag
      721 attggcagat aacagaacaa caaaatataa taaggaaatg aggaaaaata ggatacgaat
      781 actatctatg gtagtttttt cattgtgttt gccgtttagt ctttttgcgc aaatagataa
      841 agacatgaag gagtttgacg attttgtgaa gcagcagcaa aaagagtttg atgattttgt
      901 gaagcagcag caaaaagagt ttgatgattt tgtgagcgaa cagaataagg aatttgccga
      961 attcctgaaa gaaacctgga aagagtatga tttgcagaag ccggtggtac gtcctcaaag
     1021 accagagcct gtaaaaccgg tcagctttga ccataagaag ccggcaacaa aaccgcaaga
     1081 ggttaaagta ggggaggtga cccgactccc cattccgaca gtgactccaa gtgcgacatt
     1141 ttctccttca aaagggaaaa caccggttcc ggttataccg ggaggtaaag atgtggctgt
     1201 agaaccggaa aaggattctg cggtgctccc tgaaataaaa ccggaagtga agcctgaaga
     1261 aaccgttccg gccaaacgct cactttccgg tgtagagttt tcgttctaca gtaaagattg
     1321 tgttgtcaat gcttcattga agaaccggct cactttaaaa gggattgcag agaaagatat
     1381 ttctgccgga tgggagacgt tatcgcgtag caactatcag cctttgatag acgactgtct
     1441 ggcttttaaa aaggataatg ccctgaatga ctatggctat ctgctgttaa cgaggaaagt
     1501 tgctactgaa ctatgtggaa gtactcattc cgatgaaata gctcttatgc aaatgtttct
     1561 cctttctcaa tcgggatata gggttaaggt ggcgcgtatg gataaccgcc ttactttatt
     1621 ctatgcttcg agtaacatga tttatgctac ctgttttatt actttgaatg gagtaaacta
     1681 ttacaggttt gatactaccc cggataaaac taattctatt tacacttaca accgtgattt
     1741 cgccaatgcg aagaacccgg taaatatgaa tatcactact cctcaatcct tttcaggaac
     1801 ttacgtggag aaaacattgc aagcgaaagc ttatccatcc gtcaaagtct gttcgaaagt
     1861 aaattcggga cttatttcct tctataagga ttatccgcaa tgtgactttt ctgtctatgt
     1921 gggagctcct gtcagtcagg aagtacaaca gacggtgctt ccatcattgc aagctgccat
     1981 acaagggaaa aaacaatcgg aagctgctaa tatactgatt aatttcgtgc agacagcttt
     2041 tgattataag acagatggtg accagtttgg ttatgagaag cctttctttg tggatgagct
     2101 gttctactat ccttattccg attgcgaaga ccgtgctgtg ttatactctt atttggtacg
     2161 tactcttatg gggcttgatg ttgtattgtt ggaatatccc aatcacatgg caacagcggt
     2221 ctgttttgat gaaaacattg acggagatta tataactgta agcggaaaga agtacattat
     2281 ttgtgatcct acttatattg gagcttctat cgggcttgcc atgtcgcaat ttaagaatgt
     2341 ggcagccaag gtgttgaaat attaatttta ttatattatg aagaatatta aaaagtattt
     2401 gtgtgccatt gtaatgatgg ttatttcgat gactgcattt gcgcaggaag atgtttttag
     2461 cggtgactgg ctaggagcaa ataaagaagg cgatttaaag gttgcgttca cattgaattg
     2521 tgatggtaat tggcaattga atccttataa tgagaatgcc agatgcaatg gatttatgga
     2581 agtgaatatg ctggaacccg gtggaaggga atctttgatg gcaacttatg agttttacgt
     2641 cgagagtatg aacgggaatg aactgactct ttcttttgta ggcggacgtc cggaggttga
     2701 tgccgggatt tccggtcaat gcaaagtcgt ttataaagat gataagttgt cgttttccgg
     2761 acttgataaa ggcggaaaag atgctgcctt taatggattg acacttgtaa aaagcggtag
     2821 tggagctgat gcaatagctg atgctgcggc ggatgacgga gttcctttgg gagtaaagat
     2881 attggctgtt ctccaactga ttttgtatat tgccgttgtt ttatttattg tggggcatat
     2941 gttttttgta tggtataagg gcgcacgtta taaagaggtt tttacggtag aaggaatgtt
     3001 gaataaacgc cttgcagccg gaatgccgga gaaaatgacg gatgaagaga taacggaggc
     3061 gtggaagctg atggatgagg catttgctac ttggacggtg attgaaaaaa cagatgatga
     3121 tgaattcaga aagccgacaa agatgaagca aattaagaaa tctgttcttt tgattgatca
     3181 ggttatcggt atgtgtccta ctgatgctga tgtcatagaa cgcttaaact cattgactga
     3241 tgtgattaat agtggtgaag aacgtcattt tgatggttcc aagaaattaa tctggttagg
     3301 tgtcattgtg ggtatcttga tgtattggat gatgggagtc ggtatgatgt tttctacttt
     3361 aatagctacc ggtttgtatg tggtagcgag caggacgcct caattcttaa ttgataagcg
     3421 ggcacttcgt ggcggtggaa atattcataa tggtattttt gccggagtgt tcgggttatt
     3481 ggcaggagcg cagacagtgc ggacaatata caagtttaat gatggtcata aagaatattc
     3541 tgatgatcat tcacaacatt ggattgcttt ggcaatcgga cttgtcattt tgtttgtatt
     3601 ggcaatgatg atggcgttct gggcacttct gaactattta cgtaattatg ttctgtactt
     3661 ttgatggata aaactaacat ggttgttaat aatggattcg gcagcataat taggctattt
     3721 atgttttgaa gtagaattta gagtagtagg tgtacagggg atcgatgaaa attcgatgac
     3781 ctgtgcatct ttttttaatt agtgatacta caaaatatga ttaagaactt gctaattcca
     3841 atataaattt taatatttac attataacaa tagtgtcaat tgaaaacaaa agatgaaata
     3901 atcgctattc tccggaattt taaggaagaa tttggggaga gatatggaat tgaaaagttg
     3961 ggactttttg gttctgtggc tcgtggtgag cagaaagagg atagtgatat tgatatttgt
     4021 gtaaagcttc aagatccgga ttattttact cgaatggaaa taaaagagtc attagaagag
     4081 cgttttaatg caaaagtgga tgtcgtgtct ttaaccgcaa ttatgcgtag tttatttcgc
     4141 aatcatatag agaaagatgt aatctatatc taatgctgac atattggata tgcttttttt
     4201 tgtagaagaa cgtattaata caactataga aagatgtggt agtgtcattt ctgtaaatga
     4261 tttcttagct tctcctgata agatggatat ttttgatgcg acttgtatgc gtttgcaaac
     4321 cataggtgag actgttaaga atatagataa cctgactaat catgaattat tgataaatta
     4381 tgccggtact ccatggagga gcatcattgg actgcgcaat attatttctc atgaatattt
     4441 atctattgac cccgaagaaa tttttaaaat agtaaaagtg catctacctg gattgcttct
     4501 tgcaattcag cagatcagga atgatattgc tgctagtata tgagaccttt gtagcttttc
     4561 tattttttat tatgcaaacg gtagtcttta ggtgccactc ccatccgctt tgtacactcc
     4621 ttatagaaat gtgatctatt cataaaccca ctttgataca tgatttcttt aatgaaattt
     4681 ttgggtgggg ataaaatatc tcgtagaaaa ttcctggcga ctcccgatca tagttatttc
     4741 ccgatttgta tagaggagat gaagcttggc atccatgtgt atgtggaaaa gccgcctgtc
     4801 agaacttcct ttttctgttt attattgacc ttaaactctc aaaacttgca aaatagtttc
     4861 aatcgtttca cagaaccttt catgcctttg tttttgttct aaaagtatga ttcgatttgt
     4921 tttctaactt ctatatttgt tatcagaaac gaacgacaat gaaacatggt atctatatat
     4981 tgactattct tatggcttta ttaagccttc cagaaagtgg gtatgcttcg attccatttt
     5041 tcgctgttgc gaatgataca atccggcggg cagtgatata ttttgatgcg aatgaagcga
     5101 aagtggatct tagttataag aataataatc aggtaattat aattttagat tctttgcttc
     5161 tcggaaattt aaatacgaaa tatataacag cgctgaatgt ggaaactttt gtttctcctg
     5221 atggtgatga atcttataat agaagtttgg ctgctcggag aaatgattcg ataaaggaat
     5281 tcttacaacg gtataattcg gatgttagtg ttgataagat tcattttttt tcagggggag
     5341 aggattggtc ggagtttcgt aagttggtgg catccgactc taacttacca gatcgggaag
     5401 aagtgctgat attgattgat tatcataaga atgatgtcaa taaacggaag caactgttgc
     5461 gaaaattgaa tcggggaatt gcttaccgat acattgttca caatatcttt ccagaactgc
     5521 ggagatcggt tattacgatt gtcggagaaa cttcgaaatt aggtaaagag gcttttgaac
     5581 cggtatcttc tgtctccggg ttgtttgttt caaagcagga agaggcgctt ccgaaagatc
     5641 aacctgataa gcctgtggga gaaagtgaaa aaaaacaggc ctgtgaggtc gatatatcgg
     5701 aggcagaagg gccggtgaaa agccaaactg tacttgcagt gaagaataat ctgttatatg
     5761 atttggcatt ggcgccaaat atagaagtgg aaattccgat aggcaagagg tggtctttga
     5821 atactgaata taaatgtccg tggtggctga atagcaaaca tgatttctgc tatcagctcc
     5881 tttcgggagg gatggaagga cgttgttggc tgggaaaccg tcagaagcgt gaccgattga
     5941 ccggacattt tatcggactt tatgctgaag gcgggatata tgacttccag ctgcgtggag
     6001 atggctatca aggtaagtat tacggagctg cgggagtgac ttatggatat gcacggcagt
     6061 tggcacggca tttttccctt gaattcagtc ttggcatagg gtatttgaca acagaatata
     6121 aaaaatatac tccttatgag ggagatattg tatggacaaa tagtggacgt tataacttta
     6181 ttggtcctac caaggcgaaa gtttctttgg tatggttgat aacaacaaag agataggagg
     6241 gcgtaatgcg aaatacaaga tacaggtttc ttgtgctttt gtcctcgctg ctgatgctaa
     6301 ctggatgtag ccgtcgcgat atattggatg attatccgta agtggggtag atataaagct
     6361 ggattgggat ggagtgacag atcaactgcc ggagggagtt cgggtgattt tttatccgag
     6421 gaacggagat ggcaggaaag tagataaata cctttcggtg cgaggcggag aaatgaaagt
     6481 tcctccggga tggtattcgg tagtaactat gggttataac tttaactcgg atcgtatacg
     6541 aattagagga gaagagtcct atgaatctat agaagcttat acagaatatt gcaatgattt
     6601 ggggattgca ggaatggaaa agatggtttg gtcacccgat tcgttgtatg tattgaatat
     6661 agatgagctg aaaatagaga agagtgaaga agtgcttcat ttagactgga agatggaatc
     6721 tgtggtgaag aaatattctt ttgcagtaga ggctaaaggt ttggagtatg ttgcaacagt
     6781 ggtagggagc attgatggat tatccgattg ttactgtata ggcaaaggtc gtggagtgtg
     6841 tagctcacaa cctatctact ttgaggtaaa gaagggagac aataaggtaa cggcatcttt
     6901 caccgctttc aaacaagtaa aggaaatgac aatgccgacg cgaatgtcaa tatcagagag
     6961 ggaaacttct agtgagaaag atgctataat attaatattg aaatttatca aaacagataa
     7021 tacagttcag gaagcaacaa ttgatgttac tgaaataata ggtacacttg aaaatgctgg
     7081 aacaggggaa gatggaaaac caaccccacc accggagatt gagttaccgc ctgatgataa
     7141 gattgaagtt gataagccgg aaacaccacc gaatcctgat ggaggtggag gaatgggtgg
     7201 caatgttgat ggatggggac ccgaagataa tgttgagtta cccgtgaaat gaaatagatg
     7261 ctataaacaa aatataacaa tattataaac ttaaaaaaat acagttatga agaagatttt
     7321 attggcagta acagctgctt tggcaattac gggttgctca cagaatgaag agtttgaagc
     7381 cccttcacag aaggccgaaa ttaattttaa tacggcggta actagagcta ctgaactgga
     7441 tacaggcggt ttagagagtt ctggctttca ggtttatgcg tataatacga aggcagagga
     7501 gatgagtgct gcggtgactc tttcgacacc atggataaat ggttctgcta cttattcgga
     7561 ttttaaatgg acggtatctg gaggtccata ttattggcct cttgcagaaa aactgcaatt
     7621 ttttgcatac tctccaaaag acggagttac atatacagct ccgaatggta ctactgataa
     7681 aggatatcct aagtttactt atacagtggg aaatacagct gcccttcaaa aggacttagt
     7741 gattgcatct gtggcaaatg ctcaaaagaa gacaaatgaa gcagcaacag atgtttcttt
     7801 aacttttaaa catgcattga ctcaagtaaa tatcgaggtg acaaaagagg ctggttatac
     7861 ctatactata tctaaagtgg aattgactgg aattaaggga agtggaacat ttacatatgc
     7921 aggtgttaac gcagggactt ggactgcagg tacagagaca agtgtctctt atgcatatga
     7981 acttggggat ttttcagatg ataagacagc tgtaaaagca ggtaatgcgt tgatgttaat
     8041 accgcaagct cttactgatg caaaaatatc tatagaatat accgtagaga aagatggaag
     8101 taagattgct gaaaatagta aggaagtatc tttgacaagt actgctgcat gggcgtttgg
     8161 aaagaaaata ctatataaac taacattgcc tattggtgct caagaagttg gtatcactgc
     8221 aactgttact agttgggatg ctgaagatcc tgtaactcca actgttgact aacacaagat
     8281 taaatctatg gaaccgatgt aatttgtatg ttacatcggt tcttcttgtg ttttggaatt
     8341 atgatagaaa atataaccta gtttctccag aaaaagactg ggaattttaa ttctatatgt
     8401 tacttacatt tttgtagtgg ataccttttt tctcttacct aacctctttt tcacttttct
     8461 ctcttttttt atggcaatat gaaagatttc atatattttt gctggcagca taaacaaaaa
     8521 caaacacagt cagcgtatgc catctatttg tcaaggaacc tgggattgtc aaatatgtcc
     8581 aaaagcggtg agtaatgcca ttactcatgt gatttatcgg cgtggttttc ataaaccggc
     8641 tcaaaagtgt gaagaaaatc ttatcctttt tttgatgaag ggagaaatac tggtcaatag
     8701 taaagaatat gcggggacta tgcttaaaga aggtgaattt attcttcagg ctattggttc
     8761 tatgtttgag atgcttgcta tgactgaatg tgagtgcatt tattatcgtt ttattcagcc
     8821 cgaactgttt tgtgatttcc gtttcaatca tatcatgaag gaagtatctc ctccacttat
     8881 ttatactcca ttaaaaataa ttccagaact acaatatttc ctcaatgggt ctattactta
     8941 tttgaaaggg gataaagtct gtcgggattt gctatctctg aaacgaaaag aattagcgtt
     9001 cgtgttggga tactattatt ccgattatga tctttcgagc ttggtgcatc cactctctaa
     9061 atatgtaaac agtttccaat atttcattat tcaaaactat aagaaagtaa agacagtgga
     9121 agaactggca caattgggtg gatatactct tagtacattc cgtcgtatct tcaataacgt
     9181 ctttcatgaa cctgtttatg aatggatgct ggcgagacgt aaagagggca tttgggacga
     9241 cttgaacaac tctgaatgta gcatttcgga gatatgctat aaatatggtt ttgaatcttt
     9301 accccatttt tctaatttct gcaagaaatc ttttggtgcc tctccacgta atttacgtag
     9361 gcaagacatt tcataaatgc aactatgtaa gataattgcg gttcaccggt ttcacccaat
     9421 tctctaaatg ccgatgaata aggtaacagc gggtgaaagc aagggagaaa ttcaggtgaa
     9481 actgaacctt cttggtttca cctattgagt ttattcatac cgactgttgg acatatagct
     9541 ccaaggtgtt ggatatatag ctccaagatg ctggatatat agatgcaaca actcaagtat
     9601 taacacatga gaactaaggt gttaagactt ggcggccaaa gtattacatc cgtacagttc
     9661 actcattaat acctgaaagc ggatttgcta taagcatatc cggattagct ataatgataa
     9721 ttgttttagc tcaagggata ttttaataag acaggtgaaa gcggtaacga atgattttac
     9781 cttatttcag tcctcgcttt cacccgtaat tctctcattc ataccagttt tggctataag
     9841 gtgaaatcgg tgaaacttat gaattaaaag ttcatgttac tgatccgtat taataataat
     9901 tgtgatctac tcatatataa agaaatcccc tgtcgaacta gccggcaggg gattctgtca
     9961 ttaatcaaat taagctctcg ctattgaaat ctagcaattt ctagtctttt aattttgcga
    10021 tgatgaagtc gcggttcaag cgagcgatgt tgctgataga aatattcttc ggacattcag
    10081 cttcacaagc acgagtgttt gtacagttac cgaatcccag ttcgtccatc tttgacaaca
    10141 tagcttttgc acgacgcaaa gcctccggtt taccttgcgg cagcaagttc aactggctaa
    10201 cttttgcaga aacgaacaac atagcagaac cattcttaca tgcagctaca caagcaccgc
    10261 aaccgataca agaagcagca tccatagctt cgtcagcgat aggtttcgcg atcaggatag
    10321 cgttagcatc ctgcggagca cctgtgcgta cgcttacata accaccagct tgcataatct
    10381 tgtcgtatgc agtacggtct accatcaagt ctttgatgac agggaaacca gccgaacgcc
    10441 aaggttcaac agtgatggta tcaccgtcgt tgaaacgacg catatagatt tggcaagtag
    10501 tagcacctgt tgcaggaccg tgcgggtgtc cgttgatgta aagagaacac ataccgcaga
    10561 taccttcgcg gcagtcatga tcgaatacta ccggttcttt tctttcgctg atgagctgtt
    10621 cgttcagaat atccagcatt tcgaggaagg aagtatcacc ggggatatct ttcatttggt
    10681 aggtttcaaa agcaccttta gctttcggac cagcttggcg ccataccttc agtgtaaatg
    10741 atatattttt atccattttc ttctaattct tttaaatgtt taacttcacc gattagctct
    10801 tgtagttacg agtctgaacc ttgatagctt cgtataccag cggttctttg tgcaataccg
    10861 gagccttttc atcgtcacct tgatattccc agcatgctac atagaagaag ttttcgtcat
    10921 cacgttttgc ttctccttct tcagtctggt attcttcacg gaagtgacca ccacaacttt
    10981 cgttacggtt caatgcatcg taagcaacaa gctcacccat agtgatgaag tcgtacagac
    11041 ggattgcttt gtcaagctct acgttcatac cttccttaga accggggata aacaagttcg
    11101 tttcgaattc cttgcggatt tctttcagtt cggcgatacc tttcttcagg ccttctgccg
    11161 tacgtcccat acctacatat tcccacatga catgacccag tttcttgtgg atagaatcaa
    11221 cagattcttt accctggatg ctcatgaact tgtcgatctt agcttgaact gctttttcag
    11281 cttcagcaaa ttcaggaaga tcggtagaga aacgaggaac agtgatctgg tctgccagat
    11341 agttctggat agtgtaaggc aatacgaagt aaccgtcagc caaaccttgc atcaatgcag
    11401 aagcaccgag gcggtttgca ccgtggtcgg agaagttaca ttcaccgata gcgaacagac
    11461 ccttgatagt ggtttgcagt tcgtagtcta cccagatacc acccattgta tagtggatag
    11521 ccggataaat catcatcggg ttataatatt tcacaccact gatttcttta gccagttcgc
    11581 ccggattaac gtcagtgatt tcttcgtaca tatcgaagag gttaccataa cgttgaagaa
    11641 caacgtcgat acccaaacgg ttgatagctt cagagaagtc gaggaatacg gccaaacctg
    11701 tgttgtttac accgaaacca gcgtcgcaac gttctttagc ggcacggctg gcaacgtcac
    11761 gcggaaccag gttaccgaat gccggatagc ggcgttccaa gtaatagtcg cggtcttctt
    11821 ccggaatatc acttcctttg atttcgcctt tctggagttt tacagcatct tctttcttct
    11881 tcggaaccca gatacgaccg tcgttacgga gagattcaga catcaaagtc agcttagact
    11941 gcttgtcgcc atgtaccgga atacaagtcg ggtgaatctg aacgtatgca ggatttgcga
    12001 atacagcacc cttgcggtag caagagatag cagctgtaca gttacaaccc atagcgttag
    12061 tagacaggaa gtaagcgtta ccataaccac cagtagcgat tactacagcg tgagcggcga
    12121 aacgttccaa ttcgcctgtt acaagatttt ttgcgatgat accgcgggca cgtccgtcaa
    12181 cgatgacaac atcctgcatt tcgtagcggg tatacagttt aacagtacct acgtttacct
    12241 gacggctcaa tgcagagtaa gcacccagca gcaactgctg accagtctgg cctttagcgt
    12301 agaaagtacg ggatacctgt gcgccaccga aagaacggtt atccagtgta ccgccatatt
    12361 cgcgagcgaa aggaacacct tgcgctacac attggtcgat gatagcgtta gacacttcag
    12421 ccagacgata tacgttagct tcacgggcac gatagtcgcc accttttaca gtatcgtaga
    12481 acagacggta aacggagtca ccgtcatttt gataattctt tgcagcattg ataccaccct
    12541 gtgcagcgat agagtgtgca cgacggggag aatcctgaat acagaaattg aatactctga
    12601 aacccatttc accaagtgaa gcagcggcag aagcacctgc cagacccgta cccacaacga
    12661 tgatgtccaa acgacgttta ttagcggggt tcaccaattt ctggtgagct ttatagttgg
    12721 tccatttctc agccaccggg ccttctggaa tttttgaatc tatcttgatc ataatattat
    12781 ttacaattta atcatttaca atttactatt tagcaagcac cgccacaaat cagtgttttc
    12841 acgaagaata ccactactac cagtgcgaaa ccgagtacaa caatcgtaga atagatgtta
    12901 gaaatacatt tccaacgatt gatccatact ttgttgttcc atcccagtga ttgcatagag
    12961 ctccagaaac cgtgagtcag gtggaaccac aaagcaaaca gccaaacgag gtaaagaact
    13021 acgtaaaccg ggctagagaa agtctgctgg atgtgataag caccgttagc ggcataagcc
    13081 agcgtcagtg tatcagcgtg catgcccatg ttgtgcatca gttccggcaa ctgcattttt
    13141 gcccagaagt tgaagaggtg caaaccaaga cctacgataa cgatcagacc cagcaccaac
    13201 atgttttgag atgcccattc tacagttttt ggtttgtcaa ccactgcata gcgttcgcta
    13261 ccacgcgctt tgcgattctg cattgtcagc cagaatgcgt agatgatgtg aatcacaaaa
    13321 agagcggcta gtcctgcggt agccactaac gcataccagt ttgctcccag gaactcacaa
    13381 atcatgttgt aaccatcagc cgagatgatt gcaaccaagt tcatcgccat gtgaaatgtt
    13441 agaaacagga caagggcgat accggtaacg ctcatcacca ctttccttcc tacagatgaa
    13501 ttacttaacc acataaatga ttgaatttaa attatttaat tgttagaact aaaatttcga
    13561 cgttttacac ctcttacaga ctgcaaaaat aggggaaata gattgattga gcaaggaatt
    13621 aaagaaataa ttctttaata atggatcaat acgccaatgt gtcaatatgc cagccagtat
    13681 gcgcgcatgg tgcaactgat tggcacatta gtaggatggg gctgtttatt gtacctttcc
    13741 gattttctca ccaccggctg cttttttgcg taaagcgcgt ggggtatcgc caaaagagtc
    13801 tttacagaag tgtgcgaaat gcgacaggga gtcgaatccg tatctgttac agatttcagt
    13861 aattcgcatt ttggtgtgct gcaggtcttc caggattcct tcccgtttct tttccagtat
    13921 ccattcgtat acgggcacac cgtagaggtt tttgaaaagt cggcggaaag tagtggtcgt
    13981 atatcctccc agatgcgcaa attcttccac gttcttcacg ttactgtaat tctgcatgac
    14041 gaaatagtgg aaactttccg tataagtgct gatcggatag aagaatgaac ccagttgggg
    14101 cagcggatag aagttggtaa tcaagaaaac cagttctttg cattttaagt cgatatactt
    14161 gctgcaaggg ttttcttcag cgaggaattc gggcatactg gtgacaaggt ggtaaagcct
    14221 ttcgctcata atcagtggag tgtaggtcaa aggagcttcc gcctgttcca tcatttcctt
    14281 atatcggtct tcgcaaagca aaggcagttc gttgaaccag tagacaacgt attcaacatc
    14341 tgtcagtgcc agtatttcga ccttggagcc aatagcttgc aaaacaattt gtctctcgcg
    14401 taacgttatt ccgggatgct cttcgctatt gataagtaat tcgcccttta tcataaaaag
    14461 catacaattc tgcgtacact tatccttggg gatatgctct cctttaggta agtttctata
    14521 tacaaggata ttctcaacat tttttggaca tcccgtacag ttggtatatt gtatgcaaaa
    14581 tgaatctctt ggcatgagtt ttatgcgtga tttattatct taacggaaca aagataggct
    14641 ttttttgcgg aaaatggaac tctttctttt atttatgttt tagtagaaac ctgcaaatat
    14701 tattcttatc cctttggatg atgttagaga attcaatatt tatctgttgt aaatttctga
    14761 atagaaaact ttatgttgat ttttggaagt attatagttg tttttgaaca tctgtttccc
    14821 tttgatatgc gtatttttgc aatctaaacg ttttaattat caatcattat gctaatgcta
    14881 agaaaaattg tattcttctt ctttttttgt ttgttggatt atcattgttt gcacagcaag
    14941 actatatggt ctttttttgt ttgttggatt atcattgttt gcacagcaag actatatggt
    15001 cagtt
//
