LOCUS       c00010_gnlPro..        16288 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PEMBJLGJ_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:32:28
            Original ID  :: gnl|Prokka|PEMBJLGJ_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16288
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16288
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2736:6288](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2737..6288
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16288
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16288
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(164..1363)
                     /locus_tag="ctg10_1"
                     /transl_table=11
                     /translation="MTKKALYIFNPEHDLALASGETNYMAPASARQMASELALLPMWYA
                     EEGSVVLAPSAYNLDYVKKIQELLGLSVDLMTEPELASERNLDIRPWGWDIAIRKRLLD
                     LGVEESELPSIEQLDKLRFCSHRSCAVGLLPQLQLGACFCGESFYLTFPEEWKSFVESH
                     DTCLLKAPLSGSGKGLNWCKGVYTPSISGWCSRIGNQQGGVIGEPLYNKVEDFAMEFRS
                     SGNGRFGFAGYSQFRTGGSGAYEGNLLISDAAIERNLLEYIPVEEIYKLRDRLEQELSL
                     RFGTIYNGYLGVDMMICRFPESPVYRIHPCVEINLRMNMGVVARHIYDHYIYPTSTGAF
                     QISYYPTEGTAWRAHKEMEEAYPLEIEQGRIKSGYLSLVPAHKKSSYRAWVFISKSVFL
                     "
     CDS             1526..2704
                     /locus_tag="ctg10_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             2737..6288
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.8e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 5.8e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.2e-08, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00016, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 9.8e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPEAKEVLKAWIENMYDADKTKE
                     LAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(6249..6398)
                     /locus_tag="ctg10_4"
                     /transl_table=11
                     /translation="MNSSGKKVVLFMLDRVHTIKNGNLLQDYRFLFIGYYYYSAPQFSL
                     AKRL"
     CDS             complement(6440..7312)
                     /locus_tag="ctg10_5"
                     /transl_table=11
                     /translation="MHVRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAM
                     SHLAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEF
                     LGEVYGEARVGLVVPQYVTIQSINELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGL
                     DGYTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEI
                     HAIAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVD
                     SWIPKSENK"
     CDS             complement(7330..8154)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.3e-28, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLATLAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(8151..9377)
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGD
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(9676..10014)
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             10098..11393
                     /locus_tag="ctg10_9"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPNKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKRITDLNIPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANISKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNPYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQKNQRWWNKPKTNKLIMN"
     CDS             complement(11535..14417)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 62; E-value: 2.1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3e-19, bitscore:
                     62.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYTKWITVLLCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLHRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKEMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDILEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQR
                     RMLLLVQRNVNILLRLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAAARKKH
                     IHFSFDYMPDTDYRTLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIR
                     FTVANTGSMISAEHIRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQG
                     TIFTVDLPVQTCETVVSENSPAFSVPATSVTSTDAATSAVAGAPVTPATSGYSGSSSLN
                     DALTYEEEELEKSYDSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAADGSEGIRKAMK
                     YVPDLIISDVMMPGMDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYI
                     SKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGD
                     SNLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGY
                     EVGFSSPSYFTKCYREQFGESPTDLLKRKG"
ORIGIN
        1 gtataacaag cgaagttgtc aactaaatcc agtacagtac atcacatggc atgtgattac
       61 ttgtttcatg caatgaaact ttttgtttct cggtgtggaa ccaatggttt cactgcatga
      121 aactatcagt ttcacaccga gaaaccataa cttcgatata atatcacaaa aacacgcttt
      181 ttgagataaa cacccacgcc cgataactac tctttttatg agccggcacc aatgacaaat
      241 agcctgattt tattcttcct tgttctattt ccaaaggata agcctcctcc atttctttgt
      301 gtgctctcca ggctgttcct tccgtagggt aatagcttat ttgaaaagct cctgttgaag
      361 taggatagat ataatggtca taaatatgac gcgctactac tcccatattc atcctcaagt
      421 tgatttccac gcaaggatga atccgataaa caggagattc tggaaagcga cagatcatca
      481 tatccactcc caaataacca ttataaatgg ttccgaaacg gagggataat tcttgttcaa
      541 ggcggtcgcg caatttataa atttcttcga cagggatata ttccaaaaga ttccgttcga
      601 tggctgcatc tgaaatcagc agattacctt cgtacgcccc acttccaccc gtacggaatt
      661 gagagtatcc ggcaaagcca aatcgaccat tacccgaaga acgaaattcc atagcaaaat
      721 cttccacctt attatataga ggttcgccaa taacacctcc ttgctggttg ccaatgcgtg
      781 agcaccaacc ggaaatggaa ggagtatata cacctttgca ccaattcaac ccttttccgc
      841 taccggataa aggagctttc agtaaacaag tatcatgtga ttctacaaat gacttccatt
      901 cttcgggaaa cgtcaggtaa aaagactctc cacaaaaaca ggctcccagt tgtagctgtg
      961 gtaataatcc cacagcgcag gaacgatggg aacagaaacg cagtttatcc aattgctcaa
     1021 tagaaggaag ctcgctttct tccactccca aatccaacag tcgttttctt attgctatat
     1081 cccagcccca aggacgaata tccaaattcc gctccgaagc aagttcaggt tctgtcatca
     1141 aatcaaccga aagtcctaat aattcctgta tcttcttcac atagtcgaga ttataagcgg
     1201 aaggagccaa tacaacactt ccctcttctg cataccacat cggcaacaaa gccaattcgg
     1261 atgccatctg ccgggcggaa gccggtgcca tatagtttgt ttcaccgctg gctaacgcca
     1321 aatcatgttc cggattgaat atataaagag ccttttttgt cattttaaac gaattcaaaa
     1381 ctttattctg caaatatata caggaaatag tcaggaatgg ctacaataaa cagaaagttc
     1441 taattaaact cacaattttg ccatctctac tttgcaaatc ctaaaaaaag cagtatattt
     1501 gccacccgaa aaacaaagaa ctgaaatgga atcattctat cgcacacacg cctacctcgt
     1561 tgagcacacc aatgcccccg ttcgccgcga tcttatggac gagatcgact ggagcgaccg
     1621 cctgattggt atcaaaggga cacgtggcgt aggaaaaacc actttccttc tccaatacgc
     1681 caaagaaaaa tttgggaacg accgctcctg cctgttcatc aacatgaaca acttctactt
     1741 ctctggccac agcattgtag actttgctaa cgaattccag aaacgtggtg gaaaagtatt
     1801 gttgatcgac caagtgttca aacacccgga atggagcaga gagttgcgca tgtgttacga
     1861 ccgttttcct aatttgaaaa ttgtctttac cggctcatct gtaatgcgac tgaaagagga
     1921 aaatcttgaa ttgcgtgata ttgcaaaaag ctataacctg cgcggatttt ctttccgcga
     1981 atacctgaac ttacaaacag gcatgaaatt cagggcctac agtctcgaag aaattcttag
     2041 cactcacgaa cagattgcca aaggagtact ctctaaagtt cgtccgctgg attacttcca
     2101 ggattacctg catcatgggt tctatccatt cttcctcgag aagcgtaact tttcggagaa
     2161 tttgctgaaa acgatgaaca tgatggtgga agtagatatc ctgctcatca aacaaattga
     2221 actgaaatat ctttcaaaga taaaaaaatt actatatttg ctcgctgtcg acggaccgaa
     2281 ggctcccaat gtgagtcaac tggcaagcga catacagaca tctcgcgcca cggtgatgaa
     2341 ctatatcaag tatctggcag atgcgcgact cattaatctg gtttatccga aaggagaaga
     2401 atttcctaaa aaaccttcca agataatgat gcacaactcc aacctgatgt attccatcta
     2461 tcccgtgaaa gtggaggagc aggatgtact cgacacattc tttgcaaatt ctttatggaa
     2521 agaccataag gtacataaag gagataaaaa cgtctctttt atggtggacg aagtaatgcc
     2581 gttcaaaatt tgccaggaag gagcaaagat caagaacaat ccgaatgtga cgtacgcgtt
     2641 gcataaggct gaaataggtc ggggcaacca gatacctctc tggatgttcg gctttttata
     2701 ttaaaagatt tatttactta aatatttaat ttagttatga ctaaacagaa gaaattcatc
     2761 acttgtgatg gtaaccaggc tgcagcgcat atctcgtata tgttctctga agtagctgct
     2821 atctacccca tcactccttc ttcgactatg gctgagtacg tagacgaatg ggctgccgca
     2881 ggacgtaaga acatcttcgg cgaaacagta ttggtacagg aaatgcaatc tgaaggtggt
     2941 gctgccggtg cagttcacgg ttctcttcag gctggtgcgt tgactactac ttacactgct
     3001 tctcaggggc ttctcctgat gatccctaat atgtacaaaa ttgccggtga gttcttgcct
     3061 tgcgtattcc atgtatctgc tcgtacattg gcttctcacg cattgtgtat cttcggtgac
     3121 caccaagacg taatgtcagc tcgtcagact ggctttgcga tgttggctga aggctctgta
     3181 caggaagtta tggatttggc tggtgttgct cacttggcta ccatcaaatc tcgcgttccg
     3241 ttcatgaact tcttcgatgg tttccgtaca tctcacgaaa tccagaagat tgaaatgttg
     3301 gaaaatgatg atcttgctcc gctgatcgat caggaagctt tggctgaatt ccgtgcccgc
     3361 gcactgaatc cgatgaatcc ggttgctcgt ggtatggctg aaaaccccga ccacttcttc
     3421 caacatcgtg aatcatgtaa caactactat gaagcagttc ctgctatcgt agaagaatac
     3481 atgaatgaaa tttctaagat tacaggtcgt aaatacggtt tgttcgatta ctatggtgca
     3541 gaagatgcag aacgcgtaat tatcgctatg ggttctgtaa cagaagctgc ccgcgaagct
     3601 atcgaccact tggtagcaaa tggcgaaaaa gtgggtatgg ttgccgtaca cctgtatcgt
     3661 ccgttctctg ctaaacactt cctggctgct gtacctaaga ctgccaagac tatcgcagtt
     3721 cttgaccgta ctaaagaacc gggcgctaac ggcgaacctc tttaccttga cgttaaagac
     3781 tgcttctacg gcgcagaaaa tgctccggtt atcgttggcg gtcgctacgg tttgggttca
     3841 aaagatacta ctcctgctca aattctttca gtattcgaaa acttggccat gccaatgccg
     3901 aagaatcact tcactatcgg tatcgtagac gacgttactt tcacttctct tcctcaaaaa
     3961 gaagaaatcg ctttaggcgg tgaaggaatg ttcgaagcta aattctacgg tttgggtgct
     4021 gacggtacag taggtgctaa caagaactct gtaaagatta tcggtgacaa cactgacaaa
     4081 cactgccagg cttacttctc ttatgactct aagaagtcag gtggtttcac ttgttctcac
     4141 ttgcgtttcg gtgatactcc gatccgttcc acttatttgg taaatactcc gaacttcgtt
     4201 gcttgtcacg ttcaggctta cctgcacatg tacgatgtaa ctcgtggttt gcgtaagaac
     4261 ggttctttct tgctgaacac tatctgggaa ggtgaagaac tggctaagaa cctgcctaac
     4321 aaggttaaga aatattttgc acagaacaac atttccgtat actatatcaa cgcaacacag
     4381 attgcattgg aaattggttt gggtaatcgt accaacacta tccttcaatc tgcattcttc
     4441 cgtatcacag gtgttattcc tgtagaccag gctgttgaac agatgaagaa attcatcgtt
     4501 aagtcttacg gtaagaaggg tgaagacgtt gttaacaaga actatgctgc cgttgaccgt
     4561 ggtggtgaat acaagacttt agctgttgat cctgcttggg ctaacctgcc ggatgatgca
     4621 aaagctgaaa acaacgatcc tgcattcatc aacgaagtag ttcgtccgat caatgcacaa
     4681 gatggtgact tgctgcctgt atctgcattc aagggtatcg aagacggtac ttggtatcaa
     4741 ggtacttcta aatacgaaaa acgtggtgta gccgcattcg ttcctgaatg gaatccagaa
     4801 aactgtatcc agtgtaacaa gtgtgcatac gtttgtcctc acgcttctat ccgtccgttc
     4861 gtactcgatg ctgaagagca gaagggtgct aagttcgaac aattgaaagc agtaggtaaa
     4921 gtattcgacg gtatgacatt ccgtatccag gttgacgttc tcgactgtct gggttgcggt
     4981 aactgtgctg acatctgtcc gggtaatccg aagaagggtg gcaaagcatt gacaatgaaa
     5041 cacctcgaaa gccaattggc tgaagctgac aactggactt actgtgctga aaacgtgaag
     5101 actaaacaac atcttgttga tatcaagtct aacgtgaaga actcacagtt cgctactccg
     5161 ttgtttgagt tctctggtgc ttgctctggt tgtggtgaaa ctccgtatgt gaaattgatt
     5221 tctcaattgt tcggtgaccg tgaaatggtt gctaacgcta ccggatgttc ttctatctac
     5281 tctggttcag ttccttctac tccgtatact acgaacgaaa acggtcacgg tcctgcttgg
     5341 gctaactcac tgttcgaaga cttctgtgaa ttcggtttgg gtatggaatt ggctaatgaa
     5401 aagatgcgtg ctcgtatcgt gaagttattc aacgaaatcc ttgctgccga caacgcttca
     5461 cctgaagcaa aagaagtgct gaaagcatgg attgaaaaca tgtacgatgc tgacaagact
     5521 aaagaattgg ctcctcaagt gaaagcagtg attgaagaag gtctttctca cggatgtcct
     5581 atttgcaaag aactgaaagg actgactcaa tatcttgtaa aacgcagcca atggatcatt
     5641 ggtggtgacg gtgcttctta cgatatcggt tatggtggtc ttgaccatgt aatcgcttcc
     5701 ggtaaggacg ttaacatcct cgttctggat actgaagttt actctaacac aggtggtcag
     5761 tcttctaagg ctactccggt aggtgctatc gctaagttcg ctgctgctgg taagcgcgta
     5821 cgtaagaaag acctcggtct gatggctact acttacggtt atgtatatgt tgcacagatc
     5881 gctatgggtg ctgaccaagc tcaaactctg aaagctatcc gtgaagctga agcatatccg
     5941 ggaccatctt tgattatcgc ttacgctcca tgtatcaacc acggtctgaa agcaggtatg
     6001 ggtaagagcc aggaagaaga agaaaaggct gttaagtgcg gttactggca cttgtggcgt
     6061 tacaacccgg ctctggaaga agaaggcaag aatccattcc aattggatag caaagaaccg
     6121 aactgggaag atttccaagg tttcttgaaa ggtgaagttc gttacgcttc tgtaatgaaa
     6181 caatatcctg ctgaagctga agaactattc aaagctgccg aagaaaacgc taaatggcgt
     6241 tacaacagct acaaacgttt ggctagagaa aactggggtg ctgaataata gtaataccct
     6301 ataaataaaa aacggtaatc ttgtagaaga ttaccgtttt ttattgtatg aactctgtcc
     6361 aacataaaca gtactacctt tttcccacta gagttcatgt ctattttata tttaaaatta
     6421 agaataacaa tgctccaatc tatttattct ctgacttcgg aatccaacta tccaccaaca
     6481 gccgatgctc atccctccat ttacgggcta tttcttcttc atccatcctg gcatccttca
     6541 tagctgtcat aaaagagcta agttcttctg tcgttagttt gatgttgcca aagaactcgg
     6601 cagcaaacgg atctttctca ctgaatcctt tccatgcaat agcatgtatt tcttccaagt
     6661 ctccatatac tttcttcgga tcatccaaga atttcaagtc aaactggtcg aacatccaat
     6721 gcggtgtcca ccccgtaatg acaatccatt ctcctttgtc catcgctttt ttcaaagaag
     6781 ccagcatggt ggaactactt gaagtcatga gggtataccc atcaagtccg taagcagcaa
     6841 tggccttatc ggtcgtcttc attatccctg ctcccgcatc aattcctact atttcagaag
     6901 aaaaacggtc tttattagct tccagctcat taatagactg gatcgtaaca tattgaggaa
     6961 caaccagtcc gacgcgagct tctccgtata cctcccccaa aaattcgatg ctgtctccat
     7021 actgatccat ataatctttc atcgttattg gtaaccaggc atccagaaac acatctgatt
     7081 tctttcctga catagataca aaaatagggg caagatcagc attttgcaat tcaacctcat
     7141 atccatgctc ttccaatacc accttagcca aatgactcat ggcaatacct tccagccaat
     7201 tggcataggc tatttttact ttctttttct ctaagtctga attagtacag gaagctagca
     7261 aaagcatagc cgaaagcact attcctacta ttttatatat tctcacatgc atttttattc
     7321 ctttccgttt tagttcttat tttttcgtcc tgccattcct tgtgtgatac ggtctaagat
     7381 gatagctaaa ataacaacag ctataccacc ttcaaaccca agtccgattt tcatttgggt
     7441 aatacctttc aatacaattt ctcccagacc accggcagca atcatggcag caatgacaac
     7501 catagaaagc gacatcataa ttgtctggtt gacacctgtc agaatggtgg gcaacgccaa
     7561 aggaagctgc actttataca ataactgcca acgggtagcc ccgaacgaac gggaagcttc
     7621 cactacattt ttaggaactt gccgaattcc caatccggta aggcggacta caggaggcat
     7681 agcaaagata atggtagcaa acactcccgg cactgctccc aatccgaaaa acaaaacagc
     7741 aggaatcaga taaacaaaag caggcatcgt ctgcatcaag tcgagaacag gacgaagtat
     7801 tttctctgca cgcggactgt ttgccgtcca cactcctaaa ggtacaccaa caatcagagc
     7861 cagacaggta gatgaaaaaa cgagagccag ggtttgcata gtagcctccc agaatcccat
     7921 tccatagatc agtaataatc ccaatgcggt gaaaattgcc gtaccgcgtc ctgctttcat
     7981 ccatgcgagt gtagcaagta ccaaaatggt tatataaaaa ggtattccga aaagtatgtg
     8041 ttggaatcct ataataaaac taccgatgcc cgcattcacg gcatcaaaga aagtggaaaa
     8101 atgtaccatc atccaattga tggccatctc tatatattgt cctatattta tcataaatct
     8161 attgcgtttt gaattatttc gtttatttct tctttgtctt tcccggtcac ttcgatgatt
     8221 aaggatgaaa gcgggattgt tcctaaaaac tcgcgcgtct catcaatcac ccataccggc
     8281 gaattgctct ttgtcattag aggaagtata tcctccaaca ccgtatcctc caacacagaa
     8341 tgtacttctg tacgcacaat cgtttcaatg gatttttcct gtttgctacg taacttaagc
     8401 aagtcgttca gacgtacttc tccgaccagt ttatcatcgg cgtctatgac aggtaatacg
     8461 gtgatattct tcgcacgcat cttacgaatc aatacttcgg gaccttcttt cttcagacgg
     8521 gccaccaacg gtttgtcaat cattaaagaa gaggcggtaa taattttgct cctatccacg
     8581 ttttcaacaa aacgggctac ataatcgtta gccggttcag tcaggatttc ctccgaagta
     8641 cctacctgca ccacttctcc gtctttcatg atggcaatac ggtcacctag cttaattgct
     8701 tcactcaagt cgtgggtaat aaaaacaatc gtctttttca tctttgattg caaggccagt
     8761 agttcatcct gcatctgtac gcgaatcaga ggatcgagag cagagaaagc ctcatccatt
     8821 aaaagcactt caggattatt agccagagca cgagccagtc cgacacgctg ttgcattcca
     8881 ccggaaagat cgcctaccat ctgattttca tatcctttca atccgacaag cttcatgctt
     8941 tccatcgctt tcttctcacg ttcctctttc ttcactccct gaagttcgag gccgaacgcg
     9001 atattgctca atacggaacg gtgaggtaac agaccgaaat tctggaaaac catcgccagc
     9061 tctttccggc gaacctgcaa taattctttt tcggaaattt tagatatatc tactccgttt
     9121 acaagcactt gtccggcagt aggacgtatc agacgattga tacaacgcag taatgtcgat
     9181 tttccacttc ccgagagtcc cattatcacg aaaaactctc cttcattaat tgaaagattg
     9241 gcatctttca ctcctaccgt acaaccggta tctttcagaa tttcctcttt actcttatct
     9301 tttttcaaca tcttgagggc tttctgcttc tcgttaccaa agataaggta caaatccttt
     9361 atttctattt tactcatata atatattggt ttagattata atatttgttt tgttttcaac
     9421 tgccgcattc cttattctca cttacgataa acaagttgaa tgttcgcatg gttcagtcat
     9481 gccacatgat aacatgacgg tccgacgttt tttaaatggt taaaaaaaac agacagagta
     9541 gtttaaaagg aatagaattt gataagatta tcctcttaat gaacagtaga aaatagtatt
     9601 ttcataaata aataacagtc tgttcttgca tattgttggc acaaaggtaa ggaaaataga
     9661 ttaaatatgc aaatttcatt caggtacgga gtaattccaa agatgctttt tcaagtctac
     9721 gcatccattt tgtttgaaag agatcccttc ttccaacaag agttgtttct gctctgtcca
     9781 acccggaaca agccgtcccg acgcattgac aacccgatga caaggcgcag ataaatcatc
     9841 cggaatctgt ttcaaagcac gccccaccat acgggaacat tgagacattc ccaataatgc
     9901 ggcaattccc ccataggtag aaactttacc taccggaatt tctcggacaa cctgatacac
     9961 ctcttgacaa aaggatgcgg aaaggctcgc cttatctact ttataatctt tcatcactca
    10021 aacattactt tatttcagtt ccaaaactag ataaaaagaa aagaatttgc aaataataaa
    10081 agcatttcaa ataaaatatg caactttatt tgctttattt acaaataatc ccgacctttg
    10141 tccccaataa aagcaaccct attattaaca aaacaagcac tgctgttatg aaaaagaaaa
    10201 ctatcctgtt cgcttcttgt ttattgggag cactggcttt cagctcctgt gagaagaacc
    10261 tttatgatga aagtaaacaa cccgagaaag aaaagagaat aacagacttg aatattcctg
    10321 ctgactttga ttggaaaggt tctcaaaatg ccaaagtgaa aattgccagt caatcaactg
    10381 ctactatttc tgtatttcta gaagaaaatt gcaatgaaga ggctttgatg cttcgaatgg
    10441 atgtcgatgc caacatatca aaattggaac tcccaattga aattcctgca tatataaaaa
    10501 atgtgtatgt aaaatatggt aatggctctg aaatacaaac tgttcctgtt gaaagtaatg
    10561 gtactatttc tatagtagta cctgctaacg ctacggcatt atccagagtt accacaagag
    10621 ctaataaaga agttgaaacg aacaacatct tcaattatcc gggatatggc aacggaacta
    10681 ttatgttcga agatatgtat ccagctttag gcgattatga ttttaatgat tttgttgcat
    10741 ggtataattt ccaaattgac ggtttttatt ggagtcacaa tcaatgttat gcagaatact
    10801 taatgatagg attccaaatc agagctatag gaggtatata tgactacaat ccttatatcc
    10861 gcttggcaga agtacaatat aatgaacttg atttagaaga aactcaaatg tatcttgagc
    10921 gtaacaatcc tgaagaggct gaaaatatca aaatcctaaa aggcccaaaa ggggaattga
    10981 ttatttcact aaagaaaccg gccattccta acggatacaa gtattataat acggaggtaa
    11041 atgaaaaaac aaagcctaaa aaaatgatgg ccatttactt ggtgttcaac tcacctgtta
    11101 acgttaaaag cctacaagac agtaaaatgg acttttatat tgcaaaaact aataaaggac
    11161 aagaaatcca cttaaaaggt tatagcccgg tttattataa cagcaacgaa agttatgtaa
    11221 atgaagacaa ctttatatgg ggattaaaag tacctgcatc tttacatcat gccagagaag
    11281 aagtaaactt cttggaagca tatccagact ttgaacaatg ggtaacatcg ggaggtcaaa
    11341 agaaccaaag atggtggaat aagccaaaaa cgaataagtt gattatgaat taataaatat
    11401 acagtaaatc atatactgaa ttaaataaga ggtaaggtat gtcaatagat ttccttacct
    11461 cttattttta tcatatgaat tccatagaag tataaacaga taaatgctca ccatcaaatt
    11521 ttgcagattc tatcctatcc tttcctcttc aacaaatctg tcggactctc tccaaactgt
    11581 tctctataac atttagtaaa ataagaagga gaactaaaac caacttcata acctatctct
    11641 gccactgtca tatccgacga ggcaagcaga gaagcagctt tcttcaaacg agctatacga
    11701 agcagttcat tcggagaata attagtcaga gatttaatct tgcggtaaag ttgcacacga
    11761 cttaatccca tatccttacc caaatcttct acattcaaat ttgaatctcc catctttgcc
    11821 tcaatcagag ctttgaattt ttccacaaag tctttatcca tatcacagac atcctctttc
    11881 gccaacgttt gtccgtcacc aaaaaactgt ttcaggcggc ggtgtgaatc tatcagatta
    11941 cgaacgcgtg ccaatagtaa ttgcgaactg aaaggcttgg agatataaga atctgcacca
    12001 ccatcatacc cttgaattcg ttgttcatcc aaagaacaag ctgtcaatag gataacagga
    12061 atatgacagg tttgtaattc gcttttcaag cgacgacaac attcaattcc atccattccg
    12121 ggcatcatta catcggagat aatcaagtcc gggacatatt tcatagcttt acgaatacct
    12181 tccgagccgt ctgcagcttc tataacagta taatcagtgt gaagcaatcc atgcacatat
    12241 aagcgaatat cagcgttatc atcaataatc agaacgcaag gtttggaaga gtcgtaactt
    12301 ttttccaatt cctcttcttc gtaagttaaa gcatcattca agctcgaaga accggaataa
    12361 ccagaagttg caggagttac gggagcccca gcaacggcag aggttgcagc atcggtggag
    12421 gttacagaag tagcagggac agagaatgcc ggagagtttt cagaaacaac agtctcgcaa
    12481 gtctgtacag gcaaatcaac ggtaaagata gttccttgct tttcatcact ttccactgtg
    12541 atggtacctt tatgcaattc cacaaaagcc tttaccaatg ccagtccaat acccgaaccg
    12601 gcatggtgca tatctatctt atagaaacgg tcgaaaatat tccggatatg ctccgcagaa
    12661 atcattgagc cggtattggc aacagtaaag cgaatccaac aatgatcgtc tttagtcagg
    12721 gaagataagc gtacagttac ttttccattc tccggagtaa atttgaaagc gttggaaagg
    12781 aggttgaaat agatgcgttc caacttttct acatctgcca atgtgcggta atccgtatcc
    12841 ggcatataat cgaatgagaa atgaatatgt ttcttccggg ctgctgccat gaaagactcg
    12901 ttccatccct caaaagaaga aagaatgtct aacgaaatag gagtatattc catttttcca
    12961 ttctcgtatt tacgaaaatc cagaatctga ttgacaagac gcaagaggat attcacgttt
    13021 cgctgaacta acaataacat tcggcgctga tcttcactca aagacgaatc agccagtaaa
    13081 tgctctaccg ggtcggcaac taatgtcagt ggagtacgaa aatcgtgaga tatatttgtg
    13141 aagaaaacca gcttggcatg agtcgcttct tccagttgat gagaaagctg gataagctga
    13201 tcccgctgtt cttcgagttt gtcacgctgt tcttcaagaa tatcccgttg ctcttcgagt
    13261 ttatcgcgct gttgctctac ttgtttcttc tgttcggaca actctttatt caggcgattc
    13321 ttggaacgga gggatttata gactaccaac aacaatcccg ctactaataa aagaataacc
    13381 aagccgccat acatcacgac ctgctgcgta gctacacgcg acagataccc accgatacgt
    13441 ccgttcaatg tttcaatctt ctgatccagt tccgagatat gggtagtctg aagttgcata
    13501 acgtgcgcgt tcgtgcggtc tacaacggca gtattcatga ccgtttcgcg aggataagac
    13561 ttcttctcaa gaatattcat ggccagttgc atcactttgt ccccattagt cggataaata
    13621 aaagttgcat cgagcacatt gtcaagcacc aattcaagcc cgtttccttt gccgggcagg
    13681 gcatcaatgc caacaaaaat catttccttt tcacgtccgg ctttcttcgc agcctgatag
    13741 gctcccggag cgatacggtc gttatgtgca tacaccgcat caatcttcgg atgacggtga
    13801 agcatactat ccatttccac ttctgccggt tcacgttccc aggcagcatc cgctttatca
    13861 atcagtttga tatccggata attgctgata gcggccataa atccctgatg gcgctccata
    13921 gcaggggtgg aaccacccag tccggtaagc tccactacat tccctttccc tttcagactt
    13981 gatgcgatat aatttcctac cgcacgacct atttcataat tatcggcacc aatataggca
    14041 gtatatttat cagaaagtat cttccggtct acaagaatga caggtattcc tttctgatag
    14101 gcctcctcca caattggagt catgggagcc gcttcattgg cggaaattat cagtaaatca
    14161 actcctttat ctataaaata atgaacatct tccgcctgct tacggttatc atccgccgcc
    14221 gaacggattt caaccgacac tccatcataa aacatcgctt cgcgaagaat ctcatcattc
    14281 atcttgtgcc tccaagagtc atcgctacat tgggccaccc caatacggaa acgaggcgca
    14341 tcctgccgac aggccgccaa gcccaaaaga caaagcaaga ctgttatcca cttcgtatat
    14401 ttcatcgctt caatcattcc ctttctttcg tatatctttt gtatttcttt ctgtaatcca
    14461 aatttctctc cccgcattat ttgcattcac caccgggaaa tacatcagtt ccactttcac
    14521 agggttcagc gtatattttc cagtaaagcg tggaagcaaa ggaaccgtaa actgataagt
    14581 acctaccggt aatttttcgc taaagataac agttttctct ttaaaatact cacgatatac
    14641 ttcagaacgg gagaaattaa caggttttga ggcataacta caacctgccg gaacaggaac
    14701 ttcgagcatc acatattgcg caccctcctg tttcacctgc aaggtaactg tcaatgtaac
    14761 aggtacaccc gccaccaaag agtctttttc caaagtcacc tccaccttga aagcatcact
    14821 ctgacgagca ttcatcacac gcttcattga atagacacta tacaataaag gctcttttcc
    14881 cgtttttgaa ataagcagac tgtcgcctgc tgtcagccgg gcatgataag gaaattccgt
    14941 aattcgttga tgatccttac cgctcacaga caccgacgtt cctgacatcc ctccggaacc
    15001 tgccagcaaa tcggtcagaa cagttgccac agccgaagaa gcctgatacg tattccatcc
    15061 gcgctcctta gtccgcaaaa tatacaattg catattttct ttcaacttac acagggaagg
    15121 gtcattttta ataatccggt aggctatcaa tgtatttatc atctgatttc cctcccaata
    15181 ataagtacgc cgtccgtcgt cacagtaaac accttccagc atatcctttt tcagataagg
    15241 acgtacgcta tcacccacat tcaccgaatc cacctgttgc ttgatttccc agagaagcag
    15301 cttctctttc aagtatgaaa gaggacgata atacttgttt ctatttgcca acgagtcttc
    15361 tttctgttcc aattgccgga cgaaaggttc caataatctg actgccgaag aataatccgc
    15421 ctctactttc cactcatgca gagcatgaag tatttctata tcttccagtt tcattcctcg
    15481 ataaggacgc gtatgagcat actccacttt caaaccattc agattcaact ccacaggata
    15541 acctgcatct tgcgccatct tcaaagcccg cagaatatgc gcagacatcc agaaagaagt
    15601 attttcagag ttcccccacc acgaccataa ctgatgtttg ttctgatgat tcgtcagtcg
    15661 atggatgata ggtcgaattg ctttatctac tttcaccttt tcacccttac tctgcatata
    15721 ctgttggtaa gccaacaaac cggttaactt ggatgccagc tgctcattgc acaaatattt
    15781 gtatcctgtc aagtaattca ctgattcttt atagatgtcc aactgattgt cagtgatact
    15841 caccatcact tcttcatcct cgccggattg cactttgacc gtctttgcat cggacagaat
    15901 acccaatgtg ccctccgcca attcagttcc ctgtggcagt atcggaatcg tatattcctc
    15961 tccatcctga tagccatcgt cgcgagtgaa aagatagctg atggtcacgc tatcggcatg
    16021 aactgcctgc atcggcactg tttcatgaaa tccctccatg aaactcactt cctgccgttt
    16081 caacgtatcc gttccgacgc agaactgtgt ctttccggct atgtgctgcc catccagata
    16141 attgcggata gtcccgacca ccgtactctg atccccctcc accaagaagc ggggagtttt
    16201 caactccgcc atcaacggtt tgtaagagcg gacgaaacgt cggaaagtac ccgtctgcaa
    16261 acgacggttc atgccataaa cgacagtt
//
