LOCUS       gnlProkkaJAIPKOPJ_7     9242 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JAIPKOPJ_7.
ACCESSION   gnlProkkaJAIPKOPJ_7
VERSION     gnlProkkaJAIPKOPJ_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 01:31:55
            Original ID  :: gnl|Prokka|JAIPKOPJ_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 46331
            Orig. end    :: 55573
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9242
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:9241]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9241
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9242
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9242
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(217..1050)
                     /locus_tag="ctg7_41"
                     /transl_table=11
                     /translation="MAIAYDGINYFPVGVNFMEENAMEVIEAKYGIKGSAIVLKLLCKI
                     YKEGYFIRWDEEQCLIFANKAGREVQAAEVQGIIEILFIKGILDRNSYLANGILTSANI
                     QKIWMEATKRRKRDLKALPYLLVNDLTQQETEAPEGENVTISPGNVVHDVTVNAKNACN
                     SGQSKVKEKKAEENKELPPSAPPKGKEKEWEEVSAPLPIPGYAFNTMTHNYPGLTDTLK
                     RLGITEAGEVNAILRLSDYGRKGTRVWQLIANTCWSDIGVKGRYLIAALNKAKRK"
     CDS             complement(1189..1536)
                     /locus_tag="ctg7_42"
                     /transl_table=11
                     /translation="MKQKKRPASQTEAMKLRWKKRIVFEKGYTEQCAEWMAERLEALTD
                     HLQYGHAAIAYQKQNGDFRLVKATLIYYETEFHKKYDPTQIEGAVVYWNVDEQRWTTFQ
                     MENFMEWRPIV"
     CDS             2732..3163
                     /locus_tag="ctg7_43"
                     /transl_table=11
                     /translation="MRYEYVFRGERKIRKLVPVVHNLVFVYATRSEVDEMKSTVGASLP
                     IRYIMDRETRQPITIPEVQMRSFIAVAGNYDEQVVYLDPSVVSMKKGDRVRVTGGIFEG
                     VEGEFVRIKGDRRVVVSIQGVMAVATAFIHPSLIELIKN"
     CDS             3222..3707
                     /locus_tag="ctg7_44"
                     /transl_table=11
                     /translation="MLSLQSEIDSLCAVSHELLHLGLDGEPIYSDRFRQLNTDVYHRCE
                     HLFGSHGRTLEEEASLCIALLTGYNATIYNHGDKEDKIQSVLNRSWDLLDTLPVSLLKC
                     RLLVACYAEVFDEELAAEAHAIIDGWKDRELTREECEIVEHLKSLEANPYPYSELHE"
     CDS             3704..4987
                     /locus_tag="ctg7_45"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMLFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             5001..5699
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_46"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.3e-13, bitscore:
                     43.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILPLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNSLEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             5719..7020
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_47"
                     /sec_met_domain="CTP_transf_like (E-value: 1.2e-12,
                     bitscore: 39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.5e-122, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.3e-64, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             7032..8168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 71.8;
                     E-value: 7.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_48"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.4e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-20, bitscore:
                     64.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGVALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             8165..9241
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 5.9e-34.
                     Score: 109.4. Matches aSDomain:
                     nrpspksdomains_ctg7_49_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.6; E-value:
                     1.8e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_49"
                     /sec_met_domain="Aminotran_5 (E-value: 3.6e-31, bitscore:
                     100.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVM"
     aSDomain        8255..9043
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg7_49_Aminotran_5.1"
                     /evalue="5.90E-34"
                     /label="ctg7_49_Aminotran_5.1"
                     /locus_tag="ctg7_49"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
ORIGIN
        1 tttgcattta aagaatttgc tatttgcaga cgaaaaacga actttaacgt aacgttaaaa
       61 taaagcttct gcagattgaa atattgtgct ctgaagtggc tgtagatcat ttgtttaaat
      121 gtacgtcccg ttttccattc ccgacagaga accttccgga tggaaaccgg tatacttgct
      181 tttttatcaa ctgcaaactg tactttccta tccggattat tttctttttg ccttattcag
      241 tgctgctatc agataccttc cttttacccc tatgtcactc cagcaagtat tggcaatcag
      301 ttgccatacc cgtgttcctt tccttccata atccgatagc ctgagtatgg cattcacctc
      361 tcctgcttcg gtaatcccca gtcttttgag tgtatccgtc agtcccggat aattgtgtgt
      421 cattgtgttg aaggcgtatc cgggtatcgg gagaggagca gaaacctcct cccattcttt
      481 ttccttcccc ttggggggag ctgagggggg taattcttta ttttcctctg ctttcttttc
      541 ttttacttta ctttgtccgg aattgcatgc attttttgcg ttaacggtta catcatgtac
      601 tacatttccc gggctaatgg ttacattttc accttccggc gcttctgttt cctgctgagt
      661 caagtcgttc accagcagat agggcaatgc tttcagatcc ctttttcttc gctttgttgc
      721 ctccatccat atcttctgta tgtttgccga agtcagtatt ccgtttgcca gataactgtt
      781 tctgtccaat atccctttga tgaagaggat ctcaatgatc ccctgtacct cagcggcctg
      841 cacctctctt cccgccttgt tggcaaaaat cagacactgc tcttcatccc aacggatgaa
      901 gtatccctct ttgtatattt tgcacagcag tttcagtacg attgccgaac cctttattcc
      961 atatttagct tctatcactt ccattgcgtt ctcttccatg aagtttacgc ccaccgggaa
     1021 atagttgatc ccgtcatatg ctattgccat tgttttttag attagtcgtt tgtactttca
     1081 ataatacatt caccataaat taccccggat tcccaaagat gtcttcactt gatttctcaa
     1141 aataaaaata attcatcggt gaaaatccgt gtaatctgtg gtggcgccct atacgatcgg
     1201 tctccactcc atgaagttct ccatctggaa tgtcgtccat cgctgttcat ccacattcca
     1261 gtagactact gcgccttcta tttgtgtggg atcatacttt ttgtggaatt ccgtttcata
     1321 gtagatcagt gtcgctttta ccaacctgaa gtctccgttc tgcttctgat aagcgatggc
     1381 tgcgtgcccg tattgcaggt ggtcggttaa cgcttccagg cgttccgcca tccattccgc
     1441 acactgttca gtatatcctt tttcaaagac aatccgtttt ttccatctca gtttcatggc
     1501 ttcagtttgt gatgccggtc ttttcttctg tttcatacgt atatgattta aaaggttaat
     1561 agataaatta tcgccccaaa gataggtcag atcgaatgta ttccggtttg ataaaattca
     1621 ttgtacgtat ttcagcgctt tccttcttgg ttctttttct ttctttccat cttattccag
     1681 atctcgttga cgtaagttct gattgtgctg aaaactaatg gtttgaatac tccatttctt
     1741 atttttccaa aaagtttttt ttcctctatg tagcgtgcca atgaatcttt gcacgtcttg
     1801 atattttgtt cttttgcgtc caatatgtag gattctatca gcgcttttat aactccttca
     1861 ttgttggaga taattcccgg tatctgcgtt cctgcttttc tgcctcttgt ttctttaatg
     1921 gcttctgtga taggaggttg tgctttagtg ttatcgtttt tttacacttt tgttcactgt
     1981 ctgtaataat tcattttctt tgttcatgat ttttttattt aatcaataac taaatgttgt
     2041 taatatgttg caaaggtaga gagtaatctt tcagtgagca aatgaatgtg gaattaaagg
     2101 ggaaataaaa gggaaaatga aaccttttct cttcttaatt gtctgacatt aaatgaaata
     2161 attcttaaaa aagtgagtgt ttcaataaac gatcgtctaa ttaaacgcaa agatagaggg
     2221 tattttcata actgcaaaat gtttaataaa aaaaatattt tttctcttgg cttgttctgt
     2281 ttaactatct ggtaatcaaa tgtctataaa ctaacaaaaa acgctttaat atctgtctgc
     2341 ttttatatgt attttaattg tctggatctt taaaaaagtg tgtttcaaaa gacgatcgtc
     2401 ttttgaaaca ctttcgcttc ataatagact cgtttacaga ttgtaagatc agtaaggccc
     2461 tgttttttca aaactttgtt ttctgttctt ctttttcaaa ctgtctctcc tgcgataggg
     2521 gagtacctga tgaaatgata tacgctgcaa ggcaaacaac agaattagca aacttgaccg
     2581 gaaggtgttt cactaccccg gtgtccccca attatatcct tttgtgaaca atagcattaa
     2641 taaatcctgg tacgcccttc gtatcaccta tagccgtgag cttgccttta aggaatatct
     2701 ggactcccgc ggagtgagga attttcttcc catgcgctat gaatacgtat tccgtggtga
     2761 gcgtaagatc cgtaaattgg ttcctgttgt tcacaacttg gtttttgttt atgccactcg
     2821 cagtgaggtt gacgaaatga aatccactgt cggggcttct cttcctattc gttatatcat
     2881 ggaccgtgag acccgtcagc ccattaccat tcctgaagtc caaatgcgta gttttatcgc
     2941 cgttgccggt aattacgatg aacaggttgt ttatctggat ccttcagtcg tttccatgaa
     3001 aaagggagac cgtgtccgtg tcaccggtgg catcttcgag ggagttgagg gtgagtttgt
     3061 ccgtatcaaa ggtgaccgcc gtgtggtggt ttccatccag ggggttatgg cagttgccac
     3121 ggccttcatt catccctctt taatcgaatt aataaagaat taaaaactct gtgaactctg
     3181 tgccctctgt ggtgcatatt ccaatacgta aataaatcac catgttgtct ttgcaatcag
     3241 aaatcgattc tttgtgcgcc gtttcgcacg aacttctcca tttaggtctg gatggcgaac
     3301 ccatctactc cgaccgtttc cgtcagttga atacggatgt gtatcatcgt tgtgagcatc
     3361 ttttcggttc acatggacgt accctcgaag aggaagcttc tctttgtatc gctttgttga
     3421 ccggctataa tgctaccatt tataatcacg gtgataagga agataaaatc cagtcggtcc
     3481 tcaatcgtag ttgggatctc ttggatacac ttcccgtctc tctgctgaaa tgtcgtttgt
     3541 tggtagcttg ttacgccgag gtctttgacg aagagctggc ggcggaggca catgcaataa
     3601 tagacggttg gaaggatcgg gaattgacga gggaagagtg tgagattgtg gagcatttaa
     3661 agagcttgga agctaatcca tatccgtaca gcgaactaca cgaatgattc gttcctttct
     3721 ttcccgttct cccctttacg ttttggctct ctatgccagc gttttgattt ttctggttta
     3781 tacttgtgcc tatgcctacc gtaagccatt taccgcagcc atttatgaag gtgagattct
     3841 ttggggattc gatgtcaaaa ttctgtatgt cctttctgag attatcggct acgccctttc
     3901 caagttcatc ggtgttcgta ttttgccttc gatgaaagcg ggtcaccgca tctattatat
     3961 aatagggctg cttacttttt ccgaagttgc tttgttgggt tttgcacttc ttccggttcc
     4021 tttgaaggtg tgttctattt ttctgagcgg tcttcccctg ggtatgatct ggggtgtcat
     4081 ttttagctat atcgaagggc gtcgtatcag tgaaatattg aatgtcgggc tgagcgttgc
     4141 tttgatagtc tcttccggtt tggtgaaaac cttgggacaa ttcgtgatgg ataatttgca
     4201 tgtgtcggaa tattggatgc tttttaccac aggtttgttg gtataccctg ttatgttgct
     4261 ttgcagctgg cttctcaatc agattccggc tcccaatgag caagatatca tacagcgtac
     4321 caaacgtgct ccgatggatg gtaaagacag gcgtaaattt ttgaggcaat tcttctgggg
     4381 aatctgcatg ctggttgttt tttacggtgc cctgaccgtg ttccgtgagc ttcgtgactc
     4441 tttcgctgcc gatatttgga aggagctcca tattgagggt gcaatgatct ttactcagac
     4501 agaggttccc attgccgttt ttgtccttgt actgatgttc ctgattgtgt ttgtccgtaa
     4561 taaccgtttg gctcttaata tcatttattg cattgccgtc acaggcggtt ccttaatggt
     4621 tttttccaca ttgctttatg tgtacggttt tctttctcct atttggtgga tgattctttc
     4681 cggtcttggt ctgtatatgg ggtatattcc tttcacttac ctgatagaac gtctgattgc
     4741 ttcccttagg gtggttagta cggctgtttt tattatttat ttggccgatt ctttcggcta
     4801 tctgggcact acgggtgtgt ttatggtcaa gaacttcgtt tctgctgaca tttcctggac
     4861 tgtcatgcta atgcgtactg cccttttttc aggatttgtt tctgtcctgt cgatttttgc
     4921 gatttactgt tatttcaagc aacaattgaa ttcacttata ttaattccct ctgaaattca
     4981 tgattaaaac agcaatgatc atggctgccg gtcttggtac ccgcttcggg cattataccg
     5041 agcttgtgcc caaaggtttt gtggaggttg gtggaaaacc tatgattatc cgctctatcg
     5101 aaacccttct ttcctgcggt atcgaacgta tcatcctcgg tacgggttat aaaaaagagg
     5161 cttatgaagc ccttcaggcg gatttccccc agatagagac ctgtttcagt ccccgttatg
     5221 ccgatactaa cagtatgtac actctgtaca atacgcgtga cgtgataggc gatgacagtt
     5281 tcctgctgct tgaatcggac cttgtttttg aacgcaaggc catcctcccg ctactggatg
     5341 acgaattccc ggatgtgatg cttgtctctt ctctgaccaa gttccaggat cagtattatg
     5401 tggaatatga ccgcaatcac atccttactt cctgttcggt agacaagaac tcccttgagg
     5461 caaaaggcga gctggtcggt atccataaac tttccaatac tttctaccgc cggatgtgcg
     5521 ccgattatgc gaccatcctg gagtcccagc ctaaactggg ttacgagtac gaactgctcc
     5581 gcatgtcccg ttccgtttct cctgtccgtg tgctcagggt ggagggtctt aaatggtatg
     5641 aaatcgatga tgaagccgac ctttcgtatg ccgaggagca catcatccgc tattgttaaa
     5701 aacaaatctt ttccatatat gaacaagaaa atctatgtcg gtatgaccgc ggatatcatg
     5761 catccggggc tgatccatat tattcatgaa gctactaaat acggtgatgt catcgtcggt
     5821 ctgctgacgg acaaggccat cgccgaacac aaacgcctcc cttaccttac ctatgatcag
     5881 cgtaaggagg ttgttgagaa tatcaagggg gtttgcgaag ttgttcccca ggaggactgg
     5941 agctatgttc cgaatctgga aaaactcaag cctgactata tcatccacgg cgacgactgg
     6001 aaaacgggcc cgttgcgcga ggtgcgcgaa caggtttttg aggtgatgaa cgcccagggg
     6061 ggcaaggtaa tcgagatccc ttatacccgg ggcatcaact cctcctcgct cgacaaggat
     6121 atcaaggcga tcgggactac ccctgacgta cgtcttaagt ccctccgccg cctgatccag
     6181 gccaagcctg tggtccgtat cctggaggct cacgacggtc tttgcggtct gattattgag
     6241 aatcttgaag tccagaaggg tgataagcgc gaggtctttg acggcatgtg gtccagcagc
     6301 ctgaccgact ccacgagtaa gggtaaaccg gatattgaag cggtcgacct taccacccgt
     6361 ttacaggacc tgaacaatat ccttgaatgc accaccaagc ctattatttt tgatggagac
     6421 acgggtggca agatcgaaca ctttgtcttt actgtgcgca ctctggaacg tcacggcatt
     6481 tctgcggtaa tcattgaaga taaagtcggt ctgaagaaga attccctttt tggtactgac
     6541 gctatccaga ctcaggatag tatcgagggt ttctgcgata agatcagagc agggaagaat
     6601 gcccaggtca ccggtgactt tatgatcatt gcgcgtatcg aaagccttat tgccggcaaa
     6661 cccatgagtg acgccctcga acgtgcttat gcctatgtac aggcgggtgc ggacggcatc
     6721 atgatccaca gcaaggataa gtcgggtgag gatatccgtg agttctgccg gactttccgc
     6781 aaagaatacg cccatgttcc cattgtcgtt gttccgacga cttatgacca tgtgcacgaa
     6841 tccgaacttc acgaatgggg tgccaacgta gtcatttacg ccaaccacct tctccgtgcc
     6901 gcttacccgg ccatgatgaa cgtggccagg accatccttg aaaacgagcg cgccgaggag
     6961 gtccgtccgc tttgtatgcc tatcaaggaa attctggaat tgattccggg cactaaataa
     7021 atcagacggt tatggtaagt gtagaaaaga tatacgatac gttccttcat cacggtgtgg
     7081 acttctttac gggtgttccc gattcccttt tgaagaatat ttgcgcctat atcacggatc
     7141 atgctccgcg tggtaagcat atcatcgccg ccaatgaagg ttccgcggtg ggcattgcct
     7201 gcggttatta tatggcttct ggcaacgttc ctttggttta tatgcagaac tccggtctgg
     7261 gaaatacggt gaatcccctc ttgtcccttg cggacgagaa agtgtacagc cttcctcttc
     7321 ttttgctggt cggctggcgc ggtgagcccg gcacgaaaga cgaaccccag cataagaagc
     7381 agggcgaggt tacccttgat cttctgaaag ccatgaaaat tccttttata attctggata
     7441 cggatgaaga cgaggccctg gcgcagatcc atgacgcggt tgtctcggcg aagagccggt
     7501 cgattcccca tgcgattgtc atccgtaaag atacgtttgg aaaatataaa ttgcgtcagg
     7561 aagccttgaa tgactatcct ctgtcccgcg aggaggcgct aatgcaggtt gtcgaccacc
     7621 tcggggacaa tgacattgtg gtttccacca cgggcaagct ctcccgtgag cttttcgagt
     7681 accgtgaatc gaaagggcag gggcacgcaa gggatttcct aactgtgggt tccatggggc
     7741 acagttcttc cattgccctg ggggttgccc ttgagaagcc tgaccgccgt gtctactgtc
     7801 ttgacggtga cggtgccttt atcatgcaca tgggtgctgt cagcaatatc ggcgatcttt
     7861 ctcccaagaa ttacaggcac gtccttttca acaacggtgc ccatgaatct gtcggcggtc
     7921 aacccacgct cggtttccgt ctggatatcg cctcgatagc gaaaggttgc ggttatgcgc
     7981 atgtactgac tgcctccgac aaggaagggc tttcgtgtgc gcttgagaag ctgtccggcc
     8041 tgtccggccc ggttcttctt gaaattaagg tccggatcga ttcacgtgat gatctgggtc
     8101 gccctacgac tactccggta gagaataaag agcattttat ggcattttta aaagatacgc
     8161 attcatgaat atcgaaagaa agatcctttt gaatccgggt cccgccacca cgacggatac
     8221 ggtaaagctg gcgcaggttg ttcccgatat ctgtccgcgt gagaaagagt ttgcgggtat
     8281 gatgaaacag ttacgtgacg acctggtccg cgttgcgcat ggagacctct ccaaacatac
     8341 ggccgtcctg ttttgcggct cgggtacgat caatatcgat atctgcctga actctcttct
     8401 tcctgcggat aagaaagttc tggttgtcaa taacggtgcc tatagcaccc gtgcggtgga
     8461 agtctgcgaa tattacggtc ttccccatat cgatttgaag ttttccgttt acgaacttcc
     8521 cgacctgtcg gtaatcgaaa agacgctttc cgacaatccg gacatcgctt tggtctatac
     8581 cacgcaccat gaaacgggta cgggtatctt gaaccccatc cgtgagatcg gaaaaatagc
     8641 ccattcgcac ggtgccgttt ttgttgtcga caccacttcc tccctgggta tgattccttt
     8701 tgatatcggg aaggataatg ttgacttttg tatggcttcg gctcagaaag gccttcaggc
     8761 catgacgggt ctttccttta tcataggtga tgaatccctg atacgtgctt caagggatta
     8821 tccgaaacgc tcctactatt gtaacctcta tttacaatac gattactttg agaagacggg
     8881 tgagatgcat tttactcctc ctgttcaaac cgtttacgct gcccgtcagg ctcttgatga
     8941 atattttgca gtaggtgaag aggctaaatt cgcccgtcac aagagggtct ttgaagccat
     9001 ccataaaggt ttgcaagagc ttggtcttca gtatgcgatc aaacgtgaat ggcagtcggg
     9061 tcttgttgtt tctgtattgt atcctgatga tcccctctgg gattttgata aggttcatga
     9121 ttactgctat gaacgtggct ttacgatcta cccgggtaag atttccacaa cgaatacatt
     9181 ccggctttgt gcgttgggag agattgatgt ggaggatatt gagaggttct ttgaggtgat
     9241 ga
//
