LOCUS       c00044_gnlPro..         4577 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FCHHMFKJ_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:16:38
            Original ID  :: gnl|Prokka|FCHHMFKJ_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4577
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..354
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="RHYRRRKTELLNLLISTLIKNKMTTVFSDKGGFPYDTVTGADNLV
                     IITKVLDNGTSLELYDTETQKFKQLKYLEFDDKNSIGETIRKVSIDKSTKNNLSFGFGL
                     HFTERSFFKNRNL"
     protocluster    1..4577
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2375:4280]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2376..4280
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4577
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4577
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             362..688
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="MNFQKSYDISNISDDSNELIQGVQVFDFKNNYLFYQNFSITRCIG
                     YIDSDKLKKSDISEDVDDTFSIVSASEDDSDTNLLYKRAESSSENNYIYLFDTTNKTMK
                     ENKI"
     CDS             773..868
                     /locus_tag="ctg44_3"
                     /transl_table=11
                     /translation="MSPDNADKKSDLNPRIYFTKLSDLKISVSRE"
     CDS             1055..1696
                     /locus_tag="ctg44_4"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKIYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIRLKRLLRPSTQASVLLSYQAAAC"
     CDS             1690..2352
                     /locus_tag="ctg44_5"
                     /transl_table=11
                     /translation="VLSSGIKLKLQKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTH
                     GKAVANRALHEADLVIVCGARLGDRAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPI
                     VGDMKNVINMLLDSIGDYKVTTMWSETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMF
                     RSKAILVADVGQNQIWCANNFRIREADSSQQAVWVQWVTQFPLQSVQSLQDPTVMLL"
     CDS             2376..2675
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.5e-19, bitscore:
                     57.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLNELATIAGNQLGIKIIIMKNARLGMVRELQDKHYGGRHSATI
                     LNGDPDFLKIADAYGIDHAEAHSNKEAENIIKGIVDSEKPFILVCDVHPDTPSI"
     CDS             2688..3179
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_7"
                     /sec_met_domain="ALS_ss_C (E-value: 1.1e-30, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQEPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             3240..4280
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_8"
                     /sec_met_domain="IlvN (E-value: 4.9e-84, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.8e-61, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
ORIGIN
        1 cgacattaca gacgaagaaa aacagaactc ttgaatttat tgatatcgac cttaataaaa
       61 aacaaaatga cgactgtatt ttctgacaaa ggcggatttc catatgacac tgttacagga
      121 gcagacaatc ttgtcataat cacaaaagtg ctagacaacg gtacttcttt ggaactgtat
      181 gataccgaaa ctcaaaaatt caagcaatta aaatatttag agtttgatga taaaaacagt
      241 atcggggaaa ctataagaaa agtttcaatt gacaaaagta caaaaaacaa tctctctttt
      301 ggttttggat tgcatttcac agaacgaagc ttctttaaaa atagaaactt atgactatga
      361 tatgaatttt caaaaaagct atgatatttc taacatttca gatgattcaa acgaattaat
      421 tcagggcgta caggtttttg attttaaaaa caattatcta ttctatcaaa atttcagcat
      481 aacaagatgt ataggatata tagacagcga taagctgaaa aaatccgaca tatcagaaga
      541 tgtagatgat actttttcaa tagtatccgc atctgaagat gacagtgata caaatttatt
      601 gtataagagg gcggaatcaa gttcagaaaa taactacata tatctttttg atacgaccaa
      661 caaaacaatg aaagaaaaca aaatttaata ttgaagaaaa agggtacact ataggcggta
      721 tatcacggat aggaaaagat aatttgatga taatgatgtc ccctgataat gcatgtcccc
      781 tgataatgca gacaaaaaaa gtgaccttaa tccaagaata tactttacaa aactaagcga
      841 cttaaaaatt tcagtaagca gggagtaaaa aacaattaaa aattcatttt gcaaattatc
      901 tgtcaaaatc ctgcaaaaaa tttaatttat gggcaatact gctctttact ttttaaggta
      961 tttattgtat aattagcggt aaagtaaaaa ggtatattta atgttacaaa acaccttttg
     1021 ctcacaataa aaaggatagg agggacaaaa cataatgatc agcggtgctg aaattatggt
     1081 aaaatgtttg gaagccgagg gcgttgacat agtctttggt tatcccggtg cggctatctg
     1141 cccattttac gataaaattt acgattcgag cattacccac attcttgttc gtcaggaaca
     1201 gaacgctgct catgcggcaa gcggctatgc aagatgcagt aatcgtcccg gtgtttgcgt
     1261 ggcaacttcc ggtcccggtg caaccaacct catcacaggc attgcaaccg cctatacgga
     1321 ctctattccg attgttgcca ttacaggtca ggttcgttcc gaccttctcg gcagagatgt
     1381 ctttcaggaa gctgacatca cgggagcttg tgaaccgttt gtaaagcaca gttatctcgt
     1441 cagcaaaaca gaagaccttc cgagagtttt caaagaggct ttccatattg cctcaaccgg
     1501 cagacccggt cctgtactta tcgacattcc cgttgatatt caggaaaatg aaattgaaag
     1561 ttttgaatat cccgaaagcg taaacattat cggttacaag ccgaacacta agggacacgc
     1621 aatcaggtta aaaaggctgt tgaggccatc aacgcaagca agcgtcctgt tatcgtatca
     1681 ggcggcggcg tgctgagttc gggtatcaag cttaaacttc aaaaatttgc agaaactacg
     1741 ggtatccccg ttatttcaac tatgatgggc atcggtgtta tgcccagcga gcatgagctt
     1801 tatctcggaa tgctcggcac tcacggcaag gctgttgcca accgtgctct tcacgaagcc
     1861 gaccttgtaa tcgtatgcgg tgcaagactc ggtgacagag ctgttgcggc tcccgaccag
     1921 atgagtgaaa acacaaaggt aattcacatt gacattgacc ctgctgaaat cggtaagaat
     1981 gttaaaacag aaattccgat tgtaggcgat atgaaaaatg tcatcaatat gctgcttgac
     2041 agcatcggcg attacaaggt tacaacaatg tggagcgaaa ccgtaaagaa ctggaaaaaa
     2101 gacctttacc gtgagcctcc cgtttttgac ggctttgttg agccgagaac acttgtcggt
     2161 catctcagtg caatgttccg ctcaaaggca attcttgttg ccgatgtagg acaaaatcaa
     2221 atctggtgtg caaacaactt ccgtattcgt gaggcagatt cctcacaaca ggcggtatgg
     2281 gtacaatggg ttactcaatt cccgctgcaa tcggtgcaaa gtttgcaaga cccgaccgtg
     2341 atgttattgt aatctgcggt gacggcagtt ttcagatggg gcttaatgag cttgcgacta
     2401 ttgcaggcaa tcagctcgga attaaaatca tcattatgaa aaacgcacga ctcggaatgg
     2461 ttcgtgaact tcaggacaaa cactacggcg gcagacactc cgcaacaatt ctcaacggtg
     2521 atcccgactt cttgaagatt gccgatgctt acggcattga ccatgcagag gctcattcaa
     2581 acaaggaagc tgaaaacatc atcaagggta ttgttgattc ggaaaaaccg ttcattcttg
     2641 tttgcgatgt tcaccccgac actccgtcaa tttaatgagg tgataaaatg cagtatacat
     2701 tatcaatact tgttgaaaat caggcgggcg ttctttcaaa aatttcggga cttttctctc
     2761 gccgaggttt taacatcgac tcactcgcag taggtgttac tcaggaaccg tcggtttccc
     2821 gaatcacaat cgttgcaaac ggtgacgagt acattgttga acagcttgaa aaacagctca
     2881 acaagctcat tcccgtcatc aaggtaaaaa ggcttaacga gggcgaattt atcagccgtg
     2941 agcttgtttt aatcaaggtt cactgcgctg cctcaaaaag agccgaaatt gtcaaaacgg
     3001 ttgaaattat gcaggcgaaa atcgttgatg tatccccttc gtcagttacc gttgagtact
     3061 gcgaatgtgc aagccgcatc aacacgcttg ttgacttact caagccttat ggtatccgtg
     3121 agattgtaag aacaggtact gttgccattg acagaggcac agcttcggtt tccgtttaat
     3181 cttacagtta gcatatattt taatttatat gccgcgtttg cggtaaggag gactttaata
     3241 tgaaagacta cacaaaaaac atgacagcac caatctacta tcagtcagat tgtaaccttg
     3301 accttctcaa gggtaagaaa attgctatta tcggttacgg cagccagggt catgcacacg
     3361 ctctcaacct caaggattca ggttgcgatg taatcatcgg tctttacaaa ggcagcaaga
     3421 gctgggcaaa ggctgaggca cagggcttta aggtatatac atcggcagag gctgcaaagc
     3481 aggctgacat catcatgatt cttatcaacg atgaaaagca ggcagctctt tacaagaacg
     3541 acatcgagcc aaacctcgaa gcaggcaata tgcttatgtt cgctcacggc tttaacattc
     3601 acttcggttg catcaagcct ccaaaggatg ttgatgttac aatggtagct cctaagggac
     3661 ctggtcacac agttcgttca gagtatcagg ttggtaaggg tgtaccttgc ctcgttgctg
     3721 ttgagcagga tgctacaggt caggctaagg atctcgcact tgcatatgca ctcggtatcg
     3781 gcggtgcaag agccggcgtt cttgaaacaa cattcagaac agaaacagaa acagacctct
     3841 tcggtgaaca ggctgttctt tgcggcggtg tttgcgcact tatgcaggca ggttttgaaa
     3901 cactttgcga tgccggttac gacccaagaa acgcttactt tgagtgtatc catgagatga
     3961 agctcatcgt tgaccttatc tatcagtcag gttttgcagg catgagatat tcaatctcta
     4021 acacagctga gtacggtgac tacatcacag gtccaaagat catcacagag gatactaaga
     4081 aggctatgag aaaggttctt tctgacattc aggacggtac atttgctaag gacttcctcc
     4141 ttgacatgag cgatgccggt tcacaggttc acttcaaggc tatgagaaag ctcgctgccg
     4201 aagctcctgc cgaagtattc ggtaaggaag ttagaaagct ctacagctgg tctgacgaag
     4261 ataagctcat caacaactaa tgtcttttag ttcgtgaagt tagtttgata tattcaaact
     4321 tctgtcaccc gagcgttaca tagtacgaat ttagggtagc ttgattttca agctaccctt
     4381 tttgcgagta cctcgctcgt agttcgtgta ggtagtttgt gataatttac aactacttat
     4441 tcccgagctt aacatagtta taattttcgg ctctatgtca atagttgggg tagcattaaa
     4501 acagaataat tgaaattgac aagtggtggt tgtttaaact gccgcttgtt ttatattgtt
     4561 ttttgctgat ttgagtg
//
