LOCUS       gnlProkkaNJPHLNLP_7    13796 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NJPHLNLP_7.
ACCESSION   gnlProkkaNJPHLNLP_7
VERSION     gnlProkkaNJPHLNLP_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 20:46:17
            Original ID  :: gnl|Prokka|NJPHLNLP_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13796
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13796
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3445:3796]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3446..3796
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13796
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13796
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             290..1801
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1875..2942
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2979..3263
                     /locus_tag="ctg7_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3446..3796)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_4"
                     /sec_met_domain="PqqD_RRE (E-value: 7.8e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.8e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(3894..5282)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5530..5925)
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5932..6705)
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6711..7238)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7225..8466)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 387.1; E-value:
                     2e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_9"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8476..9570)
                     /locus_tag="ctg7_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9575..10615)
                     /locus_tag="ctg7_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQNQIPLGEASKE
                     AEQTNK"
     CDS             complement(10634..11644)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_12"
                     /sec_met_domain="PF04055 (E-value: 1e-17, bitscore: 57.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDNLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
ORIGIN
        1 gagagcgaag attatttatt cacaatagaa gaagtaccac caaatttgac gaagaaccag
       61 aaatcttttt cagggagaaa taaaagtaag ttcataatgg tgcagcattg aattattttt
      121 tggcggagtt attctaacac ttaatagttc aaaagcagat atttctttga ccaaaagata
      181 gaactaatga tgaattaaaa gttgcaatta tggttttctt cccacaacaa acgggaaaag
      241 tcagaagaat catgtacatt tgtaatccga aaactaaaag aacatcgcaa tgaaaatatt
      301 tccaagcagc agtatcaaga aattggacgc ttataccatt gagaacgaac ctattgcatc
      361 aatcgatctg atggaacgtg cagcaaccgt attaacaaaa gccatcacag acagatggaa
      421 tacggaaacg ccggtcacta tctttgccgg accggggaat aatggcggag acgctctcgc
      481 cgtagcccgc atgatggctg aaaaaggata taaaatcgag gtatttctct tcaacacgaa
      541 aggagaactt tcacccgact gccagaccaa taaagaactg gtagaaatga tggaagaagt
      601 aaaattccac gagatcagta cccaattcgt acctcccgcc ctgacgcccg accatctggt
      661 aatcgacgga ttattcggtt caggcctgaa caaaccgtta agcggcggat tcgctgccgt
      721 agtgaaatac atcaattcct cccctgctat ggtagtagcc atcgacattc cttccggact
      781 gatgggagaa gaaaacacat tcaacgtaaa agctaatatt atccgtgccg acgtaacttt
      841 cagtctgcaa ctgccgaagc tcgcctttct tttcgcagag aacacggaat ttgtcggaga
      901 atgggaagtg ctggacatcc aattaagcga agacggtatt gaagagatgg aaacgaacta
      961 cgaaatgttg gaaatagagc aaatccgttc actcatcaag ccacgcaaac agtttgccca
     1021 caaggggaac ttcggccatg cactattgat tgccggttca aaaggaatgg caggagcctc
     1081 tgttcttgct gcccgcgcct gcctccgttc gggagtagga ttactgactg ttcatgcacc
     1141 aatgtgcaac aacgacatct tgcaaacctc catacccgaa gcaatcgtag aaaccgacat
     1201 caacgaaacc tgttttgccg tacctaccga cacggacgac tatcaagcag tcggcatcgg
     1261 tccgggactg ggacgaaacg aggaaacgga agctgccttg ttggaacaac tggaacactg
     1321 ccagactcct gttgtggtgg atgccgacgc acttaatatc ctcgccaacc accgtcatgc
     1381 acttacccac ctgccgaagg gttccatcct caccccgcat ccgaaagaac tggaacgtct
     1441 gaccggcaaa tgccaggact cttacgaacg tctgatgaag gcttgcgaac tggcccgtgc
     1501 cgcccatgtt cacattattt taaaaggagc ctactccgcc atcatcaccc ccgaaggtaa
     1561 atgtttcttc aacccaaccg gaaatccggg aatggcaacc ggaggtagcg gtgacgtact
     1621 gaccggagta atcctggcac tacttgccca aggttatccc accgaagaag ccgctaaaat
     1681 cggcacttac attcacggac tggcgggcga tgtcgctcaa aagaagcaag gaatgatcgg
     1741 aatgatcgca agcgatatta tcacctgtct gccgacagca tggcgacttg taagcgaata
     1801 aaagttaaga acttacagtt ttttcaataa cttcattaac tttgttttca aaaccagtta
     1861 aaaaagaacc gaatatgaaa aagttgatta tagcagcagg actactaatg acaacgtccg
     1921 cctatgcaca aaccgaagta ctgacagggg ttacccgagg aaaagactat ggagtggttt
     1981 acagtcttcc caaaacccaa atagaacttg aaataaaagc caacaaagtc aactatactc
     2041 cgggagaatt cagcaaatat gctgatcgtt acctgcgact gaccaacgtc tccgccgacc
     2101 ctgaagagta ctgggaactg gctagcgtaa aagtgaaatc cgtaggtgtg cccaacagcg
     2161 aaactacgta tttcgtaaaa ttgaaggata agacagtagc accgcttatg gaactgacag
     2221 aggatggcat tgtgaaaacg atcaatgttc cttacagcaa tagcagtgta ggcaaaaaag
     2281 ctgctcccgc ccccgcagtc ctccaaaaga aagcgaatcc tcgcgaattc ctgaccgaag
     2341 agattctgat ggctagctcc accgccaaga tggccgaact ggtggctaaa gaaatctata
     2401 acatccgcga aagcaaaaat gccttattgc gcggacaggc tgacaatatg ccttcagacg
     2461 gagcacagct taagattatg ctcgacaatc tgaatgcaca ggaagaagcc atgacgcaaa
     2521 tgttctccgg cacctgcaac aaggaagaga gaacattcac tgtccgcctt acccctgaca
     2581 aggaatttaa caatgaagtt gctttccgct tctcgaagaa gttaggtgta gttgccaaca
     2641 atgatttggc aggaactccg ttttatatca gtctgaaaga cctgaaatcg gtcaagatac
     2701 cacaggaaga tggtaagaag aagaaagatt tggatggaat cgcctacaac gtacccggac
     2761 aagctatggt tacattgacc gacggcaaaa agaaacttta cgaaggtgaa cttcctatta
     2821 ctcaatttgg tgtgatagaa tatctggctc cggttttgtt caacaagaat tctaccatca
     2881 aagtttattt tgatccgaat acgggaggat tgctcaaagt ggacagagaa gaagggaaat
     2941 agaaaaacga gaaagtgaac ttctaaaaaa caaagaatat ggttggtgaa ggacatgcat
     3001 tcgacatgat acgccgaata aaagagggac gggaagcttc ccgcctacgt cgtgaacgtg
     3061 ctaacgacaa gttgaagcat ttaaaccgtg caaacgaacc ttatccacta cccaatacca
     3121 ctcccgaaga aatggaacgt atcatccacg actcggagaa aaagaaagag aaagacagca
     3181 attattttgt ttggggaacg cttattatca tgggagtcct gatagcaatt gccgtcatac
     3241 tttgggctgt atttatcaaa taaataataa taaattcacc acagaggaca cggaggacac
     3301 agaggtttaa tcttttttat tcactataga gtaacacaga gtctcacgta ttgagaatcg
     3361 tatttatcgc tctgttttac ttgcggaaag agagagaaga actctgtgtc ctccgtgtcc
     3421 tctgtggtga aatataaatt cctatttatg cgactggtat caccagtttt ataaatccat
     3481 ctttctgcat ttgagaaaga taagccgata cacgcgactc gtagccctct tcattttgaa
     3541 aatggtctgc gagtttttct ataatctcac gaacattgcg ttttccatct atcagttccc
     3601 atacagccgt accgtgttct tccaatttca catgaagttc tttcgacatt cctttcggca
     3661 caaggaagcg ttgcatccac ggatatttaa aacggggaaa ggagagcaca attgtctccc
     3721 cttccctttc tgctgtaata tgttcactgc gacagggaat gacctctaac aggttgattt
     3781 tctctttggc agccatactt cttatttttt atttcagagt attcatactg ataccctttt
     3841 gtttacacct tgatacaaaa ttcctttgtt actttaggta ttgaatttcc cagttacttt
     3901 tggatattcg cctcttccag accgtatccc ttcttcttgt tctctgcctt caacatcaaa
     3961 gccacaatca gagcaagtac accaaagaga gcaaaaatag tcatcggcaa cgtgtagtca
     4021 taagtctgtg caccgtctac taccggacct ttgcaataag tattcaacac ccatccgatc
     4081 aacaaaggaa cacccatcaa tccccagttc tgtacccaga aaatcaatgc gtatgcggta
     4141 cccaactgtt tttccggaat aatcttcgga acagacggcc acatagctga aggcaccaac
     4201 gagaaggcaa atcccaatat aatcatgatg atagtagcaa accaccatat attcagtata
     4261 ggcagagcaa acatcgtatg cacaaaaata agcatcactg atccgattat catcaatgtg
     4321 gctcccttac cgatacggtc ataaagcgaa ccgaacaacg gagtcaggat aatcgcacca
     4381 atcggcaaca atccgggaat cgttcccgcc aacttcggat ctacgttata tttctgcacc
     4441 atcaagtcgg cagcatactt gataaagggg aatacagccg agtagaacaa tacacatagt
     4501 aatgcaatca accagaatcc tttattggta ataatataca caatatcttt catacggaac
     4561 ggttcttccg gttccaatcc ctctgcatcc aaagaagcat ccaacttctt atcatagaaa
     4621 gtataaagga aaaaagcaat cgtacccacg cacaacataa tcagacaaaa caaaatcgga
     4681 gcaggaatat ttgtatggaa tgtgccactc tcatccgtag atccgaaaaa gtctgccaaa
     4741 ggaactgtca ataccatcgc cagagttgtt ccgatacgtg ccgtagccat ttcaagtccc
     4801 atagccaatg ccatttcctt gcccttgaac catttcacta taatcttgga aacagtgata
     4861 ccagcaatct ccacacctac accaaagata gcatatccca atgcagccaa cgtcacctgt
     4921 gttttgaatc cgaagagcat ggcaccttcc ggaaaagtag tagaaatcgc atagtatttc
     4981 aatccacaac caaacaccat caataagcaa gcccccattc cggtgaaacg aactcccatc
     5041 ttatccaaaa tgataccacc gaagatcagc atcaatagga atacattaaa ccacccgtaa
     5101 gcacttgtga agaaaccata atcaagactg tcccatagta gttctttctc aagcatgggt
     5161 tttagaggag acattacgtc ggtgaggaaa tagccgcata gcatagtaaa tgcgaccaat
     5221 gctagaacac tccatcggag tacggcggag tcattcaatt tctgtttcaa atgttctgtc
     5281 attgttatat ttaaaaaagt agttaataat cttatacagc caacaaaggt agttaaatct
     5341 cgtttgtttc tatcacaaag agattgtttt tacaagaaaa agttaagtgc ggattacact
     5401 gaccacgcgg aacattgaaa atccgtgtaa tctgcgtaat ccgcacttaa atatcaaaga
     5461 aatgcagcat ccgtctgcac cttcccatta atggttttac cccaaagtct tacttgacga
     5521 cggagtgaat tactctgctg caggagcagg agtttcagta gccggtgccg gagtttctgt
     5581 agcaggtgca ttggtagcag gagcttcagt ttgcggcgca gccgtacctg cgggtaagtt
     5641 atacgggtta gtctgttgtt ctttctgtgc ctgttccaac actgcgtctt tagcaacagc
     5701 agagcgagga actacataag cagtagcaat gctcattaca accataaaga tggccaggcc
     5761 ccatgttgct ttttccagaa agtctgtagt cttgcgcacg cccatgatgg cgttagatga
     5821 agagaaacca gaagcaagtc cgcctccttt tgagttctga atcagcacga tgaaacacat
     5881 caacaaggct gcaataacca ttaagataac gaataataag tacattttta gttattttga
     5941 attagcgtta ataatcaatt tctccaaaaa tctgatttgg tctgcaaagt aagcattttt
     6001 ttttggatat ttcaagctta attttttaat tatttcaaga gcttttgaat atcgttgctg
     6061 tttaacatag atttttgcca aagtttccgt aaaacagctg tcatcttcct cttcttcctt
     6121 tatcgtttct tcttcggtaa gttcgtccga agaggttggc gaagatggca tttcttctct
     6181 taaaggtttc atgcagaggg gagagtcgct ctcgctcttt tctataaaat cgtcaatcag
     6241 ttcgaagcct ttgagtttgg gcgtttcttc agccggctgt tccgtggccg gagtctcctc
     6301 caaaaggaaa gaggtgtaat ccatcgaata gtcgaaactg gtccgggcag tcacctcttc
     6361 gggtactgtg gacaagaaag cgtcgatcaa tgctaatgtg cggtctacgg acggttcgtc
     6421 tttcagcacc tccgtgagag gtactccctt tttccgcgcc tgcacatcat agcggtcacc
     6481 ttcaatcaac cggaacaact gccgtctgtc tgcaatgtaa agaactgctt tccgcagttc
     6541 tccaccgaaa ctaatatcat ggagaatata cagattcttc agatacaaca gacgaagtga
     6601 ctgaaaatac ggatacctcg caagaagatt gcgcagttcg tacaaagtat ccctattcag
     6661 cgtctcggga tgctgaatcc attgttgaaa gttaacagaa gtcatttata ttaccagttt
     6721 gctacagttg cattaaaaat ttggtcggtg atctctttag acatttcagc aatcaatccg
     6781 tcctgtacgg cagtcaacaa ctgggtagag tcgtaggtac ggaacgcaga aaactgttgt
     6841 tcaaagtctt cggcatgatt ggtgttgttg acaaaacgca cattgacggt gatagtcaac
     6901 ttcgtctccg aagaataacc gtcggcagat actgcctggt tgtactgatt gtaccctgtg
     6961 atttctccgt caatctgcaa gtcggcattt tgactcggct tgagcagttg cagacgggtc
     7021 tgccggatga agatatcttt caggtcctca ttgaatttgg ttgccaacgg agcatataca
     7081 tactccgact tgatcgggaa gtcggctatc gaaatggtct ttaccttatc ataattgata
     7141 gacgatccgt taaacttata ggaaacagtg cacgcaatga ctaccaacgg caagccgaac
     7201 agtagcaaag ggcgtattat tttcttaatc caattcatat tcttttattt ttctataaag
     7261 tgtacgctcg gaaatattca agtccttggc cgcactcttc cgctttccat gatgcctctc
     7321 aagtgccttg cgtatcattt ctttctccac ttcgtccagt gacaaaggag attcttctac
     7381 atattcttcc gtgtcttgta tgtcatcgtc atccttgcaa accgtaggct gcatggtgtg
     7441 aatgatagca ggtaccgaag gttgatgtgc cgtcactacc ggagtagtaa ccaccgttcc
     7501 catttgccct acctgcccca cctgtccggc acgttccgcc atcaggttgt gcaccatctt
     7561 cttcagctcc gccacttcct ggcgcatatc gaacagaaca gaataaagaa tctcccgttc
     7621 gctctcaaag cctttactct cacgcgttcc catcagcgcg ggaagacgtt gcgtattttg
     7681 tgcaggaaga taattctgca agatagcagc agagatctcc ctgttggttt caatgataga
     7741 tatttgctcg gtgatgttct tcaactgacg aacgttgccg ggccacgggt aagccaataa
     7801 ctctttcttc gcatcctccg tcaactggat agcaggcatc cggtatttct ctgcaaagtc
     7861 tgcggaaaac ttacggaaca acaaaagtac atcgtcacca cgttcacgca aaggcggtat
     7921 ttggataggc accgtattca accggtaata taaatcttca cggaaacgtc cttctgcaat
     7981 cgcttgtgtc agattgacat tggtagctgc cacaatacga acatccgtct tttgcacttt
     8041 ggacgaacct acttttataa actcgccact ctccaacaca cggagcaaac gcgcctgggt
     8101 aggcatcggc aactccccta cttcatcaag gaaaatagta ccaccgtcgg cttcgccaaa
     8161 ataccctttc cgttcgccaa tcgcaccggt aaacgcaccc ttctcatgcc cgaacagttc
     8221 ggaatcaatc gtgccctccg gaatagcacc acagttgaca gcaatatact gtccatgctt
     8281 cctccggcta tattgatgaa taatctgcgg aaaactttct tttccgactc cactttctcc
     8341 ggtaatcagc acagacaaat cggtaggagc tacctgaatg gcaacatcta tggcgcgcga
     8401 caatgcttcg gtattaccta taataccgaa acgttgtttc acttgttgta tctctgctct
     8461 cgtcatcact cgtttttaat cttcgtctac tgtatccagc ttcagtttat cactatcgtc
     8521 acgtttctcg taatactgtt tacgcaacgg attggcacga gccacttttt cccgctgacg
     8581 attacggaac acatcgatgg caacatagat tgcctgacgg aaagaatctt cacaagccaa
     8641 tcccttgcct gcaatatcgt atgccgttcc atgagccgga gaagtacgta ctaccggcag
     8701 gcctgccgta tagttcaccc cgtcttccat agccaaggcc ttgaacggag ccagcccctg
     8761 atcgtgatac atcgccagga taccgtcaaa atgagtataa ttgcctgaac ccataaagcc
     8821 gtcggccgca taagggccgt agcaaaggat tcctttctct tccatttctt tcatggcagg
     8881 gataatcact tcctgctctt ccattcccaa caaaccaccg tctccggcat gaggattgag
     8941 agagagcacc gcaatacgcg gagcgccgat accgaaatcc tgtttcaggc aacgatggaa
     9001 tatcatcagt ttctcctgaa tcagttcttt ggtaatcgta gtcgcgatct ctctgacagg
     9061 gatatgtgtc gtcaccaaag ccacccggaa gtcattcttc atcaaaatca tcaatgactt
     9121 atcaccattg cccagacgtt cttcgatata ttccgtatgt ccggggaagg agaactcttc
     9181 cgactgaatc gtatgtttgt tgatcggagc tgttacgata acgtctatca gcccttcgcg
     9241 atattcttcg atggcacgtt ccaaagcccc cagcgcagct ttaccggctt cggggtcggg
     9301 tttggaaaat tccactttca cctcatcatc cgtacagttc accacgctca aacggttgta
     9361 ccccgcttcg gtagcagagt tgacaatgct gaaattggtc tgtatatcca gcgctttgcg
     9421 atgataagcc gctactttcg gtgagccata aatgatcgga gtacatagtt ccaacatcgt
     9481 agggtcggaa aatgtcttaa gaatcacctc atagcccacc ccgttaatat ctccttgggt
     9541 gatacctatc cttatcttgt tatcttccat gtttttattt attagtttgt tccgcttcct
     9601 tagatgcttc tcccaatgga atctgattct gctgaacttc attcggaagt ttcagtgtat
     9661 acagagatgc ttccatctgg cgtaccaggt tgcgtttcat tttatcaggt gaataaacaa
     9721 atatttctgc tgttataatt cgttggtttt tctcgtccag acgagtatga gatacatacg
     9781 ggccacccat aaagtcgccc ttcatacgcc acaggccacg tgcttccatt gtgtagctgt
     9841 tttgtacatt gatcggacgg acatcggtca gcaaactatc ggtcgacata taaacgcctt
     9901 ccttgaatcc ggggatattg gctttcatca cggagtcacg tttgtgcaca aaatattctt
     9961 tggtaaacgt atccttgtca gtgtacggat aagagtacat cacaaagtta cggtcagcac
    10021 tacctgtgtt ggtagaagcc cagaagaaat catccccggt ctttgaatta gccagttcgg
    10081 catccaccca gatgtcgcat ccgaacaaac tgtccacttt ctgcgaaatg aaattactgt
    10141 gtttcccttc tagaaacgta atctgacggt tcatttccgc acgggtaaag aagtcgacaa
    10201 tcgtcttttt gttctcttcc acaaacttct cgaactcttc ttcgttcgga gcctggatag
    10261 tcaatatcat ctgcggattg gcatacacgt ccttcgcata tttgaacgag gctttcgtat
    10321 atatatcctg tatatctaca ataataatgt tacgtatcaa cttcagcgta gaatcataat
    10381 ctttcggtga agtatacata atccggaaag aaggttccga ctgcggcaaa ccgggcatat
    10441 cagcatcgag cgcatcatgc aacgcccttc cggcagcacg atcccaaaca ccgtgatcta
    10501 ctacaaccaa aagctcgtaa gcacgaccac tagaggtgtg atttcctttc agaccacaag
    10561 atgcaacgac aaaggctacc aaagcgatgc ataaaataaa agagtacttt ttcatgatgt
    10621 tcggttttat atattaactt tcattatttt tctcctgttt cgctgtcgac agcataccgc
    10681 aagcggcaaa aatatcttcg cctctggatg aacggatagt ggtgaaaagt ccgtgtgacg
    10741 tcagattatc acgaaaacgg gtcatcgtat ccatatccgc cccctcgagg tctacccccg
    10801 gtatggcatg aaaacgaatc agattcaccc tgcaatccag cccgcgaaga agtttcagca
    10861 actctttggc atagacctgc gaatcattga gccctttaaa aacaatatat tcaaacgaaa
    10921 gtcgacgttg tttactaaaa tcatagtttt ttaacagttc caccatttcg gtgattgaaa
    10981 acgccttttc cgccggcatt aattcagcac gctgaacggt cagcggagag tgaaggctga
    11041 tggcaaggtg gcagtcattt tcttcgataa aacgctgcaa tcctttccgt agcccgacag
    11101 tagaaagcgt gatacgcttc ggactccatg cgtaaccgta ggtagcggtc agtagttcca
    11161 atgctttcaa tacctcatcc aggttatcga gcggctcgcc cattcccatc attacgacat
    11221 tagtcagttt gtcccgttcc ggcagcgaat gaatctgatt catgatctgg ctggcggtca
    11281 ggttagccgt atacccctgt ttgccggtca tacagaactt acagttcatc ttgcaaccta
    11341 cttgtgacga cacgcacaac gttgcccggt catcatccgg tatataaacc gactctacaa
    11401 aatggttctc acccacttta taaagatact tcaccgtacc atctacagag cgcatttcat
    11461 ctaccggagc ttctgctccc acctcatagt tctgcttgag caactcccgg tgtttcaatg
    11521 acaaattagt catatcatca atcgaggcta ccttcttttc gtaaagccag gatgcaatct
    11581 gcttggcagc aaagccgggc atacccagtc tttttgtcaa tgattgaagc tctacaagag
    11641 tcattcctaa aaggggatat ttagacattc ttctttctgt tgatagttta tatctgcaaa
    11701 tgtaaggaaa taaagtcgat ttccgtatag caggaatgta aaagttaaca aaaaagggaa
    11761 gtatgcctcc gttatgattc aaccacgctg atatattgaa gtagcttttg cgccatttca
    11821 gaatcctcgc cattcttttt cacttcatga ccgtacgcct cacggaaaca agccagcgcc
    11881 tcttcccgtt cattacaaaa gctgtgcaaa acccctaagt tctgacaagc cagaatcgta
    11941 tcttcttcct cccatcccaa atacttcttt cgcagttcga actctctgaa gaaagcctct
    12001 ttcgccattg gataattctc caacttcaca taagcctgtg ctttgtaata atataccaga
    12061 caggaagcat tagggtcagc atcatcgtga atatccaaag acgtcgcaat acgaatcacg
    12121 ttatcatagt ctttattcat gtaatactgc tgcataatat cacatctcaa tgcctcatat
    12181 cggacagtca gttccgccag acgcggtttt tcgctgaaat acatttcatg cagaagagac
    12241 tcacggaaga ataaagtaga cgcctgctca tcgccacgtt cattcatcac tcgtttgaat
    12301 tccctgcaca gataatacaa ctgtttatga caagcgacga tctgtttttt attatctatc
    12361 tgtatagcaa tgtccaacgc ctgattcatc agcatccatg cttcatcgta tcgtttgata
    12421 taataaagac atttaccctg catacgcaaa catttagcca ctccaccgga cagtctgcca
    12481 ttcaatgact cgtgcatttc agctactttc cggaatttct cggcagcact ctcttcctca
    12541 tccttatagt aatcacaata agccagatat tcggaaagtt caatgacttc tgcctgactc
    12601 ttctcgtcag caaaagccgc atgataatca agcgccctat tcaaatagat cgccgcttca
    12661 ttgtattgct cattgtagta atatgccaaa gctagatttc gacaggtgtt ggcaatctcc
    12721 agttccggag tcggtactat gttttcctgc atcaccaatg ctttcaggaa acagtcgcat
    12781 gccgtttcgt attcttcatt acgggcatac cggcatccct cattcatctt caataccgac
    12841 ttggctatta gtggcatggc agcaccttcc atactcttct cactcacagc agctgccgcc
    12901 ttcgtcagat ggaaagaact gctcaagaaa gtagccatat cattagcaat gacaggaatt
    12961 aaaaaagaat cgatctcatc aaagtccaat tcggcataga cttcaggcgt aacttcagga
    13021 ttgtcgttca tgatcgcctt ccagctatct tccaacagag aacgattcgt gcgatacaga
    13081 atctcgaaaa tctccacatc acaaatccaa tccttcaata tatcccattc ttgcatctta
    13141 tagcattgat aggtaatctc cactttatag cgatacgaat catggtagca gaactgtttc
    13201 atgcgatagt tataatcggc aaaagtcaac ggatgggaaa ggatctcttc ctcatccagc
    13261 agagcggaaa taatttcatg gcgactatca tctatacatt cgtcatcttg agcgaaatag
    13321 cgttcgatcg cctctaccat ttgtgtgtca ccaatgcaat atcgtcctcc tttgttggtg
    13381 agccagctgc tcatttccac tctcaactgc gaccaaagta tctgattaat gtctgccatg
    13441 ctcttcactt catcttcggt aaatccttct aaagtaagtg aaagcatcag aagcgttctt
    13501 ccaatctctt cggaaccata atcagccgac aaacgccgta gcacactgtc atagaattgc
    13561 ccaacctcat tgagccggca atatccacgc atatattcat tgagagcatc gtactgaccg
    13621 aacgaaacca gctcgttgag caatacactc aaacagcgcg gttgtttagc cagcacccac
    13681 gaagcaagaa tatcttcctg ctgtgcagac aaagccttgg agtaagtaga caaatattgc
    13741 tttgagaacg acttggcatc cgcctgtgaa aagccattca actggaaatg agcata
//
