GCA_003459865.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaDDDKOKPE_2 (original name was: gnl|Prokka|DDDKOKPE_2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS-like	23,165	65,111

gnlProkkaDDDKOKPE_23 (original name was: gnl|Prokka|DDDKOKPE_23)

Region	Type	From	To	Most similar known cluster		Similarity
Region 23.1	lanthipeptide-class-iv	235,349	257,205

Region	Type	From	To	Most similar known cluster	Similarity
Region 2.1	NRPS-like	23,165	65,111
Region 23.1	lanthipeptide-class-iv	235,349	257,205

Compact view

gnlProkkaDDDKOKPE_2 - Region 1 - NRPS-like

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Location: 23,165 - 65,111 nt. (total: 41,947 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 23164 - 65111:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg2_44

AMP-binding (14..381): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DFFTIGIIYK
Nearest Stachelhaus code(s):: Ile DFWNIGIIYK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaDDDKOKPE_23 - Region 1 - lanthipeptide-class-iv