LOCUS       gnlProkkaHHJEEDLC_115  11972 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HHJEEDLC_115.
ACCESSION   gnlProkkaHHJEEDLC_115
VERSION     gnlProkkaHHJEEDLC_115
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 21:16:42
            Original ID  :: gnl|Prokka|HHJEEDLC_115
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 29016
            Orig. end    :: 40988
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11972
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:8572]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8572
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11972
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11972
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             238..606
                     /locus_tag="ctg103_25"
                     /transl_table=11
                     /translation="MDAIILQENIEGLLSLVRMLLPGGGSAGCVYLDDLSALQRSIHEK
                     INDLYSQRGETPEQDATLCLAILQGYNVSMYANPEDEERKQAVLTRSLSLLDVLPPSLL
                     KQQLSAVCHGMQELCEIN"
     CDS             624..2579
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_26"
                     /sec_met_domain="Poly_export (E-value: 2.5e-18, bitscore:
                     57.3, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCLMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLED
                     HPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEA"
     CDS             2576..3034
                     /locus_tag="ctg103_27"
                     /transl_table=11
                     /translation="MIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIPKN
                     TNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKGSG
                     KKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             3049..4197
                     /locus_tag="ctg103_28"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             4363..4980
                     /locus_tag="ctg103_29"
                     /transl_table=11
                     /translation="MIVRSIDTLLSCGIERIVIGTGYKQEVYEELKTDYPMLETCFSPR
                     YAETNSMYTLYNTREILGNDDFLLLESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQ
                     YYVEHDDNFRLSSCSVNKNKLNAKGELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEY
                     ELLRISCSQSPVYVHKVEGLKWYEIDDISDLEYAEKYIVPYC"
     CDS             5001..5858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 81.7;
                     E-value: 7.7e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_30"
                     /sec_met_domain="CTP_transf_like (E-value: 3.3e-13,
                     bitscore: 41.4, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 6e-55, bitscore:
                     177.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-25, bitscore:
                     81.7, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEVL"
     CDS             5812..6300
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 114.6;
                     E-value: 7.4e-35)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_31"
                     /sec_met_domain="phosphonates (E-value: 2.9e-62, bitscore:
                     201.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.7e-35, bitscore:
                     112.9, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRMLFKLKIQSRFCNKIKAGKASQITDDFMIIARIESLIAGKPV
                     SDALERAFAYVQAGADGIMIHSKNKSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYES
                     ELCDWGVNIIIYANHMLRAAYPAMMNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             6317..7441
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_32"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.3e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             7451..8572
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.8e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg103_33_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_33"
                     /sec_met_domain="Aminotran_5 (E-value: 4.5e-31, bitscore:
                     99.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     VCALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        7541..8548
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg103_33_Aminotran_5.1"
                     /evalue="2.80E-34"
                     /label="ctg103_33_Aminotran_5.1"
                     /locus_tag="ctg103_33"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRVCALGEIEVDDIENFFKVLKAALNHY"
     CDS             8569..8679
                     /locus_tag="ctg103_34"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFR"
     CDS             8802..9041
                     /locus_tag="ctg103_35"
                     /transl_table=11
                     /translation="MTTADPNGPYNALAVLYPYKKAPVVIGDNVWIGANVTILPGVTIG
                     DYVVVAAGAVVTKDVPSGVLVAGVPAIVKKRFNK"
     CDS             9038..10483
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_36"
                     /sec_met_domain="Polysacc_synt (E-value: 2.5e-32, bitscore:
                     103.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKTSLKNKAICGIFWSAVERFLSQGIQFVVTVIMARFLLPSDY
                     GMVGMLAIVLQLSQTLMDSGFTNALIRYKERTEIDYSTVFFFNILASLVIYFLIFFLAP
                     YISWFYKIGQLVEITRILSIVIVLNSFAIIPKTKLIIAVDFKTQSKVSFIAALVSGIIG
                     IWAAYLDFGVWALVGQTLVNGLLIVVLYAYFCRWKPLWIFSLKSFRLLFAFGSKLVLAN
                     ILNTLYKNLYAIVIGKKFSSVDLGFYTRAEQFAQFPSYNLSAIISRVTYPILSLVQNDN
                     DRLSALYRKYVRLSSAFIFPLMILLIVIAQPLVLLLLTEKWIGVVVLLQILCLDWMFDH
                     LSSINLNLLYVKGRSDLALRLEVIKKVLATGILLLSIPWGIVGMCWGRVMYSLIAVYLN
                     TYYTESLIKLSLIRQMRDILPSFFLALIMGGGTWYMILLLEGEIVQIVVGSVIALLLYG
                     TLLYCFSRSLFDEIWAVILKIKR"
     CDS             10483..11205
                     /locus_tag="ctg103_37"
                     /transl_table=11
                     /translation="MDKLSLIISKIRRNHWYRTYMRPIYLFVYGNRKLKNRNRIFLQYS
                     QELLTNFHQAMNEVGIPYWLEFGTLLGAVREHSFISHDFDLDVGLFKEDYSDIIREVLK
                     KYGFKRIRCITALDFIDAYEETYLYKGVTIDLFLFSREKNCDGVYCYDFVPVYSDIKRT
                     KKGDNAIRRIHFPRIDLIEYSFIGINTFVPENYEEHLCMHYGKDYMIPNPHWKDSDAQH
                     TDIFYGREIRIELFDKSK"
     CDS             11219..11857
                     /locus_tag="ctg103_38"
                     /transl_table=11
                     /translation="MFYLFFLLIVLFLLYIQSRKRQYSTVAGICVVLFLLYIQSRKRQY
                     STVAGICVPIIIIFVVICRYRVGYDYLTYYTLIENEEEAQILYLFSPLSIVWAEIALYF
                     ESPQMLFVLFGLPTFALLIFTLKKYSKDYALSVTILICFFFFTSLSIIRQALALAICFY
                     GYRFIVKRSLIKYILCILIAALFHPSAGVAIIIYWLPFLKFRLVVTYYL"
     CDS             11889..11972
                     /locus_tag="ctg103_39"
                     /transl_table=11
                     /translation="MLNILGVYTSYLDGKMDIEGGKYTQLIY"
ORIGIN
        1 gtttccgttt catgcttgat tattcggaag aatcgataag catgaacagt tctcctttgg
       61 ctcgtggcga aaaggttcgc gtgatcaaag gtccgttgac gggtcttgtt ggcgaactgg
      121 tcaatgtgga tggtaaaagt aagattgctg ttcgcttgaa tatgctggga tgcgcctgtg
      181 ttgatatgcc tgtcggttat gtagagccga ttatggcggc tgtttaaggc aagggatatg
      241 gatgctatta ttttacaaga aaatatagag ggtttattaa gtttggtacg tatgctgctt
      301 cctggtgggg ggagtgcagg ctgcgtgtat ttggatgatc tttcagcatt acaacgatcc
      361 atccacgaaa agattaacga tttatattct caacgggggg agacaccgga gcaggatgct
      421 accctgtgtt tggccatcct tcagggatat aatgtgtcga tgtacgccaa tccggaagac
      481 gaagaaagaa aacaggctgt tttgacccgt tctctgtctc ttctcgatgt tcttccccct
      541 tctcttctta agcaacagtt atctgccgtc tgtcatggga tgcaggaact gtgtgaaatc
      601 aactgaaact tttttatttg tcaatgaaaa tacaacgact ttttagcatt ctactatttt
      661 gtttgatgct gggaagtggc tcgcttatgg ctcagtccat gagtgactca caggtactgg
      721 aatatgtaaa agacggcatc cgccaaggca aggaacagaa gcagcttgct tccgaactag
      781 cccgtaaggg tgtaaccaaa gaacaggcaa tgcgtgtgaa gcagctatac gagcagcaga
      841 acaatgtaaa tacctcgaaa tcaacgggca cggacatcaa cgaatcccgc ctgcgtgaag
      901 agactaagaa gaatacttcc gatatgctgg aggatcatcc gactactcag gaccttgccc
      961 gtggtgatca ggtcttcgga cgtaacatct tcaatacccg caacctgacg ttcgagccta
     1021 gtgtcaacct tgccactcct gccaattacc gtcttggtcc cggtgatgaa gtcatcattg
     1081 atatctgggg tgcgagccag aacacgatcc gccagcaaat ctctcctgaa ggtactatca
     1141 acattcagaa gatcggccct gtcaacctta gcggtatgac agtctctgcc gccaatgact
     1201 atctgaagaa cgccctgaat aaaatatata acggtctgaa taatactacc gatcctactt
     1261 ccgacatccg tctgacgtta ggtaatatcc gtactattca gattaatgtg atgggagaag
     1321 tcgtacagcc cggtacctac gccctttctt ccttctctac cgtcttccat gcgctttatc
     1381 gtgcaggcgg tgtgagtgat atcggtagcc tccgaaacgt tcagttggta cgcaacggaa
     1441 agaatattgc caccatcgac gtctacgaat tcattatgaa aggcaacaca caggatgaca
     1501 tccgcctaca ggaaggtgac gttgtgattg ttcctgccta tgatgtattg gtaaagatta
     1561 gcggcaaggt aaaacgtcct atgcgttttg aaatgaagaa agacgagaac cttgctactc
     1621 tcattaaata tgccggcggc tttgaagctg atgcctacac ccgttcatta cgtgttgtcc
     1681 gtcagaatgg tgaggaatac gaagtcaaca cagtcaaaga tatagattac aacatttata
     1741 aaatgcgtaa cggtgacgta gtaaccgccg aagccatcct taaccgcttc acaaacaaac
     1801 tggaaatccg tggcgctgtc tatcgtcccg gtatctacca gctcagcggt aaactgaaca
     1861 cgatccgcga acttgtccat gaagctcagg gtctgaccgg tgacgctttc ctgaatcgtg
     1921 ccgtcctcta tcgccagcgt gaagacctga ccagtgaagt tgttcagata gacattaagt
     1981 ctatcatgga cggcacttcc ccaaaccttg ccctaatgaa gaatgacatc ctctacattc
     2041 caagtatcca tgacctggaa gaccggggta atgtcacagt tcacggtgag gttgcccacc
     2101 ctgattccta tccttatgcg gataacatga cacttgagga tctgatcatt caggccggtg
     2161 gcttgaaaga agccgcctct actgtccgta ttgatatatc gagacgaatc aagaatcctc
     2221 gtagtactgc ggataatgat acgattggtc agatgtatac cttctcttta aaggatggtt
     2281 ttgtaataga tggtcagccc ggttttatcc ttgagcctta tgatcaggtt tatgtccgtc
     2341 gcagtccggg ctatcaggca caacagaatg tagccattga aggtgaaatc cttttcgggg
     2401 gaaattacgc catgaccagc cgtgaggaac gtctttccga tttagtgaat aaagccggcg
     2461 gtccgaccaa ttatgcctat ctgcgtggtg cgaaactgac ccgtgtggct aacgctagtg
     2521 aaaagaaacg tatgggtgat gtaattcgcc ttatgagcag gcaattgggc gaagcatgat
     2581 tgactctttg ggtattcgtg ttgaagatac ttttacggtt ggaatagatt tggaaaaagc
     2641 cttgagcaat cctaaaagta atgccgatct tgtcttacgt gaaggtgatg tgatctccat
     2701 acctaagaat actaatactg taactatcaa tggtgctgtc atggttccga atacggtttc
     2761 ttatatgaag ggaaagaatg tggattatta cctgaatcag gccggtggct gttctgataa
     2821 tgcaaggaag agtaagaagt tcattgttta catgaatggt caggtgacga aggttaaggg
     2881 tagtggtaag aaacagattg agccggggtg tgagattatt gtgcctggta aggctaagaa
     2941 gaaagggaac atagctaata ttttaggtta tgctacttcc ttcagttctt tgggtatgat
     3001 gattgcttct attgctaatc ttataaagaa ataatagaat ttacttttat gtcagaacaa
     3061 cgacaggata aaaacttgct ctctgaacca cacaagacag aaagtgatga gatagaaatt
     3121 gatttggtcg atatctttcg caagattatt gctattcgta aaaaattata caaagccgtt
     3181 ggaattggtt ttattattgg aataattgta gcggtaagta tccctaaaca gtatacagta
     3241 aaggttaccc tttctcctga aatgggtaat gcgaagggga gtaatggttt agccggactt
     3301 gctgcctcgt ttttaggaga tggggctcta ataggggaaa gcacagatgc cttgaacgct
     3361 tctctttcag cagatattgt ttcttcaact ccttttttat tggaactttt agaaatggaa
     3421 gtctccgttt ctaaaaagga tgataaaatg actttggggt cttatctcga tgaagagtca
     3481 tctccttggt gggattatct tataggtttt ccgggcatag taataggagg agttaaatca
     3541 ttattcggag aagatacggt tcctgccagt ggagggcggc aaggaactat cgaattgacg
     3601 aaagaagtaa atgagaagat taattttctt aaaaagaaga ttagtgcatc cattgataag
     3661 aaaaccgcca taacgagcat tacggtcacc ttacaaaatc cgcagatcac tgcggttata
     3721 gcagattctg tcgttcataa attacaggaa tatattattg ggtatcgaac ttcaaaagta
     3781 aaagaagact gtgcgtattt ggaacggttg tttaaagaac gtcagcagga atattatgct
     3841 gctcaaagaa aatatgcgga ttatgtagac gcccatgata atgtggttct tcaaagtgta
     3901 cgtgctgagc aggagcgttt acagaacgac atgagtttgg cttatcagat atatagtcag
     3961 gttgctaatc agttgcaggt atccagagcc aaagtacagg aggaaaagcc agtctttgca
     4021 gtagttgagc ctgccgttgt acctttgaaa ccttcaggta tgggactcaa aatttatatt
     4081 ttattatttg tgttcctgtc cgtatctggt actctcgtgt gggtgctttt tggcaaaagt
     4141 ctgctggcta gcttgagaaa agaactgaaa aataaggaga tagaacagga taaatgatgc
     4201 taaaacgtcg tttacaacat tcttacatca attaaattca cttactatat tattaaacga
     4261 atgatacgta cagctatgat aatggctgcg ggcatgggaa cccgttttgg ccaatataca
     4321 gaattgatac ctaaagggtt cgtcaaagtg ggaggtattc caatgatagt tcgttctatt
     4381 gatactttgt tatcatgtgg cattgagcga attgtaatcg gtacaggata taaacaagaa
     4441 gtttatgaag aattgaagac agactatcct atgcttgaaa cctgttttag tcctcgttat
     4501 gctgaaacaa atagtatgta tactttatat aatacgcggg agattctggg caatgatgat
     4561 tttttattgt tagagtcaga tttgattttt gagaaacaag caataatgag cttattggag
     4621 tgtcctgcgg cagatgcaat gctaataact ccagtgacaa agtttcaaga tcagtattat
     4681 gtggaacatg atgataattt tcgcctttct tcatgttctg tcaataagaa taaactaaac
     4741 gctaaaggcg aattggtcgg catccataaa ctatccggtt ccttttacaa aataatgtgt
     4801 gctgattatg cgagtattgt tgatgaacaa cccaatttgg gatatgagta tgaattacta
     4861 cgaatatctt gttctcaatc tcctgtttat gtgcataaag tagaagggct gaaatggtat
     4921 gaaatcgatg acatatcaga tttggaatat gcagagaaat atattgttcc gtattgttaa
     4981 ttaaaataat atatcaaatt atgagtaaga cagtttatat tgggatgact gcggatatta
     5041 tgcatccagg acttatccgc attattaatg aggctactaa atacggtgat gttataattg
     5101 gtcttcttac agataaagct attgcggagc ataaacgcct tccttatctg acctatgaac
     5161 aacgaaaaga ggtagttcag aatattaaag gcgtatgtaa agttgttcct caagaagaat
     5221 ggagctatgt tgagaatctc aaacgcatta aacctgacta tataattcat ggtgacgact
     5281 ggaaaaccgg gcctttacgt gaagaacgtg tgcgcgtatt tgaagtgatg aatgaacagg
     5341 gaggaaaggt tatcgaaatt ccatatactt tgggaattaa ttcatcttct ttggataaag
     5401 atattaaggc tataggtaca acccctgatg tacgtttaaa atcacttcgt cgtttgataa
     5461 atgccaaacc cgtagttcgt attttggaag ctcatgatgg actatgtggc ttgataattg
     5521 aaaatcagga aatattaaaa ggggataaga gggaagtatt tgacggaatg tggtctagta
     5581 gccttacgga ttcaaccagt aaaggtaaac ctgatattga ggcggttgat ttaactaccc
     5641 gattgcaaga tttgaataat attctggagt gtactactaa acctattatt tttgatggag
     5701 atacaggtgg taaaattgaa catttcgtat ttacagtacg cactttagaa cgtcatggaa
     5761 tctcagctat aataattgaa gataaagttg gattaaaaaa gaattcattg tttggtacgg
     5821 atgttattca aactcaagat acaatcgagg ttctgtaata agatcaaagc aggaaaggca
     5881 tctcagatta ctgatgattt tatgattatc gctcgtattg agagccttat agcgggaaag
     5941 ccggtaagtg atgctttaga gagagctttt gcatatgtcc aagcgggagc ggacggtatt
     6001 atgatacata gcaaaaataa gtcgggtgaa gatataaaag aattttgttt ggcgtttcga
     6061 aaacagtatg ctcatgtacc tatcgtggtt gtgcctacta catatgatca tatttatgag
     6121 tctgaattgt gtgattgggg tgtgaatata attatttatg ctaatcatat gcttcgtgcc
     6181 gcttatcctg ctatgatgaa tgtcgcaaag acaatattag agaatgaacg tgctttagag
     6241 gtgcgcgaac tgtgtatgcc cataaaggaa atattggaac tgattccggg tactaaataa
     6301 aaagaggaat atcattatgt taagcgtaga aaaagtttat gaaacgtttc tgagtcatga
     6361 cgttgatttt tttacaggag ttccagactc attactaaaa aatatttgtg cctatatcac
     6421 agaccatact tcacgtgaga aacatatcat agctgctaat gaaggtgcgg ctgtaggaat
     6481 tgcttcaggt tattatatgg catcaggtaa ggttcctgtg gtttatatgc aaaattccgg
     6541 cttgggtaat actgttaatc ctctgctgtc tcttgcagat gaacaagtat acagttttcc
     6601 aatgcttttg atgattggct ggcgtggtga accgggaaca aaagatgaac ctcagcataa
     6661 aaaacagggt gaggtaactt tagatttgtt gaaagcaatg cggattcctt atataattct
     6721 tgattcaaat gagaatgatg catttattca gctccatgat atcatacaat cagcaaaaac
     6781 taagaatatt cctcatgcaa taattattcg gaaagatgtt tttggcaaat ataaacttca
     6841 aaaagagttc ggatgtaatt atcctttatc tcgtgaggat gctttgcaaa tagttgtgga
     6901 ttatctgcct gaaaattcag tggtcgtttc tactactggc aagctttctc gtgagttatt
     6961 tgaatatcga gaaatgaaag agcaaggtca tgaacatgat tttctcacgg taggctctat
     7021 gggacatagt tcatcaatct ctttgggtat tgctatagca aagcaagata gacctgttta
     7081 ttgcttggat ggtgatggag catttattat gcatttaggg gcaattagta acattggcga
     7141 tttatctcct aaaaactatt atcatatttt gtttaacaat ggtgctcacg agtctgtagg
     7201 aggacagcct actttaggat ttagtttaga tattccggct attgtccggg ggagcggata
     7261 taagcatact tatactgttt gtacaaaagt tgaaattgaa gaagcaatga agcagcttcc
     7321 aaagttatgt ggtcctgttt tgttggaaat aaaggttaaa atagattctc gggagaattt
     7381 gggacgtccc acgactactc ctatagagaa taaggagcat tttatggatt ttttaaaata
     7441 aatatattcg atgaaaatag aaagaaaaat attattaaat cctgggcctg ccactactac
     7501 tgacagtgta aaaatggcac aagttgttcc ggatatttgt cctcgcgaga aagaattcgc
     7561 aggtatgatg aaacaacttc gggacgattt ggtcagagtt gctcatggga atttggaaaa
     7621 acataccgct gtattatttt gtggctcagg aaccatcaat attgatatat gtctaaattc
     7681 tcttcttcct gaagacaaaa gggtgcttat agtgaataat ggggcatata gtacccgtgc
     7741 tgtagaagtg tgtcaatatt atggtttgcc tcatattaat ttggaatttt ccgtttacga
     7801 acgtcctgat ttatcggtgg tggaaaatgt gttgcaagaa aatcctgata tagctatggt
     7861 ttatactact catcacgaga cgggtacagg aattctgaac cctattcgcg agatgggcgc
     7921 tatagctcat aaatatcagg ctaaatttgt cgtcgatact acttcttctt tgggcatgat
     7981 tccttttgat atagagaaag ataatgtgga tttttgtatg gcatctgctc aaaaaggact
     8041 tcaagcgatg acaggtcttt cttttattat aggcaatgag gaacagatta agttttcaaa
     8101 aaaatatccc aagcgttctt actattgtaa tctttatttg cagtatgaga attttgagag
     8161 aacaggtgaa atgcatttta ctccaccggt acaaactatt tacgccactc gtcaggcatt
     8221 aaatgaatat tttgaagtgg gcgaagaagc taagtttgcc cgtcacaaaa gagtttttga
     8281 ggctattcat tcaggtataa atgaaattgg tcttaaaagt gtaataaagc gtgaatggca
     8341 gtcaggactg gttgtctcag ttcaataccc agaagatccc aactgggatt ttgagaaaat
     8401 acatgattat tgttatgagc gtggatttac gatttatcca ggtaagatat caactgagga
     8461 tacttttaga gtctgtgctt taggagagat agaagtagat gatattgaga acttctttaa
     8521 agtactaaaa gctgcattaa atcattataa cgtcacatta ccgatgtcat gattgcagaa
     8581 atattattga agattcgtca tttttatttt tcccttcgtg gtatacactt ccatccggaa
     8641 agtgttattt ctggagtgcc tattcgtagc tttcgctagt aggcaaatat agcaatatct
     8701 acttaggtaa aaatgctgaa atacgttcag gctgttatct gattgctcgt gataaaatca
     8761 ttattggaga aaactcaaca ctcgcctatg gaacgactat attgacaact gctgatccta
     8821 atggaccgta taatgcatta gcagttcttt atccttataa aaaggcaccg gtagttatag
     8881 gagataatgt ttggattggg gctaatgtta ccatccttcc tggagtaact attggtgatt
     8941 acgttgtagt agcagctgga gctgttgtaa caaaagatgt accttcagga gtattggtag
     9001 ctggtgtacc agctattgtg aaaaaacgtt ttaataaatg aaagaaaaaa cttctttaaa
     9061 gaacaaagcc atatgtggaa tcttttggag tgcagttgaa cgatttttat cacaggggat
     9121 acagtttgta gttacagtca ttatggcgcg ttttctattg ccatctgatt atggaatggt
     9181 aggaatgtta gcaatagttc ttcaattatc tcaaacgtta atggatagtg gttttactaa
     9241 tgcccttatt cgttataagg aacgtactga aattgattat tcaacagttt tcttttttaa
     9301 tatattagca tcattagtta tttattttct aatttttttt ctagctcctt atatatcgtg
     9361 gttttataaa ataggtcaat tagttgagat tactagaatt ttatctattg ttattgtttt
     9421 aaattccttt gcgattattc ctaaaactaa attaataata gctgtagatt ttaaaactca
     9481 atcaaaagtc tcatttattg cagctttggt ttcaggtatt attggcattt gggctgcata
     9541 tttagatttt ggagtttggg ctttagttgg acaaacttta gtaaacggat tgttgattgt
     9601 agttttgtat gcatattttt gtagatggaa accattgtgg atattttcat tgaaatcgtt
     9661 tcgtttatta tttgcttttg ggtcaaaatt agtattagct aatattctta atactttata
     9721 taaaaatctg tatgctatag ttataggaaa gaagttttcg tcggttgatt taggatttta
     9781 tactcgtgcg gaacaatttg ctcagtttcc ttcatataat ttgagtgcaa taatttctag
     9841 agtgacatac cccatattga gccttgtgca aaatgataat gatagattat ctgctttata
     9901 taggaaatat gtccgtttat cttctgcttt tatctttcca ttgatgattt tgttaattgt
     9961 catagctcag ccactggtat tattgctttt gacagaaaaa tggataggag tagttgtatt
    10021 gcttcaaata ttgtgtttag attggatgtt tgatcatttg agtagtataa atttgaattt
    10081 actatatgta aagggacgtt cagacttggc tttacgttta gaagttataa aaaaagtgtt
    10141 agcgacgggg atccttcttc tatctattcc ttgggggatt gtaggtatgt gttgggggcg
    10201 tgttatgtat tcattgattg ctgtgtattt gaatacttat tatacagaat cattgattaa
    10261 attaagtctt attagacaga tgagagatat actaccaagc ttttttttag cattaataat
    10321 gggaggaggt acttggtata tgattttatt gttagagggt gaaattgttc aaattgtagt
    10381 aggaagtgtt attgctttat tgctatatgg aacgttgttg tattgctttt ctcgatcctt
    10441 gtttgatgaa atatgggcgg ttatattaaa aataaaaagg taatggataa actgagtttg
    10501 attattagta aaatacgacg gaatcattgg tatagaacct atatgcgtcc tatatattta
    10561 tttgtttatg gcaatagaaa attgaagaat agaaatagaa tatttttgca gtattcacaa
    10621 gagctgctaa ctaactttca tcaagcaatg aatgaagtgg gaattcctta ttggttagaa
    10681 tttggaactc ttttaggtgc tgttagagaa cacagtttta taagtcatga ttttgatctt
    10741 gatgtgggcc tttttaagga agattattca gatataataa gagaggtctt aaaaaaatat
    10801 ggtttcaaaa gaataaggtg tataaccgcc cttgatttta ttgatgctta tgaggaaact
    10861 tatctttata aaggtgtgac aattgatctt ttcctttttt caagagagaa aaattgtgat
    10921 ggggtctatt gttatgattt tgttccagta tattcagata taaagagaac taaaaaaggt
    10981 gataatgcaa tccggagaat tcattttcct agaattgatt tgattgaata ttcatttatt
    11041 ggaattaata cttttgttcc tgaaaattat gaggaacatc tttgtatgca ttatggtaaa
    11101 gactatatga ttccaaatcc tcattggaaa gattcagatg cgcaacatac tgatatcttt
    11161 tatggtagag agattagaat tgaattgttt gataaaagta aataatagta gataatacat
    11221 gttctatcta ttttttttac taattgtgct atttttgtta tatatacaaa gtaggaaaag
    11281 acaatattct actgtagcgg gaatttgtgt tgtgctattt ttgttatata tacaaagtag
    11341 gaaaagacaa tattctactg tagcgggaat ttgtgttcct attattataa tttttgttgt
    11401 aatttgtcgt tatagagtgg ggtatgacta tttaacgtat tatacattaa ttgaaaatga
    11461 agaagaggca cagattttat acttattttc tcctttaagc attgtttggg cagagattgc
    11521 tttatatttt gaatctccac agatgttatt tgttcttttt gggcttccaa catttgctct
    11581 tctaatattt actttaaaaa aatattcaaa agattatgcg ttatcagtaa ctattttaat
    11641 ttgtttcttc ttttttacat cactcagtat tattcgacaa gctttggctt tggctatttg
    11701 tttttatggt tatcgtttta tagtaaaacg ttcactaatt aaatatatat tatgtatatt
    11761 gattgcagct ttattccatc cttctgcagg agtagcgatt attatatatt ggttgccatt
    11821 tctaaagttt agattagttg ttacttatta tctataatat caatagtagc caaaccttta
    11881 ttttttatat gctaaatata ttaggggtgt atacctctta tcttgatggc aagatggata
    11941 ttgaaggtgg gaaatatact caattaatat ac
//
