LOCUS       c00029_gnlPro..        16057 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CCBCIBCO_29.
ACCESSION   c00029_gnlPro..
VERSION     c00029_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:40:27
            Original ID  :: gnl|Prokka|CCBCIBCO_29
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16057
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16057
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3245:6057]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3246..6057
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16057
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16057
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..95
                     /locus_tag="ctg29_1"
                     /transl_table=11
                     /translation="PFTPGCTGSLHPDVKDGNMGVFTELSACFC"
     CDS             complement(526..2076)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_2"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.9e-48, bitscore:
                     156.1, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDQLSGIFSGLVSQYVFDIQVAPDHESRQELIDLLGDVASCSDH
                     LSCSVADGEGLQFTIVKDGMPTGIRFRAVPNGHEFTSLLLAVLNSDGKGKNIPDESICA
                     RVRALNGPIKLTTYVSLTCTNCPDVVQALNVMATLNSRITHETVDGAINQKEVEAMKVQ
                     GVPSVFADGKLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKTVKNYDVIVVGGGPAG
                     AASAIYSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGKQLANDLLTHINDYPVD
                     ILEHRRVDKVELDGSAKLLTTSTGERFSAPALIVATGASWRKLNVPGEADYIGKGVAFC
                     PHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEKAKSLP
                     NVEVFLHSQSLEVVGDGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLAANSGVFRDVVE
                     TNKPGEIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSAFEDRMRGSIG"
     CDS             complement(2096..2662)
                     /locus_tag="ctg29_3"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             complement(3246..3896)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 57.5;
                     E-value: 5.9e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.1e-34, bitscore:
                     111.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQGCPLRCLYCHNPDTWEVKSGTPYRMEPEALLAEVLRYKNFIAK
                     GGVTVTGGEPLLQPEFLKEFFRLCRENGIHTALDTSGYICSGKALEVLEQVDLVLLDIK
                     TIDAGLHPRLTAVKLDNTLRFLDELEKRGIPVWIRHVIVPGLTDDDEALSKLAEYISSY
                     NVVQKAELLPYHTMGAYKYEAQGLDYKLKGVEPLSAERLANAKAIFMKHGVTV"
     CDS             complement(3985..6057)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_5"
                     /sec_met_domain="Gly_radical (E-value: 4.4e-46, bitscore:
                     146.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3e-264, bitscore:
                     868.9, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKVEREKGVYDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPL
                     KRGIFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTDEMIAARRSAI
                     ITGLPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQKRLDIQELTEEIIQSREEITEQI
                     KALKAFEKMCAGYGFDVTRPAKDAREAVQFLYLAYLAAVKDQDGAAMSLGRTSTFLDIY
                     IEKDICEGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDG
                     RSLVTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPDNWKNFCAKVSIDTSAIQYENDDL
                     MRPDYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDEKSGVQVAPRFEP
                     ITSEYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMGLHDGDVERIRA
                     TGIAGLSIVADSLAAIRDTKVKVIRDERGLAIDFEREGEYVPFGNNDDRTDSIAVDITE
                     KFMEYLRQHQTYRKATPTQSILTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDT
                     KGAVAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQINNLVSLLDGYFTPDGGQH
                     LNVNVFDRDLLLDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINSSL"
     CDS             complement(6653..9754)
                     /locus_tag="ctg29_6"
                     /transl_table=11
                     /translation="MNKKFSTLMAGFLLTSAFASAQVTLDPANLKIAEKVEPGKEYLVI
                     QSADNKIDGEDRVLSVVADEEGNLTYKAYKLSSYDGEKTETATSEKSNLLWVLGEAKIG
                     LGTTKSYYTLKNSEAGSYLSFDKSKKLIKTVADSKDALNGVGTDGKAKDVYSYFINAVT
                     ADKSSILKQGDYLYSENGVYRAHQLQFGSKALVSLNGQDDDAKLYFCVYNTIEADLDDI
                     IEMNKTMGGEGFNLNFTNDKLKDCEENVIYEQKFKAFYVKNELEVDLGDKGVTHVIPAG
                     FYLATSYPETLIGTAEIKDAKDFLACSFLAVSPTENDKINGLAPKDGKGFKLAIVKAED
                     MNYVEDFDLDQAAVKGQTYVGNACFTIEIPDFANNEEAYQFKAKDIRVWVDGELAKADD
                     MYISSVTSEGKSRVVTNDSGVTFETDNSSILNPKKLLSTEDRPSIFTIQFVSGENKEEN
                     SEYGQYLTVGNQTASGKFTFFSTTDENVGSDPLYQFVIADIDTVKHTITFANRQTKKTL
                     TASLYTEDADNMIYTIYAENVKYQQENVTDKSNEKVKFDSKALSVKKIQLAPVTVEDKF
                     ATFNAAESINGLVRFELARTSEADAKFFVYAPRKKKANGDVVLNPGAGNVMVVTEDVAD
                     QFELVKVLKANGKPDTQYSELSYVFNKDGKKYTSLKRDTVAYDTYNIKLFAPEEAEAYY
                     INGTSLIKGQATDENATFVIKTNLDGSVSLIYDNDLKNDANYLEFADAKKEKEAAWTSG
                     NYYNFGETFNKVKTFMVAEPEAISLEAKPQHLSIEAVRGGFISMNANKDGILAMNNTDT
                     EAMTLWVDTVKSDEAVPSFYIAKGGNFLYFAKDSAESSLVNKDSYKLEDKNYKLIFKAA
                     ELVSSDTLKTVVDGKEALVAAKANAGKKIKGGLGNFQYQIIKDEEGSDEYVIRLTDVYN
                     YVRVINNMLTLDADKKKAARFTIESQEAPTANEGVAVSEVKVLAGEGNVTIAGAAGKKV
                     VISNILGQVVANTVISSDNATIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             complement(11688..11999)
                     /locus_tag="ctg29_7"
                     /transl_table=11
                     /translation="LTERTEHFDTVFVPGRRKDGRFAFRTRSSEEVDRLMMLVGQTDRD
                     DQMTGTDIEGRMDKTCDVELFQSNFTAFFNFHFVFSVFCVFYLIGTSRTSSLKFYFCS"
     CDS             complement(12150..12548)
                     /locus_tag="ctg29_8"
                     /transl_table=11
                     /translation="VLAFAFFLWVVVFVADERIDYGYAHIVFTNRTQVEPHFTTVADRT
                     FGDRGCLCIRRTAALVVVDTAEGVGFAQVAVYHVCACGDIFVFVLQVSRIDAQRYVSIF
                     DVCFWFVGIGSRIVAIVEGTAYFQSRYS"
     CDS             12762..13814
                     /locus_tag="ctg29_9"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNNDPNPDGGGKDPVNLDYSS
                     ENASAWGNYMYNVAMLLNDDATMLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKLIASTNPDLDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEVKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAVVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EASLSARLPT"
     CDS             13769..14026
                     /locus_tag="ctg29_10"
                     /transl_table=11
                     /translation="VGKERSFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEW
                     SGNFDEEDEAIGAAQSVRGYHTLEYLLFKDGQPRTVDGAK"
     CDS             complement(14117..14323)
                     /locus_tag="ctg29_11"
                     /transl_table=11
                     /translation="MSLGKSLKSLLTAHIRSGHLFYPYPFYRPLHKLRMQRAGVARMLT
                     GKIASYHFIGFLNLFPNNASRIV"
     CDS             14509..15606
                     /locus_tag="ctg29_12"
                     /transl_table=11
                     /translation="LWENGGSGNYGFSSMLVYISRRNGAFFRDYGRVLHDQAIYGVKPE
                     GKLSVTYDKQTFSFPDGETYELCKPNYTITEWYKDSIAPEDLFCTVRIPLRHVGMGQMM
                     AIDRREIEALAAKSNYPEYGISGRCNYITEKGVTGVGLSGNKAQHLDLTVELGFSSDMG
                     VTNSRYPEEICEGQAQINQGSMMGLSYDQLDISTADMEDVDLYMQSLGVPARRNTNDPQ
                     VILGEQKFYEAKCHLCHVTTLHTQAGGSTLLNGTRLPWLGGQTIHPYSDFLLHDMGSEI
                     MGVGLNDNYVSGLARGNEWRTTPLWGIGLQEKVNGHTYFLHDGRARNLTEAIMWHGGEG
                     EASKNLFKQMSKEEREAVIAFLNSL"
     CDS             complement(15725..15982)
                     /locus_tag="ctg29_13"
                     /transl_table=11
                     /translation="LEDVSSASGGIDGEVECHPVECLARETEDGVGDRETAVVYIVLIV
                     GRVQPFIVVVVDVSTGLDQHIRFENEIPLLGSDCKTFFAV"
ORIGIN
        1 ccccttttac acccggatgt accggctctc tacacccgga tgttaaagat ggcaacatgg
       61 gggtgtttac ggaattatct gcttgtttct gctaaaaaaa gagagggctt ttgtggaatg
      121 aagaaccgta tttcgtcaat ttaacaccta ttgcattcgt ttttacattt gtttattcga
      181 ttattttata tgctttttca aaggcaaaag aaggcaatat attggtttcc aatcatatga
      241 taaaaacgtc ctgttagagg agtgatagag gcagtgatac aggatgtttt cctctatcac
      301 tcatctaacg cttgaatatt aatagctaca accttcgtag tgatagagtg atagaggatt
      361 tgtagaaact tcgtatggag atcacaacct tggaaaattt tgatgcggtt gccctgttgt
      421 gaaagtcggg gctttgtgcg taaaaaagaa aaggtgtgca attttgaaca cacattcgtg
      481 tagttcaatt tgcacacctt cgtcgttcat agcaaatact aaatattaac cgattgaacc
      541 tctcatgcgg tcttcaaaag cagatagagc cgcttttgcc ccttctccca ttgctatgat
      601 tatctgttta tagggtacgg tcgagacgtc gcccgccgca tagatgccgg gaacattcgt
      661 ccgacaatgc gcatcgatta caatctcacc cggtttgttc gtttcgacaa cgtcgcggaa
      721 aacgccacta ttggctgcca agccgatttg gacaaagatt ccgtccaggt cgatcacccg
      781 ctccgcatcc gtcttacggt cttttacacg aagacctgtt accttatcac cgtcaccaac
      841 cacttccaaa gattgggaat gcaagaaaac ttccacattc ggcaagctct ttgctttttc
      901 ctgcaacact tggtcggctt tcagttcgtc cataaattcc agaaccgtca ctttcgaaca
      961 aatgcctgcc aaatctatag ccgcttcgat acccgaattt ccaccgccga caaccgctac
     1021 gtgcttacct ttatagaacg gaccatcgca gtgagggcaa aaagcgacac cttttccgat
     1081 atagtccgct tcgcccggaa cattcaactt gcgccagctt gcacctgtcg ccacgataag
     1141 ggcaggagca gaaaaacgtt caccggtaga agtggtcaga agtttcgccg atccatccag
     1201 ttcgacttta tccacacggc gatgctccag tatatcgacc ggatagtcgt tgatatgtgt
     1261 caaaaggtcg ttcgccaact gctttccagt agtctgagga acggaaatca ggttctcgat
     1321 accgaccgtt tctttgacct gtcctccgat acgttcggct atcacagcaa cattcaagcc
     1381 tttacgtgcc gagtagatgg cagaagcagc accggcaggt ccacctccca ctactatcac
     1441 atcatagttc ttaacagttt tttcaacaga gttatcaaca cccccttcat taattccgta
     1501 ttgggcttcg agtttggaaa gcaattctcc caaatcacta cgccccacat tgatcagttt
     1561 gccatcggca aaaacagaag ggactccctg tactttcatt gcctcaactt ctttttggtt
     1621 gatagcgcca tccaccgttt cgtgggtgat ccggctattg agagtagcca tgacattgag
     1681 tgcctgcact acatccggac aattggtgca agtaagagaa acataagtcg tcagcttgat
     1741 cggaccattc aaggctctga cacgagcaca gatactttcg tccggtatat ttttaccttt
     1801 tccatcacta ttcaggacag ctaacaacaa ggatgtaaac tcatgtccgt taggtactgc
     1861 acgaaaccgg ataccggtag gcataccgtc ttttacaatt gtaaactgaa gtccttcgcc
     1921 atccgcaacg ctgcatgaca aatgatccga gcatgatgcc acatcaccaa gcaggtctat
     1981 tagctcctga cggctttcgt gatcgggagc gacttgtata tcaaatacat attgggatac
     2041 cagtccggag aaaatacccg aaagctggtc tttcattgct gagtctaaca taactttaga
     2101 tcttaccaac caagtcgatg ctcggcttca aggttgcttc gccttttttc cactttgcag
     2161 gacaaacttc gttcgggtga gaagcaacga actgggcagc ttcaacttta cgaagcaatt
     2221 cgtctgcatt acggccgata ccgttatcgt ggatttcggc aatcttgatc tttccctcgg
     2281 gatttaccag gaacgtaccg cgataagcca tcccctcttc ttcaatcatc acaccgaatg
     2341 cacggcttaa agcccctgtc gggtctgcca gcatcggata tttgatctta cggatcgttt
     2401 cggaagcatc atgccatgct ttgtgtacaa agtgcgagtc tgtacttacg gaatatactt
     2461 cgacacccat ctcctgaaat ttgccgtact tgtcagccat atcgaccaat tcggtcggac
     2521 atacgaacgt aaagtcggca ggatagaaga aaaagatggc ccatttgccc ttgatatctt
     2581 cgctacttac tgtcttgaaa ctaccattct gaaaagcttg aactttgaat tcgggtactt
     2641 gtgaattgat aattggttcc atgattttta ctatttaatt tgttactact atttttgttt
     2701 accctacaaa ggtaaatcgt aagatactga ttgaaagaat ttttcaaatt gataattttt
     2761 atctgccgat agacggattt ctatctgcaa gcatacttat ctactatgac aataggaagc
     2821 aaagtaatgt tttccggaac aataaaaata tacctaattg taggtaaaat acctttcgat
     2881 cataccatgt gattctttaa ttgttaactt tggatgttaa cttaaaaata ttcgaagaag
     2941 agaagagcta gtttgtataa tacattttca gcaagtctat tgctcgtttg caacgcatgt
     3001 ctttcttcat gtgtctcaca aatacccctt acaaaggaaa aaccggtaaa caattccact
     3061 tatcaagtcg aatatctgtt cgaacacgaa gggtgtaagg tctatcgttt catggatatg
     3121 ggacattaca tctatttcac caactgcgag ggagatgtta ccagtattga aagcgacagc
     3181 gtccgcacag tcaaccggat cagccgtaaa ccgatcatca tcaaagagca gacactcgat
     3241 taggcttata cggttactcc gtgtttcata aagatcgctt tcgcattggc cagacgttct
     3301 gctgaaagcg gttccacacc tttcagctta tagtccaggc cttgtgcctc atatttgtaa
     3361 gctcccattg tatgataagg cagaagttcg gctttctgga ccacgttata tgaactgata
     3421 tattcggcca gcttgctcaa ggcttcatca tcgtccgtca ggccgggcac gatcacgtgg
     3481 cgaatccata cagggatgcc gcgtttctcc agttcatcaa gaaagcgtaa agtattatcg
     3541 agttttacgg ccgtcaaacg gggatgaaga ccggcgtcga tcgtcttgat atctaacaga
     3601 accagatcga cctgttcgag cacctccaat gctttaccgg aacagatata gccggaagtg
     3661 tccaacgccg tatgaatacc gttctcacgg caaaggcgga aaaactcttt aaggaattca
     3721 ggttgtaaca aaggctcacc accggtcacg gtaacaccac ctttagcgat aaaattctta
     3781 tagcgcagca cttcggcaag caaggcttcc ggttccattc gataaggcgt cccgcttttt
     3841 acctcccaag tatccggatt gtggcaatac agacaacgaa gcggacatcc ctgcatgaaa
     3901 acaacaaagc gaattccggg accgtcaacg gtcccgaaac tctctaaaga atgtatacgc
     3961 cccaacatat taatcaatgg acaattataa actgctgttg atggtgcgcg agatgacgtc
     4021 gagctgctgt tcgcgtgtca gcttcacgaa gttgacggca tagcccgaaa cgcggatcgt
     4081 aagctgcggg tatttctccg gatgctccat tgcatctaac aacaagtccc tatcgaacac
     4141 gttcacattc agatgctggc caccgtcagg cgtaaaatag ccatccaaca ggctcaccaa
     4201 attatttatc tgaatatcgc gctccttacc caatgtagcc ggtgaaacgg caaatgtata
     4261 ggagataccg tcatgcgcat gctggaaagg cagtttggca acagaagcca aagcggcgac
     4321 agcccctttc gtgtcgcgtc cgttcatcgg gttggctccc ggagcgaacg gcgtaccgcc
     4381 cggacggccg tcgggagtcg ttccggtttt ctttccgtaa accacgtttg atgtgatcgt
     4441 caggatagat tgtgtcggag ttgccttgcg gtatgtctga tgctggcgca gatattccat
     4501 gaacttctcg gtaatgtcga cagcaatact gtccgtgcgg tcgtcattgt ttccgaaagg
     4561 tacatattcg ccttcgcgtt cgaagtcgat agccaaacca cgttcgtcac ggatcacttt
     4621 cactttcgtg tcacggatgg cagccagcga gtcggcaacg atagaaaggc cggcgatacc
     4681 ggttgcgcgg atacgttcca catctccgtc atgaagcccc atctcaaaag cttcatacgc
     4741 atatttgtcg tgcatgtagt gaatgatctt cagagcattg acataaactt ttgccaacca
     4801 gcgcatcatc tgctcgtatt tctccatcac ttcgttgtaa tccagatact cgctggtgat
     4861 cggttcgaaa cggggagcca cctgcacacc cgatttctcg tcacgtccgc cattgatcgc
     4921 atacaacaag cactttgcca ggttggcacg agctccgaaa tactgcatct gcttaccgat
     4981 cttcatcgga gacacacagc aggcgatacc gtaatcgtcg ccatagtccg gacgcatcag
     5041 atcgtcgttc tcgtactgga tggcagaggt atcgatcgat acttttgcgc agaagttttt
     5101 ccagttatcc ggagcattgt tgaaccaaag caccgtcagg ttgggttcgg gtgccgggcc
     5161 gaggttatac aaggtatgca gataacggta agatgtcttt gtcaccagcg aacggccgtc
     5221 aacaccttgt ccgcccagcg attcagtcac ccaaacaggg tcgccggaga acaggtcgtt
     5281 gtattccgga gtacgcagga aacggacaat acgcagtttg ataataaact ggtcgatcaa
     5341 ttcctgtgcc tcttcttccg tcagcttgcc ttcgcaaata tctttttcga tatagatatc
     5401 gaggaaagta gaagtacgtc cgagagacat ggctgctcca tcctgatcct ttacggctgc
     5461 caggtaagcc agatacaaga actgcacggc ttcgcgggca tcctttgccg gacgtgtcac
     5521 atcgaaacca taaccggcac acattttctc aaatgctttc agcgctttga tctgctccgt
     5581 tatctcctca cggctctgaa tgatttcttc tgtcagttcc tgtatatcga gacgtttctg
     5641 gaaacgtttc ttttcttcga tcaggatctg ggttccgtac agaggtacac gacggtaatc
     5701 accgatgata cgtccgcgtc cgtaggcatc aggcaacccg gtaatgatgg cggaacgacg
     5761 tgccgcaatc atctcgtctg tataggctga aaaaacgcct tcgttgtgcg tctttctgta
     5821 tttggtgaag atctcttttg tcatcgggtc cagatgatag ccataggctt ccagactgtt
     5881 ttcgaccatg cggataccgc ctttcgggaa gataccgcgt ttcaacgggg catctgtctg
     5941 caagccgacg attacttcgt tttccttatc gatgtaaccg ggtccgtatg tgtcaatccc
     6001 ctggggaagc ttcgtttcgg catcatatac tcctttctcc ctttcaacct taaacatctc
     6061 ggttagtttg ttccacactt ttttcgtttt ctccgaagag ggtacgagga acgtatcgtc
     6121 tccgttataa ggtttgtaat tgttctggat aaagtctctt acattgatct cctttttcca
     6181 ggtttctcct ttgaactgcg cccagttctc gttttcaaac ttcataagct tatcttgtct
     6241 atttcggttt aggcgtgcaa agatacgtct tttcccccta tctgaaaagg atcgtaaagg
     6301 acgagggatg ttaaactggg gaaaatacct acaaataggg ataagggaaa taaaaacgaa
     6361 gccccggcag tacgaatacc gccggggcct gttttttgtc tgccgtccgg tcttcacaga
     6421 gggaaaagca gtagaacttt taatttcatt actttagtat tattaatatt aaatccaacc
     6481 gctcgttcgc ctgtcgcagg gtaattgaaa ccgtagatca agaaaacctc ttacatacgg
     6541 tttcacgcag gttgtctaga attatttgat tataaaatgt cattgtgcct gtgtaagggt
     6601 ggttcactaa ccacccttac gatagacagt attgtttttt tagtatcaat cgttacttaa
     6661 cgatagcttt tacagcagct tcgccttcaa cagctacaac tactacaccc gccggagcag
     6721 cgatagttgc gttgtcagaa gagattactg tgttagctac tacctggcct aagatgttgc
     6781 tgataacaac tttcttaccg gcagcgcctg cgattgttac attgccttcg ccggcgagaa
     6841 ctttcacttc agatacggct acgccttcgt tggctgtcgg agcttcctga gattcgatcg
     6901 tgaagcgagc ggccttcttc ttgtctgcat ccagtgtcag catgttgttg atgacacgta
     6961 cataattata aacgtcagtc aggcgaatca catattcgtc gctaccttct tcgtccttaa
     7021 tgatctgata ctggaagtta cccaaaccac ccttgatttt cttgccggca ttagccttag
     7081 cagcaaccaa tgcttccttg ccgtcaacga cagtcttcag cgtatcggaa gaaaccaatt
     7141 cggcagcttt gaagattaac ttatagtttt tatcttctaa cttgtagctg tccttgttta
     7201 ccaacgaact ttcagcagag tcttttgcga aatacaagaa attgccaccc tttgcgatat
     7261 agaatgaagg aacagcttcg tctgatttca cagtatcaac ccacaatgtc atcgcttctg
     7321 tatctgtatt gttcattgcc aagataccat ctttgtttgc attcattgaa atgaatccgc
     7381 cacgaacagc ttcaatagag aggtgttgcg gtttagcttc caaactgata gcttccggtt
     7441 ctgcaaccat gaaagtcttt accttgttga aagtttcgcc gaagttgtaa tagttaccag
     7501 atgtccaagc tgcctctttt tctttctttg catccgcaaa ttccaaataa ttagcatcat
     7561 tcttcaaatc attgtcatag atcaacgaaa cggatccatc cagatttgtc ttgatcacga
     7621 aagttgcatt ctcatctgtt gcctgtcctt ttatcagact tgtaccattg atgtaataag
     7681 cttctgcttc ttccggagcg aataacttga tattatatgt gtcataagca accgtgtcac
     7741 gtttcaaaga agtatatttt ttaccatctt tgttaaatac ataagagagt tcgctgtatt
     7801 gagtatcagg cttgccattt gcttttaata ctttaactaa ttcaaactga tcggcaacat
     7861 cttcggtaac aaccatgaca ttccccgctc ccggattaag aactacatca ccattagcct
     7921 ttttctttct cggagcatat acgaagaact tagcgtcagc ttcacttgtt cttgccaatt
     7981 cgaaacgaac taaaccgttg attgattcag cagcgttgaa agtcgcgaac ttgtcttcta
     8041 ctgtcacagg agctaattga attttcttta cgctcagagc cttactgtcg aatttgactt
     8101 tttcattact cttatccgtt acattttcct gctggtattt cacgttttca gcatagattg
     8161 tatagatcat attatcagca tcttcagtat acaaagaagc tgtcaacgtc tttttagtct
     8221 gacggtttgc aaacgtaatc gtgtgtttta ccgtatcgat atcagcaata acaaactgat
     8281 acaacgggtc gcttcctaca ttttcatccg ttgtcgagaa gaatgtgaat ttaccacttg
     8341 cagtctgatt tccgactgtc aggtactgac catactcgct gttttcttct ttattctcac
     8401 cacttacaaa ttggattgta aagatagaag gtctatcttc cgtactcaac agttttttcg
     8461 gattcagaat tgaagaattg tctgtttcga atgttacacc agaatcattg gttacaacac
     8521 gagacttgcc ttcagatgta acagaagaga tatacatgtc gtcagctttc gccaattctc
     8581 catctaccca aacacggata tctttagctt tgaactggta agcttcttcg ttgttcgcaa
     8641 aatcaggaat ttcgatagtg aaacaagcat tacccacata agtctgtcct tttacggctg
     8701 cctggtccaa gtcgaaatct tccacatagt tcatatcttc agctttgaca atagccaatt
     8761 tgaaaccctt gccatctttc ggagccaaac cattaatctt gtcgttttca gtcgggctaa
     8821 cagctaagaa agagcaagcc aagaaatctt ttgcatcttt gatttcagct gtgccaatca
     8881 atgtttcagg ataagaggtt gccaaataga aaccagccgg tatcacgtgg gtaacacctt
     8941 tatctcctaa atccacttct aattcatttt taacatagaa agccttgaac ttctgttcgt
     9001 aaattacgtt ttcttcgcaa tctttcagtt tgtcattcgt gaaattcaag ttgaagcctt
     9061 cgcctcccat tgttttgttc atctcaatga tgtcatcgag gtcggcttcg atggtgttgt
     9121 aaacacagaa atacaatttg gcatcatcat cctgaccgtt cagacttacc aatgctttac
     9181 ttccgaactg taactggtga gcacgatata ctccattttc agaatacaaa taatcacctt
     9241 gcttcaggat ggaactctta tctgctgtca ctgcattgat aaaataacta tatacatcct
     9301 ttgcttttcc atccgtaccg acaccgttca gagcgtcttt agaatccgcc actgtcttga
     9361 ttaatttttt actcttatca aaagacaaat aggagccagc ctcactgttt tttaatgtgt
     9421 aataagactt cgtcgtaccc aaaccgattt tggcctctcc caaaacccaa agcaagttgg
     9481 atttttcaga agtagccgtt tctgtcttct ctccatcata cgagctcaat ttgtaggctt
     9541 tgtaagtcaa attgccttct tcatctgcca caacagacaa tacacggtct tcaccatcaa
     9601 ttttattatc cgcgctttgg ataacgagat actccttccc gggttctact ttttccgcaa
     9661 tttttaagtt tgcaggatcc aatgttacct gagcagaagc gaatgcactt gtcagcagga
     9721 accctgccat cagagtagaa aacttcttgt tcataatcta aaatgtttaa ttaataataa
     9781 tatgtatatt gaatatcgtt cttacttcct gtttaacagg tttttaccaa attcctgtat
     9841 tttgacgaga taaaacgtac gtttttttta gtcatttttg aggggctttc tggagggttt
     9901 gtgttggaaa gctggttttt cgtacttgtt aagctatctg attgataaga aagaatatag
     9961 aaaaggaaaa ataattggaa gaaaggattg caggtttaaa aagtagttgt atttttgtgc
    10021 agtgaaaatg gcgaacaaaa acgtacgttt tttcaccatt tttcttctca tacacctata
    10081 cttcttatta acaacaattt atagcaccca aaagtagcta aagccatata taaaagtaac
    10141 tgttttcaat cattcgccaa acctctttac atcttcatta aaacaaagat tatcagccac
    10201 atacaagaca aacatccttt actcgcatcg gaagaaaaaa atggcaaaaa caactggttt
    10261 cgtaatttcc tcttggagaa gcgtcccctt ttgttaaaga tatacaaaat acggagatat
    10321 cgattgcttg ctcaataacg gtttcaagac ttgcaaaacc ttacattatt atgtatcttt
    10381 acatcaacgt ccgttacaga cggatcaaac aactataata cattaatata atatataaaa
    10441 atcgatgctt ctgacatccc cgcctcctat ctgttctgta tgaaataaga cagctccaaa
    10501 gtcaccactt gcttgagaag gatcgcagaa caacagatcg gcgacgaggt gaaactgtgg
    10561 cacgtcatca gccctaaata ccaagagaaa caaaccgacc agtgttcatg cctatgtaac
    10621 gaccgtttca tgccgaggaa acggttgtgc caagccgatg taattgtttt ggcacagccg
    10681 aagtagcaaa catacccttg cgggaacaag tccaagactc gacgccgaac agattccgga
    10741 cagaagctaa tgggaaacgg aaacataaaa aagaagcctc tcttcacaga gaggcttctt
    10801 ttttatatcg aaaataacca ataaaaactt tccgatatag ttaatcatct tatatgctta
    10861 cataaatagc aaaaggtttt gatatagcga ttatactaat agtgttactt tcttaatgac
    10921 attgcaaaga tacgggtacc tccggcctcc tacaatacct atatgtgagt aaaaaaacgc
    10981 ctcttgctac ctaatcaggg tgatattgaa acaaaaagaa ccgtttttct caaaacagtt
    11041 cttcttttgt cgcaaggaaa accaataaaa atccccgctg ttgttattta ctttaaaata
    11101 aacattacat tgacattcta tcaataaggt tccggtcgac gattatacct aatcatgata
    11161 cataattgac aaaagcaaag atatgagtgg acaatcatta acacaatacc tacaaatatg
    11221 tatatttgtc tttaccctcc ccaattgtag ggatttcatg atatttttcc tgtaaaaacg
    11281 cacacaatac ctacaaatag gtaacatcga caccttttta cctactaatt gcgattgcac
    11341 accgttgaca gcccttctaa ttttgccaaa aattaaaaaa cgcaatgaaa aggttaacta
    11401 atttattagc aatcactcta ctaacctctt gtgtaacggc atttgcacag gaacaagaag
    11461 aaacaacgac agaaaaatcc gcagtggaac aatccgcaga catttatgca gccggatata
    11521 acaagttccg cttcggcgga tatggggaga tcctcgcaaa ctttatggac tacggcatca
    11581 atcgtttccg aggtacggac aacggaagca agaaagacca tcgcaattcg atctccatac
    11641 cccgttttgt cttggctttc gattacaaat tcaattccca atgggtatta ggagcagaaa
    11701 tagaatttga ggctggaggt acgggaagtg cctatgagat agaaaacaca gaaaacggag
    11761 aatacgaaat ggaagttgaa aaaggcggtg aagttgcttt ggaacaattc cacatcacac
    11821 gtcttatcca tccggccttc aatgtccgtg ccggtcattt gatcgtcccg gtcggtttga
    11881 ccaacgagca tcatgagccg atcaacttct tcggaacttc tcgtccggaa ggcgaaacga
    11941 ccatccttcc ttctacctgg cacgaaaacg gtatcgaagt gttcggtacg ttcggtcaag
    12001 gctacacacg tttcaactac caggctttgg tcgttgccgg attgaacgcc aacggtttcg
    12061 accgcaacac atgggttgcc ggcggcaagc agggactatt cgaaacagat aacttcacct
    12121 caccgggcta tgtggcccgc ctgaactatt taggagtacc gggattgaaa ataggcggtt
    12181 ccttctacta ttgccacaat acgggagcca attccgacaa accagaaaca tacgtcaaat
    12241 atggaaacat acctttgcgc atctatacgg ctgacctgca atacaaaaac aaatatgtca
    12301 ccgcacgcgc aaacatgata tacggcaacc tgagcaaagc cgacgccctc agcagtgtca
    12361 acaaccacca aagcggcggt tctccttata cacagacaac cccgatcgcc aaacgtgcgg
    12421 tcagctacgg tggtgaagtg gggttcaacc tgcgtgcggt ttgtaaagac aatatgagcg
    12481 tacccgtaat ctatccgttc gtccgctacg aatactacaa cccacaggaa aaaggcgaag
    12541 gcaagcacac gatggattta cgcaacaaag taagcatgtg gacagccgga gccaattggt
    12601 atgctttacc taatcttgtc gtgaaagcag actatacaac acgcaaaatc ggaggcggca
    12661 aatataacag cgaaaacgaa ttcagcttgg ctatcgccta tatcggctgg ttcctcagca
    12721 aataaaaaca atataaacaa attaataact tatcaataaa aatgaaaaag aaaaattatt
    12781 tctatctggc agccttatcg ctcgccatga cattctcgat gggagcatgt agcgacaaca
    12841 acgaccccaa tccggatggt ggcggaaaag atccggtcaa cctggattac agttctgaaa
    12901 acgccagtgc atggggtaac tatatgtata acgttgcaat gttgctgaac gacgatgcaa
    12961 ccatgctcta caattcttgg gtaaccgact acgtcgatga gcagggttca cacggcccat
    13021 atgccacgat cttcaaagac cagactgccg gagcttacca aagcccgctc tcgtgtatcg
    13081 aggaaatgat cgaaagcggt atgtggaaca tcgccaacga agtaggtgac gccaagatca
    13141 aagacccgta taccaaatac accagcggtg acaaggaagg cggtctctat gccgtcgaat
    13201 catggtatag ctggcattcg cgcgacgact atacgaacaa tatcttctcc atccgtaaca
    13261 catactacgg ccgcatcgac gacaacgacg tgtctaaagt ggacggaaac ctgagtgcat
    13321 tcaactctta caaggatttc gacgatgaag gagacatcgc agaacactcg ctttcaaaac
    13381 tgatcgcttc aaccaacccg gatctcgacg aagaaatcaa aacgctgatt ttcgcttctg
    13441 caaaggcgat tcaggctatt ccgcaaccgt tccgcaacaa catcgacagc gaagagtccg
    13501 ttgccgcaat gaacacttgc atggaactgg ccaacctgtt gttaaatgaa gtaaaaccgt
    13561 atgtaaacca aacattcggc gatcctgaat acgacgatga ccttgatgca atagccgaac
    13621 agtttgtcga tgcggtcgtt cttcctacgt ataaagactt gcaggaaaag aacaagcttt
    13681 tgctggatgc ggtaaaccag ttcagacaaa acccaagcaa cgacaacttc gaaaaggcct
    13741 gcaatttatg gatcacggca cgcgaaccgt gggaaaagag cgaagcttcc ttatcggccc
    13801 ggttgccaac ctaggtctgg accccaacat ggacagctgg cctttggacc agaacggtat
    13861 cgtacaggta ttgaattcac aaaactggga tgacctggaa tggagcggaa attttgacga
    13921 agaagatgaa gccatcggag ccgcacagag cgtacgtggt taccatacat tggaatatct
    13981 cctattcaaa gacgggcagc cccgcactgt cgatggagca aaataaacat gcctctgaga
    14041 cataaaactt gataatagat catgacaaac cttgaaacag cagacaaatg cccgctgttt
    14101 cagggtttca gagttattac acaatgcgac tcgcgttatt cggaaataaa ttcagaaaac
    14161 caataaaatg atatgaagca atcttacctg ttaacatcct cgctactcct gctctttgca
    14221 tgcgcagctt gtgaagagga cgataaaatg gatatggata aaatagatgt cccgaacgga
    14281 tatgcgctgt cagcagggac ttcaacgatt ttcctaaact catcggtcgc ctatgatacg
    14341 aacgccgact ggataacagg agccaactcg atccgtttca acaacggcga cggtctctac
    14401 gacgatgtac gcaccagcaa caacggagac ggaggcggtc tcggacctgt ttatgccggc
    14461 tattcctgcg gcagttgcca tcgaaatgca ggaaggacca aaccgacatt gtgggaaaac
    14521 ggcggatcgg gcaactacgg tttctcttcc atgctggtct atatctcccg ccgcaacggt
    14581 gctttcttcc gcgactacgg acgtgtattg cacgaccaag ccatctacgg cgtcaaaccg
    14641 gaaggtaagt tgtccgtcac atacgacaag cagacttttt ccttccccga cggagagact
    14701 tacgaactat gcaaacccaa ttacacgata accgaatggt ataaagacag tatcgccccg
    14761 gaagatttgt tctgcaccgt acgcatcccg ttacgccacg tcggtatggg acagatgatg
    14821 gcgatcgacc gcagggaaat cgaagcgctc gctgccaaaa gcaattatcc ggaatatggt
    14881 atcagcggac gttgcaacta tatcaccgag aagggtgtca ccggtgtcgg cctttcagga
    14941 aacaaggcac agcatcttga cctgaccgtc gaactgggct tttcaagcga tatgggcgtg
    15001 acaaacagcc gctatccgga agagatttgc gaagggcagg ctcagatcaa ccaaggcagc
    15061 atgatgggac tctcgtatga ccagctcgac atatcgaccg ccgatatgga agatgtggac
    15121 ctttatatgc aaagcctcgg tgtaccggca aggcgcaaca caaacgaccc tcaggtcatc
    15181 ttaggagaac aaaagtttta cgaagcgaaa tgccatctct gccacgtcac tacgctgcat
    15241 acgcaagcgg gtggttccac actgctcaac ggcacacgtt tgccatggct cggcggacag
    15301 accatacatc cttattctga tttcctactg catgacatgg ggtcggagat catgggggtc
    15361 gggttgaacg acaattatgt cagtggtctg gcacgaggaa acgaatggcg tactacgccg
    15421 ctttggggta tcgggctaca ggagaaagtc aacggtcata cctatttcct tcacgacgga
    15481 cgcgcccgca acctgaccga agccatcatg tggcatggag gcgaagggga agcctccaaa
    15541 aatttattca aacaaatgag caaggaagag cgtgaggcag tgatcgcatt cctcaactcc
    15601 ttataattta tccataagac aaactaaaat gaaacaactg ataatcacaa ttgcagcatt
    15661 attactattg ccgttgaccg tcacggccca atatgaggaa gatacggaaa acggtgtcgt
    15721 atcactaaac ggcaaagaag gttttacaat cgctaccaag aagggggatt tcgttttcaa
    15781 accttatatg ttggtccaga ccagtgctaa catcaactac tacgacgatg aagggctgga
    15841 cccggcctac aatcaggaca atatacacaa cagcggtttc tcgatcccct acgccatcct
    15901 cggtttcacg ggcaaggcat tcgaccgggt gacattcaac ctctccatca atgccgccgg
    15961 aagcggagga aacatcctcc aacaggcttg gttcgacgta gagatgaaaa agagttttgc
    16021 catacgtgtc ggcaagttca agactccgtt ctcgcac
//
