LOCUS       gnlProkkaKHECJKJN_68   13866 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KHECJKJN_68.
ACCESSION   gnlProkkaKHECJKJN_68
VERSION     gnlProkkaKHECJKJN_68
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 01:32:11
            Original ID  :: gnl|Prokka|KHECJKJN_68
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 119589
            Orig. end    :: 133455
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13866
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13866
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13866
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2153..3163
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_89"
                     /sec_met_domain="PF04055 (E-value: 1.4e-17, bitscore: 57.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
     CDS             3182..3796
                     /locus_tag="ctg43_90"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWLLPTQVLPTVTL"
     CDS             3796..4221
                     /locus_tag="ctg43_91"
                     /transl_table=11
                     /translation="MYSYPYTDKDTFTKEYFVHKRDSVMKANIPGFKEGVYMSTDSLLT
                     DVRPINVQNSYTMEARGLWRMKGDFMGGPYVSHTRLDEKNQRIITAEIFVYSPDKMKRN
                     LVRQMEASLYTLKLPNEVQQKQIPLGEASKEAEQTNK"
     CDS             4226..5320
                     /locus_tag="ctg43_92"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPIVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             5330..6571
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg43_93"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             6558..7085
                     /locus_tag="ctg43_94"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             7091..7864
                     /locus_tag="ctg43_95"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             7871..8266
                     /locus_tag="ctg43_96"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             8515..9903
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg43_97"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             10001..10351
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_98"
                     /sec_met_domain="PqqD_RRE (E-value: 2.4e-10, bitscore:
                     32.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.7e-17, bitscore: 54.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQYEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(10370..10561)
                     /locus_tag="ctg43_99"
                     /transl_table=11
                     /translation="MKHLNRANEPYPLPNTTPEEMERIIHDSEKKKEKDSNYFVWGTLI
                     IMGVLIAIAVILWAVFIK"
     CDS             complement(10558..10653)
                     /locus_tag="ctg43_100"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASAYVVNVLTIS"
     CDS             complement(10690..11757)
                     /locus_tag="ctg43_101"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(11831..13342)
                     /locus_tag="ctg43_102"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCHTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYST
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWQLVSE"
ORIGIN
        1 tacgctcatt tccagttgaa tggcttttca caggcggatg ccaagtcgtt ctcaaagcaa
       61 tatttgtcta cttactccaa ggctttgtct gcacagcagg aagatattct tgcttcgtgg
      121 gtgctggctg aacaaccgcg ctgtttaagt gtattgctca acgagctggt ttcgttcggt
      181 cagtacgatg ctctcaatga atatatgcgt ggatattgcc ggctcaatga ggttgggcaa
      241 ttctatgaca gtgtgctacg gcgtttgtcg gctgattatg gttccgaaga gattggaaga
      301 acgcttctga tgctttcact tactttagaa ggatttaccg aagatgaagt gaagagcatg
      361 gcagacatta atcagatact ttggtcgcag ttgagagtgg aaatgagcag ctggctcacc
      421 aacaaaggag gacgatattg cattggtgat acacaaatgg tagaggcgat cgaacgctat
      481 ttcgctcaag atgacgaatg tatagatgat agtcgccatg aaattatttc cgctctgctg
      541 gatgaggaag agatcctttc ccatccgttg acttttgccg attataacta tcgcatgaaa
      601 cagttctgct accatgattc gtatcgctat aaagtggaga ttacctatca atgctataag
      661 atgcaagaat gggatatatt gaaggattgg atttgtgatg tggagatttt cgagattctg
      721 tatcgcacga atcgttctct gttggaagat agctggaagg cgatcatgaa cgacaatcct
      781 gaagttacgc ctgaagtcta tgctgaattg gactttgatg agatcgattc ttttttaatt
      841 cctgtcattg ctaatgatat ggctactttc ttgagcagtt ctttccatct gacgaaggcg
      901 gcagctgctg tgagtgagaa gagtatggaa ggtgctgcca tgccactcat tgccaagtcg
      961 gtattgaaga tgaatgaggg atgccggtat gcccgtaatg aagagtacga aacggcatgc
     1021 gactgtttcc tgaaagcatt ggtgatgcag gaaaacatag taccgactcc ggaactggag
     1081 attgccaaca cctgccgaaa tctagctctg gcatattact acaatgagca atacaatgaa
     1141 gcagtgacct atttgaatag ggcgcttgat tatcatgcgg cttctgctga tgagaagagt
     1201 caggcagaag tcattgaact ttccgaatat ctggcttatt gtgattacta taaggatgag
     1261 gaagagaggg ctgccgagaa attccggaaa gtagctgaaa tgcacgagtc gttgaatggc
     1321 agactgtctg gtggagtggc taaatgtttg cgtatgcagg gtaaatgtct ttattatatc
     1381 aaacgatacg atgaagcatg gatgctgatg aatcaggcgt tggacattgc tatacagata
     1441 gacagcaaaa gacagatcgt cgcttgtcat aaacagttgt attatctatg cagggaattc
     1501 aaacggatga tgaatgaacg tggcgatgag caggcgtcta ctttattctt ccgtgagtct
     1561 cttctgcatg aaatgtattt cagcgaaaaa ccgcgtctgg cggaactgac tgtccgctac
     1621 gaggcattga gatgtgatat tatgcagcag tattacatga ataaagacta tgataacgtg
     1681 attcgtattg caacgtcttt ggattttcac gatgatgctg accctaatgc ttcctgtctg
     1741 gtatattatt acaaagcaca ggcttatgtg aagttggaga attatccaat ggcgaaagag
     1801 gctttcttca gagagcttga actgcgaaag aaatatctgg gatgggagga agaagatacg
     1861 attctggctt gtcagaactt aggggttttg cacagctttt gtaatgaacg ggaagaggcg
     1921 ctggcttgtt tccgtgaggc gtacggttat gaagtgaaaa agaatggcga ggattctgaa
     1981 atggcgcaaa agctacttca atatatcagc gtggttgaat cataacggag gcatacttcc
     2041 cttttttgtt aacttttaca ttcctgctat acggaaatcg actttatttc cttacatttg
     2101 cagatataaa ctatcaacag aaagaagaat gtctaaatat ccccttttag gaatgactct
     2161 tgtagagctt caatcattga caaaaagact gggtatgccc ggctttgctg ccaagcagat
     2221 tgcatcctgg ctttacgaaa agaaggtagc ctcgattgat gatatgacta atttgtcatt
     2281 gaaacaccgg gagttgctca agcagaacta tgaggtggga gcggaagctc cggtagatga
     2341 aatgcgctct gtagatggta cggtgaagta tctttataaa gtgggtgaga accattttgt
     2401 agagtcggtt tatataccgg atgatgaccg ggcaacgttg tgcgtgtcgt cacaagtggg
     2461 ctgcaaaatg aactgtaagt tctgtatgac cggcaaacag gggtatacag ctaacctgac
     2521 cgccagccag atcataaacc agattcattc gctgccggaa cgggacaaac tgactaatgt
     2581 cgtaatgatg ggaatgggcg agccgctcga taacctggat gaggtattga aggcattgga
     2641 actactgacc gctacctacg gttacgcatg gagtccgaag cgtatcacgc tttctactgt
     2701 cgggctacgg aaaggattgc agcgttttat cgaagaaaat gactgccacc ttgccatcag
     2761 ccttcactct ccgctgaccg ttcagcgtgc tgaattaatg ccggcggaaa aggcgttttc
     2821 aatcaccgaa atggtggaac tgttaaaaaa ctatgatttt agtaaacaac gtcgactttc
     2881 gtttgaatat attgttttta aagggctcaa tgattcgcag gtctatgcca aagagttgct
     2941 gaaacttctt cgcgggctgg attgcagggt gaatctgatt cgttttcatg ccataccggg
     3001 ggtagacctc gagggagcgg acatggatac gatgacccgt tttcgtgatt atctgacgtc
     3061 acacggactt ttcaccacta tccgttcatc caggggcgaa gatatttttg ccgcttgcgg
     3121 tatgctgtcg acagcgaaac aggagaaaaa taatgaaagt taatatataa aaccgaacat
     3181 catgaaaaag tactctttta ttttatgcat cgctttggta gcctttgtcg ttgcatcttg
     3241 tggtctgaaa ggaaatcaca cctctagtgg tcgtgcttac gagcttttgg ttgtagtaga
     3301 tcacggtgtt tgggatcgtg ctgccggaag ggctttacat gatgcgctcg atgctgatat
     3361 gcccggtttg ccgcagtcgg aaccttcttt ccggattatg tatacttcgc cgaaagatta
     3421 tgattctacg ctgaagttga tacgtaacat tattattgta gatatacagg atatatatac
     3481 gaaagcctcg ttcaaatatg cgaaggacgt gtatgccaat ccgcagatga tattgactat
     3541 ccaggctccg aacgaagaag agttcgagaa gtttgtggaa gagaacaaaa agacgattgt
     3601 cgacttcttt acccgtgcgg agatgaaccg tcagattacg ttcctggaag ggaaacacag
     3661 taatttcatt tcgcagaaag tggacagttt gttcggatgc gacatctggg tggatgccga
     3721 actggctaat tcaaagaccg gggatgattt cttctggctt ctaccaacac aggtactgcc
     3781 gaccgtaact ttgtgatgta ctcttatccg tacactgaca aggatacgtt taccaaagaa
     3841 tattttgtgc acaaacgtga ctccgtgatg aaagccaata tccccggatt caaggagggc
     3901 gtttatatgt cgaccgatag tttgctgacc gatgtccgtc cgatcaatgt acagaacagc
     3961 tacacaatgg aagcacgtgg cctgtggcgt atgaagggcg actttatggg tggtccgtat
     4021 gtatctcata ctcgtctgga cgagaaaaac caacgaatta ttacagcaga aatatttgtt
     4081 tattcacctg ataaaatgaa acgcaacctg gtacgccaga tggaagcatc tctgtataca
     4141 ctgaaacttc cgaatgaagt tcagcagaag cagattccat tgggagaagc atctaaggaa
     4201 gcggaacaaa ctaataaata aaaacatgga agataacaag ataaggatag gtatcaccca
     4261 aggagatatt aacggggtgg gctatgaggt gattcttaag acattttccg accctacgat
     4321 gttggaacta tgtactccga tcatttatgg ctcaccgaaa gtagcggctt atcatcgcaa
     4381 agcgctggat atacaggcca atttcagcat tgtcaactct gctaccgaag cggggtacaa
     4441 ccgtttgagc gtggtgaact gtacggatga tgaggtgaaa gtggaatttt ccaaacccga
     4501 ccccgaagcc ggtaaagctg cgctgggggc tttggaacgt gccatcgaag aatatcgcga
     4561 agggttgata gacgttatcg taacagctcc gatcaacaaa catacgattc agtcggaaga
     4621 gttctccttc cccggacata cggaatatat cgaagaacgt ctgggtaatg gtgataagtc
     4681 attgatgatt ttgatgaaga atgacttccg ggtggctttg gtgacgacac atatccctgt
     4741 cagagagatc gcgactacga ttaccaaaga actgattcag gagaaactga tgatattcca
     4801 tcgttgtctg aaacaggatt tcggtatcgg cgctccgcgt attgcggtgc tctctctcaa
     4861 tcctcatgcc ggagacggtg gtttgttggg aatggaagag caggaagtga ttatccctgc
     4921 catgaaagaa atggaagaga aaggaatcct ttgctacggt ccttatgcgg ccgacggctt
     4981 tatgggttcg ggcaattata ctcattttga cggtattctg gcgatgtatc acgatcaagg
     5041 gctggctccg tttaaggcct tggctatgga agacggggtg aactatacgg caggcctgcc
     5101 gatagtacgt acttctccgg ctcatggaac ggcatacgat attgcaggca agggagtggc
     5161 ttgtgaagat tctttccgtc aggcaatcta tgttgccatc gacgtgttcc gtaatcgtca
     5221 gcgggaaaaa gtggctcgtg ccaatccgtt gcgtaaacag tattacgaga aacgtgacga
     5281 tagtgataaa ctgaagctgg atacagtaga cgaagattaa aaacgagtga tgacgaaagc
     5341 agagatacaa caagtgaaac agcgtttcgg tattattgga aatactgaag cattgtcgcg
     5401 cgccatagat gttgccattc aggtagctcc taccgatttg tctgtgctga ttaccggaga
     5461 aagtggagtc ggaaaagaaa gttttccgca gattattcat caatatagcc ggaggaagca
     5521 cggacagtat attgctgtca actgtggcgc tattccggaa ggtacgattg attccgaact
     5581 gttcggacat gagaaaggtg cgtttaccgg tgcgattggc gaacggaaag ggtactttgg
     5641 cgaagctgac ggtggtacta tttttcttga tgaagtaggg gagttgccga tgtctaccca
     5701 ggcacgtttg ctccgtgtac tggagagtgg cgagtttatg aaagtaggtt cgtccaaagt
     5761 acaaaaaacg gatgtgcgtg tggtggcggc taccaacgtc aatcttacac aagcgattgc
     5821 agaaggacgt ttccgtgaag atttatatta ccggttgaat acggtgccta tccagatacc
     5881 gcctttgcgt gaacgtggtg acgatgtact tttgttgttt cgtaagtttt ccgcagactt
     5941 tgcagagaaa taccggatgc ccgctattca gttgacggag gatgcgaaga aagagttgtt
     6001 ggcttacccg tggcccggaa acgtgcgtca gttgaagaac atcaccgagc aaatatctat
     6061 cattgaaacc aatagggaga tctctgctgc tatcttgcag aattatcttc ctgcacaaaa
     6121 tacgcaacgt cttcccgcgt tgatgggaac gcgtgagagt aaaggctttg agagcgaacg
     6181 ggagattctt tattctgttc tgttcgatat gcgccaggaa gtggcggagc tgaagaagat
     6241 ggtgcacaac ctgatggcgg aacgtgccgg acaggtgggg caggtaggac aaatgggaac
     6301 ggtggttact actccggtag tgacggcgca tcaaccttcg gtacctgcta tcattcacac
     6361 catgcagcct acggtttgca aggatgatga tgacatacaa gacacggaag aatatgtaga
     6421 agaatcccct ttgtcactgg acgaagtgga gaaagaaatg atacgcaagg cacttgagag
     6481 gcatcatgga aagcggaaga gtgcggccaa ggacttgaat atttccgagc gtacacttta
     6541 tagaaaaata aaagaatatg aattggatta agaaaataat acgccctttg ttactgttcg
     6601 gcttgccgtt ggtagtcatt gcgtgcactg tttcctataa gtttaacgga tcgtctatca
     6661 attatgataa ggtaaagacc atttcgatag ccgacttccc gatcaagtcg gagtatgtat
     6721 atgctccgtt agcaaccaaa ttcaatgagg acctgaaaga tatcttcatc cggcagaccc
     6781 gtctgcaact gctcaagccg aatcagaatg cggacttgca gattgacgga gaaatcacag
     6841 gatacaatca gtacaaccag gcagtatctg ccgacggtta ctcttcggag acgaagttga
     6901 ctattaccgt caatgtacgt tttgtcaaca acaccaatca tgccgaagac tttgaacaac
     6961 agttttctgc gttccgtacc tacgactcta gccagttgct gactgccgta caggacggat
     7021 tgattgctga aatgtctaaa gagatcaccg accaaatttt taatgcaact gtagcaaact
     7081 ggtaatataa atgacttctg ttaactttca acaatggatt cagcatcccg agacgctgaa
     7141 tagggatact ttgtacgaac tgcgcaatct tcttgcgagg tatccgtatt ttcagtcact
     7201 tcgtctgctg tatctgaaga atctgtatat tctccatgat attagtttcg gtggagaact
     7261 gcggaaagca gttctttaca ttgcagacag acggcagttg ttccggttga ttgaaggtga
     7321 ccgctatgat gtgcaggcac ggaaaaaggg agtacctctc acggaggtgc tgaaagacga
     7381 accgtccgta gaccgcacat tagcattgat cgacgctttc ttgtctacag tacccgaaga
     7441 ggtgactgcc cgcaccagct tcgactattc gatggattac acctcttatc ttttggagga
     7501 gactccggcc acggaacagt cggccgaaga aacgcccaaa ctcaaaggct acgaactgat
     7561 tgacgacttt atagaaaaga gcgagagcga ctctcccctc tgcaagaaac ctttaagaga
     7621 agaaatgcca tcttcgccaa cctcttcgga cgaacttacc gaagaagaaa caatgaagga
     7681 agaagaggaa gatgacagct gttttacgga aactttggca aaaatctatg ttaaacagca
     7741 acgatattca aaagctcttg aaataattaa aaaattaagc ttgaaatatc caaaaaaaaa
     7801 tgcttacttt gcagaccaaa tcagattttt ggagaaattg attattaacg ctaattcaaa
     7861 ataactaaaa atgtacttat tattcgttat cttaatggtt attgcagcct tgttgatgtg
     7921 tttcatcgtg ctgattcaga actcaaaagg aggcggactt gcttctggtt tctcttcatc
     7981 taacgccatc atgggcgtgc gcaagactac agattttctg gaaaaagcaa catggggctt
     8041 agctatcttc atggtggtaa tgagcattgc tactgcttat gtagttcctc gctctgctgt
     8101 tgctaaagac gcagtgttgg aacaggcaca gaaagaacaa cagactaacc cgtataactt
     8161 acccgcaggt acggctgcgc cgcaaactga agctcctgct accaatgcac ctgctacaga
     8221 aactccggca ccggctactg aaactcctgc tcctgcagca gagtaattca ctccgttgtc
     8281 aggtaagact ttggggtaaa accattaatg ggaaggtgca gacggatgct gcatttcttt
     8341 gatatttaag tgcggattac gcagattaca cggattttca atcttccgcg tggtcagtgt
     8401 aatccgcact taactttttc ttgtaaaaac aatctctttt tgatagaaac aaacgagatt
     8461 taactacctt tgttggtcgt atgaagatta ttaactactt ttttaaatat aacaatgaca
     8521 gaacatttga aacagaaatt gaatgactcc gccgtactcc gatggagtgt tctagcattg
     8581 gtcgcattta ctatgctatg cggctatttc ctcaccgacg taatgtctcc tctaaaaccc
     8641 atgcttgaga aagaactact atgggacagt cttgattatg gtttcttcac aagcgcttac
     8701 gggtggttta atgtattcct gttgatgctg attttcggtg gtatcatttt ggataagatg
     8761 ggagttcgtt tcaccggaat gggggcttgc ttattgatgg tgtttggttg tggattgaaa
     8821 tactatgcga tttctactac ttttccggaa ggtgccatgc tctttggatt caaaacacag
     8881 gtaaccctgg ccgcattggg gtatgctatc ttcggtgtag gtgtggaaat tgccggtatc
     8941 acagtttcca aaattatcgt aaaatggttc aagggtaagg aaatggcatt ggctatggga
     9001 cttgaaatgg ctacggcacg tatcggaaca actctggcaa tggtgctcac ggttcctttg
     9061 gccgacttct tcggatctac ggatgagagt ggcacattcc ataccaatat tcctgctccg
     9121 attttgtttt gtctgattat gttgtgcgtg ggtacgattg ctttcttcct ttatactttc
     9181 tatgataaga agttggatgc ttctttggat gcagagggat tggaaccgga agaaccgttc
     9241 cgtatgaaag atattgtgta tatcattacg aataagggat tctggttgat tgcattacta
     9301 tgtgtattgt tctactcggc tgtattcccc tttatcaagt atgctgccga cttgatggtg
     9361 cagaagtata atgtagatcc gaagttggcg ggaacgattc ccggattgtt gccgattggt
     9421 gcgattatcc tgactccgtt gttcggctcg ctttatgacc gtatcggtaa gggagctacg
     9481 ttgatgataa tcggatcagt gatgcttatt tttgtgcata cgatgttcgc tctgcctata
     9541 ctgaatatat ggtggtttgc tactatcatc atgattatat tgggatttgc cttctcgttg
     9601 gtgccttcag ctatgtggcc gtctgttccg aagattattc cggaaaaaca gttgggtacc
     9661 gcatacgcat tgattttctg ggtacagaac tggggattga tgggtgttcc tttgttgatc
     9721 ggatgggtgt tgaatactta ttgcaaaggt ccggtagtag acggtgcaca gacttatgac
     9781 tacacgttgc cgatggctat ttttgctctc tttggtgtgc ttgctctgat tgtggctttg
     9841 atgttaaagg cagagaacaa gaagaaggga tacggtctgg aagaggcgaa tatccaaaag
     9901 taactgggaa attcaatacc taaagtgaca aaggaatttt gtatcaaggt gtaaacagaa
     9961 gagtatcagt atgaatactc tgaaataaaa aataagaagt atggctgcca aagagaaaat
    10021 caacctgtta gaggtcattc cctgtcgcag tgaacatatt acagcagaaa gggaagggga
    10081 gacaattgtg ctctcctttc cccgttttaa atatccgtgg atgcaacgct tccttgtgcc
    10141 gaaaggaatg tcgaaagaac ttcatgtgaa attggaagaa cacggtacgg ctgtatggga
    10201 actgatagat ggaaaacgca atgttcgtga gattatagaa aaactcgcag accactttca
    10261 atatgaagag ggctacgagt cgcgtgtatc ggcttatctt tctcaaatgc agaaagatgg
    10321 atttataaaa ctggtgatac cagtcgtata aataggaact tattattatt tatttgataa
    10381 atacagccca aagtatgacg gcaattgcta tcaggacccc catgataata agcgttcccc
    10441 aaacaaaata attgctgtct ttctctttct ttttctccga gtcgtggatg atacgttcca
    10501 tttcttcggg ggtggtgttg ggtagtggat aaggttcgtt tgcacggttt agatgcttca
    10561 acttatcgtt agcacgttca cgacgtaggc ggaagcttcc cgtccctctt ttattcggcg
    10621 tatcatgtcg aatgcatgtc cttcaccaac catattcttt gttttttaga agtttacttc
    10681 ctcgtttttc tatttccctt cttctctgtc cactttgagc aatcctcccg tattcggatc
    10741 aaaataaact ttgatggtag aattcttgtt gaacaaaacc ggagccagat attctatcac
    10801 accaaattga gtaataggaa gctcaccttc gtaaagtttc tttttaccgt cggtcagtgt
    10861 aaccatagct tgtccgggga cgttgtaggc gattccatcc aaatctttct tcttcttacc
    10921 atcttcctgt ggcatcttga ccgatttcag gtctttcaga ctgatataaa acggagttcc
    10981 tgccaaatca ttgttggcaa ctacacctaa cttcttcgag aagcggaaag caacttcatt
    11041 gttgaattcc ttgtcagggg taaggcggac agtgaatgtt ctctcttctt tgttgcaggt
    11101 gccggagaac atttgcgtca tggcttcttc ctgtgcattc agattgtcga gcataatttt
    11161 aagctgtgct ccgtctgaag gcatattgtc agcctgtccg cgcaataagg catttttgct
    11221 ttcgcggatg ttatagatct ctttagccac cagctcggcc atcttggcgg tagagctggc
    11281 catcagaatc tcctcggtca ggaattcacg aggattcgct ttcttttgga ggactgcggg
    11341 ggcgggagca gcttttttgc ctacactgct attgctgtaa ggaacattga tcgttttcac
    11401 aatgccatcc tctgtcagtt ccatgagcgg tgctactgtc ttatccttca attttacgaa
    11461 atacgtagtt tcgctgttgg gcacacctac ggatttcact tttacgctag ccagttccca
    11521 gtactcttca gggtcggcgg agacgttggt cagtcgcagg taacgatcag catatttgct
    11581 gaattctccc ggagtatagt tgactttgtt ggcttttatt tcaagttcta tttgggtttt
    11641 gggaagactg taaaccactc catagtcttt tcctcgggta acccctgtca gtacttcggt
    11701 ttgtgcatag gcggacgttg tcattagtag tcctgctgct ataatcaact ttttcatatt
    11761 cggttctttt ttaactggtt ttgaaaacaa agttaatgaa gttattgaaa aaagggtaag
    11821 ttcttaactt ttattcgctt acaagttgcc atgctgtcgg cagacaggtg ataatatcgc
    11881 ttgcgatcat tccgatcatt ccttgcttct tttgagcgac atcgcccgcc aatccgtgaa
    11941 tgtaagtgcc gattttagcg gcttcttcgg ttgagtaacc ttgggcaagc agtgccagga
    12001 ttactccggt cagtacgtca ccgctacctc cggttgccat tcccggattt ccggttgggt
    12061 tgaagaaaca tttaccttct ggggtgataa tggcggagta ggctcctttt aaaataatgt
    12121 gaacatgggc ggcacgagcc aattcgcaag ccttcatcag acgttcgtaa gagtcctggc
    12181 atttgccggt cagacgttcc agttctttcg gatgcggggt gaggatggaa cccttcggca
    12241 ggtgggtaag tgcatgacgg tggttggcga ggatattaag tgcgtcggca tccaccacaa
    12301 caggagtatg gcaatgttcc agttgctcca ataaagcagc ttccgtttcc tcgtttcgtc
    12361 ccagccctgg gccgatgccg actgcttgat agtcgtccgt gtcggtaggt acggcaaaac
    12421 aggtttcgtt gatgtcggtt tctacgattg cttcgggtat ggaggtctgc aagatgtcgt
    12481 tgttgcacat tggcgcatgg acagtcagca accctactcc cgaacggagg caggcgcggg
    12541 cagcgagaac agaggctcct gccattcctt ttgaaccggc aatcaatagt gcatggccga
    12601 agttcccctt gtgggcaaac tgtttgcgtg gcttgatgag tgaacggatt tgctctattt
    12661 ccaacatttc gtagttcgtt tccatctctt caataccgtc ttcgcttaat tggatgtcca
    12721 gcacttccca ttctccgaca aattccgtgt tctctgcgaa aagaaaggcg agcttcggca
    12781 gttgcagact gaaagttacg tcggcacgga taatattagc ttttacgttg aatgtgtttt
    12841 cttctcccat cagtccggaa ggaatgtcga tggctactac catagcaggg gaggaattga
    12901 tgtatttcac tacggcagcg aatccgccgc ttaacggttt gttcaggcct gaaccgaata
    12961 atccgtcgat taccagatgg tcgggcgtca ggacgggagg tacgaattgg gtactgattt
    13021 cgtggaattt tacttcttcc atcatttcta ccagttcttt attggtttgg cagtcgggtg
    13081 aaagttctcc tttcgtgttg aagagaaata cctcgatttt atatcctttt tcagccatca
    13141 tgcgggctac ggcgagagcg tctccgccat tattccccgg tccggcaaag atagtgaccg
    13201 gcgtttccgt attccatctg tctgtgatgg cttttgttaa tacggttgct gcacgttcca
    13261 tcagatcgat tgatgcaata ggttcgttct caatggtata agcgtccaat ttcttgatac
    13321 tgctgcttgg aaatattttc attgcgatgt tcttttagtt ttcggattac aaatgtacat
    13381 gattcttctg acttttcccg tttgttgtgg gaagaaaacc ataattgcaa cttttaattc
    13441 atcattagtt ctatctttgg gtcagagaaa tatctgcttt tgaactatta agtgttagaa
    13501 taactccgcc aaaaaataat tcaatgcagc accattatga acttactttt atttctcctg
    13561 aaaaagattt ggttcttaat caaattccgt gctagtaaag ctcattgaaa ggccgatgga
    13621 taaagggata tcggcatatt agaaatagca aataaattat ccaaactata tgcatcttaa
    13681 agtactccgg aatagccatg aataaggtaa ttgaacataa ataagtagca cggaatttga
    13741 agaagaacca aagatttcgg ttcttcgtca aatttggtgg taatctcttt tttatttcaa
    13801 ctgtcttctt ctttcttaat cctattaaaa gttgtagata tgtttgcttt ttagtaactt
    13861 taaaga
//
