LOCUS       c00024_gnlPro..        15568 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KHECJKJN_24.
ACCESSION   c00024_gnlPro..
VERSION     c00024_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 19:09:36
            Original ID  :: gnl|Prokka|KHECJKJN_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 140115
            Orig. end    :: 155683
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15568
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[150115:153628]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13513
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15568
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15568
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(1615..2616)
                     /locus_tag="ctg24_115"
                     /transl_table=11
                     /translation="MDGDYTEPVLTPSIGLLSDNINIVLSEGTSKTFRFTAEDNKELDY
                     LELAVPDLEILERQDIEEGEKKGTLNTTVVFPSDKTGTYTLVIRAVDTFGNVAEKNYSV
                     LVSRVKDYENMYLVDFEGTDSKLLTGNDVWGVPMPIERVTNFTYKARCYSPAPNTPIRF
                     ITSKYSFSICFGDDKNNPGKLTGISEDVQPIILPEKSYYEINFNTEEGTYTVEAYSPGT
                     PIIDGLKMGFVGGWFDGAKGWDGPKNVYELTQDPDNPHCLTAELTWSKQDSFDVTITPY
                     NANGDWLEPGWRFDGKNESFATNTNDSSKKVPAGKYTFIFDTHLVQSKLLKK"
     CDS             complement(2667..3017)
                     /locus_tag="ctg24_116"
                     /transl_table=11
                     /translation="MKAKLLQSTVLWTFLSAATLFVGCSDDEDYRDVDGQSPTLELTSD
                     HIRTLTGYEFKIAGKIADKDGIRSINLQCAELYLDKTIELSALYSEPLYEYNLNYGFTI
                     PEKTKGDSFTIK"
     CDS             3237..4355
                     /locus_tag="ctg24_117"
                     /transl_table=11
                     /translation="MKKHIASILFLCLLSVSQSIAQSHSIKRLGIEQGLSNNYVISIAQ
                     DKQGFLWFATEEGLNKFDGTRFITYYKNDLSQSSQGITGNELNRVYADNKRPIIWIATQ
                     RDGLNAYNYNKQAFTAYSHNPDDPHSLITNDVTDIAPSAQHEDGLWISTYYRGIEYLDI
                     NSGQFTHYNKNTVPALSCEQTWTVLDGGDGNLYIGHVGHGFSILSLKDKNVKNFQNHSG
                     DPKSLPGNDVRCLTKDTNGNIWLGTDKGLALFNVADQSFITFKNNKNDRYAALCNRILA
                     IKQLNDGKLWIASELNGITILDLKQSMFLSPEQVSLEYIQEGDDSRSLSNASARCIFQD
                     SFDNIWIAHGRRNQFYQQKATLIHNIKLFSDS"
     CDS             4384..5940
                     /locus_tag="ctg24_118"
                     /transl_table=11
                     /translation="VSSLCTDRQRRIWIGTDGGGINVFEGDKRIAIYRKETGDIPSNFI
                     LTALQDSKGNLWFGSFQGGISYYDTRNKRFRSISLMGQYNQDVRTIYEDTQHNIWVGYS
                     GGIIVLNPLNMEIIRHYNTENSELHSDFVRSIAQDEKGRFWIGTFGDGLGVYTPDLQKI
                     KTFVQRDGFCSNTVNQIIQDKHKRMWIGTGEGLVCFPSTDALTYKTYQRKDGLTNTNIC
                     AITEDKKGNIWFSNNKGVSCYVTSKDCFYNYGHSDDVPAGSFSSGCVTQNNNGWIYFGS
                     INGVCCFNPDIAMNEQPTPSAVITEMKILGRLSNLENNDMIINLSKGQNVELSHAQNSF
                     GLTFNVQNYSLVNQVEYVYMLKGLENSWYTVNENNSVTFRNIPPGKYEFLIKARVHNQE
                     WPEEATSLTIRVNPPLWLTWWAKLIYIWVSISIIYLILHAYKKKLDLESLYTLEKKNHE
                     QEQELNQERLRFYTNITHELRTPLTLILGPLEDMQKETSLPAKQARSYLSSIRVHYGCS
                     T"
     CDS             5937..7352
                     /locus_tag="ctg24_119"
                     /transl_table=11
                     /translation="LINQILEFRKTETQNKKLCVSKGNIAPLIYEIGLKYKELNQKTKI
                     DFQIQIEKEEMLLFFDKEIITIVLDNLISNAIKYTEQGRVTLSLYQTMRNEVAYTEIKV
                     SDTGYGISAEALPHIFDRYYQESGKHQASGTGIGLALVKNLVTLHEGEIRAESIQNEGS
                     TFYISLLTDNIYPNALHADSTEPIQEDTNQEASLEYPQETTLDIGKPILLIVEDNEEIQ
                     KYIAESFADSFEVLTAYNGEEGKQQALSRIPDIVVSDIMMPVMDGIILCRQLKEDVRTS
                     HIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINNLLESRKKLIAQFQTQS
                     VPGNQADLKEKRIVIAEALSKLDNEFIEKITLLIEENLSSEKIDITYLSDKMCMSGSTL
                     YRKMKALTGLSTNEYIRKVKMQNAERLLLEGKFNISEIAYKVGMNSTGYFRQCFKEEFG
                     VSPSDYLKQIIQS"
     CDS             complement(7682..8641)
                     /locus_tag="ctg24_120"
                     /transl_table=11
                     /translation="MLRKIVFFFFFLFVGLSLFAQQDYMVSSYVRGNFYNRGRISTESL
                     RASDDLIFLNVHPNKDGSLSFENPRAFQGKGVTTWEGLIKSVRAKVKGTKVKIRLGASS
                     GEWKAMVADEAARTTFAKNIKTVLEKNKLDGIDLDFEWAENEKEYKDYSLAILKMREVL
                     GNKYLFSVSLHPVCYKISKEAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVLEYGIPK
                     EKLVAGVPFYGVTKDNSKKTEAYFNFVQNGLVTSPAQNEVIYQGDTYVFDGQDNIRIKT
                     RYAKEQKLKGMMSWDLATDLPLSDSRSLLKTMTEELRE"
     CDS             8920..9789
                     /locus_tag="ctg24_121"
                     /transl_table=11
                     /translation="MPRDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVIYWFNELPLLCEDR
                     YKEMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLGSFFYPISTYTESFHYFVMQNYSKVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             10001..10705
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_122"
                     /sec_met_domain="SucD_FumR (E-value: 4e-131, bitscore:
                     427.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             10743..12617
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.8; E-value:
                     3.2e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_123"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.6e-62, bitscore:
                     202.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.5e-20,
                     bitscore: 64.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEINGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESVVVTSVKNTRLKKEKLNVMTKTSSM"
     CDS             12758..13513
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_124"
                     /sec_met_domain="Fer4_7 (E-value: 9.3e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 6.7e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.1e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             13830..14234
                     /locus_tag="ctg24_125"
                     /transl_table=11
                     /translation="MDLAENRFGKTWKHFLEALKVDYNCSLADVCRDQHTTFGGMSSWM
                     SRRGYSVKQAKADVVRDYYGGVEPSQPTTSSPSFTQISPAMLSEEEFSLAGITITFNSG
                     TTISVKRATPGGVIKMLRDYERTEGDPCIL"
     CDS             14321..14572
                     /locus_tag="ctg24_126"
                     /transl_table=11
                     /translation="MKDLSPVSGDIFLFFGKNRQSVKILRWDGDGFLLYYKRLEGGSFE
                     LPTFNPNTGNYEISYQVLSFILNGVSLKSVRLRKRFRI"
     CDS             14659..15567
                     /locus_tag="ctg24_127"
                     /transl_table=11
                     /translation="MKKDEIIELLKEQIKGLRDDNNRLLDQIDALIKEVSSLKEALLQK
                     GESLSKQQRLTKGLAKLVSNTSEQQQAPQSAISEEERQKIEAEKADKRKARKNNGAKRD
                     MHYEMEEEEHVVYPDDPDFDINKARLFTTVPRICVRYECVPMRFIKHVYKIHTYTQEGR
                     LFEGKTPASAFLNSSYDGSFIAGLMELRYIQSLPVERIINYFESHGFTLKKPTAHKLIE
                     KASDLFENLYKCIRQTALSDPYKAADETYYKILVPEKNSKGKGVRKGYLWVVVGINTRM
                     IYLLYDDGSRSERVILNELGSC"
ORIGIN
        1 ataatgcagg ttctcttcat tggtaggagt gcgttccttt gatccttcca accaatattc
       61 ctggaaacgt tccatcgtat aaccagccat cacattcaaa ttgtgtttat gattaaaact
      121 cttaatccag tttactgtat tcgtccagtt ccagtccacc caattatcgg ttttacgata
      181 tgctttgctg taatcggatt tctctaatgt atcgatattg aaagaaggag taaactcatc
      241 tgaaatacgg aaacgggcat tgacaccaaa ctgtgaacga ataaccaagc ctttaatcgg
      301 ttcaatgttt acatacggat tggctaataa accatactca tcactatgtt tatccatacg
      361 ggctaattgg gcaaccggat tccacaccaa gttgttgctg gaacgggcat agttgtcgta
      421 ttcattagtc gtccattcac tttgaggacg catgatcgga gttgtggggt ccatagccat
      481 tatatttccc aataaactgg gagtatctgt ccaattctca tatttcgggg taaagtcaat
      541 acctgctttt actatattat taaaagtgta ttccatactg aaacgggctg tcagcttttg
      601 ccagttacct acagtgtatt gtgagtcttg cccgaaataa ccaatattgg cagagtaaag
      661 caacttatcc gtacctccgg agaaattaaa attataatta tgaatcagtg ctgtcttctt
      721 catgctttca tcccaccagt cagtaccttc cgcatctgtg atattctcct tgctgttata
      781 acggggctct gcattatcat taatataacg cgccttgaac acatattcgt attcggaagc
      841 ttttgccatc tccggtttct tcaatgtctg aaaaccggca gaagcagaga aaccgaattg
      901 ggtagctccc tttttacctt tcttggtagt aataaggaca acaccgttag agccacgtgt
      961 accataaata gctgctgctg aagcatcttt cagcacttgc atggattcaa tatcgttctg
     1021 gtcaagaaaa ttgatattgg ttcccaccgg cattccatca acgacataca acggatcaga
     1081 accattgacg gtagataccc cccgaataat aacacgaggt gaagtacccg gaccgccacc
     1141 accggtaatc tgcacaccat taatctttcc ctgcaaggca ttcatggcat taccgccagt
     1201 cagctttttc agttcatctc ctttgatagc agatatagag cttgtcaagt cactcttctt
     1261 cactgcacca tagccgataa caactacttc atccaaagct tgtgtatcat cttccatgac
     1321 tacatttatg acattctttc cattgacttt aacttcttgt gtcttatacc caatcatgga
     1381 aaatacaata gtcgcatctt taggaacatt agtcagtgta tagtttccat ccagatccgt
     1441 gacagtacca tttgtagtac ccttcaccag aacagtcaaa ccaatcattg gttctttatc
     1501 actagctgca atagcagtac cagtcagact tccctgctga gcataaaggc tcagcgcaaa
     1561 gaacgataat aataaaaata gatatcgttt catgttttta tggcattatt ttaattattt
     1621 cttcagcaat ttagactgaa caagatgtgt atcaaatata aaggtgtatt tacctgcggg
     1681 taccttttta gatgaatcat tcgtattagt agcaaatgat tcgtttttac cgtcaaaacg
     1741 ccaacctggc tccagccaat cgccattggc attataggga gttattgtca cgtcaaaaga
     1801 atcttgttta ctccaagtca attctgcagt gagacaatgc ggattgtccg gatcttgagt
     1861 caattcatag acattcttag gtccgtccca gcctttggcg ccatcaaacc atccgccaac
     1921 gaatcccatt ttaagtccgt caataattgg tgttcccggc gaataagcct ctactgtata
     1981 ggttccctct tctgtattaa agtttatttc ataataactc ttttcgggta gaatgatcgg
     2041 ctgtacatct tcagagatac cagttaattt tcccggatta tttttatcat caccaaaaca
     2101 gatgctgaag ctatatttgc ttgtaatgaa acggatcggg gtatttggag caggtgaata
     2161 acaacgagcc ttataggtga aattcgttac tcgttctata ggcatcggaa ctccccacac
     2221 gtcattgcct gtaagtaatt tactgtctgt tccttcaaaa tcaaccaaat acatattttc
     2281 ataatctttc actctggaaa caagtactga atagttcttt tccgcaacat taccgaaagt
     2341 atcgacagcg cgtataacca atgtataggt cccagtctta tcagaaggaa atacaacagt
     2401 agtattcaat gttcctttct tctctccttc ttcaatatcc tgacgttcca agatttccaa
     2461 atcaggaaca gctaattcca aataatccaa ttccttatta tcttctgcag tgaaccggaa
     2521 tgttttagaa gtaccttcgg acaacacaat attaatatta tcacttaaaa gaccaataga
     2581 cggagtcaag actggttctg tataatcacc atccatcgta accaggacat catttgttga
     2641 tgtacgccca cctaaatcgg taactgttac tttatagtaa aactgtcacc tttcgttttt
     2701 tcaggaatag tgaaaccata attcagatta tactcataca atggttctga ataaagagcc
     2761 gacaattcaa ttgtcttgtc caagtaaagc tctgcacatt gtagattgat agaacgaata
     2821 ccgtctttat ctgcaatttt acctgcaatt ttaaattcat agcctgtcaa tgtacggata
     2881 tgatcggacg ttaactcaag agttggagat tgtccgtcta catctctata gtcctcatcg
     2941 tcactacatc caacaaacaa ggtcgctgct gaaaggaaag tccacaaaac cgtgctttgc
     3001 aacaatttag ctttcataat aattagtatt taatgattaa tattatctcg gtacgacttc
     3061 tcaatatata aaatatcggc aaatcgacat gacaaatgta aacgattcca actatataaa
     3121 ccgataaaaa tcatgcagag aagctatata aatcgtgcaa tgcacgattt gcatactcta
     3181 aataaaatat ttattcctat ttttgagctt gtaaatgaaa cgaataatta cgaatcatga
     3241 agaaacacat tgcttctatt ttatttctgt gtctgctatc agtttctcaa tcaatagctc
     3301 aatcccattc tatcaaacga ttgggcattg aacagggatt atctaataat tatgtgatta
     3361 gtatcgcaca agataaacaa ggcttcttat ggtttgctac agaagaagga cttaataaat
     3421 tcgatggcac ccgtttcatt acctattata agaatgactt atcgcaaagt agccaaggaa
     3481 tcactggtaa tgaactcaat cgggtatacg ctgacaataa acgtcccatt atatggatag
     3541 cgactcaacg ggacggatta aatgcatata attacaacaa gcaagcattt acagcttatt
     3601 cacataatcc ggacgatcct catagtttga ttacaaatga tgtaacagac atcgctcctt
     3661 ctgctcaaca cgaagatggc ctgtggatca gtacttatta tagaggcata gaatatctcg
     3721 atattaacag tgggcagttc actcattata acaagaatac agtgccggcc ttatcttgcg
     3781 aacaaacatg gactgtactg gacggagggg atggaaacct atacatcggt catgtcggtc
     3841 acggattcag tattctttca cttaaagata aaaatgtaaa aaacttccag aatcattcgg
     3901 gagacccgaa gagcctgccc ggcaatgatg tgcgatgtct cactaaagat acaaacggta
     3961 atatatggct cgggacagat aaaggcctgg ctcttttcaa tgttgccgat caaagcttta
     4021 tcacttttaa gaataacaaa aatgatagat atgcagcctt atgcaatcgg atattagcta
     4081 ttaaacaatt aaatgacggc aaactttgga tcgcttcaga gcttaatggc attactatac
     4141 tggatctcaa acaaagtatg tttctctcac ccgaacaggt ttccctagaa tatattcagg
     4201 aaggcgatga tagccgaagt ctctccaatg caagtgcccg gtgtatattc caagattctt
     4261 ttgacaacat ctggatagca catgggagga ggaatcaatt ttatcagcag aaagccaccc
     4321 ttattcacaa cattaagtta ttctccgatt cctaacaatg aaaacagcct gaacaataaa
     4381 gtagtgagca gtctctgtac cgacagacaa agacgtatat ggattggaac agacggaggt
     4441 ggtatcaatg tatttgaagg ggacaaacgt attgctattt acagaaaaga aacaggagac
     4501 atcccctcga attttatatt gaccgctttg caggattcaa aaggaaatct atggttcggt
     4561 tcttttcaag gaggaatcag ttattatgat actcggaata aaagatttcg ttccatctct
     4621 ctcatgggac agtacaatca ggatgtccgt acgatctacg aagatactca acacaatatc
     4681 tgggtaggat acagcggagg aatcattgta ttgaatcccc ttaatatgga aattatccga
     4741 cactacaaca cagaaaacag tgaactacat agcgatttcg tacgttctat agctcaagat
     4801 gagaaagggc gcttctggat tggaaccttc ggagacggac ttggcgtata cacgcctgat
     4861 ctacagaaaa tcaagacctt tgtccaaagg gatggtttct gttccaacac cgtcaatcag
     4921 atcatacagg ataagcacaa aaggatgtgg ataggaacag gagaaggact agtatgtttt
     4981 ccttcaaccg atgcattaac ttacaaaaca tatcaacgaa aagatggttt aaccaataca
     5041 aatatctgtg caataaccga agacaagaag ggtaatatat ggtttagcaa taataaaggc
     5101 gttagttgtt atgttacaag taaagactgt ttttacaatt atggtcactc tgatgatgtt
     5161 ccggccggaa gtttctcaag cggttgtgta acacaaaata acaacggatg gatctatttc
     5221 ggttctatca atggcgtatg ttgcttcaat cctgacattg caatgaatga acaacccact
     5281 ccatcggcag ttattacgga aatgaaaata ctcggacgat tgagcaacct ggaaaataat
     5341 gacatgatta tcaatttatc caaaggacag aatgtagaat taagtcatgc gcaaaatagc
     5401 tttggactta catttaacgt acaaaactat tcactagtca accaagtgga atatgtttat
     5461 atgctgaaag ggcttgaaaa ctcatggtac accgtcaatg agaacaacag cgtcactttc
     5521 cgaaacattc ctccgggaaa atatgaattc ctcatcaaag caagggtaca taatcaggaa
     5581 tggccggaag aagcgacttc acttaccatc cgtgtcaatc cccctctttg gctgacatgg
     5641 tgggcaaaac ttatctatat ttgggtatct atcagcatca tttatcttat cctgcatgca
     5701 tataaaaaga agctggattt ggaaagcctc tatacgctgg aaaagaaaaa ccatgagcaa
     5761 gaacaggaat tgaaccagga acgtttgcgg ttctatacta atattaccca tgagctgcgt
     5821 acgccattga ccttaatcct cggtcctttg gaagatatgc aaaaagagac ctcacttccg
     5881 gcaaaacaag ccagaagtta tctgtcatcc atcagagtgc actacggttg ctcaacttga
     5941 ttaatcaaat actggaattc cggaagacag agacacaaaa caagaaattg tgtgtcagca
     6001 aaggcaatat cgctcctctg atctatgaga tagggcttaa atacaaagaa ctaaatcaaa
     6061 agaccaagat tgatttccaa attcagatag agaaagaaga aatgctcctt ttctttgata
     6121 aggaaatcat taccatcgtt ttggacaacc tgatttccaa cgcgatcaaa tatacggaac
     6181 agggacgcgt cactctaagt ttgtatcaga caatgcgcaa tgaggttgct tatacagaga
     6241 taaaagtcag tgacacggga tatggaattt ctgctgaagc cctgccacat atttttgacc
     6301 gttattatca ggaaagcggc aagcatcagg catccggaac aggcattggc ttggccctag
     6361 tgaaaaatct ggtcaccctg catgaaggag aaatccgggc agaaagcata caaaacgaag
     6421 gaagtacttt ctatatcagc ctattgacgg ataatatcta tcccaatgct ttacacgcag
     6481 attctacaga accgattcaa gaagatacga atcaggaagc aagccttgaa tatccacaag
     6541 aaaccacact ggatatcggt aaaccgatcc tgttgattgt agaagacaat gaagagatac
     6601 agaaatatat cgctgagtcc ttcgcagatt cattcgaagt actcactgcc tacaacggag
     6661 aagaagggaa gcaacaagct cttagccgca tcccggatat tgtagtcagc gatattatga
     6721 tgcctgtcat ggacggtatc attctctgcc ggcaattgaa agaggacgta cggaccagtc
     6781 atatccctgt catcctattg acagccaaag actctctgca agataaagaa gaaggatatg
     6841 aggtaggagc cgattcttat ctgacaaagc ctttcagtgc ttctctgctg cgtagccgta
     6901 tcaataatct gctggaatca agaaagaaac tgatagctca attccagaca caatccgttc
     6961 cgggcaatca ggcagattta aaagaaaaac gtatcgtaat cgccgaagct ctaagcaagc
     7021 tggataatga atttattgaa aaaatcaccc ttttaatcga agaaaacctc tcttcggaga
     7081 agattgatat tacctatctt tcagacaaga tgtgtatgag cggttccacc ctctaccgga
     7141 aaatgaaagc actgacagga ttatcgacca acgaatatat ccggaaagtg aaaatgcaaa
     7201 atgcagaacg tttattgctt gaagggaagt tcaacatctc tgaaatcgcc tataaagtag
     7261 gaatgaacag tacggggtat ttccgtcaat gctttaaaga ggaatttggc gtctcgcctt
     7321 cggattacct gaagcagatc atacaatcat aaaaagggag agagccattt acacttaata
     7381 cgttttgaga aacaaattaa gctcctaccg aaaaagaaga gggtaaagtc ataatgccta
     7441 aattaaaagg aaagagtccg gtgctaatac cgaactcttt atctatcttg ctaatttata
     7501 aacctccaac ttttggaggc cacttcaaac gatgcggcag gagtatttct ctaaagaaaa
     7561 gtgttttaac acattcttta taaatctaat tataataaag gaggggagga acctattaaa
     7621 acagaacctg ttaaacagca tctacaaaaa ggatttacaa gtagcagtcg tgcgaactaa
     7681 gtcattccct caattcttca gtcattgtct ttagtaatga cctgctatca cttaacggca
     7741 aatccgtagc taaatcccaa ctcatcatac ctttcagctt ctgttctttt gcataacggg
     7801 ttttgatacg aatgttatcc tgaccgtcaa acacataagt atctccctga tagatcactt
     7861 cattctgtgc aggactcgta accaatccat tctgtacaaa attgaaataa gcctctgtct
     7921 tctttgaatt atctttggtc accccataaa aaggaactcc tgccaccagt ttttccttcg
     7981 gaataccata ctccaatacc atctgtatat ccgaacaata tttctctatc ggaaaacgaa
     8041 ccggtgaagg accatagcac tgaagtgaaa taaaatcaac agcttcaata gcttccttac
     8101 taatcttata acaaacagga tgcagagata cactgaaaag atacttgttt cccaacactt
     8161 cccgcatctt caggatagcc aaactataat ctttatattc tttctcattt tctgcccact
     8221 caaaatcaag atcaatgcca tccagtttat tcttttccag tacagtcttt atgttctttg
     8281 caaacgtcgt acgagcggcc tcatcggcca ccatcgcttt ccattcgcca ctggaagctc
     8341 ccaaacgtat tttcactttt gtacctttta cttttgcacg aaccgattta atcaaacctt
     8401 cccaagtggt cacccctttt ccctgaaatg cacgtggatt ctcaaatgac aatgatccgt
     8461 ctttattagg atgaacattc aagaaaataa ggtcgtcact tgcccgcaag ctttctgtag
     8521 agatacgacc acggttgtaa aaattacccc gcacataaga actgaccata tagtcttgct
     8581 gtgcaaacaa tgataatcca acaaacaaaa aaaagaagaa gaatacaatt tttcttagca
     8641 ttagcataat gattgataat aaaacgttta gattgcaaaa atacgcatat caaagggaaa
     8701 cagatgttca aaaacaacta taatacttcc aaaaatcaac ataaagtttt ctattcagaa
     8761 atttacaaca gataaatatt gaattctcta acatcatcca aagggataag aataatattt
     8821 gcaggtttct actaaaacat aaataaaaga aagagttcca ttttccgcaa aaaaagccta
     8881 tctttgttcc gttaagataa taaatcacgc ataaaactca tgccaagaga ttcattttgc
     8941 atacaatata ccaactgtac gggatgtcca aaaaatgttg agaatatcct tgtatataga
     9001 aacttaccta aaggagagca tatccccaag gataagtgta cgcagaattg tatgcttttt
     9061 atgataaagg gcgaattact tatcaatagc gaagagcatc ccggaataac gttacgcgag
     9121 agacaaattg ttttgcaagc tattggctcc aaggtcgaaa tactggcact gacagatgtg
     9181 gaatacgtta tctactggtt caacgaactg cctttgcttt gcgaagaccg atataaggaa
     9241 atgatggaac aggcggaagc tcctttgacc tacactccac tgattatgag tgaaaggctt
     9301 taccaccttg tcaccagtat gcccgaattc ctcgctgaag aaaacccttg cagcaagtat
     9361 atcgacttaa aatgcaaaga actggttttc ttgattacca acttctatcc gctgccccaa
     9421 ctgggttcat tcttctatcc gatcagcact tatacggaaa gtttccacta tttcgtcatg
     9481 cagaattaca gcaaggtgaa gaacgtggaa gaatttgcgc atctgggagg atatacgacc
     9541 actactttcc gccgactatt caaaaacctc tatggtgtgc ccgtatacga atggatactg
     9601 gaaaagaaac gggaaggaat cctggaagac ctacagcaca ccaaaatgcg aatcactgaa
     9661 atctgtaaca gatacggatt cgactctctg tctcatttcg cacacttctg taaagactct
     9721 tttggcgata ccccacgcgc tctacgcaaa aaagcagccg gcggtgagaa aatcggaaag
     9781 gtacaataaa cagtcccatc ctactaatct gccaatcagt tgcaccatgc gtacatactg
     9841 gctggcatat tgacacattg gcgcattgat ccattattaa agaattattt ctttaattcc
     9901 ttgctcaatc aatctatttc ccctattttt gcagtctgta agaggtgtaa aacgtcgaaa
     9961 ttttagttct aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc
    10021 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctaacatt
    10081 tcacatggcg atgaacttgg ttgcgatcat ctcggctgat ggttacaaca tgatttgtga
    10141 gttcctggga gcaaactggt atgcattagt ggctaccgca ggactggctg ctcttttcgt
    10201 gattcacatc atctacgcat tctggctgac catgcagaat cgcaaagcgc gtggtagcga
    10261 acgctatgca gtggttgaca aaccgaaaac tgtagaatgg gcatctcaaa acatgttggt
    10321 gctgggtctg atcgtcatcg taggtcttgg tttgcacctc ttcaacttct gggcaaaaat
    10381 gcagttgccg gaactgatgc acaacatggg catgcacgct gatacactga cgctggctta
    10441 tgctgccaat ggtgcttatc acatccagca gactttctct tgcccggttt acgtagttct
    10501 ttacctcgtt tggctgtttg cgttgtggtt ccacctgact cacggcttct ggagctctat
    10561 gcaatcactg ggatggaaca acaaagtatg gatcaatcgt tggaaatgca tttctaacat
    10621 ctattctacg attgttgtac tcggtttcgc actggtagta gtggtattct tcgtgaaaac
    10681 actgatttgt ggcggtgctt gctaaatagt aaattgtaaa tgattaaatt gtaaataata
    10741 ttatgatcaa gatagattca aaaattccag aaggcccggt ggctgagaaa tggaccaact
    10801 ataaagctca ccagaaattg gtgaatcccg ctaataaacg tcgtttggac atcatcgttg
    10861 tgggtacagg tctggcaggt gcttctgccg ctgcttcact tggtgaaatg ggtttcagag
    10921 tattcaattt ctgtattcaa gattctcccc gtcgtgcaca ctctatcgct gcacagggtg
    10981 gtatcaatgc tgcaaaaaat tatcaaaatg atggtgactc ggtttaccgt ctgttttacg
    11041 atactgtaaa aggtggcgac tatcgtgccc gtgaagcaaa cgtatatcgt ttggctgaag
    11101 tatccaacgc tatcatcgac caatgtgtag ctcaaggtgt tccttttgct cgcgaatacg
    11161 gtggtacact ggacaaccgt tctttcggtg gtgcacaggt atcacgtact ttctacgcta
    11221 aaggccagac aggtcagcaa ttattgctgg gtgcttactc tgcattgagc cgccaggtaa
    11281 acgtaggtac tgttaaactg tacactcgtt atgaaatgca ggatgttgtc atcgttgacg
    11341 gacgtgctcg cggtattatc gctaaaaacc ttgtaacagg tgaattggaa cgtttcgccg
    11401 ctcacgcagt agttatcgct accggtggtt atggtaacgc ttacttcctg tctaccaacg
    11461 ctatgggttg taactgtaca gctgctatct cttgctaccg caagggtgct gtattcgcta
    11521 accctgcata cgttcagatt cacccgactt gtatccctgt acacggtgac aagcagtcta
    11581 agctgacttt gatgtctgaa tctcttcgta acgacggtcg tatctgggtt ccgaagaaaa
    11641 aagaagatgc tgtgaaactt cagaaaggcg aaatcaaagg aagtgatatt ccggaagaag
    11701 accgcgatta ttacttggaa cgccgctatc cggcattcgg taacctggtt ccgcgtgatg
    11761 ttgccagccg tgctgctaaa gaacgttgcg acgccggttt cggtgtaaac aacaccggtt
    11821 tagccgtatt cctcgatttc tctgaagcta tcaaccgttt gggtatcgat gttgtcctcc
    11881 aacgttatgg taacctcttc gatatgtacg aggaaatcac tgacgttaat ccgggcgaac
    11941 tggcaaaaga aattaatggc gtaaaatatt ataatccgat gatgatttat ccggctatcc
    12001 actacacaat gggaggaatc tgggtagact acgaactgca aaccactatc aagggtctgt
    12061 tcgctatcgg tgaatgtaac ttctccgacc acggtgcaaa ccgcctcggt gcttctgcat
    12121 tgatgcaagg tttggctgac ggttacttcg tattgcctta tacaatccag aattatctgg
    12181 cagatcaaat cactgttcct cgtttctcta ctgatcttcc tgaatttgct gaagcagaaa
    12241 aagcagttca agctaagatc gacaagttca tgagtatcca gggtaaagaa tctgttgatt
    12301 ctatccacaa gaaactgggt catgtcatgt gggaatatgt aggtatggga cgtacggcag
    12361 aaggcttgaa gaaaggtatt gccgaattga aagaaatccg caaggaattc gaaacgaatc
    12421 tgtttatccc cggttccaaa gaaggtatga acgtagagct tgacaaagca atccgtctgt
    12481 acgacttcat cacaatgggt gagcttgttg cttacgatgc attgaaccgt aacgaaagtg
    12541 tggtggtcac ttccgtgaag aataccagac tgaagaagga gaagctaaac gtgatgacga
    12601 aaacttcttc tatgtagcat gttgggaata tcaaggtgac gatgaaaagg ctccggtatt
    12661 gcacaaagaa ccgctggtat acgaagctat caaggttcag actcgtaact acaagagcta
    12721 atcggtgaag ttaaacattt aaaagaatta gaagaaaatg gataaaaata tatcatttac
    12781 actgaaggta tggcgccaag ctggtccgaa agctaaaggt gcttttgaaa cctaccaaat
    12841 gaaagatatc cccggtgata cttccttcct cgaaatgctg gatattctga acgaacagct
    12901 catcagcgaa agaaaagaac cggtagtatt cgatcatgac tgccgcgaag gtatctgcgg
    12961 tatgtgttct ctttacatca acggacaccc gcacggtcct gcaacaggtg ctactacttg
    13021 ccaaatctat atgcgtcgtt tcaacgacgg tgataccatc actgttgaac cttggcgttc
    13081 ggctggtttc cctgtcatca aagacttgat ggtagaccgt actgcatacg acaagattat
    13141 gcaggctggt ggttatgtaa gcgtacgcac aggtgctccg caggatgcta acgctatcct
    13201 gatcgcgaaa cctatcgctg acgaagctat ggatgctgct tcttgtatcg gttgcggtgc
    13261 ttgtgtagct gcatgtaaga atggttctgc tatgttgttc gtttctgcaa aagtcagcca
    13321 gttgaacttg ttgccgcaag gtaaaccgga agctttgcgc cgtgcaaaag ctatgttgtc
    13381 aaagatggat gaactgggat tcggtaactg tacaaacact cgtgcttgtg aagctgaatg
    13441 tccgaagaat atttctatca gcaacatcgc tcgcttgaac cgcgacttca tcatcgcaaa
    13501 attaaaagac tagaaactgc tagatttcaa tagcgagagc ttaatttgat taatgacaga
    13561 atcccctgcc gactagttcg acaggggatt tctttatgta tgagtagatc acaattatta
    13621 ttaatacgga tcagtaacat gaacttttaa ttcataagtt tcaccgattt caccttatag
    13681 ccaaaactgt tatgaatgag agaattacgg gtgaaagcga ggattgaaat aaggtaaaat
    13741 cattcgttac cgcgtaagcg tctccgcgat tctatcttgt cgcccttttt tcattcttat
    13801 atttttgcta tgtataaaaa tgaagcatta tggatttagc agaaaatcga tttggaaaaa
    13861 cttggaaaca tttccttgaa gcattgaaag tagactacaa ttgttcttta gccgatgttt
    13921 gccgcgatca gcataccact tttggtggta tgagttcctg gatgtccaga cggggctata
    13981 gcgttaaaca agccaaggca gatgtggtcc gtgattatta tggcggcgtt gaaccctccc
    14041 aaccgacaac ttcctctcct tcattcactc aaatatcacc cgccatgttg tcggaagaag
    14101 agtttagtct tgccgggatc acaatcacct ttaacagtgg aaccaccatt tcggtcaaac
    14161 gggccacacc cggtggtgtt attaaaatgt tgcgcgatta cgaaagaacg gagggagatc
    14221 catgtattct ctaacatcag ccaatcgcta ctatctgtac cagggctttg ttcgtatgaa
    14281 ccttggcatt gacggtttat tcaaaattat acgatcggaa atgaaggact tgtctcccgt
    14341 ttccggagat atctttttat tctttggtaa aaaccgacaa agtgtaaaaa tactgcgttg
    14401 ggatggcgat ggctttcttc tgtactacaa gcgcctcgaa ggtggaagtt ttgagttacc
    14461 gacatttaac cccaatacag gtaattacga gatttcttat caggttttgt cttttatctt
    14521 aaatggagtg tcattaaagt ctgtacggtt gagaaaacgt tttaggatct aattcaacat
    14581 tttgattatt agttatttgc gctaaggata tcatccggtt tatttggcca attcgttgat
    14641 tttttatatc tttatgccat gaaaaaggat gagatcatag agttattgaa ggaacaaatc
    14701 aagggattac gagatgacaa caacagactc ttggaccaaa tagatgcttt gataaaggag
    14761 gtttcttccc ttaaagaggc actccttcaa aaaggcgaat ctcttagcaa gcaacagcgc
    14821 cttactaagg gactcgccaa acttgtatcc aacacatccg aacagcaaca ggctccccaa
    14881 tctgccatat ccgaagaaga gcggcagaag atagaagcgg aaaaagcaga taagcgtaaa
    14941 gcaagaaaga acaatggggc caaacgtgac atgcattatg agatggagga agaagaacat
    15001 gtcgtttatc ccgatgatcc cgattttgac atcaataagg cccggttgtt taccactgtt
    15061 cccagaatat gcgtccgcta tgaatgtgta cccatgcgct tcatcaagca tgtctacaag
    15121 atacacacct atacgcaaga aggtcgcctg tttgagggaa aaacaccggc ttcggccttc
    15181 ttgaattcca gctatgacgg ttcatttatt gccggattga tggaattacg ttatatacaa
    15241 tcgctacctg ttgaaagaat catcaactac ttcgagagtc atggctttac gctgaagaaa
    15301 cctacggctc ataagttgat agagaaagcc tcagacctct tcgaaaatct ttataagtgc
    15361 atccggcaga cagctttgag tgatccttat aaggcagccg atgaaaccta ttacaaaata
    15421 ctcgtcccgg aaaagaacag caagggaaaa ggagtcagga agggatacct ttgggtggtt
    15481 gtcggcataa acaccaggat gatatacctg ctctatgatg acggctcccg gtctgaaaga
    15541 gttattctta acgaattagg cagttgca
//
